YVKC - BACSU - GREMLIN Contacts

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YVKC - Uncharacterized phosphotransferase YvkC

UniProt:	O34796	Sequences: MYSVLFRQAEESSQLAGAKGMNLIKLTKHGLPVPDGFIIQTNALARFMEDNQLQETSENVEGGIISGTFSDELKDELTSSFYKLRESYRSVAVRSSSASEDLEGASFAGQYETYLNIKTEEEFLAKVKECWASFFSGRVSSYKKKMNNQIAEPLMGIVVQGLIDSEMSGVIFSRNPVTHDDRELLISASYGLGEAVVSGNVTPDTFIVNKSSFEIQKEIGAKEIYMESAAEGIAEKETSEDMRSRFCLTDEQVIELAEITKKTEDLYGYPVDIEFGIADHQIYLLQARPITTIDQDKKAAEEKRSFMITDTDMNDFWLNMESNIEGPVSPLFSSFIVPALEYGLKKSMQKFPIGVVVDEVKLYRGHIYSKNQGGQQPPSEDCGKELFPILSEHMYDIINHTYLPFYRTLDQLAQTEHTAESALEAFQKLKAFYLTAYEEHFNIVFPQILLTNKLQAMYQDIQGESENAHFYEMLTGKMNKSLETDRCLWLFSVEVQENPNLLAIFENNKPEQLQEKLEQTDEGRHFLKNVHEFLQEYGWRSVKSHDLIEQIWVENPYFALANIQNYVRNGYHFDNEFQKTKEKREKLYNEFLESIEDPGLRTEFDRYYQWTLNSANIKDDHHFYIDAMLDAKARIFLLKIGELLAENGVIQDREDLWFLYDDEVEQALLHPVSLQEKAEKRRQIFHEYELAQAPAYLGTPTKEQLKAAEEIVGAVIEDEKNTENHIFGIAASSGIATGPVKIIRDANEFSQFAPGDVLVCKMTTPLWTSLFQDAKAIITDTGGILSHAAIIAREYGIPAVLGTRTATERLRDGDIITVDGSSGKITVVSRS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	831 (765)
Sequences:	1067 (832)
Seq/√Len:	30.1

BACSU - YVKC PPS

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
740_V	810_L	9.392	1.00
175_N	183_E	9.364	1.00
263_T	284_L	8.338	1.00
737_T	817_T	8.046	1.00
776_A	818_V	6.200	1.00
276_G	285_L	5.955	1.00
740_V	816_I	5.074	1.00
20_G	158_V	4.967	1.00
171_I	260_T	4.845	1.00
663_E	681_R	4.644	1.00
757_V	776_A	4.629	1.00
737_T	815_I	4.500	1.00
330_P	658_F	4.402	1.00
25_K	266_L	4.355	1.00
188_A	247_C	3.967	1.00
277_I	282_I	3.883	1.00
800_V	818_V	3.838	1.00
210_K	264_E	3.689	1.00
81_F	91_V	3.657	1.00
249_T	252_Q	3.646	1.00
739_P	815_I	3.554	1.00
171_I	256_L	3.530	1.00
259_I	284_L	3.521	1.00
187_S	205_T	3.503	1.00
37_F	159_V	3.431	1.00
810_L	816_I	3.429	1.00
271_V	287_A	3.350	1.00
817_T	826_T	3.322	1.00
166_E	278_A	3.275	1.00
263_T	273_I	3.274	1.00
208_V	253_V	3.268	1.00
189_S	196_V	3.258	1.00
651_Q	675_Q	3.250	1.00
165_S	276_G	3.226	1.00
92_A	115_L	3.071	1.00
745_D	748_E	3.071	1.00
819_D	822_S	2.987	1.00
780_D	803_T	2.943	1.00
167_M	247_C	2.907	1.00
735_I	817_T	2.907	1.00
46_R	72_E	2.868	1.00
395_Y	398_I	2.788	1.00
741_K	756_D	2.770	1.00
16_A	38_I	2.746	1.00
418_T	421_S	2.716	1.00
639_K	643_L	2.709	1.00
186_I	253_V	2.650	1.00
817_T	828_V	2.615	1.00
173_S	260_T	2.608	1.00
116_N	192_L	2.599	1.00
756_D	812_D	2.593	1.00
656_L	664_V	2.491	0.99
171_I	184_L	2.490	0.99
189_S	195_A	2.410	0.99
642_E	653_R	2.403	0.99
800_V	825_I	2.342	0.99
174_R	181_D	2.326	0.99
35_D	161_G	2.286	0.99
58_E	62_G	2.277	0.99
174_R	290_I	2.268	0.99
81_F	84_L	2.234	0.99
267_Y	287_A	2.138	0.98
39_I	77_L	2.133	0.98
742_I	812_D	2.102	0.98
95_S	106_S	2.090	0.98
740_V	778_I	2.070	0.98
69_F	124_L	2.063	0.98
51_N	67_G	2.063	0.98
447_Q	450_L	2.042	0.97
332_F	546_D	2.027	0.97
263_T	287_A	1.994	0.97
170_V	189_S	1.973	0.97
811_R	814_D	1.939	0.96
139_V	143_K	1.925	0.96
658_F	682_R	1.920	0.96
757_V	816_I	1.909	0.96
503_A	507_N	1.889	0.96
119_T	122_E	1.877	0.96
21_M	25_K	1.840	0.95
770_L	774_A	1.836	0.95
206_F	253_V	1.824	0.95
755_G	775_K	1.821	0.95
194_E	198_S	1.808	0.95
544_S	622_H	1.799	0.95
394_M	398_I	1.795	0.95
81_F	85_R	1.788	0.94
366_H	370_K	1.785	0.94
544_S	801_L	1.769	0.94
739_P	756_D	1.762	0.94
126_K	129_E	1.760	0.94
174_R	293_I	1.754	0.94
163_I	276_G	1.751	0.94
113_T	285_L	1.730	0.93
76_E	682_R	1.711	0.93
99_S	102_L	1.709	0.93
458_Y	462_Q	1.706	0.93
62_G	66_S	1.706	0.93
491_F	526_F	1.705	0.93
