YTNP - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YTNP - Probable quorum-quenching lactonase YtnP

UniProt:	O34760	Sequences: METMKIGNITLTWLDGGVTHMDGGAMFGVVPKPLWSKKYPVNEKNQIELRTDPILIQKDGLNIIIDAGIGYGKLTDKQKRNYGVTQESNVKPSLAALGLTVADIDVIAMTHLHFDHACGLTEYEGERLVSVFPNAVIYTSAVEWDEMRHPNIRSKNTYWKENWEAVAGQVKTFEDTLTITEGITMHHTGGHSDGHSVLICEDAGETAVHMADLMPTHAHRNPLWVLAYDDYPMTSIPQKQKWQAFAAEKDAWFIFYHDAEYRALQWEEDGSIKKSVKRMKR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	281 (249)
Sequences:	3334 (2414)
Seq/√Len:	153.0

BACSU - YTNP
HALSA - Q9HQ42
SULSO - Q97Y13 Q97YH8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
188_T	197_V	6.260	1.00
57_Q	62_N	4.476	1.00
141_A	145_D	4.408	1.00
141_A	174_E	4.401	1.00
10_T	57_Q	3.866	1.00
136_V	171_K	3.576	1.00
106_V	138_Y	3.222	1.00
61_L	106_V	2.905	1.00
8_N	203_A	2.897	1.00
65_I	110_T	2.896	1.00
102_A	133_P	2.696	1.00
140_S	196_S	2.651	1.00
100_T	103_D	2.546	1.00
62_N	99_L	2.530	1.00
178_T	181_E	2.529	1.00
62_N	104_I	2.483	1.00
231_Y	234_T	2.452	1.00
199_I	206_T	2.365	1.00
57_Q	99_L	2.297	1.00
245_F	249_K	2.273	1.00
95_A	100_T	2.251	1.00
61_L	105_D	2.219	1.00
178_T	182_G	2.216	1.00
188_T	195_H	2.208	1.00
183_I	200_C	2.112	1.00
189_G	238_Q	1.998	1.00
110_T	198_L	1.947	1.00
195_H	211_A	1.939	1.00
244_A	268_E	1.914	1.00
186_H	199_I	1.905	1.00
55_L	99_L	1.879	1.00
9_I	58_K	1.871	1.00
65_I	198_L	1.827	1.00
109_M	120_L	1.796	1.00
12_T	57_Q	1.794	1.00
184_T	201_E	1.792	1.00
14_L	55_L	1.785	1.00
64_I	104_I	1.777	1.00
56_I	65_I	1.725	1.00
185_M	198_L	1.720	1.00
108_A	198_L	1.716	1.00
213_L	242_W	1.714	1.00
201_E	206_T	1.696	1.00
199_I	208_V	1.695	1.00
234_T	237_P	1.660	1.00
246_A	251_A	1.587	1.00
248_E	268_E	1.569	1.00
55_L	64_I	1.538	1.00
159_W	166_V	1.536	1.00
120_L	137_I	1.534	1.00
173_F	196_S	1.497	1.00
8_N	202_D	1.489	1.00
199_I	245_F	1.489	1.00
99_L	103_D	1.485	1.00
106_V	136_V	1.453	1.00
63_I	183_I	1.440	1.00
244_A	248_E	1.431	1.00
240_Q	244_A	1.404	1.00
237_P	241_K	1.394	1.00
184_T	199_I	1.385	1.00
94_L	99_L	1.380	1.00
11_L	207_A	1.376	1.00
20_H	48_E	1.374	1.00
112_L	139_T	1.365	1.00
62_N	105_D	1.363	1.00
160_K	164_E	1.344	1.00
102_A	134_N	1.330	1.00
202_D	205_E	1.317	1.00
107_I	137_I	1.310	1.00
14_L	93_S	1.306	1.00
35_W	39_Y	1.290	1.00
144_W	172_T	1.261	1.00
210_M	253_F	1.227	1.00
95_A	101_V	1.225	1.00
206_T	251_A	1.219	1.00
201_E	204_G	1.213	1.00
186_H	208_V	1.212	1.00
145_D	149_H	1.199	1.00
