GREMLIN Database
RECQ - Probable ATP-dependent DNA helicase RecQ
UniProt: O34748 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 591 (508)
Sequences: 7504 (5706)
Seq/√Len: 253.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
255_V283_V5.5021.00
29_V172_M4.1011.00
23_D27_R3.8481.00
275_R280_E3.7291.00
237_T243_A3.5901.00
271_E275_R3.2541.00
417_I476_I3.1501.00
528_K532_A3.0641.00
209_F318_A2.9191.00
408_R411_Q2.8111.00
258_G281_L2.7581.00
521_E524_R2.7421.00
51_Q78_L2.7041.00
204_R207_L2.6051.00
526_V530_I2.5381.00
84_N110_K2.5311.00
237_T246_I2.5231.00
408_R412_M2.5221.00
224_Y331_V2.4601.00
246_I285_V2.4251.00
488_V492_G2.4211.00
218_D249_R2.3951.00
202_F205_E2.3811.00
221_I303_L2.3591.00
247_Y257_A2.3531.00
86_A100_R2.3371.00
342_Q346_I2.3341.00
265_A268_V2.3271.00
394_C398_T2.3231.00
520_F524_R2.3031.00
222_D253_N2.2811.00
437_K442_L2.2501.00
495_V502_V2.2221.00
413_V467_I2.1781.00
264_L268_V2.1781.00
394_C397_C2.1571.00
376_Q380_L2.1561.00
225_V255_V2.1521.00
114_I119_L2.1311.00
233_G301_F2.1111.00
428_M446_F2.1111.00
342_Q345_L2.1071.00
258_G272_Q2.1061.00
207_L330_C2.0661.00
105_K130_G2.0431.00
205_E209_F2.0331.00
259_R272_Q2.0071.00
93_S96_E2.0041.00
450_S454_I1.9771.00
489_S492_G1.9691.00
62_I136_V1.9591.00
8_L52_I1.9111.00
65_S74_Q1.9081.00
28_L36_T1.9001.00
30_T56_M1.8951.00
109_Y112_F1.8901.00
228_N231_E1.8791.00
458_Q462_E1.8701.00
72_K76_D1.8701.00
25_A38_C1.8491.00
244_D259_R1.8441.00
203_S207_L1.8361.00
240_R263_G1.8301.00
258_G275_R1.8231.00
455_L463_I1.8211.00
352_E355_Q1.8121.00
249_R253_N1.7961.00
204_R211_V1.7881.00
31_E34_Q1.7741.00
377_R381_M1.7661.00
256_R282_Q1.7401.00
216_N219_R1.7321.00
272_Q284_M1.7201.00
377_R390_A1.6971.00
410_A414_L1.6891.00
78_L111_L1.6791.00
21_G38_C1.6781.00
358_D361_K1.6771.00
204_R208_T1.6671.00
209_F213_K1.6621.00
270_K274_E1.6361.00
393_Q397_C1.6331.00
494_N499_E1.6161.00
211_V368_Y1.6121.00
204_R209_F1.6091.00
373_D377_R1.5961.00
495_V498_G1.5901.00
28_L34_Q1.5861.00
342_Q349_S1.5841.00
86_A109_Y1.5841.00
58_E132_D1.5781.00
494_N500_L1.5721.00
376_Q383_F1.5671.00
221_I305_A1.5631.00
192_I195_E1.5521.00
141_A173_A1.5401.00
459_S462_E1.5281.00
361_K366_V1.5191.00
346_I349_S1.5151.00
526_V529_E1.4941.00
290_F294_I1.4921.00
430_A434_A1.4851.00
225_V301_F1.4791.00
365_M369_C1.4771.00
380_L383_F1.4761.00
516_N519_L1.4741.00
445_G448_D1.4711.00
129_Q164_E1.4461.00
27_R31_E1.4371.00
268_V272_Q1.4241.00
209_F212_V1.4091.00
28_L196_N1.4031.00
485_T489_S1.4021.00
78_L113_Y1.3971.00
468_E471_I1.3841.00
349_S355_Q1.3761.00
363_R367_D1.3631.00
120_T154_S1.3621.00
446_F449_L1.3611.00
341_V345_L1.3601.00
529_E532_A1.3581.00
490_S493_R1.3571.00
