ARLY - BACSU - GREMLIN Contacts

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ARLY - Argininosuccinate lyase

UniProt:	O34858	Sequences: MKKLWGGRFQKTPEKWVDEFGASISFDQNLVAEDITGSLAHAAMLKKCGILTAEEELKIREGLNTLLQKAEEGALEFSVDYEDIHLNIEKMLIDEIGPLGGKLHTGRSRNDQVATDMHLYLKNHVGHIIELIEAFQSALIEKAEANVETILPGYTHLQRAQPISFAHHLLAYFWMLERDKERFQDSMKRINKSPLGCGALAGTTFPIDRDYSAELLGFDAIYENSLDGVSDRDFILEFLSNSSMLMMHLSRFSEEIILWCSQEFKFIELDDTYATGSSMMPQKKNPDMAELIRGKTGRVYGDMMGLFTIMKGLPLAYNKDLQEDKEGMFDTVKTVEGSLQIFTGMIQTMTVNKDVMKQATKQDFSNATELADYLAKKGMPFREAHEVVGKLVYTCIERGIYLSDMPFGEFQQASTLFEEDIYTVLDPYYAVEKRMSAGGTGFKQVEQALEKAKACVAAGVC	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	461 (406)
Sequences:	10986 (5623)
Seq/√Len:	279.0

ECOLI - ARLY ASPA FUMC PUR8
BACSU - ARLY PUR8 ASPA FUMC
HALSA - ARLY FUMC Q9HS42
SULSO - Q980P8 ARLY FUMC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
46_K	56_E	3.768	1.00
39_L	64_N	3.281	1.00
47_K	211_Y	3.233	1.00
43_A	60_R	3.210	1.00
355_V	358_Q	3.137	1.00
126_G	187_M	3.061	1.00
394_T	398_R	2.957	1.00
302_D	331_T	2.863	1.00
43_A	215_L	2.824	1.00
417_F	420_D	2.735	1.00
33_E	123_N	2.729	1.00
133_E	180_K	2.699	1.00
246_M	299_V	2.693	1.00
357_K	361_K	2.646	1.00
65_T	95_E	2.627	1.00
136_Q	177_E	2.625	1.00
138_A	343_T	2.602	1.00
138_A	347_Q	2.551	1.00
125_V	238_F	2.550	1.00
129_I	184_Q	2.545	1.00
295_K	338_S	2.492	1.00
29_N	333_K	2.463	1.00
165_F	351_V	2.431	1.00
189_R	237_E	2.411	1.00
211_Y	214_E	2.381	1.00
52_T	55_E	2.376	1.00
129_I	180_K	2.316	1.00
131_L	340_Q	2.314	1.00
142_K	145_A	2.286	1.00
122_K	191_N	2.250	1.00
243_S	303_M	2.239	1.00
46_K	53_A	2.206	1.00
134_A	343_T	2.200	1.00
394_T	409_E	2.153	1.00
191_N	219_D	2.129	1.00
148_E	353_K	2.118	1.00
270_D	350_T	2.111	1.00
343_T	347_Q	2.077	1.00
53_A	57_L	2.031	1.00
133_E	184_Q	2.027	1.00
298_R	327_G	1.960	1.00
141_E	347_Q	1.953	1.00
400_I	408_G	1.936	1.00
136_Q	180_K	1.926	1.00
131_L	336_E	1.889	1.00
355_V	359_A	1.874	1.00
185_D	189_R	1.854	1.00
210_D	214_E	1.847	1.00
357_K	428_Y	1.844	1.00
180_K	184_Q	1.843	1.00
211_Y	215_L	1.841	1.00
141_E	145_A	1.826	1.00
57_L	61_E	1.816	1.00
138_A	346_I	1.810	1.00
253_S	292_I	1.809	1.00
247_M	300_Y	1.806	1.00
403_S	422_Y	1.797	1.00
358_Q	362_Q	1.794	1.00
132_I	245_L	1.792	1.00
268_E	352_N	1.779	1.00
182_R	237_E	1.751	1.00
36_T	123_N	1.741	1.00
39_L	60_R	1.723	1.00
193_S	213_A	1.710	1.00
140_I	177_E	1.710	1.00
185_D	188_K	1.691	1.00
222_Y	228_G	1.679	1.00
146_N	149_T	1.679	1.00
418_E	422_Y	1.661	1.00
426_D	429_Y	1.657	1.00
249_L	292_I	1.655	1.00
179_D	248_H	1.629	1.00
56_E	60_R	1.588	1.00
