YERD - BACSU - GREMLIN Contacts

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YERD - Glutamate synthase large subunit-like protein YerD

UniProt:	O34849	Sequences: METIIIALIAFIIGIIAIPIVLFAWIYIKDEKQQEHSILRNYPVIGRFRYILEKIGPELRQYLYSNDNEEQPFSRKEYEQTVISGKYKSRMMGFGSVRDFDKPGYYIRNAMFPKQREEMHVNQTPKIETQIYKMDADNLFKRKEHAEHIKADPYFLHPDDVQVIGEHTCEKPFYVKGLVGQSAMSYGSLGERAVTALSKGLHLAGGTWMNTGEGGLSEYHLKGGADIICQIGPGLFGVRKRNGEFSWEEFKRKSRIDQIKAFELKLAQGAKTRGGHVDGAKVSEEVADIRNVEPGKSIDSPNRFYEFSNPPEMLDFIEKLRDVGQKPVGIKLVAGHPEELHELFSHMQKSGKHPDFITIDGSEGGTGASFYELADTVGLPIMTALPIVDTLLKQYGLRSQLKIFASGKLLTPDKIAVALALGADFVNIARGMMFSVGCIRALVCHTNTCPAGVATTDPKLQKALSVEEKQHRVCNYVISLREGLFNLAAAAGINSPIHFSKEHVVYRKEDGSIINIDNLIHQFVS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	525 (438)
Sequences:	1981 (695)
Seq/√Len:	33.2

ECOLI - GLTB
BACSU - YERD GLTA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
416_A	484_L	5.454	1.00
495_S	498_H	5.250	1.00
493_I	499_F	4.778	1.00
357_I	401_L	4.594	1.00
138_N	476_Y	4.247	1.00
488_A	499_F	4.102	1.00
225_A	260_K	3.842	1.00
135_D	139_L	3.695	1.00
156_L	506_Y	3.618	1.00
227_I	260_K	3.600	1.00
172_P	482_E	3.577	1.00
357_I	403_I	3.359	1.00
127_I	435_S	3.335	1.00
100_F	104_G	3.311	1.00
168_T	494_N	3.265	1.00
176_K	204_A	3.182	1.00
72_P	75_R	3.125	1.00
405_A	418_A	3.054	1.00
101_D	104_G	2.980	1.00
240_K	323_V	2.973	1.00
197_L	473_V	2.949	1.00
494_N	498_H	2.945	1.00
136_A	486_N	2.890	1.00
447_N	457_D	2.889	1.00
459_K	462_K	2.872	1.00
98_R	104_G	2.871	1.00
348_Q	357_I	2.868	1.00
62_Y	73_F	2.852	1.00
99_D	103_P	2.804	1.00
132_Y	136_A	2.782	1.00
196_A	436_V	2.757	1.00
493_I	504_V	2.635	1.00
340_L	359_I	2.611	1.00
416_A	487_L	2.600	1.00
199_K	203_L	2.573	1.00
488_A	496_P	2.563	1.00
132_Y	486_N	2.528	1.00
98_R	102_K	2.507	1.00
186_Y	285_E	2.505	1.00
348_Q	401_L	2.504	1.00
499_F	504_V	2.501	1.00
98_R	103_P	2.446	1.00
204_A	474_C	2.431	0.99
441_A	450_P	2.411	0.99
231_I	262_F	2.402	0.99
186_Y	289_I	2.397	0.99
102_K	105_Y	2.397	0.99
122_N	137_D	2.374	0.99
158_P	506_Y	2.345	0.99
195_T	224_G	2.325	0.99
420_A	499_F	2.274	0.99
98_R	105_Y	2.254	0.99
101_D	105_Y	2.236	0.99
98_R	101_D	2.182	0.99
139_L	483_G	2.128	0.99
191_E	195_T	2.110	0.99
160_D	164_I	2.096	0.98
116_R	119_M	2.089	0.98
488_A	495_S	2.088	0.98
99_D	105_Y	2.009	0.98
203_L	474_C	1.943	0.97
171_K	174_Y	1.934	0.97
340_L	388_V	1.891	0.97
484_L	488_A	1.888	0.97