54_A61_T1.3551.00
218_D246_I1.3531.00
492_G496_L1.3531.00
517_D521_E1.3511.00
436_S439_K1.3471.00
438_N441_V1.3461.00
310_D313_S1.3411.00
409_E413_V1.3321.00
492_G495_V1.3281.00
496_L502_V1.3211.00
439_K443_E1.3201.00
407_T410_A1.3171.00
375_L378_F1.3161.00
393_Q400_T1.3091.00
274_E278_N1.3011.00
203_S209_F1.2961.00
527_R531_A1.2921.00
495_V499_E1.2881.00
205_E211_V1.2871.00
373_D381_M1.2851.00
218_D253_N1.2841.00
235_V303_L1.2791.00
519_L523_L1.2781.00
461_G464_S1.2771.00
8_L56_M1.2721.00
62_I133_V1.2711.00
226_Q253_N1.2691.00
241_K245_R1.2641.00
397_C401_R1.2591.00
157_N160_I1.2551.00
478_M482_T1.2541.00
72_K274_E1.2531.00
318_A330_C1.2531.00
453_G456_K1.2531.00
242_E306_Q1.2481.00
372_E375_L1.2421.00
494_N497_K1.2341.00
60_T110_K1.2341.00
208_T211_V1.2321.00
95_Q98_Y1.2271.00
183_H199_Y1.2271.00
375_L382_Y1.2251.00
427_T430_A1.2241.00
483_F486_L1.2231.00
375_L379_I1.2221.00
34_Q196_N1.2111.00
217_K306_Q1.2101.00
485_T488_V1.2101.00
436_S452_Y1.2061.00
425_G429_V1.2051.00
413_V416_C1.2031.00
475_F478_M1.2011.00
345_L349_S1.1961.00
26_I52_I1.1951.00
203_S211_V1.1951.00
377_R380_L1.1901.00
395_G400_T1.1891.00
366_V369_C1.1871.00
202_F209_F1.1861.00
202_F206_N1.1821.00
410_A413_V1.1791.00
499_E502_V1.1771.00
341_V344_F1.1751.00
351_H354_K1.1741.00
374_C382_Y1.1711.00
246_I305_A1.1701.00
219_R223_E1.1691.00
522_R525_M1.1681.00
64_I114_I1.1631.00
424_F429_V1.1621.00
429_V432_V1.1621.00
494_N498_G1.1611.00
436_S442_L1.1601.00
524_R530_I1.1481.00
348_Q355_Q1.1461.00
411_Q414_L1.1441.00
38_C174_L1.1421.00
480_D483_F1.1341.00
237_T285_V1.1311.00
367_D370_H1.1311.00
203_S208_T1.1301.00
344_F348_Q1.1301.00
258_G284_M1.1291.00
420_M428_M1.1281.00
251_K257_A1.1251.00
86_A112_F1.1191.00
433_L436_S1.1171.00
412_M415_S1.1141.00
357_Q361_K1.1071.00
328_S332_L1.1061.00
202_F207_L1.1051.00
179_T182_V1.1051.00
480_D484_P1.1031.00
470_L474_D1.1021.00
491_K500_L1.1011.00
418_I421_K1.0991.00
413_V417_I1.0961.00
187_C197_T1.0961.00
235_V283_V1.0941.00
361_K364_Q1.0911.00
471_I474_D1.0901.00
374_C383_F1.0871.00
156_R189_Q1.0861.00
396_N399_D1.0821.00
247_Y259_R1.0791.00
380_L384_G1.0761.00
489_S493_R1.0761.00
431_Q438_N1.0741.00
483_F487_F1.0731.00
516_N520_F1.0721.00
366_V370_H1.0701.00
468_E472_S1.0691.00
449_L453_G1.0641.00
25_A198_V1.0631.00
375_L380_L1.0631.00
362_L369_C1.0611.00
409_E414_L1.0601.00
425_G428_M1.0561.00
243_A259_R1.0561.00
429_V433_L1.0541.00
527_R530_I1.0511.00
466_F469_F1.0491.00
482_T485_T1.0481.00
57_F135_L1.0481.00
392_G395_G1.0471.00
428_M432_V1.0411.00
406_V410_A1.0361.00
519_L522_R1.0341.00
490_S494_N1.0281.00
104_L112_F1.0281.00
230_H282_Q1.0261.00
222_D249_R1.0241.00
207_L210_K1.0201.00
