BCEB - BACSU - GREMLIN Contacts

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BCEB - Bacitracin export permease protein BceB

UniProt:	O34741	Sequences: MNINQLILRNLKKNLRNYYLYVFALIFSVALYFAFVTLQYDPAINEVKASIKGAAAIKTASILLVAVVAIFILYANTIFIKRRSKEIGLFQLIGMTKHKIFRILSAENVMLYFGSLAIGVAAGFSISKLVLMILFKIVDVKADAKLHFSEQALVQTVIVFCGIYLLIMIMNYTFIKKQSILSLFKVTSSTEDKVKKISFFQMLIGALGIVLILTGYYVSSELFGGKFKTINELFVAMSFILGSVIIGTFLFYKGSVTFISNIIRKSKGGYLNISEVLSLSSIMFRMKSNALLLTIITTVSALAIGLLSLAYISYYSSEKTAEQNVAADFSFMNEKDAKLFENKLRESNISFVKKATPVLQANVDIANIMDGTPKEMQGDPGNMQLAVVSDKDVKGVDVAAGEAVFSGYTDLLQKIMVFKDSGVIKVKSKHETQPLKYKGLREEFLVSYTFTSGGMPAVIVDDSLFKQLDKDKDPRIQLAQSTFIGVNVKHDDQMEKANELFQQVNKKNEHLSRLDTSAAQKSLFGMVMFIVGFLGLTFLITSGCILYFKQMGESEDEKPSYTILRKLGFTQGDLIKGIRIKQMYNFGIPLVVGLFHSYFAVQSGWFLFGSEVWAPMIMVMVLYTALYSIFGFLSVLYYKKVIKSSL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	646 (609)
Sequences:	2060 (1865)
Seq/√Len:	75.6

ECOLI - YBBP
BACSU - BCEB YVCS YXDM

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
398_V	402_E	8.439	1.00
398_V	401_G	5.840	1.00
391_K	394_K	5.543	1.00
211_L	243_S	4.834	1.00
148_F	153_L	4.448	1.00
382_N	390_D	4.416	1.00
398_V	406_S	4.076	1.00
383_M	390_D	3.834	1.00
380_P	383_M	3.814	1.00
402_E	406_S	3.665	1.00
383_M	386_A	3.534	1.00
154_V	158_I	3.480	1.00
275_E	580_I	3.471	1.00
390_D	394_K	3.424	1.00
216_Y	596_H	3.346	1.00
617_I	621_V	3.177	1.00
459_I	462_D	3.099	1.00
233_L	236_A	3.045	1.00
380_P	390_D	3.004	1.00
387_V	394_K	2.980	1.00
397_D	402_E	2.930	1.00
216_Y	219_S	2.903	1.00
424_I	428_S	2.849	1.00
220_S	599_F	2.845	1.00
387_V	390_D	2.834	1.00
387_V	391_K	2.809	1.00
262_I	266_S	2.757	1.00
213_L	217_Y	2.754	1.00
461_D	464_L	2.735	1.00
248_T	596_H	2.716	1.00
76_N	171_N	2.698	1.00
399_A	402_E	2.679	1.00
33_F	37_T	2.539	1.00
349_I	352_V	2.492	1.00
340_F	347_S	2.488	1.00
596_H	600_A	2.484	1.00
388_V	391_K	2.481	1.00
83_R	107_E	2.416	1.00
401_G	406_S	2.411	1.00
397_D	401_G	2.357	1.00
382_N	387_V	2.324	1.00
251_F	592_V	2.296	1.00
244_V	600_A	2.295	1.00
382_N	386_A	2.283	1.00
493_Q	496_K	2.247	1.00
382_N	391_K	2.242	1.00
382_N	389_S	2.224	1.00
388_V	394_K	2.208	1.00
216_Y	248_T	2.190	1.00
627_Y	634_S	2.183	1.00
387_V	392_D	2.179	1.00
382_N	388_V	2.159	1.00
381_G	384_Q	2.149	1.00
215_G	243_S	2.130	1.00
293_L	299_V	2.104	1.00
217_Y	221_E	2.069	1.00
343_K	347_S	2.058	1.00
340_F	343_K	2.032	1.00
22_V	115_S	2.023	1.00
398_V	403_A	2.015	1.00
210_V	214_T	2.004	1.00
381_G	390_D	1.990	1.00
185_K	188_S	1.986	1.00
575_I	639_K	1.977	1.00
403_A	406_S	1.954	1.00
460_V	464_L	1.950	1.00
252_Y	297_T	1.949	1.00
215_G	247_G	1.911	1.00
10_N	24_A	1.908	1.00
301_A	305_G	1.891	1.00
342_N	346_E	1.885	1.00
496_K	499_E	1.876	1.00
348_N	351_F	1.869	1.00
398_V	404_V	1.868	1.00
338_K	342_N	1.859	1.00
124_F	148_F	1.851	1.00
21_Y	108_N	1.848	1.00
384_Q	387_V	1.846	1.00
