GREMLIN Database
AMY - Alpha-amylase
UniProt: P00691 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 659 (547)
Sequences: 996 (776)
Seq/√Len: 33.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
129_E212_D7.6241.00
579_Y582_K4.5161.00
71_H131_Y4.1631.00
127_A130_E3.6721.00
61_N64_K3.4851.00
117_T120_E3.2631.00
170_N173_D3.2191.00
64_K123_E3.1881.00
61_N120_E3.0841.00
579_Y584_D2.9421.00
118_E205_R2.8511.00
492_T495_L2.8351.00
161_W164_G2.6081.00
575_Q581_Y2.5711.00
332_A460_V2.5471.00
127_A131_Y2.4951.00
567_Y571_N2.4821.00
126_A130_E2.4541.00
575_Q582_K2.4431.00
542_N546_V2.4340.99
485_H488_N2.3780.99
268_T273_G2.3770.99
577_N581_Y2.3500.99
581_Y584_D2.3490.99
491_L495_L2.3010.99
566_G569_N2.2960.99
503_K506_Y2.2940.99
70_I75_Y2.2870.99
68_K131_Y2.2780.99
64_K127_A2.2770.99
582_K585_G2.2720.99
160_N164_G2.2710.99
119_Q123_E2.2680.99
575_Q579_Y2.2270.99
579_Y597_G2.2000.99
557_R562_A2.1400.99
188_W195_V2.1290.99
370_L373_D2.1060.99
430_L433_G2.1000.98
576_V579_Y2.0980.98
280_L333_V2.0440.98
353_N357_F2.0270.98
147_D151_I2.0070.98
365_D373_D2.0000.98
501_T504_A1.9980.98
557_R565_I1.9840.98
136_I213_G1.9620.98
579_Y583_H1.9580.98
149_A152_S1.9400.97
572_H582_K1.9050.97
534_Y540_G1.8920.97
366_R369_A1.8780.97
582_K586_S1.8550.97
369_A373_D1.8540.97
553_S556_K1.8520.97
437_N441_A1.8500.97
200_K233_Q1.8190.96
564_T568_Q1.7950.96
148_Y151_I1.7770.96
581_Y585_G1.7700.96
577_N585_G1.7640.95
581_Y586_S1.7600.95
576_V581_Y1.7580.95
552_Y556_K1.7550.95
69_D73_A1.7400.95
488_N495_L1.7280.95
572_H578_A1.7160.95
85_Q88_E1.7130.95
507_Q510_N1.7090.95
270_S273_G1.7000.94
577_N582_K1.6980.94
352_G357_F1.6930.94
572_H585_G1.6760.94
485_H495_L1.6760.94
85_Q110_I1.6690.94
573_W576_V1.6600.94
550_E554_F1.6540.94
269_A273_G1.6530.94
122_K209_D1.6490.93
61_N65_H1.6440.93
493_I497_A1.6400.93
147_D152_S1.6280.93
576_V585_G1.6200.93
565_I571_N1.6110.93
147_D153_N1.6080.93
307_E347_R1.6070.93
437_N440_G1.6050.92
102_L115_L1.5960.92
474_V479_Y1.5940.92
488_N493_I1.5910.92
125_C135_V1.5890.92
146_S186_Y1.5800.92
503_K508_I1.5680.92
82_P90_N1.5530.91
81_S115_L1.5500.91
565_I568_Q1.5490.91
365_D370_L1.5440.91
430_L435_Y1.5350.91
84_N105_P1.5350.91
176_D179_Q1.5320.91
579_Y585_G1.5290.91
576_V582_K1.5200.90
148_Y152_S1.5200.90
485_H489_D1.5170.90
581_Y596_P1.5160.90
557_R567_Y1.4960.90
534_Y538_L1.4900.89
573_W585_G1.4870.89
561_S565_I1.4870.89
61_N123_E1.4860.89
128_A135_V1.4750.89
562_A567_Y1.4730.89
