RECQ - BACSU - GREMLIN Contacts

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RECQ - Probable ATP-dependent DNA helicase RecQ

UniProt:	O34748	Sequences: MLHRAQSLLAHYFGYEKFRSGQDEAIRLVTEARQNTACIMPTGGGKSICYQIPALMFEGTTIVISPLISLMKDQVDALEEAGINAAYINSTQSNQEIYERLNGLKEGAYKLFYITPERLTSIEFIRILQGIDVPLVAIDEAHCISQWGHDFRPSYRNIEILFRELHDKPVIMALTATATPEVHDDICKQLHIQKENTVYTGFSRENLTFKVVKGENKDRFIDEYVQNNRHEAGIVYTATRKEADRIYERLKRNQVRAGRYHGGLADDVRKEQQERFLNDELQVMVATSAFGMGIDKSNIRFVLHAQIPKDMESYYQEAGRAGRDGLASECVLLFSPQDIMVQRFLIEQSEHEEKQKQDLKKLRQMVDYCHTEDCLQRFILMYFGEKEPDACGQCGNCTDTRAAHDVTREAQMVLSCIIRMKERFGKTMVAQVLAGSKNKKVLENGFSDLSTYGILKHQSVGEISDFIEFLISDDFIRMSDGTFPTLFVSSKGRNVLKGELSVARKEALKAAAITENDELFERLRMVRKEIAAEQGVPPFVVFSDQTLKEMSGKQPVNDDELLSIKGVGEQKRAKYGRLFLQEIQAYARMTD	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	591 (508)
Sequences:	7504 (5706)
Seq/√Len:	253.2

ECOLI - RECQ DEAD RECG YFJK YEJH DBPA RAPA RHLE SRMB RHLB
BACSU - RECQ RECS RECG YPRA CSHA DBPA CSHB COMFA YWQA YFML
HALSA - Q9HN80 HELS Q9HNB2 RAD25 O52003 Q9HMW5 O51997
SULSO - Q981C8 Q97X74 HELS Q97YC4 Q97ZF9 HELX Q97Y93 Q97WW1 Q97X64 Q97WT0 Q980C0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
255_V	283_V	5.502	1.00
29_V	172_M	4.101	1.00
23_D	27_R	3.848	1.00
275_R	280_E	3.729	1.00
237_T	243_A	3.590	1.00
271_E	275_R	3.254	1.00
417_I	476_I	3.150	1.00
528_K	532_A	3.064	1.00
209_F	318_A	2.919	1.00
408_R	411_Q	2.811	1.00
258_G	281_L	2.758	1.00
521_E	524_R	2.742	1.00
51_Q	78_L	2.704	1.00
204_R	207_L	2.605	1.00
526_V	530_I	2.538	1.00
84_N	110_K	2.531	1.00
237_T	246_I	2.523	1.00
408_R	412_M	2.522	1.00
224_Y	331_V	2.460	1.00
246_I	285_V	2.425	1.00
488_V	492_G	2.421	1.00
218_D	249_R	2.395	1.00
202_F	205_E	2.381	1.00
221_I	303_L	2.359	1.00
247_Y	257_A	2.353	1.00
86_A	100_R	2.337	1.00
342_Q	346_I	2.334	1.00
265_A	268_V	2.327	1.00
394_C	398_T	2.323	1.00
520_F	524_R	2.303	1.00
222_D	253_N	2.281	1.00
437_K	442_L	2.250	1.00
495_V	502_V	2.222	1.00
413_V	467_I	2.178	1.00
264_L	268_V	2.178	1.00
394_C	397_C	2.157	1.00
376_Q	380_L	2.156	1.00
225_V	255_V	2.152	1.00
114_I	119_L	2.131	1.00
233_G	301_F	2.111	1.00
428_M	446_F	2.111	1.00
342_Q	345_L	2.107	1.00
258_G	272_Q	2.106	1.00
207_L	330_C	2.066	1.00
105_K	130_G	2.043	1.00
205_E	209_F	2.033	1.00
259_R	272_Q	2.007	1.00
93_S	96_E	2.004	1.00
450_S	454_I	1.977	1.00
489_S	492_G	1.969	1.00
62_I	136_V	1.959	1.00
8_L	52_I	1.911	1.00
65_S	74_Q	1.908	1.00
28_L	36_T	1.900	1.00
