OXDC - BACSU - GREMLIN Contacts

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OXDC - Oxalate decarboxylase OxdC

UniProt:	O34714	Sequences: MKKQNDIPQPIRGDKGATVKIPRNIERDRQNPDMLVPPETDHGTVSNMKFSFSDTHNRLEKGGYAREVTVRELPISENLASVNMRLKPGAIRELHWHKEAEWAYMIYGSARVTIVDEKGRSFIDDVGEGDLWYFPSGLPHSIQALEEGAEFLLVFDDGSFSENSTFQLTDWLAHTPKEVIAANFGVTKEEISNLPGKEKYIFENQLPGSLKDDIVEGPNGEVPYPFTYRLLEQEPIESEGGKVYIADSTNFKVSKTIASALVTVEPGAMRELHWHPNTHEWQYYISGKARMTVFASDGHARTFNYQAGDVGYVPFAMGHYVENIGDEPLVFLEIFKDDHYADVSLNQWLAMLPETFVQAHLDLGKDFTDVLSKEKHPVVKKKCSK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	385 (370)
Sequences:	453 (276)
Seq/√Len:	14.3

BACSU - OXDC OXDD

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
116_D	120_R	5.780	1.00
182_A	322_E	4.823	1.00
265_E	328_P	4.591	1.00
100_A	133_Y	4.288	1.00
112_V	227_T	4.081	1.00
111_R	125_D	3.792	1.00
358_Q	365_K	3.617	0.99
286_S	330_V	3.446	0.99
168_L	349_L	3.374	0.99
230_L	246_A	3.362	0.99
177_K	192_S	3.227	0.98
50_F	55_T	3.039	0.98
110_A	142_I	2.911	0.97
105_M	149_A	2.883	0.97
304_N	324_I	2.782	0.96
289_A	329_L	2.778	0.96
106_I	285_I	2.698	0.95
105_M	110_A	2.695	0.95
291_M	313_V	2.647	0.95
27_R	54_D	2.615	0.94
282_Q	311_G	2.604	0.94
288_K	326_D	2.560	0.94
57_N	65_A	2.470	0.92
156_D	256_T	2.441	0.92
114_I	222_V	2.428	0.92
172_L	180_I	2.374	0.91
28_D	53_S	2.371	0.91
88_P	147_E	2.340	0.90
286_S	327_E	2.285	0.89
124_D	229_R	2.278	0.89
290_R	304_N	2.274	0.89
363_L	367_F	2.243	0.88
264_V	329_L	2.224	0.88
58_R	65_A	2.179	0.87
263_T	328_P	2.142	0.86
248_S	258_A	2.099	0.84
356_F	360_H	2.085	0.84
50_F	68_V	2.074	0.84
110_A	149_A	2.066	0.83
55_T	68_V	2.008	0.82
228_Y	233_Q	1.994	0.81
24_N	30_Q	1.975	0.80
114_I	138_L	1.949	0.80
264_V	331_F	1.948	0.79
91_I	356_F	1.932	0.79
48_M	293_V	1.911	0.78
171_W	318_G	1.898	0.78
262_V	331_F	1.898	0.78
24_N	306_Q	1.897	0.78
87_K	90_A	1.870	0.77
73_L	301_R	1.858	0.76
288_K	324_I	1.857	0.76
103_A	131_L	1.856	0.76
105_M	142_I	1.811	0.74
47_N	303_F	1.777	0.73
79_L	154_V	1.771	0.72
262_V	333_E	1.764	0.72
174_H	345_L	1.739	0.71
154_V	334_I	1.732	0.71
133_Y	255_K	1.719	0.70
65_A	292_T	1.692	0.69
282_Q	291_M	1.691	0.69
284_Y	329_L	1.650	0.67
99_E	164_S	1.637	0.66
24_N	27_R	1.635	0.66
174_H	300_A	1.623	0.66
346_N	371_L	1.597	0.64
26_E	30_Q	1.574	0.63
109_S	127_G	1.570	0.63
293_V	317_M	1.526	0.61
