DNAA - BACSU - GREMLIN Contacts

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DNAA - Chromosomal replication initiator protein DnaA

UniProt:	P05648	Sequences: MENILDLWNQALAQIEKKLSKPSFETWMKSTKAHSLQGDTLTITAPNEFARDWLESRYLHLIADTIYELTGEELSIKFVIPQNQDVEDFMPKPQVKKAVKEDTSDFPQNMLNPKYTFDTFVIGSGNRFAHAASLAVAEAPAKAYNPLFIYGGVGLGKTHLMHAIGHYVIDHNPSAKVVYLSSEKFTNEFINSIRDNKAVDFRNRYRNVDVLLIDDIQFLAGKEQTQEEFFHTFNTLHEESKQIVISSDRPPKEIPTLEDRLRSRFEWGLITDITPPDLETRIAILRKKAKAEGLDIPNEVMLYIANQIDSNIRELEGALIRVVAYSSLINKDINADLAAEALKDIIPSSKPKVITIKEIQRVVGQQFNIKLEDFKAKKRTKSVAFPRQIAMYLSREMTDSSLPKIGEEFGGRDHTTVIHAHEKISKLLADDEQLQQHVKEIKEQLK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	446 (437)
Sequences:	2877 (1876)
Seq/√Len:	89.7

ECOLI - DNAA
BACSU - DNAA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
391_M	417_V	4.151	1.00
164_I	244_V	3.477	1.00
167_Y	170_D	3.426	1.00
168_V	210_V	3.335	1.00
132_A	269_L	3.284	1.00
33_A	41_L	3.196	1.00
286_R	298_N	3.132	1.00
356_I	360_Q	3.046	1.00
428_L	438_V	3.003	1.00
406_G	411_G	2.970	1.00
172_N	175_A	2.950	1.00
300_V	338_A	2.931	1.00
206_R	232_T	2.912	1.00
367_F	437_H	2.881	1.00
396_E	442_K	2.723	1.00
51_R	55_E	2.659	1.00
428_L	435_Q	2.622	1.00
421_H	425_S	2.555	1.00
197_K	200_D	2.520	1.00
415_T	418_I	2.512	1.00
237_H	267_W	2.474	1.00
435_Q	439_K	2.460	1.00
356_I	394_S	2.442	1.00
406_G	410_G	2.383	1.00
360_Q	375_K	2.316	1.00
124_S	127_R	2.296	1.00
53_W	57_R	2.286	1.00
136_V	147_L	2.284	1.00
188_E	205_Y	2.272	1.00
25_E	29_K	2.269	1.00
390_A	409_F	2.264	1.00
31_T	43_I	2.234	1.00
178_V	208_V	2.183	1.00
229_F	245_I	2.146	1.00
406_G	412_R	2.134	1.00
14_Q	68_E	2.129	1.00
252_K	266_E	2.123	1.00
367_F	389_I	2.122	1.00
263_S	311_N	2.121	1.00
122_I	130_H	2.118	1.00
183_E	206_R	2.117	1.00
424_I	434_L	2.101	1.00
188_E	204_R	2.100	1.00
288_K	316_E	2.079	1.00
65_T	69_L	2.076	1.00
278_L	282_I	2.065	1.00
360_Q	409_F	2.052	1.00
130_H	134_L	2.046	1.00
189_F	224_Q	2.037	1.00
364_G	371_L	2.029	1.00
285_L	319_L	2.004	1.00
167_Y	171_H	1.985	1.00
21_K	25_E	1.984	1.00
356_I	408_E	1.973	1.00
186_T	225_T	1.960	1.00
36_L	41_L	1.958	1.00
18_K	61_L	1.926	1.00
41_L	66_I	1.918	1.00
428_L	434_L	1.918	1.00
320_I	327_S	1.917	1.00
370_K	373_D	1.906	1.00
212_L	244_V	1.906	1.00
427_L	431_D	1.906	1.00
303_Y	346_I	1.905	1.00
132_A	147_L	1.904	1.00
366_Q	437_H	1.867	1.00
