STET - BACSU - GREMLIN Contacts

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STET - Serine/threonine exchanger SteT

UniProt:	O34739	Sequences: MHTEDNGLKKEIGLLFALTLVIGTIIGSGVFMKPGAVLAYSGDSKMALFAWLLGGILTLAGGLTIAEIGTQIPKTGGLYTYLEEVYGEFWGFLCGWVQIIIYGPAIIGALGLYFGSLMANLFGWGSGLSKVIGIIAVLFLCVINIIGTKYGGFVQTLTTIGKLIPIACIIVFGLWKGDQHIFTAVNESISDMNFGAAILATLFAYDGWILLAALGGEMKNPEKLLPRAMTGGLLIVTAIYIFINFALLHILSANEIVTLGENATSTAATMLFGSIGGKLISVGIIVSIFGCLNGKVLSFPRVSFAMAERKQLPFAEKLSHVHPSFRTPWIAISFQIALALIMMLISNPDKLSEISIFMIYIFYVMAFFAVFILRKRAKGEKRAYSVPLYPFMPILAIAGSFFVLGSTLITDTMSCGLSILIGLAGLPVYYGMKKRKAS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	438 (415)
Sequences:	24653 (16147)
Seq/√Len:	792.6

ECOLI - FRLA YIFK YBAT AROP PUUP ANSP PLAP GABP PROY LYSP ADIC POTE PHEP MMUP CYCA GADC YCAM CADB YGJI YJEH YJEM ARCD TNAB MTR TYRP
BACSU - STET YTNA YHDG ASPP YFNA ROCC YBEC YVBW GABP YDGF YBXG AAPA YBGF HUTM ROCE YECA ARCD YCGH YDAO GERBB GERAB YNDE GERKB YFKT
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97U05 Q97XM0 Q97X49 Q97WS3 Q97Z63 Q97ZB5 Q7LXI7 Q97VA6 Q97U33 Q97WD4 Q97VA8 Q97VR4 Q97Y76 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
141_C	336_I	4.268	1.00
317_K	330_I	4.245	1.00
372_I	376_R	3.212	1.00
364_V	397_I	3.211	1.00
55_G	237_T	3.090	1.00
320_H	330_I	3.036	1.00
223_K	227_R	2.887	1.00
13_G	219_K	2.828	1.00
322_H	325_F	2.765	1.00
218_M	224_L	2.663	1.00
173_G	246_A	2.578	1.00
79_Y	309_R	2.575	1.00
220_N	223_K	2.551	1.00
95_G	306_M	2.522	1.00
317_K	320_H	2.505	1.00
322_H	329_W	2.501	1.00
307_A	319_S	2.488	1.00
171_V	175_W	2.414	1.00
18_L	231_G	2.396	1.00
134_I	340_L	2.362	1.00
275_I	279_L	2.328	1.00
14_L	231_G	2.318	1.00
216_G	308_E	2.233	1.00
67_E	374_R	2.201	1.00
83_E	91_G	2.153	1.00
217_E	301_R	2.144	1.00
333_S	337_A	2.135	1.00
412_T	415_C	2.135	1.00
416_G	420_L	2.102	1.00
304_F	308_E	2.097	1.00
14_L	224_L	2.089	1.00
17_A	218_M	2.076	1.00
367_F	396_A	2.073	1.00
416_G	419_I	2.070	1.00
266_T	269_T	2.064	1.00
142_V	146_I	2.062	1.00
14_L	18_L	2.037	1.00
138_L	340_L	2.019	1.00
145_I	329_W	2.008	1.00
141_C	332_I	2.002	1.00
134_I	343_M	1.994	1.00
227_R	231_G	1.983	1.00
149_K	153_F	1.983	1.00
255_E	270_M	1.970	1.00
394_I	398_A	1.966	1.00
83_E	88_E	1.922	1.00
425_G	428_V	1.917	1.00
133_G	343_M	1.915	1.00
