GREMLIN Database
YDJI - Uncharacterized protein YdjI
UniProt: O34789 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 323 (294)
Sequences: 1026 (756)
Seq/√Len: 44.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
250_S253_M7.0441.00
237_N241_Q5.0111.00
38_I62_D4.2211.00
218_Q222_D3.7961.00
246_D249_A3.6811.00
41_P60_D3.6241.00
120_M177_M3.4111.00
222_D226_K3.3721.00
125_N212_M3.1501.00
235_D238_R2.9171.00
101_V130_F2.8191.00
133_Q205_T2.7171.00
185_F194_D2.7151.00
94_V132_V2.6901.00
52_R140_D2.3491.00
22_I132_V2.3281.00
251_G254_S2.3261.00
44_D135_Y2.2941.00
36_R62_D2.2641.00
162_L209_F2.2621.00
132_V138_L2.1981.00
258_A261_D2.1681.00
131_K205_T2.1601.00
46_V94_V2.0750.99
220_V225_T2.0670.99
130_F151_V2.0430.99
240_Q245_T2.0310.99
183_N186_D2.0260.99
136_I140_D2.0120.99
200_I205_T2.0050.99
256_S260_S1.9430.99
112_P115_G1.9340.99
70_I73_L1.9180.99
168_K186_D1.8400.99
108_A123_R1.8350.99
252_K255_G1.8080.98
55_G63_Y1.7690.98
142_I202_D1.7580.98
227_N231_G1.7560.98
291_Q295_S1.7400.98
23_F143_A1.7210.98
11_V78_G1.7060.98
14_W93_F1.6850.97
168_K172_R1.6730.97
146_K153_D1.6680.97
57_F70_I1.6440.97
12_V31_I1.6080.97
198_Q208_G1.5850.96
247_G252_K1.5820.96
256_S261_D1.5360.96
251_G257_G1.5120.95
288_S292_S1.5070.95
244_M248_M1.5000.95
295_S298_K1.4910.95
291_Q294_G1.4840.95
110_N177_M1.4780.95
293_T297_S1.4670.94
9_A35_S1.4540.94
137_S200_I1.4540.94
164_Q188_A1.4410.94
121_P225_T1.4380.94
131_K207_T1.4190.93
177_M216_Y1.4150.93
230_Y233_V1.4120.93
74_S78_G1.4080.93
274_Q277_N1.3980.93
249_A252_K1.3940.93
123_R215_N1.3870.93
254_S257_G1.3810.92
103_W209_F1.3640.92
7_Q75_T1.3460.91
18_R21_M1.3410.91
290_P293_T1.3350.91
292_S295_S1.3340.91
47_F57_F1.3320.91
251_G255_G1.3280.91
138_L142_I1.3130.90
106_K125_N1.2870.89
286_Q292_S1.2830.89
223_M229_S1.2790.89
44_D96_T1.2790.89
31_I35_S1.2770.89
41_P140_D1.2730.89
36_R64_D1.2650.89
289_G292_S1.2640.88
119_G178_F1.2640.88
294_G297_S1.2550.88
226_K229_S1.2520.88
286_Q291_Q1.2490.88
278_Q281_Q1.2420.88
167_M213_S1.2370.87
3_F27_N1.2320.87
230_Y242_I1.2300.87
281_Q284_Q1.2300.87
230_Y239_Y1.2200.87
268_G272_A1.2080.86
255_G258_A1.2080.86
30_E88_R1.2030.86
230_Y234_G1.1940.85
47_F89_A1.1890.85
280_N283_Q1.1770.85
275_M279_M1.1740.84
223_M227_N1.1700.84
276_M279_M1.1560.84
115_G176_D1.1530.83
131_K141_K1.1480.83
22_I94_V1.1470.83
103_W162_L1.1370.83
