LTAS2 - BACSU - GREMLIN Contacts

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LTAS2 - Lipoteichoic acid synthase 2

UniProt:	O34952	Sequences: MKTFIKERGLAFFLIAVVLLWIKTYVGYVLNFNLGIDNTIQKILLFVNPLSSSLFFLGFGLLFKKKLQQTAIIVIHFLMSFLLYANIVYYRFFNDFITIPVIMQAKTNGGQLGDSAFSLMRPTDAFYFIDTIILIILAIKVNKPAETSSKKSFRIIFASSILVFLINLAVAESDRPELLTRSFDRNYLVKYLGTYNFTIYDAVQNIKSNSQRALADSSDVTEVENYMKANYDVPNNVYFGKAEGKNVIYVSLESLQSFIIDYKIDGKEVTPFLNKLAHDNETFYFDNFFHQTGQGKTSDAEFMMENSLYPLAQGSVFVNKAQNTLQSVPAILKSKNYTSATFHGNTQTFWNRNEMYKAEGIDKFFDSAYYDMNEENTKNYGMKDKPFFKESMPLLESLPQPFYTKFITLSNHFPFGMDEGDTDFPAGDFGDSVVDNYFQSAHYLDQSIEQFFNDLKKDGLYDKSIIVMYGDHYGISENHNKAMAKVLGKDEITDYDNAQLQRVPLFIHAAGVKGEKVHKYAGDVDVAPTILHLLGVDTKDYLMSGSDILSKEHREVIPFRNGDFISPKYTKISGKYYDTKTGKELDESEVDKSEDSLVKKELEMSDKIINGDLLRFYEPKGFKKVNPSDYDYTKHDEDSSETSKDNEDK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	649 (525)
Sequences:	3486 (2884)
Seq/√Len:	125.9

ECOLI - YEJM EPTC EPTA YHBX EPTB OPGE OPGB YIDJ
BACSU - LTAS2 YQGS LTAS1 YVGJ

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
272_F	449_E	6.892	1.00
333_K	362_D	6.634	1.00
286_D	518_H	6.534	1.00
532_H	547_D	4.954	1.00
396_E	458_D	4.485	1.00
248_I	466_I	4.272	1.00
272_F	275_K	4.239	1.00
250_V	468_M	4.178	1.00
247_V	534_L	3.902	1.00
521_A	548_I	3.900	1.00
245_K	463_K	3.506	1.00
247_V	332_L	3.490	1.00
456_K	461_Y	3.434	1.00
252_L	255_L	3.384	1.00
248_I	464_S	3.242	1.00
246_N	464_S	3.151	1.00
281_E	456_K	3.130	1.00
332_L	534_L	3.092	1.00
461_Y	508_H	2.786	1.00
246_N	402_F	2.702	1.00
288_F	521_A	2.673	1.00
449_E	453_N	2.576	1.00
42_K	46_F	2.559	1.00
453_N	457_K	2.486	1.00
392_M	454_D	2.456	1.00
465_I	507_I	2.448	1.00
338_T	400_Q	2.416	1.00
24_T	28_Y	2.324	1.00
86_N	96_F	2.297	1.00
366_D	369_Y	2.292	1.00
450_Q	453_N	2.243	1.00
455_L	466_I	2.219	1.00
509_A	512_V	2.157	1.00
46_F	52_S	2.126	1.00
168_L	173_S	2.125	1.00
505_L	526_V	2.124	1.00
169_A	173_S	2.093	1.00
249_Y	403_Y	2.069	1.00
24_T	27_G	2.064	1.00
452_F	466_I	2.048	1.00
307_S	528_P	2.041	1.00
402_F	460_L	1.998	1.00
275_K	449_E	1.973	1.00
261_D	270_T	1.960	1.00
168_L	172_E	1.943	1.00
55_F	59_F	1.941	1.00
198_T	201_D	1.940	1.00
168_L	171_A	1.933	1.00
197_F	201_D	1.933	1.00
286_D	516_K	1.917	1.00
261_D	274_N	1.898	1.00
470_G	503_V	1.880	1.00
461_Y	466_I	1.878	1.00
169_A	172_E	1.878	1.00
252_L	444_L	1.867	1.00
453_N	456_K	1.856	1.00
270_T	274_N	1.855	1.00
529_T	549_L	1.848	1.00
388_F	408_T	1.840	1.00
342_F	394_L	1.811	1.00
411_N	441_A	1.807	1.00
