YERA - BACSU - GREMLIN Contacts

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YERA - Putative adenine deaminase YerA

UniProt:	O34909	Sequences: MSERTFNWKNKDIRAQVDVVDSKLLPTLLLRNALVLNPYVKQWLKKNIWIYQDRIVYVGHELPNRAEEIHTIDCEGKYIVPGYIEPHAHPFQIYNPQTLAEYVSQYGTTTFVNDNLFLLLQSGKKKALTILNELKKQPVQYFWWSRYDLQTEVLNEDHVLPFDVRKQWIEHPDVIQGGEMTGWPRLVDGDDLMLHCMQATKKQRKRIEGHFPGASDKTLTKMKLFGADCDHEAMTGDEVMRRLELGYYVSLRNSSIRPDVRKILQELHEKGFRYYDHFFYTTDGATPNFYKGGMTNELIRIALEEGVPAIDAYNMASFNIAKYYQMDDYLGVVGPGRLASLNILEDPLNPNPVTVLSKGTILRENGCDLKAFTKTDWHKGGLVPLELSYDMTMDDLQFSMPMGVKMRNAVIMEPYMIEIDNSMEQLSFDHDESYLTMLDRHGKWRVNTMIKGFASSVQGFVSSFTTTGDIVAIGKNKADMLLAFARMKEIGGGIVLAENGNILHEIPLALCGCASSEAYEDVLEKEQKLRDLLTERGYEFCDPIYTLLFLQSTHLPYIRITPRGIFDVMKKTVLFPSIMR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	580 (552)
Sequences:	1540 (1148)
Seq/√Len:	48.9

ECOLI - ADEC
BACSU - YERA ADEC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
30_L	74_C	4.951	1.00
486_R	505_E	4.305	1.00
486_R	489_E	4.121	1.00
48_I	79_I	3.947	1.00
472_A	480_M	3.924	1.00
517_E	521_D	3.476	1.00
35_V	46_K	3.377	1.00
161_P	164_V	3.375	1.00
476_N	479_D	3.353	1.00
434_Y	477_K	3.254	1.00
106_Y	296_N	3.220	1.00
83_Y	350_P	3.219	1.00
457_V	498_E	3.145	1.00
296_N	300_R	3.098	1.00
42_Q	244_E	3.082	1.00
356_L	361_I	3.082	1.00
74_C	343_I	3.056	1.00
18_D	23_K	3.049	1.00
345_E	351_N	2.981	1.00
98_T	101_E	2.976	1.00
180_M	193_M	2.877	1.00
33_A	79_I	2.874	1.00
435_L	560_I	2.872	1.00
19_V	56_V	2.757	1.00
280_Y	284_G	2.756	1.00
436_T	480_M	2.738	1.00
557_Y	569_M	2.712	1.00
436_T	472_A	2.627	1.00
461_V	483_A	2.576	1.00
517_E	525_K	2.569	1.00
470_I	484_F	2.555	1.00
29_L	68_E	2.504	1.00
80_V	344_L	2.492	1.00
490_I	505_E	2.462	1.00
79_I	341_L	2.459	1.00
34_L	45_K	2.451	1.00
281_T	284_G	2.436	1.00
155_N	562_P	2.375	1.00
479_D	500_G	2.351	1.00
79_I	343_I	2.345	1.00
450_I	550_L	2.331	1.00
404_V	451_K	2.318	1.00
404_V	415_Y	2.308	1.00
33_A	74_C	2.306	1.00
37_N	40_V	2.299	1.00
393_M	478_A	2.294	1.00
30_L	343_I	2.287	1.00
182_G	185_R	2.271	1.00
345_E	353_V	2.269	1.00
276_D	322_K	2.265	1.00
128_L	171_H	2.195	1.00
135_K	173_D	2.143	1.00
280_Y	302_A	2.122	1.00
404_V	413_E	2.072	1.00
291_K	527_Q	2.063	1.00
413_E	557_Y	2.057	1.00
277_H	282_T	2.025	1.00
303_L	350_P	2.018	1.00
36_L	80_V	1.978	0.99
77_K	353_V	1.977	0.99
482_L	486_R	1.975	0.99
472_A	484_F	1.969	0.99
496_L	532_L	1.966	0.99
453_F	473_I	1.964	0.99
39_Y	332_V	1.963	0.99
132_N	135_K	1.958	0.99
354_T	361_I	1.929	0.99
463_S	470_I	1.927	0.99
485_A	488_K	1.917	0.99
567_D	570_K	1.912	0.99
34_L	43_W	1.895	0.99