27_R	30_Q	1.499	0.59
184_F	191_I	1.498	0.59
23_R	28_D	1.498	0.59
84_M	151_F	1.483	0.58
355_T	359_A	1.470	0.58
171_W	272_L	1.469	0.58
290_R	322_E	1.443	0.56
364_G	367_F	1.442	0.56
133_Y	136_S	1.433	0.56
279_H	315_F	1.419	0.55
231_L	244_Y	1.403	0.54
167_Q	360_H	1.399	0.54
225_P	252_K	1.386	0.53
8_P	12_R	1.374	0.52
91_I	204_N	1.371	0.52
354_E	368_T	1.366	0.52
167_Q	202_F	1.363	0.52
114_I	122_F	1.359	0.52
162_E	198_E	1.352	0.51
172_L	194_L	1.337	0.50
189_E	192_S	1.335	0.50
282_Q	313_V	1.328	0.50
59_L	370_V	1.326	0.50
10_P	16_G	1.319	0.49
166_F	295_A	1.315	0.49
18_T	85_R	1.311	0.49
84_M	162_E	1.311	0.49
21_I	64_Y	1.306	0.49
8_P	29_R	1.304	0.49
327_E	330_V	1.302	0.48
142_I	310_V	1.294	0.48
19_V	28_D	1.294	0.48
127_G	229_R	1.289	0.48
228_Y	232_E	1.282	0.47
180_I	191_I	1.274	0.47
78_N	312_Y	1.269	0.47
248_S	254_S	1.258	0.46
258_A	338_D	1.258	0.46
112_V	142_I	1.235	0.45
204_N	221_E	1.214	0.44
124_D	227_T	1.210	0.43
228_Y	231_L	1.204	0.43
262_V	268_A	1.201	0.43
65_A	90_A	1.200	0.43
142_I	324_I	1.194	0.43
229_R	232_E	1.187	0.42
106_I	340_Y	1.187	0.42
276_P	345_L	1.179	0.42
235_P	242_K	1.173	0.41
60_E	65_A	1.172	0.41
98_K	164_S	1.168	0.41
224_Y	253_V	1.166	0.41
44_T	299_H	1.164	0.41
88_P	144_A	1.155	0.40
82_V	162_E	1.154	0.40
175_T	327_E	1.152	0.40
89_G	276_P	1.151	0.40
122_F	225_P	1.147	0.40
78_N	336_K	1.144	0.40
237_E	265_E	1.143	0.40
202_F	360_H	1.138	0.40
253_V	334_I	1.136	0.39
100_A	257_I	1.134	0.39
149_A	340_Y	1.130	0.39
117_E	341_A	1.130	0.39
175_T	272_L	1.127	0.39
354_E	369_D	1.125	0.39
292_T	299_H	1.116	0.38
132_W	151_F	1.116	0.38
347_Q	375_K	1.113	0.38
52_F	276_P	1.113	0.38
243_V	340_Y	1.108	0.38
9_Q	19_V	1.104	0.38
48_M	303_F	1.100	0.38
180_I	194_L	1.088	0.37
91_I	345_L	1.087	0.37
37_P	56_H	1.084	0.37
217_G	220_G	1.080	0.37
186_V	367_F	1.074	0.36
94_L	294_F	1.073	0.36
70_V	159_S	1.070	0.36
167_Q	198_E	1.068	0.36
284_Y	289_A	1.064	0.36
256_T	272_L	1.062	0.36
107_Y	285_I	1.062	0.36
139_P	148_G	1.060	0.36
177_K	181_A	1.058	0.35
144_A	200_Y	1.052	0.35
174_H	276_P	1.051	0.35
318_G	345_L	1.050	0.35
181_A	213_D	1.049	0.35
166_F	375_K	1.048	0.35
76_S	242_K	1.046	0.35
107_Y	147_E	1.034	0.34
181_A	187_T	1.032	0.34
125_D	145_L	1.030	0.34
18_T	23_R	1.030	0.34
180_I	307_A	1.030	0.34
51_S	69_T	1.029	0.34
105_M	126_V	1.025	0.34
358_Q	368_T	1.024	0.34
156_D	228_Y	1.024	0.34
