RSBRB - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

RSBRB - RsbT co-antagonist protein RsbRB

UniProt:	O34860	Sequences: MKLNEKLYAFFSEHVEQMAEEWIETMEESDPNSLYALHNATVTEELKEQDREFYRHLNYMYVLPEKQFLEEFQEWVIELTNDQKHLDTPVQYVIREFMRNRRLYTKYFEKFAEENESAFEPGEKQKWADLIVKVFDFTIYTFVDHAEMNAKQQLNAQREMILELSSPVITLSKSTALLPLVGDIDTERAKFILENTLQACAKRRVEHLLIDLSGVVVVDTMVAHQIFKLIEALNLIGVRSTLSGIRPEIAQTAVQLGIDFSNITIKTNLAQALNYHQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	277 (258)
Sequences:	915 (741)
Seq/√Len:	46.1

BACSU - RSBRB RSBRC RSBRD RSBRA RSBS

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
101_R	136_D	5.476	1.00
14_H	17_Q	5.365	1.00
220_T	252_T	4.288	1.00
9_A	13_E	3.648	1.00
212_L	218_V	3.505	1.00
197_L	232_A	3.432	1.00
20_E	24_E	3.142	1.00
243_S	272_A	3.135	1.00
161_I	169_I	2.875	1.00
184_I	189_A	2.769	1.00
186_T	217_V	2.546	1.00
186_T	221_M	2.500	1.00
170_T	177_L	2.324	1.00
21_E	106_K	2.281	1.00
252_T	256_L	2.164	1.00
176_A	205_V	2.123	1.00
223_A	252_T	2.048	0.99
199_A	202_K	2.036	0.99
184_I	192_I	2.029	0.99
43_T	47_K	2.008	0.99
208_L	213_S	1.983	0.99
220_T	256_L	1.955	0.99
246_R	257_G	1.933	0.99
98_M	139_I	1.885	0.99
176_A	200_C	1.870	0.99
196_T	208_L	1.844	0.99
208_L	238_V	1.830	0.99
220_T	257_G	1.804	0.99
106_K	129_D	1.776	0.98
220_T	223_A	1.762	0.98
14_H	107_Y	1.740	0.98
222_V	250_A	1.705	0.98
56_H	60_M	1.702	0.98
200_C	233_L	1.694	0.98
210_I	233_L	1.656	0.98
146_A	149_N	1.656	0.98
218_V	249_I	1.655	0.98
186_T	215_V	1.643	0.97
230_I	242_L	1.628	0.97
213_S	233_L	1.619	0.97
154_L	157_Q	1.598	0.97
198_Q	202_K	1.595	0.97
215_V	249_I	1.565	0.97
166_S	192_I	1.543	0.96
174_S	206_E	1.540	0.96
220_T	224_H	1.529	0.96
23_I	26_M	1.515	0.96
7_L	15_V	1.512	0.96
102_R	133_K	1.512	0.96
186_T	190_K	1.510	0.96
205_V	213_S	1.510	0.96
173_K	270_A	1.496	0.96
253_A	260_F	1.485	0.95
224_H	228_K	1.480	0.95
219_D	222_V	1.435	0.94
157_Q	169_I	1.422	0.94
21_E	25_T	1.420	0.94
164_L	185_D	1.420	0.94
143_V	147_E	1.395	0.94
245_I	250_A	1.390	0.93
228_K	233_L	1.385	0.93
152_Q	156_A	1.380	0.93
207_H	241_T	1.377	0.93
10_F	111_F	1.367	0.93
215_V	252_T	1.356	0.93
243_S	270_A	1.349	0.92
25_T	102_R	1.349	0.92
15_V	19_A	1.346	0.92
141_T	145_H	1.330	0.92
177_L	196_T	1.323	0.92
76_V	138_T	1.318	0.91
111_F	114_E	1.316	0.91
253_A	258_I	1.299	0.91
172_S	243_S	1.293	0.91
186_T	220_T	1.293	0.91
163_E	220_T	1.285	0.90
178_L	213_S	1.284	0.90
217_V	220_T	1.283	0.90
173_K	204_R	1.234	0.88
209_L	243_S	1.229	0.88
215_V	256_L	1.211	0.88