487_L	490_A	1.885	0.97
405_A	409_L	1.861	0.97
99_D	104_G	1.858	0.97
173_F	478_I	1.852	0.97
415_I	480_L	1.849	0.97
156_L	508_K	1.832	0.96
496_P	499_F	1.803	0.96
172_P	478_I	1.800	0.96
161_V	493_I	1.790	0.96
180_G	404_F	1.782	0.96
469_K	472_R	1.763	0.95
173_F	176_K	1.752	0.95
157_H	491_A	1.752	0.95
100_F	103_P	1.746	0.95
135_D	476_Y	1.743	0.95
261_A	327_P	1.724	0.95
99_D	102_K	1.717	0.95
329_G	356_F	1.688	0.94
416_A	499_F	1.684	0.94
176_K	478_I	1.682	0.94
78_Y	82_V	1.670	0.94
262_F	328_V	1.656	0.94
77_E	81_T	1.656	0.94
100_F	105_Y	1.647	0.93
159_D	506_Y	1.632	0.93
484_L	496_P	1.630	0.93
71_Q	75_R	1.614	0.93
334_A	379_L	1.601	0.92
263_E	404_F	1.596	0.92
488_A	493_I	1.582	0.92
388_V	403_I	1.571	0.92
413_D	417_V	1.568	0.92
182_S	429_A	1.548	0.91
420_A	493_I	1.546	0.91
183_A	210_N	1.530	0.91
191_E	285_E	1.527	0.90
186_Y	191_E	1.516	0.90
199_K	470_Q	1.513	0.90
218_E	254_S	1.495	0.90
501_K	504_V	1.494	0.89
416_A	496_P	1.488	0.89
254_S	258_Q	1.481	0.89
327_P	402_K	1.473	0.89
476_Y	480_L	1.464	0.89
471_H	474_C	1.463	0.88
197_L	432_M	1.460	0.88
84_S	88_K	1.448	0.88
159_D	163_V	1.435	0.87
79_E	515_N	1.430	0.87
58_E	76_K	1.416	0.87
192_R	461_Q	1.414	0.87
358_T	427_N	1.410	0.87
128_E	472_R	1.408	0.86
161_V	504_V	1.402	0.86
188_S	454_A	1.381	0.85
285_E	289_I	1.380	0.85
483_G	486_N	1.380	0.85
132_Y	482_E	1.378	0.85
174_Y	177_G	1.369	0.85
145_H	150_K	1.366	0.85
79_E	514_I	1.365	0.85
279_G	295_G	1.357	0.84
139_L	480_L	1.354	0.84
137_D	140_F	1.346	0.84
225_A	258_Q	1.336	0.83
159_D	490_A	1.332	0.83
391_L	394_Q	1.314	0.82
495_S	499_F	1.312	0.82
112_F	149_I	1.311	0.82
160_D	163_V	1.306	0.82
510_D	513_I	1.281	0.81
261_A	329_G	1.280	0.81
58_E	62_Y	1.277	0.80
164_I	494_N	1.271	0.80
284_E	288_D	1.267	0.80
188_S	429_A	1.263	0.80
221_L	254_S	1.227	0.78
263_E	329_G	1.225	0.78
130_Q	475_N	1.218	0.77
159_D	162_Q	1.213	0.77
181_Q	197_L	1.212	0.77
358_T	424_D	1.208	0.77
283_S	447_N	1.198	0.76
186_Y	443_V	1.195	0.76
359_I	388_V	1.187	0.75
60_R	63_L	1.167	0.74
257_D	323_V	1.167	0.74
482_E	486_N	1.165	0.74
345_S	391_L	1.159	0.74
340_L	405_A	1.155	0.73
183_A	188_S	1.141	0.72
327_P	356_F	1.135	0.72
186_Y	286_V	1.132	0.72
219_Y	288_D	1.132	0.72
189_L	454_A	1.129	0.72
139_L	143_K	1.116	0.71
284_E	443_V	1.114	0.71
420_A	502_E	1.103	0.70
160_D	493_I	1.095	0.69
140_F	144_E	1.095	0.69
156_L	159_D	1.093	0.69
79_E	83_I	1.093	0.69
419_L	496_P	1.093	0.69