310_K	316_E	1.914	1.00
160_I	164_I	1.909	1.00
86_Y	372_I	1.884	1.00
182_F	185_V	1.879	1.00
64_T	367_F	1.877	1.00
56_I	60_A	1.874	1.00
99_I	335_Q	1.870	1.00
86_Y	368_F	1.859	1.00
13_G	16_F	1.838	1.00
415_C	418_S	1.838	1.00
8_L	321_V	1.831	1.00
318_L	334_F	1.811	1.00
37_V	47_A	1.811	1.00
252_S	255_E	1.795	1.00
138_L	336_I	1.707	1.00
230_T	234_L	1.695	1.00
220_N	224_L	1.686	1.00
16_F	156_T	1.685	1.00
82_L	94_C	1.680	1.00
178_D	181_I	1.677	1.00
412_T	416_G	1.671	1.00
144_N	293_N	1.662	1.00
368_F	397_I	1.651	1.00
50_A	197_A	1.650	1.00
391_F	395_L	1.649	1.00
398_A	402_F	1.644	1.00
426_L	430_Y	1.631	1.00
94_C	365_M	1.617	1.00
128_L	131_V	1.615	1.00
21_V	232_G	1.598	1.00
427_P	431_G	1.594	1.00
164_I	168_C	1.585	1.00
18_L	235_I	1.579	1.00
425_G	429_Y	1.579	1.00
189_I	192_M	1.576	1.00
266_T	270_M	1.571	1.00
145_I	333_S	1.565	1.00
325_F	329_W	1.548	1.00
127_G	131_V	1.540	1.00
137_V	339_A	1.540	1.00
96_W	425_G	1.539	1.00
415_C	419_I	1.539	1.00
372_I	375_K	1.527	1.00
146_I	325_F	1.511	1.00
12_I	16_F	1.510	1.00
57_L	399_G	1.510	1.00
111_G	292_L	1.502	1.00
56_I	395_L	1.491	1.00
87_G	90_W	1.471	1.00
60_A	395_L	1.461	1.00
234_L	238_A	1.458	1.00
214_L	297_L	1.457	1.00
330_I	334_F	1.441	1.00
269_T	277_G	1.441	1.00
413_M	416_G	1.438	1.00
177_G	249_H	1.435	1.00
165_P	283_G	1.433	1.00
141_C	333_S	1.429	1.00
137_V	336_I	1.417	1.00
322_H	327_T	1.412	1.00
303_S	331_A	1.410	1.00
134_I	138_L	1.408	1.00
299_F	335_Q	1.403	1.00
316_E	319_S	1.400	1.00
174_L	246_A	1.399	1.00
62_G	233_L	1.398	1.00
304_F	321_V	1.398	1.00
188_S	192_M	1.389	1.00
316_E	320_H	1.385	1.00
8_L	304_F	1.367	1.00
86_Y	90_W	1.367	1.00
220_N	227_R	1.359	1.00
278_K	282_V	1.355	1.00
82_L	365_M	1.354	1.00
54_G	201_T	1.349	1.00
414_S	418_S	1.347	1.00
9_K	326_R	1.343	1.00
428_V	431_G	1.342	1.00
72_I	84_E	1.338	1.00
300_P	332_I	1.336	1.00
16_F	152_G	1.333	1.00
177_G	180_H	1.329	1.00
272_F	276_G	1.328	1.00
417_L	420_L	1.326	1.00
170_I	242_F	1.313	1.00
163_L	167_A	1.306	1.00
269_T	274_S	1.304	1.00
184_A	187_E	1.304	1.00
75_T	216_G	1.302	1.00
378_K	382_R	1.298	1.00
221_P	226_P	1.292	1.00
320_H	329_W	1.291	1.00
238_A	242_F	1.284	1.00
368_F	372_I	1.277	1.00
62_G	229_M	1.271	1.00
74_K	80_T	1.271	1.00
313_P	317_K	1.271	1.00
140_L	292_L	1.269	1.00
224_L	227_R	1.264	1.00
