DNAG - BACSU - GREMLIN Contacts

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DNAG - DNA primase

UniProt:	P05096	Sequences: MGNRIPDEIVDQVQKSADIVEVIGDYVQLKKQGRNYFGLCPFHGESTPSFSVSPDKQIFHCFGCGAGGNVFSFLRQMEGYSFAESVSHLADKYQIDFPDDITVHSGARPESSGEQKMAEAHELLKKFYHHLLINTKEGQEALDYLLSRGFTKELINEFQIGYALDSWDFITKFLVKRGFSEAQMEKAGLLIRREDGSGYFDRFRNRVMFPIHDHHGAVVAFSGRALGSQQPKYMNSPETPLFHKSKLLYNFYKARLHIRKQERAVLFEGFADVISAVSSDVKESIATMGTSLTDDHVKILRRNVEEIILCYDSDKAGYEATLKASELLQKKGCKVRVAMIPDGLDPDDYIKKFGGEKFKNDIIDASVTVMAFKMQYFRKGKNLSDEGDRLAYIKDVLKEISTLSGSLEQEVYVKQLASEFSLSQESLTEQLSVFSKQNKPADNSGETKTRRAHLTTKARQKRLRPAYENAERLLLAHMLRDRSVIKKVIDRVGFQFNIDEHRALAAYLYAFYEEGAELTPQHLMARVTDDHISQLLSDILMLQVNQELSEAELSDYVKKVLNQRNWSMIKEKEAERAEAERQKDFLRAASLAQEIVTLNRSLK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	603 (575)
Sequences:	3921 (2928)
Seq/√Len:	122.1

ECOLI - DNAG
BACSU - DNAG

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
66_A	76_Q	5.330	1.00
191_I	202_R	3.558	1.00
213_D	217_A	3.516	1.00
32_Q	37_F	3.474	1.00
219_V	247_L	3.434	1.00
168_D	172_K	3.316	1.00
222_S	270_F	3.174	1.00
344_L	348_D	3.116	1.00
121_H	241_L	3.091	1.00
139_Q	143_D	2.982	1.00
37_F	51_S	2.921	1.00
113_G	186_K	2.904	1.00
344_L	352_K	2.886	1.00
127_F	169_F	2.876	1.00
40_C	64_C	2.873	1.00
45_E	63_G	2.861	1.00
25_D	92_K	2.852	1.00
146_L	152_K	2.826	1.00
40_C	43_H	2.788	1.00
59_F	76_Q	2.743	1.00
43_H	64_C	2.647	1.00
12_Q	16_S	2.624	1.00
17_A	93_Y	2.518	1.00
60_H	65_G	2.492	1.00
124_L	189_L	2.473	1.00
116_K	183_Q	2.463	1.00
166_S	169_F	2.461	1.00
186_K	240_P	2.437	1.00
367_V	375_Q	2.436	1.00
20_V	36_Y	2.431	1.00
145_L	207_V	2.424	1.00
306_E	334_K	2.422	1.00
87_S	99_D	2.421	1.00
154_L	278_S	2.406	1.00
117_M	241_L	2.404	1.00
125_K	159_Q	2.396	1.00
17_A	22_V	2.339	1.00
157_E	282_K	2.322	1.00
143_D	147_S	2.314	1.00
162_Y	205_N	2.310	1.00
263_R	283_E	2.274	1.00
212_H	252_Y	2.258	1.00
264_A	300_L	2.238	1.00
29_L	52_V	2.227	1.00
125_K	218_V	2.211	1.00
385_D	388_D	2.195	1.00
80_Y	88_H	2.185	1.00
287_T	311_Y	2.183	1.00
257_H	282_K	2.181	1.00
315_K	319_E	2.146	1.00
40_C	63_G	2.124	1.00
222_S	288_M	2.121	1.00
45_E	50_F	2.116	1.00
246_K	295_D	2.102	1.00
171_T	190_L	2.081	1.00
27_V	38_G	2.062	1.00
182_A	186_K	2.045	1.00
34_R	55_D	2.033	1.00
129_H	159_Q	2.031	1.00
81_S	84_E	2.017	1.00
124_L	170_I	1.997	1.00
209_F	249_Y	1.986	1.00
371_A	415_Q	1.973	1.00
141_A	207_V	1.956	1.00
308_I	338_A	1.941	1.00
43_H	63_G	1.940	1.00
212_H	253_K	1.932	1.00
225_A	229_Q	1.931	1.00
22_V	70_V	1.930	1.00
355_G	359_K	1.921	1.00
258_I	264_A	1.884	1.00
263_R	306_E	1.872	1.00
152_K	156_N	1.856	1.00
349_Y	353_F	1.851	1.00
123_L	179_F	1.846	1.00
