GREMLIN Database
DNAG - DNA primase
UniProt: P05096 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 603 (575)
Sequences: 3921 (2928)
Seq/√Len: 122.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
66_A76_Q5.3301.00
191_I202_R3.5581.00
213_D217_A3.5161.00
32_Q37_F3.4741.00
219_V247_L3.4341.00
168_D172_K3.3161.00
222_S270_F3.1741.00
344_L348_D3.1161.00
121_H241_L3.0911.00
139_Q143_D2.9821.00
37_F51_S2.9211.00
113_G186_K2.9041.00
344_L352_K2.8861.00
127_F169_F2.8761.00
40_C64_C2.8731.00
45_E63_G2.8611.00
25_D92_K2.8521.00
146_L152_K2.8261.00
40_C43_H2.7881.00
59_F76_Q2.7431.00
43_H64_C2.6471.00
12_Q16_S2.6241.00
17_A93_Y2.5181.00
60_H65_G2.4921.00
124_L189_L2.4731.00
116_K183_Q2.4631.00
166_S169_F2.4611.00
186_K240_P2.4371.00
367_V375_Q2.4361.00
20_V36_Y2.4311.00
145_L207_V2.4241.00
306_E334_K2.4221.00
87_S99_D2.4211.00
154_L278_S2.4061.00
117_M241_L2.4041.00
125_K159_Q2.3961.00
17_A22_V2.3391.00
157_E282_K2.3221.00
143_D147_S2.3141.00
162_Y205_N2.3101.00
263_R283_E2.2741.00
212_H252_Y2.2581.00
264_A300_L2.2381.00
29_L52_V2.2271.00
125_K218_V2.2111.00
385_D388_D2.1951.00
80_Y88_H2.1851.00
287_T311_Y2.1831.00
257_H282_K2.1811.00
315_K319_E2.1461.00
40_C63_G2.1241.00
222_S288_M2.1211.00
45_E50_F2.1161.00
246_K295_D2.1021.00
171_T190_L2.0811.00
27_V38_G2.0621.00
182_A186_K2.0451.00
34_R55_D2.0331.00
129_H159_Q2.0311.00
81_S84_E2.0171.00
124_L170_I1.9971.00
209_F249_Y1.9861.00
371_A415_Q1.9731.00
141_A207_V1.9561.00
308_I338_A1.9411.00
43_H63_G1.9401.00
212_H253_K1.9321.00
225_A229_Q1.9311.00
22_V70_V1.9301.00
355_G359_K1.9211.00
258_I264_A1.8841.00
263_R306_E1.8721.00
152_K156_N1.8561.00
349_Y353_F1.8511.00
123_L179_F1.8461.00
150_F271_A1.8431.00
175_V181_E1.8371.00
151_T154_L1.8161.00
231_P234_M1.8131.00
185_E192_R1.8091.00
378_R419_E1.7871.00
306_E336_R1.7831.00
152_K155_I1.7831.00
165_D205_N1.7771.00
82_F86_V1.7741.00
220_A236_S1.7731.00
587_R590_S1.7671.00
18_D54_P1.7601.00
9_I13_V1.7581.00
35_N53_S1.7581.00
53_S56_K1.7481.00
140_E205_N1.7341.00
319_E323_K1.7301.00
72_S76_Q1.7251.00
287_T296_H1.7241.00
78_E88_H1.7191.00
123_L177_R1.7141.00
180_S183_Q1.7111.00
60_H67_G1.7101.00
26_Y78_E1.7001.00
125_K129_H1.6971.00
359_K364_D1.6961.00
184_M190_L1.6821.00
35_N51_S1.6581.00
380_G395_D1.6581.00
14_Q69_N1.6471.00
225_A230_Q1.6461.00
487_K550_E1.6411.00
242_F288_M1.6391.00
13_V86_V1.6381.00
356_E360_N1.6371.00
131_L164_L1.6191.00
38_G52_V1.6171.00
26_Y77_M1.6021.00
59_F66_A1.6001.00
159_Q212_H1.5901.00
9_I98_P1.5871.00
157_E253_K1.5871.00
142_L152_K1.5801.00