246_A	253_F	1.195	1.00
67_A	120_L	1.194	1.00
91_K	131_V	1.193	1.00
31_P	34_L	1.177	1.00
65_I	108_A	1.151	1.00
140_S	175_D	1.142	1.00
252_W	265_Q	1.138	1.00
146_E	193_D	1.137	1.00
189_G	234_T	1.136	1.00
185_M	196_S	1.131	1.00
55_L	104_I	1.128	1.00
245_F	251_A	1.123	1.00
62_N	103_D	1.118	1.00
63_I	106_V	1.112	0.99
65_I	209_H	1.109	0.99
186_H	197_V	1.107	0.99
225_V	236_I	1.105	0.99
209_H	254_I	1.099	0.99
10_T	62_N	1.095	0.99
54_I	254_I	1.081	0.99
144_W	148_R	1.079	0.99
205_E	252_W	1.072	0.99
162_N	165_A	1.071	0.99
55_L	62_N	1.070	0.99
197_V	208_V	1.065	0.99
139_T	170_V	1.053	0.99
237_P	240_Q	1.039	0.99
89_N	92_P	1.038	0.99
143_E	147_M	1.038	0.99
161_E	164_E	1.033	0.99
62_N	94_L	1.029	0.99
110_T	211_A	1.025	0.99
54_I	209_H	1.021	0.99
58_K	61_L	1.020	0.99
206_T	249_K	1.014	0.99
267_E	271_S	1.011	0.99
138_Y	173_F	1.007	0.99
252_W	263_A	0.996	0.99
18_V	48_E	0.995	0.99
92_P	95_A	0.989	0.99
186_H	245_F	0.988	0.99
120_L	166_V	0.986	0.99
138_Y	171_K	0.982	0.99
32_K	36_S	0.981	0.99
175_D	187_H	0.978	0.99
208_V	246_A	0.977	0.99
158_Y	165_A	0.973	0.99
112_L	117_A	0.967	0.99
141_A	172_T	0.963	0.99
13_W	52_D	0.954	0.98
241_K	245_F	0.949	0.98
112_L	147_M	0.943	0.98
208_V	251_A	0.943	0.98
119_G	131_V	0.933	0.98
197_V	242_W	0.930	0.98
143_E	192_S	0.929	0.98
229_D	239_K	0.928	0.98
108_A	183_I	0.925	0.98
158_Y	161_E	0.925	0.98
109_M	117_A	0.919	0.98
91_K	101_V	0.913	0.98
188_T	238_Q	0.909	0.98
34_L	37_K	0.909	0.98
17_G	68_G	0.907	0.98
23_G	27_F	0.904	0.98
12_T	97_L	0.900	0.98
199_I	251_A	0.896	0.98
145_D	148_R	0.895	0.98
159_W	162_N	0.895	0.98
233_M	236_I	0.892	0.98
58_K	63_I	0.888	0.97
197_V	213_L	0.877	0.97
13_W	54_I	0.875	0.97
9_I	202_D	0.869	0.97
243_Q	266_W	0.864	0.97
236_I	240_Q	0.861	0.97
175_D	196_S	0.858	0.97
210_M	255_F	0.851	0.97
234_T	238_Q	0.851	0.97
173_F	185_M	0.850	0.97
130_S	133_P	0.848	0.97
176_T	184_T	0.839	0.96
132_F	135_A	0.839	0.96
9_I	182_G	0.833	0.96
33_P	36_S	0.833	0.96
31_P	35_W	0.830	0.96
174_E	177_L	0.820	0.96
130_S	169_Q	0.819	0.96
36_S	39_Y	0.818	0.96
159_W	163_W	0.817	0.96
235_S	239_K	0.816	0.96
223_L	240_Q	0.815	0.96
11_L	254_I	0.812	0.96
16_G	88_S	0.811	0.96
14_L	97_L	0.811	0.96
176_T	187_H	0.809	0.96
14_L	99_L	0.803	0.95
70_G	119_G	0.800	0.95
209_H	256_Y	0.800	0.95
138_Y	177_L	0.797	0.95
162_N	166_V	0.797	0.95
244_A	247_A	0.792	0.95
95_A	270_G	0.789	0.95
142_V	175_D	0.789	0.95
13_W	254_I	0.789	0.95