151_K	154_R	1.804	1.00
249_Y	467_V	1.800	1.00
268_E	274_N	1.800	1.00
462_D	511_G	1.794	1.00
164_F	168_L	1.786	1.00
454_D	457_K	1.784	1.00
46_F	49_P	1.762	1.00
394_L	397_S	1.743	1.00
276_L	448_I	1.730	1.00
283_F	549_L	1.726	1.00
259_I	441_A	1.698	1.00
454_D	458_D	1.689	1.00
272_F	452_F	1.682	1.00
347_Q	366_D	1.660	1.00
288_F	505_L	1.656	1.00
273_L	448_I	1.647	1.00
412_H	471_D	1.644	1.00
557_I	560_R	1.637	1.00
245_K	465_I	1.635	1.00
306_N	327_S	1.625	1.00
297_T	407_I	1.619	1.00
297_T	300_A	1.608	1.00
341_T	356_Y	1.603	1.00
251_S	301_E	1.597	1.00
21_W	24_T	1.587	1.00
446_Q	450_Q	1.582	1.00
23_K	26_V	1.580	1.00
465_I	530_I	1.576	1.00
341_T	407_I	1.572	1.00
391_S	406_F	1.569	1.00
45_L	49_P	1.556	1.00
467_V	507_I	1.554	1.00
171_A	174_D	1.553	1.00
35_G	39_T	1.552	1.00
448_I	468_M	1.549	1.00
135_I	139_I	1.539	1.00
255_L	259_I	1.539	1.00
250_V	388_F	1.537	1.00
554_R	557_I	1.527	1.00
331_I	531_L	1.526	1.00
556_V	559_F	1.520	1.00
238_Y	549_L	1.511	1.00
252_L	468_M	1.510	1.00
252_L	448_I	1.507	1.00
255_L	444_L	1.507	1.00
165_L	169_A	1.506	1.00
418_D	443_Y	1.500	1.00
556_V	560_R	1.492	1.00
314_G	318_V	1.490	1.00
167_N	171_A	1.490	1.00
91_R	124_D	1.485	1.00
261_D	278_H	1.469	1.00
385_K	450_Q	1.465	1.00
389_K	450_Q	1.464	1.00
390_E	393_P	1.464	1.00
289_F	502_R	1.463	1.00
38_N	42_K	1.460	1.00
361_I	405_K	1.451	1.00
282_T	508_H	1.438	1.00
469_Y	526_V	1.425	1.00
340_A	404_T	1.422	1.00
347_Q	353_N	1.421	1.00
251_S	304_M	1.411	1.00
418_D	421_D	1.410	1.00
392_M	458_D	1.406	1.00
275_K	281_E	1.397	1.00
277_A	284_Y	1.389	1.00
49_P	52_S	1.388	1.00
190_K	195_Y	1.374	1.00
250_V	448_I	1.373	1.00
108_N	111_Q	1.362	1.00
385_K	443_Y	1.359	1.00
39_T	42_K	1.357	1.00
177_E	181_R	1.353	1.00
219_D	222_E	1.352	1.00
212_R	215_A	1.347	1.00
447_S	450_Q	1.342	1.00
283_F	515_E	1.337	1.00
261_D	268_E	1.320	1.00
42_K	49_P	1.311	1.00
248_I	402_F	1.306	1.00
24_T	29_V	1.298	1.00
256_Q	473_Y	1.296	1.00
450_Q	454_D	1.295	1.00
23_K	27_G	1.293	1.00
342_F	404_T	1.292	1.00
467_V	530_I	1.286	1.00
201_D	204_Q	1.283	1.00
452_F	468_M	1.269	1.00
452_F	456_K	1.268	1.00
387_F	406_F	1.268	1.00
442_H	446_Q	1.261	1.00
46_F	57_L	1.257	1.00
295_G	299_D	1.256	1.00
388_F	451_F	1.254	1.00
391_S	395_L	1.251	1.00
385_K	446_Q	1.246	1.00
388_F	392_M	1.242	1.00
469_Y	523_D	1.241	1.00
24_T	31_N	1.239	1.00
503_V	523_D	1.237	1.00
247_V	465_I	1.236	1.00
54_L	58_G	1.234	0.99
45_L	59_F	1.233	0.99
271_P	445_D	1.222	0.99
170_V	174_D	1.221	0.99
