YOAC - BACSU - GREMLIN Contacts

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YOAC - Putative sugar kinase YoaC

UniProt:	O34861	Sequences: MKKQKGYLVFDIGTGNARVAVVSVTGSVLTVEREDIEYSTETLYPDSRYFSPQVLWKQVMNLAKRALSRSCDIDIIGLTSTSQRQGIVLIDQNGNPFLGLPNIDNRGREWEAGIPDWEEIYSSTGRLPTALFSALKLYGLKQRQPSLWEKTASFTSISDWVTYQLSGILTYEPSQATETLLFDVKQNTWSEEMCDIFGFSPSILPPLVRAGTAIGTIANEYASELGLSINAKVIAGGGDTQLAVKSTGAGLEDIVIVSGTTTPITKITEDHGDTKHKAWLNCHTDQGHWLVETNPGITGLNYQKLKQIFYPNETYEVMEEEISALAKEDHACVAALGSYLSAEKNALTRGGFLFDAPLSAHLKRAHFVRAALEEIAFSIKWNFDILTEVTPFERDYVWVCGGGFQSKALTQYIADLLQKKVYVQEGYHQASVVGAAVICNETFQLTEEMSANVRVIEPKDCQIELALYEEWKQTQRFFSGSESKVLI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	487 (462)
Sequences:	12519 (8549)
Seq/√Len:	397.7

ECOLI - LSRK ARAB LYXK GLPK XYLB RHAB FUCK YGCE
BACSU - YOAC GNTK XYLB ARAB GLPK RHAB
HALSA - GLPK
SULSO - GLPK1 GLPK2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
110_W	142_Q	3.812	1.00
191_E	201_P	3.758	1.00
23_S	27_S	3.468	1.00
19_V	62_L	3.383	1.00
113_G	142_Q	3.343	1.00
380_K	384_D	2.948	1.00
183_D	186_Q	2.824	1.00
411_Q	415_D	2.791	1.00
387_T	419_K	2.774	1.00
123_S	190_S	2.772	1.00
97_F	147_L	2.736	1.00
325_L	366_H	2.702	1.00
34_E	61_N	2.699	1.00
352_F	367_F	2.687	1.00
182_F	207_L	2.682	1.00
168_I	206_P	2.641	1.00
41_E	99_G	2.619	1.00
396_Y	422_Y	2.603	1.00
32_E	65_R	2.577	1.00
209_R	212_T	2.567	1.00
34_E	65_R	2.517	1.00
98_L	144_Q	2.505	1.00
92_Q	152_A	2.489	1.00
448_E	451_A	2.477	1.00
56_W	164_Q	2.454	1.00
462_Q	465_L	2.439	1.00
53_Q	164_Q	2.437	1.00
91_D	150_K	2.409	1.00
21_V	66_A	2.371	1.00
447_E	451_A	2.335	1.00
314_T	317_V	2.259	1.00
183_D	190_S	2.245	1.00
194_C	201_P	2.164	1.00
191_E	195_D	2.149	1.00
188_T	201_P	2.118	1.00
10_F	59_V	2.112	1.00
20_A	432_V	2.107	1.00
237_G	242_L	2.095	1.00
162_T	236_G	2.090	1.00
153_S	169_L	2.084	1.00
324_A	365_A	2.062	1.00
218_A	221_Y	2.043	1.00
330_H	366_H	2.022	1.00
301_N	371_A	1.987	1.00
119_E	122_S	1.986	1.00
5_K	76_I	1.985	1.00
53_Q	95_N	1.971	1.00
65_R	69_R	1.967	1.00
262_T	298_T	1.928	1.00
39_S	54_V	1.928	1.00
363_K	366_H	1.922	1.00
16_N	33_R	1.920	1.00
44_Y	47_S	1.920	1.00
317_V	320_E	1.898	1.00
399_V	410_T	1.892	1.00
332_C	352_F	1.885	1.00
387_T	393_E	1.872	1.00
7_Y	440_N	1.867	1.00
8_L	63_A	1.852	1.00
6_G	29_L	1.842	1.00
219_N	229_I	1.828	1.00
12_I	17_A	1.826	1.00
8_L	19_V	1.806	1.00
166_S	233_V	1.801	1.00
415_D	465_L	1.772	1.00
305_L	371_A	1.765	1.00
380_K	468_Y	1.762	1.00
380_K	469_E	1.752	1.00