30_V	35_W	0.787	0.95
64_I	107_I	0.785	0.95
32_K	35_W	0.780	0.95
254_I	263_A	0.779	0.95
94_L	104_I	0.778	0.95
223_L	236_I	0.777	0.95
144_W	170_V	0.774	0.94
193_D	231_Y	0.768	0.94
36_S	40_P	0.767	0.94
268_E	271_S	0.762	0.94
88_S	96_A	0.758	0.94
68_G	109_M	0.755	0.94
26_M	226_L	0.752	0.94
104_I	135_A	0.750	0.93
205_E	265_Q	0.748	0.93
178_T	201_E	0.742	0.93
64_I	94_L	0.741	0.93
158_Y	162_N	0.740	0.93
109_M	137_I	0.738	0.93
104_I	136_V	0.737	0.93
140_S	173_F	0.735	0.93
16_G	70_G	0.725	0.92
250_D	265_Q	0.725	0.92
247_A	266_W	0.725	0.92
53_P	90_V	0.724	0.92
56_I	183_I	0.721	0.92
215_P	219_H	0.719	0.92
106_V	180_T	0.717	0.92
37_K	40_P	0.710	0.91
21_M	49_L	0.709	0.91
210_M	213_L	0.703	0.91
101_V	131_V	0.700	0.91
69_I	82_Y	0.699	0.91
245_F	250_D	0.696	0.91
142_V	145_D	0.694	0.91
28_G	31_P	0.691	0.90
243_Q	247_A	0.690	0.90
22_D	45_N	0.689	0.90
54_I	207_A	0.689	0.90
215_P	226_L	0.687	0.90
153_R	157_T	0.687	0.90
158_Y	166_V	0.684	0.90
221_N	224_W	0.680	0.90
217_H	258_D	0.679	0.90
50_R	215_P	0.677	0.89
51_T	87_E	0.677	0.89
108_A	179_I	0.676	0.89
15_D	89_N	0.675	0.89
63_I	108_A	0.675	0.89
65_I	211_A	0.674	0.89
64_I	67_A	0.672	0.89
214_M	258_D	0.672	0.89
161_E	165_A	0.672	0.89
142_V	174_E	0.671	0.89
140_S	143_E	0.671	0.89
70_G	229_D	0.667	0.89
143_E	195_H	0.665	0.89
15_D	93_S	0.663	0.88
54_I	256_Y	0.661	0.88
55_L	97_L	0.660	0.88
178_T	184_T	0.659	0.88
22_D	25_A	0.659	0.88
207_A	254_I	0.658	0.88
142_V	189_G	0.657	0.88
67_A	117_A	0.657	0.88
93_S	96_A	0.657	0.88
116_H	257_H	0.653	0.88
199_I	249_K	0.650	0.87
209_H	255_F	0.649	0.87
130_S	137_I	0.644	0.87
56_I	63_I	0.637	0.86
22_D	27_F	0.637	0.86
10_T	99_L	0.635	0.86
200_C	209_H	0.635	0.86
9_I	200_C	0.635	0.86
208_V	242_W	0.635	0.86
137_I	166_V	0.633	0.86
190_G	212_D	0.633	0.86
163_W	166_V	0.632	0.86
11_L	54_I	0.631	0.86
220_R	258_D	0.631	0.86
139_T	172_T	0.629	0.86
131_V	137_I	0.629	0.86
57_Q	104_I	0.628	0.86
117_A	120_L	0.627	0.86
24_G	35_W	0.626	0.85
177_L	185_M	0.626	0.85
174_E	187_H	0.625	0.85
53_P	256_Y	0.623	0.85
15_D	52_D	0.622	0.85
120_L	130_S	0.621	0.85
27_F	35_W	0.618	0.85
213_L	238_Q	0.617	0.85
30_V	34_L	0.615	0.84
29_V	34_L	0.614	0.84
192_S	229_D	0.610	0.84
171_K	177_L	0.607	0.84
63_I	180_T	0.605	0.83
226_L	229_D	0.600	0.83
130_S	168_G	0.599	0.83
233_M	237_P	0.599	0.83
239_K	243_Q	0.598	0.83
242_W	246_A	0.598	0.83
8_N	36_S	0.595	0.82
202_D	206_T	0.592	0.82
183_I	198_L	0.592	0.82