187_I209_F1.1330.82
134_D137_S1.1310.82
281_Q296_G1.1280.82
226_K246_D1.1230.82
107_Q213_S1.1220.82
224_I228_A1.1200.82
276_M280_N1.1190.81
38_I93_F1.1160.81
17_F24_Y1.1140.81
294_G298_K1.1070.81
13_E40_R1.1060.81
9_A80_K1.0980.80
33_K66_E1.0950.80
127_T160_S1.0940.80
46_V56_V1.0930.80
262_M265_M1.0930.80
120_M216_Y1.0880.80
32_K35_S1.0810.79
165_L185_F1.0780.79
198_Q201_S1.0740.79
20_D150_F1.0700.78
11_V74_S1.0670.78
16_E21_M1.0670.78
292_S297_S1.0590.78
239_Y242_I1.0550.77
237_N240_Q1.0480.77
98_E202_D1.0460.77
22_I42_G1.0450.77
37_L57_F1.0400.76
50_N62_D1.0400.76
265_M271_M1.0390.76
48_L53_V1.0390.76
287_S290_P1.0330.76
101_V162_L1.0320.76
174_G212_M1.0280.76
105_T108_A1.0270.76
263_A266_M1.0250.75
254_S272_A1.0200.75
287_S291_Q1.0190.75
243_S249_A1.0180.75
288_S291_Q1.0180.75
172_R194_D1.0140.75
158_I199_L1.0100.74
190_G193_E1.0070.74
258_A262_M1.0060.74
169_W194_D1.0050.74
255_G261_D1.0000.74
269_M272_A0.9990.73
267_M277_N0.9930.73
285_A292_S0.9920.73
44_D58_Q0.9860.73
290_P295_S0.9830.72
285_A291_Q0.9820.72
226_K230_Y0.9690.71
239_Y246_D0.9570.70
267_M275_M0.9520.70
279_M284_Q0.9470.69
168_K185_F0.9410.69
131_K171_T0.9340.68
255_G260_S0.9290.68
272_A276_M0.9290.68
154_I158_I0.9260.68
288_S296_G0.9240.68
293_T298_K0.9200.67
217_P220_V0.9200.67
265_M272_A0.9190.67
154_I189_K0.9180.67
164_Q211_I0.9180.67
272_A277_N0.9150.67
10_N78_G0.9130.67
86_G91_V0.9130.67
118_G220_V0.9080.66
23_F94_V0.9060.66
37_L65_I0.9050.66
13_E88_R0.8980.65
173_E190_G0.8980.65
42_G145_V0.8910.65
47_F70_I0.8880.64
67_S88_R0.8860.64
280_N284_Q0.8790.64
275_M280_N0.8760.63
48_L92_L0.8750.63
103_W124_A0.8740.63
285_A289_G0.8730.63
240_Q244_M0.8710.63
98_E129_N0.8680.63
13_E38_I0.8660.62
69_I87_M0.8650.62
11_V85_S0.8640.62
22_I151_V0.8620.62
40_R43_Q0.8560.62
164_Q184_A0.8560.62
274_Q280_N0.8560.62
125_N242_I0.8480.61
259_A264_G0.8400.60
172_R185_F0.8320.59
10_N28_N0.8310.59
103_W164_Q0.8310.59
192_Q196_D0.8290.59
132_V192_Q0.8260.59
70_I87_M0.8250.59
112_P179_N0.8240.59
288_S293_T0.8240.59
238_R241_Q0.8230.58
189_K192_Q0.8230.58
288_S294_G0.8170.58
223_M231_G0.8170.58
19_D146_K0.8150.58
216_Y232_M0.8120.57
50_N88_R0.8090.57
55_G72_F0.8000.56
165_L198_Q0.7960.56
130_F155_K0.7940.56
281_Q288_S0.7930.56
142_I208_G0.7930.56
22_I99_F0.7910.55
56_V96_T0.7910.55
292_S296_G0.7890.55
94_V139_I0.7870.55
15_E29_R0.7850.55