138_Y	142_Q	1.740	1.00
91_D	95_N	1.735	1.00
123_S	192_E	1.725	1.00
234_I	442_T	1.720	1.00
119_E	192_E	1.717	1.00
208_V	212_T	1.715	1.00
94_G	163_Y	1.693	1.00
89_L	140_L	1.687	1.00
6_G	21_V	1.665	1.00
119_E	123_S	1.665	1.00
170_T	208_V	1.654	1.00
112_A	116_D	1.652	1.00
213_A	216_T	1.630	1.00
328_E	331_A	1.621	1.00
109_E	113_G	1.599	1.00
213_A	234_I	1.594	1.00
303_Q	307_Q	1.593	1.00
420_K	460_D	1.542	1.00
5_K	74_D	1.528	1.00
88_V	157_I	1.526	1.00
349_R	359_S	1.524	1.00
21_V	70_S	1.521	1.00
321_E	324_A	1.513	1.00
89_L	203_I	1.506	1.00
66_A	70_S	1.505	1.00
472_K	476_R	1.486	1.00
7_Y	445_L	1.480	1.00
321_E	365_A	1.475	1.00
24_V	445_L	1.464	1.00
118_E	122_S	1.462	1.00
56_W	60_M	1.457	1.00
458_P	461_C	1.455	1.00
146_S	149_E	1.454	1.00
322_I	408_A	1.444	1.00
384_D	387_T	1.437	1.00
162_T	214_I	1.437	1.00
30_T	69_R	1.425	1.00
53_Q	57_K	1.420	1.00
369_R	373_E	1.419	1.00
51_S	54_V	1.418	1.00
32_E	62_L	1.409	1.00
139_G	143_R	1.403	1.00
313_E	317_V	1.403	1.00
321_E	364_R	1.397	1.00
32_E	66_A	1.390	1.00
407_K	423_V	1.388	1.00
228_S	231_A	1.387	1.00
440_N	446_T	1.374	1.00
30_T	66_A	1.372	1.00
254_I	396_Y	1.364	1.00
318_M	368_V	1.363	1.00
200_S	203_I	1.359	1.00
67_L	72_D	1.353	1.00
380_K	472_K	1.351	1.00
90_I	155_T	1.349	1.00
396_Y	420_K	1.346	1.00
10_F	63_A	1.345	1.00
320_E	324_A	1.344	1.00
77_G	439_C	1.344	1.00
408_A	412_Y	1.337	1.00
173_P	187_N	1.337	1.00
331_A	470_E	1.335	1.00
319_E	323_S	1.330	1.00
461_C	464_E	1.316	1.00
30_T	70_S	1.315	1.00
216_T	230_N	1.314	1.00
376_A	412_Y	1.314	1.00
84_R	238_G	1.309	1.00
166_S	215_G	1.306	1.00
160_W	164_Q	1.293	1.00
468_Y	472_K	1.290	1.00
376_A	416_L	1.286	1.00
295_P	378_S	1.279	1.00
376_A	413_I	1.278	1.00
119_E	196_I	1.277	1.00
332_C	336_L	1.261	1.00
17_A	59_V	1.257	1.00
194_C	204_L	1.254	1.00
71_C	74_D	1.237	1.00
252_E	269_E	1.237	1.00
57_K	61_N	1.234	1.00
108_R	112_A	1.233	1.00
473_Q	477_F	1.227	1.00
110_W	138_Y	1.226	1.00
41_E	54_V	1.224	1.00
208_V	214_I	1.224	1.00
418_Q	469_E	1.215	1.00
213_A	232_K	1.212	1.00
415_D	462_Q	1.205	1.00
353_L	478_F	1.205	1.00
134_A	197_F	1.201	1.00
405_Q	428_H	1.194	1.00
332_C	371_A	1.192	1.00
17_A	58_Q	1.188	1.00
319_E	407_K	1.187	1.00
49_Y	99_G	1.187	1.00
464_E	467_L	1.186	1.00
237_G	438_I	1.185	1.00
192_E	195_D	1.185	1.00
141_K	148_W	1.184	1.00
380_K	417_L	1.176	1.00
120_I	128_P	1.175	1.00
162_T	170_T	1.174	1.00
168_I	208_V	1.171	1.00
94_G	169_L	1.171	1.00
251_L	254_I	1.169	1.00
51_S	99_G	1.168	1.00
358_L	362_L	1.167	1.00
144_Q	147_L	1.165	1.00