427_S	430_H	1.894	0.99
36_L	43_W	1.839	0.99
299_I	342_N	1.823	0.99
481_L	485_A	1.807	0.99
313_Y	350_P	1.806	0.99
277_H	284_G	1.805	0.99
18_D	24_L	1.805	0.99
145_S	165_R	1.782	0.99
333_V	341_L	1.778	0.99
346_D	349_N	1.771	0.99
414_P	574_L	1.741	0.99
35_V	48_I	1.739	0.99
119_L	127_A	1.732	0.99
77_K	343_I	1.717	0.98
220_T	245_L	1.709	0.98
504_H	532_L	1.709	0.98
261_R	305_E	1.675	0.98
108_T	294_M	1.672	0.98
261_R	301_I	1.667	0.98
128_L	132_N	1.653	0.98
396_L	484_F	1.653	0.98
140_Q	330_L	1.645	0.98
122_S	511_C	1.631	0.98
94_Y	522_V	1.630	0.98
487_M	495_V	1.628	0.98
279_F	282_T	1.627	0.98
197_M	207_I	1.625	0.98
313_Y	317_S	1.624	0.98
490_I	495_V	1.615	0.98
55_I	341_L	1.607	0.98
482_L	500_G	1.605	0.98
363_R	366_G	1.599	0.98
72_I	356_L	1.590	0.97
41_K	311_D	1.586	0.97
27_T	51_Y	1.583	0.97
155_N	563_R	1.583	0.97
37_N	44_L	1.579	0.97
343_I	356_L	1.576	0.97
37_N	42_Q	1.574	0.97
486_R	490_I	1.563	0.97
19_V	51_Y	1.554	0.97
275_Y	282_T	1.545	0.97
15_A	51_Y	1.531	0.97
21_D	218_T	1.529	0.97
497_A	502_I	1.525	0.97
32_N	73_D	1.517	0.97
153_V	566_F	1.514	0.97
301_I	305_E	1.511	0.96
438_L	484_F	1.510	0.96
387_L	488_K	1.499	0.96
90_P	141_Y	1.499	0.96
279_F	284_G	1.484	0.96
243_L	278_F	1.462	0.96
36_L	313_Y	1.455	0.96
105_Q	363_R	1.454	0.96
509_A	516_S	1.451	0.96
140_Q	358_K	1.449	0.96
338_L	358_K	1.445	0.95
229_C	323_Y	1.443	0.95
41_K	314_N	1.435	0.95
354_T	364_E	1.432	0.95
56_V	224_L	1.424	0.95
170_E	203_Q	1.423	0.95
280_Y	295_T	1.419	0.95
393_M	481_L	1.410	0.95
25_L	69_I	1.403	0.95
28_L	50_I	1.386	0.94
77_K	345_E	1.382	0.94
558_I	574_L	1.377	0.94
48_I	333_V	1.374	0.94
140_Q	357_S	1.372	0.94
432_E	449_M	1.371	0.94
240_M	244_E	1.363	0.94
102_Y	519_Y	1.358	0.94
182_G	190_D	1.357	0.94
553_T	561_T	1.353	0.94
433_S	475_K	1.349	0.93
391_M	481_L	1.344	0.93
314_N	318_F	1.343	0.93
144_W	176_Q	1.339	0.93
277_H	280_Y	1.335	0.93
15_A	52_Q	1.315	0.93
26_P	49_W	1.315	0.93
257_R	410_V	1.314	0.92
299_I	316_A	1.295	0.92
438_L	463_S	1.292	0.92
125_K	128_L	1.285	0.92
299_I	303_L	1.283	0.92
248_Y	279_F	1.278	0.91
463_S	484_F	1.275	0.91
281_T	324_Y	1.274	0.91
232_E	252_R	1.273	0.91
301_I	304_E	1.272	0.91
250_S	281_T	1.271	0.91
487_M	490_I	1.269	0.91
128_L	167_Q	1.264	0.91
36_L	310_I	1.263	0.91
275_Y	284_G	1.255	0.91
457_V	475_K	1.253	0.91
398_F	449_M	1.249	0.90
307_V	315_M	1.245	0.90
223_K	247_Y	1.239	0.90
30_L	50_I	1.237	0.90
50_I	341_L	1.231	0.90
566_F	573_V	1.223	0.89
41_K	310_I	1.219	0.89
128_L	168_W	1.215	0.89
166_K	202_K	1.213	0.89
495_V	505_E	1.212	0.89
180_M	185_R	1.210	0.89
496_L	536_R	1.209	0.89
15_A	24_L	1.202	0.89