735_I	819_D	1.705	0.93
25_K	28_K	1.703	0.93
394_M	397_I	1.701	0.93
340_L	625_I	1.698	0.93
509_K	512_Q	1.688	0.92
774_A	777_I	1.683	0.92
257_A	657_W	1.668	0.92
213_F	254_I	1.666	0.92
800_V	820_G	1.646	0.92
114_Y	126_K	1.631	0.91
100_E	108_A	1.613	0.91
81_F	123_F	1.613	0.91
45_A	154_L	1.609	0.91
111_Y	139_V	1.608	0.91
19_K	23_L	1.592	0.90
736_A	776_A	1.583	0.90
32_P	259_I	1.563	0.89
777_I	788_A	1.562	0.89
114_Y	129_E	1.554	0.89
763_T	767_W	1.553	0.89
495_V	526_F	1.553	0.89
209_N	212_S	1.551	0.89
480_K	484_T	1.549	0.89
546_D	788_A	1.548	0.89
46_R	51_N	1.541	0.89
699_T	765_P	1.539	0.88
20_G	27_T	1.533	0.88
815_I	828_V	1.531	0.88
552_W	783_G	1.516	0.88
246_F	253_V	1.507	0.87
239_S	242_M	1.503	0.87
203_P	783_G	1.501	0.87
39_I	73_L	1.501	0.87
622_H	801_L	1.484	0.87
113_T	290_I	1.477	0.86
112_E	138_R	1.474	0.86
481_S	484_T	1.468	0.86
322_S	325_E	1.464	0.86
537_Y	623_F	1.464	0.86
384_K	398_I	1.452	0.85
84_L	91_V	1.450	0.85
29_H	32_P	1.446	0.85
760_C	774_A	1.446	0.85
17_G	23_L	1.442	0.85
776_A	810_L	1.438	0.85
372_Q	375_Q	1.436	0.85
255_E	281_Q	1.433	0.85
98_A	153_P	1.431	0.84
739_P	757_V	1.430	0.84
365_G	368_Y	1.423	0.84
208_V	257_A	1.421	0.84
239_S	243_R	1.419	0.84
328_V	333_S	1.413	0.84
645_A	653_R	1.412	0.84
786_S	790_I	1.409	0.84
546_D	783_G	1.409	0.84
173_S	256_L	1.406	0.83
487_C	536_E	1.396	0.83
110_Q	791_I	1.395	0.83
385_E	388_P	1.393	0.83
115_L	192_L	1.390	0.83
331_L	664_V	1.390	0.83
746_A	760_C	1.388	0.83
659_L	681_R	1.376	0.82
426_F	429_L	1.368	0.82
175_N	207_I	1.367	0.82
554_E	638_L	1.367	0.82
622_H	626_D	1.366	0.82
803_T	825_I	1.357	0.81
99_S	111_Y	1.352	0.81
101_D	108_A	1.350	0.81
737_T	826_T	1.340	0.80
457_M	461_I	1.340	0.80
322_S	332_F	1.335	0.80
622_H	764_T	1.330	0.80
317_W	320_M	1.320	0.79
22_N	271_V	1.307	0.79
250_D	290_I	1.306	0.79
44_L	135_F	1.304	0.78
176_P	793_R	1.297	0.78
526_F	530_V	1.297	0.78
188_A	204_D	1.297	0.78
10_E	25_K	1.295	0.78
780_D	788_A	1.294	0.78
301_E	313_M	1.289	0.78
686_H	689_E	1.288	0.78
500_N	735_I	1.287	0.77
740_V	759_V	1.286	0.77
780_D	804_R	1.279	0.77
206_F	247_C	1.279	0.77
273_I	284_L	1.279	0.77
332_F	481_S	1.274	0.77
42_N	45_A	1.266	0.76
15_L	42_N	1.265	0.76
71_D	74_K	1.265	0.76
623_F	765_P	1.261	0.76
740_V	776_A	1.261	0.76
122_E	125_A	1.258	0.76
383_G	386_L	1.257	0.76
540_R	544_S	1.253	0.76
540_R	801_L	1.248	0.75
93_V	117_I	1.247	0.75
175_N	275_F	1.242	0.75
778_I	810_L	1.239	0.75
391_S	394_M	1.237	0.75
102_L	148_N	1.233	0.74
111_Y	143_K	1.229	0.74
75_D	79_S	1.228	0.74
780_D	805_T	1.226	0.74
734_G	823_G	1.223	0.74
726_I	803_T	1.221	0.74
89_R	161_G	1.220	0.74
786_S	789_A	1.215	0.73
20_G	111_Y	1.214	0.73
37_F	80_S	1.213	0.73
100_E	106_S	1.213	0.73
740_V	758_L	1.212	0.73
334_S	660_Y	1.212	0.73
102_L	111_Y	1.210	0.73
264_E	270_P	1.209	0.73
74_K	124_L	1.208	0.73
778_I	825_I	1.203	0.72
813_G	823_G	1.199	0.72
18_A	158_V	1.195	0.72
481_S	485_D	1.194	0.72
62_G	65_I	1.189	0.72
453_K	603_E	1.189	0.72
325_E	332_F	1.189	0.72
641_G	654_E	1.188	0.72
279_D	654_E	1.187	0.71
73_L	77_L	1.186	0.71
319_N	544_S	1.184	0.71
97_S	111_Y	1.175	0.71
290_I	736_A	1.172	0.70
19_K	34_P	1.170	0.70
323_N	545_H	1.167	0.70
185_L	207_I	1.164	0.70
774_A	791_I	1.161	0.70
117_I	155_M	1.159	0.70
190_Y	204_D	1.158	0.70
615_A	776_A	1.156	0.69
106_S	794_E	1.154	0.69
190_Y	243_R	1.153	0.69
40_Q	43_A	1.152	0.69
622_H	731_A	1.148	0.69
47_F	235_E	1.142	0.68
793_R	823_G	1.142	0.68
323_N	622_H	1.141	0.68
169_G	794_E	1.140	0.68
