GREMLIN Database
YTKC - Uncharacterized protein YtkC
UniProt: O34883 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 134 (124)
Sequences: 696 (555)
Seq/√Len: 49.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
36_M69_L6.1051.00
46_K110_S3.7271.00
26_Q89_R3.3651.00
50_I110_S2.7851.00
58_V99_Y2.6391.00
75_C92_A2.4231.00
34_S77_F2.2601.00
43_T103_Q2.1741.00
38_I70_A2.1381.00
109_S126_L2.1321.00
55_F103_Q2.1241.00
101_S123_L2.0221.00
49_I60_A1.9981.00
109_S115_V1.9971.00
35_L97_I1.9230.99
39_E103_Q1.9080.99
39_E43_T1.8900.99
117_Q121_D1.8840.99
121_D128_N1.8410.99
68_T96_Y1.8240.99
62_L99_Y1.6550.98
61_R103_Q1.6190.98
43_T55_F1.6030.98
44_T102_V1.5430.97
67_V108_A1.4750.96
101_S125_T1.4270.95
7_I11_L1.4010.95
65_K100_E1.4000.95
39_E61_R1.3980.95
39_E55_F1.3790.94
104_I111_L1.3460.94
32_L72_I1.3340.93
39_E106_V1.3320.93
43_T61_R1.3240.93
14_S128_N1.3220.93
49_I112_G1.3040.93
13_V16_S1.3020.93
103_Q106_V1.2820.92
108_A113_I1.2600.91
31_I77_F1.2550.91
21_F73_S1.2520.91
58_V62_L1.2450.91
47_E51_H1.2440.91
8_F12_A1.2330.90
62_L73_S1.2250.90
13_V20_F1.2030.89
7_I10_F1.2000.89
12_A19_G1.1980.89
55_F61_R1.1930.89
53_L102_V1.1740.88
28_S93_I1.1730.88
49_I111_L1.1720.88
109_S123_L1.1470.87
48_T122_L1.1300.86
66_L73_S1.1160.85
87_S127_K1.1140.85
31_I97_I1.1140.85
46_K50_I1.1100.85
72_I93_I1.1070.85
95_F114_P1.1060.85
55_F106_V1.0770.83
43_T106_V1.0670.82
105_V123_L1.0550.82
38_I104_I1.0280.80
66_L71_L1.0100.79
33_L70_A0.9920.78
81_L97_I0.9760.76
42_S107_T0.9440.74
41_I45_L0.9200.72
115_V120_V0.9120.71
40_F60_A0.9010.70
40_F46_K0.8920.70
117_Q120_V0.8650.67
35_L78_F0.8610.67
14_S21_F0.8600.67
120_V124_E0.8590.67
22_F26_Q0.8560.67
45_L63_V0.8450.66
40_F99_Y0.8240.64
16_S19_G0.8220.63
30_L34_S0.7940.61
67_V127_K0.7850.60
54_S124_E0.7830.60
29_F33_L0.7770.59
31_I35_L0.7670.58
61_R106_V0.7660.58
67_V111_L0.7610.57
105_V119_L0.7570.57
64_K74_V0.7520.56
59_F68_T0.7510.56
18_A22_F0.7470.56
98_L101_S0.7450.56
37_A41_I0.7370.55
27_Y70_A0.7360.55
31_I81_L0.7290.54
11_L128_N0.7280.54
56_K124_E0.7280.54
40_F58_V0.7270.54
47_E106_V0.7240.54
76_H93_I0.7190.53
91_L94_M0.7190.53
59_F64_K0.7130.53
10_F13_V0.7070.52
12_A94_M0.7070.52
71_L96_Y0.7070.52
19_G94_M0.7050.52
105_V115_V0.7050.52
49_I63_V0.7040.52
36_M56_K0.6930.50
10_F20_F0.6920.50
76_H80_Q0.6890.50
108_A115_V0.6870.50
13_V29_F0.6810.49
64_K67_V0.6780.49
25_F29_F0.6780.49
7_I83_N0.6760.49
71_L92_A0.6750.49
47_E61_R0.6740.49
97_I101_S0.6680.48
9_S14_S0.6650.48
32_L102_V0.6650.48
114_P120_V0.6640.48
49_I114_P0.6570.47
17_A20_F0.6500.46
8_F62_L0.6500.46
20_F30_L0.6500.46
60_A64_K0.6420.45
40_F57_K0.6420.45
44_T75_C0.6400.45
54_S60_A0.6370.45
51_H76_H0.6340.44
9_S13_V0.6320.44
53_L58_V0.6290.44
22_F89_R0.6240.43
19_G22_F0.6230.43
39_E107_T0.6170.43
35_L74_V0.6140.42
47_E99_Y0.6090.42
9_S12_A0.6080.42
37_A69_L0.6030.41
7_I14_S0.6010.41
40_F44_T0.6000.41
35_L101_S0.5990.41
7_I67_V0.5980.41
51_H125_T0.5980.41
94_M98_L0.5960.41
42_S57_K0.5830.39
22_F29_F0.5830.39
62_L66_L0.5820.39
64_K68_T0.5760.39
64_K96_Y0.5750.39
75_C85_Q0.5710.38
48_T53_L0.5710.38
78_F101_S0.5700.38
44_T48_T0.5690.38
40_F89_R0.5690.38
76_H115_V0.5640.38
103_Q107_T0.5610.37
15_V19_G0.5600.37
26_Q125_T0.5540.37
74_V101_S0.5540.37
28_S94_M0.5520.36
24_G89_R0.5510.36
20_F95_F0.5500.36
44_T51_H0.5450.36
35_L113_I0.5450.36
46_K63_V0.5430.36
61_R107_T0.5410.35
118_M130_F0.5400.35
57_K124_E0.5360.35
81_L113_I0.5340.35
20_F51_H0.5320.35
26_Q76_H0.5310.34
59_F96_Y0.5310.34
66_L78_F0.5300.34
8_F16_S0.5260.34
10_F38_I0.5220.34
65_K79_D0.5190.33
117_Q128_N0.5190.33
28_S81_L0.5180.33
56_K60_A0.5150.33
39_E47_E0.5100.33
48_T51_H0.5040.32
67_V97_I0.5040.32
29_F121_D0.5020.32
21_F27_Y0.5000.32
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4dveA 3 0.4776 6.8 0.946 Contact Map
2ay0A 2 0.209 4.9 0.95 Contact Map
4me7E 2 0.209 4.5 0.951 Contact Map
1t6sA 4 0.4104 4.4 0.951 Contact Map
2izxA 2 0.1642 4.2 0.951 Contact Map
2m8eA 1 0.4179 3.9 0.952 Contact Map
3hrsA 2 0.3731 3.7 0.952 Contact Map
2k5jA 2 0.2463 3.5 0.953 Contact Map
1kvdA 1 0.4254 3.3 0.954 Contact Map
3d5pA 2 0.3731 3.2 0.954 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.006 seconds.