336_N	401_P	1.220	0.99
455_L	459_G	1.216	0.99
394_L	398_L	1.212	0.99
251_S	405_K	1.199	0.99
353_N	357_K	1.198	0.99
45_L	48_N	1.197	0.99
291_Q	303_M	1.195	0.99
338_T	363_K	1.195	0.99
283_F	517_V	1.192	0.99
160_S	164_F	1.192	0.99
465_I	509_A	1.191	0.99
251_S	469_Y	1.187	0.99
352_R	356_Y	1.187	0.99
304_M	469_Y	1.184	0.99
23_K	31_N	1.180	0.99
337_Y	401_P	1.177	0.99
159_S	163_V	1.173	0.99
35_G	38_N	1.171	0.99
199_I	202_A	1.167	0.99
48_N	52_S	1.164	0.99
297_T	301_E	1.159	0.99
243_E	463_K	1.159	0.99
270_T	273_L	1.155	0.99
525_D	545_G	1.155	0.99
545_G	548_I	1.154	0.99
528_P	545_G	1.153	0.99
291_Q	522_G	1.148	0.99
39_T	49_P	1.144	0.99
276_L	468_M	1.139	0.99
224_E	228_K	1.136	0.99
203_V	207_K	1.136	0.99
343_H	352_R	1.135	0.99
282_T	506_F	1.131	0.99
315_S	318_V	1.129	0.99
351_N	354_E	1.127	0.99
555_E	560_R	1.127	0.99
154_R	158_A	1.126	0.99
255_L	273_L	1.125	0.99
455_L	460_L	1.120	0.99
267_K	438_F	1.119	0.99
295_G	298_S	1.115	0.99
272_F	453_N	1.114	0.99
312_A	316_V	1.111	0.99
444_L	447_S	1.110	0.99
396_E	454_D	1.109	0.99
247_V	467_V	1.099	0.99
257_S	502_R	1.096	0.99
275_K	278_H	1.095	0.99
132_I	136_I	1.084	0.99
356_Y	364_F	1.084	0.99
220_V	223_V	1.082	0.99
161_I	164_F	1.080	0.99
166_I	170_V	1.079	0.99
553_H	556_V	1.077	0.99
49_P	59_F	1.077	0.99
199_I	203_V	1.076	0.99
284_Y	516_K	1.075	0.99
199_I	206_I	1.073	0.99
198_T	205_N	1.071	0.99
329_P	361_I	1.071	0.99
259_I	438_F	1.066	0.99
246_N	401_P	1.065	0.99
47_V	51_S	1.063	0.98
27_G	30_L	1.058	0.98
426_A	433_V	1.056	0.98
287_N	520_Y	1.053	0.98
44_L	49_P	1.049	0.98
304_M	526_V	1.049	0.98
220_V	224_E	1.048	0.98
219_D	223_V	1.048	0.98
197_F	203_V	1.046	0.98
221_T	225_N	1.046	0.98
23_K	28_Y	1.043	0.98
167_N	172_E	1.040	0.98
35_G	49_P	1.039	0.98
253_E	408_T	1.034	0.98
419_E	422_T	1.031	0.98
223_V	226_Y	1.030	0.98
16_A	20_L	1.030	0.98
338_T	398_L	1.028	0.98
44_L	47_V	1.026	0.98
340_A	398_L	1.025	0.98
277_A	506_F	1.023	0.98
86_N	411_N	1.021	0.98
38_N	41_Q	1.019	0.98
198_T	206_I	1.018	0.98
424_F	442_H	1.013	0.98
255_L	441_A	1.011	0.98
249_Y	304_M	1.010	0.98
163_V	167_N	1.005	0.98
49_P	53_S	1.004	0.98
198_T	202_A	1.004	0.98
547_D	550_S	1.003	0.98
177_E	182_S	1.001	0.98
391_S	404_T	0.995	0.98
252_L	388_F	0.994	0.98
388_F	444_L	0.994	0.98
342_F	365_F	0.992	0.98
314_G	317_F	0.989	0.98
49_P	64_K	0.987	0.98
306_N	355_M	0.982	0.97
218_S	227_M	0.977	0.97
201_D	208_S	0.976	0.97
386_P	390_E	0.974	0.97
49_P	60_G	0.972	0.97
248_I	455_L	0.968	0.97
222_E	225_N	0.966	0.97
