EZRA - BACSU - GREMLIN Contacts

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EZRA - Septation ring formation regulator EzrA

UniProt:	O34894	Sequences: MEFVIGLLIVLLALFAAGYFFRKKIYAEIDRLESWKIEILNRSIVEEMSKIKHLKMTGQTEEFFEKWREEWDEIVTAHMPKVEELLYDAEENADKYRFKKANQVLVHIDDLLTAAESSIEKILREISDLVTSEEKSREEIEQVRERYSKSRKNLLAYSHLYGELYDSLEKDLDEIWSGIKQFEEETEGGNYITARKVLLEQDRNLERLQSYIDDVPKLLADCKQTVPGQIAKLKDGYGEMKEKGYKLEHIQLDKELENLSNQLKRAEHVLMTELDIDEASAILQLIDENIQSVYQQLEGEVEAGQSVLSKMPELIIAYDKLKEEKEHTKAETELVKESYRLTAGELGKQQAFEKRLDEIGKLLSSVKDKLDAEHVAYSLLVEEVASIEKQIEEVKKEHAEYRENLQALRKEELQARETLSNLKKTISETARLLKTSNIPGIPSHIQEMLENAHHHIQETVNQLNELPLNMEEAGAHLKQAEDIVNRASRESEELVEQVILIEKIIQFGNRFRSQNHILSEQLKEAERRFYAFDYDDSYEIAAAAVEKAAPGAVEKIKADISA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	562 (453)
Sequences:	10215 (9011)
Seq/√Len:	423.4

BACSU - EZRA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
463_L	466_L	2.788	1.00
398_H	401_Y	2.663	1.00
205_L	208_L	2.647	1.00
426_I	429_T	2.498	1.00
112_L	115_A	2.454	1.00
405_L	408_L	2.418	1.00
442_P	445_I	2.415	1.00
290_I	293_V	2.337	1.00
311_M	314_L	2.326	1.00
256_L	259_L	2.308	1.00
391_I	394_V	2.290	1.00
64_F	67_W	2.273	1.00
491_S	494_L	2.237	1.00
283_L	286_I	2.186	1.00
449_L	452_A	2.163	1.00
477_L	480_A	2.145	1.00
198_L	201_Q	2.121	1.00
363_L	366_V	2.115	1.00
470_M	473_A	2.066	1.00
377_Y	380_L	2.045	1.00
237_Y	240_M	2.034	1.00
356_L	359_I	2.032	1.00
212_I	215_V	2.029	1.00
456_I	459_T	2.029	1.00
384_V	387_I	1.963	1.00
325_K	328_T	1.961	1.00
412_E	415_A	1.946	1.00
484_V	487_A	1.938	1.00
172_L	175_I	1.922	1.00
263_L	266_A	1.921	1.00
105_L	108_I	1.916	1.00
297_L	300_E	1.909	1.00
262_Q	267_E	1.908	1.00
119_I	122_I	1.876	1.00
111_L	116_E	1.847	1.00
339_Y	342_T	1.843	1.00
472_E	476_H	1.793	1.00
79_M	82_V	1.789	1.00
147_Y	150_S	1.751	1.00
126_I	129_L	1.737	1.00
139_E	142_Q	1.734	1.00
300_E	304_G	1.699	1.00
179_I	182_F	1.699	1.00
191_Y	194_A	1.696	1.00
140_I	143_V	1.677	1.00
358_E	362_L	1.675	1.00
332_T	335_V	1.674	1.00
276_I	279_A	1.659	1.00
448_M	451_N	1.653	1.00
57_T	60_T	1.651	1.00
71_W	74_I	1.632	1.00
391_I	395_K	1.596	1.00
349_Q	352_F	1.589	1.00
419_L	422_L	1.587	1.00
332_T	336_K	1.570	1.00
486_R	490_E	1.545	1.00
287_D	291_Q	1.542	1.00
125_E	130_V	1.536	1.00
498_V	501_I	1.530	1.00
480_A	484_V	1.526	1.00
195_R	199_L	1.502	1.00
285_L	289_N	1.494	1.00
383_E	388_E	1.494	1.00
178_G	183_E	1.485	1.00
376_A	379_L	1.482	1.00
229_Q	232_K	1.476	1.00
393_E	397_E	1.475	1.00