100_A	255_K	1.018	0.33
215_V	220_G	1.016	0.33
76_S	79_L	1.012	0.33
237_E	242_K	1.007	0.33
266_P	279_H	1.004	0.33
250_N	340_Y	1.004	0.33
228_Y	246_A	1.000	0.33
225_P	228_Y	0.999	0.33
109_S	125_D	0.997	0.32
18_T	283_Y	0.991	0.32
98_K	317_M	0.989	0.32
138_L	305_Y	0.987	0.32
35_L	76_S	0.983	0.32
190_E	367_F	0.978	0.32
113_T	141_S	0.977	0.31
288_K	327_E	0.969	0.31
208_G	212_D	0.967	0.31
90_A	144_A	0.966	0.31
340_Y	343_V	0.964	0.31
73_L	362_D	0.962	0.31
28_D	35_L	0.960	0.31
347_Q	351_M	0.956	0.30
186_V	373_K	0.956	0.30
268_A	331_F	0.956	0.30
166_F	296_S	0.950	0.30
298_G	366_D	0.949	0.30
46_S	283_Y	0.946	0.30
24_N	62_G	0.941	0.30
50_F	282_Q	0.937	0.30
249_T	339_H	0.937	0.30
172_L	272_L	0.927	0.29
50_F	303_F	0.927	0.29
255_K	338_D	0.926	0.29
11_I	18_T	0.924	0.29
234_E	364_G	0.923	0.29
146_E	246_A	0.919	0.29
76_S	340_Y	0.915	0.29
20_K	85_R	0.911	0.28
67_E	99_E	0.911	0.28
256_T	318_G	0.910	0.28
173_A	363_L	0.909	0.28
179_V	269_M	0.906	0.28
133_Y	226_F	0.903	0.28
321_V	331_F	0.901	0.28
327_E	364_G	0.898	0.28
118_K	321_V	0.894	0.28
295_A	317_M	0.884	0.27
51_S	244_Y	0.879	0.27
256_T	336_K	0.878	0.27
65_A	167_Q	0.878	0.27
81_S	242_K	0.876	0.27
161_S	311_G	0.876	0.27
372_S	376_H	0.865	0.26
85_R	139_P	0.862	0.26
18_T	307_A	0.861	0.26
268_A	285_I	0.857	0.26
111_R	145_L	0.855	0.26
8_P	25_I	0.855	0.26
284_Y	305_Y	0.854	0.26
30_Q	258_A	0.854	0.26
213_D	355_T	0.852	0.26
100_A	136_S	0.848	0.26
204_N	359_A	0.846	0.26
81_S	207_P	0.844	0.26
67_E	91_I	0.843	0.26
19_V	26_E	0.841	0.25
171_W	345_L	0.839	0.25
284_Y	291_M	0.839	0.25
164_S	269_M	0.839	0.25
19_V	23_R	0.838	0.25
173_A	289_A	0.838	0.25
333_E	342_D	0.836	0.25
17_A	87_K	0.832	0.25
110_A	126_V	0.832	0.25
278_T	316_A	0.830	0.25
220_G	223_P	0.829	0.25
58_R	200_Y	0.827	0.25
164_S	252_K	0.827	0.25
162_E	167_Q	0.825	0.25
113_T	356_F	0.822	0.25
230_L	233_Q	0.821	0.25
52_F	283_Y	0.815	0.24
367_F	371_L	0.812	0.24
242_K	263_T	0.809	0.24
133_Y	254_S	0.809	0.24
98_K	166_F	0.807	0.24
178_E	322_E	0.805	0.24
262_V	350_A	0.803	0.24
264_V	268_A	0.801	0.24
264_V	321_V	0.801	0.24
289_A	324_I	0.797	0.24
74_P	292_T	0.796	0.24
75_I	264_V	0.790	0.23
117_E	138_L	0.790	0.23
245_I	253_V	0.789	0.23
186_V	192_S	0.788	0.23
313_V	364_G	0.787	0.23
42_H	298_G	0.785	0.23
89_G	345_L	0.782	0.23
56_H	198_E	0.777	0.23
272_L	329_L	0.775	0.23