150_F	271_A	1.843	1.00
175_V	181_E	1.837	1.00
151_T	154_L	1.816	1.00
231_P	234_M	1.813	1.00
185_E	192_R	1.809	1.00
378_R	419_E	1.787	1.00
306_E	336_R	1.783	1.00
152_K	155_I	1.783	1.00
165_D	205_N	1.777	1.00
82_F	86_V	1.774	1.00
220_A	236_S	1.773	1.00
587_R	590_S	1.767	1.00
18_D	54_P	1.760	1.00
9_I	13_V	1.758	1.00
35_N	53_S	1.758	1.00
53_S	56_K	1.748	1.00
140_E	205_N	1.734	1.00
319_E	323_K	1.730	1.00
72_S	76_Q	1.725	1.00
287_T	296_H	1.724	1.00
78_E	88_H	1.719	1.00
123_L	177_R	1.714	1.00
180_S	183_Q	1.711	1.00
60_H	67_G	1.710	1.00
26_Y	78_E	1.700	1.00
125_K	129_H	1.697	1.00
359_K	364_D	1.696	1.00
184_M	190_L	1.682	1.00
35_N	51_S	1.658	1.00
380_G	395_D	1.658	1.00
14_Q	69_N	1.647	1.00
225_A	230_Q	1.646	1.00
487_K	550_E	1.641	1.00
242_F	288_M	1.639	1.00
13_V	86_V	1.638	1.00
356_E	360_N	1.637	1.00
131_L	164_L	1.619	1.00
38_G	52_V	1.617	1.00
26_Y	77_M	1.602	1.00
59_F	66_A	1.600	1.00
159_Q	212_H	1.590	1.00
9_I	98_P	1.587	1.00
157_E	253_K	1.587	1.00
142_L	152_K	1.580	1.00
415_Q	418_S	1.577	1.00
584_D	587_R	1.572	1.00
313_S	344_L	1.564	1.00
129_H	156_N	1.558	1.00
238_E	243_H	1.556	1.00
117_M	187_A	1.554	1.00
69_N	72_S	1.543	1.00
142_L	146_L	1.537	1.00
17_A	70_V	1.531	1.00
155_I	160_I	1.527	1.00
374_M	396_V	1.527	1.00
187_A	190_L	1.522	1.00
121_H	220_A	1.514	1.00
47_T	50_F	1.501	1.00
568_M	571_E	1.499	1.00
118_A	217_A	1.491	1.00
151_T	278_S	1.485	1.00
14_Q	70_V	1.472	1.00
413_V	427_L	1.467	1.00
397_L	431_L	1.464	1.00
167_W	204_R	1.463	1.00
267_F	284_S	1.462	1.00
10_V	86_V	1.450	1.00
381_K	395_D	1.448	1.00
61_C	64_C	1.444	1.00
122_E	159_Q	1.440	1.00
167_W	200_F	1.438	1.00
336_R	366_S	1.438	1.00
47_T	63_G	1.429	1.00
297_V	327_L	1.418	1.00
142_L	155_I	1.417	1.00
18_D	21_E	1.413	1.00
132_L	145_L	1.412	1.00
40_C	61_C	1.408	1.00
14_Q	71_F	1.406	1.00
236_S	239_T	1.405	1.00
74_L	88_H	1.405	1.00
121_H	187_A	1.404	1.00
7_D	11_D	1.399	1.00
50_F	63_G	1.388	1.00
11_D	15_K	1.387	1.00
360_N	365_A	1.373	1.00
202_R	237_P	1.373	1.00
138_G	142_L	1.372	1.00
118_A	241_L	1.372	1.00
338_A	362_I	1.368	1.00
53_S	58_I	1.363	1.00
171_T	181_E	1.345	1.00
267_F	276_A	1.321	1.00
200_F	204_R	1.319	1.00
133_I	142_L	1.309	1.00
354_G	357_K	1.309	1.00
245_S	295_D	1.306	1.00
360_N	364_D	1.301	1.00
127_F	131_L	1.289	1.00
153_E	156_N	1.285	1.00
163_A	208_M	1.285	1.00
310_C	358_F	1.284	1.00
173_F	177_R	1.280	1.00
187_A	239_T	1.271	1.00
250_N	277_V	1.267	1.00
297_V	328_L	1.264	1.00
133_I	152_K	1.263	1.00
146_L	155_I	1.259	1.00
116_K	119_E	1.258	1.00
13_V	95_I	1.257	1.00
9_I	95_I	1.253	0.99
43_H	61_C	1.246	0.99
414_K	424_Q	1.234	0.99
29_L	38_G	1.234	0.99
136_K	139_Q	1.229	0.99
243_H	246_K	1.227	0.99
350_I	358_F	1.227	0.99