393_Q398_T1.0181.00
416_C419_R1.0151.00
397_C400_T1.0131.00
404_H409_E1.0131.00
250_L285_V1.0121.00
428_M440_K1.0121.00
346_I350_E1.0111.00
520_F523_L1.0081.00
350_E355_Q1.0081.00
486_L490_S1.0081.00
523_L527_R1.0071.00
493_R499_E1.0031.00
466_F470_L1.0021.00
75_V85_A1.0021.00
410_A417_I1.0011.00
391_C394_C1.0011.00
343_R346_I1.0001.00
459_S463_I0.9991.00
204_R210_K0.9971.00
493_R497_K0.9961.00
350_E354_K0.9921.00
195_E198_V0.9911.00
462_E466_F0.9911.00
525_M532_A0.9891.00
201_G385_E0.9891.00
376_Q382_Y0.9851.00
484_P490_S0.9831.00
463_I466_F0.9801.00
396_N400_T0.9791.00
524_R531_A0.9771.00
451_T454_I0.9721.00
184_D188_K0.9711.00
142_H292_M0.9691.00
440_K444_N0.9691.00
470_L475_F0.9671.00
206_N209_F0.9641.00
412_M418_I0.9631.00
101_L105_K0.9611.00
392_G397_C0.9591.00
365_M368_Y0.9581.00
455_L467_I0.9561.00
375_L384_G0.9561.00
99_E102_N0.9541.00
431_Q435_G0.9531.00
481_G485_T0.9521.00
518_E522_R0.9521.00
350_E353_E0.9481.00
426_K429_V0.9461.00
491_K495_V0.9431.00
203_S206_N0.9411.00
522_R526_V0.9411.00
414_L418_I0.9401.00
456_K459_S0.9381.00
348_Q351_H0.9361.00
479_S484_P0.9341.00
378_F381_M0.9331.00
87_Y91_T0.9301.00
29_V36_T0.9301.00
389_D392_G0.9271.00
210_K213_K0.9261.00
272_Q281_L0.9261.00
94_N98_Y0.9241.00
379_I382_Y0.9191.00
490_S495_V0.9191.00
372_E380_L0.9171.00
429_V436_S0.9161.00
414_L417_I0.9151.00
523_L531_A0.9121.00
379_I383_F0.9121.00
182_V186_I0.9111.00
460_V463_I0.9111.00
180_P183_H0.9111.00
424_F428_M0.9111.00
64_I119_L0.9111.00
373_D376_Q0.9071.00
372_E376_Q0.9021.00
223_E227_N0.8961.00
365_M370_H0.8931.00
54_A111_L0.8901.00
426_K432_V0.8891.00
415_S418_I0.8881.00
491_K494_N0.8881.00
398_T401_R0.8871.00
409_E412_M0.8851.00
87_Y92_Q0.8831.00
359_L362_L0.8811.00
393_Q396_N0.8801.00
335_S340_M0.8771.00
425_G432_V0.8751.00
471_I476_I0.8691.00
363_R366_V0.8681.00
419_R451_T0.8681.00
486_L489_S0.8671.00
32_A36_T0.8661.00
342_Q352_E0.8640.99
479_S482_T0.8630.99
457_H460_V0.8630.99
98_Y102_N0.8620.99
454_I458_Q0.8600.99
378_F382_Y0.8590.99
8_L11_H0.8570.99
376_Q384_G0.8560.99
497_K501_S0.8560.99
426_K430_A0.8550.99
471_I475_F0.8530.99
394_C400_T0.8520.99
454_I457_H0.8490.99
208_T212_V0.8490.99
104_L131_I0.8480.99
225_V233_G0.8480.99
35_N193_Q0.8470.99
343_R347_E0.8470.99
242_E245_R0.8450.99
207_L211_V0.8440.99
205_E212_V0.8430.99
466_F473_D0.8430.99
50_Y74_Q0.8420.99
515_E519_L0.8410.99
465_D471_I0.8410.99
379_I384_G0.8380.99
392_G396_N0.8370.99
337_Q340_M0.8350.99
260_Y290_F0.8350.99
416_C420_M0.8310.99
368_Y371_T0.8300.99
202_F208_T0.8270.99
374_C379_I0.8270.99
248_E251_K0.8230.99
460_V464_S0.8230.99
411_Q417_I0.8230.99
523_L528_K0.8220.99
387_E390_A0.8220.99
135_L172_M0.8210.99
515_E521_E0.8200.99
