YODQ - BACSU - GREMLIN Contacts

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YODQ - Uncharacterized metallohydrolase YodQ

UniProt:	O34984	Sequences: MRMQDIERKVIEWLDQHSAKAIRLLKRLIGEKSTLGSEFNAQAVVLEKLRQFHMDIDVWEPSIKQLKQHPYFKSNRSDFHESPNIVAKKTGAGGGRSLILNGHIDVVPEGSVKDWKYEPYQAVEENGKIYGRGSTDMKGGNTALLFALEALHACDVKLKGDVLFQSVVDEECGGAGTLSAIMRGYRADGALIPEPTNMKLFIKQQGSMWFRITVKGLSAHGGTRYEGVSAIEKSMHVITAIQELEKVRNARISDPLYDNIPIPVPVNIGTISGGAWPSSVADRVVIEGRCGIAPHEKPEAVKLELENWLKDLEYHDEWFKRHPVQVEWFGAQWLPNDLPDDHPLISVLQSAYQKMKQTEPIIEASPWGTDGGLLYHAGDTPVIVFGPGETKTAHQANEYIEVEAMIESAKIIALFVMDWCGLHTDGEDADAQVNKE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	436 (361)
Sequences:	27228 (19109)
Seq/√Len:	1005.8

ECOLI - YGEY DAPE ARGE PEPT ABGA ABGB PEPD ALLC
BACSU - YODQ FAPD YQJE YHAA PEPT YTNL YXEP AMHX DAPEL PEPVL ALLC YQJN
HALSA - Q9HS25
SULSO - Q97Y12 Q97ZB7 CBPX1 Q97V97 LYSK CBPX2 Q97VB6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
88_K	163_L	3.217	1.00
213_T	283_R	3.068	1.00
46_L	50_R	2.885	1.00
213_T	285_V	2.791	1.00
27_R	44_V	2.786	1.00
219_A	227_G	2.726	1.00
128_K	399_Y	2.669	1.00
90_T	161_D	2.573	1.00
97_S	161_D	2.413	1.00
306_E	310_K	2.405	1.00
211_R	285_V	2.399	1.00
302_K	306_E	2.382	1.00
215_K	325_Q	2.375	1.00
214_V	237_V	2.371	1.00
354_K	418_D	2.328	1.00
350_S	418_D	2.321	1.00
354_K	414_L	2.301	1.00
48_K	51_Q	2.280	1.00
215_K	283_R	2.266	1.00
46_L	58_V	2.251	1.00
150_A	413_A	2.219	1.00
233_K	322_H	2.178	1.00
52_F	149_E	2.175	1.00
272_S	285_V	2.173	1.00
234_S	271_I	2.171	1.00
97_S	163_L	2.156	1.00
215_K	323_P	2.152	1.00
211_R	287_E	2.146	1.00
303_L	307_N	2.140	1.00
88_K	161_D	2.099	1.00
234_S	284_V	2.099	1.00
99_I	187_A	2.033	1.00
270_T	287_E	2.028	1.00
18_S	406_I	1.996	1.00
234_S	286_I	1.979	1.00
44_V	48_K	1.971	1.00
31_E	44_V	1.945	1.00
20_K	149_E	1.939	1.00
213_T	325_Q	1.931	1.00
49_L	87_A	1.927	1.00
213_T	327_E	1.925	1.00
39_F	43_A	1.893	1.00
349_Q	353_Q	1.889	1.00
236_H	239_T	1.882	1.00
235_M	238_I	1.880	1.00
150_A	154_C	1.871	1.00
117_Y	125_E	1.840	1.00
116_K	397_N	1.784	1.00
211_R	327_E	1.748	1.00
310_K	314_Y	1.734	1.00
47_E	51_Q	1.733	1.00
178_L	182_M	1.732	1.00
355_M	414_L	1.732	1.00
348_L	415_F	1.717	1.00
43_A	47_E	1.716	1.00
40_N	43_A	1.715	1.00
48_K	52_F	1.696	1.00
21_A	409_A	1.668	1.00
237_V	309_L	1.643	1.00
24_L	48_K	1.642	1.00
