GREMLIN Database
YERA - Putative adenine deaminase YerA
UniProt: O34909 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 580 (552)
Sequences: 1540 (1148)
Seq/√Len: 48.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
30_L74_C4.9511.00
486_R505_E4.3051.00
486_R489_E4.1211.00
48_I79_I3.9471.00
472_A480_M3.9241.00
517_E521_D3.4761.00
35_V46_K3.3771.00
161_P164_V3.3751.00
476_N479_D3.3531.00
434_Y477_K3.2541.00
106_Y296_N3.2201.00
83_Y350_P3.2191.00
457_V498_E3.1451.00
296_N300_R3.0981.00
42_Q244_E3.0821.00
356_L361_I3.0821.00
74_C343_I3.0561.00
18_D23_K3.0491.00
345_E351_N2.9811.00
98_T101_E2.9761.00
180_M193_M2.8771.00
33_A79_I2.8741.00
435_L560_I2.8721.00
19_V56_V2.7571.00
280_Y284_G2.7561.00
436_T480_M2.7381.00
557_Y569_M2.7121.00
436_T472_A2.6271.00
461_V483_A2.5761.00
517_E525_K2.5691.00
470_I484_F2.5551.00
29_L68_E2.5041.00
80_V344_L2.4921.00
490_I505_E2.4621.00
79_I341_L2.4591.00
34_L45_K2.4511.00
281_T284_G2.4361.00
155_N562_P2.3751.00
479_D500_G2.3511.00
79_I343_I2.3451.00
450_I550_L2.3311.00
404_V451_K2.3181.00
404_V415_Y2.3081.00
33_A74_C2.3061.00
37_N40_V2.2991.00
393_M478_A2.2941.00
30_L343_I2.2871.00
182_G185_R2.2711.00
345_E353_V2.2691.00
276_D322_K2.2651.00
128_L171_H2.1951.00
135_K173_D2.1431.00
280_Y302_A2.1221.00
404_V413_E2.0721.00
291_K527_Q2.0631.00
413_E557_Y2.0571.00
277_H282_T2.0251.00
303_L350_P2.0181.00
36_L80_V1.9780.99
77_K353_V1.9770.99
482_L486_R1.9750.99
472_A484_F1.9690.99
496_L532_L1.9660.99
453_F473_I1.9640.99
39_Y332_V1.9630.99
132_N135_K1.9580.99
354_T361_I1.9290.99
463_S470_I1.9270.99
485_A488_K1.9170.99
567_D570_K1.9120.99
34_L43_W1.8950.99
427_S430_H1.8940.99
36_L43_W1.8390.99
299_I342_N1.8230.99
481_L485_A1.8070.99
313_Y350_P1.8060.99
277_H284_G1.8050.99
18_D24_L1.8050.99
145_S165_R1.7820.99
333_V341_L1.7780.99
346_D349_N1.7710.99
414_P574_L1.7410.99
35_V48_I1.7390.99
119_L127_A1.7320.99
77_K343_I1.7170.98
220_T245_L1.7090.98
504_H532_L1.7090.98
261_R305_E1.6750.98
108_T294_M1.6720.98
261_R301_I1.6670.98
128_L132_N1.6530.98
396_L484_F1.6530.98
140_Q330_L1.6450.98
122_S511_C1.6310.98
94_Y522_V1.6300.98
487_M495_V1.6280.98
279_F282_T1.6270.98
197_M207_I1.6250.98
313_Y317_S1.6240.98
490_I495_V1.6150.98
55_I341_L1.6070.98
482_L500_G1.6050.98
363_R366_G1.5990.98
72_I356_L1.5900.97
41_K311_D1.5860.97
27_T51_Y1.5830.97
155_N563_R1.5830.97
37_N44_L1.5790.97
343_I356_L1.5760.97
37_N42_Q1.5740.97
486_R490_I1.5630.97
19_V51_Y1.5540.97
275_Y282_T1.5450.97
