RELA - BACSU - GREMLIN Contacts

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RELA - GTP pyrophosphokinase

UniProt:	O54408	Sequences: MANEQVLTAEQVIDKARSYLSDEHIAFVEKAYLYAEDAHREQYRKSGEPYIIHPIQVAGILVDLEMDPSTIAGGFLHDVVEDTDVTLDDLKEAFSEEVAMLVDGVTKLGKIKYKSQEEQQAENHRKMFVAMAQDIRVILIKLADRLHNMRTLKHLPQEKQRRISNETLEIFAPLAHRLGISKIKWELEDTALRYLNPQQYYRIVNLMKKKRAERELYVDEVVNEVKKRVEEVNIKADFSGRPKHIYSIYRKMVLQNKQFNEIYDLLAVRILVNSIKDCYAVLGIIHTCWKPMPGRFKDYIAMPKPNMYQSLHTTVIGPKGDPLEVQIRTFEMHEIAEYGVAAHWAYKEGKAANEGATFEKKLSWFREILEFQNESTDAEEFMESLKIDLFSDMVYVFTPKGDVIELPSGSVPIDFSYRIHSEIGNKTIGAKVNGKMVTLDHKLRTGDIVEILTSKHSYGPSQDWVKLAQTSQAKHKIRQFFKKQRREENVEKGRELVEKEIKNLDFELKDVLTPENIQKVADKFNFSNEEDMYAAVGYNGITALQVANRLTEKERKQRDQEEQEKIVQEVTGEPKPYPQGRKREAGVRVKGIDNLLVRLSKCCNPVPGDDIVGFITKGRGVSVHREDCPNVKTNEAQERLIPVEWEHESQVQKRKEYNVEIEILGYDRRGLLNEVLQAVNETKTNISSVSGKSDRNKVATIHMAIFIQNINHLHKVVERIKQIRDIYSVRRVMN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	734 (702)
Sequences:	3426 (1942)
Seq/√Len:	73.3

ECOLI - RELA SPOT
BACSU - RELA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
91_K	96_E	7.238	1.00
497_V	536_V	5.400	1.00
417_Y	425_N	5.316	1.00
433_N	447_D	4.938	1.00
432_V	437_V	4.776	1.00
717_V	729_V	4.627	1.00
413_I	467_L	4.444	1.00
66_M	139_L	4.330	1.00
235_K	273_N	4.293	1.00
30_K	93_A	4.250	1.00
80_V	87_L	4.196	1.00
274_S	277_D	3.824	1.00
468_A	477_I	3.764	1.00
150_R	186_E	3.762	1.00
273_N	330_F	3.696	1.00
27_F	72_A	3.654	1.00
271_L	330_F	3.603	1.00
237_D	330_F	3.593	1.00
228_R	231_E	3.449	1.00
28_V	71_I	3.406	1.00
69_S	97_E	3.294	1.00
668_R	674_E	3.290	1.00
225_V	285_I	3.234	1.00
157_Q	160_Q	3.159	1.00
165_N	169_E	2.956	1.00
432_V	441_H	2.942	1.00
423_I	453_T	2.913	1.00
526_F	535_A	2.894	1.00
257_K	262_I	2.889	1.00
152_L	194_Y	2.883	1.00
239_S	333_H	2.881	1.00
220_E	319_K	2.711	1.00
203_I	245_I	2.683	1.00
490_V	534_A	2.677	1.00
202_R	206_L	2.667	1.00
16_A	28_V	2.652	1.00
37_D	40_R	2.647	1.00
442_K	469_Q	2.607	1.00
196_N	199_Q	2.600	1.00
663_I	720_I	2.574	1.00
34_Y	85_V	2.558	1.00
610_D	626_E	2.548	1.00
206_L	259_F	2.541	1.00
623_V	643_V	2.448	1.00
494_R	533_Y	2.420	1.00
689_V	703_M	2.407	1.00
87_L	103_D	2.402	1.00
61_L	70_T	2.377	1.00
80_V	90_L	2.368	1.00
29_E	33_L	2.364	1.00
443_L	449_V	2.338	1.00
661_I	717_V	2.328	1.00
226_K	230_E	2.305	1.00
470_T	473_A	2.279	1.00
660_E	704_A	2.268	1.00
398_T	404_I	2.265	1.00
89_D	92_E	2.262	1.00
101_L	140_I	2.251	1.00
157_Q	161_R	2.247	1.00
281_V	284_I	2.194	1.00
665_G	671_L	2.187	1.00
58_A	71_I	2.152	1.00
490_V	530_E	2.147	1.00
273_N	277_D	2.146	1.00
431_K	450_E	2.111	1.00
210_K	213_E	2.108	1.00
217_Y	317_G	2.107	1.00
100_M	133_Q	2.106	1.00
521_A	529_E	2.095	1.00
155_L	163_I	2.053	1.00
616_T	622_S	2.046	1.00
705_I	716_V	2.018	1.00
270_I	281_V	2.006	1.00
410_S	470_T	2.005	1.00
27_F	30_K	2.001	1.00
227_K	231_E	1.992	1.00
66_M	70_T	1.972	1.00
528_N	531_D	1.967	1.00
612_V	631_V	1.958	1.00
216_L	220_E	1.954	1.00
276_K	280_A	1.932	1.00
684_T	712_H	1.920	1.00
160_Q	194_Y	1.920	1.00
330_F	334_E	1.875	1.00
272_V	281_V	1.873	1.00
68_P	72_A	1.861	1.00
45_K	155_L	1.860	1.00
149_M	187_L	1.841	1.00
221_V	323_L	1.838	1.00
222_V	226_K	1.835	1.00
223_N	227_K	1.823	1.00
152_L	163_I	1.810	1.00
87_L	91_K	1.807	1.00