255_E	260_S	1.475	1.00
238_G	242_E	1.474	1.00
481_E	485_N	1.472	1.00
197_V	202_D	1.468	1.00
360_G	364_S	1.468	1.00
244_G	247_L	1.463	1.00
355_R	360_G	1.463	1.00
310_K	315_I	1.461	1.00
137_R	141_E	1.457	1.00
254_K	258_N	1.446	1.00
98_F	101_A	1.440	1.00
451_N	455_H	1.440	1.00
86_L	89_A	1.437	1.00
352_F	362_L	1.431	1.00
365_S	369_K	1.430	1.00
85_L	90_E	1.429	1.00
368_D	372_A	1.427	1.00
219_L	222_C	1.426	1.00
430_A	434_K	1.422	1.00
490_E	495_V	1.422	1.00
318_Y	321_L	1.420	1.00
116_E	120_E	1.417	1.00
341_L	345_E	1.404	1.00
353_E	357_D	1.401	1.00
133_E	136_S	1.397	1.00
282_I	287_D	1.396	1.00
231_A	234_K	1.388	1.00
289_N	292_S	1.381	1.00
446_Q	450_E	1.370	1.00
489_R	493_E	1.366	1.00
351_A	355_R	1.364	1.00
457_Q	461_N	1.364	1.00
396_K	400_E	1.361	1.00
271_M	274_L	1.360	1.00
118_S	123_L	1.359	1.00
362_L	366_V	1.359	1.00
478_K	481_E	1.358	1.00
138_E	142_Q	1.356	1.00
196_K	200_E	1.350	1.00
342_T	345_E	1.344	1.00
149_K	153_N	1.344	1.00
324_E	329_K	1.334	1.00
139_E	144_R	1.331	1.00
170_K	174_E	1.328	1.00
425_T	430_A	1.325	1.00
284_Q	288_E	1.322	1.00
88_D	92_N	1.319	1.00
338_S	343_A	1.316	1.00
85_L	89_A	1.314	1.00
209_Q	213_D	1.312	1.00
229_Q	234_K	1.308	1.00
234_K	238_G	1.301	1.00
373_E	377_Y	1.297	1.00
258_N	262_Q	1.297	1.00
123_L	127_S	1.294	1.00
301_V	305_Q	1.293	1.00
289_N	294_Y	1.292	1.00
462_Q	467_P	1.287	1.00
362_L	365_S	1.281	1.00
260_S	264_K	1.280	1.00
165_Y	168_L	1.278	1.00
109_D	113_T	1.276	1.00
251_Q	255_E	1.275	1.00
147_Y	151_R	1.272	1.00
142_Q	146_R	1.270	1.00
204_N	209_Q	1.269	1.00
237_Y	241_K	1.262	1.00
239_E	243_K	1.255	1.00
395_K	399_A	1.249	1.00
57_T	61_E	1.247	1.00
483_I	486_R	1.242	1.00
83_E	87_Y	1.239	1.00
107_H	111_L	1.239	1.00
411_E	414_Q	1.238	1.00
156_A	160_L	1.237	1.00
390_Q	395_K	1.235	1.00
381_V	385_A	1.233	1.00
100_K	104_V	1.231	1.00
110_D	114_A	1.226	1.00
70_E	75_V	1.216	1.00
323_E	327_H	1.215	1.00
199_L	202_D	1.214	1.00
474_G	478_K	1.213	1.00
441_I	444_H	1.209	1.00
106_V	109_D	1.209	1.00
304_G	307_V	1.208	1.00
171_D	174_E	1.200	1.00
114_A	118_S	1.196	1.00
278_E	282_I	1.195	1.00
327_H	331_E	1.191	1.00
385_A	389_K	1.190	1.00
158_S	162_G	1.189	1.00
338_S	342_T	1.188	1.00
367_K	371_D	1.187	1.00
484_V	488_S	1.186	1.00
427_S	430_A	1.182	1.00
417_E	421_N	1.182	1.00
429_T	432_L	1.181	1.00
87_Y	90_E	1.178	1.00
317_A	320_K	1.170	1.00
418_T	423_K	1.165	1.00
231_A	235_D	1.165	1.00
210_S	214_D	1.164	1.00
180_K	183_E	1.164	1.00
183_E	187_E	1.162	1.00
445_I	448_M	1.161	1.00