383_M	388_V	1.836	1.00
562_T	566_K	1.804	1.00
591_V	595_F	1.799	1.00
26_I	118_I	1.768	1.00
579_R	631_G	1.763	1.00
391_K	395_G	1.753	1.00
343_K	346_E	1.745	1.00
205_G	208_G	1.729	1.00
32_Y	156_T	1.720	1.00
216_Y	220_S	1.719	1.00
386_A	390_D	1.719	1.00
379_D	383_M	1.716	1.00
277_L	569_F	1.692	1.00
307_L	535_G	1.687	1.00
322_E	513_R	1.686	1.00
482_T	486_V	1.677	1.00
242_G	246_I	1.674	1.00
173_T	177_K	1.665	1.00
84_S	186_V	1.664	1.00
31_L	34_A	1.658	1.00
182_S	189_S	1.653	1.00
383_M	389_S	1.647	1.00
386_A	389_S	1.640	1.00
30_A	122_A	1.633	1.00
380_P	386_A	1.624	1.00
217_Y	220_S	1.621	1.00
156_T	183_L	1.621	1.00
328_D	513_R	1.609	1.00
546_L	585_N	1.608	1.00
215_G	244_V	1.605	1.00
549_K	553_E	1.604	1.00
440_L	446_V	1.602	1.00
483_F	490_H	1.598	0.99
218_V	243_S	1.598	0.99
129_L	132_M	1.598	0.99
29_V	32_Y	1.590	0.99
483_F	488_V	1.585	0.99
302_L	305_G	1.583	0.99
398_V	407_G	1.583	0.99
420_D	424_I	1.577	0.99
341_E	345_R	1.573	0.99
579_R	635_V	1.565	0.99
67_V	71_F	1.559	0.99
425_K	434_P	1.529	0.99
497_A	504_V	1.517	0.99
389_S	394_K	1.516	0.99
219_S	600_A	1.513	0.99
549_K	585_N	1.512	0.99
121_A	125_S	1.512	0.99
301_A	593_G	1.510	0.99
150_E	154_V	1.504	0.99
78_I	627_Y	1.498	0.99
360_Q	363_V	1.493	0.99
386_A	391_K	1.492	0.99
594_L	620_M	1.486	0.99
215_G	219_S	1.482	0.99
328_D	331_F	1.472	0.99
635_V	638_Y	1.449	0.99
490_H	493_Q	1.447	0.99
570_T	573_D	1.444	0.99
78_I	551_M	1.442	0.99
231_N	235_V	1.434	0.99
396_V	404_V	1.430	0.99
392_D	395_G	1.427	0.99
576_K	580_I	1.420	0.99
248_T	600_A	1.419	0.99
281_S	564_L	1.418	0.99
277_L	281_S	1.418	0.99
274_S	281_S	1.410	0.99
405_F	408_Y	1.406	0.99
339_L	342_N	1.405	0.99
586_F	589_P	1.397	0.99
87_I	104_L	1.393	0.99
128_K	132_M	1.383	0.99
191_E	288_S	1.382	0.99
179_S	182_S	1.371	0.98
400_A	463_S	1.370	0.98
425_K	428_S	1.367	0.98
383_M	391_K	1.366	0.98
29_V	116_L	1.364	0.98
262_I	265_K	1.363	0.98
383_M	387_V	1.358	0.98
257_T	260_S	1.350	0.98
9_R	13_K	1.348	0.98
299_V	303_A	1.335	0.98
204_I	253_K	1.334	0.98
116_L	157_V	1.330	0.98
216_Y	252_Y	1.324	0.98
402_E	436_K	1.322	0.98
294_T	299_V	1.318	0.98
229_T	236_A	1.313	0.98
373_P	379_D	1.307	0.98
399_A	406_S	1.306	0.98
32_Y	65_V	1.303	0.98
498_N	508_N	1.302	0.98
233_L	237_M	1.292	0.98
98_H	102_R	1.290	0.98
463_S	466_K	1.285	0.98
380_P	385_L	1.281	0.98
379_D	382_N	1.279	0.98
124_F	153_L	1.271	0.97
401_G	404_V	1.264	0.97
634_S	641_V	1.262	0.97
252_Y	596_H	1.261	0.97
248_T	252_Y	1.260	0.97
96_T	570_T	1.257	0.97
84_S	174_F	1.255	0.97
391_K	396_V	1.255	0.97
388_V	392_D	1.243	0.97
194_V	284_F	1.237	0.97
305_G	604_G	1.233	0.97
424_I	427_K	1.233	0.97
212_I	599_F	1.232	0.97
76_N	550_Q	1.232	0.97
280_S	284_F	1.228	0.97
386_A	394_K	1.225	0.97
377_Q	383_M	1.223	0.97
435_L	438_K	1.222	0.97
302_L	306_L	1.217	0.97
389_S	395_G	1.214	0.97
377_Q	380_P	1.212	0.97