412_P	430_A	1.804	1.00
217_Y	318_P	1.795	1.00
164_S	191_A	1.794	1.00
277_D	280_A	1.785	1.00
61_L	74_G	1.782	1.00
199_Q	202_R	1.775	1.00
441_H	444_R	1.766	1.00
33_L	36_E	1.761	1.00
78_D	82_D	1.758	1.00
218_V	240_G	1.743	1.00
396_V	443_L	1.728	1.00
526_F	532_M	1.726	1.00
211_R	242_P	1.722	1.00
27_F	69_S	1.708	1.00
663_I	703_M	1.707	1.00
19_Y	65_E	1.706	1.00
207_M	245_I	1.700	1.00
441_H	447_D	1.696	1.00
88_D	91_K	1.694	1.00
15_K	63_D	1.694	1.00
421_S	425_N	1.687	1.00
185_W	244_H	1.681	1.00
27_F	98_V	1.674	1.00
87_L	99_A	1.666	1.00
72_A	98_V	1.657	1.00
529_E	533_Y	1.654	1.00
409_G	442_K	1.638	1.00
223_N	226_K	1.636	1.00
152_L	164_S	1.631	1.00
485_R	488_E	1.630	1.00
88_D	92_E	1.629	1.00
215_E	219_D	1.622	0.99
201_Y	204_V	1.609	0.99
228_R	288_C	1.608	0.99
454_S	457_S	1.600	0.99
209_K	321_D	1.593	0.99
35_A	51_I	1.593	0.99
73_G	101_L	1.590	0.99
185_W	211_R	1.588	0.99
412_P	432_V	1.556	0.99
497_V	533_Y	1.551	0.99
91_K	99_A	1.550	0.99
679_V	703_M	1.547	0.99
590_K	642_P	1.539	0.99
667_D	699_A	1.538	0.99
80_V	103_D	1.538	0.99
82_D	106_T	1.538	0.99
26_A	30_K	1.535	0.99
192_L	245_I	1.528	0.99
87_L	100_M	1.527	0.99
486_R	531_D	1.521	0.99
534_A	537_G	1.520	0.99
413_I	468_A	1.519	0.99
668_R	671_L	1.509	0.99
80_V	106_T	1.490	0.99
192_L	196_N	1.490	0.99
672_L	689_V	1.488	0.99
295_R	314_T	1.480	0.99
371_F	375_S	1.461	0.99
78_D	81_E	1.457	0.99
82_D	148_N	1.456	0.99
219_D	222_V	1.451	0.99
80_V	99_A	1.450	0.99
224_E	289_W	1.450	0.99
168_L	246_Y	1.441	0.99
34_Y	93_A	1.436	0.99
719_R	722_Q	1.423	0.99
148_N	151_T	1.422	0.99
16_A	20_L	1.419	0.99
149_M	190_T	1.418	0.99
89_D	93_A	1.415	0.99
418_R	472_Q	1.399	0.98
60_I	150_R	1.397	0.98
393_M	405_E	1.397	0.98
147_H	151_T	1.392	0.98
61_L	71_I	1.391	0.98
81_E	106_T	1.383	0.98
86_T	89_D	1.374	0.98
343_H	346_Y	1.373	0.98
81_E	148_N	1.368	0.98
156_P	159_K	1.367	0.98
246_Y	250_R	1.354	0.98
221_V	268_V	1.339	0.98
286_H	313_T	1.325	0.98
678_A	716_V	1.323	0.98
82_D	107_K	1.320	0.98
682_T	719_R	1.319	0.98
219_D	223_N	1.311	0.98
33_L	37_D	1.307	0.98
34_Y	38_A	1.306	0.98
479_Q	483_K	1.303	0.98
613_G	641_I	1.300	0.98
230_E	236_A	1.296	0.97
309_Q	335_I	1.293	0.97
229_V	281_V	1.287	0.97
205_N	209_K	1.284	0.97
185_W	242_P	1.282	0.97
430_A	437_V	1.280	0.97
61_L	105_V	1.277	0.97
679_V	686_I	1.275	0.97
229_V	236_A	1.272	0.97
612_V	640_L	1.265	0.97
222_V	238_F	1.262	0.97
140_I	176_H	1.255	0.97
204_V	245_I	1.253	0.97
211_R	215_E	1.251	0.97
44_R	148_N	1.251	0.97
518_Q	522_D	1.246	0.97
631_V	640_L	1.239	0.97
187_L	191_A	1.231	0.97
412_P	437_V	1.230	0.97
486_R	490_V	1.230	0.97
665_G	699_A	1.229	0.97
285_I	315_V	1.223	0.96
437_V	441_H	1.217	0.96
193_R	204_V	1.216	0.96
285_I	325_V	1.213	0.96
85_V	89_D	1.204	0.96
462_Q	481_F	1.202	0.96
600_S	622_S	1.200	0.96
679_V	705_I	1.185	0.96
32_Y	36_E	1.183	0.96
710_I	714_H	1.183	0.96
39_H	78_D	1.180	0.96
53_H	147_H	1.179	0.96
662_E	702_H	1.177	0.96
149_M	152_L	1.176	0.96
77_H	167_T	1.174	0.95
39_H	82_D	1.171	0.95
587_V	611_I	1.165	0.95
691_G	701_I	1.162	0.95
51_I	54_P	1.162	0.95
36_E	40_R	1.162	0.95
12_V	17_R	1.161	0.95
192_L	199_Q	1.161	0.95
668_R	725_D	1.160	0.95
44_R	82_D	1.157	0.95
272_V	277_D	1.156	0.95
26_A	29_E	1.153	0.95
38_A	89_D	1.152	0.95
38_A	85_V	1.150	0.95
