GREMLIN Database
GYRB - DNA gyrase subunit B
UniProt: P05652 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 638 (623)
Sequences: 4828 (2004)
Seq/√Len: 80.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
59_T76_N6.4891.00
141_K158_I4.4911.00
45_I122_A4.3321.00
208_E217_K4.0141.00
130_T172_V4.0081.00
66_E72_T3.7541.00
133_D146_T3.6911.00
173_P184_Y3.6691.00
549_A558_L3.4911.00
148_K153_V3.3291.00
131_E172_V3.2671.00
74_V168_T3.2311.00
137_H164_H3.2231.00
204_N219_E3.1411.00
416_S421_I3.0161.00
590_D593_S3.0141.00
494_H529_Y2.9811.00
60_D204_N2.9471.00
10_E83_G2.9161.00
93_V134_V2.8761.00
133_D144_R2.8671.00
107_D110_G2.7511.00
97_M169_T2.7481.00
66_E210_K2.7361.00
93_V156_L2.7111.00
42_V189_L2.6951.00
197_A222_Y2.6661.00
131_E146_T2.6591.00
491_A529_Y2.6551.00
144_R157_E2.6451.00
88_M95_V2.6411.00
418_D421_I2.6171.00
62_N206_T2.5681.00
135_T168_T2.5571.00
134_V169_T2.5351.00
66_E170_H2.5271.00
72_T170_H2.5211.00
60_D76_N2.5121.00
154_T157_E2.5091.00
302_R313_N2.4781.00
67_K210_K2.4521.00
141_K161_E2.4321.00
424_L478_L2.3961.00
135_T144_R2.3811.00
201_K248_E2.3661.00
93_V136_V2.3511.00
63_I193_V2.3361.00
143_H158_I2.3251.00
82_V143_H2.3201.00
186_Y218_N2.3061.00
62_N74_V2.2901.00
42_V71_I2.2791.00
130_T175_P2.2761.00
65_I71_I2.2721.00
534_Q597_L2.2501.00
629_N632_Y2.2471.00
538_Y552_D2.2441.00
90_R94_E2.2261.00
258_V327_I2.2061.00
419_P494_H2.1841.00
135_T142_I2.1701.00
50_I203_V2.1491.00
474_M478_L2.1261.00
204_N221_H2.1141.00
299_D303_K2.1131.00
186_Y207_I2.1121.00
624_N628_A2.1011.00
10_E92_A2.0871.00
522_R526_E2.0871.00
497_V596_L2.0861.00
133_D170_H2.0711.00
158_I161_E2.0671.00
523_Q526_E2.0561.00
296_V358_S2.0541.00
58_C76_N2.0501.00
72_T168_T2.0221.00
17_E87_K2.0171.00
135_T170_H2.0081.00
281_E342_T2.0071.00
145_Q152_P2.0061.00
541_Q546_V1.9971.00
80_I96_I1.9951.00
149_R176_E1.9841.00
228_S231_E1.9551.00
246_Y257_E1.9511.00
137_H142_I1.9461.00
412_A437_K1.9251.00
415_S442_R1.9121.00
66_E70_S1.9101.00
524_I530_V1.8621.00
272_S286_E1.8561.00
435_S581_A1.8561.00
146_T153_V1.8561.00
274_T331_H1.8361.00
62_N208_E1.8351.00
426_I450_L1.8311.00
194_R232_Y1.8251.00
297_I365_M1.8231.00
142_I162_T1.7951.00
21_A101_H1.7931.00
478_L496_V1.7841.00
238_E264_D1.7841.00
426_I474_M1.7741.00
60_D206_T1.7701.00
64_Q74_V1.7641.00
551_N554_E1.7641.00
90_R99_V1.7481.00
350_R354_D1.7461.00
254_I352_I1.7231.00
314_L379_G1.7221.00
43_W189_L1.7171.00
