GREMLIN Database
LTAS2 - Lipoteichoic acid synthase 2
UniProt: O34952 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 649 (525)
Sequences: 3486 (2884)
Seq/√Len: 125.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
272_F449_E6.8921.00
333_K362_D6.6341.00
286_D518_H6.5341.00
532_H547_D4.9541.00
396_E458_D4.4851.00
248_I466_I4.2721.00
272_F275_K4.2391.00
250_V468_M4.1781.00
247_V534_L3.9021.00
521_A548_I3.9001.00
245_K463_K3.5061.00
247_V332_L3.4901.00
456_K461_Y3.4341.00
252_L255_L3.3841.00
248_I464_S3.2421.00
246_N464_S3.1511.00
281_E456_K3.1301.00
332_L534_L3.0921.00
461_Y508_H2.7861.00
246_N402_F2.7021.00
288_F521_A2.6731.00
449_E453_N2.5761.00
42_K46_F2.5591.00
453_N457_K2.4861.00
392_M454_D2.4561.00
465_I507_I2.4481.00
338_T400_Q2.4161.00
24_T28_Y2.3241.00
86_N96_F2.2971.00
366_D369_Y2.2921.00
450_Q453_N2.2431.00
455_L466_I2.2191.00
509_A512_V2.1571.00
46_F52_S2.1261.00
168_L173_S2.1251.00
505_L526_V2.1241.00
169_A173_S2.0931.00
249_Y403_Y2.0691.00
24_T27_G2.0641.00
452_F466_I2.0481.00
307_S528_P2.0411.00
402_F460_L1.9981.00
275_K449_E1.9731.00
261_D270_T1.9601.00
168_L172_E1.9431.00
55_F59_F1.9411.00
198_T201_D1.9401.00
168_L171_A1.9331.00
197_F201_D1.9331.00
286_D516_K1.9171.00
261_D274_N1.8981.00
470_G503_V1.8801.00
461_Y466_I1.8781.00
169_A172_E1.8781.00
252_L444_L1.8671.00
453_N456_K1.8561.00
270_T274_N1.8551.00
529_T549_L1.8481.00
388_F408_T1.8401.00
342_F394_L1.8111.00
411_N441_A1.8071.00
151_K154_R1.8041.00
249_Y467_V1.8001.00
268_E274_N1.8001.00
462_D511_G1.7941.00
164_F168_L1.7861.00
454_D457_K1.7841.00
46_F49_P1.7621.00
394_L397_S1.7431.00
276_L448_I1.7301.00
283_F549_L1.7261.00
259_I441_A1.6981.00
454_D458_D1.6891.00
272_F452_F1.6821.00
347_Q366_D1.6601.00
288_F505_L1.6561.00
273_L448_I1.6471.00
412_H471_D1.6441.00
557_I560_R1.6371.00
245_K465_I1.6351.00
306_N327_S1.6251.00
297_T407_I1.6191.00
297_T300_A1.6081.00
341_T356_Y1.6031.00
251_S301_E1.5971.00
21_W24_T1.5871.00
446_Q450_Q1.5821.00
23_K26_V1.5801.00
465_I530_I1.5761.00
341_T407_I1.5721.00
391_S406_F1.5691.00
45_L49_P1.5561.00
467_V507_I1.5541.00
171_A174_D1.5531.00
35_G39_T1.5521.00
448_I468_M1.5491.00
135_I139_I1.5391.00
255_L259_I1.5391.00
250_V388_F1.5371.00
554_R557_I1.5271.00
331_I531_L1.5261.00
556_V559_F1.5201.00
238_Y549_L1.5111.00
252_L468_M1.5101.00
252_L448_I1.5071.00
255_L444_L1.5071.00
165_L169_A1.5061.00
418_D443_Y1.5001.00
556_V560_R1.4921.00
314_G318_V1.4901.00
167_N171_A1.4901.00
91_R124_D1.4851.00
261_D278_H1.4691.00
385_K450_Q1.4651.00
389_K450_Q1.4641.00
390_E393_P1.4641.00
289_F502_R1.4631.00
38_N42_K1.4601.00
361_I405_K1.4511.00
282_T508_H1.4381.00
469_Y526_V1.4251.00
340_A404_T1.4221.00
347_Q353_N1.4211.00
251_S304_M1.4111.00
418_D421_D1.4101.00
