GREMLIN Database
YFKR - Putative spore germination protein YfkR
UniProt: O35028 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 384 (357)
Sequences: 2222 (1915)
Seq/√Len: 101.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
280_T365_H5.0631.00
282_E367_V4.2701.00
110_E114_R4.0441.00
230_H325_R4.0221.00
40_K115_D3.9141.00
110_E140_R3.4431.00
46_R144_R3.4351.00
250_L294_S3.4001.00
316_K320_I3.3261.00
107_I139_S2.9971.00
142_E145_D2.9401.00
193_V225_I2.9011.00
284_R369_I2.8001.00
312_N370_V2.7421.00
259_I311_L2.7201.00
279_M336_F2.6621.00
144_R148_N2.4291.00
316_K368_P2.3991.00
279_M362_M2.3831.00
116_G220_D2.3571.00
222_L225_I2.3451.00
286_K373_E2.3341.00
278_S363_E2.3311.00
215_A222_L2.3311.00
283_I319_V2.3231.00
49_M90_L2.3041.00
327_Q359_Y2.2671.00
44_Q79_S2.2581.00
178_F189_P2.2501.00
138_V215_A2.2421.00
47_V86_A2.2401.00
233_A322_T2.1871.00
330_K360_K2.1831.00
326_L359_Y2.1221.00
278_S365_H2.1011.00
323_V364_V2.0771.00
48_A143_A2.0491.00
214_L231_M2.0331.00
113_A138_V2.0201.00
224_D329_L1.9721.00
108_I120_V1.9521.00
35_S158_A1.9441.00
326_L333_P1.9411.00
354_E357_E1.8771.00
46_R79_S1.8721.00
280_T367_V1.8651.00
122_D126_R1.8611.00
326_L334_A1.8531.00
136_I178_F1.8451.00
281_I336_F1.8381.00
78_A89_K1.7741.00
214_L234_A1.7561.00
137_L194_I1.7561.00
271_A280_T1.7491.00
39_D143_A1.7421.00
178_F191_A1.7281.00
190_Y234_A1.7211.00
109_G143_A1.7091.00
347_T351_L1.7081.00
41_K79_S1.7051.00
38_I112_M1.7051.00
305_Y308_Q1.7001.00
337_Q355_W1.6891.00
44_Q81_T1.6581.00
88_N260_Q1.6461.00
33_V98_I1.6421.00
87_N100_T1.6311.00
39_D109_G1.5831.00
37_A143_A1.5791.00
36_S103_R1.5641.00
227_K230_H1.5491.00
285_A370_V1.5421.00
259_I287_G1.5371.00
279_M340_T1.5351.00
185_I352_K1.5351.00
193_V222_L1.5211.00
46_R77_S1.5051.00
270_A277_L1.4881.00
138_V217_F1.4801.00
233_A315_I1.4691.00
35_S147_L1.4651.00
113_A217_F1.4501.00
282_E369_I1.4461.00
307_I372_I1.4441.00
323_V366_V1.4201.00
186_G337_Q1.4091.00
286_K371_T1.4071.00
77_S144_R1.4031.00
109_G112_M1.4001.00
306_I310_A1.3971.00
276_K363_E1.3961.00
314_T318_D1.3931.00
188_D331_A1.3911.00
272_E277_L1.3871.00
140_R195_S1.3861.00
216_I333_P1.3841.00
132_L176_S1.3680.99
268_F279_M1.3620.99
312_N316_K1.3610.99
41_K46_R1.3520.99
308_Q312_N1.3450.99
81_T85_E1.3390.99
224_D331_A1.3370.99
161_I194_I1.3360.99
322_T326_L1.3340.99
314_T317_K1.3260.99
108_I117_V1.3130.99
319_V366_V1.3110.99
108_I113_A1.3000.99
11_P15_C1.2920.99
80_G86_A1.2920.99
145_D148_N1.2860.99
239_N266_A1.2830.99
46_R142_E1.2780.99
188_D356_E1.2640.99
237_L334_A1.2530.99
36_S124_L1.2460.99
324_H327_Q1.2240.99
195_S212_D1.2170.99
327_Q355_W1.2140.99
30_I99_N1.2140.99
355_W359_Y1.2100.99
309_K312_N1.1840.98
197_S210_K1.1820.98
234_A333_P1.1740.98
139_S146_I1.1680.98
233_A326_L1.1640.98
237_L281_I1.1620.98
311_L370_V1.1590.98
84_R88_N1.1540.98