107_I	339_A	1.263	1.00
12_I	152_G	1.261	1.00
412_T	418_S	1.261	1.00
14_L	227_R	1.238	1.00
420_L	423_L	1.236	1.00
48_L	245_F	1.232	1.00
99_I	303_S	1.231	1.00
64_T	393_P	1.230	1.00
130_K	134_I	1.229	1.00
303_S	312_L	1.215	1.00
80_T	84_E	1.214	1.00
388_L	392_M	1.213	1.00
118_M	132_I	1.209	1.00
12_I	17_A	1.206	1.00
15_L	19_T	1.201	1.00
61_G	367_F	1.201	1.00
173_G	250_I	1.199	1.00
114_F	285_I	1.190	1.00
371_F	394_I	1.189	1.00
85_V	369_A	1.187	1.00
418_S	422_G	1.185	1.00
419_I	423_L	1.179	1.00
364_V	401_F	1.178	1.00
379_G	382_R	1.172	1.00
25_I	236_V	1.172	1.00
313_P	316_E	1.167	1.00
74_K	84_E	1.166	1.00
63_L	230_T	1.166	1.00
412_T	419_I	1.164	1.00
110_L	113_Y	1.163	1.00
111_G	137_V	1.163	1.00
169_I	173_G	1.157	1.00
426_L	429_Y	1.155	1.00
118_M	122_F	1.155	1.00
65_I	78_L	1.143	1.00
402_F	406_S	1.142	1.00
422_G	425_G	1.127	1.00
391_F	394_I	1.127	1.00
219_K	224_L	1.127	1.00
143_I	154_V	1.120	1.00
185_V	188_S	1.119	1.00
401_F	405_G	1.111	1.00
114_F	136_A	1.102	1.00
71_Q	382_R	1.098	1.00
38_L	47_A	1.094	1.00
131_V	135_I	1.093	1.00
330_I	333_S	1.092	1.00
380_E	383_A	1.083	1.00
154_V	158_T	1.080	1.00
11_E	219_K	1.077	1.00
69_G	81_Y	1.066	1.00
390_P	394_I	1.061	1.00
17_A	228_A	1.059	1.00
108_G	111_G	1.058	1.00
32_M	113_Y	1.057	1.00
408_L	411_D	1.046	1.00
20_L	214_L	1.045	1.00
321_V	326_R	1.043	1.00
141_C	145_I	1.039	1.00
167_A	171_V	1.039	1.00
388_L	391_F	1.037	1.00
135_I	139_F	1.035	1.00
82_L	90_W	1.034	1.00
92_F	96_W	1.030	1.00
168_C	172_F	1.029	1.00
21_V	211_L	1.027	1.00
182_F	186_N	1.025	1.00
308_E	319_S	1.019	1.00
155_Q	293_N	1.018	1.00
67_E	70_T	1.016	1.00
120_N	123_G	1.012	1.00
52_L	241_I	1.012	1.00
22_I	235_I	1.008	1.00
153_F	157_L	1.007	1.00
364_V	400_S	1.002	1.00
375_K	390_P	1.000	1.00
252_S	270_M	0.999	1.00
259_L	266_T	0.998	1.00
79_Y	305_A	0.998	1.00
424_A	428_V	0.993	1.00
111_G	115_G	0.992	1.00
188_S	191_D	0.991	1.00
262_N	266_T	0.990	1.00
22_I	236_V	0.987	1.00
115_G	132_I	0.987	1.00
422_G	426_L	0.986	1.00
337_A	341_I	0.986	1.00
110_L	291_C	0.979	1.00
195_G	402_F	0.977	1.00
320_H	323_P	0.972	1.00
169_I	268_A	0.971	1.00
145_I	327_T	0.964	1.00
158_T	290_G	0.962	1.00
370_V	393_P	0.960	1.00
84_E	377_A	0.959	1.00
423_L	427_P	0.955	1.00
389_Y	393_P	0.952	1.00
148_T	297_L	0.951	1.00
19_T	156_T	0.950	1.00
26_I	29_G	0.949	1.00