30_T	56_M	1.895	1.00
109_Y	112_F	1.890	1.00
228_N	231_E	1.879	1.00
458_Q	462_E	1.870	1.00
72_K	76_D	1.870	1.00
25_A	38_C	1.849	1.00
244_D	259_R	1.844	1.00
203_S	207_L	1.836	1.00
240_R	263_G	1.830	1.00
258_G	275_R	1.823	1.00
455_L	463_I	1.821	1.00
352_E	355_Q	1.812	1.00
249_R	253_N	1.796	1.00
204_R	211_V	1.788	1.00
31_E	34_Q	1.774	1.00
377_R	381_M	1.766	1.00
256_R	282_Q	1.740	1.00
216_N	219_R	1.732	1.00
272_Q	284_M	1.720	1.00
377_R	390_A	1.697	1.00
410_A	414_L	1.689	1.00
78_L	111_L	1.679	1.00
21_G	38_C	1.678	1.00
358_D	361_K	1.677	1.00
204_R	208_T	1.667	1.00
209_F	213_K	1.662	1.00
270_K	274_E	1.636	1.00
393_Q	397_C	1.633	1.00
494_N	499_E	1.616	1.00
211_V	368_Y	1.612	1.00
204_R	209_F	1.609	1.00
373_D	377_R	1.596	1.00
495_V	498_G	1.590	1.00
28_L	34_Q	1.586	1.00
342_Q	349_S	1.584	1.00
86_A	109_Y	1.584	1.00
58_E	132_D	1.578	1.00
494_N	500_L	1.572	1.00
376_Q	383_F	1.567	1.00
221_I	305_A	1.563	1.00
192_I	195_E	1.552	1.00
141_A	173_A	1.540	1.00
459_S	462_E	1.528	1.00
361_K	366_V	1.519	1.00
346_I	349_S	1.515	1.00
526_V	529_E	1.494	1.00
290_F	294_I	1.492	1.00
430_A	434_A	1.485	1.00
225_V	301_F	1.479	1.00
365_M	369_C	1.477	1.00
380_L	383_F	1.476	1.00
516_N	519_L	1.474	1.00
445_G	448_D	1.471	1.00
129_Q	164_E	1.446	1.00
27_R	31_E	1.437	1.00
268_V	272_Q	1.424	1.00
209_F	212_V	1.409	1.00
28_L	196_N	1.403	1.00
485_T	489_S	1.402	1.00
78_L	113_Y	1.397	1.00
468_E	471_I	1.384	1.00
349_S	355_Q	1.376	1.00
363_R	367_D	1.363	1.00
120_T	154_S	1.362	1.00
446_F	449_L	1.361	1.00
341_V	345_L	1.360	1.00
529_E	532_A	1.358	1.00
490_S	493_R	1.357	1.00
54_A	61_T	1.355	1.00
218_D	246_I	1.353	1.00
492_G	496_L	1.353	1.00
517_D	521_E	1.351	1.00
436_S	439_K	1.347	1.00
438_N	441_V	1.346	1.00
310_D	313_S	1.341	1.00
409_E	413_V	1.332	1.00
492_G	495_V	1.328	1.00
496_L	502_V	1.321	1.00
439_K	443_E	1.320	1.00
407_T	410_A	1.317	1.00
375_L	378_F	1.316	1.00
393_Q	400_T	1.309	1.00
274_E	278_N	1.301	1.00
203_S	209_F	1.296	1.00
527_R	531_A	1.292	1.00
495_V	499_E	1.288	1.00
205_E	211_V	1.287	1.00
373_D	381_M	1.285	1.00
218_D	253_N	1.284	1.00
235_V	303_L	1.279	1.00
519_L	523_L	1.278	1.00
461_G	464_S	1.277	1.00
8_L	56_M	1.272	1.00
62_I	133_V	1.271	1.00
226_Q	253_N	1.269	1.00
241_K	245_R	1.264	1.00
397_C	401_R	1.259	1.00
157_N	160_I	1.255	1.00
478_M	482_T	1.254	1.00
72_K	274_E	1.253	1.00
318_A	330_C	1.253	1.00
453_G	456_K	1.253	1.00
242_E	306_Q	1.248	1.00
372_E	375_L	1.242	1.00
494_N	497_K	1.234	1.00