392_M458_D1.4061.00
275_K281_E1.3971.00
277_A284_Y1.3891.00
49_P52_S1.3881.00
190_K195_Y1.3741.00
250_V448_I1.3731.00
108_N111_Q1.3621.00
385_K443_Y1.3591.00
39_T42_K1.3571.00
177_E181_R1.3531.00
219_D222_E1.3521.00
212_R215_A1.3471.00
447_S450_Q1.3421.00
283_F515_E1.3371.00
261_D268_E1.3201.00
42_K49_P1.3111.00
248_I402_F1.3061.00
24_T29_V1.2981.00
256_Q473_Y1.2961.00
450_Q454_D1.2951.00
23_K27_G1.2931.00
342_F404_T1.2921.00
467_V530_I1.2861.00
201_D204_Q1.2831.00
452_F468_M1.2691.00
452_F456_K1.2681.00
387_F406_F1.2681.00
442_H446_Q1.2611.00
46_F57_L1.2571.00
295_G299_D1.2561.00
388_F451_F1.2541.00
391_S395_L1.2511.00
385_K446_Q1.2461.00
388_F392_M1.2421.00
469_Y523_D1.2411.00
24_T31_N1.2391.00
503_V523_D1.2371.00
247_V465_I1.2361.00
54_L58_G1.2340.99
45_L59_F1.2330.99
271_P445_D1.2220.99
170_V174_D1.2210.99
336_N401_P1.2200.99
455_L459_G1.2160.99
394_L398_L1.2120.99
251_S405_K1.1990.99
353_N357_K1.1980.99
45_L48_N1.1970.99
291_Q303_M1.1950.99
338_T363_K1.1950.99
283_F517_V1.1920.99
160_S164_F1.1920.99
465_I509_A1.1910.99
251_S469_Y1.1870.99
352_R356_Y1.1870.99
304_M469_Y1.1840.99
23_K31_N1.1800.99
337_Y401_P1.1770.99
159_S163_V1.1730.99
35_G38_N1.1710.99
199_I202_A1.1670.99
48_N52_S1.1640.99
297_T301_E1.1590.99
243_E463_K1.1590.99
270_T273_L1.1550.99
525_D545_G1.1550.99
545_G548_I1.1540.99
528_P545_G1.1530.99
291_Q522_G1.1480.99
39_T49_P1.1440.99
276_L468_M1.1390.99
224_E228_K1.1360.99
203_V207_K1.1360.99
343_H352_R1.1350.99
282_T506_F1.1310.99
315_S318_V1.1290.99
351_N354_E1.1270.99
555_E560_R1.1270.99
154_R158_A1.1260.99
255_L273_L1.1250.99
455_L460_L1.1200.99
267_K438_F1.1190.99
295_G298_S1.1150.99
272_F453_N1.1140.99
312_A316_V1.1110.99
444_L447_S1.1100.99
396_E454_D1.1090.99
247_V467_V1.0990.99
257_S502_R1.0960.99
275_K278_H1.0950.99
132_I136_I1.0840.99
356_Y364_F1.0840.99
220_V223_V1.0820.99
161_I164_F1.0800.99
166_I170_V1.0790.99
553_H556_V1.0770.99
49_P59_F1.0770.99
199_I203_V1.0760.99
284_Y516_K1.0750.99
199_I206_I1.0730.99
198_T205_N1.0710.99
329_P361_I1.0710.99
259_I438_F1.0660.99
246_N401_P1.0650.99
47_V51_S1.0630.98
27_G30_L1.0580.98
426_A433_V1.0560.98
287_N520_Y1.0530.98
44_L49_P1.0490.98
304_M526_V1.0490.98
220_V224_E1.0480.98
219_D223_V1.0480.98
197_F203_V1.0460.98
221_T225_N1.0460.98
23_K28_Y1.0430.98
167_N172_E1.0400.98
35_G49_P1.0390.98
253_E408_T1.0340.98
419_E422_T1.0310.98
223_V226_Y1.0300.98
16_A20_L1.0300.98
338_T398_L1.0280.98
44_L47_V1.0260.98
340_A398_L1.0250.98
277_A506_F1.0230.98
86_N411_N1.0210.98
38_N41_Q1.0190.98
198_T206_I1.0180.98
424_F442_H1.0130.98
255_L441_A1.0110.98
249_Y304_M1.0100.98
163_V167_N1.0050.98
49_P53_S1.0040.98
198_T202_A1.0040.98
547_D550_S1.0030.98
177_E182_S1.0010.98
391_S404_T0.9950.98
252_L388_F0.9940.98