64_Q210_K1.7131.00
249_G356_L1.7061.00
83_G139_D1.6991.00
272_S279_T1.6861.00
250_E255_T1.6701.00
606_D609_E1.6661.00
398_R401_A1.6631.00
97_M122_A1.6611.00
146_T154_T1.6531.00
368_N371_A1.6521.00
227_K231_E1.6451.00
514_L530_V1.6411.00
142_I160_G1.6151.00
137_H168_T1.6141.00
532_I599_V1.6081.00
487_N490_K1.6071.00
206_T219_E1.6041.00
11_N86_E1.5901.00
17_E88_M1.5901.00
300_Y372_A1.5891.00
478_L491_A1.5841.00
190_A218_N1.5831.00
186_Y220_Y1.5801.00
64_Q208_E1.5691.00
144_R159_I1.5470.99
540_V558_L1.5460.99
289_F325_A1.5450.99
234_N261_Q1.5350.99
122_A132_L1.5270.99
9_D12_Q1.5190.99
71_I184_Y1.5180.99
198_F232_Y1.5050.99
254_I349_A1.5000.99
361_M365_M1.4850.99
83_G92_A1.4770.99
364_F368_N1.4760.99
420_S494_H1.4590.99
289_F327_I1.4560.99
97_M132_L1.4550.99
131_E148_K1.4530.99
555_L559_L1.4430.99
250_E253_G1.4360.99
34_N347_S1.4340.99
416_S422_S1.4310.99
46_V73_V1.4230.99
260_L323_L1.4150.99
147_Y152_P1.4100.99
14_Q107_D1.4060.99
301_A307_I1.4050.99
618_K621_P1.4010.99
349_A352_I1.4000.99
451_R470_E1.3960.99
554_E557_E1.3850.99
83_G138_R1.3850.99
316_G320_R1.3830.99
70_S172_V1.3800.99
523_Q527_N1.3780.99
234_N324_T1.3590.99
422_S494_H1.3470.99
152_P155_D1.3340.98
547_E561_T1.3240.98
74_V164_H1.3200.98
309_E313_N1.3160.98
463_D467_S1.3120.98
542_Q567_K1.3100.98
331_H349_A1.3070.98
103_G106_F1.3030.98
64_Q72_T1.3010.98
571_Q583_Q1.2990.98
321_E382_A1.2880.98
201_K257_E1.2810.98
137_H165_T1.2760.98
469_N473_S1.2760.98
547_E558_L1.2710.98
274_T279_T1.2670.98
604_A607_A1.2660.98
132_L169_T1.2650.98
185_D188_L1.2590.98
424_L474_M1.2590.98
95_V99_V1.2570.98
206_T217_K1.2510.98
454_I471_V1.2480.98
58_C61_I1.2480.98
513_L517_F1.2450.98
50_I196_L1.2410.98
243_E371_A1.2400.98
266_Y397_R1.2360.97
53_A203_V1.2360.97
480_T486_F1.2350.97
172_V175_P1.2350.97
142_I159_I1.2340.97
14_Q24_K1.2340.97
46_V193_V1.2240.97
470_E473_S1.2230.97
539_K546_V1.2210.97
302_R311_D1.2210.97
115_G277_I1.2170.97
496_V517_F1.2160.97
488_L527_N1.2120.97
147_Y154_T1.2110.97
451_R454_I1.2110.97
245_I260_L1.2050.97
84_I89_G1.2010.97
70_S173_P1.2000.97
69_N183_E1.1970.97
30_I37_G1.1940.97
248_E257_E1.1940.97
419_P422_S1.1870.97
226_I246_Y1.1850.97
302_R309_E1.1830.97
360_A363_T1.1810.97
65_I69_N1.1800.97
398_R413_D1.1800.97
280_Y342_T1.1730.97
97_M134_V1.1710.96
421_I443_H1.1710.96
145_Q154_T1.1700.96
227_K246_Y1.1690.96
517_F530_V1.1640.96
57_Y78_R1.1640.96
270_I290_K1.1630.96
