YFLA - BACSU - GREMLIN Contacts

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YFLA - Uncharacterized transporter YflA

UniProt:	O34708	Sequences: MERLLVWIEHISDWLWGPPLIILLTGTGLYFTILLKGFQFRYPLYIFKQTIGSVGKKPKGEGTVTPLQALTSALSSTIGAANIVGVPAAIMFGGPGAVFWMWLIALFAMAIKFSESVLAVHYREKNEQGEYVGGPMYYITKGLRMKWLGVFFSVALIVELIPSIMVQGNSVSVSLAETFSFNKIYAGIGIAFLIGLVVIGGVKRIGKVTEFVVPLMAGAYAGAGLLIVLMNLSSVPAFFSLVFSNAFTSSSAVGGFAGAALAETVRWGFARGLYSNEAGMGTAPIAHAAAMTDHPVRQGFWSVIGIVIDTLIICTTTAFIVLASGVWTGKNASNDPAALTTAAFQHYFGSGGGYFVSVSLVFFVVSTIMVVIFYGVKQAEFLFGRLAGHVIKFVYLAAIIIGAAGGAKAIWGVLDLALVFIVVPNVIALLLLSRKVKALYTEFFTSEQYYLKDIRKTKQKPVYPTKEAKNS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	471 (436)
Sequences:	3787 (2362)
Seq/√Len:	113.1

ECOLI - YAAJ
BACSU - YFLA GLNT YRBD ALST

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
98_V	318_A	4.755	1.00
121_H	439_L	4.103	1.00
224_G	316_T	3.551	1.00
139_I	428_A	3.510	1.00
114_S	436_V	3.310	1.00
232_L	235_V	3.284	1.00
315_T	319_F	3.071	1.00
124_E	141_K	3.036	1.00
143_L	431_L	2.993	1.00
113_F	440_Y	2.930	1.00
240_S	244_S	2.906	1.00
40_F	106_L	2.840	1.00
226_L	230_M	2.804	1.00
239_F	243_F	2.769	1.00
234_S	237_A	2.694	1.00
209_T	366_S	2.642	1.00
34_L	437_K	2.596	1.00
9_E	13_D	2.551	1.00
27_T	430_L	2.541	1.00
208_V	212_V	2.490	1.00
375_G	391_I	2.419	1.00
140_T	146_K	2.417	1.00
241_L	245_N	2.403	1.00
151_F	155_A	2.396	1.00
156_L	378_Q	2.352	1.00
191_A	396_L	2.322	1.00
218_G	222_G	2.270	1.00
10_H	14_W	2.238	1.00
5_L	412_G	2.212	1.00
122_Y	435_K	2.203	1.00
178_T	357_S	2.170	1.00
237_A	240_S	2.108	1.00
27_T	426_V	2.103	1.00
139_I	149_G	2.071	1.00
29_L	107_F	2.064	1.00
204_R	207_K	2.058	1.00
195_G	396_L	2.028	1.00
140_T	381_F	2.025	1.00
238_F	322_L	1.983	1.00
82_N	309_D	1.981	1.00
12_S	416_L	1.976	1.00
248_T	251_S	1.972	1.00
34_L	434_R	1.949	1.00
294_H	442_E	1.935	1.00
8_I	416_L	1.916	1.00
150_V	382_L	1.873	1.00
30_Y	433_S	1.861	1.00
98_V	242_V	1.854	1.00
389_H	392_K	1.843	1.00
229_L	232_L	1.838	1.00
408_K	412_G	1.827	1.00
193_L	361_V	1.816	1.00
45_Y	48_K	1.813	1.00
188_I	192_F	1.796	1.00
8_I	412_G	1.782	1.00
294_H	446_S	1.780	1.00
191_A	400_I	1.772	1.00
423_V	427_I	1.766	1.00
44_L	48_K	1.765	1.00
184_I	400_I	1.735	1.00
334_N	342_A	1.728	1.00
307_V	311_L	1.726	1.00
126_N	130_E	1.700	1.00
212_V	362_F	1.691	1.00
267_W	270_A	1.675	1.00
155_A	420_F	1.671	1.00