409_L	426_V	1.093	0.69
155_F	507_R	1.082	0.68
150_K	153_P	1.075	0.68
412_P	483_G	1.073	0.68
336_H	383_T	1.069	0.67
418_A	426_V	1.066	0.67
404_F	477_V	1.063	0.67
221_L	258_Q	1.053	0.66
183_A	263_E	1.045	0.66
58_E	72_P	1.038	0.65
404_F	408_K	1.035	0.65
288_D	291_N	1.035	0.65
168_T	498_H	1.028	0.64
145_H	434_F	1.023	0.64
309_N	312_E	1.022	0.64
142_R	145_H	1.021	0.64
165_G	168_T	1.020	0.64
65_S	336_H	1.015	0.63
285_E	288_D	1.015	0.63
67_D	383_T	1.014	0.63
506_Y	510_D	1.014	0.63
114_K	150_K	1.012	0.63
431_G	476_Y	1.002	0.62
203_L	470_Q	1.000	0.62
474_C	478_I	0.996	0.62
58_E	73_F	0.994	0.62
386_P	421_L	0.994	0.62
73_F	76_K	0.988	0.61
419_L	426_V	0.985	0.61
327_P	358_T	0.980	0.60
181_Q	432_M	0.969	0.60
396_G	399_S	0.968	0.59
221_L	369_S	0.964	0.59
210_N	263_E	0.959	0.59
112_F	116_R	0.955	0.58
389_D	393_K	0.954	0.58
436_V	473_V	0.949	0.58
207_T	227_I	0.939	0.57
139_L	411_T	0.932	0.57
157_H	416_A	0.929	0.56
432_M	478_I	0.927	0.56
206_G	260_K	0.923	0.56
286_V	447_N	0.923	0.56
159_D	493_I	0.921	0.56
335_G	388_V	0.917	0.55
176_K	206_G	0.915	0.55
280_A	284_E	0.907	0.55
161_V	490_A	0.906	0.54
371_Y	408_K	0.903	0.54
458_P	462_K	0.902	0.54
439_I	451_A	0.901	0.54
409_L	415_I	0.899	0.54
115_Q	443_V	0.899	0.54
218_E	291_N	0.899	0.54
262_F	326_K	0.899	0.54
318_E	322_D	0.897	0.54
404_F	410_L	0.895	0.54
116_R	141_K	0.892	0.53
157_H	487_L	0.888	0.53
262_F	288_D	0.886	0.53
145_H	153_P	0.884	0.53
122_N	134_M	0.882	0.52
484_L	487_L	0.879	0.52
127_I	477_V	0.878	0.52
211_T	260_K	0.876	0.52
159_D	164_I	0.871	0.52
280_A	371_Y	0.864	0.51
161_V	501_K	0.858	0.50
276_H	369_S	0.858	0.50
148_H	153_P	0.857	0.50
222_K	254_S	0.855	0.50
415_I	419_L	0.853	0.50
381_I	418_A	0.850	0.50
68_N	357_I	0.850	0.50
186_Y	405_A	0.847	0.50
432_M	473_V	0.846	0.49
293_E	296_K	0.844	0.49
283_S	443_V	0.842	0.49
136_A	140_F	0.841	0.49
59_L	66_N	0.839	0.49
284_E	294_P	0.835	0.48
484_L	499_F	0.828	0.48
334_A	359_I	0.827	0.48
115_Q	285_E	0.826	0.48
402_K	497_I	0.825	0.48
60_R	64_Y	0.824	0.48
164_I	489_A	0.823	0.47
408_K	429_A	0.823	0.47
436_V	453_V	0.821	0.47
96_S	100_F	0.817	0.47
416_A	419_L	0.817	0.47
193_A	436_V	0.816	0.47
188_S	433_M	0.815	0.47
150_K	363_E	0.812	0.47
90_R	140_F	0.812	0.47
172_P	176_K	0.811	0.46
385_L	405_A	0.810	0.46
153_P	458_P	0.809	0.46
78_Y	85_G	0.808	0.46
125_P	129_T	0.806	0.46
435_S	477_V	0.803	0.46
143_K	153_P	0.799	0.46