297_I319_V1.1610.96
438_Q581_A1.1600.96
547_E554_E1.1600.96
421_I444_F1.1560.96
623_R627_E1.1550.96
454_I500_T1.1500.96
146_T157_E1.1490.96
7_S12_Q1.1480.96
139_D143_H1.1450.96
365_M372_A1.1400.96
540_V549_A1.1360.96
338_G345_G1.1350.96
190_A220_Y1.1340.96
255_T330_K1.1320.96
540_V555_L1.1300.96
256_V356_L1.1290.96
141_K160_G1.1270.96
49_S169_T1.1250.96
559_L570_L1.1200.95
270_I325_A1.1170.95
66_E69_N1.1140.95
147_Y156_L1.1140.95
413_D492_R1.1130.95
378_K397_R1.1120.95
70_S170_H1.1080.95
69_N172_V1.1070.95
585_W591_P1.1050.95
556_E560_K1.1030.95
374_K377_D1.1030.95
281_E338_G1.1000.95
24_K333_D1.0970.95
291_T354_D1.0970.95
480_T488_L1.0970.95
415_S443_H1.0950.95
586_E590_D1.0940.95
426_I470_E1.0920.95
247_I258_V1.0920.95
294_T316_G1.0880.95
549_A555_L1.0880.95
42_V46_V1.0870.95
254_I331_H1.0850.95
462_L466_L1.0780.94
480_T491_A1.0730.94
423_E497_V1.0730.94
542_Q563_P1.0670.94
357_F361_M1.0660.94
70_S131_E1.0650.94
338_G342_T1.0600.94
546_V549_A1.0580.94
557_E561_T1.0540.94
13_I92_A1.0530.94
22_V100_L1.0510.94
510_R532_I1.0480.94
136_V156_L1.0460.93
563_P567_K1.0460.93
301_A376_V1.0450.93
232_Y609_E1.0440.93
186_Y190_A1.0440.93
193_V207_I1.0400.93
329_I349_A1.0400.93
138_R165_T1.0390.93
175_P182_T1.0390.93
256_V352_I1.0390.93
451_R469_N1.0360.93
444_F591_P1.0350.93
235_R609_E1.0350.93
60_D219_E1.0260.93
130_T176_E1.0230.93
337_E345_G1.0220.93
194_R222_Y1.0210.93
491_A527_N1.0180.93
337_E342_T1.0170.92
603_D606_D1.0130.92
137_H162_T1.0080.92
363_T367_E1.0070.92
49_S97_M1.0060.92
74_V137_H1.0050.92
292_G296_V1.0040.92
549_A554_E0.9990.92
149_R174_D0.9980.92
408_P413_D0.9890.91
335_Q345_G0.9840.91
454_I470_E0.9800.91
555_L568_P0.9770.91
274_T329_I0.9770.91
498_I517_F0.9750.91
279_T345_G0.9730.91
354_D358_S0.9720.91
189_L193_V0.9710.91
385_A389_A0.9690.91
142_I164_H0.9680.91
556_E559_L0.9580.90
190_A207_I0.9540.90
91_P95_V0.9520.90
224_G228_S0.9510.90
224_G227_K0.9490.90
454_I473_S0.9460.89
299_D302_R0.9440.89
279_T338_G0.9440.89
472_R476_T0.9440.89
564_Q567_K0.9430.89
287_A291_T0.9430.89
82_V138_R0.9420.89
85_H92_A0.9420.89
41_L125_V0.9390.89
14_Q87_K0.9340.89
7_S10_E0.9340.89
136_V167_T0.9330.89
422_S529_Y0.9280.89
573_Y583_Q0.9270.89
53_A58_C0.9240.88
108_G333_D0.9230.88
59_T204_N0.9210.88
307_I311_D0.9200.88
262_Y319_V0.9200.88
80_I169_T0.9190.88
54_L58_C0.9180.88
351_T355_T0.9180.88
266_Y378_K0.9180.88
412_A442_R0.9170.88
287_A354_D0.9170.88