118_E	121_Q	1.641	1.00
304_E	307_N	1.638	1.00
228_V	233_K	1.623	1.00
149_E	153_A	1.617	1.00
44_V	47_E	1.605	1.00
299_E	303_L	1.603	1.00
414_L	417_M	1.598	1.00
353_Q	359_E	1.594	1.00
26_K	30_G	1.593	1.00
235_M	239_T	1.583	1.00
230_A	284_V	1.572	1.00
23_R	27_R	1.563	1.00
54_M	89_K	1.545	1.00
27_R	30_G	1.544	1.00
217_L	228_V	1.542	1.00
143_A	408_S	1.535	1.00
42_Q	104_I	1.530	1.00
27_R	40_N	1.523	1.00
21_A	146_F	1.518	1.00
273_G	284_V	1.516	1.00
232_E	242_Q	1.488	1.00
218_S	282_D	1.486	1.00
297_K	300_A	1.482	1.00
46_L	85_I	1.476	1.00
346_S	349_Q	1.475	1.00
39_F	83_P	1.469	1.00
19_A	23_R	1.460	1.00
47_E	50_R	1.447	1.00
351_A	418_D	1.447	1.00
55_D	90_T	1.446	1.00
45_V	104_I	1.440	1.00
48_K	149_E	1.438	1.00
240_A	311_D	1.437	1.00
99_I	165_Q	1.432	1.00
93_G	159_K	1.430	1.00
127_G	403_E	1.420	1.00
414_L	418_D	1.414	1.00
300_A	304_E	1.407	1.00
96_R	188_D	1.406	1.00
347_V	418_D	1.401	1.00
27_R	31_E	1.397	1.00
50_R	56_I	1.384	1.00
99_I	190_A	1.375	1.00
240_A	308_W	1.359	1.00
214_V	234_S	1.343	1.00
210_F	288_G	1.339	1.00
179_S	182_M	1.330	1.00
30_G	124_E	1.317	1.00
262_I	294_P	1.311	1.00
236_H	315_H	1.304	1.00
303_L	306_E	1.300	1.00
23_R	26_K	1.279	1.00
407_E	410_K	1.277	1.00
125_E	128_K	1.272	1.00
139_G	400_I	1.269	1.00
152_H	155_D	1.269	1.00
33_S	41_A	1.269	1.00
22_I	26_K	1.268	1.00
264_V	301_V	1.262	1.00
302_K	328_W	1.261	1.00
102_G	137_M	1.260	1.00
50_R	58_V	1.259	1.00
179_S	183_R	1.254	1.00
212_I	286_I	1.241	1.00
211_R	329_F	1.240	1.00
46_L	56_I	1.235	1.00
124_E	402_V	1.235	1.00
24_L	146_F	1.235	1.00
307_N	311_D	1.232	1.00
351_A	414_L	1.220	1.00
57_D	88_K	1.219	1.00
20_K	23_R	1.214	1.00
43_A	58_V	1.213	1.00
302_K	330_G	1.208	1.00
406_I	410_K	1.204	1.00
24_L	44_V	1.199	1.00
97_S	188_D	1.194	1.00
231_I	273_G	1.193	1.00
352_Y	411_I	1.189	1.00
403_E	407_E	1.184	1.00
375_Y	380_T	1.181	1.00
43_A	46_L	1.175	1.00
214_V	233_K	1.174	1.00
313_E	324_V	1.173	1.00
92_A	159_K	1.170	1.00
35_L	172_C	1.167	1.00
89_K	152_H	1.166	1.00
21_A	142_T	1.160	1.00
154_C	413_A	1.149	1.00
350_S	354_K	1.149	1.00
355_M	410_K	1.147	1.00
18_S	22_I	1.143	1.00
208_M	298_P	1.140	1.00
100_L	144_L	1.140	1.00
346_S	350_S	1.137	1.00
26_K	122_A	1.135	1.00
139_G	405_M	1.132	1.00
148_L	164_F	1.127	1.00
300_A	303_L	1.120	1.00
29_I	131_G	1.118	1.00
307_N	310_K	1.116	1.00
347_V	351_A	1.112	1.00
