GREMLIN Database
YLQH - Uncharacterized protein YlqH
UniProt: O34867 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 93 (84)
Sequences: 2682 (1822)
Seq/√Len: 198.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
36_N39_K3.7761.00
40_E43_K3.2471.00
16_D19_K3.0141.00
20_D24_R2.4301.00
21_K66_Q2.2091.00
40_E44_A2.0871.00
54_L78_I2.0821.00
35_D38_I1.8111.00
11_V25_V1.7741.00
80_S83_Y1.7641.00
9_K30_K1.7281.00
38_I42_K1.7271.00
10_A35_D1.7221.00
32_H35_D1.6451.00
14_H26_I1.5851.00
24_R66_Q1.5391.00
9_K56_E1.5141.00
9_K55_V1.4971.00
39_K43_K1.4431.00
79_F82_I1.3941.00
76_A80_S1.3711.00
49_Q81_F1.3201.00
36_N40_E1.3131.00
25_V61_L1.2691.00
11_V28_T1.2261.00
25_V58_M1.2141.00
69_E72_Y1.2021.00
39_K42_K1.2001.00
31_G35_D1.1831.00
17_E87_E1.1771.00
71_L79_F1.1731.00
38_I55_V1.1571.00
57_L71_L1.1491.00
81_F85_L1.1471.00
73_E77_E1.1351.00
22_A72_Y1.1331.00
76_A79_F1.1071.00
20_D66_Q1.1041.00
14_H24_R1.1031.00
9_K31_G1.0831.00
10_A38_I1.0811.00
12_A27_A1.0551.00
22_A66_Q1.0451.00
11_V58_M1.0441.00
11_V59_R1.0311.00
60_H70_A1.0281.00
35_D48_I1.0071.00
56_E59_R0.9941.00
9_K52_R0.9871.00
5_T56_E0.9811.00
35_D39_K0.9540.99
82_I85_L0.9510.99
6_P56_E0.9460.99
5_T8_R0.9210.99
21_K24_R0.9170.99
7_I30_K0.8870.99
32_H36_N0.8850.99
75_V79_F0.8830.99
15_Y68_P0.8570.99
28_T62_T0.8490.99
28_T64_D0.8490.99
68_P71_L0.8410.98
77_E81_F0.8350.98
8_R56_E0.8310.98
67_I75_V0.8230.98
13_L79_F0.8130.98
14_H20_D0.7970.98
49_Q78_I0.7950.98
48_I52_R0.7950.98
53_T57_L0.7890.98
84_K88_S0.7730.97
51_D77_E0.7570.97
64_D80_S0.7570.97
78_I82_I0.7540.97
42_K48_I0.7540.97
57_L60_H0.7510.97
14_H19_K0.7450.97
71_L80_S0.7390.97
54_L75_V0.7260.96
32_H39_K0.7130.96
8_R35_D0.7110.96
17_E20_D0.7040.96
61_L65_D0.6940.95
15_Y77_E0.6850.95
8_R31_G0.6770.94
8_R38_I0.6760.94
84_K87_E0.6730.94
38_I50_E0.6610.94
7_I56_E0.6540.93
79_F83_Y0.6500.93
42_K50_E0.6390.93
74_T78_I0.6340.92
17_E83_Y0.6290.92
51_D81_F0.6280.92
33_V36_N0.6270.92
71_L78_I0.6270.92
28_T61_L0.6240.92
25_V28_T0.6210.92
18_Q45_G0.6200.91
35_D42_K0.6170.91
30_K35_D0.6030.90
58_M61_L0.6010.90
76_A81_F0.5940.90
12_A26_I0.5920.89
51_D70_A0.5850.89
50_E54_L0.5840.89
53_T86_D0.5810.89
68_P78_I0.5650.87
26_I46_V0.5630.87
54_L71_L0.5500.86
57_L74_T0.5460.85
25_V72_Y0.5440.85
38_I72_Y0.5400.85
36_N67_I0.5400.85
73_E86_D0.5370.84
25_V71_L0.5350.84
80_S84_K0.5350.84
26_I63_V0.5300.84
17_E60_H0.5270.83
15_Y38_I0.5250.83
26_I37_I0.5210.83
58_M75_V0.5170.82
62_T65_D0.5160.82
49_Q77_E0.5140.82
31_G54_L0.5100.81
37_I74_T0.5000.80
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2jljA 2 0.914 100 0.157 Contact Map
3bzsA 1 0.8925 100 0.164 Contact Map
3t7yA 2 0.9032 100 0.178 Contact Map
3b0zB 1 0.8925 100 0.18 Contact Map
3c01E 2 0.9355 100 0.184 Contact Map
3bzyB 3 0.8817 100 0.185 Contact Map
3b1sB 1 0.9032 100 0.186 Contact Map
2vt1B 1 0.8602 100 0.186 Contact Map
2jliA 1 0.8602 100 0.197 Contact Map
3zeyG 1 0.9677 69.6 0.887 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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