57_Q	103_D	0.592	0.82
66_D	257_H	0.591	0.82
33_P	37_K	0.588	0.82
253_F	266_W	0.585	0.81
154_S	157_T	0.583	0.81
151_N	154_S	0.581	0.81
89_N	96_A	0.581	0.81
137_I	172_T	0.581	0.81
71_Y	92_P	0.581	0.81
101_V	135_A	0.581	0.81
167_A	170_V	0.577	0.80
115_D	257_H	0.573	0.80
82_Y	114_F	0.568	0.79
124_E	271_S	0.566	0.79
94_L	97_L	0.563	0.79
38_K	41_V	0.562	0.79
160_K	163_W	0.562	0.79
211_A	256_Y	0.560	0.78
54_I	215_P	0.560	0.78
136_V	169_Q	0.557	0.78
56_I	205_E	0.554	0.78
176_T	186_H	0.553	0.78
36_S	41_V	0.551	0.77
56_I	133_P	0.548	0.77
86_Q	92_P	0.548	0.77
146_E	192_S	0.547	0.77
68_G	194_G	0.544	0.76
9_I	56_I	0.542	0.76
71_Y	89_N	0.541	0.76
220_R	255_F	0.540	0.76
47_I	216_T	0.539	0.76
107_I	132_F	0.538	0.76
214_M	255_F	0.538	0.76
224_W	228_Y	0.538	0.76
225_V	233_M	0.538	0.76
58_K	202_D	0.537	0.76
210_M	256_Y	0.535	0.75
116_H	191_H	0.535	0.75
144_W	167_A	0.534	0.75
54_I	219_H	0.534	0.75
54_I	255_F	0.533	0.75
59_D	141_A	0.533	0.75
21_M	228_Y	0.532	0.75
33_P	184_T	0.532	0.75
58_K	182_G	0.531	0.75
29_V	32_K	0.530	0.75
71_Y	123_Y	0.530	0.75
69_I	84_V	0.528	0.74
117_A	158_Y	0.527	0.74
93_S	97_L	0.524	0.74
119_G	239_K	0.524	0.74
56_I	180_T	0.522	0.74
42_N	250_D	0.522	0.74
134_N	207_A	0.521	0.73
64_I	90_V	0.521	0.73
197_V	209_H	0.520	0.73
114_F	157_T	0.517	0.73
23_G	45_N	0.517	0.73
58_K	180_T	0.516	0.73
13_W	16_G	0.516	0.73
64_I	100_T	0.515	0.73
138_Y	185_M	0.514	0.72
182_G	201_E	0.514	0.72
214_M	243_Q	0.513	0.72
26_M	32_K	0.513	0.72
9_I	183_I	0.512	0.72
54_I	65_I	0.512	0.72
42_N	45_N	0.511	0.72
222_P	239_K	0.510	0.72
220_R	243_Q	0.510	0.72
11_L	56_I	0.509	0.72
112_L	143_E	0.509	0.72
11_L	200_C	0.508	0.72
130_S	165_A	0.507	0.71
108_A	196_S	0.506	0.71
92_P	96_A	0.505	0.71
96_A	149_H	0.505	0.71
12_T	99_L	0.504	0.71
140_S	187_H	0.504	0.71
238_Q	242_W	0.504	0.71
107_I	120_L	0.504	0.71
27_F	30_V	0.503	0.71
186_H	241_K	0.502	0.71
110_T	219_H	0.501	0.70
215_P	256_Y	0.500	0.70

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4le6A	4	0.8327	100	0.355	Contact Map
4zo2A	2	0.9537	100	0.373	Contact Map
1p9eA	3	0.9502	100	0.375	Contact Map
3eshA	5	0.9786	100	0.429	Contact Map
3aj3A	2	0.879	100	0.471	Contact Map
2r2dA	5	0.9146	100	0.479	Contact Map
3dhaA	1	0.8683	100	0.503	Contact Map
1ztcA	4	0.6975	100	0.591	Contact Map
4d1tA	1	0.7829	100	0.619	Contact Map
4eybA	2	0.8007	100	0.626	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.009 seconds.