60_T	110_K	1.234	1.00
208_T	211_V	1.232	1.00
95_Q	98_Y	1.227	1.00
183_H	199_Y	1.227	1.00
375_L	382_Y	1.225	1.00
427_T	430_A	1.224	1.00
483_F	486_L	1.223	1.00
375_L	379_I	1.222	1.00
34_Q	196_N	1.211	1.00
217_K	306_Q	1.210	1.00
485_T	488_V	1.210	1.00
436_S	452_Y	1.206	1.00
425_G	429_V	1.205	1.00
413_V	416_C	1.203	1.00
475_F	478_M	1.201	1.00
345_L	349_S	1.196	1.00
26_I	52_I	1.195	1.00
203_S	211_V	1.195	1.00
377_R	380_L	1.190	1.00
395_G	400_T	1.189	1.00
366_V	369_C	1.187	1.00
202_F	209_F	1.186	1.00
202_F	206_N	1.182	1.00
410_A	413_V	1.179	1.00
499_E	502_V	1.177	1.00
341_V	344_F	1.175	1.00
351_H	354_K	1.174	1.00
374_C	382_Y	1.171	1.00
246_I	305_A	1.170	1.00
219_R	223_E	1.169	1.00
522_R	525_M	1.168	1.00
64_I	114_I	1.163	1.00
424_F	429_V	1.162	1.00
429_V	432_V	1.162	1.00
494_N	498_G	1.161	1.00
436_S	442_L	1.160	1.00
524_R	530_I	1.148	1.00
348_Q	355_Q	1.146	1.00
411_Q	414_L	1.144	1.00
38_C	174_L	1.142	1.00
480_D	483_F	1.134	1.00
237_T	285_V	1.131	1.00
367_D	370_H	1.131	1.00
203_S	208_T	1.130	1.00
344_F	348_Q	1.130	1.00
258_G	284_M	1.129	1.00
420_M	428_M	1.128	1.00
251_K	257_A	1.125	1.00
86_A	112_F	1.119	1.00
433_L	436_S	1.117	1.00
412_M	415_S	1.114	1.00
357_Q	361_K	1.107	1.00
328_S	332_L	1.106	1.00
202_F	207_L	1.105	1.00
179_T	182_V	1.105	1.00
480_D	484_P	1.103	1.00
470_L	474_D	1.102	1.00
491_K	500_L	1.101	1.00
418_I	421_K	1.099	1.00
413_V	417_I	1.096	1.00
187_C	197_T	1.096	1.00
235_V	283_V	1.094	1.00
361_K	364_Q	1.091	1.00
471_I	474_D	1.090	1.00
374_C	383_F	1.087	1.00
156_R	189_Q	1.086	1.00
396_N	399_D	1.082	1.00
247_Y	259_R	1.079	1.00
380_L	384_G	1.076	1.00
489_S	493_R	1.076	1.00
431_Q	438_N	1.074	1.00
483_F	487_F	1.073	1.00
516_N	520_F	1.072	1.00
366_V	370_H	1.070	1.00
468_E	472_S	1.069	1.00
449_L	453_G	1.064	1.00
25_A	198_V	1.063	1.00
375_L	380_L	1.063	1.00
362_L	369_C	1.061	1.00
409_E	414_L	1.060	1.00
425_G	428_M	1.056	1.00
243_A	259_R	1.056	1.00
429_V	433_L	1.054	1.00
527_R	530_I	1.051	1.00
466_F	469_F	1.049	1.00
482_T	485_T	1.048	1.00
57_F	135_L	1.048	1.00
392_G	395_G	1.047	1.00
428_M	432_V	1.041	1.00
406_V	410_A	1.036	1.00
519_L	522_R	1.034	1.00
490_S	494_N	1.028	1.00
104_L	112_F	1.028	1.00
230_H	282_Q	1.026	1.00
222_D	249_R	1.024	1.00
207_L	210_K	1.020	1.00
393_Q	398_T	1.018	1.00
416_C	419_R	1.015	1.00
397_C	400_T	1.013	1.00
404_H	409_E	1.013	1.00
250_L	285_V	1.012	1.00
428_M	440_K	1.012	1.00
346_I	350_E	1.011	1.00
520_F	523_L	1.008	1.00