199_K	224_G	0.797	0.45
415_I	484_L	0.797	0.45
115_Q	434_F	0.796	0.45
165_G	494_N	0.796	0.45
112_F	147_E	0.796	0.45
335_G	343_L	0.792	0.45
131_I	134_M	0.790	0.45
270_A	277_V	0.785	0.44
263_E	356_F	0.770	0.43
404_F	441_A	0.768	0.43
431_G	478_I	0.768	0.43
196_A	453_V	0.767	0.43
62_Y	276_H	0.766	0.43
180_G	477_V	0.760	0.42
289_I	353_H	0.760	0.42
127_I	472_R	0.759	0.42
97_V	100_F	0.759	0.42
435_S	476_Y	0.758	0.42
126_K	479_S	0.755	0.42
114_K	434_F	0.754	0.42
371_Y	477_V	0.754	0.42
410_L	477_V	0.751	0.42
227_I	424_D	0.751	0.42
231_I	320_L	0.750	0.41
134_M	137_D	0.749	0.41
206_G	506_Y	0.749	0.41
261_A	358_T	0.746	0.41
362_S	453_V	0.732	0.40
285_E	447_N	0.726	0.40
231_I	328_V	0.721	0.39
84_S	197_L	0.721	0.39
61_Q	73_F	0.720	0.39
122_N	497_I	0.716	0.39
254_S	257_D	0.714	0.39
307_F	313_M	0.713	0.39
194_V	220_H	0.713	0.39
61_Q	64_Y	0.707	0.38
348_Q	403_I	0.705	0.38
119_M	142_R	0.703	0.38
490_A	493_I	0.703	0.38
137_D	141_K	0.701	0.38
418_A	496_P	0.699	0.37
425_F	450_P	0.699	0.37
181_Q	441_A	0.699	0.37
270_A	369_S	0.698	0.37
478_I	482_E	0.698	0.37
496_P	504_V	0.697	0.37
86_K	99_D	0.696	0.37
103_P	375_D	0.695	0.37
443_V	448_T	0.694	0.37
220_H	226_D	0.694	0.37
67_D	379_L	0.693	0.37
106_Y	254_S	0.689	0.37
197_L	228_I	0.689	0.37
120_H	405_A	0.688	0.37
79_E	376_T	0.688	0.37
297_S	318_E	0.687	0.36
434_F	440_R	0.687	0.36
186_Y	284_E	0.686	0.36
435_S	469_K	0.685	0.36
79_E	369_S	0.683	0.36
375_D	476_Y	0.682	0.36
189_L	193_A	0.682	0.36
182_S	206_G	0.680	0.36
132_Y	479_S	0.678	0.36
435_S	472_R	0.678	0.36
190_G	456_T	0.677	0.36
64_Y	211_T	0.677	0.36
196_A	469_K	0.677	0.36
371_Y	410_L	0.677	0.36
133_K	137_D	0.676	0.36
297_S	323_V	0.675	0.36
127_I	479_S	0.673	0.35
107_I	110_A	0.673	0.35
58_E	63_L	0.673	0.35
114_K	144_E	0.673	0.35
115_Q	431_G	0.672	0.35
175_V	399_S	0.672	0.35
80_Q	262_F	0.671	0.35
135_D	143_K	0.671	0.35
405_A	426_V	0.670	0.35
114_K	369_S	0.670	0.35
176_K	263_E	0.669	0.35
204_A	478_I	0.668	0.35
264_L	313_M	0.668	0.35
162_Q	166_E	0.665	0.35
71_Q	76_K	0.663	0.35
318_E	424_D	0.663	0.35
217_S	285_E	0.663	0.35
128_E	288_D	0.661	0.34
179_V	428_I	0.661	0.34
412_P	480_L	0.661	0.34
453_V	465_S	0.661	0.34
186_Y	283_S	0.660	0.34
207_T	356_F	0.659	0.34
363_E	381_I	0.659	0.34
403_I	510_D	0.659	0.34
157_H	413_D	0.659	0.34
77_E	80_Q	0.656	0.34
375_D	463_A	0.656	0.34
130_Q	134_M	0.654	0.34
311_P	346_H	0.653	0.34
180_G	261_A	0.652	0.34