15_A51_Y1.5310.97
21_D218_T1.5290.97
497_A502_I1.5250.97
32_N73_D1.5170.97
153_V566_F1.5140.97
301_I305_E1.5110.96
438_L484_F1.5100.96
387_L488_K1.4990.96
90_P141_Y1.4990.96
279_F284_G1.4840.96
243_L278_F1.4620.96
36_L313_Y1.4550.96
105_Q363_R1.4540.96
509_A516_S1.4510.96
140_Q358_K1.4490.96
338_L358_K1.4450.95
229_C323_Y1.4430.95
41_K314_N1.4350.95
354_T364_E1.4320.95
56_V224_L1.4240.95
170_E203_Q1.4230.95
280_Y295_T1.4190.95
393_M481_L1.4100.95
25_L69_I1.4030.95
28_L50_I1.3860.94
77_K345_E1.3820.94
558_I574_L1.3770.94
48_I333_V1.3740.94
140_Q357_S1.3720.94
432_E449_M1.3710.94
240_M244_E1.3630.94
102_Y519_Y1.3580.94
182_G190_D1.3570.94
553_T561_T1.3530.94
433_S475_K1.3490.93
391_M481_L1.3440.93
314_N318_F1.3430.93
144_W176_Q1.3390.93
277_H280_Y1.3350.93
15_A52_Q1.3150.93
26_P49_W1.3150.93
257_R410_V1.3140.92
299_I316_A1.2950.92
438_L463_S1.2920.92
125_K128_L1.2850.92
299_I303_L1.2830.92
248_Y279_F1.2780.91
463_S484_F1.2750.91
281_T324_Y1.2740.91
232_E252_R1.2730.91
301_I304_E1.2720.91
250_S281_T1.2710.91
487_M490_I1.2690.91
128_L167_Q1.2640.91
36_L310_I1.2630.91
275_Y284_G1.2550.91
457_V475_K1.2530.91
398_F449_M1.2490.90
307_V315_M1.2450.90
223_K247_Y1.2390.90
30_L50_I1.2370.90
50_I341_L1.2310.90
566_F573_V1.2230.89
41_K310_I1.2190.89
128_L168_W1.2150.89
166_K202_K1.2130.89
495_V505_E1.2120.89
180_M185_R1.2100.89
496_L536_R1.2090.89
15_A24_L1.2020.89
531_D535_E1.1950.88
155_N445_R1.1920.88
507_P525_K1.1910.88
68_E71_T1.1890.88
251_L264_L1.1880.88
248_Y322_K1.1820.88
465_T471_V1.1790.88
385_L491_G1.1760.88
135_K171_H1.1720.87
267_L315_M1.1670.87
253_N261_R1.1630.87
421_N424_E1.1580.87
510_L516_S1.1580.87
417_I451_K1.1540.87
385_L463_S1.1520.86
274_Y282_T1.1520.86
18_D189_G1.1510.86
124_K168_W1.1500.86
461_V472_A1.1490.86
39_Y337_R1.1480.86
98_T519_Y1.1480.86
515_S522_V1.1470.86
36_L78_Y1.1460.86
445_R562_P1.1450.86
344_L350_P1.1440.86
479_D482_L1.1420.86
131_L173_D1.1410.86
86_P281_T1.1360.86
341_L356_L1.1360.86
219_L241_R1.1350.86
486_R495_V1.1340.86
396_L403_G1.1330.86
474_G480_M1.1320.85
95_N510_L1.1310.85
521_D524_E1.1260.85
134_L173_D1.1200.85
144_W175_I1.1190.85
248_Y323_Y1.1150.85
439_D444_W1.1140.85
344_L352_P1.1100.84
396_L481_L1.1100.84
259_D409_A1.1080.84
428_F433_S1.1070.84
487_M491_G1.1060.84
43_W78_Y1.1050.84
295_T316_A1.1030.84
49_W59_G1.1010.84
19_V26_P1.0960.84
18_D21_D1.0920.83
134_L137_Q1.0870.83
103_V111_F1.0850.83
438_L446_V1.0840.83
471_V551_Q1.0810.83
44_L244_E1.0800.83