329_S	546_D	1.139	0.68
321_E	765_P	1.133	0.68
546_D	622_H	1.128	0.67
260_T	273_I	1.127	0.67
501_L	526_F	1.121	0.67
367_I	547_L	1.120	0.67
90_S	118_K	1.117	0.67
263_T	267_Y	1.115	0.67
461_I	464_E	1.111	0.66
48_M	59_N	1.110	0.66
242_M	245_R	1.106	0.66
169_G	199_G	1.106	0.66
483_E	486_R	1.104	0.66
278_A	283_Y	1.102	0.66
238_T	242_M	1.102	0.66
59_N	63_G	1.100	0.65
134_F	143_K	1.099	0.65
580_T	583_K	1.098	0.65
783_G	788_A	1.095	0.65
238_T	243_R	1.094	0.65
337_V	342_Y	1.093	0.65
98_A	102_L	1.093	0.65
787_H	794_E	1.091	0.65
320_M	545_H	1.089	0.65
805_T	809_R	1.089	0.65
51_N	64_I	1.085	0.64
68_T	128_K	1.085	0.64
393_H	397_I	1.082	0.64
85_R	91_V	1.079	0.64
47_F	67_G	1.079	0.64
113_T	194_E	1.075	0.64
165_S	168_S	1.074	0.64
14_Q	75_D	1.074	0.64
168_S	244_S	1.068	0.63
483_E	487_C	1.068	0.63
389_I	398_I	1.066	0.63
113_T	429_L	1.066	0.63
319_N	322_S	1.065	0.63
23_L	34_P	1.063	0.63
167_M	252_Q	1.062	0.63
16_A	20_G	1.062	0.63
50_D	63_G	1.060	0.63
594_S	682_R	1.055	0.62
125_A	129_E	1.052	0.62
541_S	622_H	1.051	0.62
18_A	771_F	1.051	0.62
746_A	774_A	1.049	0.62
173_S	619_D	1.048	0.62
10_E	21_M	1.047	0.62
155_M	776_A	1.043	0.61
322_S	786_S	1.041	0.61
387_F	390_L	1.039	0.61
368_Y	372_Q	1.038	0.61
60_V	64_I	1.036	0.61
78_T	120_E	1.033	0.61
252_Q	656_L	1.033	0.61
584_R	588_Y	1.033	0.61
190_Y	238_T	1.032	0.60
17_G	34_P	1.029	0.60
248_L	252_Q	1.029	0.60
452_N	455_Q	1.028	0.60
537_Y	770_L	1.027	0.60
390_L	394_M	1.027	0.60
73_L	78_T	1.024	0.60
95_S	100_E	1.015	0.59
625_I	783_G	1.014	0.59
501_L	825_I	1.011	0.59
60_V	66_S	1.011	0.59
622_H	785_L	1.011	0.59
545_H	629_L	1.010	0.59
78_T	123_F	1.009	0.59
642_E	646_E	1.008	0.59
820_G	823_G	1.006	0.58
60_V	63_G	1.005	0.58
533_F	552_W	1.005	0.58
204_D	248_L	1.005	0.58
64_I	650_I	1.004	0.58
751_Q	812_D	1.003	0.58
814_D	827_V	1.002	0.58
82_Y	120_E	1.001	0.58
447_Q	454_L	1.001	0.58
453_K	462_Q	0.999	0.58
116_N	170_V	0.999	0.58
196_V	203_P	0.998	0.58
764_T	780_D	0.998	0.58
655_D	678_A	0.998	0.58
340_L	374_G	0.998	0.58
385_E	389_I	0.996	0.58
658_F	685_F	0.995	0.58
325_E	545_H	0.994	0.58
59_N	62_G	0.992	0.57
778_I	816_I	0.989	0.57
741_K	812_D	0.988	0.57
650_I	653_R	0.987	0.57
736_A	757_V	0.986	0.57
818_V	825_I	0.986	0.57
75_D	582_E	0.982	0.57
323_N	544_S	0.979	0.56
167_M	204_D	0.976	0.56
19_K	33_V	0.976	0.56
759_V	810_L	0.974	0.56
77_L	82_Y	0.973	0.56
198_S	290_I	0.973	0.56
184_L	257_A	0.969	0.56
328_V	625_I	0.968	0.55
113_T	189_S	0.968	0.55
381_D	389_I	0.967	0.55
555_N	558_F	0.967	0.55
100_E	272_D	0.967	0.55
325_E	762_M	0.962	0.55
540_R	626_D	0.962	0.55
388_P	391_S	0.961	0.55
322_S	621_H	0.957	0.55
46_R	49_E	0.957	0.55
92_A	193_G	0.957	0.55
16_A	156_G	0.956	0.55
504_I	664_V	0.955	0.54
16_A	40_Q	0.955	0.54
317_W	322_S	0.953	0.54
17_G	20_G	0.951	0.54
383_G	391_S	0.947	0.54
94_R	109_G	0.945	0.54
45_A	71_D	0.945	0.54
148_N	153_P	0.945	0.54
622_H	766_L	0.944	0.54
586_K	589_N	0.943	0.54
391_S	397_I	0.942	0.53
23_L	106_S	0.942	0.53
737_T	828_V	0.939	0.53
10_E	16_A	0.938	0.53
321_E	545_H	0.938	0.53
99_S	153_P	0.932	0.53
585_E	676_E	0.930	0.52
255_E	280_H	0.929	0.52
111_Y	155_M	0.928	0.52
623_F	699_T	0.926	0.52
50_D	71_D	0.925	0.52
374_G	625_I	0.925	0.52
94_R	101_D	0.924	0.52
529_N	532_E	0.922	0.52
20_G	23_L	0.921	0.52
679_E	683_Q	0.921	0.52
500_N	646_E	0.919	0.52
123_F	754_P	0.917	0.51
37_F	84_L	0.917	0.51
76_E	79_S	0.916	0.51
544_S	626_D	0.916	0.51
62_G	281_Q	0.916	0.51
258_E	777_I	0.914	0.51
95_S	169_G	0.914	0.51
