GREMLIN Database
RELA - GTP pyrophosphokinase
UniProt: O54408 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 734 (702)
Sequences: 3426 (1942)
Seq/√Len: 73.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
91_K96_E7.2381.00
497_V536_V5.4001.00
417_Y425_N5.3161.00
433_N447_D4.9381.00
432_V437_V4.7761.00
717_V729_V4.6271.00
413_I467_L4.4441.00
66_M139_L4.3301.00
235_K273_N4.2931.00
30_K93_A4.2501.00
80_V87_L4.1961.00
274_S277_D3.8241.00
468_A477_I3.7641.00
150_R186_E3.7621.00
273_N330_F3.6961.00
27_F72_A3.6541.00
271_L330_F3.6031.00
237_D330_F3.5931.00
228_R231_E3.4491.00
28_V71_I3.4061.00
69_S97_E3.2941.00
668_R674_E3.2901.00
225_V285_I3.2341.00
157_Q160_Q3.1591.00
165_N169_E2.9561.00
432_V441_H2.9421.00
423_I453_T2.9131.00
526_F535_A2.8941.00
257_K262_I2.8891.00
152_L194_Y2.8831.00
239_S333_H2.8811.00
220_E319_K2.7111.00
203_I245_I2.6831.00
490_V534_A2.6771.00
202_R206_L2.6671.00
16_A28_V2.6521.00
37_D40_R2.6471.00
442_K469_Q2.6071.00
196_N199_Q2.6001.00
663_I720_I2.5741.00
34_Y85_V2.5581.00
610_D626_E2.5481.00
206_L259_F2.5411.00
623_V643_V2.4481.00
494_R533_Y2.4201.00
689_V703_M2.4071.00
87_L103_D2.4021.00
61_L70_T2.3771.00
80_V90_L2.3681.00
29_E33_L2.3641.00
443_L449_V2.3381.00
661_I717_V2.3281.00
226_K230_E2.3051.00
470_T473_A2.2791.00
660_E704_A2.2681.00
398_T404_I2.2651.00
89_D92_E2.2621.00
101_L140_I2.2511.00
157_Q161_R2.2471.00
281_V284_I2.1941.00
665_G671_L2.1871.00
58_A71_I2.1521.00
490_V530_E2.1471.00
273_N277_D2.1461.00
431_K450_E2.1111.00
210_K213_E2.1081.00
217_Y317_G2.1071.00
100_M133_Q2.1061.00
521_A529_E2.0951.00
155_L163_I2.0531.00
616_T622_S2.0461.00
705_I716_V2.0181.00
270_I281_V2.0061.00
410_S470_T2.0051.00
27_F30_K2.0011.00
227_K231_E1.9921.00
66_M70_T1.9721.00
528_N531_D1.9671.00
612_V631_V1.9581.00
216_L220_E1.9541.00
276_K280_A1.9321.00
684_T712_H1.9201.00
160_Q194_Y1.9201.00
330_F334_E1.8751.00
272_V281_V1.8731.00
68_P72_A1.8611.00
45_K155_L1.8601.00
149_M187_L1.8411.00
221_V323_L1.8381.00
222_V226_K1.8351.00
223_N227_K1.8231.00
152_L163_I1.8101.00
87_L91_K1.8071.00
412_P430_A1.8041.00
217_Y318_P1.7951.00
164_S191_A1.7941.00
277_D280_A1.7851.00
61_L74_G1.7821.00
199_Q202_R1.7751.00
441_H444_R1.7661.00
33_L36_E1.7611.00
78_D82_D1.7581.00
218_V240_G1.7431.00
396_V443_L1.7281.00
526_F532_M1.7261.00
211_R242_P1.7221.00
27_F69_S1.7081.00
663_I703_M1.7071.00
19_Y65_E1.7061.00
207_M245_I1.7001.00
441_H447_D1.6961.00
88_D91_K1.6941.00
15_K63_D1.6941.00
421_S425_N1.6871.00
185_W244_H1.6811.00
27_F98_V1.6741.00
87_L99_A1.6661.00
72_A98_V1.6571.00
529_E533_Y1.6541.00
409_G442_K1.6381.00
223_N226_K1.6361.00
152_L164_S1.6311.00
485_R488_E1.6301.00
88_D92_E1.6291.00
215_E219_D1.6220.99