136_Q	173_F	1.587	1.00
353_K	357_K	1.568	1.00
178_R	227_D	1.559	1.00
407_F	418_E	1.554	1.00
387_V	390_K	1.533	1.00
55_E	102_K	1.522	1.00
420_D	423_T	1.511	1.00
43_A	211_Y	1.509	1.00
236_L	310_M	1.508	1.00
253_S	342_F	1.504	1.00
131_L	343_T	1.484	1.00
400_I	405_M	1.476	1.00
243_S	307_F	1.469	1.00
292_I	342_F	1.467	1.00
238_F	332_V	1.454	1.00
121_L	328_M	1.452	1.00
298_R	330_D	1.451	1.00
97_G	100_G	1.441	1.00
305_G	323_E	1.429	1.00
143_A	173_F	1.417	1.00
197_C	228_G	1.410	1.00
35_I	88_I	1.408	1.00
142_K	146_N	1.406	1.00
44_M	211_Y	1.392	1.00
178_R	233_D	1.386	1.00
232_R	321_L	1.382	1.00
188_K	219_D	1.372	1.00
186_S	241_N	1.361	1.00
407_F	422_Y	1.356	1.00
401_Y	404_D	1.352	1.00
352_N	355_V	1.347	1.00
124_H	336_E	1.340	1.00
181_E	189_R	1.339	1.00
136_Q	176_L	1.331	1.00
289_A	345_M	1.328	1.00
268_E	350_T	1.324	1.00
258_L	314_P	1.321	1.00
32_A	36_T	1.319	1.00
91_M	95_E	1.298	1.00
354_D	358_Q	1.296	1.00
387_V	415_T	1.295	1.00
270_D	348_T	1.294	1.00
134_A	347_Q	1.291	1.00
39_L	67_L	1.285	1.00
39_L	43_A	1.280	1.00
106_G	208_D	1.276	1.00
129_I	187_M	1.269	1.00
169_L	172_Y	1.266	1.00
29_N	124_H	1.266	1.00
14_E	17_V	1.265	1.00
165_F	169_L	1.261	1.00
121_L	238_F	1.259	1.00
400_I	404_D	1.255	1.00
240_S	244_M	1.255	1.00
140_I	144_E	1.250	1.00
58_K	99_L	1.245	1.00
252_F	342_F	1.242	1.00
135_F	343_T	1.241	1.00
34_D	112_Q	1.240	1.00
394_T	405_M	1.237	1.00
236_L	244_M	1.232	1.00
239_L	306_L	1.231	1.00
50_I	105_T	1.215	1.00
58_K	61_E	1.214	1.00
127_H	336_E	1.213	1.00
88_I	92_L	1.208	1.00
172_Y	316_A	1.207	1.00
304_M	308_T	1.202	1.00
144_E	147_V	1.199	1.00
138_A	141_E	1.192	1.00
239_L	328_M	1.189	1.00
149_T	353_K	1.176	1.00
373_Y	424_V	1.175	1.00
292_I	338_S	1.174	1.00
69_K	95_E	1.170	1.00
301_G	305_G	1.166	1.00
132_I	176_L	1.152	1.00
306_L	328_M	1.147	1.00
245_L	339_L	1.146	1.00
300_Y	308_T	1.137	1.00
42_A	51_L	1.137	1.00
245_L	335_V	1.134	1.00
146_N	353_K	1.130	1.00
246_M	335_V	1.126	1.00
35_I	66_L	1.121	1.00
64_N	68_Q	1.118	1.00
165_F	356_M	1.118	1.00
213_A	219_D	1.117	1.00
24_I	330_D	1.116	1.00
135_F	176_L	1.114	1.00
398_R	405_M	1.110	1.00
373_Y	420_D	1.110	1.00
239_L	331_T	1.106	1.00
93_I	100_G	1.102	1.00
235_I	328_M	1.101	1.00
140_I	173_F	1.100	1.00
135_F	346_I	1.096	1.00
183_F	245_L	1.095	1.00
403_S	407_F	1.093	1.00
92_L	103_L	1.093	1.00
40_A	215_L	1.083	1.00
265_K	355_V	1.083	1.00
256_I	289_A	1.080	1.00
32_A	67_L	1.073	1.00
47_K	215_L	1.073	1.00
159_R	263_E	1.070	1.00
139_L	252_F	1.065	1.00
129_I	133_E	1.065	1.00
37_G	112_Q	1.064	1.00
131_L	134_A	1.063	1.00
147_V	166_A	1.062	1.00