119_Q122_K1.4630.88
135_V212_D1.4600.88
475_F478_N1.4560.88
573_W581_Y1.4550.88
531_G534_Y1.4450.88
414_L455_I1.4440.88
179_Q182_L1.4350.87
432_D435_Y1.4300.87
149_A154_E1.4300.87
67_M131_Y1.4280.87
551_K555_V1.4280.87
562_A565_I1.4270.87
54_H81_S1.4260.87
578_A582_K1.4190.87
575_Q585_G1.4180.87
577_N580_I1.4170.87
567_Y570_P1.4080.86
121_F137_V1.4050.86
578_A583_H1.3990.86
604_A607_I1.3990.86
559_P570_P1.3990.86
597_G601_T1.3890.86
565_I569_N1.3780.85
100_Y104_Q1.3770.85
572_H576_V1.3550.84
579_Y596_P1.3550.84
516_F520_D1.3500.84
78_I128_A1.3480.84
67_M124_M1.3440.84
561_S568_Q1.3400.84
187_D220_K1.3370.83
425_N452_T1.3320.83
557_R563_K1.3300.83
49_S390_P1.3300.83
360_K363_I1.3220.83
361_S364_G1.3170.82
255_A258_D1.3120.82
62_T69_D1.3120.82
369_A372_E1.3110.82
197_S201_R1.3100.82
597_G600_M1.3010.82
566_G581_Y1.3010.82
474_V481_T1.2930.81
501_T506_Y1.2900.81
578_A581_Y1.2880.81
578_A600_M1.2850.81
315_D327_I1.2830.81
44_A48_K1.2820.81
557_R570_P1.2800.81
331_W347_R1.2800.81
500_N503_K1.2760.80
150_A154_E1.2700.80
352_G355_V1.2690.80
495_L500_N1.2650.80
481_T484_T1.2630.80
176_D180_N1.2610.80
99_W104_Q1.2560.79
576_V583_H1.2330.78
447_N450_K1.2290.78
578_A584_D1.2270.78
560_A567_Y1.2260.78
428_T459_S1.2240.78
569_N576_V1.2170.77
579_Y586_S1.2140.77
577_N584_D1.2120.77
562_A571_N1.2120.77
121_F211_A1.2110.77
353_N356_R1.2100.77
550_E555_V1.2100.77
148_Y153_N1.2090.77
566_G607_I1.2080.77
456_N459_S1.2070.77
83_I121_F1.2060.76
359_G362_Q1.2060.76
568_Q571_N1.2060.76
175_W179_Q1.2050.76
583_H586_S1.2050.76
551_K554_F1.2000.76
572_H579_Y1.2000.76
269_A338_S1.2000.76
489_D495_L1.2000.76
566_G571_N1.1920.76
557_R568_Q1.1910.76
579_Y595_W1.1900.75
551_K561_S1.1880.75
434_R442_G1.1860.75
487_F495_L1.1830.75
566_G570_P1.1810.75
85_Q89_G1.1770.75
86_V89_G1.1730.74
487_F493_I1.1680.74
212_D348_P1.1640.74
557_R561_S1.1640.74
151_I154_E1.1630.74
128_A133_I1.1610.74
558_D563_K1.1610.74
504_A507_Q1.1590.74
499_A504_A1.1580.73
507_Q511_G1.1570.73
603_N606_G1.1450.73
222_I227_D1.1430.72
562_A566_G1.1400.72
576_V586_S1.1380.72
175_W178_T1.1360.72
366_R373_D1.1360.72
149_A153_N1.1330.72
564_T570_P1.1330.72
583_H596_P1.1330.72
58_W62_T1.1310.72
141_I216_F1.1310.72
59_S101_W1.1300.72
572_H575_Q1.1290.72
218_A227_D1.1290.72
53_L58_W1.1250.71
519_G522_F1.1230.71
602_K605_D1.1180.71
103_Y138_D1.1160.71
572_H581_Y1.1160.71
52_I77_A1.1100.70
500_N508_I1.1100.70
386_M411_G1.1090.70
577_N596_P1.1090.70
