GUB - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

GUB - Beta-glucanase

UniProt:	P04957	Sequences: MPYLKRVLLLLVTGLFMSLFAVTATASAQTGGSFFDPFNGYNSGFWQKADGYSNGNMFNCTWRANNVSMTSLGEMRLALTSPAYNKFDCGENRSVQTYGYGLYEVRMKPAKNTGIVSSFFTYTGPTDGTPWDEIDIEFLGKDTTKVQFNYYTNGAGNHEKIVDLGFDAANAYHTYAFDWQPNSIKWYVDGQLKHTATNQIPTTPGKIMMNLWNGTGVDEWLGSYNGVNPLYAHYDWVRYTKK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	242 (215)
Sequences:	3916 (2991)
Seq/√Len:	204.0

BACSU - GUB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
173_H	189_D	4.939	1.00
185_K	192_L	3.877	1.00
105_V	119_F	3.645	1.00
192_L	195_T	3.305	1.00
102_L	176_A	3.031	1.00
187_Y	192_L	3.021	1.00
68_S	78_A	3.019	1.00
42_N	45_F	3.004	1.00
106_R	235_D	2.908	1.00
67_V	90_G	2.794	1.00
76_R	233_H	2.677	1.00
107_M	119_F	2.668	1.00
78_A	231_Y	2.620	1.00
74_E	233_H	2.531	1.00
148_F	193_K	2.430	1.00
76_R	231_Y	2.428	1.00
104_E	176_A	2.420	1.00
185_K	195_T	2.337	1.00
102_L	178_D	2.324	1.00
37_P	238_R	2.259	1.00
177_F	184_I	2.247	1.00
108_K	233_H	2.235	1.00
172_Y	233_H	2.171	1.00
48_K	67_V	2.156	1.00
107_M	232_A	2.035	1.00
121_T	205_G	2.017	1.00
148_F	186_W	2.009	1.00
47_Q	93_R	1.988	1.00
183_S	195_T	1.986	1.00
176_A	187_Y	1.934	1.00
103_Y	207_I	1.927	1.00
70_T	76_R	1.926	1.00
106_R	174_T	1.914	1.00
67_V	92_N	1.909	1.00
66_N	88_D	1.865	1.00
99_G	204_P	1.785	1.00
79_L	211_L	1.748	1.00
209_M	237_V	1.694	1.00
119_F	209_M	1.683	1.00
98_Y	239_Y	1.609	1.00
224_Y	228_N	1.587	1.00
32_G	35_F	1.581	1.00
178_D	185_K	1.579	1.00
47_Q	97_T	1.571	1.00
40_G	69_M	1.499	1.00
133_E	137_E	1.495	1.00
106_R	236_W	1.493	1.00
177_F	186_W	1.482	1.00
35_F	238_R	1.471	1.00
74_E	172_Y	1.452	1.00
104_E	174_T	1.444	1.00
70_T	74_E	1.434	1.00
211_L	232_A	1.409	1.00
80_T	88_D	1.392	1.00
115_I	230_L	1.390	1.00
160_K	163_D	1.361	1.00
49_A	93_R	1.359	1.00
121_T	136_I	1.357	1.00
33_S	241_K	1.342	1.00
104_E	236_W	1.311	1.00
82_P	88_D	1.290	1.00
39_N	235_D	1.284	1.00
41_Y	92_N	1.272	1.00
56_N	60_C	1.264	1.00
105_V	209_M	1.259	1.00
32_G	240_T	1.242	1.00
68_S	76_R	1.239	1.00
45_F	98_Y	1.212	1.00
103_Y	136_I	1.203	1.00
174_T	190_G	1.202	1.00
183_S	197_T	1.184	1.00
123_T	131_W	1.179	1.00
109_P	138_F	1.170	1.00
71_S	74_E	1.165	1.00
100_Y	181_P	1.157	1.00
41_Y	48_K	1.139	1.00
115_I	213_N	1.137	1.00
108_K	171_A	1.131	1.00
115_I	211_L	1.122	1.00
36_D	45_F	1.108	1.00
123_T	205_G	1.108	1.00
110_A	117_S	1.095	1.00
122_Y	208_M	1.094	1.00
139_L	147_Q	1.082	1.00
36_D	237_V	1.066	1.00
129_T	132_D	1.057	1.00
103_Y	121_T	1.053	1.00
142_D	145_K	1.052	1.00
118_S	137_E	1.051	1.00
146_V	188_V	1.048	1.00
77_L	92_N	1.045	1.00
132_D	205_G	1.042	1.00
79_L	213_N	1.040	1.00
168_A	175_Y	1.034	1.00
58_F	89_C	1.029	1.00
81_S	87_F	1.019	1.00
207_I	237_V	1.010	1.00
116_V	210_N	1.009	1.00
30_T	102_L	1.009	1.00