391_S	395_Y	0.912	0.51
493_V	559_A	0.910	0.51
329_S	548_I	0.910	0.51
290_I	722_T	0.907	0.51
748_E	751_Q	0.907	0.51
383_G	393_H	0.906	0.51
763_T	791_I	0.905	0.51
68_T	76_E	0.905	0.51
13_S	21_M	0.905	0.51
329_S	685_F	0.904	0.50
545_H	626_D	0.903	0.50
614_S	623_F	0.902	0.50
323_N	795_Y	0.901	0.50
186_I	248_L	0.900	0.50
66_S	519_Q	0.895	0.50
187_S	199_G	0.895	0.50
252_Q	277_I	0.895	0.50
106_S	764_T	0.893	0.50
204_D	247_C	0.893	0.50
23_L	95_S	0.892	0.49
114_Y	664_V	0.891	0.49
639_K	642_E	0.891	0.49
455_Q	563_I	0.890	0.49
332_F	622_H	0.890	0.49
119_T	139_V	0.890	0.49
272_D	288_R	0.889	0.49
544_S	551_I	0.888	0.49
768_T	774_A	0.886	0.49
324_I	786_S	0.885	0.49
18_A	755_G	0.882	0.49
114_Y	130_C	0.882	0.49
166_E	654_E	0.882	0.49
193_G	197_V	0.881	0.49
819_D	824_K	0.880	0.49
389_I	393_H	0.879	0.48
340_L	630_D	0.879	0.48
113_T	417_H	0.875	0.48
553_V	630_D	0.870	0.48
741_K	753_A	0.870	0.48
786_S	802_G	0.870	0.48
206_F	246_F	0.869	0.48
511_E	744_R	0.869	0.48
259_I	263_T	0.868	0.48
778_I	806_A	0.865	0.47
114_Y	117_I	0.864	0.47
693_A	697_L	0.864	0.47
779_T	788_A	0.863	0.47
97_S	134_F	0.862	0.47
197_V	763_T	0.862	0.47
324_I	545_H	0.860	0.47
111_Y	153_P	0.860	0.47
116_N	195_A	0.859	0.47
793_R	813_G	0.858	0.47
164_D	278_A	0.858	0.47
386_L	394_M	0.857	0.47
36_G	788_A	0.857	0.47
638_L	657_W	0.857	0.47
192_L	768_T	0.856	0.47
94_R	100_E	0.856	0.47
728_G	823_G	0.856	0.47
671_P	675_Q	0.855	0.47
769_S	791_I	0.855	0.47
366_H	375_Q	0.855	0.47
44_L	189_S	0.854	0.46
79_S	258_E	0.854	0.46
736_A	810_L	0.852	0.46
168_S	276_G	0.852	0.46
173_S	730_A	0.850	0.46
281_Q	776_A	0.848	0.46
65_I	129_E	0.847	0.46
370_K	375_Q	0.847	0.46
768_T	771_F	0.847	0.46
45_A	50_D	0.846	0.46
415_T	648_G	0.845	0.46
619_D	622_H	0.845	0.46
235_E	239_S	0.844	0.46
388_P	392_E	0.843	0.46
373_G	378_P	0.843	0.46
256_L	282_I	0.842	0.46
236_K	241_D	0.839	0.45
532_E	535_Q	0.837	0.45
199_G	794_E	0.835	0.45
443_I	730_A	0.833	0.45
546_D	551_I	0.833	0.45
385_E	398_I	0.832	0.45
20_G	38_I	0.831	0.45
383_G	388_P	0.830	0.45
117_I	570_G	0.829	0.44
752_F	756_D	0.829	0.44
655_D	682_R	0.828	0.44
60_V	589_N	0.828	0.44
110_Q	293_I	0.826	0.44
17_G	33_V	0.826	0.44
659_L	678_A	0.825	0.44
323_N	546_D	0.825	0.44
101_D	109_G	0.824	0.44
319_N	332_F	0.824	0.44
74_K	78_T	0.821	0.44
129_E	755_G	0.821	0.44
113_T	683_Q	0.820	0.44
615_A	626_D	0.820	0.44
561_A	641_G	0.817	0.44
366_H	779_T	0.817	0.44
382_C	393_H	0.816	0.43
728_G	793_R	0.815	0.43
734_G	820_G	0.815	0.43
143_K	188_A	0.815	0.43
58_E	65_I	0.814	0.43
754_P	775_K	0.814	0.43
753_A	756_D	0.813	0.43
394_M	766_L	0.813	0.43
540_R	622_H	0.812	0.43
196_V	786_S	0.811	0.43
734_G	793_R	0.810	0.43
539_W	771_F	0.810	0.43
634_R	638_L	0.810	0.43
493_V	502_L	0.809	0.43
764_T	803_T	0.804	0.43
728_G	734_G	0.804	0.43
551_I	622_H	0.803	0.42
91_V	127_V	0.802	0.42
752_F	770_L	0.802	0.42
450_L	660_Y	0.800	0.42
142_Y	763_T	0.798	0.42
253_V	257_A	0.796	0.42
622_H	765_P	0.795	0.42
544_S	619_D	0.794	0.42
638_L	653_R	0.792	0.42
45_A	48_M	0.792	0.42
380_E	391_S	0.792	0.42
680_K	684_I	0.791	0.42
505_F	513_L	0.791	0.42
346_K	825_I	0.787	0.41
253_V	493_V	0.787	0.41
530_V	560_L	0.786	0.41
339_A	625_I	0.785	0.41
46_R	73_L	0.784	0.41
744_R	750_S	0.781	0.41
51_N	255_E	0.779	0.41
734_G	767_W	0.778	0.41
37_F	81_F	0.778	0.41
323_N	801_L	0.778	0.41
61_E	137_G	0.777	0.40
332_F	616_N	0.776	0.40
259_I	282_I	0.776	0.40
540_R	763_T	0.776	0.40
163_I	656_L	0.774	0.40
673_S	676_E	0.774	0.40
256_L	260_T	0.773	0.40