12_Q110_G0.9160.88
85_H90_R0.9150.88
227_K243_E0.9150.88
80_I97_M0.9140.88
585_W590_D0.9130.88
610_T613_M0.9130.88
122_A134_V0.9120.88
301_A314_L0.9090.88
318_D386_R0.9080.87
454_I468_N0.9020.87
179_S182_T0.9020.87
307_I313_N0.9010.87
45_I97_M0.8990.87
458_E519_R0.8990.87
9_D83_G0.8960.87
359_T363_T0.8960.87
609_E613_M0.8950.87
620_E624_N0.8950.87
243_E368_N0.8940.87
63_I205_I0.8940.87
441_D444_F0.8930.87
63_I207_I0.8910.86
122_A169_T0.8840.86
84_I88_M0.8830.86
518_Y607_A0.8820.86
90_R152_P0.8770.86
91_P156_L0.8750.85
90_R95_V0.8750.85
244_P259_A0.8710.85
474_M500_T0.8710.85
319_V379_G0.8710.85
86_E89_G0.8700.85
425_Y444_F0.8690.85
475_I516_F0.8680.85
468_N473_S0.8660.85
385_A392_A0.8650.85
302_R307_I0.8640.85
274_T345_G0.8600.84
65_I207_I0.8580.84
142_I158_I0.8570.84
410_K430_D0.8530.84
241_H371_A0.8520.84
370_D374_K0.8490.84
196_L200_T0.8470.84
281_E343_K0.8440.83
466_L471_V0.8430.83
470_E500_T0.8420.83
287_A350_R0.8390.83
50_I205_I0.8380.83
174_D177_I0.8380.83
295_R354_D0.8360.83
84_I90_R0.8350.83
224_G231_E0.8350.83
76_N164_H0.8320.82
15_V88_M0.8310.82
539_K583_Q0.8310.82
198_F222_Y0.8310.82
145_Q156_L0.8300.82
92_A95_V0.8290.82
377_D381_M0.8290.82
438_Q580_N0.8280.82
16_L24_K0.8230.82
21_A27_G0.8200.82
144_R154_T0.8190.81
591_P594_R0.8190.81
611_F615_M0.8170.81
69_N184_Y0.8150.81
86_E92_A0.8150.81
373_K377_D0.8130.81
489_E527_N0.8130.81
272_S338_G0.8130.81
139_D158_I0.8110.81
510_R534_Q0.8090.81
194_R198_F0.8080.81
149_R177_I0.8080.81
57_Y151_V0.8040.80
35_S185_D0.8020.80
298_N302_R0.8010.80
437_K583_Q0.8000.80
162_T165_T0.7930.79
358_S362_E0.7930.79
601_L607_A0.7920.79
274_T336_F0.7900.79
582_T590_D0.7880.79
171_F184_Y0.7870.79
241_H262_Y0.7860.79
132_L145_Q0.7860.79
314_L376_V0.7840.79
19_L100_L0.7810.78
241_H244_P0.7810.78
612_E618_K0.7800.78
279_T337_E0.7780.78
624_N627_E0.7780.78
272_S345_G0.7770.78
208_E213_G0.7760.78
88_M99_V0.7760.78
346_N349_A0.7720.77
621_P624_N0.7710.77
248_E255_T0.7700.77
457_V465_I0.7680.77
395_L398_R0.7670.77
256_V353_T0.7670.77
600_T604_A0.7650.77
258_V289_F0.7640.77
43_W188_L0.7640.77
21_A100_L0.7630.77
552_D556_E0.7630.77
258_V357_F0.7620.77
15_V95_V0.7580.76
130_T174_D0.7570.76
17_E21_A0.7560.76
525_I530_V0.7550.76
18_G22_V0.7540.76
130_T149_R0.7530.76
419_P529_Y0.7530.76
59_T63_I0.7500.75
499_M533_A0.7480.75
409_G442_R0.7470.75
425_Y596_L0.7440.75
525_I601_L0.7440.75
436_A447_I0.7410.75
408_P492_R0.7390.74