201_Y204_V1.6090.99
228_R288_C1.6080.99
454_S457_S1.6000.99
209_K321_D1.5930.99
35_A51_I1.5930.99
73_G101_L1.5900.99
185_W211_R1.5880.99
412_P432_V1.5560.99
497_V533_Y1.5510.99
91_K99_A1.5500.99
679_V703_M1.5470.99
590_K642_P1.5390.99
667_D699_A1.5380.99
80_V103_D1.5380.99
82_D106_T1.5380.99
26_A30_K1.5350.99
192_L245_I1.5280.99
87_L100_M1.5270.99
486_R531_D1.5210.99
534_A537_G1.5200.99
413_I468_A1.5190.99
668_R671_L1.5090.99
80_V106_T1.4900.99
192_L196_N1.4900.99
672_L689_V1.4880.99
295_R314_T1.4800.99
371_F375_S1.4610.99
78_D81_E1.4570.99
82_D148_N1.4560.99
219_D222_V1.4510.99
80_V99_A1.4500.99
224_E289_W1.4500.99
168_L246_Y1.4410.99
34_Y93_A1.4360.99
719_R722_Q1.4230.99
148_N151_T1.4220.99
16_A20_L1.4190.99
149_M190_T1.4180.99
89_D93_A1.4150.99
418_R472_Q1.3990.98
60_I150_R1.3970.98
393_M405_E1.3970.98
147_H151_T1.3920.98
61_L71_I1.3910.98
81_E106_T1.3830.98
86_T89_D1.3740.98
343_H346_Y1.3730.98
81_E148_N1.3680.98
156_P159_K1.3670.98
246_Y250_R1.3540.98
221_V268_V1.3390.98
286_H313_T1.3250.98
678_A716_V1.3230.98
82_D107_K1.3200.98
682_T719_R1.3190.98
219_D223_N1.3110.98
33_L37_D1.3070.98
34_Y38_A1.3060.98
479_Q483_K1.3030.98
613_G641_I1.3000.98
230_E236_A1.2960.97
309_Q335_I1.2930.97
229_V281_V1.2870.97
205_N209_K1.2840.97
185_W242_P1.2820.97
430_A437_V1.2800.97
61_L105_V1.2770.97
679_V686_I1.2750.97
229_V236_A1.2720.97
612_V640_L1.2650.97
222_V238_F1.2620.97
140_I176_H1.2550.97
204_V245_I1.2530.97
211_R215_E1.2510.97
44_R148_N1.2510.97
518_Q522_D1.2460.97
631_V640_L1.2390.97
187_L191_A1.2310.97
412_P437_V1.2300.97
486_R490_V1.2300.97
665_G699_A1.2290.97
285_I315_V1.2230.96
437_V441_H1.2170.96
193_R204_V1.2160.96
285_I325_V1.2130.96
85_V89_D1.2040.96
462_Q481_F1.2020.96
600_S622_S1.2000.96
679_V705_I1.1850.96
32_Y36_E1.1830.96
710_I714_H1.1830.96
39_H78_D1.1800.96
53_H147_H1.1790.96
662_E702_H1.1770.96
149_M152_L1.1760.96
77_H167_T1.1740.95
39_H82_D1.1710.95
587_V611_I1.1650.95
691_G701_I1.1620.95
51_I54_P1.1620.95
36_E40_R1.1620.95
12_V17_R1.1610.95
192_L199_Q1.1610.95
668_R725_D1.1600.95
44_R82_D1.1570.95
272_V277_D1.1560.95
26_A29_E1.1530.95
38_A89_D1.1520.95
38_A85_V1.1500.95
614_F639_R1.1490.95
664_L728_S1.1480.95
675_V701_I1.1480.95
44_R78_D1.1440.95
624_H628_C1.1430.95
201_Y205_N1.1430.95
671_L699_A1.1430.95
226_K237_D1.1390.95
158_E162_R1.1380.95
82_D147_H1.1340.95
517_I529_E1.1340.95
679_V684_T1.1320.94
144_D148_N1.1300.94
241_R347_K1.1290.94
394_V445_T1.1280.94
200_Y204_V1.1250.94
54_P148_N1.1230.94
44_R50_Y1.1200.94
671_L674_E1.1190.94
678_A682_T1.1160.94
603_C628_C1.1150.94
39_H81_E1.1150.94
661_I703_M1.1140.94
78_D148_N1.1120.94
44_R147_H1.1080.94
363_S366_R1.1030.94
471_S475_H1.1020.94
16_A62_V1.0990.94
