YTCB - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YTCB - Uncharacterized UDP-glucose epimerase YtcB

UniProt:	O34886	Sequences: MKILVTGAAGFIGSHLCEELLKDKKHNVIGIDDFIGPTPFSLKLKNLKNLLPEKRFTFIKENLLTADLASLLEGVDVIFHLAAIPGVRSSWGNHFHPYAAHNIQALQRLLEACREHSIQTFVFASTSSVYGEKQGKVSENTSLSPLSPYGVTKLTGEKLCHVYKQSFGIPIVILRFFTVYGPRQRPDMAFHRLIKQHLQQKPLTIFGDGQQSRDFTYISDCVKGITAVLGKPHLIGETVNIGGAERASVLKVVSLIEDISGRKATLHFSDKIAGEPSNTWADISKAKQLLHYDPATSLKDGLTNEIAYLSSLYQGE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	316 (286)
Sequences:	60188 (41727)
Seq/√Len:	2467.4

ECOLI - GALE RMLB1 RMLB2 GM4D YBJS HLDD FCL YFCH RMLD YEEZ QOR2 ARNA YBJT YRAR
BACSU - YTCB GALE RMLB YFNG YFHF SPSK YTBQ YWNB YESF YHFK YHEG EPSC
HALSA - Q9HSV1 Q9HSU9 Q9HRD1 Q9HSE7 Q9HML4 Q9HS50 Q9HSQ3 Q9HPF1 Q9HNV3 Q9HR86
SULSO - Q97VN5 Q7LXE8 Q7LXG5 Q980W1 Q97XJ9 Q97XG1 Q97UM3 Q7LX44 Q7LXE6 Q97XF9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
8_A	30_G	3.436	1.00
224_G	241_I	2.884	1.00
19_E	223_K	2.776	1.00
237_E	285_K	2.773	1.00
255_L	299_K	2.708	1.00
69_A	115_E	2.692	1.00
297_S	300_D	2.659	1.00
258_D	299_K	2.472	1.00
77_V	229_L	2.403	1.00
100_A	104_Q	2.399	1.00
6_T	80_H	2.308	1.00
284_S	288_Q	2.281	1.00
31_I	61_E	2.266	1.00
120_T	170_P	2.254	1.00
287_K	293_D	2.252	1.00
80_H	123_F	2.235	1.00
124_A	225_I	2.232	1.00
180_Y	301_G	2.211	1.00
5_V	17_C	2.204	1.00
79_F	229_L	2.107	1.00
223_K	295_A	2.053	1.00
4_L	75_V	2.042	1.00
19_E	226_T	2.006	1.00
29_I	57_T	1.894	1.00
250_L	254_S	1.893	1.00
223_K	227_A	1.887	1.00
24_K	230_G	1.887	1.00
29_I	75_V	1.836	1.00
259_I	303_T	1.826	1.00
219_S	304_N	1.814	1.00
176_F	225_I	1.800	1.00
248_S	251_K	1.776	1.00
93_N	97_P	1.764	1.00
27_N	57_T	1.748	1.00
255_L	258_D	1.743	1.00
19_E	24_K	1.736	1.00
16_L	79_F	1.731	1.00
160_C	171_I	1.731	1.00
16_L	222_V	1.730	1.00
138_S	141_T	1.727	1.00
64_L	100_A	1.726	1.00
174_L	228_V	1.673	1.00
125_S	129_V	1.660	1.00
217_Y	304_N	1.639	1.00
244_A	287_K	1.635	1.00
130_Y	240_N	1.631	1.00
34_F	58_F	1.630	1.00
29_I	59_I	1.612	1.00
80_H	106_L	1.604	1.00
66_A	111_E	1.601	1.00
251_K	254_S	1.601	1.00
12_I	179_V	1.598	1.00
16_L	81_L	1.564	1.00
286_A	290_L	1.563	1.00
107_Q	111_E	1.558	1.00
139_E	285_K	1.555	1.00
69_A	112_A	1.551	1.00
195_K	199_Q	1.546	1.00