414_C492_R0.7390.74
474_M516_F0.7370.74
289_F357_F0.7370.74
409_G477_A0.7360.74
480_T521_M0.7350.74
21_A24_K0.7350.74
407_L442_R0.7340.74
606_D610_T0.7340.74
32_S37_G0.7340.74
14_Q17_E0.7330.74
241_H261_Q0.7330.74
469_N472_R0.7320.74
83_G143_H0.7320.74
560_K563_P0.7310.74
270_I286_E0.7300.73
540_V562_L0.7290.73
141_K159_I0.7290.73
422_S491_A0.7280.73
85_H95_V0.7270.73
17_E151_V0.7270.73
291_T350_R0.7260.73
68_D170_H0.7250.73
295_R358_S0.7250.73
272_S335_Q0.7240.73
625_F630_A0.7240.73
296_V361_M0.7220.73
87_K151_V0.7200.72
231_E243_E0.7190.72
82_V93_V0.7180.72
54_L207_I0.7180.72
520_Y550_Y0.7170.72
159_I162_T0.7170.72
19_L101_H0.7170.72
254_I332_P0.7160.72
542_Q566_P0.7160.72
10_E139_D0.7150.72
483_G520_Y0.7130.72
425_Y585_W0.7130.72
583_Q586_E0.7130.72
546_V586_E0.7100.71
260_L293_L0.7090.71
94_E145_Q0.7080.71
249_G360_A0.7080.71
279_T335_Q0.7070.71
625_F629_N0.7050.71
334_P413_D0.7030.71
281_E347_S0.7020.71
451_R471_V0.7010.70
175_P183_E0.7010.70
180_E183_E0.7000.70
416_S443_H0.6980.70
478_L494_H0.6980.70
133_D148_K0.6980.70
478_L530_V0.6980.70
420_S529_Y0.6960.70
142_I163_D0.6960.70
99_V147_Y0.6960.70
131_E153_V0.6950.70
499_M589_M0.6950.70
523_Q601_L0.6950.70
19_L22_V0.6930.70
228_S473_S0.6910.69
457_V471_V0.6900.69
142_I161_E0.6890.69
234_N263_N0.6890.69
335_Q346_N0.6880.69
372_A376_V0.6870.69
137_H163_D0.6870.69
381_M397_R0.6870.69
102_A123_S0.6870.69
278_N286_E0.6870.69
12_Q107_D0.6860.69
281_E337_E0.6840.69
230_V326_I0.6830.68
290_K320_R0.6810.68
473_S476_T0.6810.68
64_Q70_S0.6800.68
12_Q109_S0.6790.68
195_E229_Y0.6780.68
553_K557_E0.6750.68
89_G151_V0.6740.67
93_V145_Q0.6730.67
296_V362_E0.6730.67
8_Y13_I0.6730.67
385_A396_T0.6730.67
102_A106_F0.6710.67
144_R160_G0.6700.67
68_D172_V0.6690.67
131_E170_H0.6690.67
511_T611_F0.6680.67
306_L376_V0.6670.67
447_I589_M0.6650.66
202_G221_H0.6650.66
305_G310_N0.6640.66
364_F371_A0.6640.66
475_I482_I0.6630.66
408_P473_S0.6630.66
553_K556_E0.6620.66
146_T172_V0.6600.66
398_R403_E0.6600.66
451_R474_M0.6590.66
573_Y586_E0.6590.66
201_K246_Y0.6570.65
587_T594_R0.6570.65
95_V229_Y0.6550.65
406_N476_T0.6550.65
84_I87_K0.6540.65
174_D279_T0.6540.65
319_V467_S0.6540.65
507_A583_Q0.6540.65
244_P247_I0.6520.65
155_D158_I0.6510.65
381_M384_R0.6510.65
488_L491_A0.6500.65
611_F616_G0.6500.65
571_Q585_W0.6490.64
560_K564_Q0.6490.64
615_M619_V0.6480.64
548_Y583_Q0.6480.64
286_E296_V0.6470.64
239_V244_P0.6450.64
