GREMLIN Database
YKOS - Uncharacterized membrane protein YkoS
UniProt: O34830 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 564 (551)
Sequences: 145 (116)
Seq/√Len: 5.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
433_A521_F5.4300.98
186_S228_Y4.4820.94
466_R484_D4.4690.94
72_I452_T4.3490.93
412_A415_Q4.3360.93
412_A555_A3.8950.88
464_E523_K3.6310.84
197_A348_F3.3270.78
521_F526_G3.3010.78
546_V562_E3.2540.77
420_K427_Q3.2330.76
180_G223_F3.2200.76
464_E520_V3.1910.75
250_E463_Y3.1620.74
524_M547_K3.1450.74
211_R413_S3.0330.71
94_F98_T3.0050.70
83_E234_R2.9770.70
211_R355_V2.9740.69
520_V523_K2.7810.64
520_V524_M2.7100.62
416_F445_N2.7080.62
285_L362_L2.6670.60
247_H488_S2.6040.59
169_G216_M2.5560.57
251_F334_K2.5530.57
359_S364_L2.5280.56
52_K56_D2.5190.56
409_E415_Q2.4970.55
468_I521_F2.4720.54
35_D220_S2.4370.53
492_L524_M2.3900.52
228_Y298_K2.3740.51
343_F458_P2.3740.51
418_E474_E2.3680.51
266_I316_Y2.3540.51
249_I338_A2.3530.50
410_F438_H2.3300.50
30_F105_T2.2990.49
415_Q554_S2.2970.49
43_N100_Y2.2860.48
437_L492_L2.2850.48
211_R283_V2.2780.48
35_D408_R2.2720.48
96_S407_F2.2540.47
24_L211_R2.2320.47
261_S265_S2.2280.46
494_V511_I2.2140.46
269_F463_Y2.1750.45
291_V415_Q2.1630.44
47_N50_W2.1330.43
40_V137_S2.0980.42
479_L511_I2.0800.42
122_H165_N2.0780.42
73_N450_L2.0770.42
188_F246_M2.0660.41
15_L22_L2.0570.41
72_I454_N2.0570.41
265_S320_L2.0510.41
34_E408_R2.0390.40
47_N146_W2.0380.40
331_A341_A2.0350.40
483_F490_C2.0090.40
473_L484_D1.9790.39
471_K515_Q1.9600.38
293_A377_L1.9520.38
479_L494_V1.9350.37
437_L532_S1.9210.37
75_L452_T1.9160.37
495_D509_K1.8590.35
406_T520_V1.8570.35
477_S480_K1.8560.35
424_G533_V1.8340.34
431_R448_Y1.8180.34
29_L96_S1.8120.34
377_L539_E1.8110.34
137_S364_L1.7820.33
251_F254_S1.7780.33
517_N524_M1.7530.32
137_S240_L1.7210.31
450_L526_G1.7140.31
296_L299_R1.7120.31
480_K520_V1.6960.30
265_S316_Y1.6890.30
220_S364_L1.6880.30
333_P467_K1.6790.30
166_I179_L1.6690.30
409_E476_N1.6630.29
422_Y549_F1.6580.29
232_E235_L1.6440.29
165_N175_E1.6320.29
269_F288_L1.6150.28
127_P290_V1.5960.28
228_Y532_S1.5900.28
230_F424_G1.5830.27
254_S334_K1.5830.27
420_K460_S1.5770.27
192_F224_M1.5730.27
450_L524_M1.5720.27
545_L548_T1.5700.27
78_D239_M1.5560.27
483_F502_D1.5520.27
461_Y465_F1.5510.27
38_I123_I1.5310.26
290_V519_D1.5300.26
204_L221_I1.5090.26
464_E524_M1.5090.26
232_E456_L1.5060.25
388_V424_G1.4950.25
474_E480_K1.4830.25
160_L164_L1.4780.25