350_E	355_Q	1.008	1.00
486_L	490_S	1.008	1.00
523_L	527_R	1.007	1.00
493_R	499_E	1.003	1.00
466_F	470_L	1.002	1.00
75_V	85_A	1.002	1.00
410_A	417_I	1.001	1.00
391_C	394_C	1.001	1.00
343_R	346_I	1.000	1.00
459_S	463_I	0.999	1.00
204_R	210_K	0.997	1.00
493_R	497_K	0.996	1.00
350_E	354_K	0.992	1.00
195_E	198_V	0.991	1.00
462_E	466_F	0.991	1.00
525_M	532_A	0.989	1.00
201_G	385_E	0.989	1.00
376_Q	382_Y	0.985	1.00
484_P	490_S	0.983	1.00
463_I	466_F	0.980	1.00
396_N	400_T	0.979	1.00
524_R	531_A	0.977	1.00
451_T	454_I	0.972	1.00
184_D	188_K	0.971	1.00
142_H	292_M	0.969	1.00
440_K	444_N	0.969	1.00
470_L	475_F	0.967	1.00
206_N	209_F	0.964	1.00
412_M	418_I	0.963	1.00
101_L	105_K	0.961	1.00
392_G	397_C	0.959	1.00
365_M	368_Y	0.958	1.00
455_L	467_I	0.956	1.00
375_L	384_G	0.956	1.00
99_E	102_N	0.954	1.00
431_Q	435_G	0.953	1.00
481_G	485_T	0.952	1.00
518_E	522_R	0.952	1.00
350_E	353_E	0.948	1.00
426_K	429_V	0.946	1.00
491_K	495_V	0.943	1.00
203_S	206_N	0.941	1.00
522_R	526_V	0.941	1.00
414_L	418_I	0.940	1.00
456_K	459_S	0.938	1.00
348_Q	351_H	0.936	1.00
479_S	484_P	0.934	1.00
378_F	381_M	0.933	1.00
87_Y	91_T	0.930	1.00
29_V	36_T	0.930	1.00
389_D	392_G	0.927	1.00
210_K	213_K	0.926	1.00
272_Q	281_L	0.926	1.00
94_N	98_Y	0.924	1.00
379_I	382_Y	0.919	1.00
490_S	495_V	0.919	1.00
372_E	380_L	0.917	1.00
429_V	436_S	0.916	1.00
414_L	417_I	0.915	1.00
523_L	531_A	0.912	1.00
379_I	383_F	0.912	1.00
182_V	186_I	0.911	1.00
460_V	463_I	0.911	1.00
180_P	183_H	0.911	1.00
424_F	428_M	0.911	1.00
64_I	119_L	0.911	1.00
373_D	376_Q	0.907	1.00
372_E	376_Q	0.902	1.00
223_E	227_N	0.896	1.00
365_M	370_H	0.893	1.00
54_A	111_L	0.890	1.00
426_K	432_V	0.889	1.00
415_S	418_I	0.888	1.00
491_K	494_N	0.888	1.00
398_T	401_R	0.887	1.00
409_E	412_M	0.885	1.00
87_Y	92_Q	0.883	1.00
359_L	362_L	0.881	1.00
393_Q	396_N	0.880	1.00
335_S	340_M	0.877	1.00
425_G	432_V	0.875	1.00
471_I	476_I	0.869	1.00
363_R	366_V	0.868	1.00
419_R	451_T	0.868	1.00
486_L	489_S	0.867	1.00
32_A	36_T	0.866	1.00
342_Q	352_E	0.864	0.99
479_S	482_T	0.863	0.99
457_H	460_V	0.863	0.99
98_Y	102_N	0.862	0.99
454_I	458_Q	0.860	0.99
378_F	382_Y	0.859	0.99
8_L	11_H	0.857	0.99
376_Q	384_G	0.856	0.99
497_K	501_S	0.856	0.99
426_K	430_A	0.855	0.99
471_I	475_F	0.853	0.99
394_C	400_T	0.852	0.99
454_I	457_H	0.849	0.99
208_T	212_V	0.849	0.99
104_L	131_I	0.848	0.99
225_V	233_G	0.848	0.99
35_N	193_Q	0.847	0.99
343_R	347_E	0.847	0.99
242_E	245_R	0.845	0.99