412_M419_R0.8190.99
248_E252_R0.8190.99
341_V346_I0.8180.99
488_V491_K0.8180.99
514_T517_D0.8160.99
226_Q255_V0.8140.99
514_T518_E0.8140.99
224_Y301_F0.8130.99
446_F451_T0.8120.99
497_K500_L0.8120.99
418_I422_E0.8110.99
490_S498_G0.8090.99
390_A393_Q0.8090.99
428_M444_N0.8080.99
361_K365_M0.8060.99
183_H187_C0.8030.99
486_L496_L0.8020.99
519_L526_V0.8020.99
367_D371_T0.8000.99
411_Q415_S0.8000.99
446_F450_S0.8000.99
102_N106_E0.8000.99
321_A328_S0.7980.99
163_R191_H0.7970.99
433_L440_K0.7950.99
452_Y457_H0.7930.99
467_I472_S0.7910.99
428_M441_V0.7900.99
492_G498_G0.7880.99
239_T262_G0.7860.99
483_F493_R0.7850.99
479_S483_F0.7850.99
411_Q419_R0.7840.99
351_H355_Q0.7840.99
303_L331_V0.7820.99
515_E530_I0.7810.99
400_T403_A0.7790.99
374_C378_F0.7750.99
464_S470_L0.7740.99
218_D305_A0.7740.99
519_L529_E0.7730.99
204_R213_K0.7700.99
488_V496_L0.7700.99
457_H461_G0.7690.99
458_Q463_I0.7610.99
218_D245_R0.7590.99
349_S352_E0.7580.99
456_K460_V0.7580.99
239_T242_E0.7580.99
488_V494_N0.7570.99
194_K197_T0.7570.99
393_Q401_R0.7570.99
395_G399_D0.7570.99
208_T329_E0.7560.99
67_L292_M0.7550.99
524_R527_R0.7540.99
446_F453_G0.7540.99
449_L452_Y0.7540.99
401_R404_H0.7530.99
408_R418_I0.7530.99
29_V174_L0.7520.99
372_E381_M0.7520.99
523_L526_V0.7510.99
496_L499_E0.7510.99
415_S419_R0.7510.99
406_V466_F0.7500.99
357_Q360_K0.7490.99
489_S496_L0.7480.99
517_D522_R0.7470.99
375_L383_F0.7460.99
424_F432_V0.7450.99
162_F171_I0.7430.98
217_K305_A0.7430.98
84_N108_A0.7390.98
484_P492_G0.7390.98
432_V441_V0.7370.98
50_Y174_L0.7370.98
484_P488_V0.7360.98
340_M343_R0.7350.98
521_E529_E0.7350.98
437_K441_V0.7340.98
498_G502_V0.7330.98
518_E521_E0.7320.98
204_R212_V0.7310.98
374_C380_L0.7300.98
489_S502_V0.7300.98
160_I163_R0.7300.98
453_G470_L0.7290.98
182_V185_D0.7280.98
453_G458_Q0.7280.98
519_L527_R0.7280.98
77_A295_D0.7270.98
432_V437_K0.7250.98
15_Y48_I0.7240.98
362_L366_V0.7220.98
231_E300_R0.7200.98
517_D530_I0.7180.98
374_C377_R0.7160.98
469_F472_S0.7160.98
466_F475_F0.7150.98
488_V495_V0.7150.98
247_Y251_K0.7130.98
432_V435_G0.7130.98
524_R528_K0.7110.98
473_D477_R0.7110.98
34_Q194_K0.7100.98
178_A322_G0.7090.98
477_R480_D0.7040.98
406_V409_E0.7030.98
205_E208_T0.7000.98
79_E86_A0.7000.98
243_A285_V0.6990.98
409_E416_C0.6990.98
345_L348_Q0.6980.98
475_F479_S0.6970.98
520_F526_V0.6960.98
334_F342_Q0.6960.98
407_T411_Q0.6940.98
408_R417_I0.6930.98
304_H318_A0.6930.98
72_K270_K0.6920.98
49_C53_P0.6910.98
467_I471_I0.6910.98
474_D477_R0.6900.98
410_A416_C0.6900.98
218_D222_D0.6900.98
473_D476_I0.6880.98
468_E475_F0.6870.97
356_K365_M0.6860.97
408_R414_L0.6860.97
441_V446_F0.6860.97
465_D469_F0.6860.97
203_S376_Q0.6840.97