531_D	535_E	1.195	0.88
155_N	445_R	1.192	0.88
507_P	525_K	1.191	0.88
68_E	71_T	1.189	0.88
251_L	264_L	1.188	0.88
248_Y	322_K	1.182	0.88
465_T	471_V	1.179	0.88
385_L	491_G	1.176	0.88
135_K	171_H	1.172	0.87
267_L	315_M	1.167	0.87
253_N	261_R	1.163	0.87
421_N	424_E	1.158	0.87
510_L	516_S	1.158	0.87
417_I	451_K	1.154	0.87
385_L	463_S	1.152	0.86
274_Y	282_T	1.152	0.86
18_D	189_G	1.151	0.86
124_K	168_W	1.150	0.86
461_V	472_A	1.149	0.86
39_Y	337_R	1.148	0.86
98_T	519_Y	1.148	0.86
515_S	522_V	1.147	0.86
36_L	78_Y	1.146	0.86
445_R	562_P	1.145	0.86
344_L	350_P	1.144	0.86
479_D	482_L	1.142	0.86
131_L	173_D	1.141	0.86
86_P	281_T	1.136	0.86
341_L	356_L	1.136	0.86
219_L	241_R	1.135	0.86
486_R	495_V	1.134	0.86
396_L	403_G	1.133	0.86
474_G	480_M	1.132	0.85
95_N	510_L	1.131	0.85
521_D	524_E	1.126	0.85
134_L	173_D	1.120	0.85
144_W	175_I	1.119	0.85
248_Y	323_Y	1.115	0.85
439_D	444_W	1.114	0.85
344_L	352_P	1.110	0.84
396_L	481_L	1.110	0.84
259_D	409_A	1.108	0.84
428_F	433_S	1.107	0.84
487_M	491_G	1.106	0.84
43_W	78_Y	1.105	0.84
295_T	316_A	1.103	0.84
49_W	59_G	1.101	0.84
19_V	26_P	1.096	0.84
18_D	21_D	1.092	0.83
134_L	137_Q	1.087	0.83
103_V	111_F	1.085	0.83
438_L	446_V	1.084	0.83
471_V	551_Q	1.081	0.83
44_L	244_E	1.080	0.83
249_V	266_E	1.079	0.83
518_A	521_D	1.079	0.83
113_N	143_W	1.070	0.82
111_F	139_V	1.067	0.82
153_V	573_V	1.063	0.82
50_I	356_L	1.062	0.82
33_A	343_I	1.062	0.82
105_Q	139_V	1.057	0.81
236_G	266_E	1.051	0.81
122_S	381_G	1.051	0.81
274_Y	284_G	1.048	0.81
250_S	324_Y	1.046	0.81
383_V	491_G	1.044	0.80
299_I	317_S	1.043	0.80
229_C	324_Y	1.042	0.80
43_W	347_P	1.042	0.80
330_L	338_L	1.041	0.80
303_L	309_A	1.041	0.80
394_D	397_Q	1.039	0.80
248_Y	277_H	1.031	0.80
100_A	138_P	1.030	0.80
504_H	528_K	1.023	0.79
483_A	497_A	1.022	0.79
83_Y	342_N	1.022	0.79
332_V	337_R	1.021	0.79
169_I	205_K	1.020	0.79
436_T	484_F	1.016	0.79
309_A	312_A	1.016	0.79
140_Q	338_L	1.014	0.78
314_N	319_N	1.013	0.78
435_L	473_I	1.010	0.78
80_V	342_N	1.007	0.78
118_L	126_K	1.004	0.78
32_N	75_E	1.001	0.78
33_A	341_L	1.000	0.77
28_L	72_I	1.000	0.77
110_T	142_F	0.998	0.77
184_P	571_K	0.998	0.77
361_I	364_E	0.997	0.77
29_L	49_W	0.997	0.77
415_Y	451_K	0.994	0.77
31_R	71_T	0.994	0.77
145_S	168_W	0.992	0.77
88_A	99_L	0.989	0.77
212_P	242_R	0.982	0.76
78_Y	347_P	0.982	0.76
328_D	338_L	0.980	0.76
259_D	262_K	0.979	0.76
40_V	244_E	0.976	0.76
279_F	323_Y	0.974	0.76
396_L	480_M	0.974	0.76
182_G	193_M	0.973	0.76
154_L	562_P	0.973	0.76
397_Q	423_M	0.969	0.75
450_I	453_F	0.968	0.75
116_L	468_G	0.967	0.75
46_K	58_V	0.965	0.75
414_P	558_I	0.964	0.75