207_L	211_V	0.844	0.99
205_E	212_V	0.843	0.99
466_F	473_D	0.843	0.99
50_Y	74_Q	0.842	0.99
515_E	519_L	0.841	0.99
465_D	471_I	0.841	0.99
379_I	384_G	0.838	0.99
392_G	396_N	0.837	0.99
337_Q	340_M	0.835	0.99
260_Y	290_F	0.835	0.99
416_C	420_M	0.831	0.99
368_Y	371_T	0.830	0.99
202_F	208_T	0.827	0.99
374_C	379_I	0.827	0.99
248_E	251_K	0.823	0.99
460_V	464_S	0.823	0.99
411_Q	417_I	0.823	0.99
523_L	528_K	0.822	0.99
387_E	390_A	0.822	0.99
135_L	172_M	0.821	0.99
515_E	521_E	0.820	0.99
412_M	419_R	0.819	0.99
248_E	252_R	0.819	0.99
341_V	346_I	0.818	0.99
488_V	491_K	0.818	0.99
514_T	517_D	0.816	0.99
226_Q	255_V	0.814	0.99
514_T	518_E	0.814	0.99
224_Y	301_F	0.813	0.99
446_F	451_T	0.812	0.99
497_K	500_L	0.812	0.99
418_I	422_E	0.811	0.99
490_S	498_G	0.809	0.99
390_A	393_Q	0.809	0.99
428_M	444_N	0.808	0.99
361_K	365_M	0.806	0.99
183_H	187_C	0.803	0.99
486_L	496_L	0.802	0.99
519_L	526_V	0.802	0.99
367_D	371_T	0.800	0.99
411_Q	415_S	0.800	0.99
446_F	450_S	0.800	0.99
102_N	106_E	0.800	0.99
321_A	328_S	0.798	0.99
163_R	191_H	0.797	0.99
433_L	440_K	0.795	0.99
452_Y	457_H	0.793	0.99
467_I	472_S	0.791	0.99
428_M	441_V	0.790	0.99
492_G	498_G	0.788	0.99
239_T	262_G	0.786	0.99
483_F	493_R	0.785	0.99
479_S	483_F	0.785	0.99
411_Q	419_R	0.784	0.99
351_H	355_Q	0.784	0.99
303_L	331_V	0.782	0.99
515_E	530_I	0.781	0.99
400_T	403_A	0.779	0.99
374_C	378_F	0.775	0.99
464_S	470_L	0.774	0.99
218_D	305_A	0.774	0.99
519_L	529_E	0.773	0.99
204_R	213_K	0.770	0.99
488_V	496_L	0.770	0.99
457_H	461_G	0.769	0.99
458_Q	463_I	0.761	0.99
218_D	245_R	0.759	0.99
349_S	352_E	0.758	0.99
456_K	460_V	0.758	0.99
239_T	242_E	0.758	0.99
488_V	494_N	0.757	0.99
194_K	197_T	0.757	0.99
393_Q	401_R	0.757	0.99
395_G	399_D	0.757	0.99
208_T	329_E	0.756	0.99
67_L	292_M	0.755	0.99
524_R	527_R	0.754	0.99
446_F	453_G	0.754	0.99
449_L	452_Y	0.754	0.99
401_R	404_H	0.753	0.99
408_R	418_I	0.753	0.99
29_V	174_L	0.752	0.99
372_E	381_M	0.752	0.99
523_L	526_V	0.751	0.99
496_L	499_E	0.751	0.99
415_S	419_R	0.751	0.99
406_V	466_F	0.750	0.99
357_Q	360_K	0.749	0.99
489_S	496_L	0.748	0.99
517_D	522_R	0.747	0.99
375_L	383_F	0.746	0.99
424_F	432_V	0.745	0.99
162_F	171_I	0.743	0.98
217_K	305_A	0.743	0.98
84_N	108_A	0.739	0.98
484_P	492_G	0.739	0.98
432_V	441_V	0.737	0.98
50_Y	174_L	0.737	0.98
484_P	488_V	0.736	0.98
340_M	343_R	0.735	0.98
521_E	529_E	0.735	0.98
437_K	441_V	0.734	0.98
498_G	502_V	0.733	0.98
518_E	521_E	0.732	0.98