494_T500_N1.1070.70
204_D233_Q1.1060.70
581_Y600_M1.1020.70
560_A569_N1.1020.70
572_H584_D1.1000.70
54_H218_A1.0990.69
574_S581_Y1.0960.69
603_N607_I1.0960.69
575_Q583_H1.0950.69
569_N572_H1.0910.69
549_T554_F1.0900.69
391_E395_N1.0900.69
358_P361_S1.0880.69
54_H79_Q1.0860.69
569_N573_W1.0850.68
58_W101_W1.0830.68
485_H492_T1.0830.68
558_D565_I1.0820.68
143_H309_H1.0810.68
419_S458_R1.0810.68
572_H577_N1.0800.68
217_D310_D1.0780.68
215_R310_D1.0780.68
54_H101_W1.0740.68
129_E135_V1.0730.68
563_K580_I1.0710.67
602_K607_I1.0710.67
353_N358_P1.0700.67
270_S305_W1.0700.67
491_L525_G1.0680.67
572_H583_H1.0650.67
569_N600_M1.0650.67
177_V183_L1.0620.67
139_A214_F1.0620.67
559_P562_A1.0610.67
249_E310_D1.0600.67
305_W308_S1.0570.66
509_N513_E1.0530.66
82_P88_E1.0520.66
85_Q90_N1.0520.66
576_V584_D1.0510.66
490_Q495_L1.0490.66
558_D569_N1.0480.66
55_A63_L1.0470.66
169_K173_D1.0470.66
54_H268_T1.0470.66
574_S579_Y1.0430.65
80_T83_I1.0390.65
303_V340_S1.0370.65
258_D264_Y1.0370.65
575_Q584_D1.0350.65
336_S405_N1.0350.65
187_D261_Y1.0310.64
562_A569_N1.0300.64
431_P435_Y1.0290.64
79_Q305_W1.0240.64
433_G446_V1.0240.64
353_N361_S1.0220.64
580_I586_S1.0190.63
144_T188_W1.0180.63
580_I607_I1.0170.63
140_V143_H1.0160.63
54_H58_W1.0160.63
207_L241_T1.0150.63
105_P202_F1.0140.63
161_W192_N1.0130.63
558_D561_S1.0120.63
148_Y154_E1.0110.63
124_M128_A1.0100.63
569_N581_Y1.0100.63
168_I171_W1.0090.63
513_E520_D1.0090.63
600_M604_A1.0070.63
123_E127_A1.0070.63
413_V462_V1.0060.62
290_I293_Y0.9990.62
102_L309_H0.9990.62
568_Q573_W0.9950.62
570_P579_Y0.9950.62
217_D249_E0.9920.61
215_R249_E0.9920.61
260_A264_Y0.9910.61
288_S292_H0.9850.61
261_Y265_M0.9850.61
566_G576_V0.9790.60
563_K566_G0.9770.60
558_D562_A0.9750.60
511_G525_G0.9750.60
564_T567_Y0.9710.60
56_W81_S0.9700.60
536_I542_N0.9690.60
573_W577_N0.9660.59
87_K90_N0.9660.59
577_N597_G0.9650.59
521_Q527_G0.9650.59
355_V358_P0.9580.59
247_Y268_T0.9580.59
481_T485_H0.9570.59
73_A348_P0.9560.58
203_L214_F0.9530.58
273_G311_T0.9530.58
487_F490_Q0.9430.57
381_R384_N0.9410.57
573_W578_A0.9380.57
121_F125_C0.9380.57
82_P85_Q0.9350.57
485_H491_L0.9340.57
391_E394_S0.9310.56
572_H605_D0.9300.56
86_V101_W0.9280.56
54_H104_Q0.9270.56
491_L497_A0.9260.56
177_V180_N0.9250.56
572_H586_S0.9240.56
503_K507_Q0.9230.56
573_W579_Y0.9210.56
414_L461_A0.9190.55
64_K120_E0.9190.55
509_N514_T0.9180.55
568_Q583_H0.9180.55
550_E553_S0.9170.55
66_N69_D0.9170.55