415_Q418_S1.5771.00
584_D587_R1.5721.00
313_S344_L1.5641.00
129_H156_N1.5581.00
238_E243_H1.5561.00
117_M187_A1.5541.00
69_N72_S1.5431.00
142_L146_L1.5371.00
17_A70_V1.5311.00
155_I160_I1.5271.00
374_M396_V1.5271.00
187_A190_L1.5221.00
121_H220_A1.5141.00
47_T50_F1.5011.00
568_M571_E1.4991.00
118_A217_A1.4911.00
151_T278_S1.4851.00
14_Q70_V1.4721.00
413_V427_L1.4671.00
397_L431_L1.4641.00
167_W204_R1.4631.00
267_F284_S1.4621.00
10_V86_V1.4501.00
381_K395_D1.4481.00
61_C64_C1.4441.00
122_E159_Q1.4401.00
167_W200_F1.4381.00
336_R366_S1.4381.00
47_T63_G1.4291.00
297_V327_L1.4181.00
142_L155_I1.4171.00
18_D21_E1.4131.00
132_L145_L1.4121.00
40_C61_C1.4081.00
14_Q71_F1.4061.00
236_S239_T1.4051.00
74_L88_H1.4051.00
121_H187_A1.4041.00
7_D11_D1.3991.00
50_F63_G1.3881.00
11_D15_K1.3871.00
360_N365_A1.3731.00
202_R237_P1.3731.00
138_G142_L1.3721.00
118_A241_L1.3721.00
338_A362_I1.3681.00
53_S58_I1.3631.00
171_T181_E1.3451.00
267_F276_A1.3211.00
200_F204_R1.3191.00
133_I142_L1.3091.00
354_G357_K1.3091.00
245_S295_D1.3061.00
360_N364_D1.3011.00
127_F131_L1.2891.00
153_E156_N1.2851.00
163_A208_M1.2851.00
310_C358_F1.2841.00
173_F177_R1.2801.00
187_A239_T1.2711.00
250_N277_V1.2671.00
297_V328_L1.2641.00
133_I152_K1.2631.00
146_L155_I1.2591.00
116_K119_E1.2581.00
13_V95_I1.2571.00
9_I95_I1.2530.99
43_H61_C1.2460.99
414_K424_Q1.2340.99
29_L38_G1.2340.99
136_K139_Q1.2290.99
243_H246_K1.2270.99
350_I358_F1.2270.99
60_H66_A1.2220.99
340_I362_I1.2200.99
185_E199_Y1.2190.99
122_E126_K1.2170.99
145_L155_I1.2140.99
325_S369_V1.2110.99
17_A89_L1.2070.99
310_C340_I1.2070.99
46_S63_G1.2040.99
551_A555_D1.2030.99
281_V359_K1.2030.99
127_F164_L1.1990.99
115_Q119_E1.1990.99
171_T175_V1.1970.99
179_F184_M1.1970.99
525_A528_T1.1930.99
586_L589_A1.1920.99
270_F288_M1.1920.99
35_N58_I1.1910.99
17_A92_K1.1890.99
87_S91_D1.1830.99
245_S296_H1.1790.99
570_K573_E1.1780.99
20_V54_P1.1770.99
19_I22_V1.1670.99
190_L199_Y1.1670.99
121_H236_S1.1630.99
6_P98_P1.1600.99
391_A395_D1.1590.99
16_S95_I1.1560.99
129_H133_I1.1550.99
174_L184_M1.1540.99
172_K176_K1.1510.99
276_A350_I1.1500.99
193_R200_F1.1480.99
9_I97_F1.1450.99
185_E190_L1.1430.99
502_R506_A1.1420.99
74_L80_Y1.1420.99
322_L373_K1.1390.99
135_T138_G1.1370.99
83_A87_S1.1300.99
160_I274_I1.1270.99
566_W570_K1.1250.99
247_L288_M1.1240.99
262_E305_E1.1230.99
120_A183_Q1.1190.99
89_L92_K1.1190.99
261_Q359_K1.1190.99
139_Q142_L1.1080.99
279_S355_G1.1060.99
344_L353_F1.1050.99
12_Q15_K1.1050.99
80_Y85_S1.1040.99
158_F277_V1.1020.99
545_N548_L1.1000.99