274_Y	280_Y	0.960	0.75
124_K	167_Q	0.959	0.74
29_L	71_T	0.957	0.74
275_Y	280_Y	0.957	0.74
307_V	312_A	0.951	0.74
189_G	194_L	0.951	0.74
438_L	470_I	0.950	0.74
435_L	550_L	0.949	0.74
185_R	193_M	0.948	0.74
30_L	356_L	0.947	0.74
435_L	448_T	0.944	0.73
55_I	58_V	0.944	0.73
473_I	547_L	0.944	0.73
92_Q	99_L	0.940	0.73
20_V	221_K	0.939	0.73
236_G	240_M	0.937	0.73
471_V	560_I	0.933	0.72
38_P	332_V	0.933	0.72
104_S	139_V	0.931	0.72
277_H	322_K	0.928	0.72
420_D	425_Q	0.922	0.72
22_S	217_K	0.921	0.71
116_L	181_T	0.921	0.71
181_T	554_H	0.921	0.71
35_V	58_V	0.914	0.71
125_K	380_G	0.913	0.71
462_S	548_L	0.907	0.70
524_E	528_K	0.907	0.70
255_S	324_Y	0.906	0.70
195_H	199_A	0.901	0.70
525_K	528_K	0.901	0.70
130_I	514_A	0.901	0.70
86_P	320_I	0.899	0.70
299_I	313_Y	0.899	0.70
127_A	168_W	0.897	0.69
82_G	109_T	0.897	0.69
142_F	175_I	0.893	0.69
117_F	466_T	0.892	0.69
186_L	197_M	0.887	0.69
111_F	141_Y	0.886	0.68
194_L	197_M	0.885	0.68
127_A	145_S	0.885	0.68
238_E	241_R	0.884	0.68
79_I	333_V	0.883	0.68
19_V	24_L	0.882	0.68
303_L	313_Y	0.882	0.68
86_P	324_Y	0.881	0.68
482_L	502_I	0.881	0.68
169_I	199_A	0.880	0.68
99_L	111_F	0.880	0.68
239_V	266_E	0.879	0.68
31_R	47_N	0.879	0.68
148_D	185_R	0.879	0.68
91_F	468_G	0.878	0.68
566_F	571_K	0.877	0.68
118_L	130_I	0.875	0.67
245_L	335_P	0.875	0.67
406_M	413_E	0.874	0.67
17_V	189_G	0.873	0.67
216_D	241_R	0.873	0.67
48_I	58_V	0.872	0.67
91_F	116_L	0.870	0.67
148_D	181_T	0.867	0.67
117_F	468_G	0.866	0.67
215_S	241_R	0.861	0.66
28_L	356_L	0.861	0.66
91_F	552_S	0.857	0.66
461_V	484_F	0.856	0.66
91_F	117_F	0.855	0.66
229_C	281_T	0.854	0.66
198_Q	202_K	0.854	0.66
295_T	298_L	0.854	0.66
97_Q	133_E	0.852	0.65
206_R	323_Y	0.850	0.65
166_K	199_A	0.848	0.65
460_F	533_L	0.847	0.65
391_M	396_L	0.844	0.65
74_C	79_I	0.843	0.65
560_I	565_I	0.842	0.64
29_L	47_N	0.836	0.64
498_E	503_L	0.834	0.64
281_T	316_A	0.834	0.64
457_V	499_N	0.833	0.64
303_L	346_D	0.831	0.63
103_V	139_V	0.830	0.63
450_I	473_I	0.828	0.63
433_S	473_I	0.828	0.63
122_S	126_K	0.826	0.63
49_W	57_Y	0.826	0.63
318_F	322_K	0.825	0.63
364_E	367_C	0.824	0.63
381_G	384_P	0.820	0.62
216_D	219_L	0.818	0.62
277_H	281_T	0.818	0.62
70_H	360_T	0.818	0.62
464_F	513_C	0.817	0.62
427_S	431_D	0.816	0.62
234_M	411_I	0.812	0.62
116_L	149_L	0.811	0.62
129_T	133_E	0.810	0.61
253_N	301_I	0.810	0.61
36_L	347_P	0.808	0.61
160_L	165_R	0.807	0.61
482_L	497_A	0.807	0.61
506_I	522_V	0.806	0.61
169_I	200_T	0.804	0.61
239_V	249_V	0.801	0.61
169_I	255_S	0.801	0.61
86_P	250_S	0.798	0.60
476_N	480_M	0.797	0.60
166_K	203_Q	0.797	0.60