77_F	81_F	0.965	0.97
335_K	536_V	0.964	0.97
86_N	97_I	0.959	0.97
531_L	536_V	0.958	0.97
349_F	352_R	0.958	0.97
218_S	222_E	0.955	0.97
197_F	205_N	0.953	0.97
303_M	523_D	0.953	0.97
468_M	506_F	0.948	0.97
338_T	362_D	0.946	0.97
170_V	173_S	0.945	0.97
164_F	171_A	0.943	0.97
85_A	97_I	0.942	0.97
257_S	284_Y	0.938	0.97
147_T	150_K	0.937	0.97
332_L	531_L	0.935	0.97
192_L	195_Y	0.934	0.97
301_E	352_R	0.934	0.97
20_L	23_K	0.932	0.97
316_V	320_K	0.929	0.96
316_V	319_N	0.929	0.96
169_A	174_D	0.927	0.96
192_L	196_N	0.923	0.96
46_F	55_F	0.919	0.96
390_E	394_L	0.918	0.96
411_N	444_L	0.918	0.96
164_F	172_E	0.917	0.96
340_A	363_K	0.917	0.96
45_L	51_S	0.916	0.96
276_L	452_F	0.916	0.96
19_L	23_K	0.907	0.96
417_M	424_F	0.905	0.96
52_S	57_L	0.905	0.96
411_N	440_S	0.904	0.96
462_D	510_A	0.904	0.96
125_A	129_I	0.903	0.96
146_E	149_S	0.901	0.96
168_L	174_D	0.901	0.96
197_F	204_Q	0.900	0.96
253_E	412_H	0.897	0.96
253_E	471_D	0.895	0.96
201_D	206_I	0.893	0.96
156_I	160_S	0.893	0.96
392_M	396_E	0.890	0.95
45_L	57_L	0.888	0.95
255_L	468_M	0.884	0.95
383_K	386_P	0.882	0.95
384_D	388_F	0.881	0.95
393_P	454_D	0.880	0.95
317_F	320_K	0.880	0.95
89_Y	299_D	0.874	0.95
455_L	461_Y	0.872	0.95
49_P	55_F	0.870	0.95
421_D	425_P	0.866	0.95
389_K	454_D	0.866	0.95
273_L	284_Y	0.866	0.95
193_G	196_N	0.865	0.95
136_I	139_I	0.862	0.95
199_I	205_N	0.861	0.95
256_Q	437_Y	0.860	0.95
155_I	173_S	0.859	0.95
150_K	153_F	0.857	0.94
166_I	173_S	0.855	0.94
417_M	439_Q	0.853	0.94
311_L	319_N	0.850	0.94
448_I	452_F	0.848	0.94
19_L	24_T	0.847	0.94
381_G	384_D	0.845	0.94
417_M	422_T	0.844	0.94
128_F	131_T	0.843	0.94
328_V	531_L	0.842	0.94
156_I	171_A	0.842	0.94
200_Y	205_N	0.841	0.94
196_N	199_I	0.841	0.94
149_S	152_S	0.841	0.94
181_R	184_D	0.841	0.94
263_K	284_Y	0.839	0.94
46_F	59_F	0.838	0.94
240_G	244_G	0.837	0.94
328_V	527_A	0.836	0.94
43_I	46_F	0.834	0.94
168_L	175_R	0.833	0.94
125_A	128_F	0.833	0.94
249_Y	328_V	0.832	0.94
156_I	167_N	0.831	0.94
48_N	51_S	0.831	0.94
410_S	440_S	0.829	0.93
555_E	559_F	0.829	0.93
71_A	75_I	0.829	0.93
184_D	190_K	0.829	0.93
177_E	183_F	0.826	0.93
244_G	401_P	0.824	0.93
229_A	232_D	0.823	0.93
344_G	380_Y	0.823	0.93
245_K	337_Y	0.822	0.93
198_T	208_S	0.822	0.93
137_L	142_N	0.819	0.93
28_Y	31_N	0.819	0.93
38_N	43_I	0.818	0.93
395_L	404_T	0.818	0.93
248_I	395_L	0.816	0.93
313_Q	316_V	0.813	0.93
339_S	362_D	0.813	0.93
204_Q	208_S	0.813	0.93
344_G	381_G	0.813	0.93
28_Y	32_F	0.811	0.93
55_F	162_L	0.808	0.93