60_H	66_A	1.222	0.99
340_I	362_I	1.220	0.99
185_E	199_Y	1.219	0.99
122_E	126_K	1.217	0.99
145_L	155_I	1.214	0.99
325_S	369_V	1.211	0.99
17_A	89_L	1.207	0.99
310_C	340_I	1.207	0.99
46_S	63_G	1.204	0.99
551_A	555_D	1.203	0.99
281_V	359_K	1.203	0.99
127_F	164_L	1.199	0.99
115_Q	119_E	1.199	0.99
171_T	175_V	1.197	0.99
179_F	184_M	1.197	0.99
525_A	528_T	1.193	0.99
586_L	589_A	1.192	0.99
270_F	288_M	1.192	0.99
35_N	58_I	1.191	0.99
17_A	92_K	1.189	0.99
87_S	91_D	1.183	0.99
245_S	296_H	1.179	0.99
570_K	573_E	1.178	0.99
20_V	54_P	1.177	0.99
19_I	22_V	1.167	0.99
190_L	199_Y	1.167	0.99
121_H	236_S	1.163	0.99
6_P	98_P	1.160	0.99
391_A	395_D	1.159	0.99
16_S	95_I	1.156	0.99
129_H	133_I	1.155	0.99
174_L	184_M	1.154	0.99
172_K	176_K	1.151	0.99
276_A	350_I	1.150	0.99
193_R	200_F	1.148	0.99
9_I	97_F	1.145	0.99
185_E	190_L	1.143	0.99
502_R	506_A	1.142	0.99
74_L	80_Y	1.142	0.99
322_L	373_K	1.139	0.99
135_T	138_G	1.137	0.99
83_A	87_S	1.130	0.99
160_I	274_I	1.127	0.99
566_W	570_K	1.125	0.99
247_L	288_M	1.124	0.99
262_E	305_E	1.123	0.99
120_A	183_Q	1.119	0.99
89_L	92_K	1.119	0.99
261_Q	359_K	1.119	0.99
139_Q	142_L	1.108	0.99
279_S	355_G	1.106	0.99
344_L	353_F	1.105	0.99
12_Q	15_K	1.105	0.99
80_Y	85_S	1.104	0.99
158_F	277_V	1.102	0.99
545_N	548_L	1.100	0.99
250_N	273_V	1.098	0.99
60_H	63_G	1.093	0.99
281_V	350_I	1.093	0.99
250_N	253_K	1.092	0.99
122_E	217_A	1.089	0.99
225_A	231_P	1.087	0.99
211_I	222_S	1.086	0.99
26_Y	73_F	1.085	0.99
559_K	562_N	1.082	0.99
150_F	155_I	1.080	0.98
18_D	57_Q	1.078	0.98
32_Q	51_S	1.076	0.98
409_Q	413_V	1.075	0.98
138_G	141_A	1.067	0.98
581_R	584_D	1.066	0.98
71_F	86_V	1.061	0.98
39_L	45_E	1.061	0.98
106_G	109_P	1.059	0.98
212_H	218_V	1.054	0.98
121_H	128_Y	1.047	0.98
145_L	160_I	1.046	0.98
474_L	553_L	1.046	0.98
150_F	209_F	1.044	0.98
555_D	559_K	1.040	0.98
23_I	27_V	1.040	0.98
301_R	333_C	1.040	0.98
192_R	199_Y	1.040	0.98
59_F	67_G	1.039	0.98
415_Q	419_E	1.038	0.98
123_L	173_F	1.036	0.98
202_R	234_M	1.036	0.98
307_I	328_L	1.033	0.98
423_S	426_S	1.028	0.98
285_I	300_L	1.028	0.98
143_D	146_L	1.027	0.98
193_R	197_S	1.026	0.98
305_E	333_C	1.025	0.98
574_A	578_E	1.024	0.98
356_E	359_K	1.017	0.98
328_L	335_V	1.017	0.98
123_L	126_K	1.015	0.98
590_S	593_Q	1.014	0.98
17_A	21_E	1.009	0.98
347_D	351_K	1.009	0.98
276_A	358_F	1.007	0.98
208_M	223_G	1.006	0.98
29_L	33_G	1.000	0.98
291_S	323_K	0.997	0.97
575_E	587_R	0.996	0.97
381_K	388_D	0.995	0.97
203_F	208_M	0.993	0.97
311_Y	324_A	0.991	0.97
382_N	385_D	0.990	0.97
57_Q	70_V	0.989	0.97
88_H	92_K	0.988	0.97
579_A	584_D	0.987	0.97
120_A	179_F	0.987	0.97
40_C	66_A	0.987	0.97
491_R	561_L	0.985	0.97
58_I	67_G	0.984	0.97