384_K	394_M	0.772	0.40
447_Q	533_F	0.771	0.40
95_S	101_D	0.770	0.40
819_D	826_T	0.770	0.40
386_L	389_I	0.769	0.40
341_E	625_I	0.769	0.40
156_G	170_V	0.768	0.40
552_W	789_A	0.767	0.40
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173_S	184_L	0.766	0.40
417_H	421_S	0.764	0.39
592_L	601_R	0.764	0.39
324_I	541_S	0.763	0.39
316_F	699_T	0.761	0.39
544_S	760_C	0.761	0.39
106_S	169_G	0.761	0.39
166_E	547_L	0.760	0.39
167_M	658_F	0.760	0.39
541_S	630_D	0.759	0.39
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102_L	768_T	0.759	0.39
77_L	124_L	0.758	0.39
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102_L	153_P	0.757	0.39
622_H	783_G	0.755	0.39
175_N	650_I	0.755	0.39
51_N	60_V	0.755	0.39
100_E	109_G	0.754	0.39
63_G	646_E	0.754	0.39
35_D	267_Y	0.753	0.39
384_K	388_P	0.752	0.39
273_I	754_P	0.752	0.39
183_E	207_I	0.751	0.38
322_S	795_Y	0.750	0.38
364_R	370_K	0.750	0.38
325_E	623_F	0.750	0.38
47_F	64_I	0.750	0.38
485_D	489_W	0.749	0.38
279_D	413_A	0.748	0.38
275_F	289_P	0.747	0.38
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369_S	374_G	0.747	0.38
623_F	626_D	0.747	0.38
599_G	603_E	0.746	0.38
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504_I	508_N	0.746	0.38
539_W	546_D	0.745	0.38
541_S	551_I	0.745	0.38
781_T	801_L	0.745	0.38
725_H	825_I	0.745	0.38
780_D	806_A	0.745	0.38
666_Q	670_H	0.744	0.38
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327_P	688_Y	0.744	0.38
340_L	369_S	0.744	0.38
121_E	124_L	0.743	0.38
624_Y	627_A	0.742	0.38
507_N	570_G	0.742	0.38
146_M	682_R	0.742	0.38
164_D	827_V	0.742	0.38
532_E	680_K	0.741	0.38
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264_E	292_T	0.740	0.38
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159_V	742_I	0.739	0.38
803_T	806_A	0.738	0.37
169_G	291_T	0.738	0.37
115_L	162_L	0.737	0.37
319_N	325_E	0.736	0.37
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163_I	555_N	0.734	0.37
102_L	107_F	0.734	0.37
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444_V	448_I	0.733	0.37
767_W	793_R	0.732	0.37
332_F	544_S	0.732	0.37
586_K	821_S	0.732	0.37
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697_L	711_I	0.730	0.37
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101_D	106_S	0.728	0.37
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641_G	645_A	0.727	0.37
26_L	289_P	0.727	0.37
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540_R	623_F	0.725	0.37
575_N	579_K	0.725	0.37
546_D	617_I	0.725	0.37
169_G	275_F	0.724	0.36
201_V	243_R	0.724	0.36
322_S	619_D	0.724	0.36
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12_S	15_L	0.723	0.36
315_D	368_Y	0.723	0.36
392_E	395_Y	0.723	0.36
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100_E	288_R	0.720	0.36
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482_L	486_R	0.718	0.36
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390_L	393_H	0.716	0.36
790_I	797_I	0.715	0.36
24_I	38_I	0.715	0.36
579_K	586_K	0.714	0.36
197_V	767_W	0.713	0.36
521_D	525_H	0.713	0.36
332_F	548_I	0.713	0.36
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322_S	545_H	0.709	0.35
324_I	622_H	0.709	0.35
22_N	31_L	0.709	0.35
762_M	779_T	0.709	0.35
272_D	787_H	0.708	0.35
106_S	618_K	0.708	0.35
742_I	807_T	0.708	0.35
552_W	622_H	0.708	0.35
323_N	548_I	0.708	0.35
69_F	243_R	0.707	0.35
24_I	266_L	0.706	0.35
513_L	520_T	0.705	0.35
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731_A	783_G	0.705	0.35