412_Y	416_L	1.162	1.00
32_E	69_R	1.158	1.00
297_I	301_N	1.156	1.00
89_L	151_T	1.152	1.00
255_V	394_R	1.148	1.00
10_F	19_V	1.147	1.00
309_F	367_F	1.141	1.00
319_E	406_S	1.139	1.00
151_T	203_I	1.131	1.00
297_I	300_L	1.127	1.00
61_N	65_R	1.126	1.00
173_P	207_L	1.125	1.00
112_A	115_P	1.124	1.00
146_S	150_K	1.124	1.00
279_W	282_C	1.116	1.00
22_V	28_V	1.116	1.00
362_L	366_H	1.111	1.00
317_V	321_E	1.109	1.00
441_E	452_N	1.109	1.00
111_E	128_P	1.103	1.00
5_K	24_V	1.103	1.00
213_A	442_T	1.102	1.00
155_T	169_L	1.099	1.00
170_T	214_I	1.099	1.00
384_D	472_K	1.092	1.00
6_G	74_D	1.091	1.00
398_W	422_Y	1.090	1.00
77_G	443_F	1.088	1.00
316_E	319_E	1.082	1.00
109_E	112_A	1.081	1.00
332_C	370_A	1.080	1.00
148_W	151_T	1.078	1.00
301_N	332_C	1.077	1.00
89_L	137_L	1.075	1.00
59_V	161_V	1.074	1.00
7_Y	443_F	1.073	1.00
320_E	323_S	1.072	1.00
22_V	436_A	1.061	1.00
270_D	286_Q	1.059	1.00
67_L	70_S	1.058	1.00
106_R	139_G	1.054	1.00
173_P	182_F	1.044	1.00
65_R	68_S	1.043	1.00
98_L	147_L	1.038	1.00
321_E	368_V	1.037	1.00
251_L	450_S	1.035	1.00
55_L	157_I	1.034	1.00
254_I	398_W	1.024	1.00
80_S	162_T	1.023	1.00
52_P	88_V	1.021	1.00
418_Q	465_L	1.019	1.00
110_W	113_G	1.011	1.00
137_L	154_F	1.010	1.00
383_F	417_L	1.006	1.00
279_W	284_T	1.005	1.00
40_T	50_F	1.001	1.00
59_V	63_A	0.994	1.00
194_C	199_F	0.994	1.00
375_I	403_G	0.993	1.00
54_V	57_K	0.993	1.00
377_F	416_L	0.991	1.00
110_W	143_R	0.989	1.00
269_E	288_H	0.986	1.00
274_T	277_K	0.985	1.00
38_Y	58_Q	0.982	1.00
469_E	473_Q	0.980	1.00
120_I	180_L	0.979	1.00
134_A	180_L	0.977	1.00
216_T	232_K	0.975	1.00
163_Y	169_L	0.972	1.00
28_V	31_V	0.971	1.00
473_Q	476_R	0.971	1.00
470_E	473_Q	0.969	1.00
369_R	408_A	0.968	1.00
64_K	68_S	0.960	1.00
446_T	452_N	0.958	1.00
187_N	209_R	0.957	1.00
7_Y	77_G	0.956	1.00
77_G	234_I	0.954	1.00
78_L	231_A	0.951	1.00
471_W	474_T	0.949	1.00
145_P	149_E	0.949	1.00
48_R	103_I	0.949	1.00
325_L	330_H	0.945	1.00
19_V	66_A	0.944	1.00
81_T	431_S	0.944	1.00
89_L	154_F	0.944	1.00
95_N	164_Q	0.942	1.00
279_W	283_H	0.941	1.00
450_S	453_V	0.938	1.00
403_G	409_L	0.938	1.00
21_V	75_I	0.933	1.00
147_L	150_K	0.932	1.00
437_V	452_N	0.932	1.00
281_N	284_T	0.930	1.00
255_V	266_K	0.930	1.00
182_F	186_Q	0.929	1.00
410_T	459_K	0.925	1.00
22_V	433_V	0.925	1.00
76_I	443_F	0.923	1.00
234_I	443_F	0.922	1.00
151_T	154_F	0.921	1.00
440_N	445_L	0.918	1.00
323_S	408_A	0.916	1.00
8_L	21_V	0.915	1.00
251_L	453_V	0.915	1.00
380_K	416_L	0.913	1.00
159_D	171_Y	0.904	1.00