19_I	59_F	0.984	0.97
191_I	200_F	0.983	0.97
523_L	527_V	0.981	0.97
569_I	573_E	0.979	0.97
571_E	575_E	0.978	0.97
283_E	359_K	0.977	0.97
13_V	71_F	0.976	0.97
182_A	185_E	0.976	0.97
225_A	228_S	0.975	0.97
292_L	297_V	0.974	0.97
46_S	50_F	0.973	0.97
589_A	593_Q	0.971	0.97
382_N	388_D	0.970	0.97
140_E	143_D	0.968	0.97
138_G	207_V	0.962	0.97
17_A	74_L	0.961	0.97
36_Y	54_P	0.953	0.97
35_N	56_K	0.952	0.97
71_F	89_L	0.949	0.97
162_Y	226_L	0.948	0.97
378_R	392_Y	0.948	0.97
586_L	590_S	0.948	0.97
245_S	293_T	0.947	0.97
287_T	309_L	0.945	0.96
573_E	577_A	0.945	0.96
234_M	242_F	0.945	0.96
133_I	156_N	0.940	0.96
287_T	324_A	0.934	0.96
263_R	364_D	0.934	0.96
24_G	28_Q	0.933	0.96
11_D	14_Q	0.932	0.96
265_V	281_V	0.931	0.96
292_L	324_A	0.931	0.96
570_K	574_A	0.928	0.96
5_I	83_A	0.926	0.96
174_L	179_F	0.925	0.96
120_A	187_A	0.925	0.96
585_F	588_A	0.925	0.96
149_G	351_K	0.919	0.96
188_G	237_P	0.918	0.96
44_G	63_G	0.912	0.96
353_F	357_K	0.912	0.96
568_M	572_K	0.911	0.96
181_E	199_Y	0.910	0.96
39_L	47_T	0.909	0.96
257_H	261_Q	0.907	0.96
273_V	284_S	0.903	0.95
553_L	557_V	0.902	0.95
120_A	124_L	0.900	0.95
124_L	128_Y	0.899	0.95
357_K	360_N	0.898	0.95
84_E	87_S	0.897	0.95
51_S	58_I	0.897	0.95
227_G	231_P	0.893	0.95
39_L	46_S	0.892	0.95
74_L	77_M	0.891	0.95
424_Q	428_T	0.889	0.95
5_I	10_V	0.884	0.95
133_I	155_I	0.883	0.95
38_G	50_F	0.877	0.95
26_Y	88_H	0.877	0.95
349_Y	358_F	0.876	0.95
471_E	501_H	0.874	0.95
386_E	411_V	0.873	0.95
183_Q	186_K	0.871	0.94
39_L	63_G	0.870	0.94
265_V	363_I	0.870	0.94
191_I	234_M	0.868	0.94
251_F	303_N	0.860	0.94
313_S	343_G	0.859	0.94
375_Q	419_E	0.856	0.94
275_S	279_S	0.855	0.94
249_Y	270_F	0.854	0.94
128_Y	170_I	0.852	0.94
164_L	169_F	0.852	0.94
583_K	588_A	0.852	0.94
498_I	501_H	0.851	0.94
266_L	309_L	0.850	0.94
12_Q	95_I	0.845	0.94
193_R	196_G	0.845	0.94
5_I	9_I	0.845	0.94
222_S	234_M	0.845	0.94
205_N	227_G	0.844	0.94
413_V	428_T	0.840	0.93
265_V	276_A	0.840	0.93
128_Y	169_F	0.839	0.93
223_G	270_F	0.836	0.93
13_V	17_A	0.836	0.93
167_W	193_R	0.836	0.93
88_H	91_D	0.834	0.93
39_L	50_F	0.834	0.93
530_D	533_S	0.834	0.93
520_P	523_L	0.831	0.93
181_E	192_R	0.830	0.93
296_H	311_Y	0.827	0.93
475_L	505_A	0.827	0.93
119_E	123_L	0.827	0.93
263_R	308_I	0.826	0.93
301_R	305_E	0.823	0.93
425_E	428_T	0.823	0.93
155_I	207_V	0.822	0.93
170_I	174_L	0.821	0.93
192_R	196_G	0.821	0.93
79_G	259_R	0.821	0.93
72_S	75_R	0.819	0.92
125_K	208_M	0.817	0.92
76_Q	79_G	0.811	0.92
127_F	173_F	0.811	0.92
387_G	391_A	0.810	0.92
318_Y	339_M	0.809	0.92
181_E	185_E	0.809	0.92
277_V	282_K	0.808	0.92
505_A	509_Y	0.808	0.92
489_I	513_E	0.806	0.92
220_A	247_L	0.806	0.92
574_A	577_A	0.806	0.92