198_T	204_Q	0.808	0.93
67_L	70_T	0.808	0.93
345_N	349_F	0.808	0.93
339_S	407_I	0.806	0.92
298_S	301_E	0.804	0.92
554_R	559_F	0.804	0.92
35_G	42_K	0.803	0.92
136_I	140_K	0.801	0.92
527_A	531_L	0.800	0.92
202_A	206_I	0.799	0.92
46_F	54_L	0.798	0.92
309_Y	544_S	0.798	0.92
191_Y	196_N	0.797	0.92
354_E	357_K	0.796	0.92
146_E	150_K	0.793	0.92
287_N	502_R	0.793	0.92
24_T	33_N	0.793	0.92
201_D	205_N	0.791	0.92
51_S	57_L	0.791	0.92
161_I	165_L	0.790	0.92
244_G	335_K	0.789	0.92
242_A	465_I	0.787	0.92
551_K	554_R	0.785	0.91
350_W	355_M	0.783	0.91
273_L	506_F	0.783	0.91
219_D	224_E	0.782	0.91
416_G	436_N	0.782	0.91
444_L	448_I	0.781	0.91
215_A	219_D	0.781	0.91
296_K	299_D	0.779	0.91
70_T	74_V	0.778	0.91
112_L	115_S	0.775	0.91
554_R	558_P	0.773	0.91
205_N	209_N	0.771	0.91
89_Y	93_F	0.769	0.91
215_A	220_V	0.760	0.90
553_H	558_P	0.760	0.90
54_L	160_S	0.758	0.90
201_D	207_K	0.757	0.90
220_V	226_Y	0.756	0.90
305_E	403_Y	0.756	0.90
128_F	132_I	0.755	0.90
22_I	155_I	0.753	0.90
46_F	51_S	0.751	0.90
311_L	315_S	0.750	0.89
140_K	144_P	0.747	0.89
200_Y	204_Q	0.746	0.89
410_S	443_Y	0.744	0.89
276_L	506_F	0.744	0.89
246_N	462_D	0.744	0.89
216_D	219_D	0.743	0.89
303_M	408_T	0.743	0.89
400_Q	463_K	0.743	0.89
17_V	27_G	0.742	0.89
151_K	155_I	0.741	0.89
555_E	558_P	0.740	0.89
393_P	397_S	0.739	0.89
133_I	137_L	0.739	0.89
19_L	26_V	0.738	0.89
164_F	167_N	0.738	0.89
352_R	407_I	0.738	0.89
270_T	445_D	0.736	0.89
406_F	451_F	0.736	0.89
141_V	153_F	0.734	0.88
176_P	181_R	0.734	0.88
154_R	166_I	0.731	0.88
248_I	451_F	0.731	0.88
277_A	282_T	0.730	0.88
532_H	550_S	0.730	0.88
302_F	316_V	0.730	0.88
39_T	46_F	0.730	0.88
166_I	171_A	0.729	0.88
349_F	356_Y	0.728	0.88
370_Y	387_F	0.727	0.88
437_Y	441_A	0.725	0.88
13_F	20_L	0.724	0.88
505_L	548_I	0.721	0.88
312_A	315_S	0.719	0.87
176_P	182_S	0.719	0.87
227_M	231_Y	0.718	0.87
345_N	410_S	0.718	0.87
153_F	156_I	0.717	0.87
294_Q	300_A	0.716	0.87
26_V	30_L	0.715	0.87
340_A	394_L	0.714	0.87
449_E	452_F	0.713	0.87
365_F	394_L	0.713	0.87
165_L	172_E	0.713	0.87
21_W	25_Y	0.712	0.87
92_F	415_F	0.712	0.87
38_N	45_L	0.712	0.87
176_P	183_F	0.710	0.87
175_R	183_F	0.708	0.87
407_I	470_G	0.705	0.86
37_D	41_Q	0.705	0.86
348_T	353_N	0.704	0.86
300_A	523_D	0.704	0.86
172_E	175_R	0.700	0.86
240_G	245_K	0.697	0.86
256_Q	476_S	0.694	0.86
381_G	414_P	0.694	0.86
272_F	448_I	0.693	0.85
412_H	472_H	0.692	0.85
415_F	474_G	0.691	0.85
331_I	334_S	0.691	0.85
205_N	208_S	0.690	0.85
285_F	505_L	0.690	0.85