67_V	75_A	1.211	0.97
244_V	596_H	1.211	0.97
512_S	515_D	1.211	0.97
33_F	124_F	1.207	0.96
554_S	641_V	1.202	0.96
78_I	634_S	1.194	0.96
78_I	552_G	1.188	0.96
216_Y	600_A	1.186	0.96
390_D	395_G	1.178	0.96
134_L	529_F	1.178	0.96
107_E	123_G	1.175	0.96
541_T	546_L	1.174	0.96
91_Q	100_I	1.174	0.96
563_I	566_K	1.174	0.96
599_F	602_Q	1.171	0.96
7_I	11_L	1.167	0.96
139_D	521_K	1.161	0.96
631_G	635_V	1.161	0.96
96_T	99_K	1.160	0.96
32_Y	36_V	1.156	0.95
193_K	261_N	1.156	0.95
26_I	122_A	1.154	0.95
74_Y	545_I	1.153	0.95
549_K	557_E	1.151	0.95
350_S	460_V	1.150	0.95
89_L	92_L	1.141	0.95
86_E	90_F	1.138	0.95
205_G	255_S	1.134	0.95
485_G	488_V	1.130	0.95
380_P	389_S	1.130	0.95
383_M	394_K	1.129	0.95
358_V	365_I	1.128	0.95
112_Y	168_M	1.120	0.95
71_F	79_F	1.115	0.94
297_T	301_A	1.115	0.94
381_G	391_K	1.113	0.94
380_P	387_V	1.113	0.94
207_L	250_L	1.111	0.94
21_Y	115_S	1.107	0.94
244_V	248_T	1.106	0.94
34_A	130_V	1.105	0.94
557_E	581_K	1.105	0.94
554_S	638_Y	1.101	0.94
558_K	562_T	1.101	0.94
397_D	400_A	1.099	0.94
219_S	596_H	1.098	0.94
565_R	574_L	1.097	0.94
319_K	322_E	1.096	0.94
101_F	172_Y	1.093	0.94
404_V	407_G	1.090	0.94
206_A	210_V	1.085	0.94
544_C	548_F	1.082	0.94
635_V	639_K	1.081	0.94
529_F	549_K	1.080	0.93
614_A	618_M	1.076	0.93
456_P	461_D	1.075	0.93
291_L	306_L	1.071	0.93
247_G	251_F	1.068	0.93
540_I	599_F	1.068	0.93
550_Q	627_Y	1.068	0.93
18_Y	35_F	1.067	0.93
369_M	373_P	1.066	0.93
387_V	468_L	1.066	0.93
400_A	461_D	1.063	0.93
329_F	512_S	1.060	0.93
344_L	347_S	1.060	0.93
108_N	171_N	1.057	0.93
208_G	247_G	1.052	0.93
36_V	61_S	1.046	0.92
78_I	90_F	1.041	0.92
372_T	378_G	1.040	0.92
234_F	237_M	1.036	0.92
413_Q	419_K	1.036	0.92
578_I	582_Q	1.035	0.92
229_T	232_E	1.035	0.92
380_P	391_K	1.033	0.92
420_D	423_V	1.030	0.92
211_L	246_I	1.030	0.92
305_G	600_A	1.028	0.92
398_V	408_Y	1.024	0.92
488_V	493_Q	1.022	0.91
161_C	165_L	1.022	0.91
403_A	407_G	1.018	0.91
299_V	542_S	1.014	0.91
587_G	594_L	1.013	0.91
33_F	123_G	1.012	0.91
423_V	434_P	1.012	0.91
120_V	153_L	1.010	0.91
21_Y	24_A	1.008	0.91
628_S	632_F	1.004	0.91
377_Q	389_S	1.001	0.91
357_P	361_A	1.001	0.91
578_I	638_Y	0.998	0.90
71_F	548_F	0.997	0.90
377_Q	382_N	0.994	0.90
602_Q	606_F	0.994	0.90
201_Q	253_K	0.993	0.90
237_M	241_L	0.991	0.90
515_D	519_A	0.990	0.90
433_Q	467_Q	0.989	0.90
212_I	247_G	0.988	0.90
342_N	345_R	0.987	0.90
214_T	218_V	0.986	0.90
269_G	275_E	0.986	0.90
382_N	394_K	0.982	0.90
309_L	313_S	0.981	0.90
495_E	498_N	0.980	0.90
578_I	639_K	0.978	0.90
318_E	322_E	0.976	0.89
17_N	20_L	0.972	0.89
374_K	378_G	0.963	0.89
129_L	153_L	0.962	0.89
117_A	366_A	0.961	0.89
160_F	175_I	0.959	0.89
230_I	237_M	0.953	0.88
389_S	396_V	0.950	0.88
24_A	71_F	0.946	0.88
116_L	160_F	0.943	0.88
148_F	569_F	0.941	0.88
285_R	288_S	0.938	0.88
401_G	405_F	0.937	0.87
25_L	68_V	0.934	0.87
433_Q	437_Y	0.932	0.87