213_S	238_V	1.204	0.87
135_F	139_I	1.198	0.87
17_Q	20_E	1.193	0.87
239_R	264_T	1.191	0.87
44_E	48_E	1.191	0.87
168_V	219_D	1.183	0.86
109_E	126_K	1.175	0.86
57_L	78_E	1.175	0.86
168_V	257_G	1.163	0.85
206_E	210_I	1.163	0.85
21_E	107_Y	1.162	0.85
219_D	250_A	1.160	0.85
234_N	239_R	1.157	0.85
209_L	269_L	1.155	0.85
213_S	272_A	1.148	0.85
180_L	222_V	1.148	0.85
84_K	132_V	1.129	0.84
108_F	173_K	1.120	0.83
186_T	225_Q	1.111	0.83
158_R	231_E	1.107	0.82
172_S	177_L	1.102	0.82
193_L	232_A	1.100	0.82
59_Y	63_L	1.099	0.82
43_T	53_F	1.094	0.82
186_T	222_V	1.088	0.81
17_Q	27_E	1.086	0.81
13_E	24_E	1.084	0.81
180_L	208_L	1.060	0.79
259_D	262_N	1.057	0.79
42_V	52_E	1.053	0.79
164_L	246_R	1.051	0.79
12_S	17_Q	1.051	0.79
75_W	233_L	1.051	0.79
266_K	275_Y	1.050	0.79
218_V	222_V	1.048	0.79
48_E	273_L	1.046	0.79
249_I	252_T	1.040	0.78
188_R	250_A	1.039	0.78
169_I	246_R	1.031	0.78
189_A	225_Q	1.028	0.77
43_T	146_A	1.025	0.77
14_H	44_E	1.020	0.77
46_L	49_Q	1.012	0.76
160_M	169_I	1.004	0.76
228_K	254_V	1.000	0.75
150_A	153_Q	0.990	0.75
212_L	229_L	0.983	0.74
31_P	42_V	0.983	0.74
9_A	12_S	0.981	0.74
184_I	249_I	0.980	0.74
180_L	233_L	0.979	0.74
105_T	128_A	0.976	0.74
21_E	24_E	0.973	0.73
229_L	238_V	0.971	0.73
11_F	47_K	0.967	0.73
182_G	211_D	0.961	0.72
243_S	273_L	0.960	0.72
10_F	28_E	0.958	0.72
243_S	275_Y	0.958	0.72
23_I	28_E	0.954	0.72
264_T	267_T	0.948	0.71
203_R	274_N	0.947	0.71
10_F	31_P	0.947	0.71
163_E	186_T	0.939	0.71
26_M	50_D	0.936	0.70
109_E	114_E	0.936	0.70
153_Q	161_I	0.933	0.70
212_L	243_S	0.918	0.69
14_H	110_K	0.916	0.69
194_E	219_D	0.911	0.68
11_F	18_M	0.911	0.68
178_L	272_A	0.910	0.68
41_T	45_E	0.909	0.68
58_N	61_Y	0.902	0.67
181_V	214_G	0.899	0.67
213_S	229_L	0.896	0.67
132_V	136_D	0.892	0.67
200_C	205_V	0.892	0.67
16_E	21_E	0.886	0.66
20_E	47_K	0.883	0.66
78_E	126_K	0.880	0.66
209_L	242_L	0.879	0.65
160_M	181_V	0.879	0.65
17_Q	21_E	0.875	0.65
72_F	135_F	0.869	0.65
31_P	44_E	0.867	0.64
91_Q	147_E	0.864	0.64
90_V	144_D	0.863	0.64
21_E	110_K	0.861	0.64
185_D	193_L	0.856	0.63
74_E	110_K	0.851	0.63
96_E	99_R	0.851	0.63
43_T	61_Y	0.851	0.63
115_N	118_A	0.845	0.62
150_A	154_L	0.843	0.62
173_K	273_L	0.842	0.62
231_E	273_L	0.841	0.62
7_L	102_R	0.839	0.62
40_A	50_D	0.839	0.62
10_F	18_M	0.837	0.62
212_L	215_V	0.831	0.61
51_R	55_R	0.831	0.61
217_V	252_T	0.826	0.61
53_F	57_L	0.825	0.60
194_E	269_L	0.823	0.60
107_Y	148_M	0.823	0.60
11_F	105_T	0.811	0.59
176_A	233_L	0.810	0.59
80_T	93_V	0.808	0.59