231_I	271_I	1.110	1.00
18_S	403_E	1.105	1.00
115_W	118_E	1.100	1.00
28_L	41_A	1.097	1.00
200_L	203_K	1.096	1.00
30_G	121_Q	1.096	1.00
26_K	402_V	1.093	1.00
100_L	416_V	1.087	1.00
238_I	286_I	1.075	1.00
117_Y	123_V	1.070	1.00
29_I	134_S	1.066	1.00
128_K	401_E	1.066	1.00
27_R	48_K	1.065	1.00
197_N	393_A	1.064	1.00
31_E	40_N	1.057	1.00
268_I	288_G	1.051	1.00
401_E	404_A	1.051	1.00
193_P	412_I	1.048	1.00
294_P	297_K	1.045	1.00
342_H	346_S	1.044	1.00
26_K	124_E	1.043	1.00
351_A	355_M	1.040	1.00
240_A	312_L	1.039	1.00
24_L	149_E	1.034	1.00
54_M	87_A	1.034	1.00
45_V	141_N	1.027	1.00
139_G	195_P	1.027	1.00
124_E	127_G	1.025	1.00
42_Q	85_I	1.023	1.00
228_V	322_H	1.022	1.00
348_L	383_I	1.017	1.00
306_E	326_V	1.015	1.00
349_Q	362_I	1.014	1.00
40_N	44_V	1.012	1.00
244_L	304_E	1.012	1.00
309_L	324_V	1.002	1.00
20_K	24_L	0.999	1.00
119_P	122_A	0.996	1.00
144_L	164_F	0.990	1.00
241_I	305_L	0.988	1.00
32_K	37_S	0.986	1.00
96_R	160_G	0.986	1.00
350_S	353_Q	0.985	1.00
178_L	373_L	0.981	1.00
304_E	308_W	0.978	1.00
117_Y	121_Q	0.976	1.00
146_F	149_E	0.976	1.00
154_C	417_M	0.975	1.00
210_F	302_K	0.975	1.00
308_W	312_L	0.971	1.00
127_G	401_E	0.968	1.00
239_T	243_E	0.965	1.00
271_I	284_V	0.964	1.00
240_A	243_E	0.962	1.00
55_D	88_K	0.959	1.00
413_A	417_M	0.957	1.00
211_R	277_P	0.950	1.00
110_G	126_N	0.950	1.00
236_H	240_A	0.944	1.00
276_W	279_S	0.941	1.00
28_L	44_V	0.941	1.00
353_Q	358_T	0.939	1.00
102_G	141_N	0.935	1.00
308_W	311_D	0.933	1.00
147_A	413_A	0.931	1.00
104_I	166_S	0.928	1.00
410_K	414_L	0.926	1.00
232_E	238_I	0.922	1.00
238_I	268_I	0.921	1.00
163_L	187_A	0.921	1.00
277_P	287_E	0.920	1.00
42_Q	46_L	0.920	1.00
104_I	141_N	0.916	1.00
36_G	169_D	0.914	1.00
91_G	161_D	0.912	1.00
84_N	168_V	0.912	1.00
21_A	405_M	0.911	1.00
49_L	145_L	0.910	1.00
189_G	419_W	0.907	1.00
20_K	48_K	0.902	1.00
114_D	117_Y	0.902	1.00
117_Y	120_Y	0.897	1.00
351_A	354_K	0.894	1.00
215_K	282_D	0.891	1.00
147_A	412_I	0.888	1.00
341_D	344_L	0.887	1.00
347_V	350_S	0.887	1.00
311_D	315_H	0.886	1.00
189_G	344_L	0.880	1.00
53_H	56_I	0.879	1.00
203_K	364_A	0.871	1.00
409_A	413_A	0.870	1.00
310_K	313_E	0.868	1.00
111_S	114_D	0.866	1.00
117_Y	122_A	0.865	1.00
52_F	152_H	0.865	1.00
37_S	40_N	0.865	1.00
212_I	237_V	0.864	1.00
232_E	235_M	0.863	1.00
114_D	118_E	0.862	1.00
272_S	275_A	0.862	1.00