6_L	90_F	0.931	0.87
352_V	355_A	0.929	0.87
627_Y	641_V	0.927	0.87
415_I	418_F	0.925	0.87
90_F	294_T	0.920	0.87
122_A	505_N	0.918	0.86
261_N	265_K	0.918	0.86
533_F	537_T	0.916	0.86
64_L	534_L	0.915	0.86
33_F	156_T	0.915	0.86
74_Y	589_P	0.914	0.86
77_T	84_S	0.914	0.86
454_G	457_A	0.913	0.86
290_A	301_A	0.911	0.86
377_Q	381_G	0.911	0.86
613_W	617_I	0.911	0.86
76_N	586_F	0.906	0.86
216_Y	599_F	0.899	0.85
435_L	460_V	0.899	0.85
455_M	459_I	0.895	0.85
401_G	464_L	0.895	0.85
10_N	14_N	0.893	0.85
505_N	509_E	0.892	0.85
334_E	337_A	0.889	0.85
484_I	488_V	0.889	0.85
157_V	337_A	0.887	0.84
293_L	300_S	0.885	0.84
368_I	371_G	0.882	0.84
229_T	233_L	0.881	0.84
132_M	136_K	0.880	0.84
377_Q	386_A	0.879	0.84
285_R	292_L	0.879	0.84
14_N	86_E	0.878	0.84
134_L	549_K	0.877	0.84
499_E	503_Q	0.876	0.84
207_L	401_G	0.876	0.84
319_K	323_Q	0.874	0.84
494_M	498_N	0.873	0.83
497_A	500_L	0.873	0.83
359_L	362_N	0.872	0.83
382_N	385_L	0.872	0.83
76_N	252_Y	0.870	0.83
73_L	170_M	0.869	0.83
381_G	386_A	0.867	0.83
428_S	435_L	0.867	0.83
201_Q	254_G	0.866	0.83
513_R	516_T	0.866	0.83
352_V	356_T	0.863	0.83
56_A	62_I	0.862	0.83
382_N	392_D	0.859	0.82
458_V	461_D	0.859	0.82
437_Y	440_L	0.858	0.82
423_V	427_K	0.858	0.82
80_I	171_N	0.855	0.82
74_Y	586_F	0.855	0.82
212_I	219_S	0.853	0.82
551_M	561_Y	0.851	0.82
160_F	163_I	0.850	0.82
547_Y	557_E	0.849	0.82
249_F	253_K	0.847	0.82
578_I	597_S	0.844	0.81
260_S	282_I	0.843	0.81
482_T	485_G	0.840	0.81
41_D	131_L	0.838	0.81
400_A	406_S	0.838	0.81
397_D	403_A	0.838	0.81
58_K	62_I	0.836	0.81
194_V	257_T	0.835	0.81
235_V	342_N	0.835	0.81
67_V	537_T	0.835	0.81
270_Y	276_V	0.833	0.81
601_V	605_W	0.833	0.81
52_K	56_A	0.833	0.81
389_S	392_D	0.832	0.80
378_G	383_M	0.828	0.80
368_I	373_P	0.828	0.80
387_V	395_G	0.827	0.80
301_A	596_H	0.825	0.80
437_Y	441_R	0.823	0.80
7_I	10_N	0.822	0.80
363_V	366_A	0.822	0.80
38_L	534_L	0.821	0.80
515_D	518_A	0.818	0.79
629_I	633_L	0.816	0.79
64_L	285_R	0.815	0.79
370_D	373_P	0.814	0.79
380_P	384_Q	0.814	0.79
285_R	289_N	0.814	0.79
372_T	379_D	0.813	0.79
280_S	293_L	0.811	0.79
299_V	548_F	0.810	0.79
245_I	298_T	0.810	0.79
169_I	173_T	0.809	0.79
514_L	517_S	0.808	0.78
13_K	561_Y	0.807	0.78
91_Q	96_T	0.805	0.78
11_L	22_V	0.803	0.78
255_S	630_F	0.803	0.78
358_V	364_D	0.801	0.78
371_G	378_G	0.801	0.78
534_L	538_F	0.799	0.78
79_F	547_Y	0.798	0.78
487_N	490_H	0.795	0.77
301_A	623_Y	0.793	0.77
264_R	280_S	0.792	0.77
384_Q	388_V	0.792	0.77
65_V	159_V	0.791	0.77
86_E	581_K	0.790	0.77
534_L	539_L	0.790	0.77
347_S	489_K	0.788	0.77
336_D	365_I	0.788	0.77
125_S	129_L	0.787	0.77
529_F	548_F	0.787	0.77
17_N	24_A	0.787	0.77
347_S	500_L	0.786	0.77
623_Y	627_Y	0.785	0.76
230_I	234_F	0.785	0.76
32_Y	41_D	0.784	0.76
26_I	30_A	0.783	0.76
375_E	379_D	0.783	0.76
349_I	357_P	0.782	0.76
544_C	557_E	0.779	0.76