114_G360_F1.4760.25
320_L421_E1.4720.25
44_L230_F1.4700.25
255_R485_E1.4560.24
35_D230_F1.4550.24
419_I558_I1.4550.24
109_V220_S1.4470.24
185_Y351_L1.4460.24
15_L106_V1.4460.24
262_L266_I1.4450.24
344_N349_H1.4390.24
28_P115_M1.4370.24
369_R428_D1.4350.24
294_A521_F1.4300.24
29_L363_A1.4270.24
23_L406_T1.4250.24
457_Y490_C1.3870.23
123_I289_M1.3870.23
298_K380_A1.3800.23
253_S334_K1.3800.23
16_W407_F1.3770.22
29_L394_E1.3760.22
339_F406_T1.3740.22
194_F232_E1.3730.22
94_F102_I1.3640.22
273_H493_F1.3610.22
275_H350_F1.3530.22
80_F414_E1.3440.22
74_G465_F1.3420.22
182_L192_F1.3410.22
547_K560_L1.3360.22
290_V388_V1.3350.22
19_L517_N1.3260.21
415_Q555_A1.3260.21
159_A192_F1.3230.21
84_W137_S1.3220.21
68_I197_A1.3210.21
422_Y560_L1.3130.21
22_L287_I1.3120.21
425_R527_R1.3090.21
75_L454_N1.3090.21
424_G559_Y1.3030.21
298_K545_L1.2950.21
236_V246_M1.2930.21
18_A138_L1.2910.21
482_Y489_R1.2900.21
150_M179_L1.2790.20
200_A364_L1.2730.20
49_A433_A1.2720.20
246_M456_L1.2720.20
219_G542_H1.2720.20
177_L258_V1.2630.20
287_I358_V1.2630.20
292_F300_N1.2590.20
129_A551_H1.2570.20
466_R473_L1.2550.20
136_V415_Q1.2550.20
36_A189_V1.2540.20
207_A213_W1.2470.20
430_Y448_Y1.2420.20
247_H456_L1.2420.20
189_V455_N1.2370.19
367_I470_E1.2320.19
435_I529_I1.2250.19
476_N495_D1.2040.19
76_P378_V1.1980.19
56_D66_A1.1870.18
128_K134_I1.1840.18
80_F154_L1.1780.18
235_L280_H1.1750.18
552_K557_R1.1750.18
137_S283_V1.1710.18
186_S462_K1.1700.18
30_F106_V1.1680.18
470_E524_M1.1670.18
476_N494_V1.1650.18
83_E107_T1.1640.18
239_M334_K1.1630.18
228_Y364_L1.1580.18
220_S427_Q1.1480.18
15_L228_Y1.1460.18
522_K529_I1.1460.18
78_D246_M1.1440.18
41_H345_F1.1420.18
249_I337_F1.1420.18
87_I153_T1.1400.18
183_P234_R1.1380.18
418_E506_N1.1370.18
75_L132_I1.1360.17
199_M220_S1.1350.17
467_K539_E1.1230.17
137_S390_A1.1180.17
91_H142_L1.1150.17
20_F553_D1.1150.17
437_L533_V1.1140.17
269_F513_N1.1000.17
49_A54_L1.0990.17
82_T339_F1.0990.17
134_I524_M1.0980.17
180_G477_S1.0950.17
95_S433_A1.0920.17
346_A352_R1.0900.17
147_P357_Y1.0890.17
417_K548_T1.0880.17
114_G459_L1.0830.17
48_I284_I1.0820.17
15_L548_T1.0780.16
258_V265_S1.0780.16
110_V126_E1.0780.16
74_G461_Y1.0740.16
272_G483_F1.0740.16
39_R146_W1.0730.16
73_N408_R1.0720.16
385_Q458_P1.0660.16
281_T378_V1.0660.16
290_V492_L1.0650.16
517_N529_I1.0630.16
340_L440_S1.0630.16
311_L505_K1.0610.16
483_F553_D1.0600.16
201_C460_S1.0570.16
40_V282_V1.0490.16
292_F519_D1.0480.16
123_I557_R1.0440.16