236_H	243_E	0.860	1.00
223_T	226_E	0.860	1.00
154_C	157_K	0.859	1.00
89_K	148_L	0.852	1.00
212_I	309_L	0.852	1.00
232_E	243_E	0.851	1.00
150_A	410_K	0.850	1.00
54_M	152_H	0.849	1.00
238_I	271_I	0.843	1.00
404_A	407_E	0.843	1.00
236_H	242_Q	0.841	1.00
56_I	87_A	0.841	1.00
89_K	158_L	0.841	1.00
299_E	302_K	0.837	1.00
391_K	397_N	0.835	1.00
33_S	138_K	0.833	1.00
41_A	104_I	0.828	1.00
311_D	314_Y	0.827	1.00
86_V	163_L	0.825	1.00
109_E	120_Y	0.824	1.00
234_S	238_I	0.822	1.00
307_N	314_Y	0.821	1.00
48_K	145_L	0.819	1.00
268_I	286_I	0.819	1.00
54_M	148_L	0.817	1.00
403_E	406_I	0.814	1.00
343_P	346_S	0.813	1.00
191_L	415_F	0.812	1.00
27_R	47_E	0.807	1.00
206_G	292_I	0.804	1.00
150_A	409_A	0.799	1.00
190_A	380_T	0.797	1.00
343_P	347_V	0.796	1.00
295_H	376_H	0.794	1.00
400_I	405_M	0.792	1.00
24_L	142_T	0.791	1.00
209_W	289_R	0.789	1.00
116_K	125_E	0.783	1.00
25_L	129_I	0.781	1.00
231_I	284_V	0.780	1.00
292_I	298_P	0.780	1.00
205_Q	208_M	0.775	1.00
380_T	386_G	0.773	1.00
137_M	140_G	0.772	1.00
30_G	122_A	0.769	1.00
163_L	186_R	0.767	1.00
347_V	415_F	0.767	1.00
345_I	349_Q	0.765	1.00
405_M	409_A	0.760	1.00
146_F	409_A	0.760	1.00
52_F	145_L	0.760	1.00
382_V	385_F	0.760	1.00
190_A	378_G	0.758	1.00
348_L	411_I	0.753	1.00
148_L	152_H	0.744	1.00
106_V	120_Y	0.744	1.00
141_N	166_S	0.743	1.00
296_E	300_A	0.743	1.00
125_E	130_Y	0.736	1.00
100_L	147_A	0.736	1.00
382_V	386_G	0.735	1.00
144_L	193_P	0.733	1.00
266_V	290_C	0.732	1.00
34_T	108_P	0.731	1.00
42_Q	83_P	0.731	1.00
147_A	409_A	0.728	1.00
298_P	334_L	0.727	1.00
230_A	281_A	0.727	1.00
334_L	376_H	0.727	1.00
122_A	129_I	0.726	1.00
295_H	299_E	0.724	1.00
373_L	377_A	0.723	1.00
45_V	166_S	0.722	1.00
36_G	172_C	0.721	1.00
123_V	126_N	0.720	1.00
24_L	27_R	0.719	1.00
150_A	153_A	0.716	1.00
143_A	147_A	0.712	1.00
22_I	124_E	0.711	1.00
298_P	302_K	0.711	1.00
217_L	395_Q	0.710	1.00
214_V	286_I	0.709	1.00
177_T	181_I	0.707	1.00
45_V	145_L	0.703	1.00
208_M	302_K	0.701	1.00
51_Q	149_E	0.700	1.00
201_F	205_Q	0.699	1.00
239_T	242_Q	0.699	1.00
98_L	189_G	0.699	1.00
143_A	412_I	0.696	1.00
143_A	409_A	0.695	1.00
351_A	415_F	0.694	1.00
210_F	305_L	0.693	1.00
378_G	381_P	0.692	1.00
352_Y	355_M	0.689	1.00
34_T	37_S	0.688	1.00
200_L	346_S	0.687	1.00
22_I	402_V	0.687	1.00
290_C	301_V	0.687	1.00
381_P	386_G	0.686	1.00