378_G	390_D	0.779	0.76
498_N	502_Q	0.779	0.76
22_V	42_P	0.779	0.76
211_L	215_G	0.779	0.76
356_T	424_I	0.778	0.76
42_P	147_H	0.778	0.76
503_Q	507_K	0.777	0.76
89_L	561_Y	0.776	0.76
122_A	336_D	0.775	0.76
390_D	401_G	0.774	0.75
380_P	394_K	0.774	0.75
304_I	542_S	0.773	0.75
32_Y	39_Q	0.772	0.75
401_G	458_V	0.772	0.75
204_I	250_L	0.770	0.75
165_L	169_I	0.768	0.75
127_S	281_S	0.767	0.75
420_D	428_S	0.766	0.75
67_V	541_T	0.765	0.75
133_I	137_I	0.765	0.75
95_M	550_Q	0.765	0.75
529_F	627_Y	0.765	0.75
84_S	146_L	0.764	0.74
384_Q	389_S	0.764	0.74
214_T	243_S	0.763	0.74
316_S	319_K	0.760	0.74
391_K	462_D	0.760	0.74
630_F	634_S	0.759	0.74
550_Q	581_K	0.758	0.74
260_S	283_M	0.757	0.74
281_S	630_F	0.756	0.74
434_P	437_Y	0.756	0.74
547_Y	589_P	0.754	0.74
525_G	529_F	0.753	0.73
548_F	638_Y	0.753	0.73
277_L	329_F	0.752	0.73
158_I	438_K	0.751	0.73
468_L	472_K	0.751	0.73
621_V	625_A	0.750	0.73
399_A	576_K	0.749	0.73
277_L	280_S	0.749	0.73
418_F	421_S	0.748	0.73
523_L	526_M	0.747	0.73
65_V	108_N	0.746	0.73
14_N	18_Y	0.746	0.73
531_V	557_E	0.745	0.73
300_S	593_G	0.745	0.73
12_K	15_L	0.744	0.73
376_M	379_D	0.744	0.73
86_E	586_F	0.743	0.72
243_S	247_G	0.742	0.72
244_V	285_R	0.741	0.72
399_A	405_F	0.740	0.72
362_N	365_I	0.739	0.72
506_K	509_E	0.739	0.72
270_Y	300_S	0.738	0.72
162_G	336_D	0.737	0.72
100_I	255_S	0.737	0.72
21_Y	32_Y	0.737	0.72
627_Y	635_V	0.737	0.72
111_L	179_S	0.736	0.72
462_D	466_K	0.736	0.72
18_Y	21_Y	0.735	0.72
280_S	547_Y	0.734	0.71
500_L	505_N	0.733	0.71
439_G	492_D	0.732	0.71
24_A	533_F	0.732	0.71
300_S	623_Y	0.731	0.71
397_D	407_G	0.729	0.71
443_E	447_S	0.727	0.71
538_F	563_I	0.726	0.71
284_F	288_S	0.725	0.71
83_R	123_G	0.724	0.70
35_F	111_L	0.724	0.70
216_Y	244_V	0.723	0.70
6_L	9_R	0.723	0.70
504_V	507_K	0.722	0.70
285_R	307_L	0.720	0.70
280_S	529_F	0.720	0.70
346_E	425_K	0.718	0.70
372_T	376_M	0.718	0.70
531_V	596_H	0.717	0.70
9_R	21_Y	0.716	0.70
153_L	499_E	0.716	0.70
483_F	486_V	0.712	0.69
10_N	107_E	0.711	0.69
557_E	577_G	0.711	0.69
99_K	130_V	0.711	0.69
6_L	185_K	0.711	0.69
71_F	544_C	0.710	0.69
90_F	545_I	0.710	0.69
297_T	302_L	0.708	0.69
15_L	68_V	0.707	0.69
341_E	594_L	0.706	0.69
541_T	547_Y	0.706	0.69
157_V	421_S	0.705	0.68
17_N	537_T	0.703	0.68
400_A	404_V	0.702	0.68
460_V	465_F	0.698	0.68
404_V	408_Y	0.697	0.68
548_F	623_Y	0.697	0.68
79_F	544_C	0.696	0.67
368_I	375_E	0.696	0.67
135_F	577_G	0.694	0.67
3_I	95_M	0.694	0.67
81_K	553_E	0.693	0.67
168_M	544_C	0.693	0.67
29_V	119_G	0.693	0.67
513_R	517_S	0.693	0.67
285_R	290_A	0.692	0.67
75_A	561_Y	0.691	0.67
412_L	416_M	0.689	0.67
310_A	528_M	0.688	0.67
631_G	634_S	0.687	0.66
247_G	596_H	0.687	0.66
433_Q	436_K	0.686	0.66
380_P	462_D	0.686	0.66
380_P	388_V	0.684	0.66
561_Y	577_G	0.683	0.66
202_M	205_G	0.681	0.66
5_Q	9_R	0.680	0.66
383_M	396_V	0.678	0.65
37_T	76_N	0.677	0.65