128_G	132_D	1.007	1.00
31_G	241_K	1.007	1.00
66_N	80_T	1.003	1.00
120_F	137_E	1.003	1.00
87_F	229_P	0.999	1.00
118_S	133_E	0.995	1.00
116_V	120_F	0.994	1.00
161_I	164_L	0.993	1.00
153_N	157_N	0.981	1.00
187_Y	190_G	0.978	1.00
57_M	224_Y	0.971	1.00
108_K	172_Y	0.967	1.00
225_N	228_N	0.967	1.00
126_T	131_W	0.959	0.99
178_D	187_Y	0.939	0.99
47_Q	96_Q	0.936	0.99
74_E	235_D	0.930	0.99
175_Y	188_V	0.928	0.99
121_T	177_F	0.918	0.99
180_Q	185_K	0.918	0.99
116_V	212_W	0.914	0.99
168_A	188_V	0.914	0.99
167_D	170_N	0.913	0.99
106_R	172_Y	0.910	0.99
124_G	204_P	0.897	0.99
121_T	207_I	0.896	0.99
49_A	52_Y	0.883	0.99
174_T	236_W	0.883	0.99
159_E	162_V	0.876	0.99
99_G	203_T	0.861	0.99
162_V	165_G	0.855	0.99
48_K	90_G	0.851	0.99
94_S	207_I	0.846	0.99
130_P	153_N	0.845	0.99
134_I	150_Y	0.843	0.99
209_M	234_Y	0.841	0.99
119_F	207_I	0.834	0.99
140_G	143_T	0.834	0.99
155_A	158_H	0.831	0.98
54_N	57_M	0.829	0.98
93_R	206_K	0.825	0.98
104_E	238_R	0.824	0.98
54_N	58_F	0.821	0.98
120_F	133_E	0.817	0.98
94_S	98_Y	0.816	0.98
127_D	203_T	0.814	0.98
34_F	45_F	0.800	0.98
180_Q	183_S	0.800	0.98
55_G	219_E	0.793	0.98
65_N	80_T	0.791	0.98
120_F	208_M	0.788	0.98
134_I	184_I	0.787	0.98
92_N	209_M	0.781	0.98
125_P	203_T	0.781	0.98
60_C	212_W	0.777	0.98
124_G	206_K	0.775	0.98
47_Q	95_V	0.770	0.98
141_K	220_W	0.770	0.98
198_N	202_T	0.761	0.97
125_P	131_W	0.759	0.97
96_Q	124_G	0.758	0.97
50_D	53_S	0.757	0.97
111_K	169_A	0.757	0.97
176_A	190_G	0.753	0.97
23_T	26_A	0.746	0.97
36_D	46_W	0.745	0.97
102_L	187_Y	0.744	0.97
125_P	204_P	0.742	0.97
159_E	165_G	0.741	0.97
103_Y	239_Y	0.741	0.97
27_S	30_T	0.740	0.97
159_E	163_D	0.734	0.97
123_T	201_P	0.732	0.97
153_N	156_G	0.732	0.97
53_S	91_E	0.731	0.97
69_M	76_R	0.730	0.97
82_P	86_K	0.730	0.97
119_F	136_I	0.727	0.97
161_I	165_G	0.723	0.96
118_S	135_D	0.722	0.96
56_N	212_W	0.720	0.96
220_W	228_N	0.718	0.96
160_K	165_G	0.716	0.96
41_Y	67_V	0.716	0.96
49_A	91_E	0.715	0.96
54_N	122_Y	0.713	0.96
207_I	239_Y	0.711	0.96
89_C	212_W	0.706	0.96
63_R	82_P	0.706	0.96
30_T	241_K	0.705	0.96
220_W	224_Y	0.701	0.96
163_D	166_F	0.694	0.95
120_F	210_N	0.693	0.95
103_Y	119_F	0.691	0.95
81_S	226_G	0.689	0.95
186_W	196_A	0.684	0.95
139_L	221_L	0.683	0.95
91_E	132_D	0.682	0.95
98_Y	124_G	0.677	0.95
213_N	224_Y	0.677	0.95
74_E	106_R	0.675	0.95
118_S	210_N	0.672	0.95
61_T	66_N	0.668	0.94
126_T	206_K	0.667	0.94
70_T	231_Y	0.663	0.94
152_T	199_Q	0.660	0.94
91_E	208_M	0.657	0.94
168_A	171_A	0.657	0.94
218_D	221_L	0.655	0.94
33_S	103_Y	0.654	0.94
102_L	236_W	0.654	0.94
134_I	177_F	0.653	0.94
123_T	126_T	0.653	0.94
102_L	240_T	0.649	0.94
188_V	191_Q	0.643	0.93
111_K	170_N	0.640	0.93
73_G	235_D	0.634	0.93
139_L	220_W	0.634	0.93
122_Y	126_T	0.634	0.93
43_S	48_K	0.633	0.93
24_A	27_S	0.629	0.92
95_V	127_D	0.626	0.92