422_A	643_L	0.704	0.35
622_H	630_D	0.704	0.35
235_E	240_E	0.704	0.35
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188_A	206_F	0.703	0.35
644_L	649_V	0.702	0.35
197_V	272_D	0.702	0.35
241_D	711_I	0.699	0.35
50_D	65_I	0.699	0.35
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20_G	506_E	0.697	0.34
159_V	643_L	0.697	0.34
480_K	483_E	0.695	0.34
580_T	587_L	0.695	0.34
556_P	736_A	0.694	0.34
638_L	789_A	0.693	0.34
366_H	372_Q	0.693	0.34
130_C	203_P	0.691	0.34
171_I	257_A	0.691	0.34
62_G	68_T	0.691	0.34
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495_V	567_V	0.689	0.34
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618_K	622_H	0.685	0.34
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382_C	388_P	0.684	0.34
176_P	792_A	0.683	0.33
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335_F	390_L	0.681	0.33
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139_V	186_I	0.680	0.33
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535_Q	648_G	0.678	0.33
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449_L	453_K	0.678	0.33
181_D	293_I	0.678	0.33
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513_L	516_K	0.673	0.33
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422_A	426_F	0.671	0.33
333_S	362_L	0.671	0.33
99_S	134_F	0.670	0.33
168_S	235_E	0.669	0.33
322_S	546_D	0.668	0.32
72_E	82_Y	0.668	0.32
340_L	487_C	0.668	0.32
211_S	515_E	0.668	0.32
335_F	409_L	0.667	0.32
161_G	650_I	0.666	0.32
15_L	244_S	0.666	0.32
108_A	272_D	0.665	0.32
585_E	589_N	0.665	0.32
734_G	759_V	0.665	0.32
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170_V	272_D	0.662	0.32
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315_D	622_H	0.660	0.32
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267_Y	797_I	0.659	0.32
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326_G	543_K	0.659	0.32
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38_I	182_R	0.657	0.32
393_H	398_I	0.657	0.32
383_G	387_F	0.656	0.32
363_Y	368_Y	0.654	0.31
340_L	607_Y	0.654	0.31
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193_G	763_T	0.653	0.31
132_A	290_I	0.653	0.31
731_A	797_I	0.653	0.31
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111_Y	134_F	0.650	0.31
110_Q	763_T	0.649	0.31
360_V	369_S	0.648	0.31
33_V	36_G	0.648	0.31
484_T	790_I	0.647	0.31
582_E	586_K	0.647	0.31
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165_S	192_L	0.645	0.31
661_D	665_E	0.644	0.31
547_L	578_Q	0.644	0.31
39_I	76_E	0.644	0.31
31_L	273_I	0.643	0.31
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658_F	678_A	0.642	0.31
123_F	661_D	0.642	0.31
461_I	600_L	0.641	0.31
252_Q	255_E	0.641	0.31
451_T	454_L	0.640	0.31
551_I	799_A	0.640	0.31
59_N	240_E	0.639	0.30
119_T	204_D	0.639	0.30
179_H	291_T	0.639	0.30
140_S	730_A	0.639	0.30
657_W	730_A	0.638	0.30
329_S	332_F	0.637	0.30
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122_E	240_E	0.636	0.30
319_N	324_I	0.635	0.30
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342_Y	345_K	0.635	0.30
337_V	341_E	0.635	0.30
778_I	818_V	0.635	0.30
326_G	331_L	0.635	0.30
332_F	626_D	0.634	0.30
147_N	281_Q	0.634	0.30
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245_R	500_N	0.633	0.30
58_E	82_Y	0.633	0.30
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782_G	787_H	0.633	0.30
328_V	336_I	0.633	0.30
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275_F	769_S	0.632	0.30