204_R	212_V	0.731	0.98
374_C	380_L	0.730	0.98
489_S	502_V	0.730	0.98
160_I	163_R	0.730	0.98
453_G	470_L	0.729	0.98
182_V	185_D	0.728	0.98
453_G	458_Q	0.728	0.98
519_L	527_R	0.728	0.98
77_A	295_D	0.727	0.98
432_V	437_K	0.725	0.98
15_Y	48_I	0.724	0.98
362_L	366_V	0.722	0.98
231_E	300_R	0.720	0.98
517_D	530_I	0.718	0.98
374_C	377_R	0.716	0.98
469_F	472_S	0.716	0.98
466_F	475_F	0.715	0.98
488_V	495_V	0.715	0.98
247_Y	251_K	0.713	0.98
432_V	435_G	0.713	0.98
524_R	528_K	0.711	0.98
473_D	477_R	0.711	0.98
34_Q	194_K	0.710	0.98
178_A	322_G	0.709	0.98
477_R	480_D	0.704	0.98
406_V	409_E	0.703	0.98
205_E	208_T	0.700	0.98
79_E	86_A	0.700	0.98
243_A	285_V	0.699	0.98
409_E	416_C	0.699	0.98
345_L	348_Q	0.698	0.98
475_F	479_S	0.697	0.98
520_F	526_V	0.696	0.98
334_F	342_Q	0.696	0.98
407_T	411_Q	0.694	0.98
408_R	417_I	0.693	0.98
304_H	318_A	0.693	0.98
72_K	270_K	0.692	0.98
49_C	53_P	0.691	0.98
467_I	471_I	0.691	0.98
474_D	477_R	0.690	0.98
410_A	416_C	0.690	0.98
218_D	222_D	0.690	0.98
473_D	476_I	0.688	0.98
468_E	475_F	0.687	0.97
356_K	365_M	0.686	0.97
408_R	414_L	0.686	0.97
441_V	446_F	0.686	0.97
465_D	469_F	0.686	0.97
203_S	376_Q	0.684	0.97
481_G	484_P	0.684	0.97
464_S	468_E	0.683	0.97
166_H	169_P	0.681	0.97
436_S	440_K	0.681	0.97
467_I	476_I	0.678	0.97
424_F	444_N	0.678	0.97
420_M	432_V	0.678	0.97
446_F	454_I	0.677	0.97
479_S	488_V	0.677	0.97
202_F	211_V	0.676	0.97
135_L	174_L	0.676	0.97
470_L	476_I	0.675	0.97
413_V	419_R	0.673	0.97
526_V	531_A	0.672	0.97
376_Q	379_I	0.670	0.97
471_I	479_S	0.669	0.97
372_E	378_F	0.669	0.97
345_L	355_Q	0.668	0.97
523_L	530_I	0.665	0.97
469_F	474_D	0.663	0.97
376_Q	385_E	0.662	0.97
372_E	382_Y	0.662	0.97
360_K	365_M	0.661	0.97
498_G	501_S	0.661	0.97
78_L	85_A	0.661	0.97
374_C	384_G	0.660	0.97
479_S	485_T	0.660	0.97
475_F	495_V	0.659	0.97
32_A	57_F	0.659	0.97
515_E	518_E	0.658	0.97
451_T	455_L	0.658	0.97
369_C	379_I	0.656	0.97
425_G	435_G	0.656	0.97
75_V	79_E	0.655	0.97
521_E	527_R	0.654	0.97
428_M	436_S	0.653	0.97
358_D	367_D	0.652	0.97
514_T	524_R	0.651	0.97
428_M	435_G	0.650	0.96
224_Y	333_L	0.650	0.96
332_L	335_S	0.649	0.96
424_F	446_F	0.648	0.96
463_I	467_I	0.648	0.96
374_C	381_M	0.647	0.96
142_H	316_Q	0.643	0.96
8_L	12_Y	0.643	0.96
520_F	528_K	0.642	0.96
366_V	371_T	0.642	0.96
450_S	453_G	0.642	0.96
349_S	354_K	0.641	0.96
416_C	451_T	0.639	0.96
257_A	285_V	0.639	0.96
430_A	433_L	0.638	0.96
220_F	223_E	0.636	0.96
