GREMLIN Database
TAGO - Probable undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase
UniProt: O34753 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 358 (296)
Sequences: 6732 (4412)
Seq/√Len: 256.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
275_D286_F4.1571.00
175_T305_S4.0851.00
262_I271_I4.0591.00
167_G298_Y3.9671.00
177_A193_L3.4981.00
192_S229_L3.3481.00
100_S103_V3.3241.00
251_G304_F3.0681.00
86_I111_V2.8001.00
170_V196_I2.7621.00
58_I214_M2.4631.00
148_I227_S2.4291.00
84_A221_F2.4001.00
59_F88_I2.3551.00
20_V61_G2.3541.00
93_L97_Y2.3201.00
276_K285_A2.3021.00
174_S196_I2.2791.00
20_V201_G2.2041.00
289_S292_M2.1371.00
38_D41_S2.1061.00
59_F85_F2.1031.00
166_A199_T1.9681.00
90_L107_I1.9531.00
61_G65_G1.9501.00
83_G224_Y1.9461.00
28_K32_I1.9321.00
63_V85_F1.9241.00
166_A203_L1.9181.00
266_L271_I1.8841.00
195_V225_S1.8611.00
37_V40_P1.8551.00
155_I169_S1.8491.00
62_V195_V1.8431.00
191_L225_S1.8391.00
115_I228_I1.8021.00
169_S173_L1.7981.00
195_V222_L1.7511.00
9_I193_L1.7201.00
109_L145_V1.7201.00
24_T57_A1.6761.00
157_L257_T1.6561.00
139_M142_P1.6401.00
25_P29_R1.6351.00
41_S44_K1.6351.00
104_K108_Q1.6231.00
177_A192_S1.6131.00
170_V200_L1.5981.00
113_I145_V1.5801.00
19_T61_G1.5801.00
43_R46_H1.5771.00
173_L195_V1.5681.00
168_L301_G1.5681.00
180_A233_G1.5621.00
17_L204_F1.5531.00
12_A194_V1.5461.00
92_I96_K1.5391.00
207_F295_L1.5211.00
15_V69_S1.4901.00
104_K220_L1.4871.00
27_V57_A1.4851.00
58_I198_S1.4781.00
30_I33_K1.4701.00
21_L204_F1.4691.00
288_L296_V1.4661.00
105_F108_Q1.4531.00
265_I271_I1.4471.00
109_L149_V1.4441.00
166_A170_V1.4371.00
181_L189_L1.4211.00
175_T249_I1.4181.00
172_G226_I1.4091.00
144_T231_L1.4011.00
150_G261_I1.3811.00
260_A263_R1.3781.00
138_W142_P1.3731.00
162_D209_P1.3711.00
171_I298_Y1.3481.00
37_V41_S1.3451.00
173_L196_I1.3251.00
89_V93_L1.3111.00
169_S222_L1.3061.00
172_G301_G1.2951.00
59_F221_F1.2841.00
36_A41_S1.2711.00
173_L226_I1.2681.00
292_M296_V1.2571.00
29_R33_K1.2561.00
24_T212_I1.2531.00
46_H213_F1.2521.00
156_N216_D1.2361.00
112_A145_V1.2331.00
171_I305_S1.2331.00
199_T222_L1.2281.00
208_H291_R1.2091.00
109_L113_I1.2031.00
295_L299_L1.1981.00
279_I283_L1.1961.00
113_I117_S1.1881.00
65_G194_V1.1861.00
58_I199_T1.1821.00
88_I217_T1.1801.00
115_I119_G1.1771.00
90_L111_V1.1711.00
16_S197_A1.1621.00
112_A148_I1.1621.00
127_V130_L1.1521.00
168_L253_P1.1511.00
147_W151_I1.1511.00
30_I34_I1.1491.00
154_A257_T1.1481.00
80_I188_I1.1451.00
148_I228_I1.1381.00
160_G280_H1.1371.00
17_L201_G1.1361.00
35_G38_D1.1321.00
21_L201_G1.1281.00
147_W230_S1.1281.00
258_T262_I1.1241.00
63_V81_T1.1231.00
144_T148_I1.1221.00
36_A39_Q1.1211.00
105_F149_V1.1151.00
173_L192_S1.1101.00
153_N156_N1.1091.00
140_A144_T1.1061.00
87_I112_A1.0941.00
36_A40_P1.0941.00
155_I165_A1.0911.00
180_A188_I1.0911.00
152_T220_L1.0911.00
19_T65_G1.0901.00
256_D280_H1.0851.00
121_K140_A1.0771.00
301_G305_S1.0761.00
150_G257_T1.0761.00
201_G205_Y1.0711.00
172_G249_I1.0681.00
151_I254_I1.0551.00
86_I107_I1.0551.00
177_A196_I1.0401.00
29_R32_I1.0391.00
194_V197_A1.0351.00
116_V145_V1.0351.00
87_I224_Y1.0321.00
275_D285_A1.0281.00
62_V198_S1.0251.00
172_G250_L1.0221.00