174_L	225_I	1.526	1.00
107_Q	159_L	1.524	1.00
255_L	259_I	1.518	1.00
303_T	307_A	1.517	1.00
76_D	119_Q	1.510	1.00
79_F	225_I	1.485	1.00
78_I	113_C	1.479	1.00
149_Y	153_K	1.472	1.00
19_E	22_K	1.472	1.00
202_P	267_H	1.454	1.00
104_Q	107_Q	1.449	1.00
217_Y	301_G	1.444	1.00
99_A	155_T	1.442	1.00
283_I	287_K	1.437	1.00
102_N	152_T	1.434	1.00
19_E	222_V	1.433	1.00
109_L	121_F	1.427	1.00
96_H	100_A	1.406	1.00
218_I	222_V	1.403	1.00
81_L	124_A	1.394	1.00
176_F	221_C	1.375	1.00
177_F	281_A	1.368	1.00
26_H	230_G	1.367	1.00
226_T	230_G	1.365	1.00
17_C	30_G	1.364	1.00
120_T	172_V	1.358	1.00
18_E	183_R	1.356	1.00
66_A	108_R	1.355	1.00
69_A	116_H	1.330	1.00
300_D	303_T	1.325	1.00
154_L	158_K	1.322	1.00
143_L	154_L	1.319	1.00
124_A	176_F	1.305	1.00
227_A	231_K	1.301	1.00
216_T	221_C	1.301	1.00
138_S	282_D	1.301	1.00
9_A	32_D	1.296	1.00
196_Q	201_K	1.293	1.00
72_L	78_I	1.286	1.00
106_L	156_G	1.285	1.00
250_L	268_F	1.283	1.00
114_R	167_F	1.280	1.00
111_E	114_R	1.275	1.00
110_L	163_Y	1.275	1.00
214_D	244_A	1.274	1.00
158_K	161_H	1.269	1.00
300_D	304_N	1.259	1.00
3_I	26_H	1.250	1.00
283_I	294_P	1.244	1.00
20_L	226_T	1.217	1.00
111_E	115_E	1.216	1.00
175_R	238_T	1.209	1.00
8_A	17_C	1.208	1.00
63_L	105_A	1.200	1.00
21_L	56_F	1.172	1.00
161_H	238_T	1.169	1.00
113_C	121_F	1.169	1.00
223_K	292_Y	1.150	1.00
123_F	156_G	1.150	1.00
157_E	175_R	1.145	1.00
212_S	246_R	1.128	1.00
29_I	73_E	1.126	1.00
175_R	240_N	1.124	1.00
11_F	181_G	1.124	1.00
224_G	286_A	1.119	1.00
24_K	226_T	1.111	1.00
63_L	82_A	1.110	1.00
161_H	173_I	1.110	1.00
113_C	118_I	1.106	1.00
81_L	225_I	1.105	1.00
217_Y	220_D	1.097	1.00
123_F	160_C	1.092	1.00
18_E	22_K	1.088	1.00
151_V	155_T	1.084	1.00
140_N	285_K	1.084	1.00
204_T	267_H	1.081	1.00
180_Y	217_Y	1.078	1.00
66_A	69_A	1.076	1.00
247_A	298_L	1.072	1.00
220_D	243_G	1.071	1.00
14_S	183_R	1.062	1.00
31_I	68_L	1.052	1.00
30_G	56_F	1.049	1.00
112_A	116_H	1.049	1.00
15_H	219_S	1.049	1.00
72_L	75_V	1.046	1.00
110_L	121_F	1.044	1.00
257_E	263_K	1.036	1.00
4_L	31_I	1.034	1.00
210_Q	250_L	1.034	1.00
19_E	219_S	1.032	1.00
6_T	82_A	1.025	1.00
101_H	105_A	1.022	1.00
122_V	174_L	1.022	1.00
57_T	73_E	1.019	1.00
269_S	272_I	1.019	1.00
110_L	159_L	1.003	1.00
125_S	157_E	0.993	1.00