74_S	78_Y	0.650	0.34
431_G	480_L	0.650	0.34
493_I	501_K	0.648	0.34
263_E	441_A	0.646	0.33
97_V	104_G	0.644	0.33
507_R	510_D	0.643	0.33
224_G	263_E	0.643	0.33
305_Y	308_S	0.641	0.33
115_Q	457_D	0.638	0.33
186_Y	328_V	0.638	0.33
207_T	425_F	0.637	0.33
163_V	490_A	0.637	0.33
258_Q	322_D	0.637	0.33
356_F	402_K	0.636	0.33
97_V	102_K	0.636	0.33
182_S	329_G	0.635	0.33
411_T	445_H	0.634	0.32
149_I	153_P	0.633	0.32
186_Y	293_E	0.631	0.32
428_I	432_M	0.628	0.32
186_Y	362_S	0.627	0.32
59_L	63_L	0.627	0.32
130_Q	478_I	0.625	0.32
89_S	94_F	0.625	0.32
61_Q	416_A	0.624	0.32
211_T	418_A	0.624	0.32
309_N	330_I	0.623	0.32
349_K	397_L	0.623	0.32
146_A	153_P	0.623	0.32
240_K	254_S	0.622	0.32
164_I	169_C	0.621	0.32
235_L	306_E	0.620	0.31
285_E	429_A	0.620	0.31
127_I	135_D	0.619	0.31
283_S	288_D	0.618	0.31
114_K	153_P	0.617	0.31
156_L	160_D	0.617	0.31
181_Q	477_V	0.617	0.31
276_H	393_K	0.616	0.31
74_S	81_T	0.615	0.31
439_I	463_A	0.615	0.31
278_D	369_S	0.614	0.31
206_G	480_L	0.613	0.31
136_A	139_L	0.612	0.31
420_A	504_V	0.612	0.31
68_N	151_A	0.612	0.31
82_V	85_G	0.610	0.31
178_L	267_A	0.609	0.31
153_P	188_S	0.609	0.31
369_S	377_V	0.608	0.31
234_G	451_A	0.608	0.31
390_T	394_Q	0.607	0.31
488_A	504_V	0.607	0.31
136_A	158_P	0.606	0.30
425_F	439_I	0.605	0.30
197_L	431_G	0.605	0.30
436_V	469_K	0.605	0.30
266_L	356_F	0.604	0.30
416_A	504_V	0.603	0.30
219_Y	222_K	0.603	0.30
85_G	89_S	0.603	0.30
261_A	436_V	0.601	0.30
182_S	472_R	0.600	0.30
207_T	389_D	0.600	0.30
182_S	322_D	0.600	0.30
115_Q	408_K	0.599	0.30
155_F	476_Y	0.599	0.30
327_P	427_N	0.598	0.30
59_L	205_G	0.598	0.30
61_Q	165_G	0.598	0.30
183_A	206_G	0.597	0.30
180_G	284_E	0.596	0.30
228_I	357_I	0.595	0.30
327_P	353_H	0.595	0.30
432_M	477_V	0.594	0.30
72_P	490_A	0.594	0.30
129_T	134_M	0.593	0.30
155_F	506_Y	0.592	0.29
82_V	334_A	0.591	0.29
191_E	224_G	0.591	0.29
228_I	446_T	0.591	0.29
114_K	363_E	0.590	0.29
342_E	345_S	0.590	0.29
182_S	441_A	0.590	0.29
308_S	346_H	0.588	0.29
280_A	288_D	0.588	0.29
173_F	177_G	0.586	0.29
457_D	465_S	0.586	0.29
420_A	491_A	0.586	0.29
330_I	346_H	0.585	0.29
370_F	373_L	0.584	0.29
276_H	373_L	0.584	0.29
108_R	389_D	0.583	0.29
182_S	191_E	0.583	0.29
284_E	447_N	0.583	0.29
293_E	297_S	0.581	0.29
343_L	376_T	0.581	0.29
156_L	509_E	0.581	0.29
67_D	155_F	0.581	0.29
491_A	499_F	0.581	0.29
181_Q	184_M	0.580	0.29
126_K	427_N	0.580	0.29