266_A283_I1.1540.98
149_T196_A1.1480.98
340_T347_T1.1460.98
126_R376_G1.1460.98
33_V100_T1.1430.98
84_R290_M1.1430.98
84_R260_Q1.1390.98
14_I17_L1.1390.98
104_R162_R1.1380.98
340_T344_T1.1350.98
300_E303_Q1.1340.98
267_S282_E1.1230.98
48_A77_S1.1190.98
38_I83_I1.1170.98
216_I329_L1.1090.98
125_T179_M1.1080.98
18_L21_C1.1060.98
287_G311_L1.1040.98
45_Y112_M1.1020.98
103_R130_N1.1010.98
107_I137_L1.0990.97
84_R123_I1.0970.97
80_G85_E1.0940.97
34_V52_P1.0920.97
50_Q157_P1.0870.97
297_E300_E1.0830.97
270_A343_S1.0820.97
195_S210_K1.0750.97
288_I374_Q1.0730.97
48_A75_V1.0730.97
111_D143_A1.0680.97
73_W157_P1.0670.97
257_A307_I1.0650.97
31_A51_I1.0500.97
218_K223_M1.0460.97
304_Y308_Q1.0380.96
270_A279_M1.0310.96
54_V154_E1.0300.96
113_A215_A1.0260.96
285_A315_I1.0180.96
118_A220_D1.0180.96
80_G89_K1.0180.96
78_A90_L1.0170.96
245_E260_Q1.0130.96
270_A344_T1.0080.96
106_V134_A1.0050.96
269_H280_T1.0040.96
140_R225_I0.9980.96
230_H321_S0.9960.96
188_D359_Y0.9950.95
234_A238_L0.9950.95
237_L319_V0.9930.95
28_N132_L0.9910.95
273_K278_S0.9830.95
338_D341_I0.9780.95
168_A241_A0.9760.95
310_A313_R0.9670.95
320_I366_V0.9620.95
109_G139_S0.9590.94
186_G335_G0.9590.94
349_N352_K0.9570.94
37_A142_E0.9540.94
227_K231_M0.9500.94
191_A217_F0.9430.94
82_T256_Q0.9400.94
356_E359_Y0.9340.94
327_Q360_K0.9340.94
97_T129_Q0.9340.94
292_N296_Y0.9320.94
137_L192_P0.9310.94
102_H131_R0.9300.94
313_R316_K0.9280.93
339_R342_R0.9260.93
93_S208_N0.9250.93
127_N290_M0.9210.93
313_R317_K0.9190.93
81_T256_Q0.9150.93
37_A109_G0.9100.93
106_V124_L0.9030.93
7_K18_L0.9000.92
246_F318_D0.8960.92
268_F281_I0.8940.92
320_I324_H0.8900.92
324_H328_K0.8890.92
336_F364_V0.8880.92
269_H282_E0.8870.92
338_D342_R0.8840.92
223_M331_A0.8840.92
111_D114_R0.8840.92
73_W156_F0.8840.92
358_V361_D0.8830.92
93_S210_K0.8790.91
113_A222_L0.8780.91
57_L72_T0.8720.91
50_Q73_W0.8700.91
110_E225_I0.8690.91
340_T348_K0.8660.91
345_A349_N0.8660.91
117_V178_F0.8630.91
283_I368_P0.8590.91
37_A48_A0.8580.90
316_K366_V0.8560.90
270_A339_R0.8530.90
78_A86_A0.8520.90
41_K44_Q0.8510.90
309_K313_R0.8510.90
178_F182_L0.8480.90
277_L362_M0.8460.90
106_V136_I0.8460.90
226_F230_H0.8450.90
25_T30_I0.8450.90
233_A319_V0.8440.90
31_A153_L0.8420.90
113_A116_G0.8370.89
272_E344_T0.8360.89
315_I319_V0.8310.89
36_S49_M0.8300.89
146_I194_I0.8280.89
15_C19_T0.8240.89
109_G138_V0.8180.88
38_I47_V0.8110.88
136_I191_A0.8110.88
105_T137_L0.8110.88
344_T347_T0.8040.87
339_R343_S0.8000.87
146_I196_A0.7980.87
271_A278_S0.7970.87
317_K321_S0.7960.87
187_S335_G0.7930.87
24_R32_F0.7920.87
114_R217_F0.7910.87
305_Y309_K0.7880.86
36_S106_V0.7860.86
84_R127_N0.7860.86
218_K331_A0.7820.86
7_K11_P0.7790.86
236_M241_A0.7790.86
325_R329_L0.7790.86
347_T350_L0.7760.85
164_L211_I0.7730.85
176_S180_S0.7730.85
138_V222_L0.7720.85
216_I226_F0.7690.85