143_V	147_Y	1.161	1.00
399_A	402_R	1.159	1.00
469_N	474_G	1.159	1.00
448_M	453_H	1.159	1.00
414_Q	418_T	1.157	1.00
146_R	151_R	1.152	1.00
115_A	119_I	1.151	1.00
261_N	265_R	1.150	1.00
392_E	395_K	1.150	1.00
213_D	216_P	1.149	1.00
298_E	302_E	1.148	1.00
362_L	367_K	1.143	1.00
65_E	68_R	1.141	1.00
112_L	116_E	1.140	1.00
298_E	301_V	1.140	1.00
262_Q	266_A	1.139	1.00
59_Q	63_F	1.136	1.00
340_R	343_A	1.135	1.00
211_Y	214_D	1.132	1.00
108_I	112_L	1.131	1.00
390_Q	393_E	1.121	1.00
401_Y	405_L	1.121	1.00
377_Y	381_V	1.119	1.00
385_A	388_E	1.119	1.00
104_V	109_D	1.118	1.00
290_I	294_Y	1.117	1.00
404_N	409_R	1.116	1.00
386_S	390_Q	1.115	1.00
403_E	406_Q	1.115	1.00
357_D	360_G	1.114	1.00
118_S	121_K	1.111	1.00
458_E	462_Q	1.109	1.00
312_P	315_I	1.109	1.00
364_S	367_K	1.106	1.00
220_A	223_K	1.101	1.00
172_L	176_W	1.101	1.00
379_L	383_E	1.100	1.00
475_A	479_Q	1.100	1.00
439_P	442_P	1.100	1.00
182_F	185_E	1.095	1.00
485_N	488_S	1.095	1.00
384_V	388_E	1.094	1.00
193_T	197_V	1.094	1.00
450_E	453_H	1.093	1.00
376_A	381_V	1.093	1.00
225_T	229_Q	1.090	1.00
228_G	232_K	1.090	1.00
61_E	65_E	1.085	1.00
218_L	221_D	1.084	1.00
428_E	432_L	1.083	1.00
457_Q	460_V	1.076	1.00
199_L	203_R	1.074	1.00
253_D	257_E	1.073	1.00
310_K	313_E	1.073	1.00
415_A	419_L	1.071	1.00
291_Q	294_Y	1.070	1.00
400_E	404_N	1.070	1.00
311_M	315_I	1.069	1.00
490_E	493_E	1.067	1.00
211_Y	216_P	1.064	1.00
369_K	372_A	1.064	1.00
121_K	125_E	1.063	1.00
127_S	131_T	1.062	1.00
129_L	133_E	1.062	1.00
141_E	144_R	1.060	1.00
479_Q	483_I	1.059	1.00
315_I	319_D	1.059	1.00
476_H	479_Q	1.059	1.00
124_R	128_D	1.057	1.00
63_F	68_R	1.057	1.00
144_R	148_S	1.055	1.00
359_I	363_L	1.055	1.00
90_E	94_D	1.054	1.00
81_K	85_L	1.052	1.00
455_H	458_E	1.051	1.00
113_T	116_E	1.050	1.00
72_D	76_T	1.050	1.00
423_K	427_S	1.048	1.00
208_L	215_V	1.047	1.00
226_V	229_Q	1.047	1.00
334_L	338_S	1.046	1.00
493_E	497_Q	1.046	1.00
275_D	280_S	1.045	1.00
304_G	308_L	1.045	1.00
450_E	454_H	1.044	1.00
478_K	482_D	1.044	1.00
280_S	284_Q	1.043	1.00
99_K	103_Q	1.043	1.00
494_L	498_V	1.043	1.00
293_V	300_E	1.041	1.00
176_W	180_K	1.040	1.00
87_Y	91_E	1.040	1.00
171_D	176_W	1.039	1.00
444_H	448_M	1.039	1.00
403_E	407_A	1.038	1.00
180_K	184_E	1.033	1.00
453_H	457_Q	1.032	1.00
184_E	187_E	1.032	1.00
363_L	367_K	1.032	1.00
491_S	495_V	1.031	1.00
462_Q	465_E	1.028	1.00
238_G	241_K	1.028	1.00
227_P	231_A	1.028	1.00
325_K	329_K	1.027	1.00
215_V	219_L	1.027	1.00