170_I	246_A	0.948	1.00
60_A	392_M	0.946	1.00
138_L	142_V	0.945	1.00
425_G	430_Y	0.945	1.00
215_G	225_L	0.942	1.00
397_I	401_F	0.935	1.00
413_M	417_L	0.933	1.00
209_I	213_A	0.931	1.00
89_F	93_L	0.926	1.00
196_A	200_A	0.926	1.00
71_Q	380_E	0.924	1.00
96_W	312_L	0.924	1.00
296_V	336_I	0.923	1.00
415_C	420_L	0.920	1.00
115_G	118_M	0.919	1.00
367_F	397_I	0.913	1.00
364_V	368_F	0.908	1.00
245_F	249_H	0.907	1.00
206_D	359_I	0.907	1.00
139_F	289_F	0.896	1.00
329_W	333_S	0.894	1.00
8_L	217_E	0.891	1.00
414_S	417_L	0.885	1.00
41_S	44_S	0.884	1.00
163_L	239_I	0.873	1.00
231_G	235_I	0.870	1.00
16_F	153_F	0.867	1.00
396_A	400_S	0.863	1.00
83_E	309_R	0.862	1.00
405_G	409_I	0.860	1.00
76_G	80_T	0.860	1.00
419_I	422_G	0.859	1.00
413_M	419_I	0.858	1.00
119_A	123_G	0.858	1.00
250_I	267_A	0.856	1.00
11_E	149_K	0.856	1.00
170_I	174_L	0.856	1.00
76_G	79_Y	0.854	1.00
90_W	365_M	0.850	1.00
393_P	397_I	0.844	1.00
420_L	424_A	0.843	1.00
48_L	248_L	0.843	1.00
49_F	194_F	0.839	1.00
55_G	205_Y	0.839	1.00
237_T	241_I	0.837	1.00
140_L	293_N	0.835	1.00
8_L	301_R	0.835	1.00
312_L	318_L	0.828	1.00
123_G	126_S	0.826	1.00
371_F	393_P	0.825	1.00
59_L	63_L	0.824	1.00
162_K	287_S	0.824	1.00
354_I	358_M	0.821	1.00
132_I	135_I	0.817	1.00
423_L	426_L	0.817	1.00
153_F	156_T	0.816	1.00
184_A	188_S	0.816	1.00
14_L	228_A	0.813	1.00
52_L	56_I	0.811	1.00
15_L	156_T	0.811	1.00
336_I	340_L	0.804	1.00
89_F	426_L	0.801	1.00
382_R	385_S	0.800	1.00
70_T	383_A	0.797	1.00
370_V	374_R	0.795	1.00
210_L	298_S	0.792	1.00
400_S	403_V	0.791	1.00
384_Y	387_P	0.791	1.00
26_I	31_F	0.790	1.00
142_V	145_I	0.785	1.00
145_I	322_H	0.781	1.00
377_A	380_E	0.778	1.00
427_P	430_Y	0.778	1.00
174_L	242_F	0.777	1.00
119_A	122_F	0.775	1.00
274_S	278_K	0.774	1.00
140_L	296_V	0.774	1.00
82_L	369_A	0.771	1.00
26_I	162_K	0.764	1.00
61_G	400_S	0.762	1.00
318_L	330_I	0.761	1.00
59_L	230_T	0.761	1.00
44_S	47_A	0.760	1.00
146_I	150_Y	0.760	1.00
109_A	112_L	0.757	1.00
37_V	41_S	0.755	1.00
425_G	431_G	0.755	1.00
402_F	405_G	0.754	1.00
416_G	422_G	0.752	1.00
68_I	370_V	0.748	1.00
111_G	114_F	0.747	1.00
381_K	385_S	0.747	1.00
11_E	148_T	0.747	1.00
404_L	407_T	0.746	1.00
371_F	390_P	0.745	1.00
144_N	332_I	0.743	1.00
374_R	378_K	0.741	1.00
183_T	186_N	0.737	1.00
115_G	129_S	0.737	1.00