376_V	392_K	1.670	1.00
90_I	98_V	1.659	1.00
293_D	297_R	1.652	1.00
296_V	439_L	1.643	1.00
84_V	336_P	1.639	1.00
32_T	39_Q	1.630	1.00
238_F	319_F	1.623	1.00
68_Q	206_G	1.605	1.00
45_Y	443_F	1.593	1.00
240_S	243_F	1.582	1.00
92_F	267_W	1.576	1.00
256_F	259_A	1.573	1.00
345_Q	353_G	1.560	1.00
16_W	419_V	1.544	1.00
36_K	441_T	1.536	1.00
379_A	383_F	1.535	1.00
41_R	444_F	1.531	1.00
140_T	150_V	1.502	1.00
195_G	199_I	1.491	1.00
222_G	226_L	1.485	1.00
146_K	149_G	1.481	1.00
228_V	235_V	1.473	1.00
434_R	438_A	1.465	1.00
24_L	273_L	1.461	1.00
253_V	256_F	1.455	1.00
230_M	233_S	1.450	1.00
439_L	442_E	1.450	1.00
119_A	288_A	1.449	1.00
230_M	347_Y	1.448	1.00
152_F	421_I	1.447	1.00
235_V	238_F	1.447	1.00
71_T	209_T	1.440	1.00
254_G	258_G	1.439	1.00
442_E	446_S	1.437	1.00
6_V	9_E	1.435	1.00
185_Y	189_G	1.426	1.00
182_N	185_Y	1.425	1.00
198_V	372_I	1.419	1.00
109_M	307_V	1.416	1.00
78_I	313_I	1.412	1.00
32_T	37_G	1.412	1.00
228_V	323_A	1.403	1.00
445_T	449_Y	1.402	1.00
287_H	302_S	1.401	1.00
187_G	403_A	1.397	1.00
45_Y	49_Q	1.397	1.00
389_H	393_F	1.394	1.00
228_V	319_F	1.388	1.00
172_S	186_A	1.384	1.00
171_V	190_I	1.379	1.00
7_W	11_I	1.379	1.00
23_L	430_L	1.377	1.00
393_F	397_A	1.376	1.00
34_L	433_S	1.373	1.00
102_W	315_T	1.372	1.00
224_G	320_I	1.367	1.00
121_H	435_K	1.363	1.00
68_Q	210_E	1.361	1.00
35_L	38_F	1.356	1.00
241_L	322_L	1.349	1.00
150_V	154_V	1.345	1.00
11_I	416_L	1.331	1.00
80_A	360_L	1.331	1.00
18_P	22_I	1.329	1.00
66_P	292_T	1.329	1.00
245_N	249_S	1.321	1.00
238_F	323_A	1.314	1.00
139_I	148_L	1.312	1.00
30_Y	34_L	1.303	0.99
437_K	441_T	1.301	0.99
5_L	9_E	1.299	0.99
166_V	414_L	1.288	0.99
228_V	232_L	1.285	0.99
236_P	240_S	1.274	0.99
36_K	444_F	1.273	0.99
413_V	417_A	1.265	0.99
182_N	186_A	1.258	0.99
229_L	233_S	1.252	0.99
207_K	210_E	1.246	0.99
181_F	186_A	1.244	0.99
233_S	236_P	1.236	0.99
280_M	422_V	1.235	0.99
289_A	373_F	1.232	0.99
168_G	403_A	1.229	0.99
8_I	409_A	1.223	0.99
67_L	71_T	1.217	0.99
193_L	365_V	1.205	0.99
329_G	333_S	1.204	0.99
43_P	47_F	1.194	0.99
400_I	404_A	1.191	0.99
184_I	188_I	1.190	0.99
368_I	399_I	1.184	0.99
435_K	438_A	1.181	0.99
152_F	284_P	1.178	0.99
39_Q	110_A	1.171	0.99
106_L	311_L	1.168	0.99
112_K	116_S	1.167	0.99
125_K	131_Y	1.166	0.99
70_L	308_I	1.166	0.99
147_W	151_F	1.166	0.99
65_T	68_Q	1.162	0.99
37_G	40_F	1.161	0.99
324_S	347_Y	1.161	0.99
42_Y	444_F	1.158	0.99