23_S	29_L	0.902	1.00
377_F	471_W	0.900	1.00
140_L	147_L	0.897	1.00
315_Y	318_M	0.896	1.00
350_G	358_L	0.895	1.00
167_G	218_A	0.892	1.00
264_I	383_F	0.892	1.00
471_W	475_Q	0.891	1.00
466_A	470_E	0.890	1.00
8_L	75_I	0.890	1.00
80_S	161_V	0.887	1.00
60_M	64_K	0.886	1.00
358_L	367_F	0.886	1.00
173_P	209_R	0.882	1.00
325_L	328_E	0.881	1.00
397_V	417_L	0.879	1.00
251_L	454_R	0.877	1.00
122_S	185_K	0.876	1.00
208_V	235_A	0.875	1.00
98_L	140_L	0.875	1.00
441_E	449_M	0.875	1.00
67_L	75_I	0.874	1.00
455_V	458_P	0.874	1.00
352_F	371_A	0.873	1.00
79_T	234_I	0.871	1.00
134_A	181_L	0.870	1.00
80_S	165_L	0.869	1.00
417_L	420_K	0.868	1.00
138_Y	141_K	0.866	1.00
441_E	448_E	0.865	1.00
171_Y	176_A	0.865	1.00
384_D	388_E	0.865	1.00
467_L	471_W	0.862	1.00
312_N	318_M	0.862	1.00
274_T	278_A	0.861	1.00
75_I	231_A	0.860	1.00
253_D	395_D	0.859	1.00
467_L	470_E	0.857	1.00
87_I	154_F	0.856	1.00
468_Y	471_W	0.856	1.00
12_I	161_V	0.854	1.00
267_I	288_H	0.851	1.00
262_T	379_I	0.851	1.00
460_D	465_L	0.850	1.00
474_T	477_F	0.846	1.00
310_Y	364_R	0.846	1.00
322_I	369_R	0.846	1.00
73_I	228_S	0.845	1.00
407_K	459_K	0.843	1.00
420_K	457_E	0.840	1.00
90_I	94_G	0.840	1.00
273_D	277_K	0.838	1.00
266_K	386_L	0.834	1.00
263_P	294_N	0.833	1.00
122_S	273_D	0.832	1.00
188_T	206_P	0.832	1.00
316_E	320_E	0.831	1.00
189_W	204_L	0.829	1.00
187_N	287_G	0.829	1.00
170_T	206_P	0.829	1.00
217_I	231_A	0.829	1.00
34_E	62_L	0.827	1.00
85_Q	178_E	0.824	1.00
37_E	306_K	0.822	1.00
115_P	128_P	0.822	1.00
256_I	413_I	0.822	1.00
105_N	129_T	0.821	1.00
113_G	116_D	0.820	1.00
372_L	412_Y	0.818	1.00
152_A	202_S	0.818	1.00
109_E	143_R	0.813	1.00
451_A	454_R	0.813	1.00
111_E	130_A	0.810	1.00
243_A	400_C	0.808	1.00
54_V	58_Q	0.808	1.00
37_E	303_Q	0.808	1.00
137_L	181_L	0.806	1.00
111_E	135_L	0.804	1.00
84_R	175_Q	0.803	1.00
383_F	387_T	0.802	1.00
188_T	191_E	0.801	1.00
171_Y	205_P	0.801	1.00
182_F	187_N	0.796	1.00
84_R	292_E	0.794	1.00
113_G	138_Y	0.792	1.00
328_E	373_E	0.792	1.00
399_V	423_V	0.789	1.00
351_G	478_F	0.787	1.00
306_K	315_Y	0.786	1.00
97_F	150_K	0.786	1.00
348_T	351_G	0.786	1.00
463_I	466_A	0.785	1.00
399_V	413_I	0.782	1.00
470_E	474_T	0.780	1.00
219_N	230_N	0.780	1.00
156_S	179_T	0.779	1.00
240_T	263_P	0.779	1.00
177_T	282_C	0.778	1.00
404_F	428_H	0.777	1.00
440_N	444_Q	0.775	1.00
171_Y	207_L	0.775	1.00
251_L	395_D	0.775	1.00
76_I	445_L	0.775	1.00
158_S	236_G	0.774	1.00
280_L	283_H	0.774	1.00
258_S	413_I	0.771	1.00
63_A	67_L	0.770	1.00
327_K	467_L	0.768	1.00