82_T355_V1.0430.16
143_T154_L1.0430.16
22_L366_L1.0420.16
22_L523_K1.0390.16
359_S363_A1.0390.16
50_W146_W1.0370.16
102_I220_S1.0370.16
68_I179_L1.0370.16
201_C420_K1.0360.16
54_L77_R1.0350.16
239_M254_S1.0350.16
208_I411_Y1.0240.15
101_A269_F1.0230.15
54_L232_E1.0200.15
318_L344_N1.0200.15
377_L381_A1.0170.15
240_L288_L1.0160.15
294_A474_E1.0100.15
12_T299_R1.0070.15
526_G563_T1.0070.15
226_S527_R1.0060.15
260_H274_N1.0040.15
146_W190_L1.0020.15
319_S352_R1.0010.15
319_S360_F1.0010.15
34_E40_V1.0000.15
183_P350_F0.9990.15
220_S552_K0.9970.15
149_G224_M0.9960.15
122_H555_A0.9950.15
85_S232_E0.9940.15
48_I292_F0.9930.15
147_P323_A0.9930.15
12_T215_L0.9910.15
83_E183_P0.9890.15
225_T229_L0.9890.15
146_W149_G0.9870.15
49_A521_F0.9860.15
376_W532_S0.9840.15
209_T283_V0.9820.15
339_F540_Q0.9810.15
22_L558_I0.9740.15
20_F228_Y0.9740.15
175_E471_K0.9740.15
212_R320_L0.9720.15
449_T465_F0.9720.15
162_A497_L0.9700.15
96_S301_R0.9700.15
456_L488_S0.9690.15
91_H532_S0.9680.15
212_R261_S0.9660.15
183_P233_Y0.9660.15
85_S521_F0.9610.14
550_D557_R0.9560.14
212_R471_K0.9560.14
393_N542_H0.9540.14
149_G319_S0.9520.14
23_L136_V0.9490.14
56_D59_E0.9480.14
132_I407_F0.9480.14
192_F203_W0.9460.14
192_F323_A0.9430.14
334_K367_I0.9420.14
117_V125_P0.9420.14
134_I386_L0.9420.14
422_Y546_V0.9390.14
428_D494_V0.9380.14
143_T356_I0.9380.14
113_F476_N0.9340.14
247_H324_F0.9330.14
200_A381_A0.9330.14
293_A540_Q0.9320.14
299_R375_K0.9320.14
205_Y209_T0.9320.14
518_T550_D0.9240.14
388_V408_R0.9210.14
357_Y501_Y0.9210.14
250_E556_W0.9200.14
372_K522_K0.9200.14
227_I394_E0.9160.14
143_T156_Y0.9140.14
49_A440_S0.9130.14
343_F349_H0.9130.14
286_P322_Y0.9100.14
250_E351_L0.9100.14
229_L529_I0.9090.14
196_L259_W0.9080.14
40_V174_R0.9060.14
39_R148_S0.9040.14
505_K547_K0.9020.14
319_S344_N0.9010.14
163_F224_M0.8980.13
350_F537_N0.8980.13
422_Y547_K0.8920.13
230_F542_H0.8850.13
54_L89_W0.8840.13
477_S495_D0.8830.13
17_I126_E0.8820.13
252_I460_S0.8800.13
47_N190_L0.8800.13
121_K124_I0.8740.13
268_N349_H0.8740.13
69_P188_F0.8730.13
288_L463_Y0.8720.13
87_I185_Y0.8710.13
120_K305_E0.8700.13
505_K549_F0.8690.13
152_S549_F0.8660.13
433_A542_H0.8630.13
128_K547_K0.8620.13
23_L290_V0.8610.13
265_S323_A0.8600.13
93_F222_A0.8590.13
44_L355_V0.8590.13
58_G106_V0.8570.13
116_Y385_Q0.8570.13
184_L228_Y0.8570.13
269_F363_A0.8540.13
25_Y395_E0.8510.13
470_E494_V0.8510.13
23_L524_M0.8480.13
193_F558_I0.8470.13
468_I526_G0.8470.13