388_F444_L0.9940.98
342_F365_F0.9920.98
314_G317_F0.9890.98
49_P64_K0.9870.98
306_N355_M0.9820.97
218_S227_M0.9770.97
201_D208_S0.9760.97
386_P390_E0.9740.97
49_P60_G0.9720.97
248_I455_L0.9680.97
222_E225_N0.9660.97
77_F81_F0.9650.97
335_K536_V0.9640.97
86_N97_I0.9590.97
531_L536_V0.9580.97
349_F352_R0.9580.97
218_S222_E0.9550.97
197_F205_N0.9530.97
303_M523_D0.9530.97
468_M506_F0.9480.97
338_T362_D0.9460.97
170_V173_S0.9450.97
164_F171_A0.9430.97
85_A97_I0.9420.97
257_S284_Y0.9380.97
147_T150_K0.9370.97
332_L531_L0.9350.97
192_L195_Y0.9340.97
301_E352_R0.9340.97
20_L23_K0.9320.97
316_V320_K0.9290.96
316_V319_N0.9290.96
169_A174_D0.9270.96
192_L196_N0.9230.96
46_F55_F0.9190.96
390_E394_L0.9180.96
411_N444_L0.9180.96
164_F172_E0.9170.96
340_A363_K0.9170.96
45_L51_S0.9160.96
276_L452_F0.9160.96
19_L23_K0.9070.96
417_M424_F0.9050.96
52_S57_L0.9050.96
411_N440_S0.9040.96
462_D510_A0.9040.96
125_A129_I0.9030.96
146_E149_S0.9010.96
168_L174_D0.9010.96
197_F204_Q0.9000.96
253_E412_H0.8970.96
253_E471_D0.8950.96
201_D206_I0.8930.96
156_I160_S0.8930.96
392_M396_E0.8900.95
45_L57_L0.8880.95
255_L468_M0.8840.95
383_K386_P0.8820.95
384_D388_F0.8810.95
393_P454_D0.8800.95
317_F320_K0.8800.95
89_Y299_D0.8740.95
455_L461_Y0.8720.95
49_P55_F0.8700.95
421_D425_P0.8660.95
389_K454_D0.8660.95
273_L284_Y0.8660.95
193_G196_N0.8650.95
136_I139_I0.8620.95
199_I205_N0.8610.95
256_Q437_Y0.8600.95
155_I173_S0.8590.95
150_K153_F0.8570.94
166_I173_S0.8550.94
417_M439_Q0.8530.94
311_L319_N0.8500.94
448_I452_F0.8480.94
19_L24_T0.8470.94
381_G384_D0.8450.94
417_M422_T0.8440.94
128_F131_T0.8430.94
328_V531_L0.8420.94
156_I171_A0.8420.94
200_Y205_N0.8410.94
196_N199_I0.8410.94
149_S152_S0.8410.94
181_R184_D0.8410.94
263_K284_Y0.8390.94
46_F59_F0.8380.94
240_G244_G0.8370.94
328_V527_A0.8360.94
43_I46_F0.8340.94
168_L175_R0.8330.94
125_A128_F0.8330.94
249_Y328_V0.8320.94
156_I167_N0.8310.94
48_N51_S0.8310.94
410_S440_S0.8290.93
555_E559_F0.8290.93
71_A75_I0.8290.93
184_D190_K0.8290.93
177_E183_F0.8260.93
244_G401_P0.8240.93
229_A232_D0.8230.93
344_G380_Y0.8230.93
245_K337_Y0.8220.93
198_T208_S0.8220.93
137_L142_N0.8190.93
28_Y31_N0.8190.93
38_N43_I0.8180.93
395_L404_T0.8180.93
248_I395_L0.8160.93
313_Q316_V0.8130.93
339_S362_D0.8130.93
204_Q208_S0.8130.93
344_G381_G0.8130.93
28_Y32_F0.8110.93
55_F162_L0.8080.93
198_T204_Q0.8080.93
67_L70_T0.8080.93
345_N349_F0.8080.93
339_S407_I0.8060.92
298_S301_E0.8040.92
554_R559_F0.8040.92
35_G42_K0.8030.92
136_I140_K0.8010.92
527_A531_L0.8000.92
202_A206_I0.7990.92
46_F54_L0.7980.92
309_Y544_S0.7980.92
191_Y196_N0.7970.92
354_E357_K0.7960.92
146_E150_K0.7930.92
287_N502_R0.7930.92
24_T33_N0.7930.92
201_D205_N0.7910.92
51_S57_L0.7910.92