375_K	378_K	0.737	1.00
113_Y	117_L	0.737	1.00
170_I	243_I	0.734	1.00
369_A	373_L	0.732	1.00
118_M	285_I	0.732	1.00
109_A	352_S	0.728	1.00
145_I	325_F	0.727	1.00
115_G	119_A	0.727	1.00
396_A	399_G	0.727	1.00
206_D	363_Y	0.725	1.00
416_G	430_Y	0.723	1.00
273_G	276_G	0.723	1.00
71_Q	383_A	0.722	1.00
30_V	243_I	0.722	1.00
43_D	248_L	0.721	1.00
377_A	382_R	0.720	1.00
195_G	406_S	0.720	1.00
243_I	264_T	0.720	1.00
183_T	187_E	0.717	1.00
134_I	344_L	0.715	1.00
109_A	113_Y	0.714	1.00
412_T	425_G	0.713	1.00
60_A	64_T	0.713	1.00
18_L	21_V	0.712	1.00
18_L	228_A	0.711	1.00
15_L	153_F	0.711	1.00
130_K	343_M	0.710	1.00
68_I	81_Y	0.709	1.00
190_S	193_N	0.709	1.00
109_A	203_F	0.709	1.00
413_M	418_S	0.706	1.00
328_P	331_A	0.704	1.00
423_L	429_Y	0.704	1.00
193_N	196_A	0.703	1.00
418_S	423_L	0.702	1.00
275_I	278_K	0.701	1.00
23_G	159_T	0.700	1.00
371_F	375_K	0.699	1.00
220_N	226_P	0.697	1.00
115_G	133_G	0.696	1.00
380_E	385_S	0.696	1.00
108_G	339_A	0.695	1.00
137_V	343_M	0.694	1.00
268_A	276_G	0.692	1.00
226_P	229_M	0.688	1.00
307_A	318_L	0.688	1.00
405_G	408_L	0.687	1.00
110_L	121_L	0.687	1.00
25_I	232_G	0.686	1.00
300_P	331_A	0.685	1.00
337_A	340_L	0.682	1.00
152_G	156_T	0.678	1.00
71_Q	378_K	0.678	1.00
79_Y	83_E	0.677	1.00
235_I	239_I	0.676	1.00
105_A	355_S	0.674	1.00
144_N	297_L	0.673	1.00
58_T	208_W	0.672	1.00
182_F	249_H	0.672	1.00
98_Q	102_Y	0.662	1.00
11_E	15_L	0.660	1.00
48_L	52_L	0.659	1.00
85_V	372_I	0.658	1.00
414_S	420_L	0.657	1.00
67_E	387_P	0.657	1.00
8_L	11_E	0.656	1.00
358_M	362_F	0.656	1.00
113_Y	116_S	0.654	1.00
416_G	423_L	0.654	1.00
419_I	425_G	0.653	1.00
323_P	329_W	0.653	1.00
130_K	133_G	0.653	1.00
318_L	331_A	0.650	1.00
138_L	141_C	0.649	1.00
79_Y	95_G	0.649	1.00
172_F	176_K	0.649	1.00
296_V	300_P	0.648	1.00
140_L	289_F	0.648	1.00
53_L	198_I	0.648	1.00
111_G	120_N	0.648	1.00
114_F	289_F	0.647	1.00
403_V	407_T	0.646	1.00
136_A	292_L	0.643	1.00
191_D	194_F	0.643	1.00
34_P	244_N	0.643	1.00
47_A	244_N	0.642	1.00
65_I	366_A	0.642	1.00
389_Y	392_M	0.642	1.00
243_I	247_L	0.641	1.00
75_T	304_F	0.640	1.00
212_A	229_M	0.640	1.00
116_S	119_A	0.639	1.00
49_F	53_L	0.637	1.00
49_F	52_L	0.637	1.00
364_V	404_L	0.637	1.00
216_G	304_F	0.636	1.00
301_R	304_F	0.636	1.00
62_G	208_W	0.636	1.00
44_S	194_F	0.634	1.00
103_G	335_Q	0.632	1.00