614_F	639_R	1.149	0.95
664_L	728_S	1.148	0.95
675_V	701_I	1.148	0.95
44_R	78_D	1.144	0.95
624_H	628_C	1.143	0.95
201_Y	205_N	1.143	0.95
671_L	699_A	1.143	0.95
226_K	237_D	1.139	0.95
158_E	162_R	1.138	0.95
82_D	147_H	1.134	0.95
517_I	529_E	1.134	0.95
679_V	684_T	1.132	0.94
144_D	148_N	1.130	0.94
241_R	347_K	1.129	0.94
394_V	445_T	1.128	0.94
200_Y	204_V	1.125	0.94
54_P	148_N	1.123	0.94
44_R	50_Y	1.120	0.94
671_L	674_E	1.119	0.94
678_A	682_T	1.116	0.94
603_C	628_C	1.115	0.94
39_H	81_E	1.115	0.94
661_I	703_M	1.114	0.94
78_D	148_N	1.112	0.94
44_R	147_H	1.108	0.94
363_S	366_R	1.103	0.94
471_S	475_H	1.102	0.94
16_A	62_V	1.099	0.94
107_K	148_N	1.096	0.93
85_V	93_A	1.095	0.93
671_L	723_I	1.091	0.93
394_V	441_H	1.091	0.93
283_G	286_H	1.089	0.93
656_E	706_F	1.089	0.93
685_N	706_F	1.086	0.93
480_F	484_Q	1.084	0.93
412_P	443_L	1.083	0.93
670_G	685_N	1.075	0.93
17_R	25_I	1.074	0.93
39_H	50_Y	1.068	0.93
692_K	702_H	1.067	0.93
282_L	327_I	1.066	0.92
410_S	469_Q	1.065	0.92
222_V	268_V	1.064	0.92
44_R	47_G	1.062	0.92
138_I	174_L	1.062	0.92
411_V	467_L	1.061	0.92
130_A	394_V	1.061	0.92
82_D	151_T	1.061	0.92
669_R	683_K	1.057	0.92
606_V	659_V	1.057	0.92
40_R	43_Y	1.052	0.92
206_L	260_N	1.052	0.92
228_R	232_V	1.047	0.92
106_T	148_N	1.047	0.92
155_L	159_K	1.039	0.91
634_N	637_Q	1.039	0.91
603_C	624_H	1.039	0.91
56_Q	59_G	1.039	0.91
279_Y	283_G	1.039	0.91
661_I	705_I	1.038	0.91
16_A	19_Y	1.038	0.91
277_D	281_V	1.036	0.91
37_D	41_E	1.035	0.91
717_V	721_K	1.034	0.91
343_H	347_K	1.033	0.91
664_L	700_T	1.032	0.91
341_A	347_K	1.032	0.91
658_N	704_A	1.029	0.91
426_K	457_S	1.028	0.91
61_L	66_M	1.028	0.91
610_D	625_R	1.025	0.91
77_H	148_N	1.024	0.91
395_Y	405_E	1.023	0.91
104_G	126_K	1.022	0.91
519_K	522_D	1.020	0.91
207_M	265_L	1.020	0.91
76_L	98_V	1.018	0.91
96_E	100_M	1.016	0.91
427_T	439_L	1.013	0.90
131_M	135_I	1.007	0.90
39_H	148_N	1.005	0.90
291_P	301_A	1.005	0.90
77_H	81_E	1.003	0.90
217_Y	221_V	0.998	0.90
50_Y	78_D	0.998	0.90
54_P	81_E	0.998	0.90
660_E	702_H	0.998	0.90
236_A	281_V	0.995	0.90
107_K	144_D	0.994	0.90
78_D	106_T	0.994	0.90
232_V	284_I	0.993	0.90
78_D	83_T	0.993	0.90
316_I	320_G	0.991	0.89
674_E	723_I	0.990	0.89
24_H	68_P	0.987	0.89
50_Y	82_D	0.981	0.89
249_Y	253_V	0.981	0.89
38_A	84_D	0.980	0.89
251_K	346_Y	0.979	0.89
426_K	456_H	0.978	0.89
54_P	147_H	0.978	0.89
125_R	318_P	0.977	0.89
331_E	334_E	0.976	0.89
18_S	410_S	0.976	0.89
662_E	730_R	0.974	0.89
357_T	360_K	0.971	0.88
42_Q	81_E	0.970	0.88
252_M	259_F	0.968	0.88
415_F	419_I	0.967	0.88
81_E	147_H	0.967	0.88
59_G	63_D	0.966	0.88
658_N	706_F	0.961	0.88
78_D	167_T	0.960	0.88
39_H	54_P	0.960	0.88
459_G	480_F	0.960	0.88
398_T	419_I	0.957	0.88
121_A	473_A	0.956	0.88
267_A	343_H	0.956	0.88
422_E	425_N	0.954	0.88
60_I	186_E	0.953	0.88
251_K	343_H	0.952	0.87
50_Y	148_N	0.952	0.87
279_Y	286_H	0.952	0.87
309_Q	630_N	0.951	0.87
324_E	343_H	0.949	0.87
81_E	151_T	0.949	0.87
50_Y	147_H	0.948	0.87
585_A	589_V	0.948	0.87
54_P	82_D	0.947	0.87
61_L	631_V	0.946	0.87
39_H	44_R	0.945	0.87
54_P	77_H	0.942	0.87
689_V	693_S	0.941	0.87
682_T	715_K	0.941	0.87
225_V	325_V	0.939	0.87
73_G	140_I	0.939	0.87
602_C	624_H	0.939	0.87
616_T	630_N	0.936	0.87
535_A	541_I	0.934	0.86
425_N	480_F	0.933	0.86