250_N273_V1.0980.99
60_H63_G1.0930.99
281_V350_I1.0930.99
250_N253_K1.0920.99
122_E217_A1.0890.99
225_A231_P1.0870.99
211_I222_S1.0860.99
26_Y73_F1.0850.99
559_K562_N1.0820.99
150_F155_I1.0800.98
18_D57_Q1.0780.98
32_Q51_S1.0760.98
409_Q413_V1.0750.98
138_G141_A1.0670.98
581_R584_D1.0660.98
71_F86_V1.0610.98
39_L45_E1.0610.98
106_G109_P1.0590.98
212_H218_V1.0540.98
121_H128_Y1.0470.98
145_L160_I1.0460.98
474_L553_L1.0460.98
150_F209_F1.0440.98
555_D559_K1.0400.98
23_I27_V1.0400.98
301_R333_C1.0400.98
192_R199_Y1.0400.98
59_F67_G1.0390.98
415_Q419_E1.0380.98
123_L173_F1.0360.98
202_R234_M1.0360.98
307_I328_L1.0330.98
423_S426_S1.0280.98
285_I300_L1.0280.98
143_D146_L1.0270.98
193_R197_S1.0260.98
305_E333_C1.0250.98
574_A578_E1.0240.98
356_E359_K1.0170.98
328_L335_V1.0170.98
123_L126_K1.0150.98
590_S593_Q1.0140.98
17_A21_E1.0090.98
347_D351_K1.0090.98
276_A358_F1.0070.98
208_M223_G1.0060.98
29_L33_G1.0000.98
291_S323_K0.9970.97
575_E587_R0.9960.97
381_K388_D0.9950.97
203_F208_M0.9930.97
311_Y324_A0.9910.97
382_N385_D0.9900.97
57_Q70_V0.9890.97
88_H92_K0.9880.97
579_A584_D0.9870.97
120_A179_F0.9870.97
40_C66_A0.9870.97
491_R561_L0.9850.97
58_I67_G0.9840.97
19_I59_F0.9840.97
191_I200_F0.9830.97
523_L527_V0.9810.97
569_I573_E0.9790.97
571_E575_E0.9780.97
283_E359_K0.9770.97
13_V71_F0.9760.97
182_A185_E0.9760.97
225_A228_S0.9750.97
292_L297_V0.9740.97
46_S50_F0.9730.97
589_A593_Q0.9710.97
382_N388_D0.9700.97
140_E143_D0.9680.97
138_G207_V0.9620.97
17_A74_L0.9610.97
36_Y54_P0.9530.97
35_N56_K0.9520.97
71_F89_L0.9490.97
162_Y226_L0.9480.97
378_R392_Y0.9480.97
586_L590_S0.9480.97
245_S293_T0.9470.97
287_T309_L0.9450.96
573_E577_A0.9450.96
234_M242_F0.9450.96
133_I156_N0.9400.96
287_T324_A0.9340.96
263_R364_D0.9340.96
24_G28_Q0.9330.96
11_D14_Q0.9320.96
265_V281_V0.9310.96
292_L324_A0.9310.96
570_K574_A0.9280.96
5_I83_A0.9260.96
174_L179_F0.9250.96
120_A187_A0.9250.96
585_F588_A0.9250.96
149_G351_K0.9190.96
188_G237_P0.9180.96
44_G63_G0.9120.96
353_F357_K0.9120.96
568_M572_K0.9110.96
181_E199_Y0.9100.96
39_L47_T0.9090.96
257_H261_Q0.9070.96
273_V284_S0.9030.95
553_L557_V0.9020.95
120_A124_L0.9000.95
124_L128_Y0.8990.95
357_K360_N0.8980.95
84_E87_S0.8970.95
51_S58_I0.8970.95
227_G231_P0.8930.95
39_L46_S0.8920.95
74_L77_M0.8910.95
424_Q428_T0.8890.95
5_I10_V0.8840.95
133_I155_I0.8830.95
38_G50_F0.8770.95
26_Y88_H0.8770.95
349_Y358_F0.8760.95
471_E501_H0.8740.95
386_E411_V0.8730.95
183_Q186_K0.8710.94
39_L63_G0.8700.94
265_V363_I0.8700.94
191_I234_M0.8680.94
251_F303_N0.8600.94