167_M171_T0.7840.55
67_S76_L0.7810.54
242_I246_D0.7800.54
141_K201_S0.7790.54
261_D264_G0.7780.54
11_V75_T0.7750.54
102_R142_I0.7700.53
265_M269_M0.7680.53
116_M227_N0.7670.53
189_K193_E0.7650.53
62_D68_E0.7640.53
288_S297_S0.7630.53
285_A290_P0.7610.53
11_V38_I0.7580.52
31_I88_R0.7540.52
173_E183_N0.7510.52
23_F191_I0.7500.52
166_L191_I0.7490.51
11_V88_R0.7460.51
101_V155_K0.7440.51
284_Q288_S0.7440.51
101_V128_F0.7360.50
285_A296_G0.7330.50
265_M273_N0.7290.50
105_T109_I0.7250.49
228_A231_G0.7250.49
243_S246_D0.7220.49
48_L139_I0.7200.49
138_L166_L0.7180.48
279_M282_N0.7170.48
4_F72_F0.7140.48
263_A267_M0.7130.48
260_S266_M0.7120.48
21_M148_Q0.7110.48
107_Q125_N0.7100.48
137_S140_D0.7080.47
288_S295_S0.7080.47
55_G86_G0.7060.47
227_N232_M0.7050.47
118_G225_T0.7020.47
98_E141_K0.7010.47
239_Y268_G0.6990.47
155_K158_I0.6910.46
46_V139_I0.6880.46
240_Q248_M0.6880.46
115_G119_G0.6880.46
292_S298_K0.6870.45
106_K271_M0.6870.45
211_I270_N0.6850.45
125_N213_S0.6800.45
252_K272_A0.6800.45
118_G234_G0.6780.45
269_M273_N0.6770.45
293_T296_G0.6760.44
226_K239_Y0.6760.44
66_E206_V0.6720.44
283_Q287_S0.6720.44
278_Q289_G0.6680.44
7_Q27_N0.6630.43
56_V132_V0.6560.43
100_T130_F0.6520.42
90_E143_A0.6490.42
256_S285_A0.6440.41
263_A271_M0.6430.41
287_S295_S0.6390.41
274_Q283_Q0.6380.41
79_F83_F0.6370.41
221_Q225_T0.6350.41
166_L170_I0.6330.40
172_R186_D0.6330.40
19_D153_D0.6310.40
258_A270_N0.6270.40
115_G221_Q0.6260.40
281_Q285_A0.6250.40
100_T132_V0.6250.40
47_F54_E0.6240.40
38_I157_R0.6230.39
227_N234_G0.6230.39
13_E29_R0.6220.39
161_I210_Q0.6220.39
276_M282_N0.6220.39
20_D99_F0.6220.39
105_T124_A0.6210.39
112_P221_Q0.6210.39
194_D197_M0.6210.39
290_P294_G0.6200.39
175_K219_E0.6180.39
6_N27_N0.6160.39
286_Q290_P0.6150.39
189_K293_T0.6140.39
162_L187_I0.6140.39
50_N67_S0.6120.38
30_E103_W0.6110.38
29_R75_T0.6110.38
21_M150_F0.6110.38
257_G261_D0.6110.38
274_Q287_S0.6110.38
103_W210_Q0.6080.38
111_I170_I0.6070.38
158_I204_M0.6070.38
239_Y249_A0.6050.38
211_I222_D0.6050.38
57_F65_I0.6050.38
50_N77_K0.6040.38
35_S79_F0.6030.38
286_Q294_G0.5990.37
278_Q294_G0.5980.37
245_T249_A0.5980.37
220_V228_A0.5980.37
15_E25_K0.5980.37
150_F206_V0.5960.37
270_N280_N0.5940.37
291_Q296_G0.5930.37
12_V35_S0.5890.36
235_D240_Q0.5890.36
36_R86_G0.5880.36
220_V232_M0.5870.36
277_N280_N0.5850.36
53_V218_Q0.5840.36