207_M	259_F	0.932	0.86
279_Y	282_L	0.929	0.86
149_M	167_T	0.928	0.86
77_H	147_H	0.927	0.86
334_E	338_Y	0.927	0.86
57_V	144_D	0.925	0.86
333_H	337_E	0.925	0.86
161_R	195_L	0.925	0.86
429_G	452_L	0.924	0.86
251_K	324_E	0.924	0.86
404_I	418_R	0.922	0.86
44_R	77_H	0.922	0.86
468_A	473_A	0.922	0.86
359_E	366_R	0.921	0.86
419_I	422_E	0.919	0.86
20_L	68_P	0.917	0.85
44_R	81_E	0.916	0.85
251_K	347_K	0.915	0.85
221_V	289_W	0.915	0.85
44_R	54_P	0.914	0.85
228_R	284_I	0.911	0.85
709_N	712_H	0.910	0.85
324_E	346_Y	0.910	0.85
20_L	23_E	0.909	0.85
673_N	680_N	0.909	0.85
501_I	547_A	0.908	0.85
127_M	131_M	0.906	0.85
81_E	144_D	0.906	0.85
53_H	57_V	0.906	0.85
15_K	59_G	0.904	0.85
241_R	346_Y	0.903	0.85
599_L	606_V	0.901	0.84
141_K	148_N	0.900	0.84
11_Q	59_G	0.898	0.84
383_E	386_K	0.897	0.84
155_L	162_R	0.896	0.84
688_S	704_A	0.895	0.84
518_Q	529_E	0.895	0.84
501_I	533_Y	0.894	0.84
671_L	725_D	0.893	0.84
69_S	72_A	0.891	0.84
159_K	162_R	0.891	0.84
209_K	365_F	0.890	0.84
44_R	151_T	0.890	0.84
90_L	99_A	0.888	0.84
499_K	502_K	0.886	0.83
54_P	78_D	0.886	0.83
665_G	726_I	0.885	0.83
723_I	726_I	0.883	0.83
602_C	628_C	0.882	0.83
589_V	643_V	0.881	0.83
230_E	235_K	0.878	0.83
341_A	346_Y	0.875	0.83
193_R	201_Y	0.873	0.83
532_M	541_I	0.872	0.82
11_Q	15_K	0.870	0.82
668_R	723_I	0.869	0.82
667_D	693_S	0.868	0.82
106_T	151_T	0.866	0.82
74_G	140_I	0.865	0.82
39_H	106_T	0.865	0.82
42_Q	82_D	0.859	0.81
146_L	183_I	0.856	0.81
275_I	287_T	0.855	0.81
39_H	42_Q	0.854	0.81
83_T	148_N	0.853	0.81
53_H	148_N	0.851	0.81
160_Q	431_K	0.850	0.81
53_H	77_H	0.848	0.81
662_E	700_T	0.848	0.81
324_E	347_K	0.847	0.81
243_K	343_H	0.845	0.80
14_D	18_S	0.844	0.80
667_D	697_K	0.844	0.80
524_F	541_I	0.843	0.80
39_H	77_H	0.842	0.80
77_H	144_D	0.840	0.80
286_H	296_F	0.840	0.80
161_R	325_V	0.838	0.80
106_T	147_H	0.835	0.80
46_S	154_H	0.834	0.80
225_V	427_T	0.831	0.79
77_H	82_D	0.830	0.79
225_V	268_V	0.830	0.79
39_H	147_H	0.829	0.79
419_I	477_I	0.828	0.79
345_A	366_R	0.828	0.79
297_K	314_T	0.827	0.79
243_K	251_K	0.827	0.79
39_H	151_T	0.822	0.79
224_E	288_C	0.822	0.79
421_S	480_F	0.821	0.78
709_N	713_L	0.819	0.78
592_I	595_L	0.819	0.78
677_Q	681_E	0.816	0.78
224_E	228_R	0.816	0.78
520_V	546_V	0.815	0.78
140_I	191_A	0.815	0.78
684_T	716_V	0.814	0.78
358_F	362_L	0.814	0.78
87_L	90_L	0.812	0.78
39_H	53_H	0.812	0.78
124_H	289_W	0.809	0.77
213_E	216_L	0.809	0.77
318_P	672_L	0.806	0.77
129_V	176_H	0.805	0.77
421_S	476_K	0.804	0.77
77_H	106_T	0.804	0.77
44_R	107_K	0.804	0.77
282_L	286_H	0.803	0.77
115_S	118_E	0.802	0.77
50_Y	53_H	0.802	0.77
693_S	699_A	0.801	0.77
586_G	589_V	0.800	0.77
50_Y	54_P	0.800	0.77
462_Q	485_R	0.799	0.77
247_S	347_K	0.799	0.77
50_Y	81_E	0.798	0.76
669_R	685_N	0.798	0.76
12_V	15_K	0.797	0.76
713_L	717_V	0.797	0.76
431_K	452_L	0.796	0.76
292_M	322_P	0.796	0.76
54_P	83_T	0.794	0.76
78_D	147_H	0.793	0.76
44_R	83_T	0.791	0.76
670_G	676_L	0.790	0.76
42_Q	83_T	0.789	0.76
28_V	68_P	0.788	0.76
44_R	53_H	0.786	0.75
123_N	397_F	0.785	0.75
215_E	242_P	0.784	0.75
397_F	402_D	0.784	0.75
69_S	98_V	0.784	0.75
621_V	643_V	0.783	0.75
654_R	663_I	0.783	0.75
665_G	701_I	0.781	0.75
220_E	223_N	0.780	0.75
531_D	534_A	0.780	0.75
500_E	503_N	0.779	0.75
269_R	326_Q	0.779	0.75