107_K148_N1.0960.93
85_V93_A1.0950.93
671_L723_I1.0910.93
394_V441_H1.0910.93
283_G286_H1.0890.93
656_E706_F1.0890.93
685_N706_F1.0860.93
480_F484_Q1.0840.93
412_P443_L1.0830.93
670_G685_N1.0750.93
17_R25_I1.0740.93
39_H50_Y1.0680.93
692_K702_H1.0670.93
282_L327_I1.0660.92
410_S469_Q1.0650.92
222_V268_V1.0640.92
44_R47_G1.0620.92
138_I174_L1.0620.92
411_V467_L1.0610.92
130_A394_V1.0610.92
82_D151_T1.0610.92
669_R683_K1.0570.92
606_V659_V1.0570.92
40_R43_Y1.0520.92
206_L260_N1.0520.92
228_R232_V1.0470.92
106_T148_N1.0470.92
155_L159_K1.0390.91
634_N637_Q1.0390.91
603_C624_H1.0390.91
56_Q59_G1.0390.91
279_Y283_G1.0390.91
661_I705_I1.0380.91
16_A19_Y1.0380.91
277_D281_V1.0360.91
37_D41_E1.0350.91
717_V721_K1.0340.91
343_H347_K1.0330.91
664_L700_T1.0320.91
341_A347_K1.0320.91
658_N704_A1.0290.91
426_K457_S1.0280.91
61_L66_M1.0280.91
610_D625_R1.0250.91
77_H148_N1.0240.91
395_Y405_E1.0230.91
104_G126_K1.0220.91
519_K522_D1.0200.91
207_M265_L1.0200.91
76_L98_V1.0180.91
96_E100_M1.0160.91
427_T439_L1.0130.90
131_M135_I1.0070.90
39_H148_N1.0050.90
291_P301_A1.0050.90
77_H81_E1.0030.90
217_Y221_V0.9980.90
50_Y78_D0.9980.90
54_P81_E0.9980.90
660_E702_H0.9980.90
236_A281_V0.9950.90
107_K144_D0.9940.90
78_D106_T0.9940.90
232_V284_I0.9930.90
78_D83_T0.9930.90
316_I320_G0.9910.89
674_E723_I0.9900.89
24_H68_P0.9870.89
50_Y82_D0.9810.89
249_Y253_V0.9810.89
38_A84_D0.9800.89
251_K346_Y0.9790.89
426_K456_H0.9780.89
54_P147_H0.9780.89
125_R318_P0.9770.89
331_E334_E0.9760.89
18_S410_S0.9760.89
662_E730_R0.9740.89
357_T360_K0.9710.88
42_Q81_E0.9700.88
252_M259_F0.9680.88
415_F419_I0.9670.88
81_E147_H0.9670.88
59_G63_D0.9660.88
658_N706_F0.9610.88
78_D167_T0.9600.88
39_H54_P0.9600.88
459_G480_F0.9600.88
398_T419_I0.9570.88
121_A473_A0.9560.88
267_A343_H0.9560.88
422_E425_N0.9540.88
60_I186_E0.9530.88
251_K343_H0.9520.87
50_Y148_N0.9520.87
279_Y286_H0.9520.87
309_Q630_N0.9510.87
324_E343_H0.9490.87
81_E151_T0.9490.87
50_Y147_H0.9480.87
585_A589_V0.9480.87
54_P82_D0.9470.87
61_L631_V0.9460.87
39_H44_R0.9450.87
54_P77_H0.9420.87
689_V693_S0.9410.87
682_T715_K0.9410.87
225_V325_V0.9390.87
73_G140_I0.9390.87
602_C624_H0.9390.87
616_T630_N0.9360.87
535_A541_I0.9340.86
425_N480_F0.9330.86
207_M259_F0.9320.86
279_Y282_L0.9290.86
149_M167_T0.9280.86
77_H147_H0.9270.86
334_E338_Y0.9270.86
57_V144_D0.9250.86
333_H337_E0.9250.86
161_R195_L0.9250.86
429_G452_L0.9240.86
251_K324_E0.9240.86
404_I418_R0.9220.86
44_R77_H0.9220.86
468_A473_A0.9220.86
359_E366_R0.9210.86
419_I422_E0.9190.86
20_L68_P0.9170.85
44_R81_E0.9160.85
251_K347_K0.9150.85
221_V289_W0.9150.85
44_R54_P0.9140.85
228_R284_I0.9110.85
709_N712_H0.9100.85
324_E346_Y0.9100.85