271_E	344_S	0.775	0.23
48_M	116_D	0.774	0.23
162_E	360_H	0.770	0.23
75_I	291_M	0.770	0.23
350_A	371_L	0.766	0.22
176_P	320_Y	0.764	0.22
167_Q	201_I	0.763	0.22
110_A	310_V	0.762	0.22
104_Y	332_L	0.762	0.22
295_A	298_G	0.760	0.22
215_V	218_P	0.759	0.22
10_P	19_V	0.759	0.22
123_I	142_I	0.751	0.22
170_D	229_R	0.748	0.22
84_M	141_S	0.748	0.22
133_Y	253_V	0.747	0.22
47_N	152_L	0.745	0.22
196_G	307_A	0.744	0.22
30_Q	321_V	0.744	0.22
88_P	337_D	0.743	0.22
128_E	360_H	0.742	0.22
58_R	144_A	0.741	0.21
244_Y	364_G	0.739	0.21
48_M	114_I	0.739	0.21
149_A	169_T	0.737	0.21
160_F	342_D	0.736	0.21
77_E	161_S	0.733	0.21
8_P	23_R	0.731	0.21
55_T	322_E	0.731	0.21
100_A	256_T	0.731	0.21
26_E	29_R	0.731	0.21
46_S	256_T	0.729	0.21
67_E	163_N	0.728	0.21
233_Q	245_I	0.727	0.21
144_A	147_E	0.726	0.21
120_R	222_V	0.724	0.21
120_R	220_G	0.722	0.21
131_L	252_K	0.720	0.21
269_M	331_F	0.718	0.21
278_T	315_F	0.716	0.21
78_N	279_H	0.716	0.21
170_D	318_G	0.715	0.21
123_I	161_S	0.711	0.20
65_A	200_Y	0.709	0.20
24_N	174_H	0.708	0.20
283_Y	340_Y	0.707	0.20
82_V	151_F	0.707	0.20
243_V	331_F	0.706	0.20
338_D	347_Q	0.704	0.20
20_K	123_I	0.703	0.20
227_T	253_V	0.703	0.20
120_R	223_P	0.701	0.20
172_L	349_L	0.701	0.20
73_L	307_A	0.699	0.20
305_Y	363_L	0.698	0.20
67_E	362_D	0.697	0.20
178_E	269_M	0.696	0.20
113_T	123_I	0.696	0.20
111_R	315_F	0.695	0.20
65_A	161_S	0.694	0.20
65_A	162_E	0.691	0.20
20_K	107_Y	0.689	0.20
38_P	260_A	0.688	0.20
145_L	206_L	0.687	0.20
274_W	280_E	0.686	0.20
261_L	330_V	0.686	0.20
112_V	344_S	0.685	0.19
123_I	154_V	0.684	0.19
157_D	336_K	0.682	0.19
222_V	227_T	0.681	0.19
225_P	253_V	0.681	0.19
171_W	174_H	0.681	0.19
126_V	316_A	0.680	0.19
267_G	300_A	0.680	0.19
222_V	226_F	0.678	0.19
49_K	292_T	0.678	0.19
206_L	369_D	0.678	0.19
293_V	311_G	0.675	0.19
75_I	331_F	0.674	0.19
184_F	247_D	0.673	0.19
204_N	235_P	0.673	0.19
157_D	200_Y	0.673	0.19
118_K	187_T	0.672	0.19
154_V	303_F	0.672	0.19
210_L	229_R	0.669	0.19
109_S	154_V	0.668	0.19
128_E	336_K	0.665	0.19
168_L	253_V	0.663	0.19
180_I	187_T	0.663	0.19
50_F	160_F	0.660	0.19
103_A	158_G	0.660	0.19
208_G	213_D	0.660	0.19
28_D	117_E	0.659	0.19
209_S	212_D	0.659	0.19
48_M	54_D	0.655	0.18
148_G	361_L	0.654	0.18
337_D	347_Q	0.653	0.18
137_G	348_W	0.652	0.18
65_A	194_L	0.650	0.18
246_A	373_K	0.649	0.18
115_V	222_V	0.649	0.18