117_S	212_W	0.626	0.92
59_N	62_W	0.625	0.92
100_Y	179_W	0.625	0.92
65_N	82_P	0.625	0.92
109_P	117_S	0.623	0.92
138_F	141_K	0.620	0.92
107_M	175_Y	0.618	0.92
58_F	62_W	0.617	0.92
103_Y	177_F	0.615	0.92
102_L	190_G	0.609	0.91
33_S	239_Y	0.605	0.91
75_M	92_N	0.604	0.91
32_G	238_R	0.602	0.91
152_T	200_I	0.601	0.91
66_N	82_P	0.601	0.91
67_V	77_L	0.601	0.91
34_F	240_T	0.599	0.91
120_F	212_W	0.598	0.90
199_Q	202_T	0.595	0.90
122_Y	206_K	0.595	0.90
37_P	236_W	0.592	0.90
81_S	86_K	0.591	0.90
150_Y	196_A	0.590	0.90
218_D	222_G	0.589	0.90
60_C	89_C	0.589	0.90
113_T	221_L	0.589	0.90
131_W	203_T	0.587	0.90
77_L	211_L	0.585	0.90
79_L	231_Y	0.585	0.90
41_Y	69_M	0.578	0.89
87_F	114_G	0.575	0.89
68_S	231_Y	0.575	0.89
186_W	193_K	0.573	0.89
107_M	234_Y	0.573	0.89
108_K	170_N	0.572	0.88
162_V	166_F	0.572	0.88
104_E	187_Y	0.571	0.88
139_L	142_D	0.569	0.88
60_C	63_R	0.569	0.88
70_T	233_H	0.569	0.88
209_M	232_A	0.568	0.88
102_L	174_T	0.568	0.88
100_Y	203_T	0.566	0.88
58_F	61_T	0.564	0.88
147_Q	220_W	0.563	0.88
75_M	209_M	0.562	0.88
36_D	238_R	0.562	0.88
159_E	164_L	0.560	0.87
160_K	164_L	0.559	0.87
113_T	223_S	0.559	0.87
105_V	236_W	0.556	0.87
172_Y	175_Y	0.555	0.87
172_Y	235_D	0.554	0.87
24_A	28_A	0.554	0.87
43_S	97_T	0.554	0.87
135_D	151_Y	0.553	0.87
218_D	223_S	0.553	0.87
219_E	223_S	0.553	0.87
128_G	131_W	0.552	0.87
51_G	55_G	0.548	0.86
141_K	221_L	0.547	0.86
153_N	200_I	0.546	0.86
98_Y	103_Y	0.545	0.86
51_G	54_N	0.545	0.86
165_G	168_A	0.542	0.86
54_N	60_C	0.540	0.85
79_L	89_C	0.539	0.85
223_S	227_V	0.539	0.85
152_T	156_G	0.535	0.85
91_E	212_W	0.535	0.85
25_T	28_A	0.534	0.85
182_N	198_N	0.534	0.85
167_D	171_A	0.533	0.85
151_Y	154_G	0.532	0.85
63_R	83_A	0.530	0.84
113_T	141_K	0.525	0.84
148_F	152_T	0.523	0.84
117_S	210_N	0.521	0.83
112_N	227_V	0.519	0.83
120_F	135_D	0.519	0.83
115_I	138_F	0.518	0.83
210_N	214_G	0.517	0.83
221_L	228_N	0.517	0.83
30_T	33_S	0.516	0.83
43_S	62_W	0.515	0.83
67_V	75_M	0.512	0.82
166_F	170_N	0.512	0.82
64_A	90_G	0.511	0.82
112_N	230_L	0.511	0.82
127_D	131_W	0.510	0.82
64_A	67_V	0.509	0.82
109_P	146_V	0.509	0.82
115_I	228_N	0.508	0.82
60_C	210_N	0.507	0.82
132_D	214_G	0.506	0.82
114_G	214_G	0.505	0.82
116_V	208_M	0.504	0.81
176_A	186_W	0.501	0.81
123_T	206_K	0.501	0.81
112_N	140_G	0.500	0.81
116_V	137_E	0.500	0.81

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3o5sA	1	0.8802	100	0.168	Contact Map
3wvjA	1	0.8843	100	0.195	Contact Map
3i4iA	1	0.876	100	0.199	Contact Map
2ayhA	1	0.8843	100	0.202	Contact Map
3ilnA	1	0.8802	100	0.219	Contact Map
1upsA	1	0.8926	100	0.224	Contact Map
4bpzA	1	0.8843	100	0.23	Contact Map
3juuA	1	0.9174	100	0.231	Contact Map
3azyA	1	0.8636	100	0.235	Contact Map
2hykA	1	0.8595	100	0.24	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0079 seconds.