566_G573_W0.9160.55
423_S452_T0.9150.55
534_Y537_M0.9130.55
59_S62_T0.9120.55
53_L60_F0.9110.55
120_E214_F0.9100.55
492_T497_A0.9080.55
557_R564_T0.9050.54
79_Q269_A0.9040.54
583_H607_I0.9040.54
200_K229_S0.9030.54
597_G602_K0.9010.54
539_K545_G0.8980.54
202_F206_A0.8980.54
558_D567_Y0.8950.53
500_N504_A0.8930.53
524_I540_G0.8910.53
477_E481_T0.8850.53
562_A573_W0.8840.53
576_V580_I0.8790.52
510_N514_T0.8790.52
554_F561_S0.8770.52
600_M603_N0.8750.52
586_S605_D0.8740.52
564_T572_H0.8700.51
418_G426_T0.8690.51
501_T505_V0.8680.51
595_W600_M0.8670.51
433_G436_D0.8640.51
505_V508_I0.8620.51
570_P575_Q0.8610.51
103_Y310_D0.8610.51
421_S454_T0.8600.51
556_K559_P0.8590.50
229_S233_Q0.8590.50
494_T497_A0.8580.50
341_T383_H0.8560.50
326_D458_R0.8550.50
218_A221_H0.8540.50
474_V477_E0.8540.50
104_Q219_A0.8520.50
288_S293_Y0.8510.50
571_N581_Y0.8510.50
595_W601_T0.8500.50
573_W604_A0.8500.50
241_T244_E0.8490.50
47_I136_I0.8490.50
601_T606_G0.8470.49
84_N108_Y0.8460.49
580_I584_D0.8440.49
365_D372_E0.8430.49
493_I496_R0.8410.49
160_N163_H0.8400.49
174_R178_T0.8400.49
479_Y488_N0.8390.49
204_D234_F0.8390.49
580_I585_G0.8380.49
570_P581_Y0.8370.49
179_Q183_L0.8370.49
492_T496_R0.8350.48
169_K172_S0.8340.48
196_Q199_L0.8330.48
423_S454_T0.8300.48
600_M606_G0.8300.48
150_A153_N0.8290.48
571_N600_M0.8270.48
526_K535_T0.8270.48
319_S322_M0.8270.48
287_V291_S0.8260.48
67_M72_D0.8260.48
289_N292_H0.8250.48
216_F230_Y0.8240.48
117_T196_Q0.8220.47
500_N505_V0.8200.47
116_G407_R0.8200.47
79_Q270_S0.8190.47
180_N183_L0.8170.47
575_Q586_S0.8170.47
79_Q268_T0.8130.47
563_K569_N0.8130.47
120_E123_E0.8130.47
561_S569_N0.8100.46
581_Y595_W0.8060.46
79_Q107_S0.8040.46
561_S567_Y0.8030.46
484_T491_L0.8010.46
173_D177_V0.8000.46
252_Q257_R0.7970.45
430_L436_D0.7960.45
260_A265_M0.7950.45
103_Y215_R0.7940.45
103_Y217_D0.7940.45
119_Q525_G0.7940.45
581_Y606_G0.7930.45
145_T186_Y0.7920.45
220_K227_D0.7910.45
520_D526_K0.7880.45
479_Y492_T0.7850.44
571_N585_G0.7820.44
527_G545_G0.7790.44
169_K176_D0.7780.44
54_H342_P0.7770.44
359_G364_G0.7740.43
585_G596_P0.7730.43
559_P566_G0.7710.43
479_Y485_H0.7700.43
574_S583_H0.7670.43
325_D415_A0.7670.43
493_I504_A0.7640.43
491_L570_P0.7630.43
585_G605_D0.7620.42
53_L62_T0.7610.42
567_Y576_V0.7590.42
510_N513_E0.7580.42
482_G489_D0.7570.42
53_L348_P0.7570.42
581_Y603_N0.7560.42
488_N492_T0.7560.42
560_A566_G0.7560.42
573_W583_H0.7540.42
269_A304_T0.7540.42