458_Q	479_D	0.797	0.60
417_I	449_M	0.796	0.60
37_N	332_V	0.794	0.60
88_A	92_Q	0.793	0.60
461_V	487_M	0.793	0.60
250_S	279_F	0.792	0.60
346_D	351_N	0.789	0.59
537_G	543_P	0.788	0.59
100_A	137_Q	0.788	0.59
108_T	545_Y	0.787	0.59
99_L	103_V	0.787	0.59
23_K	241_R	0.784	0.59
142_F	330_L	0.781	0.59
165_R	169_I	0.781	0.59
406_M	409_A	0.780	0.59
417_I	427_S	0.779	0.58
117_F	552_S	0.774	0.58
257_R	549_F	0.773	0.58
156_E	467_T	0.772	0.58
112_V	324_Y	0.772	0.58
532_L	535_E	0.772	0.58
486_R	502_I	0.770	0.58
533_L	542_D	0.770	0.58
353_V	365_N	0.768	0.57
509_A	515_S	0.767	0.57
363_R	368_D	0.767	0.57
261_R	304_E	0.765	0.57
468_G	552_S	0.764	0.57
99_L	294_M	0.763	0.57
396_L	402_M	0.761	0.57
134_L	141_Y	0.758	0.56
91_F	181_T	0.757	0.56
503_L	536_R	0.757	0.56
43_W	310_I	0.757	0.56
274_Y	277_H	0.756	0.56
34_L	78_Y	0.755	0.56
273_R	284_G	0.755	0.56
70_H	361_I	0.753	0.56
215_S	251_L	0.748	0.55
147_Y	177_G	0.748	0.55
131_L	143_W	0.746	0.55
35_V	341_L	0.746	0.55
147_Y	468_G	0.745	0.55
137_Q	141_Y	0.745	0.55
145_S	174_V	0.744	0.55
480_M	484_F	0.742	0.55
16_Q	56_V	0.741	0.55
521_D	525_K	0.741	0.55
465_T	551_Q	0.741	0.55
84_I	112_V	0.740	0.55
106_Y	352_P	0.737	0.54
431_D	454_A	0.734	0.54
264_L	307_V	0.732	0.54
119_L	230_D	0.732	0.54
275_Y	311_D	0.731	0.54
27_T	69_I	0.729	0.53
181_T	468_G	0.727	0.53
147_Y	181_T	0.727	0.53
378_H	381_G	0.727	0.53
116_L	552_S	0.726	0.53
427_S	449_M	0.726	0.53
352_P	355_V	0.726	0.53
460_F	496_L	0.724	0.53
426_L	477_K	0.724	0.53
467_T	553_T	0.724	0.53
167_Q	170_E	0.723	0.53
410_V	555_L	0.721	0.53
84_I	321_A	0.721	0.53
398_F	402_M	0.719	0.52
276_D	314_N	0.717	0.52
57_Y	61_E	0.714	0.52
38_P	314_N	0.713	0.52
249_V	278_F	0.712	0.52
117_F	121_Q	0.712	0.52
165_R	199_A	0.712	0.52
90_P	96_P	0.711	0.52
390_D	488_K	0.710	0.52
94_Y	519_Y	0.708	0.51
326_M	330_L	0.705	0.51
192_L	196_C	0.704	0.51
274_Y	278_F	0.704	0.51
191_D	195_H	0.704	0.51
424_E	427_S	0.703	0.51
91_F	284_G	0.701	0.51
92_Q	103_V	0.700	0.50
154_L	553_T	0.699	0.50
164_V	167_Q	0.698	0.50
393_M	396_L	0.698	0.50
422_S	426_L	0.698	0.50
263_I	266_E	0.697	0.50
207_I	227_A	0.697	0.50
506_I	525_K	0.694	0.50
70_H	364_E	0.694	0.50
91_F	147_Y	0.693	0.50
311_D	314_N	0.692	0.50
417_I	424_E	0.692	0.50
479_D	499_N	0.691	0.50
120_L	468_G	0.690	0.49
273_R	282_T	0.689	0.49
93_I	464_F	0.688	0.49
16_Q	19_V	0.688	0.49
211_F	242_R	0.688	0.49
23_K	189_G	0.687	0.49
378_H	385_L	0.687	0.49
396_L	436_T	0.685	0.49
420_D	426_L	0.685	0.49
422_S	427_S	0.683	0.49
72_I	361_I	0.683	0.49
38_P	310_I	0.682	0.49
334_G	337_R	0.680	0.48
294_M	545_Y	0.679	0.48