657_Y	707_I	0.779	0.75
50_Y	77_H	0.778	0.75
483_K	487_E	0.777	0.75
60_I	143_A	0.777	0.75
269_R	346_Y	0.776	0.74
53_H	78_D	0.774	0.74
431_K	436_M	0.774	0.74
616_T	620_G	0.773	0.74
53_H	144_D	0.773	0.74
16_A	21_S	0.773	0.74
144_D	147_H	0.771	0.74
170_I	370_E	0.770	0.74
53_H	151_T	0.770	0.74
251_K	267_A	0.769	0.74
182_K	623_V	0.769	0.74
269_R	343_H	0.768	0.74
673_N	677_Q	0.768	0.74
83_T	151_T	0.766	0.73
159_K	163_I	0.766	0.73
598_R	619_R	0.766	0.73
53_H	107_K	0.766	0.73
78_D	107_K	0.765	0.73
430_A	451_I	0.764	0.73
14_D	17_R	0.763	0.73
504_L	547_A	0.760	0.73
365_F	371_F	0.759	0.73
43_Y	49_P	0.759	0.73
129_V	390_F	0.758	0.73
324_E	341_A	0.758	0.73
50_Y	151_T	0.757	0.73
207_M	248_I	0.757	0.73
83_T	106_T	0.756	0.73
210_K	214_R	0.755	0.72
267_A	346_Y	0.754	0.72
214_R	242_P	0.754	0.72
251_K	341_A	0.753	0.72
687_S	706_F	0.753	0.72
50_Y	83_T	0.752	0.72
62_V	192_L	0.751	0.72
241_R	343_H	0.751	0.72
252_M	299_Y	0.750	0.72
413_I	427_T	0.749	0.72
482_K	538_Y	0.748	0.72
58_A	74_G	0.746	0.72
44_R	106_T	0.746	0.72
241_R	267_A	0.744	0.71
44_R	144_D	0.743	0.71
229_V	238_F	0.743	0.71
203_I	206_L	0.743	0.71
366_R	369_L	0.741	0.71
588_R	644_E	0.741	0.71
71_I	74_G	0.740	0.71
678_A	719_R	0.739	0.71
214_R	301_A	0.739	0.71
144_D	167_T	0.738	0.71
267_A	347_K	0.738	0.71
217_Y	319_K	0.738	0.71
83_T	107_K	0.736	0.70
148_N	159_K	0.735	0.70
107_K	147_H	0.731	0.70
421_S	666_Y	0.730	0.70
103_D	126_K	0.730	0.70
475_H	479_Q	0.729	0.70
12_V	75_F	0.728	0.70
54_P	57_V	0.727	0.70
104_G	137_V	0.727	0.70
425_N	481_F	0.726	0.69
77_H	151_T	0.726	0.69
21_S	24_H	0.725	0.69
198_Q	201_Y	0.725	0.69
42_Q	50_Y	0.724	0.69
107_K	151_T	0.723	0.69
668_R	675_V	0.722	0.69
148_N	167_T	0.722	0.69
193_R	211_R	0.721	0.69
54_P	151_T	0.718	0.69
243_K	324_E	0.716	0.68
307_M	330_F	0.715	0.68
81_E	107_K	0.714	0.68
46_S	82_D	0.713	0.68
67_D	70_T	0.713	0.68
20_L	478_R	0.713	0.68
675_V	679_V	0.713	0.68
367_E	371_F	0.712	0.68
283_G	287_T	0.710	0.68
236_A	532_M	0.710	0.68
601_K	604_N	0.709	0.68
153_K	193_R	0.709	0.68
394_V	471_S	0.709	0.68
30_K	72_A	0.708	0.68
34_Y	90_L	0.708	0.68
207_M	319_K	0.707	0.67
467_L	472_Q	0.707	0.67
47_G	53_H	0.706	0.67
254_L	259_F	0.706	0.67
390_F	482_K	0.706	0.67
658_N	687_S	0.706	0.67
109_G	163_I	0.705	0.67
91_K	95_S	0.704	0.67
126_K	137_V	0.704	0.67
241_R	324_E	0.703	0.67
470_T	476_K	0.703	0.67
437_V	720_I	0.703	0.67
145_R	166_E	0.703	0.67
250_R	254_L	0.702	0.67
105_V	108_L	0.701	0.67
50_Y	106_T	0.700	0.67
82_D	159_K	0.700	0.67
105_V	283_G	0.700	0.67
25_I	29_E	0.700	0.67
120_Q	139_L	0.699	0.67
661_I	729_V	0.698	0.66
432_V	449_V	0.698	0.66
230_E	550_L	0.698	0.66
612_V	626_E	0.698	0.66
53_H	106_T	0.697	0.66
678_A	723_I	0.697	0.66
83_T	86_T	0.697	0.66
412_P	441_H	0.697	0.66
81_E	105_V	0.696	0.66
82_D	144_D	0.696	0.66
417_Y	460_P	0.695	0.66
491_E	495_E	0.694	0.66
54_P	107_K	0.693	0.66
199_Q	249_Y	0.693	0.66
152_L	160_Q	0.692	0.66
604_N	660_E	0.692	0.66
307_M	335_I	0.691	0.66
267_A	325_V	0.690	0.66
394_V	409_G	0.688	0.65
581_R	623_V	0.685	0.65
220_E	441_H	0.684	0.65
48_E	53_H	0.684	0.65
672_L	685_N	0.683	0.65
23_E	26_A	0.681	0.65
81_E	104_G	0.678	0.64
422_E	426_K	0.678	0.64
107_K	141_K	0.677	0.64
623_V	641_I	0.677	0.64
91_K	100_M	0.677	0.64