20_L23_E0.9090.85
673_N680_N0.9090.85
501_I547_A0.9080.85
127_M131_M0.9060.85
81_E144_D0.9060.85
53_H57_V0.9060.85
15_K59_G0.9040.85
241_R346_Y0.9030.85
599_L606_V0.9010.84
141_K148_N0.9000.84
11_Q59_G0.8980.84
383_E386_K0.8970.84
155_L162_R0.8960.84
688_S704_A0.8950.84
518_Q529_E0.8950.84
501_I533_Y0.8940.84
671_L725_D0.8930.84
69_S72_A0.8910.84
159_K162_R0.8910.84
209_K365_F0.8900.84
44_R151_T0.8900.84
90_L99_A0.8880.84
499_K502_K0.8860.83
54_P78_D0.8860.83
665_G726_I0.8850.83
723_I726_I0.8830.83
602_C628_C0.8820.83
589_V643_V0.8810.83
230_E235_K0.8780.83
341_A346_Y0.8750.83
193_R201_Y0.8730.83
532_M541_I0.8720.82
11_Q15_K0.8700.82
668_R723_I0.8690.82
667_D693_S0.8680.82
106_T151_T0.8660.82
74_G140_I0.8650.82
39_H106_T0.8650.82
42_Q82_D0.8590.81
146_L183_I0.8560.81
275_I287_T0.8550.81
39_H42_Q0.8540.81
83_T148_N0.8530.81
53_H148_N0.8510.81
160_Q431_K0.8500.81
53_H77_H0.8480.81
662_E700_T0.8480.81
324_E347_K0.8470.81
243_K343_H0.8450.80
14_D18_S0.8440.80
667_D697_K0.8440.80
524_F541_I0.8430.80
39_H77_H0.8420.80
77_H144_D0.8400.80
286_H296_F0.8400.80
161_R325_V0.8380.80
106_T147_H0.8350.80
46_S154_H0.8340.80
225_V427_T0.8310.79
77_H82_D0.8300.79
225_V268_V0.8300.79
39_H147_H0.8290.79
419_I477_I0.8280.79
345_A366_R0.8280.79
297_K314_T0.8270.79
243_K251_K0.8270.79
39_H151_T0.8220.79
224_E288_C0.8220.79
421_S480_F0.8210.78
709_N713_L0.8190.78
592_I595_L0.8190.78
677_Q681_E0.8160.78
224_E228_R0.8160.78
520_V546_V0.8150.78
140_I191_A0.8150.78
684_T716_V0.8140.78
358_F362_L0.8140.78
87_L90_L0.8120.78
39_H53_H0.8120.78
124_H289_W0.8090.77
213_E216_L0.8090.77
318_P672_L0.8060.77
129_V176_H0.8050.77
421_S476_K0.8040.77
77_H106_T0.8040.77
44_R107_K0.8040.77
282_L286_H0.8030.77
115_S118_E0.8020.77
50_Y53_H0.8020.77
693_S699_A0.8010.77
586_G589_V0.8000.77
50_Y54_P0.8000.77
462_Q485_R0.7990.77
247_S347_K0.7990.77
50_Y81_E0.7980.76
669_R685_N0.7980.76
12_V15_K0.7970.76
713_L717_V0.7970.76
431_K452_L0.7960.76
292_M322_P0.7960.76
54_P83_T0.7940.76
78_D147_H0.7930.76
44_R83_T0.7910.76
670_G676_L0.7900.76
42_Q83_T0.7890.76
28_V68_P0.7880.76
44_R53_H0.7860.75
123_N397_F0.7850.75
215_E242_P0.7840.75
397_F402_D0.7840.75
69_S98_V0.7840.75
621_V643_V0.7830.75
654_R663_I0.7830.75
665_G701_I0.7810.75
220_E223_N0.7800.75
531_D534_A0.7800.75
500_E503_N0.7790.75
269_R326_Q0.7790.75
657_Y707_I0.7790.75
50_Y77_H0.7780.75
483_K487_E0.7770.75
60_I143_A0.7770.75
269_R346_Y0.7760.74
53_H78_D0.7740.74
431_K436_M0.7740.74
616_T620_G0.7730.74
53_H144_D0.7730.74
16_A21_S0.7730.74
144_D147_H0.7710.74
170_I370_E0.7700.74
53_H151_T0.7700.74
251_K267_A0.7690.74
182_K623_V0.7690.74
269_R343_H0.7680.74
673_N677_Q0.7680.74
83_T151_T0.7660.73
159_K163_I0.7660.73