485_H496_R0.7540.42
526_K534_Y0.7540.42
585_G603_N0.7530.42
416_N456_N0.7530.42
446_V451_L0.7530.42
551_K557_R0.7520.42
576_V606_G0.7500.41
583_H597_G0.7470.41
577_N586_S0.7440.41
289_N447_N0.7440.41
569_N579_Y0.7430.41
81_S86_V0.7430.41
397_N422_V0.7420.41
207_L244_E0.7420.41
573_W596_P0.7420.41
563_K568_Q0.7410.41
564_T580_I0.7400.41
420_S457_A0.7400.41
557_R560_A0.7390.41
368_S373_D0.7390.41
260_A266_D0.7370.40
585_G606_G0.7360.40
367_G372_E0.7360.40
560_A565_I0.7340.40
38_K41_E0.7330.40
554_F560_A0.7330.40
596_P600_M0.7320.40
490_Q497_A0.7310.40
103_Y249_E0.7310.40
479_Y482_G0.7300.40
53_L346_S0.7290.40
60_F66_N0.7290.40
428_T435_Y0.7260.40
189_N192_N0.7260.40
352_G358_P0.7260.40
470_K474_V0.7250.39
575_Q578_A0.7250.39
565_I570_P0.7250.39
571_N578_A0.7220.39
576_V596_P0.7210.39
573_W580_I0.7210.39
79_Q102_L0.7210.39
564_T606_G0.7200.39
170_N176_D0.7200.39
554_F557_R0.7200.39
396_P400_N0.7190.39
253_D265_M0.7170.39
451_L555_V0.7170.39
53_L70_I0.7150.39
601_T604_A0.7150.39
329_L460_V0.7140.39
489_D493_I0.7130.38
573_W586_S0.7130.38
519_G540_G0.7120.38
434_R447_N0.7100.38
79_Q101_W0.7090.38
568_Q572_H0.7090.38
484_T495_L0.7090.38
359_G363_I0.7090.38
153_N157_S0.7080.38
572_H606_G0.7080.38
580_I583_H0.7080.38
85_Q100_Y0.7080.38
79_Q104_Q0.7040.38
190_T221_H0.7010.38
348_P360_K0.6990.37
551_K556_K0.6990.37
552_Y555_V0.6960.37
559_P567_Y0.6960.37
573_W582_K0.6950.37
58_W79_Q0.6950.37
318_E322_M0.6930.37
102_L105_P0.6920.37
549_T552_Y0.6900.37
504_A509_N0.6890.37
331_W376_I0.6890.37
515_A520_D0.6870.36
569_N574_S0.6860.36
511_G519_G0.6850.36
560_A564_T0.6840.36
104_Q218_A0.6830.36
86_V145_T0.6830.36
577_N583_H0.6810.36
187_D221_H0.6800.36
142_N187_D0.6800.36
210_G407_R0.6790.36
118_E209_D0.6790.36
567_Y572_H0.6770.36
188_W199_L0.6770.36
576_V602_K0.6760.36
506_Y509_N0.6760.36
220_K252_Q0.6730.35
413_V416_N0.6710.35
115_L309_H0.6690.35
406_Q410_H0.6680.35
602_K606_G0.6680.35
396_P401_Q0.6640.35
141_I227_D0.6620.35
116_G313_A0.6610.34
526_K536_I0.6610.34
486_S493_I0.6600.34
566_G604_A0.6590.34
578_A585_G0.6550.34
174_R177_V0.6540.34
54_H102_L0.6540.34
69_D348_P0.6530.34
560_A568_Q0.6510.34
234_F330_G0.6500.34
353_N360_K0.6480.33
566_G578_A0.6470.33
137_V206_A0.6460.33
60_F113_R0.6460.33
569_N585_G0.6450.33
499_A506_Y0.6450.33
568_Q606_G0.6440.33
560_A570_P0.6430.33
507_Q535_T0.6390.33
70_I111_G0.6390.33
102_L129_E0.6390.33
520_D551_K0.6380.33
225_P229_S0.6380.33
73_A377_T0.6360.33