93_G	161_D	0.685	1.00
89_K	164_F	0.685	1.00
329_F	332_Q	0.683	1.00
24_L	28_L	0.681	1.00
28_L	141_N	0.680	1.00
299_E	330_G	0.678	1.00
387_P	400_I	0.677	1.00
241_I	266_V	0.675	1.00
391_K	395_Q	0.673	1.00
98_L	416_V	0.673	1.00
312_L	315_H	0.672	1.00
165_Q	180_A	0.670	1.00
91_G	94_G	0.669	1.00
94_G	161_D	0.667	1.00
201_F	204_Q	0.666	1.00
149_E	152_H	0.664	1.00
356_K	411_I	0.661	1.00
209_W	277_P	0.661	1.00
24_L	145_L	0.658	1.00
392_T	395_Q	0.657	1.00
341_D	346_S	0.656	1.00
345_I	381_P	0.653	1.00
333_W	336_N	0.653	1.00
20_K	146_F	0.652	1.00
143_A	193_P	0.649	1.00
219_A	280_V	0.649	1.00
151_L	156_V	0.648	1.00
292_I	301_V	0.644	1.00
392_T	399_Y	0.643	1.00
106_V	132_R	0.639	1.00
272_S	287_E	0.639	1.00
82_S	179_S	0.637	1.00
97_S	160_G	0.636	1.00
270_T	285_V	0.634	1.00
347_V	419_W	0.634	1.00
272_S	283_R	0.634	1.00
204_Q	369_T	0.633	1.00
45_V	85_I	0.633	1.00
229_S	281_A	0.631	1.00
26_K	29_I	0.631	1.00
102_G	144_L	0.627	1.00
26_K	129_I	0.624	1.00
49_L	54_M	0.623	1.00
50_R	55_D	0.622	1.00
411_I	415_F	0.621	1.00
214_V	230_A	0.621	1.00
95_G	161_D	0.621	1.00
371_G	382_V	0.621	1.00
172_C	175_A	0.619	1.00
130_Y	399_Y	0.619	1.00
129_I	402_V	0.619	1.00
22_I	129_I	0.618	1.00
373_L	376_H	0.618	1.00
92_A	157_K	0.617	1.00
392_T	397_N	0.616	1.00
190_A	374_L	0.615	1.00
34_T	120_Y	0.614	1.00
22_I	406_I	0.614	1.00
192_I	382_V	0.613	1.00
306_E	328_W	0.612	1.00
115_W	119_P	0.607	1.00
25_L	402_V	0.606	1.00
228_V	321_R	0.604	1.00
410_K	413_A	0.603	1.00
25_L	142_T	0.601	1.00
356_K	407_E	0.600	1.00
121_Q	132_R	0.599	1.00
35_L	173_G	0.594	1.00
355_M	358_T	0.593	1.00
191_L	419_W	0.593	1.00
57_D	184_G	0.593	1.00
236_H	312_L	0.592	1.00
171_E	394_H	0.591	1.00
201_F	363_E	0.591	1.00
181_I	377_A	0.591	1.00
54_M	164_F	0.591	1.00
169_D	172_C	0.591	1.00
109_E	131_G	0.589	1.00
212_I	326_V	0.588	1.00
28_L	142_T	0.585	1.00
233_K	312_L	0.583	1.00
240_A	315_H	0.583	1.00
313_E	322_H	0.583	1.00
214_V	324_V	0.583	1.00
42_Q	58_V	0.583	1.00
232_E	239_T	0.582	1.00
90_T	94_G	0.581	1.00
38_E	169_D	0.580	1.00
40_N	47_E	0.580	1.00
402_V	406_I	0.580	1.00
237_V	308_W	0.576	1.00
98_L	419_W	0.575	1.00
378_G	382_V	0.574	1.00
192_I	371_G	0.573	1.00
101_N	165_Q	0.572	1.00
232_E	236_H	0.570	1.00
278_S	291_G	0.568	1.00
118_E	122_A	0.566	1.00
221_G	269_G	0.565	1.00
31_E	41_A	0.563	1.00
228_V	323_P	0.561	1.00