161_I165_L0.7900.92
244_G335_K0.7890.92
242_A465_I0.7870.92
551_K554_R0.7850.91
350_W355_M0.7830.91
273_L506_F0.7830.91
219_D224_E0.7820.91
416_G436_N0.7820.91
444_L448_I0.7810.91
215_A219_D0.7810.91
296_K299_D0.7790.91
70_T74_V0.7780.91
112_L115_S0.7750.91
554_R558_P0.7730.91
205_N209_N0.7710.91
89_Y93_F0.7690.91
215_A220_V0.7600.90
553_H558_P0.7600.90
54_L160_S0.7580.90
201_D207_K0.7570.90
220_V226_Y0.7560.90
305_E403_Y0.7560.90
128_F132_I0.7550.90
22_I155_I0.7530.90
46_F51_S0.7510.90
311_L315_S0.7500.89
140_K144_P0.7470.89
200_Y204_Q0.7460.89
410_S443_Y0.7440.89
276_L506_F0.7440.89
246_N462_D0.7440.89
216_D219_D0.7430.89
303_M408_T0.7430.89
400_Q463_K0.7430.89
17_V27_G0.7420.89
151_K155_I0.7410.89
555_E558_P0.7400.89
393_P397_S0.7390.89
133_I137_L0.7390.89
19_L26_V0.7380.89
164_F167_N0.7380.89
352_R407_I0.7380.89
270_T445_D0.7360.89
406_F451_F0.7360.89
141_V153_F0.7340.88
176_P181_R0.7340.88
154_R166_I0.7310.88
248_I451_F0.7310.88
277_A282_T0.7300.88
532_H550_S0.7300.88
302_F316_V0.7300.88
39_T46_F0.7300.88
166_I171_A0.7290.88
349_F356_Y0.7280.88
370_Y387_F0.7270.88
437_Y441_A0.7250.88
13_F20_L0.7240.88
505_L548_I0.7210.88
312_A315_S0.7190.87
176_P182_S0.7190.87
227_M231_Y0.7180.87
345_N410_S0.7180.87
153_F156_I0.7170.87
294_Q300_A0.7160.87
26_V30_L0.7150.87
340_A394_L0.7140.87
449_E452_F0.7130.87
365_F394_L0.7130.87
165_L172_E0.7130.87
21_W25_Y0.7120.87
92_F415_F0.7120.87
38_N45_L0.7120.87
176_P183_F0.7100.87
175_R183_F0.7080.87
407_I470_G0.7050.86
37_D41_Q0.7050.86
348_T353_N0.7040.86
300_A523_D0.7040.86
172_E175_R0.7000.86
240_G245_K0.6970.86
256_Q476_S0.6940.86
381_G414_P0.6940.86
272_F448_I0.6930.85
412_H472_H0.6920.85
415_F474_G0.6910.85
331_I334_S0.6910.85
205_N208_S0.6900.85
285_F505_L0.6900.85
197_F202_A0.6900.85
185_R188_L0.6890.85
295_G300_A0.6880.85
262_Y269_V0.6870.85
284_Y506_F0.6860.85
210_S214_L0.6850.85
340_A402_F0.6840.85
260_I270_T0.6840.85
46_F56_F0.6820.85
15_I20_L0.6810.84
301_E350_W0.6810.84
217_S225_N0.6810.84
43_I47_V0.6800.84
13_F415_F0.6770.84
332_L465_I0.6760.84
44_L59_F0.6760.84
435_D439_Q0.6750.84
44_L51_S0.6740.84
337_Y465_I0.6730.84
288_F526_V0.6720.84
285_F289_F0.6720.84
27_G31_N0.6710.84
131_T139_I0.6690.83
255_L270_T0.6690.83
437_Y440_S0.6690.83
499_Q502_R0.6680.83
53_S59_F0.6680.83
294_Q297_T0.6650.83
202_A208_S0.6650.83
290_H473_Y0.6650.83
329_P403_Y0.6640.83
163_V166_I0.6630.83
184_D188_L0.6620.83
355_M359_E0.6610.83
147_T152_S0.6610.83
247_V403_Y0.6590.82
13_F17_V0.6580.82
39_T43_I0.6560.82
163_V170_V0.6550.82
381_G409_L0.6550.82
199_I209_N0.6540.82
47_V54_L0.6540.82
420_G423_D0.6530.82
198_T207_K0.6530.82
422_T426_A0.6520.82
198_T203_V0.6520.82
186_N190_K0.6520.82
339_S403_Y0.6490.82
122_P126_F0.6490.82
20_L24_T0.6490.82
