GREMLIN Database
YLBJ - Sporulation integral membrane protein YlbJ
UniProt: O34765 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 408 (361)
Sequences: 547 (481)
Seq/√Len: 25.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
49_L53_I9.3081.00
161_A339_F6.6821.00
108_R319_D6.0151.00
142_F296_V5.7191.00
298_F333_G5.1331.00
40_W225_G4.7641.00
44_V228_I4.7011.00
92_G126_N4.1981.00
88_V103_L3.9721.00
115_R321_R3.7471.00
133_I151_L3.3771.00
81_V85_G3.2711.00
109_Q317_E3.0091.00
325_F329_R2.9851.00
302_F308_Q2.7900.99
115_R319_D2.7220.99
308_Q322_F2.7190.99
82_P117_E2.7140.99
22_V29_S2.6620.99
165_T335_Y2.6150.99
128_S155_H2.5450.99
108_R118_A2.5450.99
40_W45_F2.4160.98
105_A318_T2.2960.98
157_L339_F2.2720.98
60_G209_I2.2520.98
108_R115_R2.2230.97
138_A148_G2.1460.97
126_N275_I2.0600.96
157_L161_A2.0600.96
93_M159_N2.0410.96
68_G83_G2.0400.96
356_Q359_F2.0380.96
122_A315_L2.0320.95
341_M345_K1.9940.95
97_N325_F1.9470.94
159_N329_R1.9440.94
27_Q31_E1.8770.93
218_V222_L1.8200.92
192_L197_T1.8190.92
40_W226_G1.7910.91
126_N329_R1.7330.90
97_N301_G1.7290.90
107_L113_I1.7240.90
161_A335_Y1.7080.89
301_G333_G1.7030.89
71_L90_A1.6800.88
36_G232_S1.6570.88
40_W95_S1.6490.87
374_G378_L1.6360.87
368_S378_L1.6190.86
158_G336_A1.6130.86
85_G121_L1.5810.85
99_A129_N1.5800.85
29_S32_A1.5650.84
47_S128_S1.5650.84
371_F377_L1.5490.84
129_N329_R1.5480.84
67_V123_S1.5390.83
132_F276_T1.5360.83
254_A258_F1.5340.83
271_G306_S1.5020.82
86_G216_S1.5010.82
360_K375_W1.4970.82
39_M275_I1.4860.81
160_L295_I1.4850.81
22_V151_L1.4710.80
141_F279_S1.4640.80
150_L343_L1.4570.80
49_L228_I1.4470.79
65_R198_A1.4430.79
156_Y309_A1.4410.79
350_A353_D1.4360.79
7_N22_V1.4310.79
97_N126_N1.4140.78
49_L301_G1.3930.77
303_S326_F1.3840.76
137_V198_A1.3690.75
327_I331_L1.3660.75
119_E311_V1.3500.74
260_L295_I1.3410.74
375_W380_Q1.3350.73
251_T375_W1.3250.73
114_S117_E1.3220.73
378_L384_A1.3140.72
294_I337_A1.3010.72
108_R318_T1.2980.71
93_M127_S1.2930.71
74_F344_W1.2910.71
151_L297_S1.2910.71
371_F379_V1.2870.71
295_I305_F1.2850.71
299_I332_Q1.2830.70
39_M126_N1.2790.70
171_R268_L1.2560.69
158_G301_G1.2480.68
298_F337_A1.2450.68
33_S40_W1.2390.68
58_L207_G1.2360.67
372_I379_V1.2330.67
255_L268_L1.2250.67
275_I283_S1.2100.66
94_A302_F1.2080.66
33_S36_G1.1770.64
293_A340_V1.1760.64
97_N127_S1.1750.63
247_L257_L1.1610.63
246_V249_V1.1570.62
71_L210_L1.1560.62
357_Y360_K1.1510.62
246_V256_T1.1490.62
72_E76_R1.1450.61
87_F276_T1.1220.60
157_L303_S1.1200.60
151_L333_G1.1180.60
133_I155_H1.1130.59
106_R110_E1.1110.59
335_Y339_F1.1100.59
352_H377_L1.1040.59
375_W378_L1.1020.58
379_V384_A1.0990.58
23_I347_L1.0850.57
268_L272_M1.0840.57
372_I378_L1.0840.57
330_L334_V1.0830.57
376_N379_V1.0790.57
80_R299_I1.0780.57
33_S233_V1.0700.56
77_P167_R1.0690.56
293_A344_W1.0680.56
47_S127_S1.0630.56
155_H332_Q1.0480.55
280_K284_E1.0470.54