665_E	669_L	0.632	0.30
142_Y	820_G	0.630	0.30
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805_T	808_E	0.629	0.30
666_Q	669_L	0.629	0.30
536_E	819_D	0.628	0.30
500_N	511_E	0.627	0.30
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173_S	277_I	0.623	0.29
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584_R	605_D	0.619	0.29
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647_N	651_Q	0.612	0.29
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637_L	661_D	0.601	0.28
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539_W	783_G	0.589	0.27
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130_C	204_D	0.585	0.27
158_V	162_L	0.584	0.27
384_K	393_H	0.584	0.27
447_Q	611_T	0.584	0.27
552_W	629_L	0.584	0.27
66_S	74_K	0.584	0.27
444_V	447_Q	0.583	0.27
332_F	540_R	0.583	0.27
66_S	71_D	0.582	0.27
104_G	263_T	0.581	0.27
122_E	249_T	0.581	0.27
187_S	788_A	0.581	0.27
18_A	23_L	0.580	0.27
39_I	123_F	0.580	0.27
440_H	788_A	0.580	0.27
366_H	371_N	0.580	0.27
127_V	330_P	0.580	0.27
102_L	263_T	0.579	0.27
271_V	492_S	0.579	0.27
370_K	544_S	0.579	0.27
69_F	73_L	0.579	0.27
335_F	340_L	0.578	0.26
64_I	140_S	0.578	0.26
323_N	783_G	0.578	0.26
328_V	344_L	0.577	0.26
29_H	171_I	0.576	0.26
544_S	623_F	0.576	0.26
48_M	64_I	0.576	0.26
734_G	738_G	0.575	0.26
389_I	394_M	0.574	0.26
95_S	199_G	0.574	0.26
51_N	62_G	0.573	0.26
740_V	796_G	0.573	0.26
46_R	171_I	0.573	0.26
738_G	812_D	0.573	0.26
79_S	121_E	0.572	0.26
327_P	548_I	0.572	0.26
49_E	59_N	0.572	0.26
14_Q	66_S	0.571	0.26
481_S	768_T	0.571	0.26
165_S	193_G	0.570	0.26
297_K	301_E	0.570	0.26
383_G	389_I	0.570	0.26
60_V	263_T	0.567	0.26
771_F	774_A	0.566	0.26
375_Q	625_I	0.566	0.26
60_V	65_I	0.566	0.26
332_F	795_Y	0.566	0.26
792_A	799_A	0.565	0.26
142_Y	197_V	0.565	0.26
388_P	396_D	0.565	0.26
365_G	372_Q	0.564	0.26
334_S	478_M	0.564	0.26
97_S	807_T	0.564	0.26
174_R	294_D	0.564	0.26
275_F	291_T	0.563	0.26
332_F	801_L	0.562	0.26
546_D	780_D	0.562	0.26
85_R	210_K	0.561	0.25
170_V	197_V	0.561	0.25
605_D	609_Q	0.559	0.25
771_F	779_T	0.559	0.25
473_M	477_K	0.558	0.25
117_I	723_E	0.558	0.25
36_G	783_G	0.558	0.25
550_Q	654_E	0.558	0.25
234_A	241_D	0.558	0.25
113_T	182_R	0.556	0.25
762_M	801_L	0.555	0.25
280_H	653_R	0.555	0.25
539_W	623_F	0.555	0.25
779_T	803_T	0.555	0.25
61_E	136_S	0.555	0.25
578_Q	582_E	0.555	0.25
140_S	143_K	0.554	0.25
16_A	24_I	0.554	0.25
651_Q	678_A	0.554	0.25
139_V	256_L	0.552	0.25
44_L	102_L	0.551	0.25
78_T	82_Y	0.551	0.25
187_S	545_H	0.551	0.25
247_C	253_V	0.550	0.25
381_D	387_F	0.550	0.25
367_I	374_G	0.550	0.25
323_N	625_I	0.548	0.25
320_M	325_E	0.548	0.25
99_S	103_E	0.548	0.25
323_N	765_P	0.548	0.25
191_G	823_G	0.548	0.25
60_V	136_S	0.548	0.25
121_E	392_E	0.548	0.25
591_F	672_V	0.547	0.25
61_E	163_I	0.547	0.25
782_G	786_S	0.547	0.25
107_F	138_R	0.547	0.25
327_P	627_A	0.547	0.25
176_P	734_G	0.545	0.25
170_V	196_V	0.545	0.25
317_W	545_H	0.545	0.25
315_D	370_K	0.544	0.24
50_D	244_S	0.544	0.24
41_T	44_L	0.544	0.24
316_F	545_H	0.544	0.24
96_S	100_E	0.543	0.24
567_V	678_A	0.543	0.24
728_G	813_G	0.542	0.24
545_H	619_D	0.542	0.24
14_Q	28_K	0.542	0.24
579_K	583_K	0.542	0.24
158_V	194_E	0.542	0.24
385_E	395_Y	0.541	0.24
121_E	125_A	0.541	0.24
14_Q	27_T	0.541	0.24
23_L	291_T	0.541	0.24
264_E	670_H	0.540	0.24
324_I	731_A	0.540	0.24
161_G	278_A	0.540	0.24
453_K	738_G	0.540	0.24
113_T	753_A	0.540	0.24
618_K	771_F	0.540	0.24
531_H	646_E	0.539	0.24
416_E	431_A	0.539	0.24