598_R619_R0.7660.73
53_H107_K0.7660.73
78_D107_K0.7650.73
430_A451_I0.7640.73
14_D17_R0.7630.73
504_L547_A0.7600.73
365_F371_F0.7590.73
43_Y49_P0.7590.73
129_V390_F0.7580.73
324_E341_A0.7580.73
50_Y151_T0.7570.73
207_M248_I0.7570.73
83_T106_T0.7560.73
210_K214_R0.7550.72
267_A346_Y0.7540.72
214_R242_P0.7540.72
251_K341_A0.7530.72
687_S706_F0.7530.72
50_Y83_T0.7520.72
62_V192_L0.7510.72
241_R343_H0.7510.72
252_M299_Y0.7500.72
413_I427_T0.7490.72
482_K538_Y0.7480.72
58_A74_G0.7460.72
44_R106_T0.7460.72
241_R267_A0.7440.71
44_R144_D0.7430.71
229_V238_F0.7430.71
203_I206_L0.7430.71
366_R369_L0.7410.71
588_R644_E0.7410.71
71_I74_G0.7400.71
678_A719_R0.7390.71
214_R301_A0.7390.71
144_D167_T0.7380.71
267_A347_K0.7380.71
217_Y319_K0.7380.71
83_T107_K0.7360.70
148_N159_K0.7350.70
107_K147_H0.7310.70
421_S666_Y0.7300.70
103_D126_K0.7300.70
475_H479_Q0.7290.70
12_V75_F0.7280.70
54_P57_V0.7270.70
104_G137_V0.7270.70
425_N481_F0.7260.69
77_H151_T0.7260.69
21_S24_H0.7250.69
198_Q201_Y0.7250.69
42_Q50_Y0.7240.69
107_K151_T0.7230.69
668_R675_V0.7220.69
148_N167_T0.7220.69
193_R211_R0.7210.69
54_P151_T0.7180.69
243_K324_E0.7160.68
307_M330_F0.7150.68
81_E107_K0.7140.68
46_S82_D0.7130.68
67_D70_T0.7130.68
20_L478_R0.7130.68
675_V679_V0.7130.68
367_E371_F0.7120.68
283_G287_T0.7100.68
236_A532_M0.7100.68
601_K604_N0.7090.68
153_K193_R0.7090.68
394_V471_S0.7090.68
30_K72_A0.7080.68
34_Y90_L0.7080.68
207_M319_K0.7070.67
467_L472_Q0.7070.67
47_G53_H0.7060.67
254_L259_F0.7060.67
390_F482_K0.7060.67
658_N687_S0.7060.67
109_G163_I0.7050.67
91_K95_S0.7040.67
126_K137_V0.7040.67
241_R324_E0.7030.67
470_T476_K0.7030.67
437_V720_I0.7030.67
145_R166_E0.7030.67
250_R254_L0.7020.67
105_V108_L0.7010.67
50_Y106_T0.7000.67
82_D159_K0.7000.67
105_V283_G0.7000.67
25_I29_E0.7000.67
120_Q139_L0.6990.67
661_I729_V0.6980.66
432_V449_V0.6980.66
230_E550_L0.6980.66
612_V626_E0.6980.66
53_H106_T0.6970.66
678_A723_I0.6970.66
83_T86_T0.6970.66
412_P441_H0.6970.66
81_E105_V0.6960.66
82_D144_D0.6960.66
417_Y460_P0.6950.66
491_E495_E0.6940.66
54_P107_K0.6930.66
199_Q249_Y0.6930.66
152_L160_Q0.6920.66
604_N660_E0.6920.66
307_M335_I0.6910.66
267_A325_V0.6900.66
394_V409_G0.6880.65
581_R623_V0.6850.65
220_E441_H0.6840.65
48_E53_H0.6840.65
672_L685_N0.6830.65
23_E26_A0.6810.65
81_E104_G0.6780.64
422_E426_K0.6780.64
107_K141_K0.6770.64
623_V641_I0.6770.64
91_K100_M0.6770.64
122_E607_P0.6760.64
60_I71_I0.6760.64
356_A359_E0.6760.64
149_M160_Q0.6750.64
257_K261_E0.6750.64
185_W188_E0.6720.63
53_H81_E0.6700.63
270_I717_V0.6700.63
64_L183_I0.6690.63
144_D151_T0.6690.63
78_D151_T0.6690.63
13_I25_I0.6680.63
412_P442_K0.6670.63
128_F132_A0.6670.63
20_L98_V0.6670.63