170_L	224_N	1.062	1.00
134_A	340_Q	1.058	1.00
99_L	102_K	1.057	1.00
53_A	56_E	1.056	1.00
35_I	67_L	1.054	1.00
299_V	335_V	1.052	1.00
148_E	166_A	1.052	1.00
61_E	65_T	1.050	1.00
241_N	245_L	1.046	1.00
128_I	335_V	1.045	1.00
296_T	300_Y	1.042	1.00
151_L	356_M	1.041	1.00
57_L	60_R	1.038	1.00
250_S	293_R	1.038	1.00
133_E	137_S	1.037	1.00
298_R	326_E	1.036	1.00
117_M	325_K	1.033	1.00
91_M	94_D	1.028	1.00
162_P	360_T	1.021	1.00
172_Y	252_F	1.021	1.00
65_T	70_A	1.020	1.00
159_R	262_Q	1.018	1.00
142_K	169_L	1.016	1.00
370_L	406_P	1.016	1.00
69_K	91_M	1.013	1.00
60_R	64_N	1.012	1.00
124_H	127_H	1.007	1.00
238_F	328_M	1.006	1.00
32_A	123_N	1.004	1.00
81_Y	90_K	1.002	1.00
181_E	188_K	1.002	1.00
115_T	193_S	0.998	1.00
33_E	119_L	0.990	1.00
14_E	18_D	0.987	1.00
122_K	218_F	0.987	1.00
125_V	187_M	0.986	1.00
122_K	126_G	0.983	1.00
198_G	279_M	0.982	1.00
374_L	388_V	0.981	1.00
163_I	200_L	0.981	1.00
142_K	346_I	0.981	1.00
106_G	207_I	0.981	1.00
150_I	431_V	0.977	1.00
122_K	187_M	0.976	1.00
64_N	67_L	0.975	1.00
117_M	235_I	0.974	1.00
28_Q	32_A	0.971	1.00
67_L	70_A	0.971	1.00
147_V	164_S	0.965	1.00
149_T	356_M	0.965	1.00
185_D	237_E	0.964	1.00
98_P	101_G	0.961	1.00
46_K	57_L	0.961	1.00
305_G	327_G	0.960	1.00
164_S	431_V	0.959	1.00
132_I	180_K	0.959	1.00
117_M	328_M	0.957	1.00
273_Y	344_G	0.957	1.00
393_Y	397_E	0.950	1.00
32_A	71_E	0.950	1.00
58_K	62_G	0.950	1.00
50_I	208_D	0.944	1.00
174_W	178_R	0.939	1.00
125_V	183_F	0.939	1.00
181_E	185_D	0.938	1.00
36_T	215_L	0.937	1.00
187_M	191_N	0.929	1.00
298_R	334_T	0.928	1.00
156_H	290_E	0.926	1.00
249_L	342_F	0.918	1.00
62_G	65_T	0.917	1.00
394_T	397_E	0.916	1.00
73_G	94_D	0.913	1.00
124_H	332_V	0.913	1.00
34_D	37_G	0.912	1.00
193_S	212_S	0.909	1.00
256_I	349_M	0.909	1.00
153_G	163_I	0.908	1.00
240_S	303_M	0.908	1.00
247_M	310_M	0.908	1.00
37_G	115_T	0.907	1.00
395_C	405_M	0.907	1.00
249_L	339_L	0.903	1.00
326_E	330_D	0.903	1.00
302_D	330_D	0.902	1.00
44_M	48_C	0.895	1.00
390_K	409_E	0.893	1.00
136_Q	140_I	0.889	1.00
270_D	352_N	0.888	1.00
28_Q	72_E	0.888	1.00
62_G	96_I	0.888	1.00
269_L	349_M	0.887	1.00
239_L	303_M	0.886	1.00
145_A	350_T	0.885	1.00
54_E	57_L	0.884	1.00
29_N	123_N	0.882	1.00
68_Q	72_E	0.880	1.00
265_K	352_N	0.878	1.00
191_N	218_F	0.872	1.00
81_Y	87_N	0.872	1.00
154_Y	159_R	0.868	1.00
419_E	423_T	0.868	1.00
33_E	120_Y	0.865	1.00
212_S	216_L	0.864	1.00
163_I	226_L	0.862	1.00
72_E	76_E	0.862	1.00
242_S	335_V	0.861	1.00
48_C	208_D	0.858	1.00
139_L	169_L	0.857	1.00
404_D	408_G	0.857	1.00
68_Q	71_E	0.857	1.00
139_L	346_I	0.855	1.00
403_S	418_E	0.853	1.00
