GREMLIN Database
RS11 - 30S ribosomal protein S11
UniProt: P04969 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 131 (123)
Sequences: 1835 (794)
Seq/√Len: 71.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
35_T43_A3.8411.00
22_I87_T3.5391.00
21_G81_L3.5391.00
38_D42_N3.1981.00
85_E111_A2.9871.00
84_L107_L2.9251.00
85_E110_T2.7721.00
47_S71_T2.6611.00
23_A36_I2.6611.00
72_A76_S2.4481.00
71_T75_G2.2941.00
16_K79_H2.2621.00
23_A84_L2.1551.00
36_I72_A2.0881.00
47_S51_A2.0761.00
73_A105_A2.0521.00
83_T108_E2.0061.00
20_S83_T2.0041.00
44_I81_L1.7981.00
34_V72_A1.6861.00
57_S60_S1.6380.99
86_V102_L1.6310.99
87_T115_V1.5640.99
24_H37_T1.5420.99
74_K78_E1.5230.99
77_I82_K1.4780.99
102_L107_L1.4580.99
25_I98_A1.4400.99
69_A73_A1.4270.99
32_T60_S1.4190.98
23_A102_L1.3790.98
29_F91_P1.3720.98
36_I76_S1.3610.98
56_G59_K1.3610.98
10_R14_V1.3600.98
44_I79_H1.3510.98
74_K77_I1.3240.98
19_E39_T1.3030.97
26_R33_I1.2970.97
18_I79_H1.2890.97
95_R114_D1.2480.97
37_T41_G1.2470.97
36_I102_L1.2350.96
51_A71_T1.2180.96
24_H115_V1.2070.96
88_V99_I1.1980.96
49_A52_L1.1830.95
47_S52_L1.1690.95
17_N79_H1.1660.95
52_L67_M1.1620.95
87_T113_R1.1560.95
83_T110_T1.1510.95
9_T12_R1.1220.94
88_V98_A1.0650.92
45_S72_A1.0370.91
87_T111_A1.0360.91
61_T64_A1.0350.91
94_G116_T1.0230.90
100_R131_V1.0090.90
30_N59_K1.0080.90
51_A75_G0.9980.89
10_R13_R0.9760.88
9_T14_V0.9700.88
33_I41_G0.9640.87
27_S94_G0.9630.87
22_I39_T0.9630.87
20_S39_T0.9570.87
36_I81_L0.9460.86
63_F67_M0.9160.85
58_R120_H0.9030.84
69_A101_A0.8940.83
73_A107_L0.8770.82
52_L63_F0.8530.80
89_K115_V0.8420.79
11_K14_V0.8360.79
19_E40_H0.8300.78
119_P123_C0.8200.78
14_V17_N0.7970.76
53_G71_T0.7850.74
38_D41_G0.7680.73
52_L71_T0.7660.73
18_I44_I0.7630.72
31_N122_G0.7590.72
119_P122_G0.7530.71
128_R131_V0.7520.71
12_R17_N0.7510.71
106_G119_P0.7450.70
27_S67_M0.7400.70
120_H123_C0.7360.70
84_L109_V0.7270.69
29_F60_S0.7250.68
94_G114_D0.7220.68
46_W51_A0.7200.68
48_S53_G0.7140.67
32_T58_R0.7130.67
26_R89_K0.7110.67
14_V79_H0.7000.66
49_A68_A0.6930.65
32_T94_G0.6930.65
15_K97_A0.6910.65
48_S90_G0.6860.64
99_I108_E0.6840.64
114_D124_R0.6830.64
36_I107_L0.6830.64
59_K111_A0.6810.64
62_P93_S0.6790.63
119_P125_P0.6790.63
18_I38_D0.6780.63
30_N100_R0.6770.63
30_N129_R0.6750.63
70_E74_K0.6670.62
56_G90_G0.6660.62
32_T65_A0.6610.61
45_S104_A0.6590.61
83_T97_A0.6560.61
54_F66_Q0.6510.60
54_F129_R0.6510.60
14_V75_G0.6480.60
29_F70_E0.6380.59
27_S62_P0.6300.58
26_R93_S0.6290.57
103_Q109_V0.6290.57
66_Q95_R0.6260.57
124_R129_R0.6220.57
60_S64_A0.6190.56
91_P97_A0.6150.56
96_E100_R0.6100.55
48_S51_A0.6090.55
48_S124_R0.6080.55
65_A72_A0.6080.55
25_I115_V0.6070.55
59_K62_P0.6010.54
39_T108_E0.5980.54
55_R75_G0.5980.54
10_R40_H0.5970.54
26_R129_R0.5960.53
23_A72_A0.5890.53
44_I59_K0.5880.52
81_L98_A0.5840.52
13_R26_R0.5770.51
57_S67_M0.5760.51
24_H87_T0.5750.51
82_K126_P0.5730.51
63_F120_H0.5730.51
17_N75_G0.5700.50
27_S99_I0.5700.50
52_L68_A0.5690.50
26_R35_T0.5690.50
76_S79_H0.5670.50
14_V19_E0.5660.50
54_F64_A0.5630.49
90_G122_G0.5630.49
97_A101_A0.5620.49
10_R19_E0.5620.49
75_G79_H0.5560.49
45_S78_E0.5560.49
26_R110_T0.5550.48
62_P91_P0.5550.48
66_Q91_P0.5540.48
54_F116_T0.5530.48
33_I49_A0.5510.48
63_F70_E0.5510.48
73_A77_I0.5430.47
122_G127_K0.5420.47
13_R72_A0.5410.47
25_I99_I0.5400.47
54_F59_K0.5390.46
26_R113_R0.5360.46
43_A116_T0.5350.46
34_V98_A0.5340.46
103_Q111_A0.5320.46
30_N88_V0.5290.45
20_S110_T0.5280.45
19_E43_A0.5280.45
66_Q123_C0.5240.45
90_G127_K0.5220.44
12_R87_T0.5200.44
30_N60_S0.5170.44
35_T44_I0.5140.43
33_I123_C0.5090.43
28_T93_S0.5060.42
47_S72_A0.5060.42
9_T75_G0.5040.42
97_A121_N0.5000.42
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4rb5K 1 0.8702 100 0.042 Contact Map
3bbnK 1 0.8931 100 0.052 Contact Map
4tp8K 1 0.0153 100 0.07 Contact Map
3zeyH 1 0.8855 100 0.081 Contact Map
5aj3K 1 0.9466 100 0.082 Contact Map
3j7aP 1 0.8779 100 0.085 Contact Map
4ujpP 1 0.8779 100 0.098 Contact Map
4cvnE 1 0.8702 100 0.098 Contact Map
4rb6S 1 0.7939 97.2 0.836 Contact Map
4tp9O 1 0.0153 97.1 0.837 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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