579_A	583_K	0.806	0.92
153_E	157_E	0.806	0.92
377_F	396_V	0.805	0.92
567_S	571_E	0.803	0.92
396_V	416_L	0.803	0.92
141_A	145_L	0.801	0.92
184_M	187_A	0.799	0.92
519_T	522_H	0.798	0.91
550_E	554_S	0.798	0.91
131_L	135_T	0.798	0.91
273_V	313_S	0.795	0.91
430_Q	433_V	0.795	0.91
8_E	12_Q	0.793	0.91
168_D	171_T	0.793	0.91
300_L	333_C	0.792	0.91
216_G	252_Y	0.791	0.91
157_E	277_V	0.791	0.91
263_R	304_V	0.790	0.91
313_S	341_P	0.790	0.91
414_K	418_S	0.788	0.91
528_T	533_S	0.788	0.91
422_L	427_L	0.788	0.91
90_A	93_Y	0.787	0.91
348_D	351_K	0.786	0.91
9_I	12_Q	0.786	0.91
342_D	353_F	0.782	0.91
587_R	591_L	0.782	0.91
242_F	296_H	0.781	0.91
167_W	195_D	0.779	0.90
417_A	427_L	0.779	0.90
28_Q	39_L	0.778	0.90
37_F	58_I	0.775	0.90
367_V	371_A	0.775	0.90
243_H	295_D	0.773	0.90
417_A	422_L	0.772	0.90
519_T	523_L	0.769	0.90
43_H	66_A	0.769	0.90
37_F	48_P	0.767	0.90
567_S	570_K	0.762	0.89
91_D	96_D	0.762	0.89
397_L	413_V	0.761	0.89
403_L	412_Y	0.758	0.89
262_E	306_E	0.758	0.89
340_I	344_L	0.755	0.89
209_F	271_A	0.755	0.89
477_H	553_L	0.750	0.89
410_E	423_S	0.749	0.89
263_R	359_K	0.748	0.89
291_S	321_T	0.747	0.89
534_Q	538_D	0.746	0.88
506_A	510_A	0.746	0.88
5_I	97_F	0.744	0.88
583_K	586_L	0.743	0.88
5_I	86_V	0.742	0.88
578_E	582_Q	0.742	0.88
432_S	435_S	0.741	0.88
30_K	33_G	0.741	0.88
321_T	339_M	0.740	0.88
287_T	291_S	0.740	0.88
220_A	243_H	0.738	0.88
90_A	97_F	0.738	0.88
377_F	395_D	0.737	0.88
322_L	376_Y	0.736	0.88
292_L	311_Y	0.732	0.88
413_V	417_A	0.728	0.87
158_F	249_Y	0.728	0.87
341_P	344_L	0.725	0.87
277_V	284_S	0.724	0.87
265_V	310_C	0.724	0.87
38_G	77_M	0.724	0.87
338_A	363_I	0.721	0.87
128_Y	163_A	0.721	0.87
211_I	247_L	0.720	0.87
588_A	592_A	0.718	0.87
294_D	327_L	0.715	0.86
326_E	402_T	0.715	0.86
473_L	552_E	0.714	0.86
115_Q	217_A	0.711	0.86
23_I	77_M	0.711	0.86
163_A	205_N	0.711	0.86
294_D	330_K	0.709	0.86
299_I	303_N	0.707	0.86
571_E	574_A	0.707	0.86
376_Y	379_K	0.707	0.86
188_G	202_R	0.704	0.85
222_S	250_N	0.704	0.85
258_I	304_V	0.703	0.85
363_I	366_S	0.703	0.85
502_R	505_A	0.702	0.85
510_A	514_E	0.701	0.85
292_L	309_L	0.700	0.85
299_I	302_R	0.700	0.85
211_I	220_A	0.699	0.85
430_Q	434_F	0.699	0.85
368_T	371_A	0.698	0.85
373_K	399_E	0.697	0.85
397_L	434_F	0.697	0.85
297_V	333_C	0.696	0.85
250_N	288_M	0.696	0.85
572_K	576_R	0.694	0.85
471_E	496_F	0.694	0.85
261_Q	282_K	0.694	0.85
108_R	112_S	0.693	0.85
267_F	273_V	0.691	0.84
309_L	337_V	0.690	0.84
10_V	13_V	0.690	0.84
109_P	113_G	0.688	0.84
124_L	201_D	0.686	0.84
81_S	88_H	0.685	0.84
471_E	498_I	0.685	0.84
207_V	226_L	0.685	0.84
572_K	575_E	0.682	0.84
580_E	583_K	0.682	0.84
576_R	591_L	0.681	0.84
406_S	409_Q	0.680	0.83