38_I97_M0.8440.13
299_R460_S0.8440.13
406_T418_E0.8440.13
24_L67_A0.8390.13
299_R383_A0.8390.13
97_M407_F0.8390.13
69_P74_G0.8390.13
429_S539_E0.8380.13
155_G228_Y0.8370.13
28_P32_L0.8370.13
47_N149_G0.8360.13
406_T458_P0.8360.13
199_M221_I0.8330.13
171_I175_E0.8310.13
40_V97_M0.8310.13
322_Y449_T0.8310.13
352_R356_I0.8300.12
239_M494_V0.8300.12
115_M152_S0.8300.12
127_P228_Y0.8290.12
449_T461_Y0.8280.12
31_I477_S0.8280.12
177_L222_A0.8270.12
49_A193_F0.8260.12
158_L410_F0.8240.12
23_L230_F0.8210.12
470_E517_N0.8210.12
23_L377_L0.8200.12
340_L492_L0.8170.12
172_S175_E0.8170.12
76_P137_S0.8170.12
275_H530_F0.8150.12
235_L433_A0.8110.12
79_A483_F0.8110.12
261_S382_V0.8090.12
151_L231_V0.8090.12
94_F503_F0.8060.12
149_G192_F0.8050.12
106_V317_G0.8030.12
77_R233_Y0.8010.12
171_I544_A0.8000.12
179_L526_G0.7990.12
211_R506_N0.7960.12
414_E471_K0.7960.12
315_N452_T0.7950.12
154_L161_W0.7940.12
84_W257_D0.7930.12
63_K170_D0.7930.12
408_R517_N0.7920.12
102_I137_S0.7900.12
197_A521_F0.7900.12
20_F375_K0.7890.12
172_S294_A0.7880.12
166_I467_K0.7880.12
242_E313_V0.7870.12
91_H276_V0.7870.12
101_A139_A0.7850.12
406_T517_N0.7840.12
510_T536_M0.7800.12
333_P554_S0.7790.12
107_T348_F0.7790.12
431_R534_P0.7770.12
204_L217_F0.7750.12
210_K220_S0.7740.12
171_I379_Y0.7730.12
117_V161_W0.7720.12
440_S457_Y0.7720.12
265_S408_R0.7710.12
83_E233_Y0.7710.12
237_Y257_D0.7700.12
192_F273_H0.7670.12
159_A182_L0.7660.12
159_A166_I0.7660.12
19_L458_P0.7640.12
215_L413_S0.7640.12
68_I492_L0.7630.12
76_P176_W0.7620.12
91_H184_L0.7620.12
318_L349_H0.7610.12
419_I517_N0.7600.12
274_N398_Y0.7600.12
417_K517_N0.7600.12
96_S109_V0.7590.12
28_P549_F0.7570.11
48_I411_Y0.7570.11
265_S427_Q0.7570.11
141_A144_P0.7560.11
14_Y197_A0.7550.11
94_F224_M0.7550.11
284_I334_K0.7540.11
84_W380_A0.7540.11
137_S178_T0.7530.11
33_K540_Q0.7530.11
422_Y532_S0.7510.11
386_L529_I0.7490.11
20_F80_F0.7490.11
207_A236_V0.7490.11
98_T101_A0.7480.11
239_M338_A0.7470.11
171_I290_V0.7440.11
374_W521_F0.7420.11
177_L333_P0.7420.11
250_E276_V0.7410.11
406_T524_M0.7400.11
160_L196_L0.7400.11
113_F513_N0.7390.11
375_K545_L0.7380.11
331_A474_E0.7380.11
38_I48_I0.7370.11
257_D260_H0.7370.11
89_W94_F0.7360.11
199_M303_K0.7350.11
78_D456_L0.7350.11
276_V356_I0.7340.11
100_Y235_L0.7330.11
192_F315_N0.7320.11
354_L407_F0.7300.11
46_S50_W0.7300.11
40_V287_I0.7300.11
107_T247_H0.7300.11
265_S523_K0.7290.11
135_G413_S0.7280.11
174_R378_V0.7280.11
67_A177_L0.7260.11