219_A250_I0.6360.33
345_F348_P0.6340.32
345_F351_G0.6340.32
476_L479_Y0.6340.32
174_R183_L0.6340.32
576_V600_M0.6310.32
105_P378_A0.6300.32
58_W73_A0.6290.32
559_P563_K0.6290.32
366_R370_L0.6270.32
542_N545_G0.6260.32
436_D439_A0.6260.32
430_L437_N0.6260.32
446_V449_G0.6260.32
313_A338_S0.6240.32
596_P601_T0.6230.32
60_F304_T0.6230.32
177_V182_L0.6230.32
432_D448_D0.6220.32
111_G216_F0.6220.32
318_E323_S0.6220.32
549_T555_V0.6210.32
472_P475_F0.6210.32
57_N83_I0.6210.32
82_P216_F0.6200.31
581_Y597_G0.6200.31
529_P535_T0.6200.31
308_S313_A0.6190.31
581_Y607_I0.6170.31
258_D266_D0.6170.31
563_K574_S0.6170.31
551_K560_A0.6150.31
368_S372_E0.6120.31
219_A248_G0.6120.31
68_K72_D0.6120.31
475_F479_Y0.6110.31
302_L305_W0.6110.31
130_E537_M0.6110.31
471_A532_K0.6110.31
196_Q226_D0.6100.31
126_A443_S0.6100.31
199_L222_I0.6090.31
578_A586_S0.6080.31
263_N266_D0.6070.31
358_P363_I0.6050.30
550_E557_R0.6040.30
565_I607_I0.6030.30
289_N293_Y0.6030.30
111_G115_L0.6020.30
434_R445_Q0.6010.30
571_N576_V0.6010.30
565_I572_H0.6000.30
76_T309_H0.5990.30
497_A508_I0.5990.30
178_T182_L0.5980.30
557_R571_N0.5970.30
570_P574_S0.5970.30
431_P436_D0.5960.30
562_A572_H0.5960.30
79_Q187_D0.5940.30
572_H603_N0.5930.30
483_V493_I0.5930.30
236_P477_E0.5910.29
485_H493_I0.5910.29
268_T272_Y0.5900.29
556_K561_S0.5890.29
112_N244_E0.5890.29
289_N434_R0.5890.29
247_Y303_V0.5890.29
116_G344_F0.5890.29
500_N506_Y0.5880.29
571_N584_D0.5870.29
102_L206_A0.5870.29
321_W324_D0.5870.29
162_T336_S0.5860.29
287_V290_I0.5860.29
421_S456_N0.5860.29
533_T542_N0.5850.29
124_M306_V0.5850.29
86_V218_A0.5840.29
79_Q304_T0.5840.29
517_K520_D0.5830.29
325_D458_R0.5830.29
595_W604_A0.5830.29
62_T360_K0.5820.29
81_S102_L0.5810.29
59_S104_Q0.5800.29
565_I606_G0.5790.29
571_N577_N0.5790.29
576_V604_A0.5790.29
425_N457_A0.5780.28
549_T604_A0.5780.28
58_W99_W0.5780.28
445_Q448_D0.5780.28
535_T540_G0.5770.28
559_P575_Q0.5770.28
601_T605_D0.5750.28
253_D264_Y0.5740.28
54_H344_F0.5730.28
168_I176_D0.5720.28
58_W81_S0.5720.28
566_G577_N0.5710.28
268_T342_P0.5700.28
488_N497_A0.5700.28
64_K457_A0.5700.28
50_G134_K0.5690.28
557_R566_G0.5690.28
55_A66_N0.5680.28
53_L101_W0.5670.28
564_T576_V0.5660.28
550_E560_A0.5650.28
174_R180_N0.5650.28
125_C137_V0.5640.28
230_Y294_A0.5630.27
490_Q496_R0.5630.27
216_F234_F0.5620.27
521_Q524_I0.5610.27
147_D154_E0.5610.27
58_W104_Q0.5600.27
571_N601_T0.5600.27
550_E556_K0.5590.27
481_T487_F0.5590.27