34_A	174_F	0.675	0.65
501_F	504_V	0.675	0.65
527_V	591_V	0.675	0.65
112_Y	164_Y	0.675	0.65
3_I	11_L	0.673	0.65
486_V	493_Q	0.672	0.65
41_D	134_L	0.672	0.65
99_K	102_R	0.671	0.65
370_D	375_E	0.671	0.65
245_I	248_T	0.668	0.64
3_I	7_I	0.668	0.64
557_E	638_Y	0.667	0.64
340_F	345_R	0.666	0.64
350_S	353_K	0.666	0.64
377_Q	396_V	0.665	0.64
304_I	619_V	0.664	0.64
112_Y	160_F	0.663	0.64
370_D	377_Q	0.662	0.64
314_Y	525_G	0.662	0.64
152_A	529_F	0.659	0.63
230_I	459_I	0.659	0.63
74_Y	183_L	0.659	0.63
67_V	79_F	0.658	0.63
13_K	24_A	0.657	0.63
565_R	571_Q	0.657	0.63
531_V	548_F	0.657	0.63
210_V	395_G	0.656	0.63
20_L	25_L	0.656	0.63
24_A	284_F	0.653	0.63
296_I	310_A	0.653	0.63
348_N	352_V	0.652	0.62
42_P	46_E	0.652	0.62
317_S	321_A	0.652	0.62
227_F	236_A	0.650	0.62
123_G	568_G	0.648	0.62
338_K	463_S	0.647	0.62
109_V	113_F	0.646	0.62
112_Y	537_T	0.645	0.62
41_D	144_A	0.645	0.62
130_V	517_S	0.645	0.62
126_I	536_L	0.645	0.62
569_F	585_N	0.645	0.62
359_L	366_A	0.643	0.61
65_V	163_I	0.642	0.61
25_L	32_Y	0.641	0.61
424_I	433_Q	0.640	0.61
260_S	585_N	0.640	0.61
552_G	634_S	0.640	0.61
548_F	557_E	0.640	0.61
401_G	407_G	0.639	0.61
15_L	35_F	0.639	0.61
301_A	544_C	0.636	0.60
297_T	303_A	0.635	0.60
422_G	437_Y	0.635	0.60
90_F	627_Y	0.635	0.60
594_L	598_Y	0.635	0.60
212_I	600_A	0.635	0.60
71_F	549_K	0.634	0.60
379_D	621_V	0.634	0.60
71_F	547_Y	0.633	0.60
21_Y	112_Y	0.633	0.60
358_V	361_A	0.632	0.60
550_Q	553_E	0.632	0.60
24_A	544_C	0.632	0.60
533_F	544_C	0.631	0.60
289_N	581_K	0.631	0.60
355_A	359_L	0.630	0.60
28_S	565_R	0.630	0.60
566_K	589_P	0.629	0.60
181_L	277_L	0.629	0.60
34_A	608_F	0.628	0.60
292_L	295_I	0.627	0.59
39_Q	44_I	0.626	0.59
305_G	534_L	0.626	0.59
25_L	75_A	0.626	0.59
314_Y	318_E	0.626	0.59
33_F	60_A	0.626	0.59
68_V	163_I	0.625	0.59
535_G	560_S	0.624	0.59
381_G	387_V	0.621	0.59
3_I	14_N	0.620	0.59
171_N	254_G	0.620	0.59
21_Y	131_L	0.619	0.58
219_S	244_V	0.619	0.58
275_E	299_V	0.619	0.58
378_G	382_N	0.618	0.58
209_I	500_L	0.617	0.58
370_D	618_M	0.617	0.58
540_I	588_I	0.616	0.58
71_F	256_V	0.616	0.58
193_K	200_F	0.616	0.58
518_A	522_S	0.616	0.58
185_K	189_S	0.614	0.58
57_I	530_I	0.614	0.58
25_L	164_Y	0.613	0.58
221_E	503_Q	0.613	0.58
581_K	590_L	0.612	0.58
371_G	377_Q	0.612	0.58
280_S	585_N	0.612	0.58
78_I	82_R	0.612	0.58
21_Y	25_L	0.611	0.57
14_N	547_Y	0.611	0.57
152_A	156_T	0.611	0.57
279_L	546_L	0.610	0.57
113_F	117_A	0.610	0.57
48_K	51_I	0.610	0.57
359_L	367_N	0.609	0.57
360_Q	366_A	0.609	0.57
536_L	605_W	0.607	0.57
428_S	433_Q	0.606	0.57
271_L	535_G	0.606	0.57
358_V	362_N	0.604	0.57
144_A	593_G	0.603	0.56
93_I	281_S	0.603	0.56
533_F	547_Y	0.602	0.56
150_E	624_T	0.600	0.56
210_V	398_V	0.600	0.56
439_G	454_G	0.599	0.56
283_M	588_I	0.599	0.56
397_D	440_L	0.599	0.56
30_A	546_L	0.599	0.56
486_V	491_D	0.598	0.56
344_L	400_A	0.597	0.56