142_G	432_L	1.153	0.99
226_L	348_F	1.146	0.99
321_V	340_T	1.144	0.99
208_V	369_M	1.142	0.99
163_S	371_V	1.138	0.99
286_A	374_Y	1.133	0.99
207_K	211_F	1.131	0.99
30_Y	437_K	1.131	0.99
225_L	229_L	1.129	0.99
11_I	14_W	1.129	0.99
83_I	337_A	1.128	0.99
10_H	13_D	1.127	0.99
324_S	343_A	1.127	0.99
157_I	379_A	1.124	0.99
116_S	302_S	1.120	0.98
383_F	387_A	1.120	0.98
221_A	225_L	1.117	0.98
23_L	423_V	1.116	0.98
31_F	114_S	1.116	0.98
241_L	244_S	1.114	0.98
317_T	340_T	1.111	0.98
244_S	250_S	1.108	0.98
187_G	400_I	1.105	0.98
22_I	26_G	1.099	0.98
342_A	346_H	1.098	0.98
245_N	248_T	1.091	0.98
126_N	132_V	1.089	0.98
235_V	239_F	1.084	0.98
326_V	342_A	1.079	0.98
138_Y	428_A	1.076	0.98
6_V	10_H	1.075	0.98
43_P	307_V	1.072	0.98
231_N	323_A	1.070	0.98
379_A	387_A	1.065	0.98
342_A	345_Q	1.063	0.98
104_I	269_F	1.061	0.98
144_R	147_W	1.060	0.98
42_Y	300_F	1.058	0.98
72_S	202_V	1.056	0.98
117_V	299_G	1.056	0.98
173_V	338_A	1.046	0.98
84_V	170_S	1.042	0.98
221_A	316_T	1.038	0.97
231_N	234_S	1.037	0.97
117_V	296_V	1.032	0.97
185_Y	188_I	1.030	0.97
113_F	296_V	1.028	0.97
255_G	259_A	1.024	0.97
321_V	339_L	1.021	0.97
354_Y	358_V	1.019	0.97
194_I	365_V	1.018	0.97
227_I	347_Y	1.016	0.97
91_M	339_L	1.015	0.97
76_S	370_V	1.013	0.97
232_L	236_P	1.013	0.97
143_L	147_W	1.010	0.97
113_F	117_V	1.009	0.97
422_V	426_V	1.005	0.97
7_W	10_H	1.000	0.97
25_T	104_I	0.993	0.97
401_I	405_G	0.991	0.97
338_A	342_A	0.990	0.97
200_G	204_R	0.989	0.97
304_I	308_I	0.982	0.96
170_S	360_L	0.979	0.96
50_T	301_W	0.978	0.96
212_V	366_S	0.976	0.96
237_A	241_L	0.975	0.96
355_F	359_S	0.975	0.96
68_Q	207_K	0.974	0.96
259_A	262_A	0.970	0.96
66_P	301_W	0.968	0.96
146_K	150_V	0.967	0.96
192_F	196_L	0.967	0.96
42_Y	45_Y	0.964	0.96
87_P	340_T	0.964	0.96
440_Y	444_F	0.961	0.96
109_M	311_L	0.957	0.96
386_L	390_V	0.957	0.96
318_A	322_L	0.956	0.96
277_E	282_T	0.955	0.96
441_T	445_T	0.948	0.96
215_L	219_A	0.945	0.96
176_A	183_K	0.943	0.96
251_S	254_G	0.941	0.96
227_I	344_F	0.939	0.95
348_F	351_G	0.938	0.95
46_I	303_V	0.934	0.95
132_V	377_K	0.933	0.95
135_P	284_P	0.931	0.95
46_I	304_I	0.928	0.95
87_P	321_V	0.928	0.95
275_S	309_D	0.927	0.95
253_V	257_A	0.926	0.95
90_I	322_L	0.925	0.95
20_L	419_V	0.920	0.95
102_W	239_F	0.917	0.95
25_T	273_L	0.917	0.95
234_S	323_A	0.917	0.95
397_A	401_I	0.910	0.95
47_F	304_I	0.903	0.94
228_V	238_F	0.901	0.94