159_L	162_V	0.989	1.00
299_K	303_T	0.987	1.00
11_F	218_I	0.985	1.00
21_L	55_R	0.982	1.00
164_K	171_I	0.981	1.00
227_A	290_L	0.981	1.00
26_H	76_D	0.978	1.00
3_I	20_L	0.977	1.00
29_I	74_G	0.974	1.00
239_V	285_K	0.972	1.00
137_V	141_T	0.970	1.00
161_H	171_I	0.967	1.00
123_F	173_I	0.966	1.00
135_G	138_S	0.965	1.00
259_I	306_I	0.963	1.00
179_V	221_C	0.961	1.00
114_R	169_I	0.959	1.00
246_R	278_N	0.952	1.00
59_I	71_L	0.951	1.00
16_L	20_L	0.949	1.00
254_S	257_E	0.944	1.00
259_I	302_L	0.942	1.00
67_D	70_S	0.941	1.00
84_I	101_H	0.941	1.00
3_I	77_V	0.933	1.00
224_G	292_Y	0.933	1.00
121_F	160_C	0.927	1.00
179_V	216_T	0.925	1.00
170_P	235_I	0.921	1.00
110_L	160_C	0.920	1.00
108_R	111_E	0.918	1.00
162_V	166_S	0.912	1.00
242_G	281_A	0.912	1.00
260_S	306_I	0.906	1.00
68_L	112_A	0.906	1.00
98_Y	152_T	0.903	1.00
161_H	165_Q	0.900	1.00
241_I	286_A	0.896	1.00
228_V	290_L	0.895	1.00
104_Q	108_R	0.895	1.00
174_L	241_I	0.894	1.00
189_A	193_L	0.890	1.00
202_P	265_T	0.890	1.00
21_L	28_V	0.889	1.00
72_L	116_H	0.888	1.00
15_H	218_I	0.886	1.00
33_D	62_N	0.886	1.00
228_V	286_A	0.885	1.00
285_K	288_Q	0.884	1.00
172_V	228_V	0.880	1.00
145_P	150_G	0.879	1.00
31_I	71_L	0.875	1.00
212_S	248_S	0.874	1.00
270_D	273_A	0.874	1.00
173_I	238_T	0.871	1.00
72_L	112_A	0.864	1.00
195_K	198_L	0.861	1.00
17_C	28_V	0.856	1.00
246_R	280_W	0.855	1.00
234_L	237_E	0.851	1.00
99_A	103_I	0.845	1.00
247_A	251_K	0.842	1.00
247_A	252_V	0.838	1.00
242_G	283_I	0.834	1.00
210_Q	248_S	0.833	1.00
127_S	177_F	0.832	1.00
35_I	60_K	0.830	1.00
25_K	28_V	0.830	1.00
304_N	307_A	0.827	1.00
66_A	115_E	0.822	1.00
15_H	19_E	0.818	1.00
105_A	108_R	0.818	1.00
188_M	191_H	0.817	1.00
135_G	141_T	0.815	1.00
129_V	157_E	0.814	1.00
72_L	113_C	0.813	1.00
177_F	242_G	0.812	1.00
6_T	109_L	0.810	1.00
192_R	196_Q	0.808	1.00
4_L	61_E	0.807	1.00
99_A	152_T	0.807	1.00
227_A	291_H	0.805	1.00
257_E	262_R	0.804	1.00
15_H	18_E	0.800	1.00
12_I	221_C	0.793	1.00
89_S	93_N	0.793	1.00
3_I	79_F	0.792	1.00
244_A	283_I	0.790	1.00
15_H	222_V	0.789	1.00
64_L	101_H	0.787	1.00
259_I	299_K	0.786	1.00
62_N	65_T	0.782	1.00
34_F	60_K	0.774	1.00
209_G	250_L	0.773	1.00
254_S	258_D	0.771	1.00
257_E	264_A	0.770	1.00
112_A	115_E	0.770	1.00
99_A	104_Q	0.769	1.00