223_K	245_L	0.677	0.48
292_G	297_E	0.675	0.48
431_D	452_G	0.675	0.48
388_S	488_K	0.675	0.48
463_S	490_I	0.674	0.48
229_C	250_S	0.673	0.48
36_L	344_L	0.672	0.48
251_L	280_Y	0.671	0.48
119_L	168_W	0.669	0.47
148_D	554_H	0.668	0.47
24_L	51_Y	0.667	0.47
275_Y	315_M	0.665	0.47
131_L	171_H	0.665	0.47
276_D	319_N	0.665	0.47
165_R	197_M	0.665	0.47
120_L	157_D	0.664	0.47
116_L	554_H	0.663	0.47
400_M	403_G	0.662	0.47
400_M	424_E	0.659	0.46
242_R	249_V	0.659	0.46
285_A	289_F	0.659	0.46
82_G	340_S	0.658	0.46
116_L	466_T	0.658	0.46
428_F	475_K	0.657	0.46
453_F	462_S	0.657	0.46
149_L	181_T	0.656	0.46
155_N	444_W	0.655	0.46
313_Y	347_P	0.655	0.46
262_K	265_Q	0.654	0.46
187_V	221_K	0.654	0.46
219_L	245_L	0.654	0.46
427_S	432_E	0.654	0.46
237_D	241_R	0.651	0.46
447_N	560_I	0.649	0.45
113_N	178_G	0.648	0.45
280_Y	316_A	0.647	0.45
343_I	353_V	0.647	0.45
275_Y	281_T	0.646	0.45
308_P	311_D	0.646	0.45
55_I	333_V	0.646	0.45
533_L	536_R	0.646	0.45
91_F	554_H	0.644	0.45
563_R	573_V	0.640	0.44
360_T	367_C	0.640	0.44
116_L	120_L	0.639	0.44
86_P	465_T	0.639	0.44
489_E	505_E	0.638	0.44
233_A	238_E	0.637	0.44
219_L	223_K	0.637	0.44
84_I	320_I	0.637	0.44
99_L	559_R	0.635	0.44
433_S	450_I	0.635	0.44
42_Q	273_R	0.635	0.44
313_Y	344_L	0.634	0.44
82_G	317_S	0.633	0.44
251_L	267_L	0.633	0.44
417_I	430_H	0.633	0.44
138_P	560_I	0.632	0.44
83_Y	317_S	0.629	0.43
303_L	345_E	0.628	0.43
100_A	515_S	0.626	0.43
71_T	75_E	0.626	0.43
72_I	354_T	0.625	0.43
327_D	337_R	0.624	0.43
232_E	254_S	0.623	0.43
88_A	294_M	0.622	0.43
79_I	374_K	0.622	0.43
314_N	317_S	0.619	0.42
110_T	328_D	0.619	0.42
116_L	147_Y	0.619	0.42
148_D	467_T	0.616	0.42
192_L	195_H	0.616	0.42
499_N	502_I	0.616	0.42
151_T	553_T	0.615	0.42
30_L	341_L	0.615	0.42
120_L	181_T	0.614	0.42
117_F	149_L	0.614	0.42
30_L	79_I	0.613	0.42
110_T	140_Q	0.613	0.42
120_L	149_L	0.613	0.42
175_I	186_L	0.613	0.42
250_S	323_Y	0.612	0.42
437_M	562_P	0.610	0.41
464_F	494_I	0.610	0.41
163_D	195_H	0.608	0.41
108_T	463_S	0.608	0.41
120_L	552_S	0.607	0.41
117_F	181_T	0.607	0.41
199_A	203_Q	0.606	0.41
346_D	356_L	0.606	0.41
528_K	532_L	0.606	0.41
279_F	320_I	0.605	0.41
119_L	160_L	0.604	0.41
205_K	510_L	0.604	0.41
515_S	518_A	0.604	0.41
303_L	352_P	0.604	0.41
431_D	475_K	0.604	0.41
213_G	411_I	0.603	0.41
37_N	337_R	0.603	0.41
309_A	313_Y	0.603	0.41
265_Q	268_H	0.603	0.41
149_L	552_S	0.603	0.41
530_R	542_D	0.601	0.41
121_Q	466_T	0.600	0.40
116_L	148_D	0.600	0.40
45_K	75_E	0.600	0.40
124_K	164_V	0.599	0.40
151_T	562_P	0.599	0.40
236_G	239_V	0.599	0.40
149_L	468_G	0.598	0.40
96_P	377_W	0.598	0.40