427_L	434_L	1.837	1.00
183_E	218_F	1.824	1.00
282_I	301_M	1.819	1.00
193_I	198_A	1.817	1.00
396_E	425_S	1.810	1.00
35_S	42_T	1.774	1.00
336_D	339_A	1.767	1.00
34_H	44_T	1.766	1.00
189_F	201_F	1.763	1.00
212_L	246_S	1.761	1.00
282_I	302_L	1.758	1.00
40_T	77_K	1.744	1.00
63_A	73_E	1.736	1.00
202_R	228_E	1.715	1.00
388_Q	391_M	1.689	1.00
426_K	430_D	1.686	1.00
54_L	78_F	1.677	1.00
183_E	232_T	1.665	1.00
289_A	301_M	1.655	1.00
31_T	45_A	1.653	1.00
206_R	228_E	1.649	1.00
409_F	420_A	1.630	1.00
137_A	167_Y	1.626	1.00
297_P	300_V	1.622	1.00
402_L	421_H	1.614	1.00
360_Q	371_L	1.601	1.00
216_I	245_I	1.601	1.00
393_L	442_K	1.593	1.00
361_R	365_Q	1.582	1.00
111_L	165_G	1.570	1.00
388_Q	419_H	1.563	1.00
228_E	232_T	1.555	1.00
356_I	400_S	1.548	1.00
180_L	205_Y	1.548	1.00
39_D	72_E	1.535	1.00
70_T	74_L	1.533	1.00
67_Y	73_E	1.521	1.00
357_K	408_E	1.513	1.00
279_E	283_A	1.504	1.00
366_Q	440_E	1.499	1.00
44_T	81_P	1.495	1.00
300_V	335_A	1.491	1.00
230_F	260_R	1.491	1.00
371_L	375_K	1.479	1.00
285_L	315_L	1.472	1.00
13_A	16_E	1.465	0.99
121_V	287_K	1.460	0.99
269_L	324_A	1.452	0.99
373_D	378_K	1.450	0.99
311_N	314_E	1.443	0.99
391_M	420_A	1.440	0.99
234_N	238_E	1.439	0.99
392_Y	438_V	1.439	0.99
117_F	163_A	1.438	0.99
153_V	263_S	1.432	0.99
128_F	324_A	1.426	0.99
24_F	28_M	1.412	0.99
16_E	21_K	1.404	0.99
404_K	407_E	1.397	0.99
59_L	78_F	1.395	0.99
423_K	427_L	1.393	0.99
129_A	160_L	1.391	0.99
286_R	301_M	1.388	0.99
61_L	65_T	1.377	0.99
285_L	301_M	1.370	0.99
16_E	29_K	1.362	0.99
206_R	231_H	1.353	0.99
11_A	66_I	1.353	0.99
423_K	426_K	1.352	0.99
254_I	257_L	1.350	0.99
63_A	75_S	1.343	0.99
296_I	301_M	1.341	0.99
168_V	175_A	1.338	0.99
15_I	28_M	1.330	0.99
365_Q	444_Q	1.317	0.99
304_I	322_V	1.309	0.99
16_E	24_F	1.291	0.99
440_E	444_Q	1.283	0.99
434_L	437_H	1.278	0.99
28_M	54_L	1.278	0.99
335_A	339_A	1.277	0.99
189_F	193_I	1.277	0.99
321_R	344_D	1.270	0.99
36_L	74_L	1.269	0.99
303_Y	335_A	1.260	0.98
12_L	28_M	1.259	0.98
178_V	204_R	1.252	0.98
133_S	164_I	1.249	0.98
146_P	242_Q	1.247	0.98
45_A	78_F	1.243	0.98
308_I	318_A	1.237	0.98
131_A	283_A	1.234	0.98
213_I	216_I	1.220	0.98
32_K	44_T	1.202	0.98
333_I	337_L	1.195	0.98
47_N	50_A	1.193	0.98
219_L	254_I	1.182	0.98
361_R	371_L	1.176	0.98
169_I	177_V	1.173	0.98
182_S	219_L	1.171	0.98
161_M	212_L	1.168	0.97
227_E	231_H	1.167	0.97
28_M	31_T	1.163	0.97