124_E	140_T	0.900	0.94
252_A	255_G	0.899	0.94
156_L	421_I	0.898	0.94
63_T	291_M	0.896	0.94
177_E	338_A	0.896	0.94
163_S	280_M	0.894	0.94
86_V	314_C	0.894	0.94
35_L	437_K	0.893	0.94
45_Y	447_E	0.890	0.94
90_I	318_A	0.890	0.94
4_L	7_W	0.888	0.94
148_L	428_A	0.887	0.94
95_P	241_L	0.885	0.94
158_V	417_A	0.884	0.94
278_A	306_I	0.882	0.94
203_K	207_K	0.880	0.94
293_D	443_F	0.876	0.93
139_I	147_W	0.875	0.93
435_K	439_L	0.875	0.93
173_V	176_A	0.874	0.93
163_S	418_L	0.873	0.93
116_S	305_G	0.872	0.93
323_A	347_Y	0.870	0.93
388_G	392_K	0.870	0.93
131_Y	291_M	0.869	0.93
313_I	316_T	0.867	0.93
250_S	256_F	0.866	0.93
352_G	356_V	0.861	0.93
430_L	433_S	0.860	0.93
194_I	368_I	0.860	0.93
84_V	87_P	0.856	0.93
21_I	25_T	0.856	0.93
23_L	27_T	0.854	0.93
109_M	303_V	0.854	0.93
169_N	411_W	0.853	0.93
394_V	397_A	0.849	0.92
90_I	327_W	0.849	0.92
174_S	341_T	0.847	0.92
77_T	112_K	0.847	0.92
252_A	256_F	0.845	0.92
92_F	257_A	0.844	0.92
88_A	267_W	0.840	0.92
179_F	354_Y	0.840	0.92
165_M	405_G	0.837	0.92
83_I	356_V	0.833	0.92
226_L	229_L	0.833	0.92
256_F	260_A	0.832	0.92
90_I	321_V	0.831	0.92
316_T	320_I	0.829	0.91
386_L	389_H	0.828	0.91
219_A	359_S	0.828	0.91
433_S	437_K	0.828	0.91
114_S	117_V	0.826	0.91
120_V	123_R	0.826	0.91
307_V	312_I	0.825	0.91
74_L	78_I	0.824	0.91
412_G	416_L	0.822	0.91
223_A	359_S	0.819	0.91
9_E	412_G	0.816	0.91
34_L	37_G	0.815	0.91
99_F	247_F	0.815	0.91
335_D	338_A	0.812	0.91
325_G	328_T	0.808	0.90
175_L	361_V	0.805	0.90
4_L	8_I	0.805	0.90
213_V	216_M	0.805	0.90
227_I	320_I	0.804	0.90
233_S	237_A	0.803	0.90
135_P	138_Y	0.802	0.90
431_L	434_R	0.799	0.90
82_N	275_S	0.799	0.90
32_T	40_F	0.799	0.90
99_F	103_L	0.796	0.90
31_F	429_L	0.795	0.90
311_L	315_T	0.794	0.90
284_P	288_A	0.793	0.90
197_V	208_V	0.792	0.89
241_L	327_W	0.790	0.89
205_I	373_F	0.789	0.89
49_Q	301_W	0.785	0.89
124_E	132_V	0.784	0.89
377_K	380_E	0.784	0.89
133_G	288_A	0.783	0.89
28_G	108_A	0.782	0.89
302_S	305_G	0.781	0.89
176_A	186_A	0.780	0.89
64_V	206_G	0.780	0.89
297_R	443_F	0.779	0.89
239_F	319_F	0.779	0.89
194_I	399_I	0.777	0.89
436_V	440_Y	0.775	0.88
78_I	217_A	0.770	0.88
114_S	437_K	0.770	0.88
292_T	297_R	0.769	0.88
245_N	250_S	0.768	0.88
345_Q	349_G	0.768	0.88
164_I	414_L	0.764	0.88
387_A	390_V	0.761	0.88
257_A	260_A	0.758	0.87
38_F	440_Y	0.758	0.87
77_T	302_S	0.755	0.87
15_L	423_V	0.754	0.87
354_Y	357_S	0.753	0.87