197_A201_C0.7250.11
132_I137_S0.7240.11
313_V375_K0.7230.11
237_Y288_L0.7220.11
67_A523_K0.7180.11
384_A413_S0.7170.11
119_L238_S0.7170.11
126_E301_R0.7170.11
71_I435_I0.7140.11
67_A506_N0.7130.11
192_F356_I0.7130.11
413_S539_E0.7130.11
186_S298_K0.7130.11
32_L395_E0.7130.11
192_F195_F0.7130.11
211_R558_I0.7110.11
231_V269_F0.7100.11
53_V213_W0.7100.11
90_L111_A0.7090.11
29_L521_F0.7080.11
18_A173_W0.7080.11
373_G557_R0.7070.11
67_A375_K0.7060.11
230_F306_N0.7060.11
201_C205_Y0.7040.11
23_L129_A0.7030.11
159_A315_N0.7030.11
159_A398_Y0.7020.11
296_L300_N0.7000.11
94_F204_L0.7000.11
155_G191_G0.6980.11
212_R519_D0.6980.11
68_I386_L0.6980.11
127_P563_T0.6960.11
126_E257_D0.6960.11
255_R328_K0.6950.11
222_A367_I0.6950.11
15_L266_I0.6940.11
48_I530_F0.6940.11
39_R50_W0.6930.11
325_W334_K0.6910.11
254_S502_D0.6910.11
44_L354_L0.6910.11
68_I120_K0.6900.11
146_W192_F0.6900.11
195_F233_Y0.6900.11
211_R551_H0.6900.11
384_A485_E0.6890.11
246_M251_F0.6890.11
110_V333_P0.6890.11
35_D58_G0.6890.11
270_V554_S0.6890.11
133_R380_A0.6880.11
94_F290_V0.6880.11
258_V261_S0.6870.11
403_N518_T0.6840.11
312_C359_S0.6840.11
409_E412_A0.6840.11
502_D533_V0.6830.11
296_L563_T0.6820.11
297_F303_K0.6810.11
27_S137_S0.6810.11
166_I217_F0.6810.11
481_Q485_E0.6800.11
31_I540_Q0.6800.11
134_I378_V0.6790.11
131_F522_K0.6790.11
310_F394_E0.6790.11
345_F526_G0.6790.11
108_R344_N0.6790.11
333_P492_L0.6780.10
195_F325_W0.6780.10
244_A247_H0.6770.10
540_Q550_D0.6760.10
76_P132_I0.6750.10
447_F526_G0.6750.10
109_V414_E0.6740.10
215_L553_D0.6730.10
40_V102_I0.6730.10
285_L423_I0.6720.10
175_E317_G0.6700.10
47_N189_V0.6700.10
208_I492_L0.6690.10
424_G450_L0.6690.10
24_L134_I0.6680.10
149_G325_W0.6670.10
244_A406_T0.6670.10
162_A556_W0.6660.10
60_I187_S0.6660.10
17_I261_S0.6650.10
183_P248_R0.6650.10
38_I354_L0.6640.10
80_F327_N0.6640.10
120_K523_K0.6630.10
102_I316_Y0.6630.10
179_L322_Y0.6620.10
353_P491_Y0.6620.10
141_A164_L0.6620.10
287_I384_A0.6620.10
145_F178_T0.6610.10
405_P556_W0.6610.10
76_P163_F0.6580.10
396_Y409_E0.6560.10
311_L521_F0.6550.10
39_R47_N0.6540.10
239_M246_M0.6540.10
154_L426_P0.6530.10
140_F156_Y0.6500.10
468_I563_T0.6500.10
32_L459_L0.6480.10
72_I225_T0.6480.10
483_F544_A0.6480.10
34_E444_Y0.6470.10
351_L463_Y0.6470.10
24_L503_F0.6470.10
126_E373_G0.6470.10
89_W264_L0.6460.10
318_L330_W0.6450.10
49_A504_K0.6450.10
154_L499_K0.6450.10
121_K306_N0.6450.10
62_G91_H0.6430.10
100_Y444_Y0.6430.10
387_M535_I0.6420.10