255_F279_I1.0191.00
221_F225_S1.0171.00
112_A149_V1.0151.00
108_Q220_L1.0131.00
165_A253_P1.0121.00
26_I29_R1.0111.00
84_A225_S1.0091.00
171_I301_G1.0031.00
50_M210_A1.0031.00
13_F197_A0.9981.00
50_M213_F0.9951.00
61_G64_A0.9931.00
82_V86_I0.9851.00
166_A214_M0.9841.00
20_V24_T0.9831.00
260_A277_S0.9771.00
91_G220_L0.9701.00
161_L294_V0.9581.00
197_A201_G0.9571.00
79_A118_T0.9561.00
248_I308_A0.9551.00
158_I168_L0.9551.00
168_L252_V0.9541.00
22_I26_I0.9531.00
115_I148_I0.9521.00
87_I111_V0.9501.00
150_G254_I0.9481.00
177_A180_A0.9471.00
83_G111_V0.9441.00
257_T261_I0.9421.00
13_F193_L0.9421.00
108_Q152_T0.9401.00
108_Q149_V0.9391.00
105_F109_L0.9381.00
169_S226_I0.9381.00
175_T309_I0.9371.00
254_I257_T0.9361.00
52_R217_T0.9351.00
108_Q153_N0.9351.00
24_T201_G0.9331.00
104_K152_T0.9291.00
37_V49_I0.9281.00
204_F296_V0.9231.00
260_A264_R0.9221.00
28_K211_K0.9171.00
203_L207_F0.9141.00
97_Y100_S0.9111.00
25_P205_Y0.9101.00
83_G228_I0.9101.00
83_G115_I0.9041.00
288_L292_M0.8931.00
174_S178_V0.8901.00
177_A181_L0.8901.00
169_S199_T0.8891.00
180_A189_L0.8851.00
173_L199_T0.8841.00
177_A189_L0.8801.00
104_K157_L0.8781.00
170_V199_T0.8771.00
252_V297_I0.8741.00
23_I57_A0.8701.00
176_I230_S0.8691.00
59_F84_A0.8651.00
62_V84_A0.8631.00
249_I305_S0.8611.00
171_I302_F0.8570.99
200_L204_F0.8500.99
62_V221_F0.8480.99
249_I308_A0.8470.99
35_G39_Q0.8460.99
179_M249_I0.8440.99
262_I265_I0.8430.99
208_H290_H0.8370.99
176_I249_I0.8340.99
116_V120_L0.8330.99
284_M287_G0.8300.99
17_L21_L0.8250.99
87_I152_T0.8170.99
19_T64_A0.8110.99
116_V144_T0.8000.99
80_I225_S0.8000.99
66_V77_M0.7930.99
157_L261_I0.7920.99
139_M143_L0.7910.99
80_I84_A0.7890.99
146_L150_G0.7860.99
26_I30_I0.7850.99
80_I228_I0.7800.99
104_K107_I0.7770.99
102_K106_L0.7740.99
155_I250_L0.7730.99
166_A202_F0.7640.99
17_L200_L0.7640.99
93_L96_K0.7610.99
87_I107_I0.7610.99
165_A222_L0.7580.99
172_G305_S0.7570.99
116_V119_G0.7570.99
207_F291_R0.7550.99
21_L205_Y0.7540.99
191_L229_L0.7490.99
123_D135_E0.7460.99
143_L147_W0.7460.99
281_H284_M0.7450.99
172_G253_P0.7440.99
283_L297_I0.7420.99
213_F216_D0.7350.98
42_N46_H0.7350.98
39_Q49_I0.7340.98
259_F263_R0.7340.98
16_S198_S0.7330.98
266_L269_Q0.7320.98
11_V15_V0.7310.98
12_A190_S0.7300.98
264_R278_H0.7300.98
82_V114_M0.7290.98
208_H294_V0.7280.98
34_I38_D0.7280.98
299_L303_I0.7270.98
155_I172_G0.7240.98
45_V290_H0.7230.98
176_I233_G0.7230.98
307_S311_L0.7230.98
124_F135_E0.7200.98
250_L253_P0.7140.98
161_L293_S0.7130.98
116_V141_Y0.7110.98
156_N213_F0.7100.98
306_I310_V0.7090.98
135_E139_M0.7060.98
304_F308_A0.7040.98
20_V58_I0.7040.98
71_I74_E0.6980.98
300_I304_F0.6970.98
141_Y145_V0.6960.98
24_T28_K0.6940.98
86_I90_L0.6930.98
158_I280_H0.6910.98
31_A37_V0.6890.98
62_V173_L0.6890.98
38_D44_K0.6880.98
283_L288_L0.6870.98
19_T23_I0.6860.98
171_I175_T0.6860.98
151_I227_S0.6860.98
253_P275_D0.6850.98
303_I307_S0.6820.97
13_F196_I0.6790.97
288_L293_S0.6790.97
18_L22_I0.6790.97
10_V14_I0.6780.97
35_G40_P0.6720.97
103_V106_L0.6720.97
150_G154_A0.6710.97
151_I230_S0.6710.97
275_D280_H0.6680.97
153_N216_D0.6670.97
88_I221_F0.6670.97
309_I312_K0.6670.97
190_S194_V0.6650.97
265_I277_S0.6640.97