516_N	526_V	0.636	0.96
495_V	500_L	0.636	0.96
405_D	410_A	0.635	0.96
361_K	367_D	0.635	0.96
335_S	338_D	0.635	0.96
516_N	522_R	0.634	0.96
92_Q	100_R	0.634	0.96
345_L	352_E	0.633	0.96
519_L	528_K	0.632	0.96
452_Y	462_E	0.631	0.96
478_M	481_G	0.631	0.96
375_L	395_G	0.631	0.96
520_F	529_E	0.629	0.96
492_G	502_V	0.629	0.96
452_Y	456_K	0.628	0.96
267_D	271_E	0.626	0.96
525_M	528_K	0.625	0.96
487_F	490_S	0.624	0.96
517_D	529_E	0.623	0.96
61_T	135_L	0.622	0.96
441_V	444_N	0.622	0.96
455_L	458_Q	0.622	0.96
402_A	405_D	0.620	0.95
503_A	529_E	0.620	0.95
427_T	437_K	0.619	0.95
382_Y	385_E	0.619	0.95
521_E	531_A	0.618	0.95
60_T	134_P	0.616	0.95
485_T	490_S	0.616	0.95
207_L	213_K	0.615	0.95
524_R	529_E	0.613	0.95
518_E	530_I	0.610	0.95
476_I	480_D	0.609	0.95
488_V	498_G	0.608	0.95
515_E	520_F	0.608	0.95
390_A	394_C	0.606	0.95
452_Y	455_L	0.602	0.95
361_K	369_C	0.601	0.95
12_Y	83_I	0.600	0.95
220_F	224_Y	0.597	0.94
459_S	464_S	0.597	0.94
206_N	212_V	0.596	0.94
471_I	486_L	0.593	0.94
304_H	332_L	0.592	0.94
187_C	192_I	0.592	0.94
490_S	496_L	0.590	0.94
476_I	479_S	0.589	0.94
407_T	414_L	0.589	0.94
361_K	379_I	0.587	0.94
479_S	487_F	0.586	0.94
366_V	372_E	0.586	0.94
519_L	524_R	0.585	0.94
205_E	210_K	0.585	0.94
419_R	450_S	0.584	0.94
212_V	220_F	0.584	0.94
232_A	300_R	0.583	0.94
424_F	430_A	0.582	0.94
114_I	124_F	0.582	0.94
212_V	333_L	0.582	0.94
467_I	470_L	0.582	0.94
432_V	446_F	0.582	0.94
480_D	489_S	0.581	0.94
415_S	421_K	0.581	0.94
77_A	80_E	0.579	0.93
420_M	424_F	0.579	0.93
205_E	213_K	0.579	0.93
459_S	466_F	0.578	0.93
466_F	472_S	0.578	0.93
97_I	118_R	0.577	0.93
377_R	384_G	0.576	0.93
67_L	117_E	0.576	0.93
273_Q	296_K	0.575	0.93
485_T	495_V	0.574	0.93
494_N	502_V	0.571	0.93
403_A	406_V	0.568	0.93
433_L	441_V	0.567	0.93
433_L	437_K	0.566	0.93
420_M	433_L	0.565	0.93
487_F	491_K	0.564	0.93
391_C	397_C	0.564	0.93
347_E	351_H	0.562	0.92
429_V	438_N	0.560	0.92
453_G	463_I	0.558	0.92
515_E	528_K	0.558	0.92
457_H	463_I	0.558	0.92
35_N	162_F	0.557	0.92
518_E	529_E	0.557	0.92
422_E	425_G	0.556	0.92
370_H	379_I	0.556	0.92
449_L	454_I	0.555	0.92
407_T	415_S	0.554	0.92
193_Q	196_N	0.554	0.92
458_Q	471_I	0.553	0.92
444_N	447_S	0.550	0.92
359_L	363_R	0.549	0.92
489_S	494_N	0.548	0.91
491_K	496_L	0.548	0.91
489_S	500_L	0.548	0.91
320_R	323_R	0.548	0.91
428_M	437_K	0.546	0.91
264_L	272_Q	0.545	0.91
461_G	465_D	0.545	0.91
200_T	204_R	0.544	0.91
369_C	380_L	0.543	0.91