421_S	511_L	0.597	0.56
117_A	618_M	0.596	0.56
463_S	467_Q	0.596	0.56
204_I	208_G	0.596	0.56
4_N	8_L	0.594	0.55
36_V	40_Y	0.593	0.55
210_V	400_A	0.592	0.55
368_I	376_M	0.592	0.55
230_I	233_L	0.591	0.55
212_I	216_Y	0.591	0.55
352_V	359_L	0.590	0.55
52_K	55_A	0.590	0.55
162_G	346_E	0.589	0.55
41_D	71_F	0.589	0.55
8_L	110_M	0.588	0.55
24_A	30_A	0.588	0.55
167_I	300_S	0.588	0.55
231_N	234_F	0.587	0.54
364_D	503_Q	0.587	0.54
300_S	596_H	0.587	0.54
339_L	396_V	0.587	0.54
175_I	312_I	0.586	0.54
302_L	546_L	0.586	0.54
281_S	581_K	0.586	0.54
336_D	341_E	0.585	0.54
9_R	27_F	0.585	0.54
615_P	619_V	0.584	0.54
553_E	557_E	0.584	0.54
338_K	397_D	0.584	0.54
336_D	625_A	0.582	0.54
229_T	237_M	0.582	0.54
403_A	435_L	0.582	0.54
20_L	544_C	0.582	0.54
66_A	553_E	0.580	0.54
581_K	586_F	0.579	0.53
299_V	538_F	0.579	0.53
265_K	606_F	0.578	0.53
210_V	377_Q	0.578	0.53
9_R	12_K	0.577	0.53
17_N	25_L	0.577	0.53
114_G	209_I	0.576	0.53
14_N	17_N	0.576	0.53
37_T	131_L	0.575	0.53
535_G	586_F	0.575	0.53
113_F	397_D	0.575	0.53
113_F	346_E	0.575	0.53
287_K	301_A	0.574	0.53
230_I	404_V	0.574	0.53
269_G	272_N	0.573	0.53
555_E	641_V	0.572	0.53
165_L	413_Q	0.572	0.53
116_L	129_L	0.572	0.53
193_K	264_R	0.572	0.53
394_K	399_A	0.572	0.53
127_S	561_Y	0.571	0.52
517_S	540_I	0.571	0.52
339_L	349_I	0.571	0.52
154_V	622_L	0.570	0.52
33_F	120_V	0.570	0.52
280_S	557_E	0.570	0.52
214_T	220_S	0.569	0.52
273_I	276_V	0.569	0.52
550_Q	554_S	0.567	0.52
541_T	597_S	0.567	0.52
373_P	377_Q	0.566	0.52
12_K	114_G	0.566	0.52
259_I	446_V	0.566	0.52
28_S	87_I	0.566	0.52
281_S	560_S	0.565	0.52
267_K	271_L	0.564	0.52
484_I	490_H	0.564	0.52
293_L	296_I	0.564	0.52
421_S	428_S	0.564	0.52
170_M	173_T	0.563	0.51
551_M	627_Y	0.563	0.51
360_Q	367_N	0.563	0.51
80_I	103_I	0.563	0.51
130_V	458_V	0.562	0.51
150_E	463_S	0.561	0.51
102_R	106_A	0.560	0.51
286_M	290_A	0.559	0.51
636_L	640_K	0.559	0.51
516_T	519_A	0.558	0.51
546_L	630_F	0.558	0.51
79_F	541_T	0.557	0.51
193_K	281_S	0.557	0.51
90_F	535_G	0.556	0.51
491_D	494_M	0.555	0.50
457_A	462_D	0.555	0.50
71_F	533_F	0.554	0.50
464_L	486_V	0.554	0.50
205_G	258_F	0.554	0.50
175_I	534_L	0.554	0.50
133_I	546_L	0.552	0.50
442_E	445_L	0.552	0.50
288_S	556_D	0.551	0.50
256_V	588_I	0.551	0.50
248_T	270_Y	0.551	0.50
405_F	413_Q	0.550	0.50
505_N	508_N	0.550	0.50
85_K	186_V	0.550	0.50
268_G	365_I	0.548	0.50
338_K	395_G	0.547	0.49
407_G	416_M	0.546	0.49
360_Q	364_D	0.546	0.49
249_F	294_T	0.545	0.49
83_R	86_E	0.545	0.49
270_Y	581_K	0.543	0.49
156_T	533_F	0.543	0.49
538_F	561_Y	0.543	0.49
110_M	157_V	0.541	0.49
83_R	538_F	0.541	0.49
84_S	247_G	0.541	0.49
113_F	440_L	0.541	0.49
167_I	274_S	0.540	0.49
105_S	168_M	0.539	0.48
21_Y	36_V	0.538	0.48
22_V	41_D	0.538	0.48
269_G	279_L	0.537	0.48
13_K	33_F	0.537	0.48
400_A	405_F	0.537	0.48
109_V	161_C	0.537	0.48
181_L	185_K	0.536	0.48