340_L358_V0.6420.10
120_K367_I0.6410.10
111_A195_F0.6400.10
76_P348_F0.6380.10
201_C240_L0.6380.10
22_L215_L0.6380.10
319_S398_Y0.6360.10
33_K480_K0.6360.10
368_W378_V0.6350.10
77_R232_E0.6350.10
226_S309_L0.6340.10
135_G384_A0.6340.10
111_A234_R0.6340.10
517_N554_S0.6320.10
414_E551_H0.6320.10
23_L399_G0.6300.10
258_V329_I0.6300.10
432_V473_L0.6290.10
251_F511_I0.6290.10
287_I362_L0.6280.10
63_K237_Y0.6270.10
84_W110_V0.6270.10
450_L494_V0.6270.10
211_R408_R0.6260.10
475_K549_F0.6260.10
255_R269_F0.6260.10
161_W356_I0.6240.10
40_V485_E0.6220.10
146_W151_L0.6220.10
468_I524_M0.6220.10
50_W190_L0.6200.10
266_I383_A0.6190.10
214_N526_G0.6180.10
72_I75_L0.6180.10
21_L309_L0.6170.10
218_L354_L0.6170.10
209_T546_V0.6160.10
153_T191_G0.6160.10
294_A460_S0.6150.10
156_Y247_H0.6150.10
470_E522_K0.6150.10
373_G417_K0.6140.10
34_E135_G0.6140.10
339_F470_E0.6120.10
194_F445_N0.6110.10
219_G536_M0.6110.10
303_K414_E0.6110.10
109_V240_L0.6110.10
27_S418_E0.6100.10
144_P430_Y0.6090.10
387_M524_M0.6080.10
196_L228_Y0.6060.10
381_A407_F0.6050.10
209_T562_E0.6050.10
247_H338_A0.6050.10
311_L355_V0.6040.10
254_S407_F0.6040.10
347_R561_Y0.6030.10
24_L201_C0.6030.10
456_L483_F0.6030.10
100_Y416_F0.6030.10
310_F524_M0.6030.10
262_L316_Y0.6020.10
80_F140_F0.6000.10
19_L113_F0.5990.10
156_Y420_K0.5990.10
145_F276_V0.5990.10
248_R462_K0.5970.10
207_A220_S0.5960.10
71_I523_K0.5930.10
426_P513_N0.5920.10
415_Q517_N0.5910.09
146_W189_V0.5910.09
112_F116_Y0.5900.09
146_W443_Q0.5890.09
137_S418_E0.5880.09
45_D118_L0.5860.09
58_G490_C0.5850.09
393_N436_G0.5840.09
83_E191_G0.5840.09
166_I546_V0.5840.09
257_D370_M0.5830.09
56_D269_F0.5830.09
232_E348_F0.5820.09
98_T223_F0.5810.09
104_Q108_R0.5810.09
218_L528_Y0.5800.09
179_L238_S0.5800.09
95_S254_S0.5800.09
247_H256_H0.5790.09
26_V126_E0.5790.09
240_L295_L0.5770.09
189_V483_F0.5760.09
235_L444_Y0.5750.09
256_H327_N0.5750.09
138_L286_P0.5740.09
288_L309_L0.5730.09
32_L560_L0.5730.09
50_W501_Y0.5710.09
239_M470_E0.5710.09
373_G539_E0.5710.09
465_F526_G0.5700.09
91_H103_S0.5700.09
117_V262_L0.5690.09
212_R380_A0.5680.09
35_D314_L0.5670.09
16_W184_L0.5670.09
17_I527_R0.5650.09
342_E456_L0.5650.09
171_I186_S0.5650.09
322_Y456_L0.5640.09
93_F460_S0.5640.09
136_V554_S0.5630.09
155_G442_A0.5620.09
488_S511_I0.5620.09
257_D288_L0.5620.09
350_F530_F0.5610.09
174_R278_T0.5590.09
329_I402_Y0.5590.09
270_V495_D0.5570.09
164_L431_R0.5560.09
44_L71_I0.5560.09
264_L441_I0.5560.09