313_S343_G0.8590.94
375_Q419_E0.8560.94
275_S279_S0.8550.94
249_Y270_F0.8540.94
128_Y170_I0.8520.94
164_L169_F0.8520.94
583_K588_A0.8520.94
498_I501_H0.8510.94
266_L309_L0.8500.94
12_Q95_I0.8450.94
193_R196_G0.8450.94
5_I9_I0.8450.94
222_S234_M0.8450.94
205_N227_G0.8440.94
413_V428_T0.8400.93
265_V276_A0.8400.93
128_Y169_F0.8390.93
223_G270_F0.8360.93
13_V17_A0.8360.93
167_W193_R0.8360.93
88_H91_D0.8340.93
39_L50_F0.8340.93
530_D533_S0.8340.93
520_P523_L0.8310.93
181_E192_R0.8300.93
296_H311_Y0.8270.93
475_L505_A0.8270.93
119_E123_L0.8270.93
263_R308_I0.8260.93
301_R305_E0.8230.93
425_E428_T0.8230.93
155_I207_V0.8220.93
170_I174_L0.8210.93
192_R196_G0.8210.93
79_G259_R0.8210.93
72_S75_R0.8190.92
125_K208_M0.8170.92
76_Q79_G0.8110.92
127_F173_F0.8110.92
387_G391_A0.8100.92
318_Y339_M0.8090.92
181_E185_E0.8090.92
277_V282_K0.8080.92
505_A509_Y0.8080.92
489_I513_E0.8060.92
220_A247_L0.8060.92
574_A577_A0.8060.92
579_A583_K0.8060.92
153_E157_E0.8060.92
377_F396_V0.8050.92
567_S571_E0.8030.92
396_V416_L0.8030.92
141_A145_L0.8010.92
184_M187_A0.7990.92
519_T522_H0.7980.91
550_E554_S0.7980.91
131_L135_T0.7980.91
273_V313_S0.7950.91
430_Q433_V0.7950.91
8_E12_Q0.7930.91
168_D171_T0.7930.91
300_L333_C0.7920.91
216_G252_Y0.7910.91
157_E277_V0.7910.91
263_R304_V0.7900.91
313_S341_P0.7900.91
414_K418_S0.7880.91
528_T533_S0.7880.91
422_L427_L0.7880.91
90_A93_Y0.7870.91
348_D351_K0.7860.91
9_I12_Q0.7860.91
342_D353_F0.7820.91
587_R591_L0.7820.91
242_F296_H0.7810.91
167_W195_D0.7790.90
417_A427_L0.7790.90
28_Q39_L0.7780.90
37_F58_I0.7750.90
367_V371_A0.7750.90
243_H295_D0.7730.90
417_A422_L0.7720.90
519_T523_L0.7690.90
43_H66_A0.7690.90
37_F48_P0.7670.90
567_S570_K0.7620.89
91_D96_D0.7620.89
397_L413_V0.7610.89
403_L412_Y0.7580.89
262_E306_E0.7580.89
340_I344_L0.7550.89
209_F271_A0.7550.89
477_H553_L0.7500.89
410_E423_S0.7490.89
263_R359_K0.7480.89
291_S321_T0.7470.89
534_Q538_D0.7460.88
506_A510_A0.7460.88
5_I97_F0.7440.88
583_K586_L0.7430.88
5_I86_V0.7420.88
578_E582_Q0.7420.88
432_S435_S0.7410.88
30_K33_G0.7410.88
321_T339_M0.7400.88
287_T291_S0.7400.88
220_A243_H0.7380.88
90_A97_F0.7380.88
377_F395_D0.7370.88
322_L376_Y0.7360.88
292_L311_Y0.7320.88
413_V417_A0.7280.87
158_F249_Y0.7280.87
341_P344_L0.7250.87
277_V284_S0.7240.87
265_V310_C0.7240.87
38_G77_M0.7240.87
338_A363_I0.7210.87
128_Y163_A0.7210.87
211_I247_L0.7200.87
588_A592_A0.7180.87
294_D327_L0.7150.86
326_E402_T0.7150.86
473_L552_E0.7140.86
115_Q217_A0.7110.86
23_I77_M0.7110.86
163_A205_N0.7110.86
294_D330_K0.7090.86