321_L	325_K	1.024	1.00
264_K	268_H	1.023	1.00
437_N	441_I	1.021	1.00
330_A	334_L	1.020	1.00
455_H	460_V	1.018	1.00
485_N	489_R	1.016	1.00
184_E	188_G	1.016	1.00
106_V	110_D	1.015	1.00
160_L	164_L	1.005	1.00
303_A	306_S	1.004	1.00
476_H	481_E	1.004	1.00
66_K	70_E	1.003	1.00
218_L	223_K	0.997	1.00
326_E	329_K	0.996	1.00
354_K	358_E	0.996	1.00
111_L	114_A	0.994	1.00
324_E	327_H	0.992	1.00
331_E	336_K	0.992	1.00
296_Q	301_V	0.992	1.00
439_P	443_S	0.990	1.00
190_N	193_T	0.987	1.00
410_K	414_Q	0.984	1.00
281_A	285_L	0.983	1.00
292_S	296_Q	0.981	1.00
419_L	423_K	0.975	1.00
82_V	85_L	0.975	1.00
103_Q	107_H	0.974	1.00
492_E	495_V	0.973	1.00
206_E	209_Q	0.971	1.00
145_E	149_K	0.970	1.00
463_L	467_P	0.969	1.00
175_I	179_I	0.967	1.00
62_E	66_K	0.966	1.00
445_I	452_A	0.964	1.00
245_Y	248_E	0.962	1.00
495_V	499_I	0.962	1.00
259_L	262_Q	0.961	1.00
295_Q	299_G	0.961	1.00
420_S	424_K	0.961	1.00
300_E	303_A	0.959	1.00
355_R	358_E	0.952	1.00
456_I	460_V	0.952	1.00
210_S	213_D	0.951	1.00
296_Q	299_G	0.950	1.00
173_D	176_W	0.949	1.00
406_Q	409_R	0.949	1.00
197_V	201_Q	0.947	1.00
288_E	292_S	0.947	1.00
235_D	239_E	0.946	1.00
350_Q	354_K	0.946	1.00
192_I	195_R	0.942	1.00
113_T	117_S	0.941	1.00
322_K	326_E	0.941	1.00
317_A	322_K	0.939	1.00
257_E	261_N	0.938	1.00
324_E	328_T	0.933	1.00
469_N	472_E	0.931	1.00
204_N	207_R	0.930	1.00
86_L	90_E	0.929	1.00
282_I	285_L	0.926	1.00
115_A	122_I	0.926	1.00
80_P	83_E	0.925	1.00
442_P	446_Q	0.923	1.00
411_E	416_R	0.922	1.00
466_L	470_M	0.921	1.00
146_R	150_S	0.920	1.00
441_I	446_Q	0.918	1.00
157_Y	161_Y	0.917	1.00
488_S	492_E	0.917	1.00
441_I	445_I	0.916	1.00
177_S	181_Q	0.914	1.00
413_L	417_E	0.913	1.00
373_E	376_A	0.909	1.00
328_T	332_T	0.909	1.00
350_Q	353_E	0.909	1.00
169_E	173_D	0.908	1.00
251_Q	254_K	0.908	1.00
374_H	378_S	0.908	1.00
404_N	407_A	0.908	1.00
283_L	287_D	0.904	1.00
382_E	386_S	0.903	1.00
214_D	218_L	0.903	1.00
349_Q	353_E	0.901	1.00
173_D	177_S	0.901	1.00
397_E	400_E	0.900	1.00
244_G	248_E	0.899	1.00
205_L	209_Q	0.899	1.00
85_L	88_D	0.899	1.00
399_A	403_E	0.896	1.00
425_T	428_E	0.896	1.00
128_D	132_S	0.895	1.00
467_P	471_E	0.894	1.00
443_S	447_E	0.894	1.00
197_V	200_E	0.894	1.00
80_P	84_E	0.891	1.00
402_R	406_Q	0.886	1.00
500_L	503_K	0.886	1.00
462_Q	466_L	0.885	1.00
277_D	281_A	0.884	1.00
357_D	361_K	0.882	1.00
295_Q	298_E	0.881	1.00
368_D	371_D	0.879	1.00
157_Y	160_L	0.879	1.00
329_K	333_E	0.878	1.00
387_I	391_I	0.877	1.00
65_E	69_E	0.876	1.00