249_V266_E1.0790.83
518_A521_D1.0790.83
113_N143_W1.0700.82
111_F139_V1.0670.82
153_V573_V1.0630.82
50_I356_L1.0620.82
33_A343_I1.0620.82
105_Q139_V1.0570.81
236_G266_E1.0510.81
122_S381_G1.0510.81
274_Y284_G1.0480.81
250_S324_Y1.0460.81
383_V491_G1.0440.80
299_I317_S1.0430.80
229_C324_Y1.0420.80
43_W347_P1.0420.80
330_L338_L1.0410.80
303_L309_A1.0410.80
394_D397_Q1.0390.80
248_Y277_H1.0310.80
100_A138_P1.0300.80
504_H528_K1.0230.79
483_A497_A1.0220.79
83_Y342_N1.0220.79
332_V337_R1.0210.79
169_I205_K1.0200.79
436_T484_F1.0160.79
309_A312_A1.0160.79
140_Q338_L1.0140.78
314_N319_N1.0130.78
435_L473_I1.0100.78
80_V342_N1.0070.78
118_L126_K1.0040.78
32_N75_E1.0010.78
33_A341_L1.0000.77
28_L72_I1.0000.77
110_T142_F0.9980.77
184_P571_K0.9980.77
361_I364_E0.9970.77
29_L49_W0.9970.77
415_Y451_K0.9940.77
31_R71_T0.9940.77
145_S168_W0.9920.77
88_A99_L0.9890.77
212_P242_R0.9820.76
78_Y347_P0.9820.76
328_D338_L0.9800.76
259_D262_K0.9790.76
40_V244_E0.9760.76
279_F323_Y0.9740.76
396_L480_M0.9740.76
182_G193_M0.9730.76
154_L562_P0.9730.76
397_Q423_M0.9690.75
450_I453_F0.9680.75
116_L468_G0.9670.75
46_K58_V0.9650.75
414_P558_I0.9640.75
274_Y280_Y0.9600.75
124_K167_Q0.9590.74
29_L71_T0.9570.74
275_Y280_Y0.9570.74
307_V312_A0.9510.74
189_G194_L0.9510.74
438_L470_I0.9500.74
435_L550_L0.9490.74
185_R193_M0.9480.74
30_L356_L0.9470.74
435_L448_T0.9440.73
55_I58_V0.9440.73
473_I547_L0.9440.73
92_Q99_L0.9400.73
20_V221_K0.9390.73
236_G240_M0.9370.73
471_V560_I0.9330.72
38_P332_V0.9330.72
104_S139_V0.9310.72
277_H322_K0.9280.72
420_D425_Q0.9220.72
22_S217_K0.9210.71
116_L181_T0.9210.71
181_T554_H0.9210.71
35_V58_V0.9140.71
125_K380_G0.9130.71
462_S548_L0.9070.70
524_E528_K0.9070.70
255_S324_Y0.9060.70
195_H199_A0.9010.70
525_K528_K0.9010.70
130_I514_A0.9010.70
86_P320_I0.8990.70
299_I313_Y0.8990.70
127_A168_W0.8970.69
82_G109_T0.8970.69
142_F175_I0.8930.69
117_F466_T0.8920.69
186_L197_M0.8870.69
111_F141_Y0.8860.68
194_L197_M0.8850.68
127_A145_S0.8850.68
238_E241_R0.8840.68
79_I333_V0.8830.68
19_V24_L0.8820.68
303_L313_Y0.8820.68
86_P324_Y0.8810.68
482_L502_I0.8810.68
169_I199_A0.8800.68
99_L111_F0.8800.68
239_V266_E0.8790.68
31_R47_N0.8790.68
148_D185_R0.8790.68
91_F468_G0.8780.68
566_F571_K0.8770.68
118_L130_I0.8750.67
245_L335_P0.8750.67
406_M413_E0.8740.67
17_V189_G0.8730.67
216_D241_R0.8730.67
48_I58_V0.8720.67
91_F116_L0.8700.67
148_D181_T0.8670.67
117_F468_G0.8660.67
215_S241_R0.8610.66
28_L356_L0.8610.66