258_L	264_F	0.852	1.00
303_M	307_F	0.849	1.00
149_T	351_V	0.848	1.00
406_P	409_E	0.847	1.00
291_L	341_I	0.844	1.00
47_K	53_A	0.844	1.00
71_E	95_E	0.842	1.00
394_T	408_G	0.841	1.00
174_W	223_E	0.841	1.00
209_R	213_A	0.839	1.00
150_I	360_T	0.837	1.00
65_T	69_K	0.835	1.00
157_L	258_L	0.833	1.00
143_A	170_L	0.832	1.00
173_F	177_E	0.827	1.00
360_T	427_P	0.827	1.00
139_L	173_F	0.826	1.00
137_S	141_E	0.818	0.99
65_T	71_E	0.817	0.99
250_S	311_K	0.813	0.99
67_L	71_E	0.813	0.99
43_A	56_E	0.812	0.99
54_E	58_K	0.808	0.99
231_D	248_H	0.806	0.99
391_L	405_M	0.805	0.99
421_I	425_L	0.803	0.99
374_L	387_V	0.803	0.99
167_H	225_S	0.801	0.99
138_A	142_K	0.800	0.99
394_T	400_I	0.797	0.99
34_D	88_I	0.796	0.99
32_A	72_E	0.794	0.99
145_A	353_K	0.793	0.99
36_T	67_L	0.791	0.99
168_H	259_W	0.783	0.99
400_I	409_E	0.783	0.99
148_E	428_Y	0.782	0.99
297_G	305_G	0.779	0.99
209_R	212_S	0.776	0.99
36_T	212_S	0.774	0.99
361_K	403_S	0.774	0.99
188_K	191_N	0.770	0.99
42_A	56_E	0.770	0.99
41_H	107_R	0.768	0.99
178_R	192_K	0.767	0.99
176_L	339_L	0.763	0.99
157_L	261_S	0.763	0.99
146_N	351_V	0.762	0.99
47_K	208_D	0.761	0.99
237_E	240_S	0.761	0.99
209_R	221_I	0.759	0.99
194_P	228_G	0.758	0.99
309_I	323_E	0.757	0.99
135_F	339_L	0.753	0.99
391_L	402_L	0.751	0.99
192_K	234_F	0.751	0.99
46_K	51_L	0.749	0.99
212_S	215_L	0.745	0.99
58_K	96_I	0.741	0.99
69_K	74_A	0.739	0.99
43_A	47_K	0.739	0.99
247_M	307_F	0.738	0.99
420_D	424_V	0.735	0.99
298_R	302_D	0.734	0.99
300_Y	304_M	0.733	0.99
75_L	87_N	0.726	0.99
17_V	22_A	0.720	0.99
152_P	365_S	0.719	0.99
154_Y	263_E	0.718	0.99
391_L	406_P	0.718	0.99
386_E	390_K	0.717	0.99
151_L	168_H	0.717	0.99
230_S	316_A	0.715	0.99
300_Y	307_F	0.714	0.99
193_S	221_I	0.713	0.99
233_D	248_H	0.709	0.99
125_V	186_S	0.709	0.99
50_I	106_G	0.708	0.99
238_F	242_S	0.708	0.99
30_L	113_V	0.707	0.98
351_V	356_M	0.707	0.98
139_L	176_L	0.707	0.98
132_I	339_L	0.704	0.98
361_K	401_Y	0.702	0.98
369_E	430_A	0.701	0.98
17_V	288_M	0.700	0.98
192_K	222_Y	0.699	0.98
175_M	231_D	0.696	0.98
398_R	409_E	0.695	0.98
21_G	319_K	0.694	0.98
171_A	251_R	0.694	0.98
176_L	179_D	0.693	0.98
253_S	289_A	0.690	0.98
58_K	98_P	0.690	0.98
128_I	332_V	0.689	0.98
175_M	248_H	0.689	0.98
354_D	357_K	0.688	0.98
15_K	19_E	0.687	0.98
227_D	233_D	0.684	0.98
226_L	316_A	0.683	0.98
235_I	306_L	0.683	0.98
51_L	105_T	0.682	0.98
195_L	212_S	0.682	0.98
90_K	94_D	0.682	0.98
390_K	394_T	0.681	0.98
40_A	43_A	0.680	0.98
48_C	211_Y	0.678	0.98
339_L	343_T	0.676	0.98
236_L	306_L	0.676	0.98
262_Q	265_K	0.675	0.98
39_L	56_E	0.674	0.98
118_H	234_F	0.673	0.98