197_F	202_A	0.690	0.85
185_R	188_L	0.689	0.85
295_G	300_A	0.688	0.85
262_Y	269_V	0.687	0.85
284_Y	506_F	0.686	0.85
210_S	214_L	0.685	0.85
340_A	402_F	0.684	0.85
260_I	270_T	0.684	0.85
46_F	56_F	0.682	0.85
15_I	20_L	0.681	0.84
301_E	350_W	0.681	0.84
217_S	225_N	0.681	0.84
43_I	47_V	0.680	0.84
13_F	415_F	0.677	0.84
332_L	465_I	0.676	0.84
44_L	59_F	0.676	0.84
435_D	439_Q	0.675	0.84
44_L	51_S	0.674	0.84
337_Y	465_I	0.673	0.84
288_F	526_V	0.672	0.84
285_F	289_F	0.672	0.84
27_G	31_N	0.671	0.84
131_T	139_I	0.669	0.83
255_L	270_T	0.669	0.83
437_Y	440_S	0.669	0.83
499_Q	502_R	0.668	0.83
53_S	59_F	0.668	0.83
294_Q	297_T	0.665	0.83
202_A	208_S	0.665	0.83
290_H	473_Y	0.665	0.83
329_P	403_Y	0.664	0.83
163_V	166_I	0.663	0.83
184_D	188_L	0.662	0.83
355_M	359_E	0.661	0.83
147_T	152_S	0.661	0.83
247_V	403_Y	0.659	0.82
13_F	17_V	0.658	0.82
39_T	43_I	0.656	0.82
163_V	170_V	0.655	0.82
381_G	409_L	0.655	0.82
199_I	209_N	0.654	0.82
47_V	54_L	0.654	0.82
420_G	423_D	0.653	0.82
198_T	207_K	0.653	0.82
422_T	426_A	0.652	0.82
198_T	203_V	0.652	0.82
186_N	190_K	0.652	0.82
339_S	403_Y	0.649	0.82
122_P	126_F	0.649	0.82
20_L	24_T	0.649	0.82
167_N	170_V	0.649	0.82
360_G	530_I	0.648	0.81
473_Y	476_S	0.647	0.81
116_A	347_Q	0.646	0.81
395_L	451_F	0.645	0.81
57_L	64_K	0.644	0.81
408_T	451_F	0.644	0.81
44_L	52_S	0.644	0.81
131_T	135_I	0.642	0.81
418_D	422_T	0.641	0.81
45_L	54_L	0.640	0.81
266_G	274_N	0.639	0.81
264_I	274_N	0.638	0.80
72_I	75_I	0.638	0.80
296_K	300_A	0.636	0.80
175_R	181_R	0.636	0.80
53_S	58_G	0.635	0.80
298_S	350_W	0.631	0.80
343_H	409_L	0.631	0.80
294_Q	299_D	0.630	0.80
63_F	71_A	0.629	0.79
89_Y	98_T	0.629	0.79
253_E	384_D	0.628	0.79
475_I	500_L	0.628	0.79
156_I	174_D	0.628	0.79
50_L	57_L	0.627	0.79
171_A	175_R	0.626	0.79
118_S	413_F	0.625	0.79
251_S	407_I	0.625	0.79
15_I	18_V	0.625	0.79
133_I	139_I	0.624	0.79
90_Y	308_L	0.623	0.79
162_L	166_I	0.621	0.79
25_Y	29_V	0.619	0.78
361_I	407_I	0.618	0.78
236_N	239_F	0.618	0.78
47_V	59_F	0.617	0.78
452_F	461_Y	0.617	0.78
273_L	441_A	0.616	0.78
42_K	52_S	0.616	0.78
25_Y	32_F	0.616	0.78
178_L	181_R	0.615	0.78
243_E	457_K	0.614	0.78
40_I	44_L	0.613	0.78
138_A	142_N	0.612	0.78
271_P	276_L	0.610	0.77
51_S	61_L	0.609	0.77
352_R	364_F	0.609	0.77
23_K	29_V	0.609	0.77
54_L	57_L	0.608	0.77
260_I	506_F	0.606	0.77
199_I	204_Q	0.605	0.77
438_F	470_G	0.604	0.77
197_F	208_S	0.604	0.77
241_K	244_G	0.604	0.77
370_Y	390_E	0.604	0.77
212_R	216_D	0.603	0.77
421_D	424_F	0.601	0.76