91_F552_S0.8570.66
461_V484_F0.8560.66
91_F117_F0.8550.66
229_C281_T0.8540.66
198_Q202_K0.8540.66
295_T298_L0.8540.66
97_Q133_E0.8520.65
206_R323_Y0.8500.65
166_K199_A0.8480.65
460_F533_L0.8470.65
391_M396_L0.8440.65
74_C79_I0.8430.65
560_I565_I0.8420.64
29_L47_N0.8360.64
498_E503_L0.8340.64
281_T316_A0.8340.64
457_V499_N0.8330.64
303_L346_D0.8310.63
103_V139_V0.8300.63
450_I473_I0.8280.63
433_S473_I0.8280.63
122_S126_K0.8260.63
49_W57_Y0.8260.63
318_F322_K0.8250.63
364_E367_C0.8240.63
381_G384_P0.8200.62
216_D219_L0.8180.62
277_H281_T0.8180.62
70_H360_T0.8180.62
464_F513_C0.8170.62
427_S431_D0.8160.62
234_M411_I0.8120.62
116_L149_L0.8110.62
129_T133_E0.8100.61
253_N301_I0.8100.61
36_L347_P0.8080.61
160_L165_R0.8070.61
482_L497_A0.8070.61
506_I522_V0.8060.61
169_I200_T0.8040.61
239_V249_V0.8010.61
169_I255_S0.8010.61
86_P250_S0.7980.60
476_N480_M0.7970.60
166_K203_Q0.7970.60
458_Q479_D0.7970.60
417_I449_M0.7960.60
37_N332_V0.7940.60
88_A92_Q0.7930.60
461_V487_M0.7930.60
250_S279_F0.7920.60
346_D351_N0.7890.59
537_G543_P0.7880.59
100_A137_Q0.7880.59
108_T545_Y0.7870.59
99_L103_V0.7870.59
23_K241_R0.7840.59
142_F330_L0.7810.59
165_R169_I0.7810.59
406_M409_A0.7800.59
417_I427_S0.7790.58
117_F552_S0.7740.58
257_R549_F0.7730.58
156_E467_T0.7720.58
112_V324_Y0.7720.58
532_L535_E0.7720.58
486_R502_I0.7700.58
533_L542_D0.7700.58
353_V365_N0.7680.57
509_A515_S0.7670.57
363_R368_D0.7670.57
261_R304_E0.7650.57
468_G552_S0.7640.57
99_L294_M0.7630.57
396_L402_M0.7610.57
134_L141_Y0.7580.56
91_F181_T0.7570.56
503_L536_R0.7570.56
43_W310_I0.7570.56
274_Y277_H0.7560.56
34_L78_Y0.7550.56
273_R284_G0.7550.56
70_H361_I0.7530.56
215_S251_L0.7480.55
147_Y177_G0.7480.55
131_L143_W0.7460.55
35_V341_L0.7460.55
147_Y468_G0.7450.55
137_Q141_Y0.7450.55
145_S174_V0.7440.55
480_M484_F0.7420.55
16_Q56_V0.7410.55
521_D525_K0.7410.55
465_T551_Q0.7410.55
84_I112_V0.7400.55
106_Y352_P0.7370.54
431_D454_A0.7340.54
264_L307_V0.7320.54
119_L230_D0.7320.54
275_Y311_D0.7310.54
27_T69_I0.7290.53
181_T468_G0.7270.53
147_Y181_T0.7270.53
378_H381_G0.7270.53
116_L552_S0.7260.53
427_S449_M0.7260.53
352_P355_V0.7260.53
460_F496_L0.7240.53
426_L477_K0.7240.53
467_T553_T0.7240.53
167_Q170_E0.7230.53
410_V555_L0.7210.53
84_I321_A0.7210.53
398_F402_M0.7190.52
276_D314_N0.7170.52
57_Y61_E0.7140.52
38_P314_N0.7130.52
249_V278_F0.7120.52
117_F121_Q0.7120.52
165_R199_A0.7120.52
90_P96_P0.7110.52
390_D488_K0.7100.52
94_Y519_Y0.7080.51