326_S	337_L	1.160	0.97
12_L	24_F	1.155	0.97
385_F	427_L	1.151	0.97
231_H	234_N	1.145	0.97
140_P	242_Q	1.137	0.97
360_Q	374_F	1.132	0.97
261_L	265_F	1.131	0.97
377_K	412_R	1.131	0.97
136_V	242_Q	1.130	0.97
403_P	415_T	1.126	0.97
281_R	308_I	1.119	0.97
152_G	155_L	1.117	0.97
394_S	409_F	1.116	0.97
248_D	260_R	1.110	0.97
186_T	190_I	1.094	0.96
155_L	280_T	1.093	0.96
233_F	243_I	1.091	0.96
32_K	81_P	1.091	0.96
10_Q	69_L	1.087	0.96
203_N	207_N	1.085	0.96
111_L	161_M	1.084	0.96
40_T	75_S	1.083	0.96
14_Q	18_K	1.083	0.96
298_N	302_L	1.071	0.96
322_V	338_A	1.067	0.96
243_I	257_L	1.064	0.96
441_I	445_L	1.064	0.96
151_G	273_I	1.062	0.96
134_L	167_Y	1.056	0.95
259_D	262_R	1.052	0.95
388_Q	416_T	1.042	0.95
46_P	50_A	1.039	0.95
439_K	442_K	1.037	0.95
425_S	429_A	1.037	0.95
432_E	435_Q	1.033	0.95
400_S	404_K	1.031	0.95
141_A	242_Q	1.031	0.95
18_K	64_D	1.028	0.95
395_R	422_E	1.025	0.95
357_K	360_Q	1.022	0.95
52_D	55_E	1.022	0.95
7_L	70_T	1.021	0.94
369_I	374_F	1.015	0.94
14_Q	69_L	1.014	0.94
15_I	61_L	1.013	0.94
51_R	78_F	1.013	0.94
9_N	13_A	1.008	0.94
138_E	171_H	1.006	0.94
111_L	166_H	1.001	0.94
48_E	52_D	1.000	0.94
218_F	231_H	0.999	0.94
394_S	398_T	0.998	0.94
230_F	233_F	0.995	0.94
189_F	198_A	0.994	0.94
326_S	333_I	0.992	0.94
22_P	26_T	0.990	0.94
30_S	50_A	0.981	0.93
59_L	63_A	0.980	0.93
366_Q	444_Q	0.978	0.93
337_L	341_A	0.972	0.93
23_S	58_Y	0.970	0.93
49_F	53_W	0.970	0.93
292_E	320_I	0.967	0.93
223_E	256_T	0.966	0.93
288_K	319_L	0.966	0.93
196_N	224_Q	0.965	0.93
52_D	56_S	0.961	0.93
278_L	302_L	0.959	0.92
5_L	32_K	0.956	0.92
235_T	238_E	0.956	0.92
14_Q	17_K	0.950	0.92
97_K	100_K	0.948	0.92
367_F	386_P	0.944	0.92
418_I	422_E	0.940	0.92
362_V	444_Q	0.937	0.92
360_Q	408_E	0.934	0.91
213_I	245_I	0.933	0.91
434_L	438_V	0.930	0.91
45_A	80_I	0.928	0.91
362_V	445_L	0.924	0.91
235_T	239_E	0.924	0.91
183_E	187_N	0.919	0.91
249_R	259_D	0.915	0.91
191_N	195_D	0.910	0.90
209_D	241_K	0.909	0.90
53_W	58_Y	0.906	0.90
148_F	270_I	0.903	0.90
374_F	390_A	0.900	0.90
6_D	9_N	0.900	0.90
168_V	171_H	0.897	0.90
321_R	325_Y	0.896	0.90
417_V	420_A	0.887	0.89
338_A	399_D	0.887	0.89
402_L	417_V	0.885	0.89
266_E	270_I	0.885	0.89
125_G	280_T	0.884	0.89
43_I	78_F	0.880	0.89
236_L	241_K	0.880	0.89
206_R	218_F	0.877	0.89
379_R	419_H	0.873	0.88
114_K	240_S	0.872	0.88
230_F	248_D	0.872	0.88