424_A	427_P	0.630	1.00
268_A	273_G	0.630	1.00
373_L	377_A	0.630	1.00
112_L	116_S	0.629	1.00
317_K	334_F	0.629	1.00
303_S	334_F	0.628	1.00
85_V	373_L	0.624	1.00
69_G	225_L	0.621	1.00
86_Y	369_A	0.621	1.00
51_W	204_A	0.618	1.00
69_G	212_A	0.614	1.00
400_S	404_L	0.613	1.00
15_L	18_L	0.613	1.00
242_F	246_A	0.613	1.00
145_I	332_I	0.612	1.00
177_G	181_I	0.612	1.00
114_F	288_I	0.608	1.00
420_L	425_G	0.608	1.00
172_F	273_G	0.608	1.00
416_G	425_G	0.606	1.00
101_I	359_I	0.606	1.00
225_L	229_M	0.606	1.00
322_H	326_R	0.605	1.00
213_A	298_S	0.604	1.00
150_Y	153_F	0.603	1.00
24_T	294_G	0.602	1.00
21_V	25_I	0.601	1.00
259_L	263_A	0.600	1.00
60_A	396_A	0.598	1.00
62_G	66_A	0.598	1.00
262_N	265_S	0.598	1.00
406_S	410_T	0.597	1.00
66_A	70_T	0.596	1.00
110_L	116_S	0.595	1.00
417_L	422_G	0.595	1.00
107_I	110_L	0.595	1.00
317_K	321_V	0.593	1.00
111_G	116_S	0.592	1.00
107_I	111_G	0.592	1.00
102_Y	295_K	0.592	1.00
79_Y	91_G	0.591	1.00
63_L	392_M	0.591	1.00
137_V	340_L	0.589	1.00
386_V	392_M	0.588	1.00
48_L	241_I	0.588	1.00
110_L	114_F	0.588	1.00
231_G	234_L	0.587	1.00
222_E	383_A	0.587	1.00
255_E	258_T	0.586	1.00
78_L	209_I	0.585	1.00
217_E	328_P	0.583	1.00
97_V	362_F	0.583	1.00
323_P	326_R	0.582	1.00
26_I	239_I	0.582	1.00
246_A	249_H	0.581	1.00
24_T	210_L	0.579	1.00
94_C	362_F	0.577	1.00
161_G	165_P	0.576	1.00
33_K	352_S	0.576	1.00
68_I	85_V	0.576	1.00
148_T	214_L	0.575	1.00
112_L	351_L	0.573	1.00
24_T	295_K	0.573	1.00
282_V	286_V	0.572	1.00
206_D	209_I	0.571	1.00
221_P	224_L	0.571	1.00
420_L	427_P	0.569	1.00
114_F	118_M	0.569	1.00
193_N	197_A	0.568	1.00
161_G	283_G	0.566	1.00
287_S	290_G	0.566	1.00
152_G	293_N	0.565	1.00
423_L	431_G	0.565	1.00
22_I	159_T	0.564	1.00
423_L	430_Y	0.562	1.00
141_C	296_V	0.561	1.00
78_L	213_A	0.561	1.00
263_A	268_A	0.560	1.00
172_F	272_F	0.557	1.00
218_M	225_L	0.557	1.00
418_S	429_Y	0.556	1.00
348_P	352_S	0.554	1.00
150_Y	154_V	0.553	1.00
299_F	303_S	0.553	1.00
418_S	425_G	0.553	1.00
27_G	31_F	0.552	1.00
17_A	214_L	0.552	1.00
414_S	419_I	0.551	1.00
394_I	397_I	0.551	1.00
87_G	91_G	0.548	1.00
349_D	352_S	0.548	1.00
110_L	288_I	0.547	1.00
147_G	150_Y	0.547	1.00
105_A	110_L	0.546	1.00
359_I	362_F	0.546	1.00
156_T	160_I	0.546	1.00
151_G	297_L	0.545	1.00
407_T	411_D	0.545	1.00
54_G	202_L	0.545	1.00