326_M330_L0.7050.51
192_L196_C0.7040.51
274_Y278_F0.7040.51
191_D195_H0.7040.51
424_E427_S0.7030.51
91_F284_G0.7010.51
92_Q103_V0.7000.50
154_L553_T0.6990.50
164_V167_Q0.6980.50
393_M396_L0.6980.50
422_S426_L0.6980.50
263_I266_E0.6970.50
207_I227_A0.6970.50
506_I525_K0.6940.50
70_H364_E0.6940.50
91_F147_Y0.6930.50
311_D314_N0.6920.50
417_I424_E0.6920.50
479_D499_N0.6910.50
120_L468_G0.6900.49
273_R282_T0.6890.49
93_I464_F0.6880.49
16_Q19_V0.6880.49
211_F242_R0.6880.49
23_K189_G0.6870.49
378_H385_L0.6870.49
396_L436_T0.6850.49
420_D426_L0.6850.49
422_S427_S0.6830.49
72_I361_I0.6830.49
38_P310_I0.6820.49
334_G337_R0.6800.48
294_M545_Y0.6790.48
223_K245_L0.6770.48
292_G297_E0.6750.48
431_D452_G0.6750.48
388_S488_K0.6750.48
463_S490_I0.6740.48
229_C250_S0.6730.48
36_L344_L0.6720.48
251_L280_Y0.6710.48
119_L168_W0.6690.47
148_D554_H0.6680.47
24_L51_Y0.6670.47
275_Y315_M0.6650.47
131_L171_H0.6650.47
276_D319_N0.6650.47
165_R197_M0.6650.47
120_L157_D0.6640.47
116_L554_H0.6630.47
400_M403_G0.6620.47
400_M424_E0.6590.46
242_R249_V0.6590.46
285_A289_F0.6590.46
82_G340_S0.6580.46
116_L466_T0.6580.46
428_F475_K0.6570.46
453_F462_S0.6570.46
149_L181_T0.6560.46
155_N444_W0.6550.46
313_Y347_P0.6550.46
262_K265_Q0.6540.46
187_V221_K0.6540.46
219_L245_L0.6540.46
427_S432_E0.6540.46
237_D241_R0.6510.46
447_N560_I0.6490.45
113_N178_G0.6480.45
280_Y316_A0.6470.45
343_I353_V0.6470.45
275_Y281_T0.6460.45
308_P311_D0.6460.45
55_I333_V0.6460.45
533_L536_R0.6460.45
91_F554_H0.6440.45
563_R573_V0.6400.44
360_T367_C0.6400.44
116_L120_L0.6390.44
86_P465_T0.6390.44
489_E505_E0.6380.44
233_A238_E0.6370.44
219_L223_K0.6370.44
84_I320_I0.6370.44
99_L559_R0.6350.44
433_S450_I0.6350.44
42_Q273_R0.6350.44
313_Y344_L0.6340.44
82_G317_S0.6330.44
251_L267_L0.6330.44
417_I430_H0.6330.44
138_P560_I0.6320.44
83_Y317_S0.6290.43
303_L345_E0.6280.43
100_A515_S0.6260.43
71_T75_E0.6260.43
72_I354_T0.6250.43
327_D337_R0.6240.43
232_E254_S0.6230.43
88_A294_M0.6220.43
79_I374_K0.6220.43
314_N317_S0.6190.42
110_T328_D0.6190.42
116_L147_Y0.6190.42
148_D467_T0.6160.42
192_L195_H0.6160.42
499_N502_I0.6160.42
151_T553_T0.6150.42
30_L341_L0.6150.42
120_L181_T0.6140.42
117_F149_L0.6140.42
30_L79_I0.6130.42
110_T140_Q0.6130.42
120_L149_L0.6130.42
175_I186_L0.6130.42
250_S323_Y0.6120.42
437_M562_P0.6100.41
464_F494_I0.6100.41
163_D195_H0.6080.41
108_T463_S0.6080.41
120_L552_S0.6070.41
117_F181_T0.6070.41
199_A203_Q0.6060.41
346_D356_L0.6060.41