211_G225_G1.0460.54
131_L233_V1.0350.54
187_S190_D1.0320.53
79_F83_G1.0290.53
336_A339_F1.0240.53
158_G305_F1.0200.53
32_A223_M1.0180.52
245_D249_V1.0180.52
158_G332_Q1.0140.52
77_P142_F1.0140.52
128_S238_L1.0120.52
279_S296_V1.0110.52
158_G335_Y1.0080.52
216_S300_L1.0050.51
105_A315_L1.0050.51
77_P119_E1.0040.51
251_T268_L0.9990.51
358_V362_L0.9970.51
378_L382_G0.9960.51
52_F217_S0.9950.51
133_I156_Y0.9910.50
372_I375_W0.9910.50
249_V253_G0.9910.50
36_G227_F0.9900.50
368_S377_L0.9870.50
44_V59_I0.9830.50
129_N301_G0.9810.50
19_T250_F0.9770.49
26_P36_G0.9760.49
158_G340_V0.9730.49
360_K381_I0.9720.49
301_G336_A0.9700.49
372_I381_I0.9690.49
124_F167_R0.9690.49
283_S320_I0.9620.48
95_S276_T0.9620.48
85_G92_G0.9590.48
120_R163_G0.9580.48
201_A234_F0.9570.48
300_L308_Q0.9540.48
369_T373_N0.9520.48
362_L372_I0.9490.47
144_N292_K0.9490.47
154_A303_S0.9400.47
126_N325_F0.9390.47
91_M163_G0.9390.47
227_F307_V0.9380.47
374_G384_A0.9360.46
40_W44_V0.9340.46
52_F125_T0.9330.46
370_A384_A0.9310.46
102_K276_T0.9290.46
213_A269_L0.9260.46
374_G380_Q0.9250.46
337_A341_M0.9250.46
59_I222_L0.9240.46
17_F268_L0.9240.46
88_V104_T0.9170.45
371_F374_G0.9160.45
134_F138_A0.9140.45
374_G377_L0.9110.45
357_Y362_L0.9100.45
369_T378_L0.9070.44
97_N307_V0.9030.44
30_F314_I0.9020.44
40_W211_G0.9020.44
148_G227_F0.9010.44
127_S159_N0.9010.44
136_A141_F0.9000.44
311_V329_R0.8980.44
215_T219_Q0.8980.44
120_R227_F0.8930.43
85_G314_I0.8930.43
104_T318_T0.8910.43
75_M79_F0.8910.43
125_T207_G0.8860.43
369_T376_N0.8860.43
197_T250_F0.8840.43
104_T125_T0.8830.43
373_N376_N0.8800.42
205_P329_R0.8780.42
373_N380_Q0.8760.42
359_F362_L0.8750.42
121_L271_G0.8740.42
191_A195_L0.8740.42
373_N377_L0.8700.42
40_W117_E0.8680.42
377_L380_Q0.8670.41
350_A354_P0.8670.41
143_Q146_S0.8650.41
119_E125_T0.8610.41
358_V361_S0.8570.41
360_K371_F0.8550.41
78_I306_S0.8540.41
252_K362_L0.8530.40
190_D194_A0.8520.40
150_L164_L0.8510.40
33_S225_G0.8510.40
71_L144_N0.8500.40
203_K209_I0.8480.40
80_R171_R0.8480.40
56_E125_T0.8480.40
131_L224_V0.8470.40
269_L342_L0.8470.40
208_K212_D0.8450.40
45_F218_V0.8430.40
65_R112_Q0.8410.40
252_K358_V0.8400.40
297_S336_A0.8380.39
102_K220_T0.8350.39
43_V136_A0.8340.39
147_L293_A0.8330.39
124_F163_G0.8320.39
297_S340_V0.8310.39
125_T329_R0.8290.39
88_V329_R0.8270.39
351_W362_L0.8270.39
259_Q288_S0.8270.39
77_P87_F0.8260.39
229_I270_S0.8230.38
40_W87_F0.8230.38
151_L300_L0.8160.38
127_S235_N0.8140.38
211_G227_F0.8130.38
70_L145_A0.8060.37
138_A169_Y0.8050.37
63_I78_I0.8050.37
95_S329_R0.8040.37
97_N129_N0.8030.37
376_N381_I0.8020.37
141_F322_F0.7980.37
52_F155_H0.7980.37
247_L354_P0.7950.36
373_N378_L0.7950.36
357_Y372_I0.7940.36
369_T372_I0.7930.36
91_M103_L0.7920.36
351_W358_V0.7910.36
339_F343_L0.7900.36
19_T214_V0.7900.36
154_A340_V0.7830.36
198_A202_E0.7820.36
208_K221_L0.7800.35
234_F256_T0.7780.35
71_L344_W0.7770.35