127_S	130_V	0.876	1.00
56_M	60_T	0.873	1.00
71_W	75_V	0.872	1.00
198_L	202_D	0.872	1.00
196_K	199_L	0.870	1.00
194_A	198_L	0.869	1.00
120_E	123_L	0.868	1.00
471_E	474_G	0.868	1.00
326_E	330_A	0.868	1.00
207_R	211_Y	0.867	1.00
108_I	115_A	0.866	1.00
125_E	128_D	0.865	1.00
447_E	451_N	0.863	1.00
58_G	62_E	0.860	1.00
115_A	118_S	0.860	1.00
195_R	198_L	0.859	1.00
213_D	217_K	0.857	1.00
339_Y	343_A	0.851	1.00
302_E	306_S	0.851	1.00
389_K	393_E	0.849	1.00
185_E	188_G	0.848	1.00
159_H	163_E	0.844	1.00
445_I	449_L	0.844	1.00
164_L	167_S	0.843	1.00
219_L	223_K	0.843	1.00
230_I	237_Y	0.842	1.00
232_K	236_G	0.842	1.00
496_E	499_I	0.841	1.00
264_K	267_E	0.836	1.00
136_S	140_I	0.835	1.00
162_G	166_D	0.835	1.00
378_S	381_V	0.834	1.00
105_L	109_D	0.832	1.00
203_R	207_R	0.832	1.00
438_I	441_I	0.831	1.00
309_S	313_E	0.829	1.00
316_I	320_K	0.827	1.00
511_F	514_Q	0.825	1.00
230_I	233_L	0.824	1.00
392_E	396_K	0.823	1.00
69_E	73_E	0.821	1.00
148_S	151_R	0.821	1.00
55_K	59_Q	0.820	1.00
281_A	284_Q	0.818	1.00
287_D	290_I	0.817	1.00
208_L	212_I	0.817	1.00
475_A	478_K	0.816	1.00
482_D	486_R	0.814	1.00
192_I	196_K	0.812	1.00
95_K	99_K	0.811	1.00
286_I	290_I	0.810	1.00
140_I	144_R	0.809	1.00
135_K	139_E	0.807	1.00
117_S	120_E	0.805	1.00
440_G	444_H	0.805	1.00
89_A	92_N	0.802	1.00
208_L	211_Y	0.800	1.00
454_H	458_E	0.799	1.00
420_S	423_K	0.798	1.00
122_I	126_I	0.798	1.00
320_K	324_E	0.797	1.00
200_E	204_N	0.796	1.00
464_N	467_P	0.795	1.00
99_K	102_N	0.795	1.00
155_L	158_S	0.794	1.00
60_T	64_F	0.793	1.00
236_G	239_E	0.793	1.00
252_L	262_Q	0.792	1.00
299_G	303_A	0.788	1.00
359_I	362_L	0.786	1.00
483_I	488_S	0.785	1.00
58_G	61_E	0.778	1.00
229_Q	233_L	0.778	1.00
177_S	180_K	0.777	1.00
276_I	280_S	0.775	1.00
255_E	258_N	0.775	1.00
263_L	267_E	0.773	1.00
331_E	334_L	0.771	1.00
366_V	370_L	0.771	1.00
216_P	220_A	0.769	1.00
124_R	127_S	0.769	1.00
262_Q	265_R	0.767	1.00
63_F	66_K	0.767	1.00
119_I	123_L	0.766	1.00
308_L	312_P	0.766	1.00
230_I	234_K	0.765	1.00
332_T	339_Y	0.764	1.00
265_R	269_V	0.762	1.00
167_S	171_D	0.762	1.00
178_G	181_Q	0.762	1.00
337_E	341_L	0.761	1.00
279_A	282_I	0.760	1.00
202_D	206_E	0.757	1.00
511_F	515_N	0.755	1.00
190_N	194_A	0.754	1.00
194_A	197_V	0.753	1.00
70_E	73_E	0.751	1.00
163_E	167_S	0.750	1.00
174_E	178_G	0.750	1.00
443_S	446_Q	0.749	1.00
370_L	373_E	0.743	1.00
171_D	175_I	0.741	1.00
313_E	317_A	0.741	1.00
410_K	413_L	0.740	1.00
312_P	316_I	0.734	1.00
310_K	314_L	0.732	1.00
201_Q	205_L	0.728	1.00