528_K532_L0.6060.41
279_F320_I0.6050.41
119_L160_L0.6040.41
205_K510_L0.6040.41
515_S518_A0.6040.41
303_L352_P0.6040.41
431_D475_K0.6040.41
213_G411_I0.6030.41
37_N337_R0.6030.41
309_A313_Y0.6030.41
265_Q268_H0.6030.41
149_L552_S0.6030.41
530_R542_D0.6010.41
121_Q466_T0.6000.40
116_L148_D0.6000.40
45_K75_E0.6000.40
124_K164_V0.5990.40
151_T562_P0.5990.40
236_G239_V0.5990.40
149_L468_G0.5980.40
96_P377_W0.5980.40
51_Y56_V0.5970.40
390_D393_M0.5960.40
108_T212_P0.5950.40
80_V83_Y0.5940.40
100_A134_L0.5930.40
121_Q441_H0.5930.40
193_M196_C0.5920.40
379_K383_V0.5920.40
208_E229_C0.5900.40
179_E210_H0.5890.39
342_N352_P0.5890.39
476_N499_N0.5880.39
213_G235_T0.5880.39
162_F195_H0.5880.39
168_W171_H0.5870.39
103_V289_F0.5870.39
121_Q157_D0.5860.39
396_L400_M0.5860.39
49_W61_E0.5860.39
243_L249_V0.5850.39
118_L511_C0.5840.39
317_S321_A0.5840.39
421_N478_A0.5830.39
30_L152_E0.5810.39
515_S525_K0.5810.39
236_G265_Q0.5800.39
251_L301_I0.5790.38
77_K344_L0.5790.38
121_Q149_L0.5780.38
509_A517_E0.5770.38
211_F238_E0.5760.38
196_C549_F0.5760.38
388_S531_D0.5760.38
211_F214_A0.5750.38
280_Y298_L0.5740.38
126_K511_C0.5740.38
85_E294_M0.5730.38
264_L267_L0.5720.38
533_L538_Y0.5720.38
133_E136_K0.5720.38
414_P567_D0.5710.38
181_T552_S0.5700.38
80_V333_V0.5700.38
303_L318_F0.5690.37
233_A259_D0.5690.37
120_L469_D0.5680.37
92_Q229_C0.5670.37
103_V108_T0.5660.37
49_W68_E0.5660.37
390_D398_F0.5660.37
238_E437_M0.5660.37
438_L472_A0.5650.37
417_I432_E0.5640.37
50_I299_I0.5630.37
426_L449_M0.5620.37
378_H384_P0.5620.37
104_S357_S0.5620.37
83_Y307_V0.5600.37
117_F147_Y0.5600.37
265_Q305_E0.5600.37
534_T572_T0.5600.37
388_S443_K0.5590.37
83_Y352_P0.5580.36
120_L150_Q0.5580.36
244_E499_N0.5570.36
140_Q340_S0.5560.36
21_D187_V0.5550.36
220_T296_N0.5550.36
448_T560_I0.5540.36
254_S434_Y0.5530.36
117_F120_L0.5530.36
17_V194_L0.5520.36
452_G561_T0.5510.36
83_Y344_L0.5510.36
410_V559_R0.5510.36
256_I546_T0.5510.36
496_L544_I0.5500.36
468_G554_H0.5490.36
455_S536_R0.5490.36
242_R424_E0.5490.36
70_H354_T0.5480.36
344_L353_V0.5480.36
544_I548_L0.5470.35
304_E349_N0.5470.35
91_F149_L0.5460.35
239_V317_S0.5460.35
161_P192_L0.5460.35
16_Q52_Q0.5450.35
156_E165_R0.5450.35
299_I350_P0.5450.35
220_T335_P0.5440.35
126_K130_I0.5440.35
129_T132_N0.5430.35
228_D328_D0.5420.35
441_H444_W0.5420.35
253_N258_P0.5410.35
92_Q469_D0.5400.35
463_S483_A0.5400.35
137_Q370_K0.5400.35
37_N245_L0.5400.35
181_T466_T0.5390.35
50_I343_I0.5390.35