91_W	148_P	0.765	1.00
155_T	158_K	0.765	1.00
84_I	102_N	0.765	1.00
139_E	286_A	0.763	1.00
119_Q	170_P	0.759	1.00
108_R	112_A	0.757	1.00
245_E	297_S	0.754	1.00
16_L	225_I	0.752	1.00
163_Y	167_F	0.750	1.00
32_D	58_F	0.750	1.00
212_S	278_N	0.749	1.00
3_I	229_L	0.748	1.00
227_A	230_G	0.747	1.00
103_I	155_T	0.747	1.00
114_R	168_G	0.739	1.00
192_R	195_K	0.739	1.00
4_L	78_I	0.737	1.00
106_L	110_L	0.732	1.00
78_I	109_L	0.726	1.00
156_G	160_C	0.723	1.00
227_A	292_Y	0.720	1.00
284_S	287_K	0.718	1.00
68_L	108_R	0.716	1.00
139_E	240_N	0.715	1.00
223_K	226_T	0.715	1.00
231_K	234_L	0.713	1.00
20_L	229_L	0.712	1.00
111_E	163_Y	0.711	1.00
78_I	121_F	0.701	1.00
182_P	304_N	0.699	1.00
133_K	137_V	0.696	1.00
106_L	160_C	0.695	1.00
182_P	217_Y	0.694	1.00
77_V	120_T	0.694	1.00
252_V	298_L	0.694	1.00
197_H	257_E	0.693	1.00
80_H	109_L	0.690	1.00
71_L	75_V	0.690	1.00
97_P	100_A	0.686	1.00
214_D	243_G	0.684	1.00
84_I	98_Y	0.666	1.00
83_A	102_N	0.665	1.00
65_T	68_L	0.662	1.00
255_L	298_L	0.661	1.00
102_N	149_Y	0.659	1.00
52_P	56_F	0.656	1.00
245_E	299_K	0.656	1.00
193_L	196_Q	0.656	1.00
220_D	295_A	0.655	1.00
126_T	129_V	0.654	1.00
84_I	97_P	0.654	1.00
53_E	56_F	0.654	1.00
97_P	101_H	0.652	1.00
158_K	162_V	0.649	1.00
14_S	18_E	0.649	1.00
251_K	255_L	0.649	1.00
222_V	226_T	0.646	1.00
194_I	256_I	0.642	1.00
145_P	154_L	0.640	1.00
29_I	71_L	0.636	1.00
147_S	150_G	0.636	1.00
99_A	151_V	0.636	1.00
128_S	150_G	0.635	1.00
59_I	73_E	0.634	1.00
239_V	286_A	0.632	1.00
129_V	143_L	0.632	1.00
114_R	163_Y	0.631	1.00
27_N	55_R	0.631	1.00
178_T	213_R	0.629	1.00
155_T	159_L	0.629	1.00
127_S	281_A	0.627	1.00
134_Q	141_T	0.627	1.00
151_V	158_K	0.627	1.00
287_K	294_P	0.625	1.00
126_T	153_K	0.625	1.00
160_C	173_I	0.624	1.00
194_I	198_L	0.624	1.00
211_Q	249_V	0.624	1.00
266_L	269_S	0.622	1.00
180_Y	243_G	0.621	1.00
174_L	224_G	0.618	1.00
106_L	123_F	0.614	1.00
120_T	232_P	0.611	1.00
214_D	246_R	0.610	1.00
221_C	241_I	0.605	1.00
152_T	156_G	0.603	1.00
70_S	73_E	0.603	1.00
77_V	122_V	0.603	1.00
171_I	236_G	0.602	1.00
26_H	77_V	0.600	1.00
151_V	162_V	0.600	1.00
136_K	282_D	0.600	1.00
259_I	307_A	0.599	1.00
77_V	119_Q	0.599	1.00
9_A	34_F	0.597	1.00
194_I	306_I	0.596	1.00
255_L	302_L	0.596	1.00
122_V	229_L	0.595	1.00