540_V559_L0.6430.64
25_R117_L0.6430.64
312_P387_M0.6430.64
388_A392_A0.6430.64
22_V123_S0.6420.64
414_C625_F0.6410.64
72_T210_K0.6410.64
92_A110_G0.6410.64
284_T347_S0.6400.63
238_E618_K0.6400.63
272_S327_I0.6390.63
41_L279_T0.6380.63
516_F521_M0.6380.63
547_E562_L0.6370.63
164_H168_T0.6370.63
589_M594_R0.6350.63
143_H165_T0.6350.63
321_E378_K0.6340.63
334_P457_V0.6320.62
106_F118_H0.6310.62
60_D74_V0.6290.62
130_T146_T0.6290.62
172_V184_Y0.6280.62
304_K376_V0.6270.62
558_L561_T0.6260.62
24_K141_K0.6250.62
268_S320_R0.6240.61
91_P155_D0.6230.61
550_Y558_L0.6230.61
253_G332_P0.6220.61
380_L390_K0.6220.61
554_E595_T0.6210.61
415_S422_S0.6210.61
342_T346_N0.6210.61
462_L465_I0.6200.61
301_A305_G0.6180.61
620_E623_R0.6160.60
36_K280_Y0.6150.60
97_M152_P0.6150.60
314_L380_L0.6150.60
72_T131_E0.6140.60
90_R155_D0.6140.60
49_S61_I0.6140.60
15_V21_A0.6130.60
84_I91_P0.6120.60
82_V141_K0.6110.60
534_Q595_T0.6110.60
302_R310_N0.6100.60
83_G86_E0.6090.60
416_S419_P0.6090.60
142_I147_Y0.6080.59
62_N72_T0.6080.59
496_V530_V0.6080.59
451_R500_T0.6070.59
371_A374_K0.6070.59
541_Q569_G0.6060.59
424_L496_V0.6060.59
305_G309_E0.6050.59
329_I353_T0.6040.59
97_M145_Q0.6040.59
189_L205_I0.6040.59
425_Y495_K0.6040.59
46_V63_I0.6030.59
145_Q155_D0.6030.59
412_A583_Q0.6030.59
465_I471_V0.6010.59
97_M167_T0.6010.59
437_K442_R0.6000.58
91_P152_P0.6000.58
84_I93_V0.5980.58
558_L562_L0.5980.58
135_T207_I0.5980.58
274_T338_G0.5970.58
301_A309_E0.5970.58
251_K352_I0.5960.58
455_L465_I0.5950.58
148_K154_T0.5940.58
422_S443_H0.5940.58
451_R473_S0.5920.57
140_G163_D0.5920.57
292_G361_M0.5920.57
239_V261_Q0.5920.57
45_I124_V0.5920.57
69_N173_P0.5910.57
196_L276_N0.5900.57
30_I33_T0.5900.57
423_E495_K0.5900.57
196_L203_V0.5890.57
111_Y332_P0.5890.57
526_E601_L0.5890.57
550_Y595_T0.5890.57
555_L570_L0.5880.57
281_E346_N0.5860.57
390_K394_E0.5850.57
217_K221_H0.5850.57
491_A524_I0.5850.57
424_L491_A0.5850.57
579_M584_L0.5840.56
63_I212_E0.5840.56
247_I357_F0.5830.56
207_I218_N0.5830.56
256_V365_M0.5830.56
11_N87_K0.5830.56
32_S345_G0.5820.56
532_I617_D0.5810.56
7_S11_N0.5810.56
204_N223_E0.5810.56
384_R461_R0.5810.56
60_D208_E0.5800.56
500_T510_R0.5800.56
417_K557_E0.5790.56
421_I494_H0.5780.56
436_A499_M0.5780.56
190_A273_F0.5780.56
286_E404_I0.5780.56
85_H88_M0.5780.56
616_G626_I0.5770.56
563_P568_P0.5770.56
143_H147_Y0.5770.56
83_G95_V0.5760.55
418_D422_S0.5760.55