216_T	229_I	0.766	1.00
60_M	221_Y	0.766	1.00
176_A	189_W	0.765	1.00
325_L	329_D	0.765	1.00
174_S	284_T	0.760	1.00
273_D	276_H	0.760	1.00
466_A	469_E	0.760	1.00
304_K	307_Q	0.759	1.00
313_E	364_R	0.757	1.00
9_V	79_T	0.757	1.00
322_I	368_V	0.755	1.00
385_I	388_E	0.755	1.00
109_E	142_Q	0.755	1.00
325_L	365_A	0.755	1.00
52_P	99_G	0.755	1.00
249_A	254_I	0.754	1.00
12_I	59_V	0.753	1.00
91_D	97_F	0.752	1.00
192_E	196_I	0.747	1.00
247_T	400_C	0.747	1.00
138_Y	198_G	0.745	1.00
89_L	97_F	0.741	1.00
319_E	408_A	0.741	1.00
298_T	375_I	0.741	1.00
323_S	411_Q	0.738	1.00
376_A	409_L	0.734	1.00
268_T	291_V	0.734	1.00
372_L	406_S	0.732	1.00
43_L	47_S	0.732	1.00
102_N	261_T	0.731	1.00
92_Q	150_K	0.731	1.00
404_F	410_T	0.730	1.00
14_T	101_P	0.730	1.00
59_V	62_L	0.730	1.00
381_W	476_R	0.728	1.00
78_L	217_I	0.727	1.00
34_E	58_Q	0.727	1.00
305_L	367_F	0.726	1.00
90_I	169_L	0.725	1.00
217_I	228_S	0.724	1.00
123_S	183_D	0.723	1.00
227_L	230_N	0.723	1.00
243_A	431_S	0.722	1.00
305_L	368_V	0.721	1.00
280_L	284_T	0.721	1.00
77_G	232_K	0.711	1.00
469_E	472_K	0.711	1.00
399_V	421_V	0.711	1.00
57_K	60_M	0.708	1.00
460_D	463_I	0.707	1.00
31_V	429_Q	0.705	1.00
326_A	329_D	0.705	1.00
60_M	164_Q	0.703	1.00
448_E	452_N	0.703	1.00
53_Q	160_W	0.702	1.00
255_V	397_V	0.702	1.00
72_D	75_I	0.700	1.00
91_D	152_A	0.697	1.00
174_S	237_G	0.697	1.00
303_Q	315_Y	0.696	1.00
112_A	347_L	0.693	1.00
38_Y	50_F	0.692	1.00
377_F	468_Y	0.691	1.00
53_Q	96_P	0.691	1.00
217_I	227_L	0.690	1.00
293_T	382_N	0.689	1.00
120_I	193_M	0.687	1.00
124_T	193_M	0.687	1.00
229_I	232_K	0.686	0.99
323_S	407_K	0.684	0.99
12_I	58_Q	0.684	0.99
406_S	409_L	0.684	0.99
385_I	389_V	0.679	0.99
63_A	66_A	0.679	0.99
162_T	166_S	0.679	0.99
94_G	152_A	0.679	0.99
239_D	260_T	0.678	0.99
183_D	188_T	0.678	0.99
397_V	419_K	0.677	0.99
20_A	28_V	0.676	0.99
216_T	219_N	0.675	0.99
7_Y	76_I	0.675	0.99
210_A	236_G	0.675	0.99
327_K	330_H	0.673	0.99
87_I	133_S	0.672	0.99
149_E	153_S	0.672	0.99
114_I	197_F	0.670	0.99
322_I	325_L	0.670	0.99
214_I	235_A	0.669	0.99
160_W	163_Y	0.668	0.99
227_L	231_A	0.668	0.99
53_Q	99_G	0.667	0.99
327_K	331_A	0.667	0.99
381_W	472_K	0.666	0.99
257_V	379_I	0.666	0.99
49_Y	106_R	0.664	0.99
61_N	64_K	0.664	0.99
82_S	175_Q	0.664	0.99
100_L	106_R	0.663	0.99
411_Q	459_K	0.662	0.99
418_Q	463_I	0.662	0.99
90_I	160_W	0.661	0.99
190_S	193_M	0.659	0.99
449_M	452_N	0.657	0.99
118_E	121_Y	0.654	0.99
328_E	369_R	0.654	0.99
90_I	153_S	0.652	0.99
384_D	476_R	0.650	0.99