206_L331_L0.7750.35
368_S381_I0.7740.35
127_S300_L0.7740.35
196_H200_L0.7730.35
206_L210_L0.7710.35
86_G127_S0.7680.35
71_L332_Q0.7630.34
305_F377_L0.7620.34
145_A229_I0.7590.34
377_L384_A0.7590.34
129_N302_F0.7530.34
282_V306_S0.7500.33
100_G276_T0.7490.33
64_V156_Y0.7460.33
258_F359_F0.7440.33
369_T379_V0.7440.33
334_V338_V0.7430.33
136_A232_S0.7430.33
115_R119_E0.7420.33
97_N214_V0.7400.33
207_G226_G0.7390.33
47_S150_L0.7380.33
57_L147_L0.7370.33
192_L247_L0.7370.33
375_W379_V0.7370.33
120_R297_S0.7350.33
106_R109_Q0.7350.33
97_N375_W0.7350.33
133_I162_V0.7340.32
127_S329_R0.7270.32
11_I14_F0.7260.32
126_N307_V0.7240.32
44_V275_I0.7230.32
91_M147_L0.7220.32
99_A221_L0.7190.31
52_F77_P0.7160.31
134_F137_V0.7150.31
352_H369_T0.7140.31
32_A135_G0.7110.31
18_L260_L0.7090.31
362_L379_V0.7090.31
271_G332_Q0.7090.31
50_P117_E0.7080.31
44_V235_N0.7050.31
273_F279_S0.7050.31
16_L281_L0.7050.31
138_A156_Y0.7020.30
86_G344_W0.7010.30
138_A151_L0.7000.30
175_Q268_L0.6980.30
136_A140_G0.6970.30
301_G328_A0.6950.30
66_F87_F0.6920.30
368_S371_F0.6910.30
359_F375_W0.6910.30
7_N100_G0.6910.30
104_T118_A0.6880.30
245_D248_S0.6850.29
230_L322_F0.6840.29
204_R212_D0.6830.29
306_S332_Q0.6830.29
356_Q370_A0.6820.29
79_F124_F0.6780.29
15_F214_V0.6780.29
99_A325_F0.6750.29
25_H28_A0.6740.29
56_E211_G0.6730.29
371_F380_Q0.6640.28
88_V122_A0.6640.28
305_F337_A0.6630.28
164_L351_W0.6620.28
94_A102_K0.6610.28
128_S133_I0.6570.28
11_I22_V0.6550.28
26_P33_S0.6510.27
85_G117_E0.6510.27
49_L275_I0.6500.27
370_A376_N0.6490.27
81_V279_S0.6480.27
245_D360_K0.6460.27
190_D193_H0.6440.27
21_T237_L0.6440.27
353_D360_K0.6430.27
97_N163_G0.6430.27
251_T357_Y0.6430.27
116_V170_G0.6410.27
120_R148_G0.6410.27
356_Q379_V0.6400.27
36_G225_G0.6400.27
77_P124_F0.6380.27
360_K370_A0.6370.27
17_F21_T0.6350.26
13_S380_Q0.6340.26
94_A301_G0.6330.26
354_P377_L0.6330.26
76_R83_G0.6330.26
250_F256_T0.6330.26
89_L160_L0.6330.26
272_M305_F0.6300.26
120_R271_G0.6290.26
52_F75_M0.6290.26
28_A210_L0.6290.26
374_G382_G0.6280.26
213_A306_S0.6270.26
43_V97_N0.6270.26
142_F255_L0.6270.26
75_M86_G0.6250.26
10_L70_L0.6230.26
368_S372_I0.6220.26
148_G297_S0.6200.26
277_L344_W0.6190.26
245_D368_S0.6170.25
245_D370_A0.6170.25
377_L381_I0.6160.25
222_L342_L0.6160.25
170_G238_L0.6140.25
372_I383_P0.6140.25
59_I342_L0.6140.25
247_L258_F0.6130.25
294_I334_V0.6130.25
174_E272_M0.6120.25
249_V258_F0.6110.25
129_N308_Q0.6100.25
253_G257_L0.6100.25
284_E338_V0.6100.25
91_M125_T0.6090.25
29_S292_K0.6090.25
141_F300_L0.6080.25
88_V280_K0.6080.25
246_V251_T0.6050.25
254_A356_Q0.6050.25
111_N245_D0.6040.25
164_L335_Y0.6040.25
154_A296_V0.6030.25
162_V222_L0.6010.25
92_G121_L0.6010.25
15_F192_L0.6000.25
220_T228_I0.5990.24
99_A127_S0.5990.24
64_V121_L0.5980.24
155_H340_V0.5980.24
78_I334_V0.5970.24
119_E321_R0.5970.24
8_T11_I0.5960.24
88_V159_N0.5960.24