88_A282_T0.5380.35
496_L529_L0.5380.35
264_L501_N0.5370.35
50_I235_T0.5360.34
297_E300_R0.5360.34
174_V205_K0.5350.34
317_S320_I0.5350.34
241_R245_L0.5350.34
453_F543_P0.5340.34
93_I508_L0.5340.34
157_D468_G0.5330.34
84_I110_T0.5330.34
48_I358_K0.5320.34
99_L242_R0.5320.34
21_D221_K0.5320.34
149_L466_T0.5310.34
37_N43_W0.5310.34
431_D451_K0.5310.34
102_Y259_D0.5310.34
150_Q468_G0.5310.34
144_W208_E0.5300.34
399_S501_N0.5300.34
26_P29_L0.5290.34
466_T552_S0.5270.34
124_K128_L0.5270.34
198_Q201_K0.5270.34
29_L137_Q0.5260.34
310_I313_Y0.5260.34
441_H552_S0.5260.34
398_F403_G0.5250.33
426_L432_E0.5250.33
478_A500_G0.5240.33
382_L516_S0.5240.33
116_L121_Q0.5230.33
557_Y567_D0.5230.33
23_K187_V0.5230.33
54_R327_D0.5230.33
148_D182_G0.5220.33
147_Y552_S0.5220.33
243_L307_V0.5220.33
380_G384_P0.5220.33
47_N68_E0.5220.33
182_G449_M0.5220.33
145_S169_I0.5210.33
481_L488_K0.5200.33
77_K356_L0.5200.33
91_F466_T0.5200.33
550_L559_R0.5190.33
235_T238_E0.5190.33
178_G409_A0.5190.33
16_Q54_R0.5180.33
208_E549_F0.5180.33
57_Y220_T0.5180.33
213_G257_R0.5170.33
501_N524_E0.5170.33
420_D528_K0.5170.33
300_R352_P0.5160.33
436_T481_L0.5150.33
469_D552_S0.5140.32
335_P558_I0.5140.32
478_A482_L0.5130.32
80_V313_Y0.5130.32
49_W220_T0.5120.32
212_P545_Y0.5120.32
94_Y102_Y0.5120.32
91_F148_D0.5120.32
229_C249_V0.5120.32
420_D489_E0.5100.32
284_G468_G0.5100.32
47_N61_E0.5100.32
243_L263_I0.5100.32
36_L350_P0.5090.32
468_G513_C0.5090.32
432_E448_T0.5090.32
479_D502_I0.5080.32
229_C566_F0.5080.32
223_K335_P0.5070.32
243_L266_E0.5070.32
111_F496_L0.5070.32
396_L401_P0.5060.32
212_P294_M0.5050.32
303_L348_L0.5050.32
144_W178_G0.5050.32
91_F120_L0.5050.32
237_D499_N0.5040.32
367_C478_A0.5040.32
163_D531_D0.5040.32
178_G256_I0.5030.31
157_D441_H0.5030.31
304_E410_V0.5020.31
37_N357_S0.5020.31
266_E278_F0.5020.31
410_V549_F0.5020.31
256_I259_D0.5020.31
559_R565_I0.5010.31
381_G386_E0.5010.31
43_W313_Y0.5000.31
195_H536_R0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3nqbA 2 0.981 100 0.334 Contact Map
2icsA 1 0.5552 100 0.793 Contact Map
2vunA 3 0.5828 100 0.796 Contact Map
2ogjA 4 0.5741 100 0.797 Contact Map
3mtwA 5 0.5724 100 0.799 Contact Map
4whbE 3 0.5966 100 0.799 Contact Map
3lnpA 2 0.6052 100 0.801 Contact Map
3be7A 5 0.5672 100 0.801 Contact Map
4c65A 6 0.5914 100 0.801 Contact Map
3sfwA 3 0.5862 100 0.805 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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