167_N170_V0.6490.82
360_G530_I0.6480.81
473_Y476_S0.6470.81
116_A347_Q0.6460.81
395_L451_F0.6450.81
57_L64_K0.6440.81
408_T451_F0.6440.81
44_L52_S0.6440.81
131_T135_I0.6420.81
418_D422_T0.6410.81
45_L54_L0.6400.81
266_G274_N0.6390.81
264_I274_N0.6380.80
72_I75_I0.6380.80
296_K300_A0.6360.80
175_R181_R0.6360.80
53_S58_G0.6350.80
298_S350_W0.6310.80
343_H409_L0.6310.80
294_Q299_D0.6300.80
63_F71_A0.6290.79
89_Y98_T0.6290.79
253_E384_D0.6280.79
475_I500_L0.6280.79
156_I174_D0.6280.79
50_L57_L0.6270.79
171_A175_R0.6260.79
118_S413_F0.6250.79
251_S407_I0.6250.79
15_I18_V0.6250.79
133_I139_I0.6240.79
90_Y308_L0.6230.79
162_L166_I0.6210.79
25_Y29_V0.6190.78
361_I407_I0.6180.78
236_N239_F0.6180.78
47_V59_F0.6170.78
452_F461_Y0.6170.78
273_L441_A0.6160.78
42_K52_S0.6160.78
25_Y32_F0.6160.78
178_L181_R0.6150.78
243_E457_K0.6140.78
40_I44_L0.6130.78
138_A142_N0.6120.78
271_P276_L0.6100.77
51_S61_L0.6090.77
352_R364_F0.6090.77
23_K29_V0.6090.77
54_L57_L0.6080.77
260_I506_F0.6060.77
199_I204_Q0.6050.77
438_F470_G0.6040.77
197_F208_S0.6040.77
241_K244_G0.6040.77
370_Y390_E0.6040.77
212_R216_D0.6030.77
421_D424_F0.6010.76
302_F306_N0.6010.76
446_Q449_E0.6000.76
253_E470_G0.6000.76
203_V208_S0.5990.76
165_L168_L0.5990.76
47_V60_G0.5980.76
314_G320_K0.5970.76
269_V438_F0.5960.76
224_E227_M0.5960.76
187_Y190_K0.5950.76
48_N60_G0.5950.76
343_H350_W0.5950.76
239_F532_H0.5950.76
44_L48_N0.5940.76
42_K45_L0.5940.76
124_D128_F0.5930.75
213_A216_D0.5930.75
179_L183_F0.5930.75
381_G451_F0.5930.75
424_F439_Q0.5920.75
158_A169_A0.5920.75
47_V55_F0.5920.75
466_I508_H0.5920.75
211_Q216_D0.5910.75
165_L173_S0.5910.75
149_S169_A0.5910.75
451_F466_I0.5910.75
17_V24_T0.5900.75
288_F291_Q0.5890.75
344_G382_M0.5890.75
305_E405_K0.5880.75
81_F85_A0.5880.75
513_K534_L0.5870.75
57_L61_L0.5870.75
46_F60_G0.5860.75
29_V32_F0.5840.74
386_P389_K0.5840.74
295_G301_E0.5830.74
195_Y202_A0.5820.74
387_F391_S0.5810.74
156_I173_S0.5810.74
45_L52_S0.5810.74
494_D498_A0.5790.74
179_L182_S0.5790.74
408_T444_L0.5780.74
221_T224_E0.5780.74
15_I26_V0.5770.73
273_L282_T0.5770.73
208_S214_L0.5760.73
278_H281_E0.5750.73
285_F288_F0.5740.73
149_S160_S0.5740.73
362_D389_K0.5740.73
553_H559_F0.5730.73
134_L138_A0.5730.73
333_K339_S0.5730.73
23_K30_L0.5730.73
516_K519_K0.5720.73
199_I208_S0.5700.73
175_R179_L0.5680.72
422_T425_P0.5680.72
312_A319_N0.5660.72
41_Q48_N0.5640.72
350_W356_Y0.5640.72
342_F387_F0.5640.72
16_A19_L0.5640.72
344_G387_F0.5620.71
494_D518_H0.5610.71
245_K511_G0.5590.71
185_R195_Y0.5580.71
326_Q334_S0.5580.71
159_S162_L0.5570.71
184_D191_Y0.5570.71
73_I76_H0.5560.71
35_G41_Q0.5540.70
13_F19_L0.5540.70
346_T367_S0.5540.70
375_E389_K0.5540.70
444_L523_D0.5540.70
178_L182_S0.5530.70