411_Q	420_M	0.542	0.91
421_K	425_G	0.542	0.91
514_T	521_E	0.542	0.91
359_L	368_Y	0.541	0.91
425_G	437_K	0.541	0.91
434_A	463_I	0.540	0.91
408_R	419_R	0.539	0.91
333_L	336_P	0.539	0.91
486_L	497_K	0.538	0.91
465_D	468_E	0.538	0.91
429_V	434_A	0.537	0.91
359_L	370_H	0.535	0.91
412_M	416_C	0.535	0.91
202_F	213_K	0.534	0.90
520_F	525_M	0.534	0.90
525_M	529_E	0.534	0.90
286_A	290_F	0.533	0.90
268_V	271_E	0.533	0.90
411_Q	418_I	0.532	0.90
374_C	385_E	0.532	0.90
522_R	529_E	0.531	0.90
368_Y	372_E	0.531	0.90
21_G	24_E	0.531	0.90
418_I	488_V	0.530	0.90
27_R	30_T	0.530	0.90
201_G	204_R	0.529	0.90
472_S	475_F	0.529	0.90
357_Q	370_H	0.529	0.90
477_R	489_S	0.529	0.90
390_A	397_C	0.529	0.90
517_D	524_R	0.527	0.90
420_M	429_V	0.527	0.90
490_S	497_K	0.526	0.90
454_I	463_I	0.526	0.90
462_E	467_I	0.526	0.90
375_L	381_M	0.526	0.90
76_D	80_E	0.526	0.90
477_R	481_G	0.525	0.90
364_Q	367_D	0.525	0.90
447_S	450_S	0.523	0.90
518_E	525_M	0.523	0.90
407_T	416_C	0.523	0.90
50_Y	53_P	0.523	0.90
472_S	477_R	0.521	0.89
452_Y	463_I	0.521	0.89
375_L	386_K	0.521	0.89
431_Q	434_A	0.520	0.89
357_Q	366_V	0.520	0.89
238_A	306_Q	0.519	0.89
377_R	383_F	0.518	0.89
374_C	394_C	0.518	0.89
455_L	475_F	0.518	0.89
358_D	366_V	0.518	0.89
486_L	495_V	0.517	0.89
449_L	455_L	0.516	0.89
160_I	164_E	0.516	0.89
428_M	433_L	0.514	0.89
466_F	476_I	0.514	0.89
431_Q	436_S	0.513	0.89
387_E	392_G	0.513	0.89
67_L	73_D	0.512	0.89
517_D	528_K	0.511	0.88
450_S	459_S	0.511	0.88
121_S	124_F	0.510	0.88
54_A	135_L	0.510	0.88
462_E	472_S	0.510	0.88
161_L	166_H	0.510	0.88
381_M	386_K	0.509	0.88
469_F	477_R	0.508	0.88
221_I	235_V	0.506	0.88
524_R	532_A	0.504	0.88
460_V	465_D	0.504	0.88
301_F	331_V	0.503	0.88
463_I	470_L	0.503	0.88
451_T	459_S	0.503	0.88
517_D	527_R	0.502	0.88
378_F	385_E	0.501	0.87
448_D	452_Y	0.501	0.87
455_L	466_F	0.501	0.87
187_C	193_Q	0.501	0.87
361_K	368_Y	0.501	0.87
520_F	527_R	0.500	0.87

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1oywA	1	0.8596	100	0.291	Contact Map
4q48A	1	0.8443	100	0.305	Contact Map
4o3mA	1	0.9577	100	0.308	Contact Map
2v1xA	1	0.8308	100	0.343	Contact Map
4pxaA	1	0.6041	100	0.388	Contact Map
4ljyA	1	0.6159	100	0.397	Contact Map
4nhoA	1	0.5905	100	0.398	Contact Map
2db3A	1	0.5939	100	0.4	Contact Map
4d25A	1	0.5922	100	0.411	Contact Map
4c9bA	1	0.5939	100	0.413	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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