482_L	601_R	0.538	0.24
77_L	410_D	0.538	0.24
744_R	748_E	0.538	0.24
253_V	410_D	0.538	0.24
780_D	793_R	0.538	0.24
291_T	767_W	0.537	0.24
168_S	183_E	0.537	0.24
746_A	779_T	0.537	0.24
424_E	495_V	0.537	0.24
461_I	607_Y	0.537	0.24
173_S	478_M	0.536	0.24
92_A	113_T	0.536	0.24
43_A	335_F	0.536	0.24
366_H	436_A	0.535	0.24
473_M	611_T	0.534	0.24
106_S	791_I	0.534	0.24
31_L	263_T	0.533	0.24
190_Y	239_S	0.532	0.24
333_S	344_L	0.532	0.24
317_W	801_L	0.532	0.24
25_K	180_D	0.532	0.24
321_E	785_L	0.532	0.24
337_V	340_L	0.532	0.24
541_S	544_S	0.531	0.24
21_M	262_K	0.531	0.24
386_L	390_L	0.531	0.24
321_E	623_F	0.531	0.24
60_V	140_S	0.530	0.24
625_I	630_D	0.530	0.24
180_D	354_G	0.530	0.24
742_I	806_A	0.530	0.24
393_H	396_D	0.529	0.24
366_H	622_H	0.529	0.24
771_F	788_A	0.528	0.24
484_T	533_F	0.528	0.24
64_I	71_D	0.528	0.24
162_L	190_Y	0.528	0.24
62_G	71_D	0.528	0.24
18_A	791_I	0.527	0.23
625_I	629_L	0.527	0.23
125_A	757_V	0.526	0.23
493_V	496_Q	0.526	0.23
175_N	184_L	0.526	0.23
36_G	546_D	0.526	0.23
14_Q	811_R	0.526	0.23
427_Q	536_E	0.525	0.23
325_E	543_K	0.525	0.23
159_V	411_Q	0.524	0.23
766_L	780_D	0.524	0.23
192_L	195_A	0.524	0.23
368_Y	697_L	0.524	0.23
623_F	802_G	0.524	0.23
314_N	622_H	0.523	0.23
333_S	370_K	0.523	0.23
536_E	648_G	0.523	0.23
511_E	519_Q	0.523	0.23
726_I	780_D	0.522	0.23
69_F	76_E	0.522	0.23
15_L	50_D	0.522	0.23
673_S	677_K	0.521	0.23
16_A	80_S	0.520	0.23
664_V	759_V	0.520	0.23
58_E	163_I	0.520	0.23
39_I	287_A	0.520	0.23
294_D	322_S	0.519	0.23
339_A	428_K	0.519	0.23
672_V	740_V	0.519	0.23
634_R	823_G	0.519	0.23
244_S	281_Q	0.519	0.23
541_S	764_T	0.518	0.23
710_E	777_I	0.518	0.23
42_N	284_L	0.518	0.23
669_L	683_Q	0.518	0.23
38_I	137_G	0.518	0.23
97_S	293_I	0.517	0.23
370_K	391_S	0.517	0.23
188_A	556_P	0.517	0.23
47_F	140_S	0.517	0.23
68_T	247_C	0.517	0.23
756_D	791_I	0.517	0.23
529_N	727_F	0.516	0.23
95_S	109_G	0.516	0.23
122_E	532_E	0.516	0.23
484_T	622_H	0.515	0.23
615_A	789_A	0.515	0.23
72_E	285_L	0.515	0.23
731_A	784_I	0.514	0.23
47_F	51_N	0.514	0.23
70_S	139_V	0.513	0.23
122_E	720_K	0.513	0.23
120_E	123_F	0.512	0.23
490_L	757_V	0.512	0.23
12_S	47_F	0.511	0.23
589_N	646_E	0.511	0.23
729_I	779_T	0.510	0.23
70_S	711_I	0.510	0.23
588_Y	756_D	0.510	0.23
159_V	281_Q	0.510	0.23
85_R	119_T	0.510	0.23
107_F	767_W	0.510	0.23
545_H	552_W	0.510	0.23
638_L	652_D	0.509	0.22
316_F	319_N	0.508	0.22
251_E	748_E	0.508	0.22
243_R	246_F	0.507	0.22
69_F	77_L	0.506	0.22
323_N	366_H	0.506	0.22
433_Y	436_A	0.506	0.22
79_S	280_H	0.506	0.22
767_W	791_I	0.506	0.22
757_V	766_L	0.506	0.22
110_Q	484_T	0.505	0.22
618_K	741_K	0.505	0.22
316_F	322_S	0.505	0.22
622_H	788_A	0.505	0.22
284_L	564_Q	0.505	0.22
540_R	767_W	0.504	0.22
136_S	192_L	0.503	0.22
459_Q	658_F	0.503	0.22
44_L	98_A	0.502	0.22
322_S	484_T	0.502	0.22
642_E	811_R	0.502	0.22
652_D	748_E	0.501	0.22
124_L	127_V	0.501	0.22
410_D	775_K	0.500	0.22
550_Q	558_F	0.500	0.22

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2olsA	2	0.4404	100	0.54	Contact Map
1vbgA	2	0.4874	100	0.648	Contact Map
2x0sA	2	0.5138	100	0.651	Contact Map
1kblA	2	0.4729	100	0.663	Contact Map
2e28A	3	0.6582	99.9	0.89	Contact Map
3t05A	3	0.657	99.9	0.89	Contact Map
1zymA	2	0.2756	99.9	0.897	Contact Map
2hwgA	2	0.2647	99.9	0.901	Contact Map
2wqdA	2	0.2732	99.9	0.903	Contact Map
2hi6A	1	0.1239	98.3	0.959	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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