481_G484_P0.6840.97
464_S468_E0.6830.97
166_H169_P0.6810.97
436_S440_K0.6810.97
467_I476_I0.6780.97
424_F444_N0.6780.97
420_M432_V0.6780.97
446_F454_I0.6770.97
479_S488_V0.6770.97
202_F211_V0.6760.97
135_L174_L0.6760.97
470_L476_I0.6750.97
413_V419_R0.6730.97
526_V531_A0.6720.97
376_Q379_I0.6700.97
471_I479_S0.6690.97
372_E378_F0.6690.97
345_L355_Q0.6680.97
523_L530_I0.6650.97
469_F474_D0.6630.97
376_Q385_E0.6620.97
372_E382_Y0.6620.97
360_K365_M0.6610.97
498_G501_S0.6610.97
78_L85_A0.6610.97
374_C384_G0.6600.97
479_S485_T0.6600.97
475_F495_V0.6590.97
32_A57_F0.6590.97
515_E518_E0.6580.97
451_T455_L0.6580.97
369_C379_I0.6560.97
425_G435_G0.6560.97
75_V79_E0.6550.97
521_E527_R0.6540.97
428_M436_S0.6530.97
358_D367_D0.6520.97
514_T524_R0.6510.97
428_M435_G0.6500.96
224_Y333_L0.6500.96
332_L335_S0.6490.96
424_F446_F0.6480.96
463_I467_I0.6480.96
374_C381_M0.6470.96
142_H316_Q0.6430.96
8_L12_Y0.6430.96
520_F528_K0.6420.96
366_V371_T0.6420.96
450_S453_G0.6420.96
349_S354_K0.6410.96
416_C451_T0.6390.96
257_A285_V0.6390.96
430_A433_L0.6380.96
220_F223_E0.6360.96
516_N526_V0.6360.96
495_V500_L0.6360.96
405_D410_A0.6350.96
361_K367_D0.6350.96
335_S338_D0.6350.96
516_N522_R0.6340.96
92_Q100_R0.6340.96
345_L352_E0.6330.96
519_L528_K0.6320.96
452_Y462_E0.6310.96
478_M481_G0.6310.96
375_L395_G0.6310.96
520_F529_E0.6290.96
492_G502_V0.6290.96
452_Y456_K0.6280.96
267_D271_E0.6260.96
525_M528_K0.6250.96
487_F490_S0.6240.96
517_D529_E0.6230.96
61_T135_L0.6220.96
441_V444_N0.6220.96
455_L458_Q0.6220.96
402_A405_D0.6200.95
503_A529_E0.6200.95
427_T437_K0.6190.95
382_Y385_E0.6190.95
521_E531_A0.6180.95
60_T134_P0.6160.95
485_T490_S0.6160.95
207_L213_K0.6150.95
524_R529_E0.6130.95
518_E530_I0.6100.95
476_I480_D0.6090.95
488_V498_G0.6080.95
515_E520_F0.6080.95
390_A394_C0.6060.95
452_Y455_L0.6020.95
361_K369_C0.6010.95
12_Y83_I0.6000.95
220_F224_Y0.5970.94
459_S464_S0.5970.94
206_N212_V0.5960.94
471_I486_L0.5930.94
304_H332_L0.5920.94
187_C192_I0.5920.94
490_S496_L0.5900.94
476_I479_S0.5890.94
407_T414_L0.5890.94
361_K379_I0.5870.94
479_S487_F0.5860.94
366_V372_E0.5860.94
519_L524_R0.5850.94
205_E210_K0.5850.94
419_R450_S0.5840.94
212_V220_F0.5840.94
232_A300_R0.5830.94
424_F430_A0.5820.94
114_I124_F0.5820.94
212_V333_L0.5820.94
467_I470_L0.5820.94
432_V446_F0.5820.94
480_D489_S0.5810.94
415_S421_K0.5810.94
77_A80_E0.5790.93
420_M424_F0.5790.93
205_E213_K0.5790.93
459_S466_F0.5780.93
466_F472_S0.5780.93
97_I118_R0.5770.93
377_R384_G0.5760.93
67_L117_E0.5760.93
273_Q296_K0.5750.93
485_T495_V0.5740.93
494_N502_V0.5710.93
403_A406_V0.5680.93
433_L441_V0.5670.93
433_L437_K0.5660.93
420_M433_L0.5650.93
487_F491_K0.5640.93