299_I303_N0.7070.86
571_E574_A0.7070.86
376_Y379_K0.7070.86
188_G202_R0.7040.85
222_S250_N0.7040.85
258_I304_V0.7030.85
363_I366_S0.7030.85
502_R505_A0.7020.85
510_A514_E0.7010.85
292_L309_L0.7000.85
299_I302_R0.7000.85
211_I220_A0.6990.85
430_Q434_F0.6990.85
368_T371_A0.6980.85
373_K399_E0.6970.85
397_L434_F0.6970.85
297_V333_C0.6960.85
250_N288_M0.6960.85
572_K576_R0.6940.85
471_E496_F0.6940.85
261_Q282_K0.6940.85
108_R112_S0.6930.85
267_F273_V0.6910.84
309_L337_V0.6900.84
10_V13_V0.6900.84
109_P113_G0.6880.84
124_L201_D0.6860.84
81_S88_H0.6850.84
471_E498_I0.6850.84
207_V226_L0.6850.84
572_K575_E0.6820.84
580_E583_K0.6820.84
576_R591_L0.6810.84
406_S409_Q0.6800.83
18_D36_Y0.6780.83
281_V363_I0.6780.83
529_D533_S0.6780.83
546_Q549_S0.6780.83
588_A591_L0.6770.83
413_V431_L0.6770.83
301_R331_K0.6760.83
326_E373_K0.6760.83
59_F72_S0.6760.83
170_I189_L0.6750.83
23_I52_V0.6750.83
5_I17_A0.6730.83
392_Y420_F0.6730.83
576_R580_E0.6730.83
279_S350_I0.6710.83
37_F47_T0.6690.82
386_E390_L0.6680.82
203_F234_M0.6680.82
300_L307_I0.6640.82
313_S362_I0.6630.82
411_V414_K0.6620.82
581_R588_A0.6610.82
411_V415_Q0.6610.82
413_V424_Q0.6600.82
383_L388_D0.6600.82
20_V57_Q0.6580.81
568_M587_R0.6580.81
69_N75_R0.6580.81
578_E581_R0.6570.81
389_R411_V0.6560.81
125_K221_F0.6560.81
276_A284_S0.6550.81
434_F437_Q0.6550.81
296_H299_I0.6530.81
465_P468_E0.6530.81
123_L174_L0.6510.81
410_E426_S0.6510.81
318_Y376_Y0.6510.81
308_I363_I0.6480.80
261_Q283_E0.6480.80
265_V308_I0.6470.80
23_I70_V0.6460.80
201_D204_R0.6460.80
45_E60_H0.6460.80
535_L538_D0.6440.80
391_A394_K0.6430.80
275_S278_S0.6430.80
262_E304_V0.6420.80
410_E428_T0.6420.80
126_K159_Q0.6420.80
117_M121_H0.6420.80
336_R385_D0.6410.80
323_K326_E0.6390.79
181_E190_L0.6390.79
142_L207_V0.6380.79
579_A588_A0.6370.79
120_A123_L0.6360.79
470_A474_L0.6350.79
25_D38_G0.6340.79
111_S115_Q0.6310.79
353_F360_N0.6300.79
167_W201_D0.6290.78
426_S430_Q0.6280.78
309_L328_L0.6270.78
28_Q38_G0.6270.78
242_F247_L0.6270.78
24_G319_E0.6260.78
329_Q402_T0.6250.78
403_L408_E0.6240.78
266_L311_Y0.6230.78
220_A250_N0.6230.78
479_L508_L0.6230.78
112_S116_K0.6220.78
339_M375_Q0.6220.78
395_D398_K0.6210.78
313_S346_P0.6200.77
22_V73_F0.6200.77
181_E184_M0.6190.77
487_K554_S0.6180.77
51_S60_H0.6150.77
310_C338_A0.6150.77
31_K36_Y0.6150.77
441_A446_E0.6150.77
249_Y273_V0.6140.77
274_I350_I0.6140.77
552_E555_D0.6140.77
445_G448_K0.6140.77
21_E39_L0.6130.77
113_G240_P0.6130.77
257_H260_K0.6120.77
246_K321_T0.6120.77
291_S309_L0.6110.76
55_D259_R0.6100.76