24_T30_L0.5520.70
206_I210_S0.5520.70
19_L29_V0.5500.70
156_I168_L0.5500.70
340_A365_F0.5500.70
126_F129_I0.5500.70
157_F168_L0.5480.70
167_N174_D0.5470.69
332_L403_Y0.5470.69
218_S221_T0.5470.69
527_A543_M0.5470.69
315_S319_N0.5460.69
200_Y203_V0.5450.69
165_L174_D0.5440.69
385_K421_D0.5440.69
141_V149_S0.5440.69
14_L24_T0.5430.69
17_V23_K0.5420.69
269_V274_N0.5410.69
159_S170_V0.5410.69
145_A148_S0.5410.69
498_A501_Q0.5400.68
160_S167_N0.5400.68
285_F547_D0.5400.68
249_Y526_V0.5390.68
231_Y234_P0.5390.68
203_V206_I0.5390.68
239_F242_A0.5380.68
301_E343_H0.5380.68
193_G208_S0.5370.68
552_E555_E0.5370.68
98_T411_N0.5370.68
217_S221_T0.5370.68
46_F50_L0.5350.68
261_D264_I0.5340.68
461_Y464_S0.5340.68
197_F200_Y0.5340.68
219_D333_K0.5330.67
39_T44_L0.5320.67
44_L56_F0.5320.67
157_F170_V0.5310.67
343_H410_S0.5300.67
459_G462_D0.5300.67
133_I136_I0.5280.67
245_K401_P0.5280.67
255_L260_I0.5280.67
223_V227_M0.5280.67
42_K55_F0.5280.67
311_L316_V0.5270.67
277_A286_D0.5270.67
51_S55_F0.5270.67
437_Y470_G0.5270.67
155_I171_A0.5260.66
48_N61_L0.5260.66
155_I161_I0.5260.66
72_I76_H0.5260.66
281_E513_K0.5260.66
59_F64_K0.5260.66
165_L170_V0.5260.66
524_V528_P0.5250.66
245_K464_S0.5250.66
47_V57_L0.5250.66
246_N465_I0.5240.66
43_I48_N0.5240.66
344_G409_L0.5230.66
263_K274_N0.5230.66
204_Q207_K0.5220.66
46_F53_S0.5220.66
496_D500_L0.5220.66
379_N409_L0.5220.66
382_M390_E0.5210.66
202_A207_K0.5200.66
262_Y273_L0.5190.65
437_Y474_G0.5190.65
34_L37_D0.5190.65
89_Y95_D0.5190.65
351_N356_Y0.5190.65
332_L335_K0.5180.65
378_K383_K0.5170.65
154_R167_N0.5160.65
275_K457_K0.5160.65
437_Y473_Y0.5160.65
254_S381_G0.5160.65
164_F169_A0.5140.65
125_A403_Y0.5140.65
274_N277_A0.5140.65
378_K410_S0.5120.64
298_S310_P0.5120.64
217_S222_E0.5110.64
269_V449_E0.5110.64
505_L521_A0.5110.64
387_F409_L0.5100.64
46_F61_L0.5100.64
285_F290_H0.5100.64
345_N415_F0.5090.64
335_K531_L0.5090.64
290_H294_Q0.5080.64
551_K557_I0.5070.64
254_S472_H0.5060.63
48_N58_G0.5060.63
254_S415_F0.5050.63
247_V530_I0.5050.63
86_N89_Y0.5050.63
395_L460_L0.5040.63
158_A173_S0.5030.63
295_G350_W0.5030.63
187_Y194_T0.5020.63
240_G243_E0.5020.63
247_V255_L0.5020.63
89_Y298_S0.5010.63
86_N198_T0.5010.63
149_S153_F0.5000.63
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2w8dA 1 0.641 100 0.418 Contact Map
2w5qA 1 0.641 100 0.436 Contact Map
4uorA 3 0.6379 100 0.45 Contact Map
4uopA 2 0.6009 100 0.486 Contact Map
3lxqA 1 0.5932 100 0.529 Contact Map
4upiA 2 0.6009 100 0.53 Contact Map
3ed4A 3 0.5963 100 0.531 Contact Map
4uplA 2 0.6055 100 0.532 Contact Map
4uphA 2 0.5763 100 0.533 Contact Map
1fsuA 1 0.5809 100 0.535 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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