139_L180_I0.6670.63
497_V546_V0.6670.63
17_R23_E0.6660.63
264_D346_Y0.6660.63
625_R671_L0.6660.63
241_R341_A0.6650.63
436_M452_L0.6640.63
83_T147_H0.6630.62
203_I259_F0.6630.62
264_D343_H0.6630.62
73_G102_V0.6620.62
326_Q346_Y0.6620.62
125_R460_P0.6620.62
378_A721_K0.6610.62
497_V532_M0.6610.62
229_V234_I0.6600.62
41_E49_P0.6600.62
251_K269_R0.6600.62
535_A540_G0.6590.62
135_I139_L0.6580.62
527_S531_D0.6580.62
586_G591_G0.6570.62
234_I281_V0.6560.62
269_R324_E0.6560.62
596_L621_V0.6550.61
189_D193_R0.6550.61
44_R159_K0.6540.61
53_H82_D0.6530.61
521_A533_Y0.6520.61
481_F622_S0.6520.61
21_S25_I0.6520.61
317_G369_L0.6520.61
24_H27_F0.6510.61
243_K346_Y0.6500.61
80_V89_D0.6490.61
322_P481_F0.6490.61
172_A244_H0.6490.61
78_D102_V0.6470.61
120_Q127_M0.6470.61
20_L24_H0.6470.61
676_L725_D0.6450.60
39_H83_T0.6450.60
183_I661_I0.6450.60
264_D324_E0.6450.60
668_R699_A0.6450.60
57_V77_H0.6440.60
164_S195_L0.6440.60
92_E96_E0.6430.60
214_R240_G0.6420.60
53_H79_V0.6420.60
16_A25_I0.6420.60
155_L160_Q0.6420.60
54_P106_T0.6400.60
220_E224_E0.6390.60
496_L536_V0.6380.59
493_G537_G0.6380.59
39_H47_G0.6350.59
124_H206_L0.6350.59
556_K559_D0.6350.59
213_E265_L0.6340.59
675_V678_A0.6340.59
131_M309_Q0.6330.59
172_A187_L0.6320.59
307_M334_E0.6320.59
141_K145_R0.6320.59
514_P518_Q0.6310.59
233_N470_T0.6310.59
42_Q78_D0.6300.59
708_Q712_H0.6300.59
676_L701_I0.6300.59
254_L257_K0.6290.58
102_V145_R0.6270.58
251_K326_Q0.6250.58
689_V701_I0.6240.58
228_R287_T0.6240.58
86_T705_I0.6230.58
672_L691_G0.6230.58
326_Q343_H0.6210.57
486_R530_E0.6200.57
251_K264_D0.6180.57
408_S442_K0.6170.57
46_S50_Y0.6160.57
205_N208_K0.6160.57
500_E504_L0.6160.57
194_Y433_N0.6150.57
66_M180_I0.6150.57
280_A284_I0.6140.57
381_F386_K0.6120.56
81_E159_K0.6120.56
169_E386_K0.6110.56
349_G352_A0.6110.56
105_V141_K0.6110.56
70_T101_L0.6090.56
290_K397_F0.6080.56
216_L219_D0.6070.56
413_I537_G0.6060.56
42_Q148_N0.6060.56
241_R251_K0.6050.55
243_K347_K0.6040.55
656_E708_Q0.6040.55
606_V731_R0.6030.55
412_P439_L0.6020.55
689_V699_A0.6020.55
39_H46_S0.6010.55
318_P323_L0.6010.55
676_L680_N0.6010.55
105_V109_G0.6010.55
57_V74_G0.6010.55
78_D159_K0.6000.55
76_L90_L0.6000.55
714_H718_E0.5990.55
344_W602_C0.5980.55
445_T712_H0.5980.55
128_F472_Q0.5960.54
12_V59_G0.5960.54
127_M371_F0.5960.54
244_H463_D0.5960.54
605_P624_H0.5950.54
279_Y301_A0.5940.54
46_S107_K0.5930.54
47_G106_T0.5930.54
132_A291_P0.5930.54
590_K644_E0.5930.54
637_Q640_L0.5910.54
667_D670_G0.5910.54
438_T442_K0.5910.54
426_K454_S0.5900.54
345_A359_E0.5890.54
310_S328_R0.5890.54
264_D326_Q0.5890.54
678_A705_I0.5890.54
613_G643_V0.5880.53
333_H338_Y0.5870.53
659_V685_N0.5870.53
57_V107_K0.5860.53
44_R141_K0.5850.53