18_D	36_Y	0.678	0.83
281_V	363_I	0.678	0.83
529_D	533_S	0.678	0.83
546_Q	549_S	0.678	0.83
588_A	591_L	0.677	0.83
413_V	431_L	0.677	0.83
301_R	331_K	0.676	0.83
326_E	373_K	0.676	0.83
59_F	72_S	0.676	0.83
170_I	189_L	0.675	0.83
23_I	52_V	0.675	0.83
5_I	17_A	0.673	0.83
392_Y	420_F	0.673	0.83
576_R	580_E	0.673	0.83
279_S	350_I	0.671	0.83
37_F	47_T	0.669	0.82
386_E	390_L	0.668	0.82
203_F	234_M	0.668	0.82
300_L	307_I	0.664	0.82
313_S	362_I	0.663	0.82
411_V	414_K	0.662	0.82
581_R	588_A	0.661	0.82
411_V	415_Q	0.661	0.82
413_V	424_Q	0.660	0.82
383_L	388_D	0.660	0.82
20_V	57_Q	0.658	0.81
568_M	587_R	0.658	0.81
69_N	75_R	0.658	0.81
578_E	581_R	0.657	0.81
389_R	411_V	0.656	0.81
125_K	221_F	0.656	0.81
276_A	284_S	0.655	0.81
434_F	437_Q	0.655	0.81
296_H	299_I	0.653	0.81
465_P	468_E	0.653	0.81
123_L	174_L	0.651	0.81
410_E	426_S	0.651	0.81
318_Y	376_Y	0.651	0.81
308_I	363_I	0.648	0.80
261_Q	283_E	0.648	0.80
265_V	308_I	0.647	0.80
23_I	70_V	0.646	0.80
201_D	204_R	0.646	0.80
45_E	60_H	0.646	0.80
535_L	538_D	0.644	0.80
391_A	394_K	0.643	0.80
275_S	278_S	0.643	0.80
262_E	304_V	0.642	0.80
410_E	428_T	0.642	0.80
126_K	159_Q	0.642	0.80
117_M	121_H	0.642	0.80
336_R	385_D	0.641	0.80
323_K	326_E	0.639	0.79
181_E	190_L	0.639	0.79
142_L	207_V	0.638	0.79
579_A	588_A	0.637	0.79
120_A	123_L	0.636	0.79
470_A	474_L	0.635	0.79
25_D	38_G	0.634	0.79
111_S	115_Q	0.631	0.79
353_F	360_N	0.630	0.79
167_W	201_D	0.629	0.78
426_S	430_Q	0.628	0.78
309_L	328_L	0.627	0.78
28_Q	38_G	0.627	0.78
242_F	247_L	0.627	0.78
24_G	319_E	0.626	0.78
329_Q	402_T	0.625	0.78
403_L	408_E	0.624	0.78
266_L	311_Y	0.623	0.78
220_A	250_N	0.623	0.78
479_L	508_L	0.623	0.78
112_S	116_K	0.622	0.78
339_M	375_Q	0.622	0.78
395_D	398_K	0.621	0.78
313_S	346_P	0.620	0.77
22_V	73_F	0.620	0.77
181_E	184_M	0.619	0.77
487_K	554_S	0.618	0.77
51_S	60_H	0.615	0.77
310_C	338_A	0.615	0.77
31_K	36_Y	0.615	0.77
441_A	446_E	0.615	0.77
249_Y	273_V	0.614	0.77
274_I	350_I	0.614	0.77
552_E	555_D	0.614	0.77
445_G	448_K	0.614	0.77
21_E	39_L	0.613	0.77
113_G	240_P	0.613	0.77
257_H	260_K	0.612	0.77
246_K	321_T	0.612	0.77
291_S	309_L	0.611	0.76
55_D	259_R	0.610	0.76
22_V	89_L	0.610	0.76
227_G	230_Q	0.610	0.76
167_W	191_I	0.610	0.76
409_Q	435_S	0.610	0.76
131_L	169_F	0.610	0.76
581_R	585_F	0.609	0.76
264_A	304_V	0.609	0.76
580_E	588_A	0.609	0.76
171_T	199_Y	0.608	0.76
471_E	497_N	0.608	0.76
441_A	444_S	0.608	0.76
392_Y	395_D	0.607	0.76
475_L	504_L	0.606	0.76
120_A	189_L	0.606	0.76
576_R	579_A	0.606	0.76
23_I	38_G	0.605	0.76
126_K	129_H	0.605	0.76
536_L	540_L	0.604	0.76
440_P	443_N	0.604	0.76
51_S	69_N	0.604	0.76
75_R	83_A	0.604	0.76
63_G	66_A	0.604	0.76