257_L	261_L	0.871	0.88
27_W	53_W	0.867	0.88
395_R	402_L	0.866	0.88
331_K	340_E	0.865	0.88
364_G	369_I	0.860	0.88
331_K	337_L	0.858	0.88
429_A	435_Q	0.857	0.87
363_V	367_F	0.855	0.87
389_I	438_V	0.852	0.87
394_S	397_M	0.849	0.87
389_I	393_L	0.848	0.87
402_L	418_I	0.847	0.87
145_N	242_Q	0.847	0.87
33_A	36_L	0.840	0.86
331_K	334_N	0.837	0.86
390_A	394_S	0.836	0.86
111_L	162_H	0.835	0.86
45_A	54_L	0.833	0.86
137_A	168_V	0.831	0.86
192_S	198_A	0.829	0.86
12_L	29_K	0.828	0.86
250_P	254_I	0.822	0.85
233_F	242_Q	0.821	0.85
123_G	277_D	0.820	0.85
24_F	29_K	0.820	0.85
220_A	254_I	0.820	0.85
166_H	270_I	0.819	0.85
322_V	333_I	0.819	0.85
19_L	28_M	0.818	0.85
359_I	398_T	0.816	0.85
37_Q	40_T	0.814	0.85
213_I	229_F	0.813	0.85
97_K	101_E	0.813	0.85
395_R	418_I	0.809	0.84
318_A	342_L	0.803	0.84
18_K	65_T	0.802	0.84
433_Q	439_K	0.801	0.84
42_T	79_V	0.800	0.84
246_S	256_T	0.800	0.84
200_D	203_N	0.798	0.83
302_L	306_N	0.796	0.83
165_G	177_V	0.795	0.83
180_L	310_S	0.795	0.83
218_F	222_K	0.795	0.83
217_Q	245_I	0.794	0.83
31_T	54_L	0.792	0.83
230_F	234_N	0.792	0.83
123_G	155_L	0.791	0.83
219_L	271_T	0.790	0.83
378_K	383_V	0.789	0.83
24_F	58_Y	0.789	0.83
58_Y	61_L	0.787	0.83
66_I	76_I	0.786	0.83
193_I	202_R	0.786	0.83
136_V	145_N	0.785	0.82
340_E	343_K	0.780	0.82
384_A	419_H	0.779	0.82
99_V	102_D	0.778	0.82
360_Q	390_A	0.775	0.82
180_L	188_E	0.774	0.82
398_T	401_S	0.774	0.82
398_T	403_P	0.773	0.81
217_Q	248_D	0.771	0.81
44_T	79_V	0.768	0.81
145_N	233_F	0.768	0.81
161_M	244_V	0.766	0.81
354_I	445_L	0.759	0.80
135_A	283_A	0.757	0.80
186_T	222_K	0.755	0.80
262_R	266_E	0.754	0.80
385_F	412_R	0.752	0.80
55_E	59_L	0.749	0.79
183_E	228_E	0.748	0.79
116_T	166_H	0.741	0.79
233_F	237_H	0.740	0.79
206_R	236_L	0.739	0.78
395_R	421_H	0.739	0.78
319_L	342_L	0.734	0.78
352_K	386_P	0.733	0.78
427_L	430_D	0.732	0.78
169_I	173_P	0.732	0.78
255_P	320_I	0.731	0.78
418_I	421_H	0.731	0.78
287_K	290_K	0.728	0.77
158_T	248_D	0.728	0.77
118_D	167_Y	0.727	0.77
42_T	77_K	0.726	0.77
391_M	409_F	0.726	0.77
45_A	50_A	0.725	0.77
300_V	333_I	0.722	0.77
385_F	437_H	0.722	0.77
322_V	341_A	0.721	0.77
14_Q	65_T	0.721	0.77
181_S	184_K	0.719	0.77
7_L	33_A	0.718	0.76
303_Y	384_A	0.718	0.76
269_L	321_R	0.716	0.76
27_W	30_S	0.715	0.76
381_K	385_F	0.715	0.76
397_M	441_I	0.713	0.76
120_F	160_L	0.713	0.76
226_Q	288_K	0.711	0.76
