GREMLIN Database
RL34 - 50S ribosomal protein L34
UniProt: P05647 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 44 (43)
Sequences: 188 (39)
Seq/√Len: 5.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
8_N11_K3.7510.91
8_N14_K3.3480.85
10_R14_K2.6680.68
11_K15_V1.8010.38
9_N13_S1.7370.36
15_V20_S1.6780.34
3_R6_Q1.6350.33
5_F12_R1.6260.33
36_R41_V1.5410.30
8_N15_V1.5090.29
15_V43_S1.4880.29
5_F9_N1.3410.25
26_N30_V1.3240.24
25_K29_L1.2360.22
13_S41_V1.2280.22
29_L36_R1.1430.20
23_S33_R1.0910.19
11_K20_S1.0820.19
12_R19_R1.0640.18
31_L40_K1.0180.17
30_V33_R0.9560.16
6_Q33_R0.9370.16
5_F33_R0.9260.15
36_R40_K0.9170.15
32_A43_S0.8920.15
9_N29_L0.8800.15
2_K6_Q0.8580.14
15_V30_V0.8570.14
6_Q42_L0.8490.14
33_R36_R0.8370.14
20_S23_S0.8330.14
2_K11_K0.8290.14
29_L32_A0.8150.14
8_N23_S0.8110.13
13_S24_S0.8070.13
29_L33_R0.7950.13
26_N32_A0.7860.13
19_R32_A0.7300.12
25_K36_R0.6950.12
23_S29_L0.6920.12
26_N41_V0.6890.12
23_S36_R0.6780.11
9_N32_A0.6710.11
2_K42_L0.6680.11
14_K20_S0.6570.11
3_R11_K0.6270.11
8_N19_R0.6250.11
20_S32_A0.6240.11
3_R8_N0.6140.11
31_L38_G0.6090.10
20_S33_R0.6040.10
20_S29_L0.5700.10
2_K8_N0.5560.10
19_R36_R0.5530.10
15_V32_A0.5420.10
26_N29_L0.5390.10
5_F14_K0.5370.10
4_T30_V0.5350.10
4_T37_K0.5300.09
23_S40_K0.5250.09
15_V19_R0.5150.09
12_R15_V0.5100.09
14_K31_L0.5070.09
2_K25_K0.5000.09
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4tp92 1 1 99.8 0.107 Contact Map
4rb67 1 1 99.8 0.107 Contact Map
3j3w2 1 1 99.8 0.113 Contact Map
1vw4Y 1 1 99.8 0.128 Contact Map
3j7y2 1 0.9773 99.7 0.135 Contact Map
3bbo4 1 0.7727 99.6 0.208 Contact Map
4ujqD 1 0.3864 2.2 0.912 Contact Map
2k3yA 1 0.4091 2.1 0.913 Contact Map
2jpjA 1 0.3636 1.8 0.916 Contact Map
3ed3A 1 0.2045 1.6 0.918 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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