4_N	7_I	0.536	0.48
166_L	208_G	0.536	0.48
356_T	367_N	0.536	0.48
377_Q	391_K	0.535	0.48
95_M	281_S	0.534	0.48
235_V	503_Q	0.534	0.48
369_M	372_T	0.533	0.48
113_F	161_C	0.533	0.48
426_V	468_L	0.533	0.48
231_N	405_F	0.533	0.48
338_K	341_E	0.532	0.48
306_L	534_L	0.532	0.48
61_S	64_L	0.530	0.47
338_K	347_S	0.530	0.47
404_V	443_E	0.530	0.47
100_I	135_F	0.529	0.47
514_L	518_A	0.529	0.47
457_A	464_L	0.529	0.47
437_Y	447_S	0.529	0.47
381_G	389_S	0.529	0.47
315_Y	615_P	0.528	0.47
3_I	13_K	0.528	0.47
632_F	635_V	0.527	0.47
19_Y	26_I	0.527	0.47
29_V	160_F	0.526	0.47
377_Q	394_K	0.525	0.47
252_Y	293_L	0.525	0.47
188_S	559_P	0.525	0.47
10_N	83_R	0.525	0.47
11_L	106_A	0.524	0.47
399_A	499_E	0.524	0.47
325_V	516_T	0.523	0.46
82_R	556_D	0.523	0.46
73_L	79_F	0.521	0.46
37_T	304_I	0.521	0.46
282_I	584_Y	0.521	0.46
567_L	575_I	0.521	0.46
282_I	570_T	0.520	0.46
259_I	265_K	0.520	0.46
21_Y	548_F	0.519	0.46
76_N	545_I	0.519	0.46
251_F	257_T	0.518	0.46
538_F	566_K	0.518	0.46
337_A	347_S	0.518	0.46
37_T	172_Y	0.518	0.46
75_A	630_F	0.517	0.46
389_S	438_K	0.517	0.46
214_T	385_L	0.517	0.46
268_G	496_K	0.516	0.46
41_D	147_H	0.516	0.46
103_I	192_D	0.516	0.46
118_I	395_G	0.516	0.46
24_A	79_F	0.516	0.46
180_I	201_Q	0.516	0.46
8_L	12_K	0.516	0.46
470_K	502_Q	0.515	0.45
264_R	304_I	0.515	0.45
507_K	510_H	0.515	0.45
76_N	535_G	0.515	0.45
299_V	311_Y	0.514	0.45
353_K	423_V	0.514	0.45
120_V	157_V	0.514	0.45
210_V	218_V	0.514	0.45
41_D	548_F	0.514	0.45
596_H	627_Y	0.513	0.45
98_H	572_G	0.512	0.45
441_R	445_L	0.512	0.45
413_Q	510_H	0.511	0.45
76_N	310_A	0.511	0.45
23_F	37_T	0.510	0.45
90_F	554_S	0.510	0.45
288_S	548_F	0.509	0.45
207_L	397_D	0.509	0.45
84_S	181_L	0.509	0.45
428_S	438_K	0.509	0.45
337_A	341_E	0.509	0.45
71_F	278_S	0.508	0.45
29_V	156_T	0.508	0.45
17_N	278_S	0.507	0.44
296_I	314_Y	0.506	0.44
5_Q	16_R	0.506	0.44
399_A	413_Q	0.506	0.44
390_D	396_V	0.506	0.44
381_G	388_V	0.506	0.44
542_S	600_A	0.506	0.44
4_N	90_F	0.506	0.44
502_Q	505_N	0.506	0.44
276_V	280_S	0.505	0.44
313_S	524_F	0.505	0.44
349_I	354_K	0.505	0.44
501_F	505_N	0.504	0.44
356_T	359_L	0.503	0.44
538_F	549_K	0.502	0.44
284_F	538_F	0.502	0.44
67_V	83_R	0.502	0.44
112_Y	116_L	0.501	0.44
8_L	379_D	0.501	0.44
209_I	510_H	0.501	0.44
179_S	297_T	0.501	0.44
75_A	80_I	0.501	0.44
154_V	617_I	0.500	0.44

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ftjA	1	0.305	97.7	0.923	Contact Map
3is6A	2	0.3235	92	0.95	Contact Map
4b4aA	1	0.3282	15.6	0.974	Contact Map
2l66A	2	0.082	6.5	0.978	Contact Map
1yfbA	2	0.0805	6.4	0.978	Contact Map
1pi7A	1	0.0294	5.8	0.978	Contact Map
3o27A	2	0.0898	5.1	0.979	Contact Map
4khbA	1	0.178	5	0.979	Contact Map
4bbjA	1	0.1053	3.9	0.98	Contact Map
3j09A	2	0.1099	3.7	0.98	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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