14_F345_K0.5940.24
360_K372_I0.5930.24
20_A362_L0.5920.24
87_F147_L0.5920.24
100_G129_N0.5910.24
187_S193_H0.5910.24
47_S294_I0.5880.24
129_N159_N0.5880.24
158_G217_S0.5870.24
257_L342_L0.5870.24
75_M83_G0.5860.24
373_N383_P0.5850.24
14_F268_L0.5840.24
265_D269_L0.5840.24
92_G279_S0.5820.24
135_G218_V0.5820.24
95_S314_I0.5820.24
362_L381_I0.5800.23
137_V296_V0.5800.23
217_S226_G0.5790.23
81_V128_S0.5790.23
32_A36_G0.5780.23
187_S371_F0.5770.23
89_L93_M0.5770.23
173_E224_V0.5760.23
148_G211_G0.5750.23
82_P91_M0.5740.23
40_W50_P0.5730.23
351_W359_F0.5710.23
127_S325_F0.5700.23
192_L336_A0.5690.23
124_F315_L0.5690.23
210_L230_L0.5650.23
30_F210_L0.5640.23
354_P369_T0.5640.23
129_N141_F0.5630.23
40_W221_L0.5630.23
254_A288_S0.5610.22
105_A206_L0.5610.22
303_S320_I0.5590.22
52_F95_S0.5570.22
9_L13_S0.5570.22
159_N308_Q0.5560.22
322_F325_F0.5550.22
131_L226_G0.5550.22
44_V227_F0.5540.22
225_G307_V0.5530.22
155_H163_G0.5530.22
32_A236_R0.5530.22
249_V252_K0.5520.22
53_I271_G0.5520.22
71_L303_S0.5510.22
121_L167_R0.5510.22
356_Q360_K0.5500.22
248_S253_G0.5500.22
356_Q373_N0.5480.22
15_F29_S0.5480.22
211_G222_L0.5460.22
21_T283_S0.5460.22
300_L333_G0.5450.22
126_N294_I0.5440.22
121_L217_S0.5430.22
370_A383_P0.5430.22
372_I384_A0.5430.22
126_N129_N0.5420.22
352_H362_L0.5410.21
37_L41_W0.5400.21
104_T138_A0.5390.21
45_F129_N0.5380.21
159_N325_F0.5370.21
63_I79_F0.5370.21
352_H359_F0.5370.21
128_S340_V0.5360.21
362_L374_G0.5360.21
83_G86_G0.5340.21
373_N381_I0.5340.21
111_N358_V0.5320.21
24_S188_V0.5320.21
133_I302_F0.5320.21
56_E75_M0.5320.21
125_T321_R0.5320.21
63_I222_L0.5310.21
289_L292_K0.5300.21
68_G76_R0.5300.21
298_F301_G0.5300.21
111_N176_H0.5280.21
303_S379_V0.5270.21
231_F309_A0.5260.21
303_S325_F0.5250.21
198_A302_F0.5250.21
45_F62_G0.5240.21
193_H197_T0.5240.21
97_N228_I0.5220.21
245_D256_T0.5220.21
227_F271_G0.5190.20
114_S214_V0.5180.20
24_S266_I0.5170.20
108_R114_S0.5160.20
370_A373_N0.5160.20
227_F298_F0.5140.20
150_L374_G0.5140.20
62_G68_G0.5110.20
198_A204_R0.5100.20
41_W104_T0.5090.20
354_P357_Y0.5080.20
350_A361_S0.5070.20
61_F141_F0.5060.20
250_F353_D0.5060.20
128_S300_L0.5050.20
372_I382_G0.5050.20
247_L252_K0.5050.20
126_N228_I0.5050.20
97_N236_R0.5030.20
53_I103_L0.5030.20
43_V165_T0.5020.20
23_I69_V0.5010.20
359_F377_L0.5010.20
131_L220_T0.5010.20
271_G299_I0.5000.20
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4pd6A 3 0.7549 99 0.887 Contact Map
2cfqA 1 0.8873 13.8 0.974 Contact Map
2ariA 1 0.0686 11.2 0.975 Contact Map
2kv5A 1 0.0809 5.4 0.978 Contact Map
3wdoA 1 0.4755 4.5 0.979 Contact Map
2kncA 1 0.1103 3.9 0.98 Contact Map
4pypA 1 0.3824 3.7 0.98 Contact Map
2l8sA 1 0.1029 3.5 0.98 Contact Map
4he8J 1 0.3603 3.3 0.981 Contact Map
2mc7A 1 0.0735 3.3 0.981 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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