22_V89_L0.6100.76
227_G230_Q0.6100.76
167_W191_I0.6100.76
409_Q435_S0.6100.76
131_L169_F0.6100.76
581_R585_F0.6090.76
264_A304_V0.6090.76
580_E588_A0.6090.76
171_T199_Y0.6080.76
471_E497_N0.6080.76
441_A444_S0.6080.76
392_Y395_D0.6070.76
475_L504_L0.6060.76
120_A189_L0.6060.76
576_R579_A0.6060.76
23_I38_G0.6050.76
126_K129_H0.6050.76
536_L540_L0.6040.76
440_P443_N0.6040.76
51_S69_N0.6040.76
75_R83_A0.6040.76
63_G66_A0.6040.76
45_E49_S0.5990.75
7_D14_Q0.5950.74
163_A242_F0.5940.74
20_V24_G0.5930.74
179_F187_A0.5930.74
160_I270_F0.5930.74
575_E579_A0.5930.74
147_S207_V0.5920.74
28_Q57_Q0.5920.74
575_E578_E0.5920.74
408_E411_V0.5920.74
211_I288_M0.5910.74
548_L551_A0.5910.74
576_R581_R0.5910.74
13_V70_V0.5900.74
6_P10_V0.5890.74
321_T325_S0.5890.74
468_E501_H0.5890.74
247_L251_F0.5880.74
128_Y201_D0.5860.73
209_F274_I0.5850.73
504_L532_I0.5850.73
468_E498_I0.5850.73
406_S410_E0.5850.73
51_S67_G0.5850.73
74_L78_E0.5840.73
6_P9_I0.5830.73
523_L526_R0.5830.73
329_Q337_V0.5830.73
187_A236_S0.5820.73
175_V184_M0.5820.73
577_A581_R0.5810.73
81_S476_A0.5800.73
377_F399_E0.5800.73
511_F523_L0.5800.73
166_S205_N0.5790.72
211_I231_P0.5780.72
5_I100_D0.5770.72
401_S434_F0.5760.72
156_N159_Q0.5760.72
75_R80_Y0.5750.72
393_I427_L0.5730.72
175_V178_G0.5720.72
371_A375_Q0.5720.72
150_F154_L0.5710.71
256_L260_K0.5680.71
211_I270_F0.5680.71
474_L556_Y0.5680.71
183_Q187_A0.5680.71
116_K180_S0.5680.71
579_A582_Q0.5670.71
370_M387_G0.5670.71
432_S436_K0.5660.71
107_A110_E0.5660.71
368_T403_L0.5660.71
276_A310_C0.5660.71
545_N549_S0.5650.71
275_S351_K0.5650.71
350_I354_G0.5640.71
534_Q537_S0.5620.70
267_F281_V0.5620.70
524_M527_V0.5620.70
121_H190_L0.5610.70
275_S350_I0.5600.70
51_S59_F0.5600.70
343_G348_D0.5600.70
8_E11_D0.5590.70
401_S409_Q0.5590.70
381_K392_Y0.5590.70
71_F77_M0.5580.70
187_A199_Y0.5580.70
109_P112_S0.5580.70
478_M508_L0.5570.70
7_D10_V0.5550.69
202_R236_S0.5550.69
557_V561_L0.5540.69
572_K591_L0.5540.69
23_I59_F0.5540.69
167_W194_E0.5540.69
271_A347_D0.5530.69
377_F392_Y0.5530.69
214_H255_R0.5530.69
126_K177_R0.5520.69
562_N566_W0.5520.69
386_E408_E0.5500.69
263_R366_S0.5500.69
209_F273_V0.5490.68
522_H525_A0.5480.68
250_N270_F0.5460.68
190_L202_R0.5450.68
478_M488_V0.5450.68
19_I35_N0.5440.68
520_P524_M0.5440.68
203_F236_S0.5440.68
154_L157_E0.5430.68
585_F589_A0.5420.68
249_Y271_A0.5400.67
273_V277_V0.5400.67
261_Q304_V0.5400.67
548_L556_Y0.5400.67
294_D298_K0.5390.67
6_P241_L0.5380.67
132_L160_I0.5370.67
470_A556_Y0.5370.67
120_A174_L0.5370.67
258_I262_E0.5360.67