193_N	327_E	0.648	0.18
237_E	372_S	0.647	0.18
349_L	368_T	0.646	0.18
20_K	26_E	0.644	0.18
98_K	157_D	0.642	0.18
170_D	272_L	0.640	0.18
156_D	336_K	0.640	0.18
11_I	17_A	0.639	0.18
324_I	336_K	0.638	0.18
83_N	150_E	0.637	0.18
210_L	214_I	0.634	0.18
194_L	352_L	0.634	0.18
190_E	194_L	0.634	0.18
186_V	191_I	0.633	0.18
228_Y	244_Y	0.633	0.18
123_I	181_A	0.632	0.18
243_V	311_G	0.632	0.18
159_S	164_S	0.631	0.18
13_G	182_A	0.631	0.18
25_I	177_K	0.630	0.18
283_Y	291_M	0.630	0.18
89_G	144_A	0.628	0.18
305_Y	321_V	0.627	0.18
78_N	278_T	0.626	0.18
85_R	163_N	0.624	0.17
121_S	218_P	0.624	0.17
326_D	374_E	0.623	0.17
267_G	310_V	0.621	0.17
288_K	306_Q	0.620	0.17
104_Y	297_D	0.620	0.17
51_S	180_I	0.617	0.17
234_E	237_E	0.617	0.17
21_I	317_M	0.616	0.17
211_K	234_E	0.615	0.17
337_D	375_K	0.615	0.17
180_I	252_K	0.615	0.17
90_A	110_A	0.614	0.17
300_A	345_L	0.610	0.17
150_E	247_D	0.609	0.17
21_I	286_S	0.607	0.17
151_F	267_G	0.607	0.17
142_I	149_A	0.606	0.17
45_V	272_L	0.605	0.17
63_G	66_R	0.605	0.17
154_V	253_V	0.604	0.17
46_S	83_N	0.604	0.17
47_N	50_F	0.603	0.17
198_E	321_V	0.602	0.17
143_Q	349_L	0.602	0.17
200_Y	342_D	0.601	0.17
296_S	339_H	0.601	0.17
147_E	329_L	0.601	0.17
90_A	306_Q	0.601	0.17
258_A	336_K	0.600	0.17
56_H	64_Y	0.597	0.17
118_K	193_N	0.597	0.17
289_A	321_V	0.596	0.17
14_D	321_V	0.595	0.17
106_I	168_L	0.594	0.17
257_I	336_K	0.594	0.17
131_L	246_A	0.594	0.17
211_K	324_I	0.593	0.17
323_N	329_L	0.592	0.16
293_V	313_V	0.592	0.16
249_T	326_D	0.590	0.16
75_I	78_N	0.589	0.16
248_S	252_K	0.589	0.16
294_F	345_L	0.588	0.16
183_N	247_D	0.587	0.16
284_Y	321_V	0.587	0.16
59_L	154_V	0.585	0.16
24_N	253_V	0.584	0.16
151_F	162_E	0.582	0.16
44_T	72_E	0.582	0.16
29_R	52_F	0.581	0.16
91_I	355_T	0.580	0.16
333_E	344_S	0.578	0.16
300_A	326_D	0.577	0.16
74_P	161_S	0.577	0.16
67_E	172_L	0.575	0.16
16_G	303_F	0.573	0.16
173_A	194_L	0.573	0.16
359_A	367_F	0.572	0.16
179_V	320_Y	0.571	0.16
55_T	292_T	0.568	0.16
141_S	292_T	0.568	0.16
93_E	200_Y	0.567	0.16
45_V	68_V	0.567	0.16
226_F	304_N	0.565	0.16
86_L	132_W	0.564	0.16
79_L	115_V	0.563	0.16
224_Y	252_K	0.563	0.16
238_S	340_Y	0.563	0.16
54_D	244_Y	0.561	0.16
286_S	354_E	0.559	0.16
354_E	371_L	0.558	0.15
89_G	174_H	0.557	0.15
124_D	219_N	0.557	0.15
69_T	162_E	0.557	0.15
233_Q	246_A	0.556	0.15
79_L	216_E	0.556	0.15
79_L	257_I	0.554	0.15