249_R	256_T	0.711	0.76
63_A	67_Y	0.710	0.76
275_P	344_D	0.710	0.76
96_K	101_E	0.709	0.76
125_G	277_D	0.709	0.76
95_V	98_A	0.708	0.75
47_N	80_I	0.707	0.75
287_K	365_Q	0.706	0.75
133_S	136_V	0.706	0.75
191_N	194_R	0.705	0.75
437_H	441_I	0.704	0.75
436_Q	440_E	0.703	0.75
214_D	248_D	0.703	0.75
187_N	206_R	0.702	0.75
403_P	409_F	0.698	0.74
23_S	26_T	0.694	0.74
16_E	58_Y	0.692	0.74
167_Y	336_D	0.690	0.74
148_F	265_F	0.689	0.73
186_T	189_F	0.689	0.73
257_L	262_R	0.687	0.73
12_L	16_E	0.687	0.73
146_P	233_F	0.686	0.73
128_F	269_L	0.684	0.73
216_I	265_F	0.683	0.73
359_I	393_L	0.682	0.73
7_L	66_I	0.682	0.73
182_S	217_Q	0.681	0.73
44_T	78_F	0.680	0.72
407_E	411_G	0.680	0.72
11_A	31_T	0.679	0.72
325_Y	337_L	0.678	0.72
240_S	245_I	0.676	0.72
324_A	328_L	0.676	0.72
199_V	203_N	0.675	0.72
155_L	312_I	0.673	0.72
358_E	445_L	0.673	0.72
98_A	103_T	0.672	0.72
284_I	312_I	0.672	0.72
202_R	232_T	0.672	0.72
371_L	374_F	0.670	0.71
112_N	162_H	0.669	0.71
141_A	401_S	0.668	0.71
161_M	214_D	0.668	0.71
125_G	273_I	0.667	0.71
397_M	442_K	0.664	0.71
185_F	232_T	0.663	0.71
277_D	280_T	0.662	0.70
149_I	271_T	0.662	0.70
115_Y	180_L	0.662	0.70
61_L	64_D	0.662	0.70
187_N	232_T	0.660	0.70
155_L	311_N	0.659	0.70
234_N	264_R	0.657	0.70
226_Q	257_L	0.655	0.70
7_L	11_A	0.654	0.70
134_L	138_E	0.650	0.69
360_Q	400_S	0.650	0.69
232_T	236_L	0.650	0.69
258_E	262_R	0.648	0.69
138_E	167_Y	0.648	0.69
38_G	101_E	0.647	0.69
243_I	341_A	0.646	0.69
188_E	342_L	0.646	0.69
204_R	216_I	0.645	0.68
218_F	227_E	0.645	0.68
435_Q	442_K	0.643	0.68
379_R	413_D	0.643	0.68
128_F	270_I	0.640	0.68
27_W	267_W	0.640	0.68
287_K	291_A	0.639	0.68
232_T	235_T	0.639	0.68
236_L	243_I	0.638	0.68
224_Q	227_E	0.636	0.67
10_Q	13_A	0.635	0.67
402_L	415_T	0.632	0.67
27_W	388_Q	0.632	0.67
46_P	80_I	0.632	0.67
122_I	127_R	0.631	0.67
7_L	10_Q	0.629	0.67
231_H	324_A	0.629	0.67
360_Q	394_S	0.628	0.66
136_V	272_D	0.627	0.66
124_S	271_T	0.627	0.66
385_F	424_I	0.627	0.66
182_S	383_V	0.625	0.66
98_A	102_D	0.620	0.65
29_K	133_S	0.619	0.65
216_I	246_S	0.619	0.65
415_T	419_H	0.619	0.65
268_G	414_H	0.617	0.65
10_Q	14_Q	0.616	0.65
189_F	196_N	0.615	0.65
167_Y	287_K	0.615	0.65
116_T	119_T	0.614	0.65
60_H	332_D	0.614	0.65
230_F	265_F	0.614	0.65
381_K	388_Q	0.614	0.65
185_F	206_R	0.613	0.65
380_T	384_A	0.612	0.64
438_V	442_K	0.611	0.64
146_P	234_N	0.610	0.64