125_K212_H0.5360.67
527_V532_I0.5350.67
163_A204_R0.5350.67
208_M221_F0.5350.67
214_H303_N0.5350.67
39_L44_G0.5330.66
485_I509_Y0.5320.66
290_T313_S0.5320.66
13_V90_A0.5320.66
162_Y207_V0.5310.66
45_E66_A0.5300.66
520_P540_L0.5300.66
226_L275_S0.5300.66
504_L508_L0.5280.66
78_E255_R0.5280.66
573_E576_R0.5280.66
408_E412_Y0.5270.65
250_N267_F0.5270.65
162_Y227_G0.5270.65
60_H74_L0.5260.65
478_M485_I0.5260.65
20_V53_S0.5260.65
47_T266_L0.5260.65
265_V283_E0.5260.65
51_S56_K0.5260.65
19_I40_C0.5250.65
322_L377_F0.5250.65
79_G274_I0.5240.65
253_K277_V0.5240.65
442_D447_T0.5230.65
160_I207_V0.5230.65
551_A554_S0.5230.65
160_I209_F0.5220.65
577_A580_E0.5220.65
394_K430_Q0.5220.65
410_E424_Q0.5210.65
313_S339_M0.5210.65
165_D204_R0.5210.65
114_E240_P0.5200.64
533_S544_V0.5200.64
429_E432_S0.5200.64
193_R199_Y0.5200.64
189_L208_M0.5190.64
393_I407_L0.5180.64
584_D593_Q0.5180.64
256_L259_R0.5170.64
572_K584_D0.5170.64
400_I409_Q0.5170.64
106_G110_E0.5160.64
297_V373_K0.5160.64
190_L201_D0.5160.64
212_H313_S0.5150.64
311_Y370_M0.5150.64
119_E122_E0.5150.64
519_T527_V0.5150.64
171_T184_M0.5140.63
225_A271_A0.5130.63
334_K391_A0.5130.63
131_L137_E0.5130.63
556_Y560_V0.5130.63
24_G38_G0.5130.63
291_S508_L0.5130.63
394_K398_K0.5130.63
342_D352_K0.5130.63
34_R60_H0.5130.63
57_Q69_N0.5120.63
529_D532_I0.5120.63
37_F230_Q0.5120.63
63_G89_L0.5120.63
128_Y162_Y0.5120.63
96_D100_D0.5120.63
540_L544_V0.5110.63
500_E531_H0.5100.63
6_P12_Q0.5080.63
75_R82_F0.5080.63
523_L536_L0.5080.63
396_V400_I0.5080.63
325_S388_D0.5080.63
122_E212_H0.5070.62
540_L549_S0.5070.62
130_H173_F0.5070.62
266_L327_L0.5070.62
476_A542_L0.5070.62
507_Y511_F0.5060.62
518_L523_L0.5060.62
114_E306_E0.5060.62
378_R383_L0.5050.62
275_S284_S0.5050.62
372_F415_Q0.5050.62
27_V50_F0.5050.62
65_G319_E0.5050.62
121_H208_M0.5050.62
34_R48_P0.5040.62
23_I74_L0.5040.62
27_V52_V0.5030.62
473_L476_A0.5020.62
585_F592_A0.5020.62
19_I23_I0.5020.62
168_D204_R0.5010.62
56_K69_N0.5010.62
457_K460_Q0.5010.62
318_Y321_T0.5000.61
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2au3A 1 0.6667 100 0.358 Contact Map
1dd9A 1 0.5075 100 0.522 Contact Map
4edgA 1 0.529 100 0.537 Contact Map
1nuiA 1 0.3897 100 0.753 Contact Map
1q57A 3 0.6269 100 0.786 Contact Map
1d0qA 2 0.1692 100 0.793 Contact Map
1t6t1 2 0.1692 100 0.842 Contact Map
2r6aC 1 0.2338 99 0.93 Contact Map
2fcjA 2 0.1857 98.9 0.933 Contact Map
2lznA 1 0.2355 98.7 0.937 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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