391_C397_C0.5640.93
347_E351_H0.5620.92
429_V438_N0.5600.92
453_G463_I0.5580.92
515_E528_K0.5580.92
457_H463_I0.5580.92
35_N162_F0.5570.92
518_E529_E0.5570.92
422_E425_G0.5560.92
370_H379_I0.5560.92
449_L454_I0.5550.92
407_T415_S0.5540.92
193_Q196_N0.5540.92
458_Q471_I0.5530.92
444_N447_S0.5500.92
359_L363_R0.5490.92
489_S494_N0.5480.91
491_K496_L0.5480.91
489_S500_L0.5480.91
320_R323_R0.5480.91
428_M437_K0.5460.91
264_L272_Q0.5450.91
461_G465_D0.5450.91
200_T204_R0.5440.91
369_C380_L0.5430.91
411_Q420_M0.5420.91
421_K425_G0.5420.91
514_T521_E0.5420.91
359_L368_Y0.5410.91
425_G437_K0.5410.91
434_A463_I0.5400.91
408_R419_R0.5390.91
333_L336_P0.5390.91
486_L497_K0.5380.91
465_D468_E0.5380.91
429_V434_A0.5370.91
359_L370_H0.5350.91
412_M416_C0.5350.91
202_F213_K0.5340.90
520_F525_M0.5340.90
525_M529_E0.5340.90
286_A290_F0.5330.90
268_V271_E0.5330.90
411_Q418_I0.5320.90
374_C385_E0.5320.90
522_R529_E0.5310.90
368_Y372_E0.5310.90
21_G24_E0.5310.90
418_I488_V0.5300.90
27_R30_T0.5300.90
201_G204_R0.5290.90
472_S475_F0.5290.90
357_Q370_H0.5290.90
477_R489_S0.5290.90
390_A397_C0.5290.90
517_D524_R0.5270.90
420_M429_V0.5270.90
490_S497_K0.5260.90
454_I463_I0.5260.90
462_E467_I0.5260.90
375_L381_M0.5260.90
76_D80_E0.5260.90
477_R481_G0.5250.90
364_Q367_D0.5250.90
447_S450_S0.5230.90
518_E525_M0.5230.90
407_T416_C0.5230.90
50_Y53_P0.5230.90
472_S477_R0.5210.89
452_Y463_I0.5210.89
375_L386_K0.5210.89
431_Q434_A0.5200.89
357_Q366_V0.5200.89
238_A306_Q0.5190.89
377_R383_F0.5180.89
374_C394_C0.5180.89
455_L475_F0.5180.89
358_D366_V0.5180.89
486_L495_V0.5170.89
449_L455_L0.5160.89
160_I164_E0.5160.89
428_M433_L0.5140.89
466_F476_I0.5140.89
431_Q436_S0.5130.89
387_E392_G0.5130.89
67_L73_D0.5120.89
517_D528_K0.5110.88
450_S459_S0.5110.88
121_S124_F0.5100.88
54_A135_L0.5100.88
462_E472_S0.5100.88
161_L166_H0.5100.88
381_M386_K0.5090.88
469_F477_R0.5080.88
221_I235_V0.5060.88
524_R532_A0.5040.88
460_V465_D0.5040.88
301_F331_V0.5030.88
463_I470_L0.5030.88
451_T459_S0.5030.88
517_D527_R0.5020.88
378_F385_E0.5010.87
448_D452_Y0.5010.87
455_L466_F0.5010.87
187_C193_Q0.5010.87
361_K368_Y0.5010.87
520_F527_R0.5000.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1oywA 1 0.8596 100 0.291 Contact Map
4q48A 1 0.8443 100 0.305 Contact Map
4o3mA 1 0.9577 100 0.308 Contact Map
2v1xA 1 0.8308 100 0.343 Contact Map
4pxaA 1 0.6041 100 0.388 Contact Map
4ljyA 1 0.6159 100 0.397 Contact Map
4nhoA 1 0.5905 100 0.398 Contact Map
2db3A 1 0.5939 100 0.4 Contact Map
4d25A 1 0.5922 100 0.411 Contact Map
4c9bA 1 0.5939 100 0.413 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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