182_R	233_D	0.672	0.98
304_M	307_F	0.672	0.98
55_E	99_L	0.671	0.98
24_I	326_E	0.671	0.98
428_Y	432_E	0.669	0.98
159_R	363_D	0.667	0.98
69_K	72_E	0.666	0.98
137_S	140_I	0.666	0.98
299_V	331_T	0.665	0.98
267_I	349_M	0.664	0.98
42_A	59_I	0.662	0.98
405_M	409_E	0.662	0.98
341_I	344_G	0.661	0.98
141_E	144_E	0.659	0.98
254_E	293_R	0.658	0.98
133_E	136_Q	0.657	0.98
127_H	131_L	0.656	0.98
149_T	164_S	0.654	0.97
370_L	421_I	0.653	0.97
133_E	177_E	0.652	0.97
146_N	165_F	0.650	0.97
134_A	138_A	0.649	0.97
179_D	244_M	0.648	0.97
144_E	148_E	0.647	0.97
169_L	356_M	0.647	0.97
149_T	357_K	0.647	0.97
191_N	213_A	0.647	0.97
66_L	70_A	0.645	0.97
122_K	219_D	0.644	0.97
345_M	349_M	0.643	0.97
96_I	103_L	0.641	0.97
227_D	248_H	0.640	0.97
221_I	225_S	0.640	0.97
186_S	190_I	0.638	0.97
152_P	360_T	0.638	0.97
297_G	308_T	0.637	0.97
266_F	359_A	0.637	0.97
59_I	92_L	0.636	0.97
25_S	124_H	0.636	0.97
259_W	315_L	0.635	0.97
26_F	326_E	0.634	0.97
151_L	163_I	0.634	0.97
188_K	192_K	0.632	0.97
63_L	66_L	0.632	0.97
295_K	334_T	0.631	0.97
143_A	147_V	0.631	0.97
42_A	60_R	0.630	0.97
261_S	264_F	0.627	0.97
121_L	332_V	0.624	0.97
297_G	309_I	0.624	0.97
39_L	63_L	0.623	0.97
256_I	342_F	0.621	0.97
181_E	184_Q	0.621	0.97
128_I	242_S	0.621	0.97
181_E	192_K	0.618	0.96
182_R	189_R	0.617	0.96
120_Y	332_V	0.616	0.96
416_L	424_V	0.616	0.96
46_K	60_R	0.616	0.96
182_R	185_D	0.615	0.96
236_L	307_F	0.615	0.96
120_Y	329_F	0.612	0.96
213_A	216_L	0.612	0.96
131_L	339_L	0.610	0.96
126_G	184_Q	0.610	0.96
423_T	429_Y	0.608	0.96
39_L	215_L	0.605	0.96
252_F	346_I	0.604	0.96
63_L	92_L	0.602	0.96
70_A	73_G	0.601	0.96
273_Y	348_T	0.600	0.96
179_D	182_R	0.600	0.96
125_V	129_I	0.600	0.96
360_T	365_S	0.598	0.96
176_L	249_L	0.594	0.96
243_S	247_M	0.594	0.96
328_M	332_V	0.593	0.96
236_L	240_S	0.592	0.96
405_M	408_G	0.591	0.95
423_T	426_D	0.591	0.95
164_S	432_E	0.591	0.95
359_A	362_Q	0.590	0.95
172_Y	175_M	0.590	0.95
42_A	103_L	0.590	0.95
69_K	73_G	0.590	0.95
388_V	392_V	0.589	0.95
125_V	190_I	0.589	0.95
59_I	96_I	0.587	0.95
96_I	99_L	0.586	0.95
142_K	349_M	0.585	0.95
366_N	430_A	0.584	0.95
288_M	345_M	0.583	0.95
327_G	330_D	0.582	0.95
140_I	143_A	0.582	0.95
22_A	25_S	0.580	0.95
126_G	191_N	0.577	0.95
400_I	406_P	0.574	0.95
154_Y	264_F	0.572	0.95
71_E	74_A	0.572	0.95
330_D	334_T	0.571	0.95
174_W	177_E	0.571	0.95
250_S	308_T	0.570	0.95
126_G	218_F	0.570	0.95
253_S	293_R	0.568	0.94
293_R	320_D	0.568	0.94
292_I	345_M	0.568	0.94
37_G	116_D	0.568	0.94
416_L	420_D	0.567	0.94
81_Y	86_L	0.566	0.94
55_E	58_K	0.565	0.94
130_E	134_A	0.565	0.94
