GREMLIN Database
SSPB - Small, acid-soluble spore protein B
UniProt: P04832 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 67 (60)
Sequences: 501 (205)
Seq/√Len: 26.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
51_T54_L3.6431.00
45_S49_E3.1231.00
43_N46_V2.5910.99
50_I54_L2.3420.98
56_S60_Q2.2470.98
49_E52_K2.2340.98
51_T55_V2.1510.97
39_T42_A1.9440.95
22_M26_I1.9310.95
30_F49_E1.8980.94
35_G38_T1.7200.91
26_I53_R1.7050.90
18_A22_M1.5730.86
16_A20_D1.4980.83
57_F60_Q1.4910.83
40_S43_N1.4610.82
32_V46_V1.3870.78
45_S52_K1.2560.71
34_L45_S1.2430.70
19_I50_I1.2220.69
50_I64_G1.2170.68
19_I55_V1.1490.64
49_E56_S1.1240.62
35_G43_N1.1240.62
38_T43_N1.0910.60
32_V38_T1.0440.56
49_E53_R1.0350.56
22_M58_A0.9830.52
35_G46_V0.9710.51
14_G60_Q0.9630.50
26_I46_V0.9390.48
57_F61_Q0.9150.47
34_L43_N0.9070.46
12_V61_Q0.8980.45
29_E53_R0.8960.45
24_L50_I0.8780.44
26_I52_K0.8730.43
37_D55_V0.8510.42
28_S36_A0.8230.40
17_Q59_Q0.7960.38
15_A22_M0.7910.38
24_L29_E0.7820.37
32_V35_G0.7770.37
6_S59_Q0.7730.36
61_Q64_G0.7680.36
15_A28_S0.7660.36
59_Q62_M0.7620.36
10_L36_A0.7590.35
14_G56_S0.7580.35
15_A37_D0.7570.35
54_L58_A0.7360.34
16_A19_I0.7330.34
10_L13_P0.7330.34
29_E40_S0.7020.32
17_Q33_N0.7010.32
55_V58_A0.6870.31
26_I49_E0.6850.30
15_A18_A0.6840.30
8_N62_M0.6720.30
40_S52_K0.6660.29
10_L57_F0.6490.28
41_R58_A0.6470.28
16_A53_R0.6460.28
9_D12_V0.6460.28
58_A62_M0.6360.27
30_F45_S0.6260.27
20_D38_T0.6180.26
35_G40_S0.6170.26
45_S64_G0.5950.25
26_I30_F0.5910.25
41_R46_V0.5910.25
11_L19_I0.5870.25
12_V57_F0.5850.25
5_N22_M0.5720.24
34_L37_D0.5680.24
21_Q64_G0.5590.23
11_L41_R0.5490.23
52_K60_Q0.5480.23
9_D13_P0.5470.23
22_M55_V0.5440.22
10_L14_G0.5440.22
5_N9_D0.5430.22
34_L42_A0.5420.22
11_L21_Q0.5360.22
41_R56_S0.5270.21
32_V37_D0.5270.21
46_V49_E0.5210.21
19_I54_L0.5060.20
37_D56_S0.5000.20
16_A28_S0.5000.20
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2z3xA 3 0.8358 99.9 0.301 Contact Map
3k44A 1 0.4627 12.3 0.912 Contact Map
4bzjA 2 0 8.6 0.918 Contact Map
3frrA 1 0.6567 6.7 0.922 Contact Map
3ggyA 1 0.6119 6.3 0.923 Contact Map
2qb7A 1 0.3582 5.6 0.925 Contact Map
3tviA 2 0.9403 3.8 0.93 Contact Map
4wz4A 1 0.3433 3.1 0.933 Contact Map
3h0gA 2 0.9851 3 0.934 Contact Map
1j5pA 2 0.8507 2.9 0.934 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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