45_E	49_S	0.599	0.75
7_D	14_Q	0.595	0.74
163_A	242_F	0.594	0.74
20_V	24_G	0.593	0.74
179_F	187_A	0.593	0.74
160_I	270_F	0.593	0.74
575_E	579_A	0.593	0.74
147_S	207_V	0.592	0.74
28_Q	57_Q	0.592	0.74
575_E	578_E	0.592	0.74
408_E	411_V	0.592	0.74
211_I	288_M	0.591	0.74
548_L	551_A	0.591	0.74
576_R	581_R	0.591	0.74
13_V	70_V	0.590	0.74
6_P	10_V	0.589	0.74
321_T	325_S	0.589	0.74
468_E	501_H	0.589	0.74
247_L	251_F	0.588	0.74
128_Y	201_D	0.586	0.73
209_F	274_I	0.585	0.73
504_L	532_I	0.585	0.73
468_E	498_I	0.585	0.73
406_S	410_E	0.585	0.73
51_S	67_G	0.585	0.73
74_L	78_E	0.584	0.73
6_P	9_I	0.583	0.73
523_L	526_R	0.583	0.73
329_Q	337_V	0.583	0.73
187_A	236_S	0.582	0.73
175_V	184_M	0.582	0.73
577_A	581_R	0.581	0.73
81_S	476_A	0.580	0.73
377_F	399_E	0.580	0.73
511_F	523_L	0.580	0.73
166_S	205_N	0.579	0.72
211_I	231_P	0.578	0.72
5_I	100_D	0.577	0.72
401_S	434_F	0.576	0.72
156_N	159_Q	0.576	0.72
75_R	80_Y	0.575	0.72
393_I	427_L	0.573	0.72
175_V	178_G	0.572	0.72
371_A	375_Q	0.572	0.72
150_F	154_L	0.571	0.71
256_L	260_K	0.568	0.71
211_I	270_F	0.568	0.71
474_L	556_Y	0.568	0.71
183_Q	187_A	0.568	0.71
116_K	180_S	0.568	0.71
579_A	582_Q	0.567	0.71
370_M	387_G	0.567	0.71
432_S	436_K	0.566	0.71
107_A	110_E	0.566	0.71
368_T	403_L	0.566	0.71
276_A	310_C	0.566	0.71
545_N	549_S	0.565	0.71
275_S	351_K	0.565	0.71
350_I	354_G	0.564	0.71
534_Q	537_S	0.562	0.70
267_F	281_V	0.562	0.70
524_M	527_V	0.562	0.70
121_H	190_L	0.561	0.70
275_S	350_I	0.560	0.70
51_S	59_F	0.560	0.70
343_G	348_D	0.560	0.70
8_E	11_D	0.559	0.70
401_S	409_Q	0.559	0.70
381_K	392_Y	0.559	0.70
71_F	77_M	0.558	0.70
187_A	199_Y	0.558	0.70
109_P	112_S	0.558	0.70
478_M	508_L	0.557	0.70
7_D	10_V	0.555	0.69
202_R	236_S	0.555	0.69
557_V	561_L	0.554	0.69
572_K	591_L	0.554	0.69
23_I	59_F	0.554	0.69
167_W	194_E	0.554	0.69
271_A	347_D	0.553	0.69
377_F	392_Y	0.553	0.69
214_H	255_R	0.553	0.69
126_K	177_R	0.552	0.69
562_N	566_W	0.552	0.69
386_E	408_E	0.550	0.69
263_R	366_S	0.550	0.69
209_F	273_V	0.549	0.68
522_H	525_A	0.548	0.68
250_N	270_F	0.546	0.68
190_L	202_R	0.545	0.68
478_M	488_V	0.545	0.68
19_I	35_N	0.544	0.68
520_P	524_M	0.544	0.68
203_F	236_S	0.544	0.68
154_L	157_E	0.543	0.68
585_F	589_A	0.542	0.68
249_Y	271_A	0.540	0.67
273_V	277_V	0.540	0.67
261_Q	304_V	0.540	0.67
548_L	556_Y	0.540	0.67
294_D	298_K	0.539	0.67
6_P	241_L	0.538	0.67
132_L	160_I	0.537	0.67
470_A	556_Y	0.537	0.67
120_A	174_L	0.537	0.67
258_I	262_E	0.536	0.67
125_K	212_H	0.536	0.67
527_V	532_I	0.535	0.67
163_A	204_R	0.535	0.67
208_M	221_F	0.535	0.67
214_H	303_N	0.535	0.67
39_L	44_G	0.533	0.66
485_I	509_Y	0.532	0.66
290_T	313_S	0.532	0.66
13_V	90_A	0.532	0.66