87_I108_Q0.6630.97
157_L264_R0.6600.97
151_I250_L0.6600.97
250_L254_I0.6600.97
12_A65_G0.6580.97
73_T110_G0.6560.97
88_I92_I0.6540.97
62_V66_V0.6540.97
137_G142_P0.6540.97
249_I301_G0.6530.97
92_I217_T0.6510.97
267_N270_P0.6510.97
275_D278_H0.6500.97
85_F89_V0.6490.97
230_S246_P0.6480.97
127_V132_E0.6480.97
173_L225_S0.6480.97
252_V301_G0.6380.96
28_K212_I0.6360.96
176_I192_S0.6340.96
100_S104_K0.6330.96
56_L217_T0.6330.96
128_P131_T0.6330.96
267_N277_S0.6310.96
84_A191_L0.6250.96
115_I118_T0.6250.96
179_M312_K0.6250.96
260_A281_H0.6250.96
31_A51_P0.6240.96
62_V191_L0.6240.96
152_T219_S0.6230.96
136_L140_A0.6220.96
13_F17_L0.6220.96
65_G68_A0.6210.96
157_L260_A0.6190.96
15_V65_G0.6190.96
56_L88_I0.6180.96
124_F133_R0.6150.95
293_S297_I0.6140.95
126_S129_F0.6120.95
53_M92_I0.6070.95
219_S264_R0.6050.95
256_D264_R0.6030.95
294_V298_Y0.6020.95
224_Y228_I0.6020.95
35_G41_S0.6020.95
167_G294_V0.6000.95
158_I253_P0.6000.95
178_V309_I0.5970.95
38_D52_R0.5960.95
170_V174_S0.5960.95
289_S293_S0.5950.95
54_G202_F0.5950.95
159_D218_G0.5940.94
104_K216_D0.5940.94
263_R275_D0.5910.94
42_N45_V0.5860.94
161_L298_Y0.5850.94
9_I12_A0.5850.94
189_L193_L0.5850.94
165_A214_M0.5840.94
262_I266_L0.5840.94
142_P145_V0.5810.94
90_L220_L0.5810.94
23_I61_G0.5800.94
159_D214_M0.5790.94
61_G198_S0.5780.94
268_K271_I0.5780.94
188_I232_L0.5770.94
101_A105_F0.5760.94
14_I18_L0.5750.93
296_V299_L0.5740.93
66_V191_L0.5720.93
16_S65_G0.5710.93
164_L297_I0.5700.93
261_I264_R0.5700.93
65_G69_S0.5670.93
183_G186_V0.5670.93
214_M222_L0.5660.93
275_D281_H0.5650.93
16_S61_G0.5620.93
167_G171_I0.5610.93
58_I62_V0.5600.93
117_S121_K0.5590.92
87_I220_L0.5590.92
53_M96_K0.5570.92
255_F300_I0.5550.92
152_T224_Y0.5540.92
178_V182_S0.5520.92
115_I224_Y0.5500.92
124_F128_P0.5490.92
45_V284_M0.5480.92
202_F214_M0.5460.92
118_T122_M0.5460.92
39_Q48_K0.5460.92
165_A202_F0.5450.92
27_V30_I0.5440.91
284_M293_S0.5430.91
118_T121_K0.5380.91
59_F62_V0.5370.91
108_Q219_S0.5350.91
152_T227_S0.5340.91
291_R295_L0.5310.90
150_G258_T0.5310.90
112_A227_S0.5290.90
279_I297_I0.5290.90
45_V161_L0.5280.90
263_R277_S0.5280.90
101_A264_R0.5260.90
207_F292_M0.5240.90
162_D214_M0.5240.90
204_F211_K0.5230.90
246_P257_T0.5230.90
217_T220_L0.5230.90
31_A53_M0.5210.90
261_I265_I0.5210.90
231_L235_Y0.5210.90
52_R290_H0.5190.89
179_M233_G0.5170.89
113_I141_Y0.5170.89
204_F299_L0.5150.89
308_A312_K0.5150.89
253_P280_H0.5150.89
179_M235_Y0.5140.89
290_H294_V0.5140.89
40_P48_K0.5100.89
256_D283_L0.5070.88
83_G86_I0.5070.88
192_S225_S0.5060.88
158_I260_A0.5050.88
148_I152_T0.5040.88
180_A192_S0.5040.88
159_D165_A0.5030.88
24_T31_A0.5030.88
135_E138_W0.5000.88
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4j72A 2 0.8073 100 0.239 Contact Map
2rddB 1 0.1034 11.1 0.966 Contact Map
3j01B 1 0.1899 9.7 0.967 Contact Map
2ls4A 1 0.067 8.1 0.968 Contact Map
2m20A 2 0.1201 7.9 0.969 Contact Map
1j27A 2 0.1034 5.7 0.971 Contact Map
4p6zV 1 0 5.4 0.971 Contact Map
3echC 1 0.0391 4.8 0.972 Contact Map
4eneA 2 0.6648 4.4 0.972 Contact Map
3ne5A 3 0.1927 4.2 0.972 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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