164_I	167_A	0.544	1.00
217_E	321_V	0.542	1.00
251_L	255_E	0.542	1.00
97_V	361_I	0.542	1.00
379_G	383_A	0.541	1.00
360_Y	400_S	0.541	1.00
36_A	349_D	0.541	1.00
235_I	238_A	0.540	1.00
123_G	127_G	0.539	1.00
138_L	333_S	0.539	1.00
103_G	338_L	0.539	1.00
222_E	381_K	0.539	1.00
223_K	226_P	0.538	1.00
159_T	162_K	0.538	1.00
10_K	219_K	0.537	1.00
165_P	279_L	0.537	1.00
235_I	242_F	0.537	1.00
129_S	133_G	0.536	1.00
54_G	205_Y	0.535	1.00
127_G	132_I	0.535	1.00
121_L	282_V	0.535	1.00
321_V	325_F	0.535	1.00
64_T	396_A	0.535	1.00
279_L	283_G	0.534	1.00
31_F	166_I	0.534	1.00
67_E	384_Y	0.534	1.00
104_P	354_I	0.532	1.00
64_T	386_V	0.530	1.00
30_V	166_I	0.530	1.00
301_R	321_V	0.529	1.00
206_D	355_S	0.528	1.00
250_I	271_L	0.528	1.00
117_L	284_I	0.528	1.00
139_F	143_I	0.528	1.00
176_K	271_L	0.528	1.00
423_L	428_V	0.528	1.00
77_G	212_A	0.526	1.00
82_L	91_G	0.526	1.00
105_A	109_A	0.526	1.00
28_S	203_F	0.525	1.00
110_L	292_L	0.525	1.00
357_F	404_L	0.522	1.00
395_L	398_A	0.522	1.00
399_G	403_V	0.522	1.00
374_R	389_Y	0.521	1.00
413_M	420_L	0.521	1.00
209_I	363_Y	0.521	1.00
155_Q	290_G	0.520	1.00
108_G	342_M	0.520	1.00
378_K	381_K	0.520	1.00
382_R	386_V	0.520	1.00
211_L	225_L	0.520	1.00
334_F	338_L	0.517	1.00
221_P	225_L	0.517	1.00
111_G	121_L	0.517	1.00
97_V	101_I	0.516	1.00
136_A	140_L	0.515	1.00
383_A	387_P	0.513	1.00
36_A	39_A	0.512	1.00
47_A	50_A	0.512	1.00
389_Y	394_I	0.511	1.00
13_G	149_K	0.511	1.00
135_I	138_L	0.508	1.00
67_E	385_S	0.508	1.00
278_K	281_S	0.508	1.00
415_C	422_G	0.507	1.00
426_L	431_G	0.507	1.00
108_G	112_L	0.506	1.00
8_L	75_T	0.506	1.00
333_S	336_I	0.506	1.00
329_W	332_I	0.504	1.00
301_R	328_P	0.504	1.00
98_Q	362_F	0.502	1.00
90_W	93_L	0.502	1.00
204_A	240_Y	0.501	1.00
403_V	408_L	0.501	1.00
157_L	160_I	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.9292	100	0.26	Contact Map
3giaA	1	0.9566	100	0.302	Contact Map
4djkA	2	0.9224	100	0.325	Contact Map
2jlnA	1	0.9132	98.6	0.864	Contact Map
3dh4A	3	0.9178	98.6	0.865	Contact Map
2xq2A	2	0.9201	98.5	0.869	Contact Map
2a65A	2	0.9406	97.9	0.889	Contact Map
4wgvA	2	0.8219	97.5	0.898	Contact Map
4xp4A	1	0.9429	96.8	0.908	Contact Map
4us3A	1	0.879	96.5	0.912	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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