3_F7_Q0.5840.36
289_G296_G0.5830.36
287_S298_K0.5820.36
11_V62_D0.5810.36
133_Q253_M0.5810.36
43_Q105_T0.5800.36
47_F65_I0.5800.36
277_N285_A0.5790.35
32_K83_F0.5770.35
123_R181_Q0.5760.35
125_N162_L0.5760.35
179_N221_Q0.5750.35
144_G217_P0.5750.35
157_R245_T0.5750.35
32_K91_V0.5750.35
231_G247_G0.5740.35
282_N289_G0.5730.35
18_R170_I0.5700.35
33_K68_E0.5690.35
50_N83_F0.5680.35
289_G293_T0.5680.35
261_D273_N0.5670.34
58_Q63_Y0.5640.34
262_M266_M0.5630.34
120_M170_I0.5610.34
139_I177_M0.5600.34
278_Q285_A0.5590.34
32_K89_A0.5580.34
93_F271_M0.5570.34
13_E32_K0.5560.33
125_N215_N0.5560.33
119_G176_D0.5560.33
4_F243_S0.5550.33
240_Q279_M0.5550.33
58_Q135_Y0.5530.33
280_N287_S0.5530.33
30_E85_S0.5520.33
49_N68_E0.5500.33
215_N221_Q0.5500.33
156_T265_M0.5480.33
219_E225_T0.5470.33
284_Q291_Q0.5470.33
58_Q72_F0.5470.33
73_L90_E0.5470.33
142_I158_I0.5450.33
25_K92_L0.5450.33
187_I194_D0.5450.33
235_D241_Q0.5440.32
227_N239_Y0.5440.32
137_S141_K0.5420.32
189_K281_Q0.5410.32
274_Q278_Q0.5410.32
16_E40_R0.5400.32
284_Q295_S0.5390.32
14_W43_Q0.5370.32
83_F220_V0.5370.32
120_M173_E0.5360.32
7_Q63_Y0.5360.32
206_V281_Q0.5360.32
171_T215_N0.5350.32
18_R95_N0.5330.32
251_G264_G0.5330.32
285_A295_S0.5300.31
251_G261_D0.5300.31
49_N89_A0.5290.31
112_P119_G0.5280.31
56_V246_D0.5260.31
184_A188_A0.5260.31
148_Q189_K0.5250.31
152_E202_D0.5250.31
56_V136_I0.5240.31
186_D189_K0.5240.31
30_E70_I0.5230.31
164_Q191_I0.5220.31
266_M272_A0.5220.31
164_Q210_Q0.5190.30
10_N219_E0.5160.30
199_L206_V0.5150.30
51_G71_P0.5140.30
101_V151_V0.5110.30
161_I202_D0.5100.30
163_D167_M0.5090.30
94_V273_N0.5080.30
121_P220_V0.5080.30
274_Q279_M0.5070.29
270_N276_M0.5070.29
113_A119_G0.5060.29
82_G124_A0.5050.29
3_F29_R0.5040.29
99_F187_I0.5030.29
104_G126_G0.5020.29
3_F11_V0.5010.29
9_A64_D0.5010.29
49_N77_K0.5000.29
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4fvgA 2 0.3375 99.6 0.852 Contact Map
1winA 1 0.4427 99.5 0.856 Contact Map
3bk6A 3 0.5263 99.3 0.874 Contact Map
2rpbA 1 0.3498 99.1 0.882 Contact Map
3h0gL 1 0.0836 95.9 0.94 Contact Map
2lcqA 1 0.4458 89.4 0.953 Contact Map
1twfL 1 0.0867 86.7 0.955 Contact Map
3wwlA 1 0.0805 86.7 0.955 Contact Map
2jrpA 1 0.13 83.7 0.956 Contact Map
4aybP 1 0.0712 81 0.958 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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