302_F	306_N	0.601	0.76
446_Q	449_E	0.600	0.76
253_E	470_G	0.600	0.76
203_V	208_S	0.599	0.76
165_L	168_L	0.599	0.76
47_V	60_G	0.598	0.76
314_G	320_K	0.597	0.76
269_V	438_F	0.596	0.76
224_E	227_M	0.596	0.76
187_Y	190_K	0.595	0.76
48_N	60_G	0.595	0.76
343_H	350_W	0.595	0.76
239_F	532_H	0.595	0.76
44_L	48_N	0.594	0.76
42_K	45_L	0.594	0.76
124_D	128_F	0.593	0.75
213_A	216_D	0.593	0.75
179_L	183_F	0.593	0.75
381_G	451_F	0.593	0.75
424_F	439_Q	0.592	0.75
158_A	169_A	0.592	0.75
47_V	55_F	0.592	0.75
466_I	508_H	0.592	0.75
211_Q	216_D	0.591	0.75
165_L	173_S	0.591	0.75
149_S	169_A	0.591	0.75
451_F	466_I	0.591	0.75
17_V	24_T	0.590	0.75
288_F	291_Q	0.589	0.75
344_G	382_M	0.589	0.75
305_E	405_K	0.588	0.75
81_F	85_A	0.588	0.75
513_K	534_L	0.587	0.75
57_L	61_L	0.587	0.75
46_F	60_G	0.586	0.75
29_V	32_F	0.584	0.74
386_P	389_K	0.584	0.74
295_G	301_E	0.583	0.74
195_Y	202_A	0.582	0.74
387_F	391_S	0.581	0.74
156_I	173_S	0.581	0.74
45_L	52_S	0.581	0.74
494_D	498_A	0.579	0.74
179_L	182_S	0.579	0.74
408_T	444_L	0.578	0.74
221_T	224_E	0.578	0.74
15_I	26_V	0.577	0.73
273_L	282_T	0.577	0.73
208_S	214_L	0.576	0.73
278_H	281_E	0.575	0.73
285_F	288_F	0.574	0.73
149_S	160_S	0.574	0.73
362_D	389_K	0.574	0.73
553_H	559_F	0.573	0.73
134_L	138_A	0.573	0.73
333_K	339_S	0.573	0.73
23_K	30_L	0.573	0.73
516_K	519_K	0.572	0.73
199_I	208_S	0.570	0.73
175_R	179_L	0.568	0.72
422_T	425_P	0.568	0.72
312_A	319_N	0.566	0.72
41_Q	48_N	0.564	0.72
350_W	356_Y	0.564	0.72
342_F	387_F	0.564	0.72
16_A	19_L	0.564	0.72
344_G	387_F	0.562	0.71
494_D	518_H	0.561	0.71
245_K	511_G	0.559	0.71
185_R	195_Y	0.558	0.71
326_Q	334_S	0.558	0.71
159_S	162_L	0.557	0.71
184_D	191_Y	0.557	0.71
73_I	76_H	0.556	0.71
35_G	41_Q	0.554	0.70
13_F	19_L	0.554	0.70
346_T	367_S	0.554	0.70
375_E	389_K	0.554	0.70
444_L	523_D	0.554	0.70
178_L	182_S	0.553	0.70
24_T	30_L	0.552	0.70
206_I	210_S	0.552	0.70
19_L	29_V	0.550	0.70
156_I	168_L	0.550	0.70
340_A	365_F	0.550	0.70
126_F	129_I	0.550	0.70
157_F	168_L	0.548	0.70
167_N	174_D	0.547	0.69
332_L	403_Y	0.547	0.69
218_S	221_T	0.547	0.69
527_A	543_M	0.547	0.69
315_S	319_N	0.546	0.69
200_Y	203_V	0.545	0.69
165_L	174_D	0.544	0.69
385_K	421_D	0.544	0.69
141_V	149_S	0.544	0.69
14_L	24_T	0.543	0.69
17_V	23_K	0.542	0.69
269_V	274_N	0.541	0.69
159_S	170_V	0.541	0.69
145_A	148_S	0.541	0.69
498_A	501_Q	0.540	0.68
160_S	167_N	0.540	0.68
285_F	547_D	0.540	0.68
249_Y	526_V	0.539	0.68
231_Y	234_P	0.539	0.68
203_V	206_I	0.539	0.68