323_V334_A0.7690.85
286_K374_Q0.7690.85
257_A292_N0.7680.85
137_L165_A0.7650.85
29_D163_E0.7630.85
233_A236_M0.7620.84
10_L13_L0.7620.84
217_F222_L0.7620.84
184_E338_D0.7610.84
135_L162_R0.7600.84
35_S105_T0.7570.84
82_T291_E0.7560.84
235_L240_Q0.7540.84
143_A147_L0.7530.84
345_A348_K0.7520.84
76_D90_L0.7500.84
78_A93_S0.7480.83
40_K111_D0.7470.83
84_R291_E0.7460.83
53_L56_Q0.7420.83
6_Y302_D0.7410.83
174_F177_R0.7400.83
236_M285_A0.7390.83
50_Q131_R0.7370.82
26_E96_R0.7370.82
178_F217_F0.7350.82
323_V327_Q0.7330.82
139_S143_A0.7310.82
237_L266_A0.7310.82
315_I370_V0.7310.82
160_M164_L0.7310.82
193_V215_A0.7290.82
268_F339_R0.7290.82
35_S50_Q0.7290.82
32_F99_N0.7280.82
116_G217_F0.7260.81
260_Q290_M0.7250.81
297_E301_N0.7210.81
108_I138_V0.7190.81
190_Y333_P0.7180.81
301_N305_Y0.7170.81
303_Q306_I0.7130.80
251_P310_A0.7110.80
7_K15_C0.7050.80
91_Q128_P0.7030.79
38_I106_V0.7010.79
272_E347_T0.7000.79
289_I298_T0.6960.79
36_S47_V0.6940.79
109_G222_L0.6940.79
28_N160_M0.6930.78
6_Y17_L0.6910.78
82_T258_S0.6910.78
26_E102_H0.6900.78
259_I372_I0.6870.78
233_A318_D0.6860.78
159_E163_E0.6850.78
270_A336_F0.6840.77
103_R134_A0.6830.77
117_V217_F0.6820.77
51_I94_L0.6820.77
100_T106_V0.6800.77
49_M87_N0.6790.77
117_V220_D0.6780.77
351_L358_V0.6720.76
218_K356_E0.6710.76
140_R193_V0.6710.76
79_S83_I0.6690.76
257_A287_G0.6670.76
76_D94_L0.6660.76
89_K92_T0.6660.76
188_D333_P0.6640.75
249_D256_Q0.6620.75
85_E247_I0.6610.75
355_W360_K0.6600.75
284_R371_T0.6580.75
19_T22_W0.6570.75
38_I45_Y0.6560.75
49_M100_T0.6550.74
248_V310_A0.6490.74
181_D187_S0.6460.73
326_L329_L0.6450.73
32_F73_W0.6440.73
33_V90_L0.6430.73
31_A94_L0.6430.73
17_L309_K0.6410.73
105_T161_I0.6410.73
274_N284_R0.6400.73
48_A144_R0.6390.73
124_L175_L0.6390.73
35_S159_E0.6380.72
48_A139_S0.6310.72
15_C18_L0.6300.72
92_T228_D0.6270.71
7_K115_D0.6250.71
37_A144_R0.6230.71
84_R128_P0.6220.71
353_K357_E0.6220.71
122_D291_E0.6200.70
177_R181_D0.6200.70
287_G308_Q0.6180.70
119_P311_L0.6180.70
40_K45_Y0.6180.70
50_Q75_V0.6170.70
168_A232_T0.6160.70
268_F362_M0.6160.70
189_P337_Q0.6160.70
140_R222_L0.6140.70
37_A107_I0.6120.69
139_S213_G0.6120.69
48_A147_L0.6110.69
61_T350_L0.6100.69
223_M329_L0.6090.69
112_M120_V0.6090.69
323_V359_Y0.6070.69
15_C321_S0.6060.69
189_P335_G0.6050.68
277_L340_T0.6040.68
48_A109_G0.6030.68
175_L178_F0.6030.68
287_G370_V0.5990.68
319_V322_T0.5980.68
159_E162_R0.5980.68
108_I121_F0.5980.68
127_N260_Q0.5950.67
179_M378_L0.5940.67
322_T325_R0.5930.67
141_G213_G0.5930.67
276_K361_D0.5920.67
187_S338_D0.5920.67
138_V191_A0.5890.66
236_M315_I0.5890.66
235_L377_V0.5890.66
151_V154_E0.5870.66
260_Q288_I0.5870.66
234_A322_T0.5850.66
48_A111_D0.5840.66
226_F234_A0.5840.66
327_Q362_M0.5840.66
10_L17_L0.5820.66
134_A176_S0.5810.65
113_A117_V0.5810.65
110_E193_V0.5810.65