51_Y	56_V	0.597	0.40
390_D	393_M	0.596	0.40
108_T	212_P	0.595	0.40
80_V	83_Y	0.594	0.40
100_A	134_L	0.593	0.40
121_Q	441_H	0.593	0.40
193_M	196_C	0.592	0.40
379_K	383_V	0.592	0.40
208_E	229_C	0.590	0.40
179_E	210_H	0.589	0.39
342_N	352_P	0.589	0.39
476_N	499_N	0.588	0.39
213_G	235_T	0.588	0.39
162_F	195_H	0.588	0.39
168_W	171_H	0.587	0.39
103_V	289_F	0.587	0.39
121_Q	157_D	0.586	0.39
396_L	400_M	0.586	0.39
49_W	61_E	0.586	0.39
243_L	249_V	0.585	0.39
118_L	511_C	0.584	0.39
317_S	321_A	0.584	0.39
421_N	478_A	0.583	0.39
30_L	152_E	0.581	0.39
515_S	525_K	0.581	0.39
236_G	265_Q	0.580	0.39
251_L	301_I	0.579	0.38
77_K	344_L	0.579	0.38
121_Q	149_L	0.578	0.38
509_A	517_E	0.577	0.38
211_F	238_E	0.576	0.38
196_C	549_F	0.576	0.38
388_S	531_D	0.576	0.38
211_F	214_A	0.575	0.38
280_Y	298_L	0.574	0.38
126_K	511_C	0.574	0.38
85_E	294_M	0.573	0.38
264_L	267_L	0.572	0.38
533_L	538_Y	0.572	0.38
133_E	136_K	0.572	0.38
414_P	567_D	0.571	0.38
181_T	552_S	0.570	0.38
80_V	333_V	0.570	0.38
303_L	318_F	0.569	0.37
233_A	259_D	0.569	0.37
120_L	469_D	0.568	0.37
92_Q	229_C	0.567	0.37
103_V	108_T	0.566	0.37
49_W	68_E	0.566	0.37
390_D	398_F	0.566	0.37
238_E	437_M	0.566	0.37
438_L	472_A	0.565	0.37
417_I	432_E	0.564	0.37
50_I	299_I	0.563	0.37
426_L	449_M	0.562	0.37
378_H	384_P	0.562	0.37
104_S	357_S	0.562	0.37
83_Y	307_V	0.560	0.37
117_F	147_Y	0.560	0.37
265_Q	305_E	0.560	0.37
534_T	572_T	0.560	0.37
388_S	443_K	0.559	0.37
83_Y	352_P	0.558	0.36
120_L	150_Q	0.558	0.36
244_E	499_N	0.557	0.36
140_Q	340_S	0.556	0.36
21_D	187_V	0.555	0.36
220_T	296_N	0.555	0.36
448_T	560_I	0.554	0.36
254_S	434_Y	0.553	0.36
117_F	120_L	0.553	0.36
17_V	194_L	0.552	0.36
452_G	561_T	0.551	0.36
83_Y	344_L	0.551	0.36
410_V	559_R	0.551	0.36
256_I	546_T	0.551	0.36
496_L	544_I	0.550	0.36
468_G	554_H	0.549	0.36
455_S	536_R	0.549	0.36
242_R	424_E	0.549	0.36
70_H	354_T	0.548	0.36
344_L	353_V	0.548	0.36
544_I	548_L	0.547	0.35
304_E	349_N	0.547	0.35
91_F	149_L	0.546	0.35
239_V	317_S	0.546	0.35
161_P	192_L	0.546	0.35
16_Q	52_Q	0.545	0.35
156_E	165_R	0.545	0.35
299_I	350_P	0.545	0.35
220_T	335_P	0.544	0.35
126_K	130_I	0.544	0.35
129_T	132_N	0.543	0.35
228_D	328_D	0.542	0.35
441_H	444_W	0.542	0.35
253_N	258_P	0.541	0.35
92_Q	469_D	0.540	0.35
463_S	483_A	0.540	0.35
137_Q	370_K	0.540	0.35
37_N	245_L	0.540	0.35
181_T	466_T	0.539	0.35
50_I	343_I	0.539	0.35
88_A	282_T	0.538	0.35
496_L	529_L	0.538	0.35
264_L	501_N	0.537	0.35
50_I	235_T	0.536	0.34
297_E	300_R	0.536	0.34
174_V	205_K	0.535	0.34
317_S	320_I	0.535	0.34
241_R	245_L	0.535	0.34
453_F	543_P	0.534	0.34