18_G101_H0.5750.55
273_F309_E0.5750.55
455_L460_A0.5750.55
370_D373_K0.5750.55
88_M91_P0.5750.55
507_A510_R0.5740.55
451_R466_L0.5740.55
475_I481_G0.5740.55
227_K257_E0.5740.55
611_F618_K0.5740.55
455_L468_N0.5730.55
82_V85_H0.5730.55
271_Y605_M0.5730.55
302_R550_Y0.5720.55
519_R608_D0.5710.55
380_L384_R0.5710.55
424_L480_T0.5700.55
49_S167_T0.5700.55
223_E243_E0.5700.55
138_R256_V0.5690.55
439_G454_I0.5670.54
66_E208_E0.5670.54
231_E244_P0.5670.54
387_M390_K0.5670.54
413_D422_S0.5670.54
37_G340_T0.5660.54
572_R578_E0.5660.54
91_P154_T0.5650.54
36_K342_T0.5650.54
489_E494_H0.5650.54
450_L513_L0.5640.54
253_G331_H0.5640.54
233_L324_T0.5640.54
438_Q442_R0.5630.54
69_N182_T0.5630.54
441_D591_P0.5630.54
510_R597_L0.5620.54
396_T399_K0.5620.54
73_V169_T0.5620.54
306_L380_L0.5610.53
322_G378_K0.5590.53
395_L475_I0.5580.53
389_A392_A0.5570.53
200_T276_N0.5570.53
34_N342_T0.5560.53
334_P492_R0.5560.53
440_R445_Q0.5550.53
151_V174_D0.5550.53
439_G585_W0.5550.53
602_E606_D0.5550.53
398_R402_L0.5550.53
514_L611_F0.5540.53
396_T485_D0.5520.52
407_L412_A0.5510.52
454_I469_N0.5510.52
11_N85_H0.5500.52
187_D190_A0.5480.52
27_G498_I0.5480.52
294_T298_N0.5480.52
42_V65_I0.5470.52
12_Q108_G0.5440.51
552_D555_L0.5440.51
274_T332_P0.5430.51
96_I169_T0.5430.51
15_V194_R0.5420.51
109_S112_K0.5420.51
306_L309_E0.5400.51
80_I93_V0.5390.51
27_G108_G0.5390.51
135_T159_I0.5380.50
94_E114_S0.5370.50
192_R196_L0.5370.50
606_D628_A0.5370.50
290_K316_G0.5370.50
331_H468_N0.5360.50
67_K213_G0.5360.50
422_S492_R0.5360.50
227_K244_P0.5360.50
559_L562_L0.5360.50
568_P631_R0.5350.50
332_P352_I0.5350.50
337_E343_K0.5350.50
108_G332_P0.5350.50
302_R308_K0.5340.50
557_E560_K0.5340.50
401_A404_I0.5340.50
460_A465_I0.5340.50
515_T615_M0.5340.50
249_G263_N0.5340.50
398_R422_S0.5340.50
65_I211_R0.5330.50
542_Q568_P0.5330.50
404_I476_T0.5330.50
74_V135_T0.5330.50
15_V99_V0.5330.50
356_L596_L0.5330.50
309_E379_G0.5330.50
6_N9_D0.5330.50
608_D612_E0.5320.50
307_I380_L0.5320.50
538_Y571_Q0.5320.50
33_T345_G0.5310.50
424_L530_V0.5310.50
62_N204_N0.5310.50
69_N131_E0.5310.50
589_M627_E0.5300.49
44_E48_N0.5290.49
35_S188_L0.5290.49
236_S239_V0.5290.49
500_T507_A0.5280.49
278_N342_T0.5280.49
133_D153_V0.5280.49
439_G507_A0.5270.49
522_R623_R0.5270.49
464_K625_F0.5270.49
315_S393_R0.5270.49
542_Q562_L0.5270.49
378_K389_A0.5260.49
236_S612_E0.5260.49
404_I472_R0.5260.49
19_L127_A0.5260.49