162_Y	207_V	0.531	0.66
45_E	66_A	0.530	0.66
520_P	540_L	0.530	0.66
226_L	275_S	0.530	0.66
504_L	508_L	0.528	0.66
78_E	255_R	0.528	0.66
573_E	576_R	0.528	0.66
408_E	412_Y	0.527	0.65
250_N	267_F	0.527	0.65
162_Y	227_G	0.527	0.65
60_H	74_L	0.526	0.65
478_M	485_I	0.526	0.65
20_V	53_S	0.526	0.65
47_T	266_L	0.526	0.65
265_V	283_E	0.526	0.65
51_S	56_K	0.526	0.65
19_I	40_C	0.525	0.65
322_L	377_F	0.525	0.65
79_G	274_I	0.524	0.65
253_K	277_V	0.524	0.65
442_D	447_T	0.523	0.65
160_I	207_V	0.523	0.65
551_A	554_S	0.523	0.65
160_I	209_F	0.522	0.65
577_A	580_E	0.522	0.65
394_K	430_Q	0.522	0.65
410_E	424_Q	0.521	0.65
313_S	339_M	0.521	0.65
165_D	204_R	0.521	0.65
114_E	240_P	0.520	0.64
533_S	544_V	0.520	0.64
429_E	432_S	0.520	0.64
193_R	199_Y	0.520	0.64
189_L	208_M	0.519	0.64
393_I	407_L	0.518	0.64
584_D	593_Q	0.518	0.64
256_L	259_R	0.517	0.64
572_K	584_D	0.517	0.64
400_I	409_Q	0.517	0.64
106_G	110_E	0.516	0.64
297_V	373_K	0.516	0.64
190_L	201_D	0.516	0.64
212_H	313_S	0.515	0.64
311_Y	370_M	0.515	0.64
119_E	122_E	0.515	0.64
519_T	527_V	0.515	0.64
171_T	184_M	0.514	0.63
225_A	271_A	0.513	0.63
334_K	391_A	0.513	0.63
131_L	137_E	0.513	0.63
556_Y	560_V	0.513	0.63
24_G	38_G	0.513	0.63
291_S	508_L	0.513	0.63
394_K	398_K	0.513	0.63
342_D	352_K	0.513	0.63
34_R	60_H	0.513	0.63
57_Q	69_N	0.512	0.63
529_D	532_I	0.512	0.63
37_F	230_Q	0.512	0.63
63_G	89_L	0.512	0.63
128_Y	162_Y	0.512	0.63
96_D	100_D	0.512	0.63
540_L	544_V	0.511	0.63
500_E	531_H	0.510	0.63
6_P	12_Q	0.508	0.63
75_R	82_F	0.508	0.63
523_L	536_L	0.508	0.63
396_V	400_I	0.508	0.63
325_S	388_D	0.508	0.63
122_E	212_H	0.507	0.62
540_L	549_S	0.507	0.62
130_H	173_F	0.507	0.62
266_L	327_L	0.507	0.62
476_A	542_L	0.507	0.62
507_Y	511_F	0.506	0.62
518_L	523_L	0.506	0.62
114_E	306_E	0.506	0.62
378_R	383_L	0.505	0.62
275_S	284_S	0.505	0.62
372_F	415_Q	0.505	0.62
27_V	50_F	0.505	0.62
65_G	319_E	0.505	0.62
121_H	208_M	0.505	0.62
34_R	48_P	0.504	0.62
23_I	74_L	0.504	0.62
27_V	52_V	0.503	0.62
473_L	476_A	0.502	0.62
585_F	592_A	0.502	0.62
19_I	23_I	0.502	0.62
168_D	204_R	0.501	0.62
56_K	69_N	0.501	0.62
457_K	460_Q	0.501	0.62
318_Y	321_T	0.500	0.61

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2au3A	1	0.6667	100	0.358	Contact Map
1dd9A	1	0.5075	100	0.522	Contact Map
4edgA	1	0.529	100	0.537	Contact Map
1nuiA	1	0.3897	100	0.753	Contact Map
1q57A	3	0.6269	100	0.786	Contact Map
1d0qA	2	0.1692	100	0.793	Contact Map
1t6t1	2	0.1692	100	0.842	Contact Map
2r6aC	1	0.2338	99	0.93	Contact Map
2fcjA	2	0.1857	98.9	0.933	Contact Map
2lznA	1	0.2355	98.7	0.937	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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