44_L218_L0.5560.09
355_V429_S0.5560.09
126_E467_K0.5540.09
58_G317_G0.5540.09
386_L545_L0.5530.09
460_S485_E0.5530.09
313_V382_V0.5520.09
129_A562_E0.5520.09
31_I177_L0.5520.09
96_S562_E0.5520.09
342_E556_W0.5520.09
406_T478_R0.5520.09
135_G394_E0.5510.09
159_A179_L0.5510.09
91_H557_R0.5510.09
48_I72_I0.5510.09
439_P451_D0.5510.09
177_L397_T0.5500.09
291_V539_E0.5490.09
22_L292_F0.5490.09
29_L338_A0.5470.09
446_G558_I0.5470.09
191_G318_L0.5440.09
19_L563_T0.5440.09
222_A492_L0.5440.09
37_H217_F0.5410.09
403_N481_Q0.5400.09
482_Y537_N0.5400.09
156_Y324_F0.5400.09
283_V558_I0.5400.09
220_S460_S0.5390.09
312_C364_L0.5390.09
155_G318_L0.5390.09
96_S383_A0.5380.09
69_P412_A0.5370.09
322_Y484_D0.5360.09
373_G527_R0.5350.09
113_F387_M0.5350.09
65_D313_V0.5340.09
69_P555_A0.5340.09
20_F418_E0.5330.09
22_L218_L0.5330.09
42_D45_D0.5320.09
137_S265_S0.5320.09
272_G487_G0.5320.09
71_I121_K0.5320.09
289_M292_F0.5310.09
200_A282_V0.5290.09
223_F540_Q0.5290.09
404_A504_K0.5290.09
392_F420_K0.5280.09
262_L290_V0.5270.09
318_L321_W0.5270.09
184_L495_D0.5250.09
247_H275_H0.5240.09
487_G531_S0.5230.09
263_R290_V0.5220.09
94_F262_L0.5220.09
121_K170_D0.5210.09
224_M286_P0.5210.09
91_H131_F0.5200.09
17_I285_L0.5200.09
184_L231_V0.5200.09
339_F520_V0.5200.09
306_N529_I0.5190.09
151_L505_K0.5190.09
134_I173_W0.5180.09
240_L390_A0.5160.09
256_H337_F0.5160.09
330_W357_Y0.5140.09
114_G549_F0.5130.09
527_R562_E0.5120.09
393_N482_Y0.5100.09
43_N543_L0.5090.09
22_L312_C0.5080.09
126_E309_L0.5070.09
267_K271_Y0.5070.09
121_K382_V0.5070.09
192_F344_N0.5060.09
19_L425_R0.5050.09
193_F236_V0.5050.09
459_L472_E0.5050.09
364_L378_V0.5040.09
132_I378_V0.5040.09
138_L149_G0.5040.09
274_N350_F0.5040.09
143_T426_P0.5030.09
268_N325_W0.5030.09
240_L392_F0.5020.09
123_I372_K0.5020.09
38_I445_N0.5020.09
71_I142_L0.5010.09
112_F165_N0.5010.09
273_H325_W0.5010.09
41_H537_N0.5010.09
437_L516_L0.5010.09
199_M224_M0.5000.09
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3wajA 1 0.7411 82.6 0.979 Contact Map
3rceA 1 0.8316 74.8 0.981 Contact Map
2i8dA 2 0.1791 35.2 0.985 Contact Map
2ehpA 2 0.1826 11.8 0.988 Contact Map
2m8rA 1 0.0656 8.5 0.989 Contact Map
2oc6A 1 0.1844 7.6 0.989 Contact Map
3hd7A 1 0.0585 7.3 0.989 Contact Map
2dt7A 1 0.0674 4.8 0.99 Contact Map
2b4wA 1 0.1986 4.7 0.99 Contact Map
1jx6A 1 0.1933 4.5 0.99 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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