362_V	365_Q	0.610	0.64
59_L	76_I	0.609	0.64
213_I	270_I	0.609	0.64
362_V	441_I	0.608	0.64
95_V	99_V	0.608	0.64
281_R	309_D	0.607	0.64
95_V	101_E	0.607	0.64
389_I	430_D	0.606	0.64
413_D	423_K	0.605	0.64
81_P	84_Q	0.605	0.64
258_E	263_S	0.605	0.64
182_S	213_I	0.605	0.64
398_T	402_L	0.604	0.63
183_E	231_H	0.602	0.63
226_Q	258_E	0.601	0.63
87_E	93_P	0.600	0.63
128_F	271_T	0.599	0.63
83_N	86_V	0.599	0.63
374_F	384_A	0.597	0.63
217_Q	260_R	0.596	0.62
218_F	228_E	0.596	0.62
136_V	146_P	0.595	0.62
100_K	105_D	0.595	0.62
64_D	68_E	0.594	0.62
419_H	423_K	0.594	0.62
393_L	397_M	0.594	0.62
165_G	246_S	0.594	0.62
232_T	280_T	0.594	0.62
297_P	332_D	0.592	0.62
358_E	361_R	0.592	0.62
389_I	424_I	0.587	0.61
96_K	103_T	0.586	0.61
100_K	103_T	0.586	0.61
250_P	270_I	0.586	0.61
388_Q	423_K	0.584	0.61
41_L	51_R	0.582	0.61
381_K	418_I	0.580	0.60
93_P	97_K	0.580	0.60
202_R	240_S	0.579	0.60
125_G	300_V	0.579	0.60
101_E	105_D	0.579	0.60
440_E	443_E	0.578	0.60
86_V	103_T	0.578	0.60
386_P	416_T	0.577	0.60
280_T	283_A	0.577	0.60
135_A	274_T	0.574	0.60
145_N	311_N	0.574	0.60
155_L	279_E	0.574	0.60
45_A	49_F	0.574	0.60
198_A	232_T	0.571	0.59
85_D	174_S	0.571	0.59
254_I	395_R	0.570	0.59
39_D	75_S	0.569	0.59
43_I	416_T	0.569	0.59
124_S	302_L	0.569	0.59
373_D	389_I	0.568	0.59
161_M	378_K	0.568	0.59
43_I	59_L	0.568	0.59
153_V	321_R	0.568	0.59
256_T	262_R	0.566	0.58
212_L	224_Q	0.566	0.58
401_S	417_V	0.565	0.58
381_K	428_L	0.564	0.58
314_E	342_L	0.564	0.58
385_F	389_I	0.564	0.58
27_W	226_Q	0.564	0.58
146_P	317_G	0.564	0.58
397_M	403_P	0.563	0.58
15_I	65_T	0.562	0.58
205_Y	233_F	0.561	0.58
355_T	358_E	0.561	0.58
373_D	382_S	0.560	0.58
99_V	104_S	0.560	0.58
139_A	142_K	0.559	0.58
354_I	398_T	0.559	0.58
34_H	79_V	0.558	0.57
55_E	63_A	0.558	0.57
237_H	320_I	0.558	0.57
380_T	386_P	0.558	0.57
395_R	403_P	0.556	0.57
237_H	245_I	0.555	0.57
95_V	106_F	0.554	0.57
217_Q	317_G	0.554	0.57
161_M	246_S	0.554	0.57
303_Y	307_Q	0.553	0.57
208_V	289_A	0.553	0.57
190_I	218_F	0.553	0.57
393_L	441_I	0.552	0.57
399_D	404_K	0.552	0.57
153_V	184_K	0.551	0.56
118_D	170_D	0.550	0.56
437_H	440_E	0.550	0.56
187_N	202_R	0.549	0.56
180_L	353_V	0.547	0.56
5_L	9_N	0.546	0.56
412_R	424_I	0.546	0.56
214_D	317_G	0.544	0.56
87_E	100_K	0.544	0.56
155_L	305_A	0.544	0.56
424_I	427_L	0.543	0.55
20_S	23_S	0.541	0.55
354_I	383_V	0.541	0.55