175_M	230_S	0.565	0.94
132_I	183_F	0.564	0.94
299_V	334_T	0.563	0.94
150_I	427_P	0.562	0.94
362_Q	401_Y	0.561	0.94
95_E	99_L	0.561	0.94
353_K	356_M	0.561	0.94
31_V	70_A	0.560	0.94
88_I	116_D	0.560	0.94
186_S	238_F	0.559	0.94
36_T	40_A	0.558	0.94
396_I	399_G	0.558	0.94
168_H	255_E	0.557	0.94
301_G	304_M	0.557	0.94
129_I	241_N	0.555	0.94
129_I	132_I	0.555	0.94
174_W	224_N	0.554	0.94
51_L	55_E	0.554	0.94
21_G	291_L	0.554	0.94
169_L	349_M	0.553	0.94
297_G	311_K	0.552	0.94
20_F	338_S	0.552	0.94
20_F	292_I	0.550	0.93
364_F	402_L	0.550	0.93
66_L	69_K	0.548	0.93
109_R	194_P	0.548	0.93
414_S	417_F	0.547	0.93
24_I	29_N	0.545	0.93
176_L	245_L	0.545	0.93
364_F	395_C	0.545	0.93
177_E	181_E	0.544	0.93
429_Y	432_E	0.544	0.93
308_T	312_G	0.543	0.93
156_H	319_K	0.543	0.93
75_L	91_M	0.542	0.93
404_D	418_E	0.541	0.93
33_E	36_T	0.541	0.93
37_G	195_L	0.541	0.93
213_A	218_F	0.540	0.93
183_F	241_N	0.538	0.93
163_I	167_H	0.536	0.93
168_H	316_A	0.535	0.92
52_T	56_E	0.535	0.92
15_K	18_D	0.533	0.92
36_T	216_L	0.532	0.92
240_S	243_S	0.531	0.92
310_M	321_L	0.531	0.92
151_L	259_W	0.531	0.92
59_I	99_L	0.530	0.92
29_N	127_H	0.530	0.92
123_N	126_G	0.529	0.92
390_K	397_E	0.528	0.92
258_L	261_S	0.527	0.92
182_R	244_M	0.527	0.92
178_R	237_E	0.525	0.92
258_L	315_L	0.524	0.92
41_H	212_S	0.524	0.92
292_I	296_T	0.524	0.92
366_N	425_L	0.523	0.92
274_A	287_D	0.522	0.92
195_L	221_I	0.522	0.92
210_D	213_A	0.522	0.92
237_E	244_M	0.521	0.91
152_P	359_A	0.520	0.91
186_S	237_E	0.519	0.91
367_A	388_V	0.519	0.91
391_L	409_E	0.518	0.91
242_S	245_L	0.517	0.91
66_L	72_E	0.517	0.91
146_N	166_A	0.514	0.91
395_C	400_I	0.512	0.91
19_E	337_G	0.512	0.91
179_D	241_N	0.511	0.91
121_L	190_I	0.511	0.91
244_M	248_H	0.511	0.91
178_R	189_R	0.510	0.91
240_S	307_F	0.507	0.90
94_D	97_G	0.507	0.90
271_D	284_K	0.506	0.90
260_C	269_L	0.506	0.90
77_F	84_I	0.506	0.90
233_D	237_E	0.506	0.90
135_F	138_A	0.505	0.90
194_P	229_V	0.504	0.90
387_V	416_L	0.503	0.90
184_Q	188_K	0.502	0.90
149_T	165_F	0.501	0.90
419_E	422_Y	0.501	0.90
51_L	56_E	0.500	0.90

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2e9fA	4	0.9718	100	0.122	Contact Map
1tj7A	4	0.9848	100	0.132	Contact Map
1k7wA	4	0.974	100	0.136	Contact Map
1q5nA	4	0.9024	100	0.212	Contact Map
1re5A	4	0.9414	100	0.212	Contact Map
1c3cA	4	0.9046	100	0.23	Contact Map
3c8tA	4	0.9046	100	0.237	Contact Map
2pfmA	4	0.9197	100	0.244	Contact Map
4eeiA	4	0.8959	100	0.252	Contact Map
3r6qA	4	0.9154	100	0.257	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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