418_T	421_N	0.727	1.00
169_E	172_L	0.724	1.00
130_V	134_E	0.723	1.00
56_M	61_E	0.721	1.00
425_T	429_T	0.719	1.00
179_I	183_E	0.719	1.00
407_A	411_E	0.719	1.00
59_Q	62_E	0.716	1.00
416_R	420_S	0.715	1.00
198_L	205_L	0.715	1.00
56_M	59_Q	0.712	1.00
388_E	392_E	0.709	1.00
448_M	452_A	0.709	1.00
217_K	221_D	0.709	1.00
160_L	163_E	0.708	1.00
429_T	433_L	0.706	1.00
305_Q	308_L	0.706	1.00
141_E	145_E	0.705	1.00
111_L	115_A	0.704	1.00
261_N	264_K	0.704	1.00
257_E	260_S	0.702	1.00
284_Q	287_D	0.701	1.00
340_R	344_G	0.700	1.00
191_Y	195_R	0.700	1.00
236_G	241_K	0.699	1.00
421_N	425_T	0.697	1.00
412_E	416_R	0.697	1.00
97_R	100_K	0.691	1.00
148_S	152_K	0.690	1.00
250_I	254_K	0.689	1.00
427_S	431_R	0.689	1.00
492_E	496_E	0.688	1.00
364_S	368_D	0.686	1.00
130_V	133_E	0.685	1.00
299_G	302_E	0.683	1.00
72_D	75_V	0.678	1.00
484_V	494_L	0.675	1.00
79_M	83_E	0.675	1.00
449_L	453_H	0.675	1.00
215_V	218_L	0.674	1.00
104_V	107_H	0.674	1.00
283_L	290_I	0.674	1.00
470_M	474_G	0.673	1.00
131_T	135_K	0.670	1.00
275_D	278_E	0.667	1.00
452_A	456_I	0.665	1.00
146_R	149_K	0.665	1.00
67_W	70_E	0.664	0.99
140_I	147_Y	0.662	0.99
355_R	362_L	0.661	0.99
424_K	428_E	0.659	0.99
117_S	121_K	0.657	0.99
204_N	208_L	0.657	0.99
359_I	366_V	0.656	0.99
73_E	78_H	0.655	0.99
459_T	463_L	0.653	0.99
382_E	385_A	0.642	0.99
133_E	137_R	0.640	0.99
303_A	308_L	0.640	0.99
493_E	496_E	0.637	0.99
413_L	416_R	0.636	0.99
481_E	484_V	0.635	0.99
120_E	124_R	0.634	0.99
129_L	132_S	0.634	0.99
361_K	365_S	0.633	0.99
321_L	324_E	0.631	0.99
502_E	506_Q	0.631	0.99
412_E	419_L	0.630	0.99
111_L	118_S	0.629	0.99
338_S	341_L	0.628	0.99
342_T	349_Q	0.628	0.99
152_K	156_A	0.628	0.99
166_D	169_E	0.624	0.99
391_I	398_H	0.624	0.99
167_S	170_K	0.623	0.99
305_Q	309_S	0.623	0.99
220_A	224_Q	0.623	0.99
465_E	469_N	0.621	0.99
471_E	475_A	0.618	0.99
168_L	172_L	0.618	0.99
451_N	454_H	0.618	0.99
356_L	360_G	0.616	0.99
101_A	104_V	0.615	0.99
61_E	64_F	0.614	0.99
512_R	515_N	0.613	0.99
406_Q	410_K	0.608	0.99
308_L	311_M	0.607	0.99
206_E	210_S	0.606	0.99
383_E	386_S	0.605	0.99
356_L	363_L	0.604	0.99
203_R	206_E	0.602	0.99
296_Q	300_E	0.602	0.99
95_K	98_F	0.602	0.99
395_K	398_H	0.602	0.99
366_V	369_K	0.601	0.99
333_E	336_K	0.601	0.99
319_D	322_K	0.600	0.99
447_E	450_E	0.597	0.99
131_T	134_E	0.596	0.99
349_Q	362_L	0.595	0.99
297_L	301_V	0.593	0.99
252_L	256_L	0.592	0.99
345_E	348_K	0.591	0.99
288_E	291_Q	0.589	0.99
166_D	170_K	0.587	0.99
102_N	106_V	0.584	0.99