338_D	372_S	0.554	0.15
260_A	333_E	0.554	0.15
145_L	238_S	0.554	0.15
52_F	168_L	0.553	0.15
103_A	356_F	0.553	0.15
340_Y	360_H	0.553	0.15
27_R	72_E	0.553	0.15
60_E	162_E	0.552	0.15
233_Q	261_L	0.551	0.15
243_V	246_A	0.551	0.15
199_K	202_F	0.551	0.15
46_S	285_I	0.550	0.15
84_M	161_S	0.550	0.15
84_M	132_W	0.549	0.15
158_G	245_I	0.547	0.15
346_N	372_S	0.547	0.15
139_P	361_L	0.546	0.15
72_E	98_K	0.544	0.15
19_V	306_Q	0.543	0.15
178_E	363_L	0.542	0.15
312_Y	325_G	0.542	0.15
179_V	322_E	0.541	0.15
157_D	252_K	0.541	0.15
189_E	336_K	0.540	0.15
303_F	308_G	0.540	0.15
222_V	225_P	0.540	0.15
148_G	264_V	0.539	0.15
175_T	329_L	0.539	0.15
142_I	263_T	0.539	0.15
79_L	147_E	0.537	0.15
16_G	50_F	0.537	0.15
79_L	248_S	0.536	0.15
336_K	341_A	0.536	0.15
94_L	330_V	0.536	0.15
17_A	85_R	0.533	0.15
22_P	83_N	0.532	0.15
46_S	191_I	0.530	0.15
118_K	149_A	0.530	0.15
112_V	366_D	0.529	0.15
136_S	168_L	0.529	0.15
277_N	294_F	0.528	0.15
228_Y	371_L	0.528	0.15
226_F	239_E	0.527	0.15
146_E	368_T	0.527	0.15
128_E	330_V	0.526	0.15
187_T	191_I	0.526	0.15
80_A	154_V	0.525	0.15
68_V	346_N	0.525	0.15
224_Y	369_D	0.524	0.15
231_L	277_N	0.524	0.15
9_Q	253_V	0.524	0.15
291_M	321_V	0.524	0.15
42_H	73_L	0.521	0.14
114_I	342_D	0.520	0.14
152_L	301_R	0.519	0.14
100_A	105_M	0.519	0.14
46_S	313_V	0.519	0.14
286_S	305_Y	0.519	0.14
72_E	199_K	0.519	0.14
115_V	225_P	0.517	0.14
17_A	306_Q	0.515	0.14
181_A	189_E	0.513	0.14
54_D	178_E	0.513	0.14
65_A	82_V	0.511	0.14
9_Q	28_D	0.511	0.14
157_D	226_F	0.509	0.14
36_V	54_D	0.509	0.14
324_I	356_F	0.508	0.14
124_D	363_L	0.507	0.14
351_M	375_K	0.506	0.14
148_G	202_F	0.506	0.14
257_I	341_A	0.505	0.14
118_K	227_T	0.503	0.14
16_G	47_N	0.503	0.14
272_L	318_G	0.502	0.14
230_L	261_L	0.502	0.14
318_G	368_T	0.501	0.14
42_H	49_K	0.501	0.14
363_L	368_T	0.500	0.14

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1j58A	5	0.9662	100	0.589	Contact Map
2vqaA	3	0.9143	100	0.663	Contact Map
2ea7A	3	0.8857	100	0.694	Contact Map
4lejA	3	0.8286	100	0.694	Contact Map
2e9qA	6	0.839	100	0.695	Contact Map
3qacA	3	0.8442	100	0.698	Contact Map
3kscA	4	0.8416	100	0.699	Contact Map
1uijA	3	0.8649	100	0.703	Contact Map
3kglA	3	0.8675	100	0.703	Contact Map
2cavA	3	0.813	100	0.705	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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