93_I	508_L	0.534	0.34
157_D	468_G	0.533	0.34
84_I	110_T	0.533	0.34
48_I	358_K	0.532	0.34
99_L	242_R	0.532	0.34
21_D	221_K	0.532	0.34
149_L	466_T	0.531	0.34
37_N	43_W	0.531	0.34
431_D	451_K	0.531	0.34
102_Y	259_D	0.531	0.34
150_Q	468_G	0.531	0.34
144_W	208_E	0.530	0.34
399_S	501_N	0.530	0.34
26_P	29_L	0.529	0.34
466_T	552_S	0.527	0.34
124_K	128_L	0.527	0.34
198_Q	201_K	0.527	0.34
29_L	137_Q	0.526	0.34
310_I	313_Y	0.526	0.34
441_H	552_S	0.526	0.34
398_F	403_G	0.525	0.33
426_L	432_E	0.525	0.33
478_A	500_G	0.524	0.33
382_L	516_S	0.524	0.33
116_L	121_Q	0.523	0.33
557_Y	567_D	0.523	0.33
23_K	187_V	0.523	0.33
54_R	327_D	0.523	0.33
148_D	182_G	0.522	0.33
147_Y	552_S	0.522	0.33
243_L	307_V	0.522	0.33
380_G	384_P	0.522	0.33
47_N	68_E	0.522	0.33
182_G	449_M	0.522	0.33
145_S	169_I	0.521	0.33
481_L	488_K	0.520	0.33
77_K	356_L	0.520	0.33
91_F	466_T	0.520	0.33
550_L	559_R	0.519	0.33
235_T	238_E	0.519	0.33
178_G	409_A	0.519	0.33
16_Q	54_R	0.518	0.33
208_E	549_F	0.518	0.33
57_Y	220_T	0.518	0.33
213_G	257_R	0.517	0.33
501_N	524_E	0.517	0.33
420_D	528_K	0.517	0.33
300_R	352_P	0.516	0.33
436_T	481_L	0.515	0.33
469_D	552_S	0.514	0.32
335_P	558_I	0.514	0.32
478_A	482_L	0.513	0.32
80_V	313_Y	0.513	0.32
49_W	220_T	0.512	0.32
212_P	545_Y	0.512	0.32
94_Y	102_Y	0.512	0.32
91_F	148_D	0.512	0.32
229_C	249_V	0.512	0.32
420_D	489_E	0.510	0.32
284_G	468_G	0.510	0.32
47_N	61_E	0.510	0.32
243_L	263_I	0.510	0.32
36_L	350_P	0.509	0.32
468_G	513_C	0.509	0.32
432_E	448_T	0.509	0.32
479_D	502_I	0.508	0.32
229_C	566_F	0.508	0.32
223_K	335_P	0.507	0.32
243_L	266_E	0.507	0.32
111_F	496_L	0.507	0.32
396_L	401_P	0.506	0.32
212_P	294_M	0.505	0.32
303_L	348_L	0.505	0.32
144_W	178_G	0.505	0.32
91_F	120_L	0.505	0.32
237_D	499_N	0.504	0.32
367_C	478_A	0.504	0.32
163_D	531_D	0.504	0.32
178_G	256_I	0.503	0.31
157_D	441_H	0.503	0.31
304_E	410_V	0.502	0.31
37_N	357_S	0.502	0.31
266_E	278_F	0.502	0.31
410_V	549_F	0.502	0.31
256_I	259_D	0.502	0.31
559_R	565_I	0.501	0.31
381_G	386_E	0.501	0.31
43_W	313_Y	0.500	0.31
195_H	536_R	0.500	0.31

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3nqbA	2	0.981	100	0.334	Contact Map
2icsA	1	0.5552	100	0.793	Contact Map
2vunA	3	0.5828	100	0.796	Contact Map
2ogjA	4	0.5741	100	0.797	Contact Map
3mtwA	5	0.5724	100	0.799	Contact Map
4whbE	3	0.5966	100	0.799	Contact Map
3lnpA	2	0.6052	100	0.801	Contact Map
3be7A	5	0.5672	100	0.801	Contact Map
4c65A	6	0.5914	100	0.801	Contact Map
3sfwA	3	0.5862	100	0.805	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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