122_E	607_P	0.676	0.64
60_I	71_I	0.676	0.64
356_A	359_E	0.676	0.64
149_M	160_Q	0.675	0.64
257_K	261_E	0.675	0.64
185_W	188_E	0.672	0.63
53_H	81_E	0.670	0.63
270_I	717_V	0.670	0.63
64_L	183_I	0.669	0.63
144_D	151_T	0.669	0.63
78_D	151_T	0.669	0.63
13_I	25_I	0.668	0.63
412_P	442_K	0.667	0.63
128_F	132_A	0.667	0.63
20_L	98_V	0.667	0.63
139_L	180_I	0.667	0.63
497_V	546_V	0.667	0.63
17_R	23_E	0.666	0.63
264_D	346_Y	0.666	0.63
625_R	671_L	0.666	0.63
241_R	341_A	0.665	0.63
436_M	452_L	0.664	0.63
83_T	147_H	0.663	0.62
203_I	259_F	0.663	0.62
264_D	343_H	0.663	0.62
73_G	102_V	0.662	0.62
326_Q	346_Y	0.662	0.62
125_R	460_P	0.662	0.62
378_A	721_K	0.661	0.62
497_V	532_M	0.661	0.62
229_V	234_I	0.660	0.62
41_E	49_P	0.660	0.62
251_K	269_R	0.660	0.62
535_A	540_G	0.659	0.62
135_I	139_L	0.658	0.62
527_S	531_D	0.658	0.62
586_G	591_G	0.657	0.62
234_I	281_V	0.656	0.62
269_R	324_E	0.656	0.62
596_L	621_V	0.655	0.61
189_D	193_R	0.655	0.61
44_R	159_K	0.654	0.61
53_H	82_D	0.653	0.61
521_A	533_Y	0.652	0.61
481_F	622_S	0.652	0.61
21_S	25_I	0.652	0.61
317_G	369_L	0.652	0.61
24_H	27_F	0.651	0.61
243_K	346_Y	0.650	0.61
80_V	89_D	0.649	0.61
322_P	481_F	0.649	0.61
172_A	244_H	0.649	0.61
78_D	102_V	0.647	0.61
120_Q	127_M	0.647	0.61
20_L	24_H	0.647	0.61
676_L	725_D	0.645	0.60
39_H	83_T	0.645	0.60
183_I	661_I	0.645	0.60
264_D	324_E	0.645	0.60
668_R	699_A	0.645	0.60
57_V	77_H	0.644	0.60
164_S	195_L	0.644	0.60
92_E	96_E	0.643	0.60
214_R	240_G	0.642	0.60
53_H	79_V	0.642	0.60
16_A	25_I	0.642	0.60
155_L	160_Q	0.642	0.60
54_P	106_T	0.640	0.60
220_E	224_E	0.639	0.60
496_L	536_V	0.638	0.59
493_G	537_G	0.638	0.59
39_H	47_G	0.635	0.59
124_H	206_L	0.635	0.59
556_K	559_D	0.635	0.59
213_E	265_L	0.634	0.59
675_V	678_A	0.634	0.59
131_M	309_Q	0.633	0.59
172_A	187_L	0.632	0.59
307_M	334_E	0.632	0.59
141_K	145_R	0.632	0.59
514_P	518_Q	0.631	0.59
233_N	470_T	0.631	0.59
42_Q	78_D	0.630	0.59
708_Q	712_H	0.630	0.59
676_L	701_I	0.630	0.59
254_L	257_K	0.629	0.58
102_V	145_R	0.627	0.58
251_K	326_Q	0.625	0.58
689_V	701_I	0.624	0.58
228_R	287_T	0.624	0.58
86_T	705_I	0.623	0.58
672_L	691_G	0.623	0.58
326_Q	343_H	0.621	0.57
486_R	530_E	0.620	0.57
251_K	264_D	0.618	0.57
408_S	442_K	0.617	0.57
46_S	50_Y	0.616	0.57
205_N	208_K	0.616	0.57
500_E	504_L	0.616	0.57
194_Y	433_N	0.615	0.57
66_M	180_I	0.615	0.57
280_A	284_I	0.614	0.57
381_F	386_K	0.612	0.56
81_E	159_K	0.612	0.56
169_E	386_K	0.611	0.56
349_G	352_A	0.611	0.56
105_V	141_K	0.611	0.56
70_T	101_L	0.609	0.56
290_K	397_F	0.608	0.56
216_L	219_D	0.607	0.56
413_I	537_G	0.606	0.56
42_Q	148_N	0.606	0.56
241_R	251_K	0.605	0.55
243_K	347_K	0.604	0.55
656_E	708_Q	0.604	0.55
606_V	731_R	0.603	0.55
412_P	439_L	0.602	0.55
689_V	699_A	0.602	0.55
39_H	46_S	0.601	0.55
318_P	323_L	0.601	0.55
676_L	680_N	0.601	0.55
105_V	109_G	0.601	0.55
57_V	74_G	0.601	0.55
78_D	159_K	0.600	0.55
76_L	90_L	0.600	0.55
714_H	718_E	0.599	0.55
344_W	602_C	0.598	0.55
445_T	712_H	0.598	0.55
128_F	472_Q	0.596	0.54
12_V	59_G	0.596	0.54
127_M	371_F	0.596	0.54
244_H	463_D	0.596	0.54
605_P	624_H	0.595	0.54
279_Y	301_A	0.594	0.54
46_S	107_K	0.593	0.54
47_G	106_T	0.593	0.54
132_A	291_P	0.593	0.54
590_K	644_E	0.593	0.54
637_Q	640_L	0.591	0.54
667_D	670_G	0.591	0.54
438_T	442_K	0.591	0.54