299_D358_S0.5260.49
462_L482_I0.5260.49
584_L587_T0.5260.49
401_A413_D0.5250.49
136_V169_T0.5250.49
52_E78_R0.5250.49
34_N620_E0.5250.49
471_V516_F0.5240.49
573_Y580_N0.5240.49
96_I278_N0.5240.49
18_G24_K0.5240.49
16_L27_G0.5240.49
416_S420_S0.5240.49
18_G21_A0.5230.49
286_E290_K0.5230.49
352_I356_L0.5230.49
286_E363_T0.5230.49
579_M587_T0.5230.49
234_N237_K0.5220.48
62_N217_K0.5210.48
133_D168_T0.5210.48
155_D297_I0.5210.48
316_G322_G0.5210.48
426_I430_D0.5200.48
58_C77_G0.5200.48
237_K612_E0.5200.48
43_W205_I0.5200.48
580_N583_Q0.5190.48
45_I277_I0.5190.48
162_T168_T0.5180.48
550_Y555_L0.5180.48
34_N346_N0.5170.48
93_V132_L0.5170.48
310_N313_N0.5160.48
36_K346_N0.5160.48
49_S384_R0.5160.48
104_G114_S0.5160.48
391_K394_E0.5150.48
16_L22_V0.5140.47
54_L330_K0.5140.47
299_D362_E0.5140.47
85_H438_Q0.5130.47
550_Y573_Y0.5130.47
550_Y554_E0.5120.47
342_T345_G0.5120.47
22_V26_P0.5120.47
425_Y591_P0.5110.47
436_A584_L0.5110.47
307_I310_N0.5110.47
99_V152_P0.5110.47
376_V379_G0.5110.47
473_S500_T0.5100.47
321_E393_R0.5100.47
219_E489_E0.5100.47
98_T152_P0.5100.47
93_V279_T0.5090.47
417_K494_H0.5090.47
48_N51_D0.5090.47
59_T163_D0.5090.47
611_F621_P0.5080.47
15_V18_G0.5080.47
82_V383_A0.5080.47
425_Y510_R0.5080.47
71_I207_I0.5080.47
534_Q550_Y0.5070.46
563_P566_P0.5070.46
196_L334_P0.5070.46
16_L25_R0.5070.46
334_P422_S0.5060.46
124_V128_L0.5050.46
518_Y601_L0.5050.46
154_T158_I0.5040.46
221_H485_D0.5040.46
305_G308_K0.5040.46
107_D302_R0.5040.46
175_P179_S0.5040.46
385_A398_R0.5040.46
250_E561_T0.5040.46
389_A396_T0.5040.46
507_A541_Q0.5040.46
36_K279_T0.5030.46
11_N83_G0.5030.46
586_E593_S0.5030.46
251_K355_T0.5030.46
465_I500_T0.5030.46
374_K529_Y0.5020.46
615_M626_I0.5020.46
65_I186_Y0.5020.46
608_D611_F0.5020.46
186_Y211_R0.5010.46
398_R408_P0.5010.46
495_K531_Y0.5010.46
53_A202_G0.5010.46
294_T320_R0.5000.46
15_V101_H0.5000.46
179_S347_S0.5000.46
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4i3hA 2 0.8824 100 0.071 Contact Map
4gfhA 2 0.9107 100 0.137 Contact Map
3zkbA 5 0.6097 100 0.527 Contact Map
4urlA 1 0.569 100 0.552 Contact Map
4wubA 2 0.6003 100 0.554 Contact Map
1zxmA 2 0.547 100 0.557 Contact Map
1pvgA 2 0.5439 100 0.562 Contact Map
3lnuA 1 0.5345 100 0.565 Contact Map
3nuhB 1 0.2947 100 0.566 Contact Map
1kijA 2 0.5987 100 0.575 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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