34_V176_S0.5790.65
7_K14_I0.5780.65
235_L239_N0.5780.65
114_R302_D0.5770.65
23_D29_D0.5760.65
212_D228_D0.5740.64
232_T318_D0.5730.64
8_C12_L0.5730.64
224_D359_Y0.5720.64
45_Y120_V0.5720.64
27_I72_T0.5720.64
88_N91_Q0.5720.64
122_D376_G0.5720.64
285_A310_A0.5710.64
24_R154_E0.5700.64
173_V181_D0.5700.64
9_V275_G0.5690.64
262_Q288_I0.5680.64
165_A331_A0.5680.64
16_I114_R0.5680.64
322_T333_P0.5660.63
52_P155_Q0.5640.63
261_L264_S0.5570.62
273_K276_K0.5570.62
190_Y214_L0.5560.62
107_I143_A0.5560.62
50_Q158_A0.5550.62
330_K357_E0.5550.62
96_R154_E0.5540.62
38_I108_I0.5510.61
90_L183_V0.5510.61
19_T23_D0.5510.61
28_N53_L0.5500.61
149_T209_L0.5490.61
92_T169_T0.5480.61
217_F220_D0.5470.61
101_S189_P0.5450.60
25_T82_T0.5440.60
99_N104_R0.5430.60
251_P255_G0.5430.60
229_E318_D0.5430.60
114_R225_I0.5430.60
107_I162_R0.5420.60
15_C249_D0.5410.60
159_E166_I0.5410.60
149_T159_E0.5410.60
192_P211_I0.5410.60
232_T236_M0.5400.60
117_V248_V0.5390.60
37_A50_Q0.5390.60
110_E141_G0.5380.59
80_G247_I0.5370.59
7_K17_L0.5370.59
216_I275_G0.5370.59
137_L161_I0.5370.59
226_F325_R0.5370.59
216_I331_A0.5350.59
241_A264_S0.5350.59
91_Q98_I0.5340.59
11_P14_I0.5330.59
17_L321_S0.5320.59
354_E358_V0.5310.58
277_L351_L0.5290.58
216_I326_L0.5290.58
236_M246_F0.5290.58
72_T157_P0.5290.58
95_S151_V0.5290.58
8_C11_P0.5280.58
296_Y303_Q0.5280.58
312_N369_I0.5280.58
75_V157_P0.5260.58
7_K371_T0.5260.58
251_P254_M0.5260.58
250_L257_A0.5260.58
121_F136_I0.5260.58
102_H143_A0.5240.58
94_L98_I0.5240.58
186_G189_P0.5240.58
336_F359_Y0.5240.58
38_I86_A0.5210.57
22_W348_K0.5210.57
41_K111_D0.5210.57
261_L287_G0.5200.57
114_R222_L0.5190.57
109_G142_E0.5190.57
218_K302_D0.5180.57
181_D248_V0.5170.57
88_N127_N0.5170.57
237_L323_V0.5150.56
95_S164_L0.5140.56
135_L172_P0.5130.56
241_A244_P0.5130.56
51_I153_L0.5130.56
96_R342_R0.5130.56
34_V211_I0.5120.56
311_L314_T0.5110.56
51_I76_D0.5100.55
234_A334_A0.5100.55
49_M130_N0.5100.55
32_F175_L0.5100.55
261_L285_A0.5080.55
71_K150_D0.5080.55
32_F54_V0.5080.55
30_I101_S0.5070.55
319_V368_P0.5050.55
232_T334_A0.5050.55
152_Q340_T0.5050.55
133_T175_L0.5040.55
284_R313_R0.5030.54
20_G126_R0.5030.54
6_Y18_L0.5030.54
305_Y352_K0.5030.54
226_F322_T0.5020.54
43_D255_G0.5020.54
277_L347_T0.5010.54
76_D100_T0.5010.54
37_A148_N0.5010.54
8_C310_A0.5000.54
247_I258_S0.5000.54
248_V314_T0.5000.54
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3n54B 5 0.7891 100 0.226 Contact Map
3utkA 1 0.2083 27.1 0.964 Contact Map
3zbiC 1 0.0703 24.9 0.965 Contact Map
4ng7A 1 0.6979 23.6 0.965 Contact Map
4n6kA 1 0.6927 17 0.967 Contact Map
3wfdC 1 0.3333 15.2 0.968 Contact Map
4o8mA 4 0.6849 10 0.97 Contact Map
4n6dA 1 0.6719 8.5 0.971 Contact Map
4fybB 1 0.375 8.3 0.971 Contact Map
2m1jA 1 0.0781 7.2 0.972 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0111 seconds.