426_K	454_S	0.590	0.54
345_A	359_E	0.589	0.54
310_S	328_R	0.589	0.54
264_D	326_Q	0.589	0.54
678_A	705_I	0.589	0.54
613_G	643_V	0.588	0.53
333_H	338_Y	0.587	0.53
659_V	685_N	0.587	0.53
57_V	107_K	0.586	0.53
44_R	141_K	0.585	0.53
63_D	623_V	0.585	0.53
395_Y	591_G	0.585	0.53
387_I	395_Y	0.584	0.53
519_K	553_K	0.584	0.53
369_L	389_L	0.584	0.53
80_V	86_T	0.583	0.53
22_D	26_A	0.581	0.53
152_L	155_L	0.580	0.52
106_T	144_D	0.580	0.52
415_F	451_I	0.579	0.52
590_K	646_E	0.579	0.52
49_P	53_H	0.579	0.52
78_D	144_D	0.579	0.52
262_I	659_V	0.578	0.52
323_L	402_D	0.577	0.52
60_I	74_G	0.577	0.52
371_F	374_E	0.576	0.52
241_R	247_S	0.576	0.52
47_G	148_N	0.575	0.52
46_S	53_H	0.575	0.52
192_L	255_Q	0.574	0.52
46_S	57_V	0.574	0.52
27_F	97_E	0.574	0.52
39_H	159_K	0.573	0.52
249_Y	468_A	0.573	0.52
135_I	294_G	0.573	0.52
589_V	641_I	0.573	0.52
151_T	159_K	0.573	0.52
267_A	449_V	0.572	0.51
28_V	40_R	0.572	0.51
502_K	589_V	0.572	0.51
149_M	164_S	0.571	0.51
506_F	551_T	0.571	0.51
402_D	422_E	0.570	0.51
218_V	438_T	0.570	0.51
77_H	107_K	0.569	0.51
13_I	16_A	0.569	0.51
270_I	275_I	0.569	0.51
525_N	540_G	0.569	0.51
235_K	726_I	0.569	0.51
623_V	684_T	0.569	0.51
679_V	716_V	0.569	0.51
161_R	165_N	0.569	0.51
292_M	296_F	0.569	0.51
342_A	346_Y	0.568	0.51
140_I	643_V	0.568	0.51
50_Y	57_V	0.567	0.51
120_Q	369_L	0.567	0.51
165_N	195_L	0.566	0.51
267_A	324_E	0.566	0.51
536_V	542_T	0.566	0.51
145_R	163_I	0.565	0.51
498_E	533_Y	0.565	0.51
129_V	341_A	0.565	0.51
555_R	661_I	0.565	0.51
32_Y	55_I	0.564	0.50
110_K	413_I	0.564	0.50
411_V	676_L	0.563	0.50
312_H	328_R	0.562	0.50
432_V	436_M	0.562	0.50
44_R	48_E	0.562	0.50
120_Q	123_N	0.562	0.50
247_S	341_A	0.560	0.50
498_E	508_L	0.560	0.50
222_V	239_S	0.559	0.50
317_G	321_D	0.559	0.50
65_E	345_A	0.559	0.50
427_T	676_L	0.559	0.50
135_I	306_N	0.559	0.50
209_K	266_L	0.559	0.50
124_H	363_S	0.559	0.50
392_D	657_Y	0.559	0.50
673_N	676_L	0.558	0.50
419_I	597_V	0.558	0.50
149_M	199_Q	0.557	0.50
35_A	466_K	0.556	0.49
412_P	436_M	0.555	0.49
247_S	324_E	0.555	0.49
15_K	18_S	0.555	0.49
667_D	671_L	0.555	0.49
189_D	194_Y	0.554	0.49
552_E	555_R	0.553	0.49
246_Y	249_Y	0.553	0.49
52_I	56_Q	0.553	0.49
390_F	445_T	0.553	0.49
531_D	679_V	0.553	0.49
286_H	299_Y	0.552	0.49
279_Y	313_T	0.551	0.49
14_D	24_H	0.551	0.49
184_K	188_E	0.551	0.49
243_K	326_Q	0.551	0.49
218_V	238_F	0.551	0.49
100_M	268_V	0.550	0.49
516_N	554_E	0.550	0.49
196_N	349_G	0.549	0.49
534_A	538_Y	0.549	0.49
107_K	145_R	0.549	0.49
282_L	299_Y	0.549	0.49
217_Y	321_D	0.549	0.49
523_K	552_E	0.549	0.49
104_G	130_A	0.548	0.48
484_Q	487_E	0.548	0.48
82_D	141_K	0.547	0.48
491_E	494_R	0.547	0.48
292_M	314_T	0.547	0.48
247_S	251_K	0.547	0.48
184_K	248_I	0.547	0.48
283_G	296_F	0.546	0.48
171_F	419_I	0.546	0.48
461_S	466_K	0.545	0.48
147_H	159_K	0.545	0.48
680_N	686_I	0.545	0.48
421_S	429_G	0.545	0.48
430_A	476_K	0.544	0.48
605_P	628_C	0.544	0.48
39_H	102_V	0.544	0.48
363_S	367_E	0.543	0.48
164_S	451_I	0.542	0.48
259_F	457_S	0.542	0.48
181_S	597_V	0.542	0.48
616_T	639_R	0.542	0.48
57_V	78_D	0.542	0.48
121_A	389_L	0.542	0.48
34_Y	40_R	0.541	0.48
243_K	341_A	0.540	0.47
141_K	144_D	0.540	0.47
46_S	81_E	0.540	0.47
476_K	479_Q	0.540	0.47
54_P	144_D	0.539	0.47