301_V	304_G	0.583	0.99
440_G	443_S	0.583	0.99
136_S	139_E	0.582	0.99
240_M	243_K	0.580	0.99
78_H	82_V	0.578	0.99
62_E	65_E	0.575	0.99
477_L	484_V	0.574	0.99
154_L	157_Y	0.574	0.99
233_L	236_G	0.573	0.99
111_L	126_I	0.570	0.98
226_V	230_I	0.570	0.98
157_Y	162_G	0.567	0.98
254_K	257_E	0.566	0.98
110_D	113_T	0.566	0.98
426_I	430_A	0.566	0.98
415_A	425_T	0.564	0.98
391_I	405_L	0.564	0.98
246_K	249_H	0.563	0.98
307_V	310_K	0.563	0.98
98_F	102_N	0.562	0.98
290_I	304_G	0.562	0.98
461_N	465_E	0.562	0.98
319_D	323_E	0.561	0.98
282_I	286_I	0.560	0.98
229_Q	236_G	0.559	0.98
397_E	402_R	0.557	0.98
189_G	193_T	0.553	0.98
294_Y	298_E	0.552	0.98
375_V	379_L	0.551	0.98
259_L	263_L	0.551	0.98
461_N	464_N	0.551	0.98
78_H	81_K	0.551	0.98
108_I	111_L	0.549	0.98
460_V	464_N	0.547	0.98
390_Q	394_V	0.547	0.98
255_E	259_L	0.545	0.98
417_E	420_S	0.545	0.98
442_P	449_L	0.544	0.98
309_S	312_P	0.542	0.98
165_Y	169_E	0.540	0.98
183_E	186_T	0.538	0.98
424_K	427_S	0.537	0.98
214_D	217_K	0.536	0.98
256_L	260_S	0.534	0.98
330_A	333_E	0.533	0.98
397_E	401_Y	0.533	0.98
144_R	147_Y	0.532	0.98
134_E	138_E	0.531	0.98
53_H	56_M	0.531	0.98
452_A	459_T	0.529	0.98
394_V	398_H	0.528	0.97
217_K	220_A	0.526	0.97
85_L	93_A	0.525	0.97
97_R	102_N	0.524	0.97
89_A	93_A	0.524	0.97
452_A	455_H	0.524	0.97
101_A	105_L	0.523	0.97
362_L	370_L	0.522	0.97
378_S	382_E	0.521	0.97
337_E	340_R	0.520	0.97
122_I	133_E	0.517	0.97
162_G	165_Y	0.517	0.97
225_T	228_G	0.515	0.97
100_K	103_Q	0.515	0.97
409_R	412_E	0.515	0.97
277_D	280_S	0.514	0.97
352_F	359_I	0.513	0.97
414_Q	417_E	0.512	0.97
168_L	175_I	0.512	0.97
468_L	472_E	0.512	0.97
211_Y	215_V	0.511	0.97
178_G	182_F	0.510	0.97
112_L	122_I	0.510	0.97
105_L	112_L	0.510	0.97
107_H	110_D	0.510	0.97
164_L	169_E	0.509	0.97
63_F	67_W	0.509	0.97
360_G	363_L	0.507	0.97
476_H	480_A	0.507	0.97
487_A	491_S	0.506	0.97
259_L	266_A	0.500	0.97
480_A	483_I	0.500	0.97
84_E	88_D	0.500	0.97

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4uxvA	1	0.927	100	0.367	Contact Map
1i84S	2	0.2544	99.6	0.654	Contact Map
1c1gA	2	0.5053	99.2	0.72	Contact Map
4uy3A	1	0.3452	99.1	0.738	Contact Map
3r6nA	1	0.7135	97.9	0.818	Contact Map
1hciA	2	0.7473	97.8	0.821	Contact Map
2dfsA	2	0.3132	97.5	0.831	Contact Map
1u4qA	1	0.5	97.4	0.834	Contact Map
3kbtA	1	0.4164	97	0.845	Contact Map
3edvA	2	0.532	96.8	0.85	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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