239_F	242_A	0.538	0.68
301_E	343_H	0.538	0.68
193_G	208_S	0.537	0.68
552_E	555_E	0.537	0.68
98_T	411_N	0.537	0.68
217_S	221_T	0.537	0.68
46_F	50_L	0.535	0.68
261_D	264_I	0.534	0.68
461_Y	464_S	0.534	0.68
197_F	200_Y	0.534	0.68
219_D	333_K	0.533	0.67
39_T	44_L	0.532	0.67
44_L	56_F	0.532	0.67
157_F	170_V	0.531	0.67
343_H	410_S	0.530	0.67
459_G	462_D	0.530	0.67
133_I	136_I	0.528	0.67
245_K	401_P	0.528	0.67
255_L	260_I	0.528	0.67
223_V	227_M	0.528	0.67
42_K	55_F	0.528	0.67
311_L	316_V	0.527	0.67
277_A	286_D	0.527	0.67
51_S	55_F	0.527	0.67
437_Y	470_G	0.527	0.67
155_I	171_A	0.526	0.66
48_N	61_L	0.526	0.66
155_I	161_I	0.526	0.66
72_I	76_H	0.526	0.66
281_E	513_K	0.526	0.66
59_F	64_K	0.526	0.66
165_L	170_V	0.526	0.66
524_V	528_P	0.525	0.66
245_K	464_S	0.525	0.66
47_V	57_L	0.525	0.66
246_N	465_I	0.524	0.66
43_I	48_N	0.524	0.66
344_G	409_L	0.523	0.66
263_K	274_N	0.523	0.66
204_Q	207_K	0.522	0.66
46_F	53_S	0.522	0.66
496_D	500_L	0.522	0.66
379_N	409_L	0.522	0.66
382_M	390_E	0.521	0.66
202_A	207_K	0.520	0.66
262_Y	273_L	0.519	0.65
437_Y	474_G	0.519	0.65
34_L	37_D	0.519	0.65
89_Y	95_D	0.519	0.65
351_N	356_Y	0.519	0.65
332_L	335_K	0.518	0.65
378_K	383_K	0.517	0.65
154_R	167_N	0.516	0.65
275_K	457_K	0.516	0.65
437_Y	473_Y	0.516	0.65
254_S	381_G	0.516	0.65
164_F	169_A	0.514	0.65
125_A	403_Y	0.514	0.65
274_N	277_A	0.514	0.65
378_K	410_S	0.512	0.64
298_S	310_P	0.512	0.64
217_S	222_E	0.511	0.64
269_V	449_E	0.511	0.64
505_L	521_A	0.511	0.64
387_F	409_L	0.510	0.64
46_F	61_L	0.510	0.64
285_F	290_H	0.510	0.64
345_N	415_F	0.509	0.64
335_K	531_L	0.509	0.64
290_H	294_Q	0.508	0.64
551_K	557_I	0.507	0.64
254_S	472_H	0.506	0.63
48_N	58_G	0.506	0.63
254_S	415_F	0.505	0.63
247_V	530_I	0.505	0.63
86_N	89_Y	0.505	0.63
395_L	460_L	0.504	0.63
158_A	173_S	0.503	0.63
295_G	350_W	0.503	0.63
187_Y	194_T	0.502	0.63
240_G	243_E	0.502	0.63
247_V	255_L	0.502	0.63
89_Y	298_S	0.501	0.63
86_N	198_T	0.501	0.63
149_S	153_F	0.500	0.63

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2w8dA	1	0.641	100	0.418	Contact Map
2w5qA	1	0.641	100	0.436	Contact Map
4uorA	3	0.6379	100	0.45	Contact Map
4uopA	2	0.6009	100	0.486	Contact Map
3lxqA	1	0.5932	100	0.529	Contact Map
4upiA	2	0.6009	100	0.53	Contact Map
3ed4A	3	0.5963	100	0.531	Contact Map
4uplA	2	0.6055	100	0.532	Contact Map
4uphA	2	0.5763	100	0.533	Contact Map
1fsuA	1	0.5809	100	0.535	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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