254_S	424_D	0.579	0.29
191_E	283_S	0.579	0.29
456_T	461_Q	0.579	0.29
125_P	134_M	0.579	0.29
408_K	435_S	0.578	0.29
426_V	496_P	0.578	0.29
80_Q	362_S	0.578	0.29
122_N	141_K	0.578	0.29
180_G	443_V	0.576	0.28
296_K	389_D	0.576	0.28
263_E	358_T	0.575	0.28
309_N	349_K	0.574	0.28
292_V	296_K	0.574	0.28
94_F	99_D	0.574	0.28
303_R	308_S	0.574	0.28
415_I	432_M	0.572	0.28
363_E	443_V	0.571	0.28
261_A	379_L	0.571	0.28
436_V	474_C	0.566	0.28
120_H	436_V	0.566	0.28
74_S	85_G	0.566	0.28
389_D	453_V	0.565	0.28
234_G	495_S	0.565	0.28
356_F	404_F	0.565	0.28
107_I	439_I	0.565	0.28
169_C	489_A	0.565	0.28
374_A	389_D	0.564	0.28
176_K	183_A	0.564	0.28
156_L	490_A	0.564	0.28
260_K	356_F	0.563	0.28
508_K	511_G	0.563	0.28
453_V	484_L	0.563	0.28
189_L	327_P	0.562	0.27
138_N	390_T	0.562	0.27
74_S	487_L	0.561	0.27
172_P	486_N	0.560	0.27
224_G	328_V	0.559	0.27
270_A	363_E	0.559	0.27
104_G	375_D	0.559	0.27
180_G	206_G	0.558	0.27
473_V	477_V	0.558	0.27
283_S	457_D	0.558	0.27
321_R	353_H	0.558	0.27
415_I	426_V	0.558	0.27
340_L	418_A	0.558	0.27
448_T	457_D	0.557	0.27
508_K	512_S	0.557	0.27
420_A	488_A	0.555	0.27
71_Q	79_E	0.555	0.27
112_F	409_L	0.554	0.27
385_L	399_S	0.554	0.27
95_G	167_H	0.553	0.27
416_A	488_A	0.553	0.27
234_G	454_A	0.553	0.27
61_Q	356_F	0.553	0.27
95_G	100_F	0.552	0.27
114_K	410_L	0.552	0.27
315_D	371_Y	0.551	0.27
276_H	297_S	0.551	0.27
164_I	498_H	0.550	0.27
78_Y	328_V	0.549	0.27
191_E	217_S	0.547	0.26
210_N	329_G	0.547	0.26
431_G	473_V	0.546	0.26
238_V	307_F	0.546	0.26
196_A	471_H	0.544	0.26
155_F	350_S	0.544	0.26
71_Q	318_E	0.543	0.26
186_Y	497_I	0.543	0.26
180_G	408_K	0.543	0.26
68_N	276_H	0.542	0.26
225_A	399_S	0.542	0.26
443_V	457_D	0.542	0.26
484_L	504_V	0.541	0.26
109_N	222_K	0.541	0.26
330_I	354_P	0.541	0.26
67_D	380_P	0.540	0.26
266_L	383_T	0.540	0.26
375_D	445_H	0.539	0.26
77_E	393_K	0.539	0.26
305_Y	310_P	0.538	0.26
280_A	283_S	0.538	0.26
191_E	289_I	0.538	0.26
69_E	86_K	0.537	0.26
485_F	489_A	0.536	0.26
315_D	319_K	0.536	0.26
152_D	308_S	0.535	0.26
74_S	399_S	0.535	0.26
129_T	137_D	0.533	0.26
261_A	285_E	0.533	0.26
130_Q	472_R	0.533	0.26
239_R	291_N	0.533	0.26
122_N	127_I	0.532	0.25
308_S	311_P	0.531	0.25
174_Y	498_H	0.529	0.25
74_S	162_Q	0.529	0.25
329_G	389_D	0.528	0.25
311_P	349_K	0.528	0.25
157_H	403_I	0.528	0.25
87_Y	99_D	0.528	0.25
207_T	228_I	0.527	0.25
357_I	510_D	0.526	0.25
427_N	503_H	0.526	0.25