63_D623_V0.5850.53
395_Y591_G0.5850.53
387_I395_Y0.5840.53
519_K553_K0.5840.53
369_L389_L0.5840.53
80_V86_T0.5830.53
22_D26_A0.5810.53
152_L155_L0.5800.52
106_T144_D0.5800.52
415_F451_I0.5790.52
590_K646_E0.5790.52
49_P53_H0.5790.52
78_D144_D0.5790.52
262_I659_V0.5780.52
323_L402_D0.5770.52
60_I74_G0.5770.52
371_F374_E0.5760.52
241_R247_S0.5760.52
47_G148_N0.5750.52
46_S53_H0.5750.52
192_L255_Q0.5740.52
46_S57_V0.5740.52
27_F97_E0.5740.52
39_H159_K0.5730.52
249_Y468_A0.5730.52
135_I294_G0.5730.52
589_V641_I0.5730.52
151_T159_K0.5730.52
267_A449_V0.5720.51
28_V40_R0.5720.51
502_K589_V0.5720.51
149_M164_S0.5710.51
506_F551_T0.5710.51
402_D422_E0.5700.51
218_V438_T0.5700.51
77_H107_K0.5690.51
13_I16_A0.5690.51
270_I275_I0.5690.51
525_N540_G0.5690.51
235_K726_I0.5690.51
623_V684_T0.5690.51
679_V716_V0.5690.51
161_R165_N0.5690.51
292_M296_F0.5690.51
342_A346_Y0.5680.51
140_I643_V0.5680.51
50_Y57_V0.5670.51
120_Q369_L0.5670.51
165_N195_L0.5660.51
267_A324_E0.5660.51
536_V542_T0.5660.51
145_R163_I0.5650.51
498_E533_Y0.5650.51
129_V341_A0.5650.51
555_R661_I0.5650.51
32_Y55_I0.5640.50
110_K413_I0.5640.50
411_V676_L0.5630.50
312_H328_R0.5620.50
432_V436_M0.5620.50
44_R48_E0.5620.50
120_Q123_N0.5620.50
247_S341_A0.5600.50
498_E508_L0.5600.50
222_V239_S0.5590.50
317_G321_D0.5590.50
65_E345_A0.5590.50
427_T676_L0.5590.50
135_I306_N0.5590.50
209_K266_L0.5590.50
124_H363_S0.5590.50
392_D657_Y0.5590.50
673_N676_L0.5580.50
419_I597_V0.5580.50
149_M199_Q0.5570.50
35_A466_K0.5560.49
412_P436_M0.5550.49
247_S324_E0.5550.49
15_K18_S0.5550.49
667_D671_L0.5550.49
189_D194_Y0.5540.49
552_E555_R0.5530.49
246_Y249_Y0.5530.49
52_I56_Q0.5530.49
390_F445_T0.5530.49
531_D679_V0.5530.49
286_H299_Y0.5520.49
279_Y313_T0.5510.49
14_D24_H0.5510.49
184_K188_E0.5510.49
243_K326_Q0.5510.49
218_V238_F0.5510.49
100_M268_V0.5500.49
516_N554_E0.5500.49
196_N349_G0.5490.49
534_A538_Y0.5490.49
107_K145_R0.5490.49
282_L299_Y0.5490.49
217_Y321_D0.5490.49
523_K552_E0.5490.49
104_G130_A0.5480.48
484_Q487_E0.5480.48
82_D141_K0.5470.48
491_E494_R0.5470.48
292_M314_T0.5470.48
247_S251_K0.5470.48
184_K248_I0.5470.48
283_G296_F0.5460.48
171_F419_I0.5460.48
461_S466_K0.5450.48
147_H159_K0.5450.48
680_N686_I0.5450.48
421_S429_G0.5450.48
430_A476_K0.5440.48
605_P628_C0.5440.48
39_H102_V0.5440.48
363_S367_E0.5430.48
164_S451_I0.5420.48
259_F457_S0.5420.48
181_S597_V0.5420.48
616_T639_R0.5420.48
57_V78_D0.5420.48
121_A389_L0.5420.48
34_Y40_R0.5410.48
243_K341_A0.5400.47
141_K144_D0.5400.47
46_S81_E0.5400.47
476_K479_Q0.5400.47
54_P144_D0.5390.47
285_I288_C0.5390.47
490_V659_V0.5390.47
103_D472_Q0.5380.47
411_V465_V0.5380.47
410_S727_Y0.5370.47
98_V507_E0.5370.47