124_A	174_L	0.593	1.00
220_D	223_K	0.591	1.00
235_I	239_V	0.591	1.00
93_N	96_H	0.590	1.00
276_P	279_T	0.586	1.00
182_P	185_R	0.585	1.00
122_V	228_V	0.585	1.00
253_V	257_E	0.581	1.00
193_L	197_H	0.580	1.00
9_A	33_D	0.576	1.00
81_L	176_F	0.574	1.00
5_V	20_L	0.572	1.00
4_L	72_L	0.570	1.00
4_L	71_L	0.570	1.00
20_L	79_F	0.570	1.00
267_H	270_D	0.568	1.00
269_S	273_A	0.567	1.00
295_A	300_D	0.566	1.00
149_Y	152_T	0.565	1.00
226_T	229_L	0.563	1.00
232_P	235_I	0.558	1.00
79_F	226_T	0.554	1.00
197_H	256_I	0.554	1.00
5_V	30_G	0.554	1.00
200_Q	203_L	0.553	1.00
148_P	151_V	0.553	1.00
159_L	163_Y	0.552	1.00
32_D	36_G	0.550	1.00
184_Q	187_D	0.550	1.00
80_H	121_F	0.549	1.00
200_Q	262_R	0.547	1.00
205_I	268_F	0.547	1.00
176_F	179_V	0.546	1.00
257_E	260_S	0.545	1.00
110_L	114_R	0.545	1.00
212_S	280_W	0.545	1.00
25_K	55_R	0.543	1.00
197_H	203_L	0.542	1.00
148_P	152_T	0.542	1.00
143_L	158_K	0.538	1.00
61_E	71_L	0.538	1.00
182_P	219_S	0.538	1.00
15_H	183_R	0.532	1.00
301_G	304_N	0.532	1.00
78_I	118_I	0.531	1.00
177_F	214_D	0.530	1.00
136_K	280_W	0.529	1.00
172_V	237_E	0.527	1.00
204_T	269_S	0.526	1.00
256_I	306_I	0.526	1.00
113_C	116_H	0.524	1.00
184_Q	188_M	0.523	1.00
18_E	219_S	0.523	1.00
263_K	266_L	0.522	1.00
178_T	215_F	0.522	1.00
26_H	226_T	0.521	1.00
153_K	156_G	0.520	1.00
213_R	249_V	0.519	1.00
16_L	226_T	0.518	1.00
131_G	144_S	0.517	1.00
256_I	302_L	0.516	1.00
181_G	218_I	0.516	1.00
247_A	255_L	0.515	1.00
11_F	15_H	0.514	1.00
31_I	59_I	0.513	1.00
143_L	238_T	0.511	1.00
217_Y	305_E	0.510	1.00
68_L	72_L	0.510	1.00
196_Q	204_T	0.510	1.00
7_G	10_G	0.507	1.00
85_P	188_M	0.505	1.00
17_C	21_L	0.504	1.00
283_I	292_Y	0.504	1.00
196_Q	200_Q	0.503	1.00
231_K	239_V	0.502	1.00
138_S	284_S	0.501	1.00
208_D	277_S	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1sb8A	2	0.9715	100	0.155	Contact Map
3rufA	2	0.9747	100	0.161	Contact Map
1orrA	3	0.9684	100	0.174	Contact Map
2q1sA	2	0.9335	100	0.177	Contact Map
3m2pA	2	0.9241	100	0.178	Contact Map
1rkxA	3	0.962	100	0.178	Contact Map
2hunA	2	0.9778	100	0.179	Contact Map
1rpnA	4	0.9747	100	0.181	Contact Map
1oc2A	2	0.9778	100	0.182	Contact Map
4wkgA	5	0.9652	100	0.183	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.009 seconds.