151_K	155_N	0.806	0.59
148_M	152_Q	0.804	0.58
111_F	115_N	0.801	0.58
227_F	249_I	0.797	0.58
212_L	253_A	0.797	0.58
199_A	213_S	0.795	0.58
104_Y	111_F	0.795	0.58
7_L	12_S	0.789	0.57
27_E	30_D	0.789	0.57
181_V	255_Q	0.788	0.57
12_S	62_V	0.782	0.56
58_N	74_E	0.781	0.56
196_T	229_L	0.779	0.56
159_E	187_E	0.779	0.56
19_A	23_I	0.778	0.56
170_T	271_Q	0.775	0.56
209_L	213_S	0.774	0.56
226_I	260_F	0.772	0.55
220_T	247_P	0.771	0.55
186_T	236_I	0.770	0.55
12_S	29_S	0.769	0.55
93_V	142_F	0.768	0.55
55_R	268_N	0.767	0.55
178_L	212_L	0.767	0.55
163_E	189_A	0.766	0.55
15_V	51_R	0.766	0.55
232_A	269_L	0.766	0.55
227_F	253_A	0.765	0.55
221_M	252_T	0.764	0.55
207_H	267_T	0.759	0.54
50_D	60_M	0.759	0.54
196_T	205_V	0.759	0.54
57_L	84_K	0.757	0.54
237_G	244_G	0.756	0.54
97_F	139_I	0.755	0.54
200_C	208_L	0.754	0.54
176_A	271_Q	0.753	0.54
147_E	161_I	0.748	0.53
252_T	257_G	0.748	0.53
232_A	268_N	0.747	0.53
20_E	31_P	0.745	0.53
189_A	220_T	0.745	0.53
142_F	160_M	0.744	0.53
20_E	38_H	0.740	0.52
189_A	221_M	0.738	0.52
110_K	126_K	0.736	0.52
20_E	25_T	0.733	0.52
94_I	139_I	0.733	0.52
21_E	28_E	0.732	0.51
22_W	157_Q	0.730	0.51
171_L	233_L	0.730	0.51
176_A	203_R	0.729	0.51
223_A	258_I	0.727	0.51
159_E	206_E	0.727	0.51
249_I	256_L	0.724	0.51
199_A	203_R	0.722	0.51
23_I	50_D	0.720	0.50
7_L	10_F	0.719	0.50
23_I	43_T	0.719	0.50
52_E	78_E	0.719	0.50
9_A	16_E	0.718	0.50
68_F	202_K	0.716	0.50
159_E	162_L	0.714	0.50
251_Q	254_V	0.712	0.50
25_T	103_L	0.709	0.49
212_L	249_I	0.708	0.49
196_T	216_V	0.707	0.49
98_M	140_Y	0.705	0.49
249_I	257_G	0.704	0.49
12_S	67_Q	0.700	0.48
136_D	142_F	0.699	0.48
135_F	246_R	0.693	0.48
29_S	206_E	0.693	0.48
53_F	56_H	0.690	0.47
9_A	24_E	0.688	0.47
155_N	159_E	0.685	0.47
242_L	272_A	0.685	0.47
233_L	238_V	0.685	0.47
140_Y	200_C	0.678	0.46
163_E	187_E	0.678	0.46
157_Q	163_E	0.676	0.46
156_A	251_Q	0.675	0.46
175_T	228_K	0.675	0.46
222_V	256_L	0.671	0.45
176_A	231_E	0.665	0.45
12_S	59_Y	0.665	0.45
13_E	110_K	0.663	0.45
39_N	42_V	0.660	0.44
222_V	257_G	0.660	0.44
114_E	184_I	0.659	0.44
46_L	61_Y	0.656	0.44
158_R	187_E	0.655	0.44
220_T	258_I	0.654	0.44
14_H	20_E	0.654	0.44
56_H	83_Q	0.653	0.44
52_E	56_H	0.652	0.44
181_V	249_I	0.649	0.43
161_I	164_L	0.648	0.43
20_E	28_E	0.648	0.43
113_E	116_E	0.647	0.43
15_V	31_P	0.646	0.43
109_E	129_D	0.643	0.43
26_M	96_E	0.642	0.43
215_V	222_V	0.636	0.42
103_L	171_L	0.636	0.42
58_N	106_K	0.634	0.42
221_M	246_R	0.632	0.42
193_L	243_S	0.630	0.42
74_E	112_A	0.627	0.41