266_E	314_E	0.540	0.55
102_D	106_F	0.540	0.55
369_I	444_Q	0.540	0.55
17_K	73_E	0.539	0.55
201_F	261_L	0.539	0.55
66_I	70_T	0.537	0.55
111_L	285_L	0.536	0.54
162_H	165_G	0.534	0.54
361_R	404_K	0.534	0.54
135_A	272_D	0.533	0.54
265_F	284_I	0.532	0.54
179_Y	246_S	0.532	0.54
119_T	292_E	0.532	0.54
386_P	391_M	0.532	0.54
183_E	222_K	0.531	0.54
165_G	319_L	0.530	0.54
124_S	227_E	0.530	0.54
82_Q	98_A	0.529	0.53
357_K	361_R	0.529	0.53
15_I	19_L	0.529	0.53
202_R	206_R	0.529	0.53
304_I	342_L	0.528	0.53
293_G	371_L	0.528	0.53
85_D	93_P	0.528	0.53
299_E	335_A	0.528	0.53
386_P	389_I	0.527	0.53
275_P	311_N	0.527	0.53
189_F	202_R	0.526	0.53
86_V	93_P	0.526	0.53
391_M	419_H	0.524	0.53
217_Q	229_F	0.524	0.53
96_K	99_V	0.524	0.53
144_Y	231_H	0.523	0.53
102_D	107_P	0.522	0.53
108_Q	169_I	0.522	0.53
68_E	103_T	0.521	0.52
98_A	106_F	0.521	0.52
27_W	416_T	0.520	0.52
98_A	101_E	0.520	0.52
151_G	261_L	0.520	0.52
402_L	405_I	0.519	0.52
121_V	155_L	0.519	0.52
246_S	249_R	0.518	0.52
247_S	265_F	0.518	0.52
152_G	310_S	0.518	0.52
392_Y	421_H	0.518	0.52
220_A	249_R	0.518	0.52
362_V	366_Q	0.517	0.52
324_A	398_T	0.517	0.52
260_R	279_E	0.516	0.52
132_A	310_S	0.516	0.52
127_R	134_L	0.515	0.52
193_I	207_N	0.515	0.52
198_A	412_R	0.514	0.51
57_R	412_R	0.513	0.51
147_L	269_L	0.513	0.51
31_T	78_F	0.513	0.51
94_Q	98_A	0.513	0.51
182_S	246_S	0.512	0.51
325_Y	346_I	0.512	0.51
88_D	100_K	0.511	0.51
187_N	276_P	0.509	0.51
24_F	78_F	0.509	0.51
96_K	102_D	0.509	0.51
94_Q	101_E	0.508	0.51
184_K	254_I	0.508	0.51
158_T	260_R	0.507	0.50
113_P	244_V	0.506	0.50
94_Q	104_S	0.506	0.50
35_S	87_E	0.506	0.50
88_D	93_P	0.506	0.50
322_V	418_I	0.505	0.50
334_N	429_A	0.505	0.50
351_P	354_I	0.505	0.50
281_R	285_L	0.505	0.50
358_E	362_V	0.504	0.50
186_T	202_R	0.504	0.50
354_I	359_I	0.503	0.50
369_I	383_V	0.500	0.49

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2z4sA	1	0.5359	100	0.376	Contact Map
1l8qA	1	0.7085	100	0.573	Contact Map
3nbxX	1	0.7175	100	0.652	Contact Map
3bosA	2	0.5157	100	0.758	Contact Map
2qgzA	1	0.3857	100	0.777	Contact Map
1j1vA	1	0.2085	100	0.779	Contact Map
4w5wA	1	0.5291	100	0.781	Contact Map
3pvvA	1	0.2063	100	0.784	Contact Map
2r44A	1	0.5964	100	0.814	Contact Map
3u61B	3	0.6861	100	0.823	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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