285_I	288_C	0.539	0.47
490_V	659_V	0.539	0.47
103_D	472_Q	0.538	0.47
411_V	465_V	0.538	0.47
410_S	727_Y	0.537	0.47
98_V	507_E	0.537	0.47
191_A	409_G	0.537	0.47
106_T	167_T	0.536	0.47
475_H	612_V	0.536	0.47
438_T	441_H	0.535	0.47
113_Y	270_I	0.535	0.47
300_I	620_G	0.535	0.47
184_K	267_A	0.535	0.47
126_K	291_P	0.535	0.47
329_T	467_L	0.534	0.47
192_L	286_H	0.534	0.47
494_R	530_E	0.533	0.47
242_P	323_L	0.532	0.46
81_E	141_K	0.532	0.46
426_K	453_T	0.531	0.46
632_K	661_I	0.531	0.46
672_L	703_M	0.531	0.46
638_E	675_V	0.530	0.46
99_A	103_D	0.530	0.46
67_D	333_H	0.530	0.46
302_M	307_M	0.529	0.46
165_N	196_N	0.529	0.46
387_I	393_M	0.529	0.46
211_R	245_I	0.528	0.46
83_T	144_D	0.528	0.46
293_P	447_D	0.528	0.46
149_M	159_K	0.527	0.46
524_F	532_M	0.527	0.46
321_D	427_T	0.527	0.46
451_I	582_K	0.527	0.46
244_H	333_H	0.526	0.46
428_I	454_S	0.526	0.46
377_D	380_E	0.526	0.46
609_D	692_K	0.525	0.46
270_I	557_Q	0.525	0.46
32_Y	483_K	0.525	0.46
116_Q	162_R	0.525	0.46
62_V	283_G	0.524	0.45
663_I	726_I	0.524	0.45
266_L	321_D	0.524	0.45
165_N	623_V	0.524	0.45
13_I	29_E	0.523	0.45
279_Y	299_Y	0.523	0.45
311_L	369_L	0.522	0.45
536_V	546_V	0.522	0.45
28_V	75_F	0.522	0.45
203_I	365_F	0.522	0.45
149_M	155_L	0.522	0.45
264_D	269_R	0.522	0.45
366_R	500_E	0.522	0.45
418_R	531_D	0.521	0.45
101_L	108_L	0.521	0.45
191_A	194_Y	0.521	0.45
244_H	619_R	0.520	0.45
12_V	32_Y	0.520	0.45
39_H	144_D	0.520	0.45
586_G	646_E	0.520	0.45
666_Y	727_Y	0.519	0.45
65_E	128_F	0.518	0.45
187_L	396_V	0.518	0.45
353_N	716_V	0.517	0.45
262_I	630_N	0.516	0.44
243_K	267_A	0.516	0.44
77_H	102_V	0.515	0.44
21_S	26_A	0.514	0.44
193_R	285_I	0.514	0.44
24_H	30_K	0.514	0.44
325_V	621_V	0.514	0.44
20_L	71_I	0.514	0.44
53_H	94_F	0.513	0.44
609_D	625_R	0.513	0.44
426_K	470_T	0.512	0.44
33_L	40_R	0.512	0.44
92_E	577_Y	0.512	0.44
306_N	313_T	0.512	0.44
156_P	648_E	0.512	0.44
340_V	373_N	0.511	0.44
47_G	144_D	0.511	0.44
662_E	732_V	0.511	0.44
709_N	722_Q	0.511	0.44
105_V	373_N	0.511	0.44
78_D	152_L	0.510	0.44
48_E	147_H	0.510	0.44
461_S	481_F	0.510	0.44
168_L	191_A	0.510	0.44
247_S	326_Q	0.510	0.44
39_H	167_T	0.510	0.44
180_I	348_E	0.509	0.44
269_R	347_K	0.509	0.44
217_Y	266_L	0.508	0.43
82_D	102_V	0.508	0.43
76_L	80_V	0.508	0.43
629_P	661_I	0.508	0.43
501_I	550_L	0.506	0.43
17_R	29_E	0.506	0.43
167_T	187_L	0.506	0.43
374_E	377_D	0.506	0.43
296_F	402_D	0.506	0.43
191_A	468_A	0.506	0.43
244_H	348_E	0.505	0.43
132_A	189_D	0.504	0.43
449_V	686_I	0.504	0.43
145_R	171_F	0.504	0.43
495_E	499_K	0.503	0.43
289_W	485_R	0.502	0.43
34_Y	37_D	0.502	0.43
221_V	266_L	0.502	0.43
284_I	508_L	0.501	0.43
516_N	519_K	0.501	0.43
526_F	541_I	0.500	0.43
689_V	720_I	0.500	0.43
78_D	163_I	0.500	0.43

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1vj7A	1	0.4564	100	0.517	Contact Map
3l9dA	1	0.2534	100	0.771	Contact Map
4yf1A	2	0.2098	100	0.826	Contact Map
3nr1A	2	0.2371	100	0.834	Contact Map
2be3A	2	0.2616	100	0.838	Contact Map
3nqwA	2	0.233	100	0.84	Contact Map
2ekiA	1	0.1144	99.9	0.924	Contact Map
3hvzA	2	0.0872	99.7	0.937	Contact Map
1wxqA	1	0.2902	99.5	0.947	Contact Map
3j7y7	1	0.3351	99.4	0.948	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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