420_S423_S0.5580.27
319_S323_S0.5580.27
67_M133_I0.5570.27
556_K562_A0.5560.27
428_T431_P0.5550.27
559_P568_Q0.5550.27
563_K582_K0.5550.27
189_N303_V0.5550.27
70_I78_I0.5540.27
311_T314_N0.5540.27
255_A260_A0.5530.27
320_T324_D0.5530.27
82_P100_Y0.5530.27
87_K100_Y0.5520.27
382_F386_M0.5520.27
511_G541_T0.5520.27
367_G373_D0.5520.27
571_N574_S0.5510.27
484_T497_A0.5500.27
365_D368_S0.5500.27
584_D600_M0.5480.26
382_F462_V0.5470.26
50_G77_A0.5460.26
574_S586_S0.5460.26
190_T220_K0.5450.26
522_F539_K0.5450.26
261_Y266_D0.5440.26
384_N433_G0.5440.26
54_H303_V0.5430.26
491_L496_R0.5430.26
64_K124_M0.5420.26
40_N43_T0.5410.26
172_S175_W0.5410.26
122_K126_A0.5410.26
487_F491_L0.5400.26
101_W268_T0.5390.26
392_E395_N0.5390.26
252_Q311_T0.5390.26
515_A528_D0.5390.26
494_T506_Y0.5370.26
495_L506_Y0.5360.26
567_Y581_Y0.5360.26
98_N101_W0.5350.26
215_R309_H0.5320.25
217_D309_H0.5320.25
476_L483_V0.5320.25
571_N607_I0.5310.25
60_F346_S0.5300.25
443_S446_V0.5290.25
492_T533_T0.5280.25
502_T505_V0.5280.25
86_V114_Y0.5280.25
82_P87_K0.5280.25
532_K539_K0.5280.25
574_S595_W0.5270.25
258_D271_N0.5270.25
531_G539_K0.5260.25
562_A568_Q0.5250.25
476_L485_H0.5240.25
328_R375_A0.5230.25
520_D539_K0.5230.25
504_A508_I0.5220.25
58_W360_K0.5220.25
210_G223_E0.5220.25
438_K445_Q0.5220.25
216_F246_Q0.5220.25
53_L73_A0.5200.25
566_G572_H0.5190.25
119_Q425_N0.5190.25
55_A139_A0.5190.25
551_K570_P0.5170.25
559_P569_N0.5170.25
249_E309_H0.5170.25
366_R372_E0.5170.25
270_S308_S0.5150.24
484_T488_N0.5150.24
62_T348_P0.5130.24
575_Q601_T0.5120.24
484_T489_D0.5110.24
555_V560_A0.5100.24
127_A135_V0.5100.24
161_W194_Q0.5100.24
129_E346_S0.5090.24
397_N400_N0.5090.24
358_P364_G0.5080.24
86_V102_L0.5080.24
479_Y496_R0.5070.24
54_H309_H0.5060.24
367_G370_L0.5060.24
73_A403_F0.5050.24
584_D605_D0.5050.24
586_S596_P0.5030.24
159_P455_I0.5030.24
53_L102_L0.5030.24
54_H216_F0.5020.24
543_S546_V0.5010.24
596_P607_I0.5010.24
213_G336_S0.5010.24
62_T346_S0.5000.23
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1qhoA 1 0.9059 100 0.392 Contact Map
4jcmA 1 0.9059 100 0.393 Contact Map
1d3cA 1 0.9165 100 0.399 Contact Map
1cygA 1 0.9135 100 0.4 Contact Map
4jclA 1 0.9196 100 0.403 Contact Map
3bmvA 1 0.915 100 0.403 Contact Map
1ua7A 1 0.6313 100 0.453 Contact Map
1jaeA 1 0.6404 100 0.46 Contact Map
4e2oA 1 0.6237 100 0.462 Contact Map
1g94A 1 0.6191 100 0.469 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0149 seconds.