GREMLIN Database
RL31B - 50S ribosomal protein L31 type B
UniProt: O34967 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 82 (79)
Sequences: 985 (364)
Seq/√Len: 41.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
36_E42_T4.3081.00
13_I35_A4.1651.00
29_K46_I2.9521.00
33_E47_K2.7671.00
31_S46_I2.6391.00
10_H31_S2.5681.00
10_H30_T2.1810.99
21_Y53_D2.0290.99
15_Q22_R2.0260.99
24_L37_W1.9200.99
19_S53_D1.7890.98
23_F52_S1.7710.98
11_K26_T1.7550.98
11_K41_N1.7390.97
37_W41_N1.7060.97
68_G72_E1.6950.97
13_I37_W1.6790.97
17_V47_K1.5830.95
22_R37_W1.5400.95
22_R35_A1.5220.94
34_T42_T1.5090.94
10_H29_K1.4650.93
15_Q45_V1.4270.92
15_Q47_K1.1950.83
58_Y63_K1.1810.83
48_V51_S1.1770.82
76_K79_N1.1690.82
63_K68_G1.0820.77
19_S47_K1.0660.76
15_Q19_S0.9960.70
49_E58_Y0.9890.70
19_S51_S0.9820.69
61_R72_E0.9810.69
15_Q20_G0.9680.68
66_E75_K0.9590.67
15_Q35_A0.9390.66
13_I22_R0.9300.65
66_E73_Q0.9010.63
21_Y38_E0.8940.62
50_V62_Q0.8910.62
18_N54_T0.8830.61
24_L43_Y0.8610.59
19_S54_T0.8600.59
37_W43_Y0.8540.58
31_S45_V0.8480.58
50_V71_V0.8260.56
21_Y25_S0.8250.56
30_T46_I0.8210.55
35_A45_V0.8140.55
71_V75_K0.8140.55
21_Y37_W0.8050.54
26_T68_G0.8000.53
20_G53_D0.7930.53
67_K71_V0.7800.52
2_K73_Q0.7660.50
24_L35_A0.7620.50
66_E71_V0.7570.49
14_F52_S0.7550.49
62_Q76_K0.7490.49
64_F67_K0.7490.49
11_K24_L0.7450.48
75_K79_N0.7430.48
20_G70_R0.7380.48
18_N68_G0.7370.48
4_G30_T0.7350.47
17_V78_Y0.7220.46
20_G48_V0.7170.46
8_K34_T0.7130.45
4_G8_K0.7100.45
48_V75_K0.7080.45
70_R73_Q0.7000.44
72_E76_K0.7000.44
20_G38_E0.6980.44
38_E75_K0.6910.43
8_K30_T0.6860.43
64_F76_K0.6780.42
3_E62_Q0.6710.42
32_N73_Q0.6710.42
9_N44_P0.6680.41
66_E72_E0.6670.41
2_K6_H0.6620.41
28_T46_I0.6510.40
57_F71_V0.6480.39
1_M6_H0.6430.39
33_E75_K0.6360.38
3_E18_N0.6270.38
69_G74_F0.6260.38
19_S22_R0.6180.37
48_V78_Y0.6170.37
33_E45_V0.6120.36
67_K70_R0.6030.36
4_G61_R0.5990.35
67_K73_Q0.5960.35
11_K79_N0.5960.35
24_L70_R0.5940.35
36_E39_D0.5910.35
17_V58_Y0.5810.34
57_F66_E0.5800.34
66_E78_Y0.5750.33
66_E70_R0.5630.32
14_F77_R0.5550.32
56_P69_G0.5550.32
67_K76_K0.5540.32
49_E54_T0.5530.31
47_K72_E0.5480.31
64_F71_V0.5450.31
13_I78_Y0.5400.30
38_E77_R0.5360.30
21_Y52_S0.5260.29
70_R77_R0.5250.29
4_G25_S0.5230.29
64_F77_R0.5220.29
1_M7_P0.5140.28
14_F54_T0.5100.28
69_G78_Y0.5080.28
2_K5_I0.5060.28
18_N73_Q0.5040.28
36_E48_V0.5000.27
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3f1f4 1 0.3659 100 0.354 Contact Map
1nkwY 1 0.8171 100 0.359 Contact Map
4rb64 1 0.8171 100 0.361 Contact Map
1vs6Z 1 0.8293 100 0.362 Contact Map
3bbo1 1 0.8171 99.9 0.37 Contact Map
1vw4V 1 0.5854 99.8 0.507 Contact Map
4dapA 1 0.5488 6.7 0.942 Contact Map
2k89A 1 0.622 6.7 0.942 Contact Map
2ketA 1 0.1707 6.2 0.943 Contact Map
5aj3U 1 0.3537 5.1 0.945 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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