97_S	186_R	0.560	1.00
191_L	344_L	0.559	1.00
221_G	267_N	0.557	1.00
233_K	236_H	0.554	1.00
385_F	411_I	0.554	1.00
237_V	286_I	0.553	1.00
245_E	266_V	0.552	1.00
218_S	396_A	0.552	1.00
91_G	155_D	0.551	1.00
241_I	268_I	0.550	1.00
34_T	128_K	0.549	1.00
34_T	109_E	0.549	1.00
237_V	241_I	0.549	1.00
101_N	167_V	0.549	1.00
95_G	160_G	0.547	1.00
123_V	130_Y	0.547	1.00
223_T	365_S	0.547	1.00
385_F	389_E	0.544	1.00
212_I	288_G	0.543	1.00
303_L	310_K	0.541	1.00
305_L	326_V	0.540	1.00
177_T	374_L	0.535	1.00
288_G	305_L	0.534	1.00
309_L	326_V	0.534	1.00
115_W	120_Y	0.533	1.00
262_I	297_K	0.531	1.00
271_I	286_I	0.530	1.00
356_K	360_P	0.529	1.00
349_Q	359_E	0.529	1.00
204_Q	208_M	0.529	1.00
374_L	382_V	0.529	1.00
37_S	128_K	0.528	1.00
313_E	323_P	0.526	1.00
84_N	180_A	0.525	1.00
81_E	183_R	0.524	1.00
235_M	242_Q	0.524	1.00
32_K	118_E	0.524	1.00
165_Q	190_A	0.523	1.00
230_A	280_V	0.523	1.00
212_I	305_L	0.522	1.00
206_G	335_P	0.522	1.00
355_M	411_I	0.522	1.00
196_T	393_A	0.519	1.00
290_C	296_E	0.518	1.00
202_I	362_I	0.518	1.00
116_K	119_P	0.517	1.00
182_M	377_A	0.517	1.00
237_V	312_L	0.516	1.00
221_G	289_R	0.516	1.00
389_E	404_A	0.515	1.00
38_E	42_Q	0.515	1.00
342_H	381_P	0.515	1.00
52_F	153_A	0.515	1.00
28_L	45_V	0.514	1.00
406_I	409_A	0.511	1.00
21_A	25_L	0.511	1.00
200_L	349_Q	0.511	1.00
119_P	123_V	0.511	1.00
165_Q	374_L	0.509	1.00
204_Q	384_V	0.509	1.00
86_V	165_Q	0.509	1.00
351_A	411_I	0.508	1.00
352_Y	356_K	0.508	1.00
205_Q	265_P	0.507	1.00
24_L	52_F	0.507	1.00
96_R	189_G	0.506	1.00
229_S	247_V	0.506	1.00
393_A	398_E	0.505	1.00
160_G	188_D	0.504	1.00
57_D	86_V	0.503	1.00
201_F	208_M	0.503	1.00
274_G	284_V	0.502	1.00
227_G	280_V	0.502	1.00
103_H	136_D	0.501	1.00
298_P	332_Q	0.500	1.00
181_I	373_L	0.500	1.00
104_I	168_V	0.500	1.00
328_W	332_Q	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3pfoA	2	0.9702	100	0.243	Contact Map
3iszA	2	0.8257	100	0.318	Contact Map
4pqaA	2	0.8349	100	0.318	Contact Map
1cg2A	4	0.8601	100	0.326	Contact Map
3rzaA	2	0.8349	100	0.327	Contact Map
2pokA	2	0.9037	100	0.331	Contact Map
4mmoA	2	0.8624	100	0.332	Contact Map
2zogA	2	0.9266	100	0.332	Contact Map
4g1pA	2	0.9427	100	0.335	Contact Map
3dljA	2	0.922	100	0.335	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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