150_K	362_S	0.526	0.25
341_H	395_Y	0.526	0.25
282_V	314_L	0.526	0.25
266_L	270_A	0.525	0.25
188_S	374_A	0.525	0.25
441_A	446_T	0.525	0.25
180_G	283_S	0.525	0.25
240_K	297_S	0.524	0.25
65_S	78_Y	0.524	0.25
180_G	329_G	0.522	0.25
211_T	297_S	0.521	0.25
180_G	410_L	0.521	0.25
58_E	118_E	0.520	0.25
257_D	391_L	0.520	0.25
117_E	210_N	0.520	0.25
293_E	433_M	0.519	0.25
303_R	316_F	0.518	0.25
285_E	408_K	0.518	0.25
219_Y	289_I	0.518	0.25
135_D	138_N	0.517	0.25
276_H	370_F	0.517	0.25
117_E	123_Q	0.517	0.25
293_E	327_P	0.516	0.24
297_S	400_Q	0.516	0.24
159_D	504_V	0.516	0.24
62_Y	132_Y	0.516	0.24
309_N	346_H	0.515	0.24
313_M	330_I	0.515	0.24
310_P	346_H	0.515	0.24
404_F	432_M	0.515	0.24
171_K	396_G	0.514	0.24
211_T	286_V	0.514	0.24
142_R	149_I	0.514	0.24
107_I	448_T	0.513	0.24
235_L	346_H	0.513	0.24
80_Q	85_G	0.513	0.24
211_T	258_Q	0.513	0.24
323_V	340_L	0.512	0.24
161_V	167_H	0.512	0.24
118_E	122_N	0.512	0.24
61_Q	453_V	0.512	0.24
80_Q	369_S	0.511	0.24
404_F	443_V	0.510	0.24
132_Y	284_E	0.510	0.24
210_N	363_E	0.510	0.24
83_I	86_K	0.509	0.24
114_K	231_I	0.509	0.24
500_S	505_V	0.509	0.24
336_H	486_N	0.508	0.24
458_P	503_H	0.508	0.24
85_G	90_R	0.507	0.24
180_G	207_T	0.507	0.24
303_R	311_P	0.506	0.24
198_S	363_E	0.506	0.24
127_I	470_Q	0.506	0.24
408_K	469_K	0.505	0.24
236_F	365_G	0.505	0.24
197_L	297_S	0.505	0.24
82_V	508_K	0.505	0.24
295_G	320_L	0.504	0.24
425_F	441_A	0.504	0.24
206_G	510_D	0.504	0.24
106_Y	116_R	0.504	0.24
391_L	450_P	0.504	0.24
161_V	171_K	0.503	0.24
206_G	458_P	0.503	0.24
150_K	399_S	0.503	0.24
75_R	510_D	0.503	0.24
359_I	402_K	0.503	0.24
396_G	509_E	0.503	0.24
315_D	350_S	0.502	0.24
75_R	463_A	0.502	0.24
206_G	329_G	0.502	0.24
308_S	319_K	0.502	0.24
183_A	408_K	0.501	0.24
164_I	504_V	0.501	0.24
69_E	81_T	0.501	0.24
408_K	477_V	0.501	0.24
105_Y	166_E	0.500	0.24
197_L	369_S	0.500	0.24

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ofdA	1	0.9086	100	0.517	Contact Map
1ea0A	1	0.9067	100	0.527	Contact Map
2qr6A	3	0.6552	100	0.865	Contact Map
3r2gA	3	0.581	100	0.867	Contact Map
2c6qA	4	0.5905	99.9	0.876	Contact Map
4zqmA	3	0.5714	99.9	0.877	Contact Map
1eepA	4	0.5524	99.9	0.878	Contact Map
1p0kA	4	0.5676	99.9	0.879	Contact Map
3vkjA	4	0.6286	99.9	0.88	Contact Map
4x3zA	3	0.6286	99.9	0.88	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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