191_A409_G0.5370.47
106_T167_T0.5360.47
475_H612_V0.5360.47
438_T441_H0.5350.47
113_Y270_I0.5350.47
300_I620_G0.5350.47
184_K267_A0.5350.47
126_K291_P0.5350.47
329_T467_L0.5340.47
192_L286_H0.5340.47
494_R530_E0.5330.47
242_P323_L0.5320.46
81_E141_K0.5320.46
426_K453_T0.5310.46
632_K661_I0.5310.46
672_L703_M0.5310.46
638_E675_V0.5300.46
99_A103_D0.5300.46
67_D333_H0.5300.46
302_M307_M0.5290.46
165_N196_N0.5290.46
387_I393_M0.5290.46
211_R245_I0.5280.46
83_T144_D0.5280.46
293_P447_D0.5280.46
149_M159_K0.5270.46
524_F532_M0.5270.46
321_D427_T0.5270.46
451_I582_K0.5270.46
244_H333_H0.5260.46
428_I454_S0.5260.46
377_D380_E0.5260.46
609_D692_K0.5250.46
270_I557_Q0.5250.46
32_Y483_K0.5250.46
116_Q162_R0.5250.46
62_V283_G0.5240.45
663_I726_I0.5240.45
266_L321_D0.5240.45
165_N623_V0.5240.45
13_I29_E0.5230.45
279_Y299_Y0.5230.45
311_L369_L0.5220.45
536_V546_V0.5220.45
28_V75_F0.5220.45
203_I365_F0.5220.45
149_M155_L0.5220.45
264_D269_R0.5220.45
366_R500_E0.5220.45
418_R531_D0.5210.45
101_L108_L0.5210.45
191_A194_Y0.5210.45
244_H619_R0.5200.45
12_V32_Y0.5200.45
39_H144_D0.5200.45
586_G646_E0.5200.45
666_Y727_Y0.5190.45
65_E128_F0.5180.45
187_L396_V0.5180.45
353_N716_V0.5170.45
262_I630_N0.5160.44
243_K267_A0.5160.44
77_H102_V0.5150.44
21_S26_A0.5140.44
193_R285_I0.5140.44
24_H30_K0.5140.44
325_V621_V0.5140.44
20_L71_I0.5140.44
53_H94_F0.5130.44
609_D625_R0.5130.44
426_K470_T0.5120.44
33_L40_R0.5120.44
92_E577_Y0.5120.44
306_N313_T0.5120.44
156_P648_E0.5120.44
340_V373_N0.5110.44
47_G144_D0.5110.44
662_E732_V0.5110.44
709_N722_Q0.5110.44
105_V373_N0.5110.44
78_D152_L0.5100.44
48_E147_H0.5100.44
461_S481_F0.5100.44
168_L191_A0.5100.44
247_S326_Q0.5100.44
39_H167_T0.5100.44
180_I348_E0.5090.44
269_R347_K0.5090.44
217_Y266_L0.5080.43
82_D102_V0.5080.43
76_L80_V0.5080.43
629_P661_I0.5080.43
501_I550_L0.5060.43
17_R29_E0.5060.43
167_T187_L0.5060.43
374_E377_D0.5060.43
296_F402_D0.5060.43
191_A468_A0.5060.43
244_H348_E0.5050.43
132_A189_D0.5040.43
449_V686_I0.5040.43
145_R171_F0.5040.43
495_E499_K0.5030.43
289_W485_R0.5020.43
34_Y37_D0.5020.43
221_V266_L0.5020.43
284_I508_L0.5010.43
516_N519_K0.5010.43
526_F541_I0.5000.43
689_V720_I0.5000.43
78_D163_I0.5000.43
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1vj7A 1 0.4564 100 0.517 Contact Map
3l9dA 1 0.2534 100 0.771 Contact Map
4yf1A 2 0.2098 100 0.826 Contact Map
3nr1A 2 0.2371 100 0.834 Contact Map
2be3A 2 0.2616 100 0.838 Contact Map
3nqwA 2 0.233 100 0.84 Contact Map
2ekiA 1 0.1144 99.9 0.924 Contact Map
3hvzA 2 0.0872 99.7 0.937 Contact Map
1wxqA 1 0.2902 99.5 0.947 Contact Map
3j7y7 1 0.3351 99.4 0.948 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0176 seconds.