295_P	382_N	0.649	0.99
373_E	412_Y	0.647	0.99
262_T	413_I	0.646	0.99
24_V	76_I	0.646	0.99
221_Y	230_N	0.646	0.99
335_A	339_Y	0.645	0.99
407_K	411_Q	0.645	0.99
472_K	475_Q	0.644	0.99
437_V	441_E	0.643	0.99
397_V	421_V	0.643	0.99
138_Y	197_F	0.642	0.99
22_V	432_V	0.642	0.99
465_L	468_Y	0.639	0.99
141_K	198_G	0.636	0.99
60_M	63_A	0.635	0.99
90_I	163_Y	0.635	0.99
395_D	419_K	0.634	0.99
321_E	325_L	0.634	0.99
246_S	430_A	0.631	0.99
265_T	290_L	0.629	0.99
326_A	330_H	0.628	0.99
302_Y	319_E	0.627	0.99
396_Y	419_K	0.626	0.99
6_G	70_S	0.626	0.99
82_S	157_I	0.624	0.99
369_R	412_Y	0.623	0.99
56_W	221_Y	0.623	0.99
305_L	309_F	0.622	0.99
158_S	175_Q	0.622	0.99
319_E	322_I	0.621	0.99
394_R	419_K	0.619	0.99
185_K	271_H	0.619	0.99
193_M	197_F	0.618	0.99
174_S	210_A	0.618	0.99
357_P	362_L	0.616	0.99
359_S	362_L	0.614	0.99
181_L	204_L	0.612	0.99
100_L	140_L	0.612	0.99
150_K	153_S	0.611	0.99
410_T	423_V	0.611	0.99
244_V	283_H	0.608	0.99
213_A	443_F	0.607	0.99
39_S	51_S	0.607	0.99
343_E	381_W	0.606	0.99
135_L	180_L	0.605	0.99
51_S	57_K	0.605	0.99
53_Q	56_W	0.605	0.99
83_Q	102_N	0.602	0.99
461_C	475_Q	0.602	0.99
187_N	282_C	0.602	0.99
448_E	454_R	0.600	0.99
311_P	364_R	0.600	0.99
238_G	241_Q	0.600	0.99
137_L	203_I	0.599	0.99
138_Y	148_W	0.598	0.99
343_E	348_T	0.598	0.99
281_N	290_L	0.597	0.99
232_K	443_F	0.594	0.99
107_G	135_L	0.592	0.99
331_A	369_R	0.592	0.99
290_L	294_N	0.591	0.99
375_I	409_L	0.591	0.99
262_T	295_P	0.590	0.98
114_I	135_L	0.590	0.98
7_Y	446_T	0.590	0.98
195_D	200_S	0.588	0.98
148_W	152_A	0.588	0.98
179_T	189_W	0.584	0.98
345_N	348_T	0.583	0.98
49_Y	98_L	0.583	0.98
6_G	73_I	0.582	0.98
128_P	180_L	0.582	0.98
373_E	377_F	0.581	0.98
245_K	437_V	0.581	0.98
299_G	303_Q	0.580	0.98
108_R	130_A	0.580	0.98
256_I	264_I	0.580	0.98
221_Y	227_L	0.577	0.98
257_V	413_I	0.577	0.98
450_S	454_R	0.576	0.98
296_G	340_L	0.576	0.98
441_E	446_T	0.573	0.98
75_I	227_L	0.573	0.98
78_L	233_V	0.573	0.98
159_D	169_L	0.572	0.98
415_D	459_K	0.572	0.98
84_R	178_E	0.572	0.98
15_G	18_R	0.571	0.98
126_R	132_F	0.570	0.98
276_H	389_V	0.570	0.98
333_V	351_G	0.567	0.98
211_G	442_T	0.567	0.98
132_F	178_E	0.567	0.98
206_P	212_T	0.567	0.98
254_I	395_D	0.566	0.98
185_K	273_D	0.565	0.98
248_G	453_V	0.565	0.98
298_T	301_N	0.563	0.98
460_D	464_E	0.563	0.98
7_Y	24_V	0.563	0.98
88_V	96_P	0.562	0.98
423_V	459_K	0.561	0.98
266_K	394_R	0.561	0.98
273_D	278_A	0.559	0.98
218_A	230_N	0.559	0.98
85_Q	102_N	0.558	0.98
322_I	372_L	0.558	0.98