19_A	26_M	0.625	0.41
186_T	227_F	0.625	0.41
81_N	171_L	0.624	0.41
78_E	152_Q	0.623	0.41
112_A	116_E	0.622	0.41
219_D	223_A	0.620	0.41
178_L	208_L	0.619	0.40
192_I	271_Q	0.617	0.40
177_L	229_L	0.615	0.40
186_T	189_A	0.611	0.40
184_I	251_Q	0.609	0.40
39_N	43_T	0.608	0.39
49_Q	82_D	0.607	0.39
70_E	81_N	0.607	0.39
90_V	171_L	0.603	0.39
221_M	255_Q	0.600	0.39
54_Y	59_Y	0.599	0.39
16_E	20_E	0.597	0.38
18_M	27_E	0.593	0.38
210_I	239_R	0.591	0.38
61_Y	111_F	0.589	0.38
161_I	208_L	0.586	0.37
165_S	220_T	0.582	0.37
231_E	255_Q	0.582	0.37
195_N	243_S	0.581	0.37
11_F	48_E	0.581	0.37
168_V	199_A	0.579	0.37
113_E	180_L	0.579	0.37
189_A	230_I	0.577	0.37
189_A	193_L	0.575	0.36
20_E	23_I	0.574	0.36
207_H	232_A	0.571	0.36
211_D	237_G	0.571	0.36
196_T	200_C	0.569	0.36
220_T	227_F	0.568	0.36
77_I	113_E	0.567	0.36
124_K	128_A	0.566	0.36
101_R	104_Y	0.564	0.35
15_V	55_R	0.562	0.35
14_H	28_E	0.561	0.35
87_D	146_A	0.560	0.35
163_E	227_F	0.557	0.35
67_Q	71_E	0.557	0.35
211_D	244_G	0.556	0.35
22_W	76_V	0.555	0.35
72_F	136_D	0.554	0.34
23_I	79_L	0.554	0.34
15_V	112_A	0.551	0.34
98_M	146_A	0.551	0.34
182_G	237_G	0.550	0.34
133_K	168_V	0.547	0.34
249_I	254_V	0.547	0.34
177_L	184_I	0.545	0.34
18_M	30_D	0.540	0.33
83_Q	92_Y	0.540	0.33
241_T	275_Y	0.536	0.33
61_Y	242_L	0.535	0.33
182_G	244_G	0.535	0.33
48_E	109_E	0.535	0.33
236_I	242_L	0.535	0.33
18_M	28_E	0.532	0.33
103_L	106_K	0.532	0.33
215_V	218_V	0.531	0.32
174_S	205_V	0.530	0.32
176_A	236_I	0.530	0.32
52_E	258_I	0.528	0.32
227_F	238_V	0.528	0.32
186_T	252_T	0.526	0.32
107_Y	111_F	0.525	0.32
249_I	272_A	0.522	0.32
47_K	91_Q	0.521	0.32
16_E	116_E	0.521	0.32
23_I	27_E	0.520	0.32
51_R	63_L	0.518	0.31
205_V	212_L	0.516	0.31
49_Q	79_L	0.516	0.31
212_L	232_A	0.515	0.31
236_I	253_A	0.511	0.31
251_Q	261_S	0.510	0.31
19_A	54_Y	0.510	0.31
8_Y	12_S	0.510	0.31
16_E	28_E	0.509	0.31
117_S	133_K	0.509	0.31
12_S	30_D	0.508	0.31
106_K	115_N	0.503	0.30
30_D	55_R	0.503	0.30
149_N	152_Q	0.501	0.30
112_A	118_A	0.500	0.30

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3zxnA	1	0.4079	99.6	0.752	Contact Map
4dgfA	1	0.4224	99.3	0.803	Contact Map
3ny7A	1	0.4188	99.3	0.803	Contact Map
1h4xA	1	0.4007	99.1	0.815	Contact Map
1th8B	1	0.4043	99.1	0.816	Contact Map
3t6oA	5	0.3971	99.1	0.817	Contact Map
2ka5A	1	0.444	99.1	0.819	Contact Map
4dghA	4	0.4332	99	0.82	Contact Map
3lloA	1	0.4477	99	0.82	Contact Map
2klnA	1	0.426	99	0.822	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.009 seconds.