315_Y	319_E	0.558	0.98
173_P	210_A	0.557	0.98
404_F	423_V	0.556	0.98
411_Q	414_A	0.554	0.98
319_E	372_L	0.553	0.98
441_E	444_Q	0.552	0.98
407_K	457_E	0.552	0.98
245_K	284_T	0.552	0.98
29_L	33_R	0.550	0.98
423_V	456_I	0.549	0.98
303_Q	306_K	0.546	0.98
94_G	153_S	0.545	0.97
300_L	303_Q	0.545	0.97
96_P	99_G	0.544	0.97
456_I	461_C	0.544	0.97
193_M	196_I	0.542	0.97
155_T	163_Y	0.542	0.97
310_Y	313_E	0.542	0.97
199_F	204_L	0.542	0.97
50_F	101_P	0.542	0.97
413_I	417_L	0.541	0.97
211_G	441_E	0.538	0.97
433_V	437_V	0.538	0.97
210_A	237_G	0.537	0.97
14_T	102_N	0.537	0.97
244_V	265_T	0.537	0.97
48_R	101_P	0.537	0.97
20_A	433_V	0.536	0.97
332_C	374_E	0.536	0.97
325_L	369_R	0.536	0.97
195_D	201_P	0.535	0.97
167_G	220_E	0.534	0.97
326_A	369_R	0.534	0.97
330_H	361_H	0.533	0.97
106_R	143_R	0.532	0.97
449_M	453_V	0.532	0.97
95_N	150_K	0.531	0.97
377_F	380_K	0.530	0.97
278_A	282_C	0.530	0.97
327_K	369_R	0.530	0.97
156_S	175_Q	0.529	0.97
437_V	449_M	0.528	0.97
357_P	360_A	0.526	0.97
62_L	66_A	0.526	0.97
336_L	358_L	0.525	0.97
5_K	445_L	0.525	0.97
130_A	346_A	0.525	0.97
395_D	420_K	0.524	0.97
86_G	101_P	0.524	0.97
308_I	363_K	0.523	0.97
272_G	275_K	0.522	0.97
117_W	121_Y	0.522	0.97
273_D	280_L	0.522	0.97
407_K	456_I	0.521	0.97
318_M	408_A	0.521	0.97
334_A	374_E	0.521	0.97
432_V	435_A	0.521	0.97
120_I	197_F	0.521	0.97
414_A	421_V	0.521	0.97
377_F	467_L	0.521	0.97
379_I	413_I	0.519	0.97
195_D	198_G	0.519	0.97
387_T	391_P	0.519	0.97
97_F	151_T	0.518	0.97
24_V	440_N	0.518	0.97
264_I	382_N	0.517	0.97
47_S	106_R	0.517	0.97
27_S	425_E	0.516	0.97
198_G	201_P	0.515	0.96
217_I	226_G	0.514	0.96
216_T	231_A	0.514	0.96
185_K	188_T	0.514	0.96
305_L	310_Y	0.512	0.96
448_E	453_V	0.511	0.96
81_T	435_A	0.510	0.96
85_Q	261_T	0.509	0.96
282_C	289_W	0.507	0.96
260_T	300_L	0.507	0.96
83_Q	238_G	0.503	0.96
174_S	241_Q	0.503	0.96
294_N	340_L	0.503	0.96
239_D	259_G	0.503	0.96
258_S	403_G	0.502	0.96
158_S	171_Y	0.502	0.96
446_T	451_A	0.500	0.96

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ll3A	2	0.9774	100	0.154	Contact Map
3qdkA	2	0.9733	100	0.159	Contact Map
2itmA	2	0.9528	100	0.161	Contact Map
3ifrA	2	0.9671	100	0.17	Contact Map
3hz6A	1	0.9713	100	0.171	Contact Map
3h3nX	3	0.9774	100	0.177	Contact Map
3ezwA	3	0.9774	100	0.18	Contact Map
3wxlA	2	0.9836	100	0.182	Contact Map
3g25A	3	0.9754	100	0.183	Contact Map
2w40A	3	0.9733	100	0.187	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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