70_L	301_W	0.751	0.87
168_G	368_I	0.751	0.87
187_G	404_A	0.750	0.87
170_S	337_A	0.748	0.87
46_I	300_F	0.747	0.87
255_G	262_A	0.745	0.86
202_V	205_I	0.745	0.86
155_A	424_P	0.744	0.86
26_G	430_L	0.744	0.86
173_V	177_E	0.744	0.86
175_L	186_A	0.742	0.86
35_L	440_Y	0.741	0.86
112_K	283_A	0.740	0.86
161_I	394_V	0.739	0.86
5_L	409_A	0.739	0.86
211_F	215_L	0.737	0.86
88_A	91_M	0.735	0.86
239_F	315_T	0.732	0.85
249_S	252_A	0.730	0.85
324_S	327_W	0.727	0.85
371_V	418_L	0.727	0.85
148_L	151_F	0.724	0.85
15_L	19_P	0.724	0.85
301_W	305_G	0.722	0.85
19_P	22_I	0.722	0.85
202_V	373_F	0.721	0.85
14_W	18_P	0.718	0.84
184_I	404_A	0.717	0.84
38_F	42_Y	0.717	0.84
88_A	261_L	0.716	0.84
434_R	441_T	0.714	0.84
257_A	261_L	0.714	0.84
18_P	21_I	0.712	0.84
49_Q	443_F	0.711	0.84
91_M	335_D	0.711	0.84
20_L	422_V	0.711	0.84
230_M	234_S	0.711	0.84
223_A	348_F	0.710	0.84
287_H	305_G	0.709	0.84
166_V	411_W	0.708	0.83
147_W	150_V	0.707	0.83
235_V	319_F	0.706	0.83
213_V	217_A	0.706	0.83
75_S	306_I	0.705	0.83
126_N	377_K	0.704	0.83
242_V	318_A	0.703	0.83
28_G	107_F	0.703	0.83
253_V	259_A	0.702	0.83
345_Q	350_S	0.700	0.83
223_A	355_F	0.700	0.83
50_T	304_I	0.699	0.83
76_S	371_V	0.699	0.83
163_S	414_L	0.697	0.83
199_I	389_H	0.695	0.82
441_T	444_F	0.694	0.82
398_A	401_I	0.689	0.82
21_I	273_L	0.688	0.82
116_S	287_H	0.687	0.82
174_S	337_A	0.686	0.82
108_A	111_I	0.685	0.81
4_L	409_A	0.685	0.81
71_T	210_E	0.683	0.81
127_E	385_R	0.683	0.81
351_G	354_Y	0.679	0.81
80_A	170_S	0.679	0.81
275_S	310_T	0.679	0.81
78_I	308_I	0.679	0.81
165_M	168_G	0.677	0.81
72_S	370_V	0.676	0.81
36_K	44_L	0.676	0.81
217_A	313_I	0.671	0.80
57_K	60_G	0.669	0.80
216_M	275_S	0.663	0.79
150_V	153_S	0.662	0.79
282_T	371_V	0.662	0.79
40_F	44_L	0.661	0.79
434_R	437_K	0.660	0.79
294_H	443_F	0.660	0.79
179_F	186_A	0.658	0.79
405_G	410_I	0.655	0.78
83_I	363_F	0.654	0.78
337_A	360_L	0.653	0.78
7_W	14_W	0.650	0.78
163_S	422_V	0.650	0.78
191_A	195_G	0.649	0.78
244_S	248_T	0.647	0.78
80_A	364_V	0.647	0.78
37_G	106_L	0.645	0.77
341_T	345_Q	0.645	0.77
5_L	408_K	0.644	0.77
249_S	253_V	0.643	0.77
252_A	260_A	0.643	0.77
114_S	440_Y	0.643	0.77
31_F	433_S	0.643	0.77
225_L	228_V	0.642	0.77
243_F	322_L	0.642	0.77
221_A	224_G	0.642	0.77
164_I	395_Y	0.642	0.77
256_F	261_L	0.640	0.77
117_V	436_V	0.640	0.77
4_L	9_E	0.638	0.77
136_M	378_Q	0.637	0.77
98_V	102_W	0.636	0.76
180_S	183_K	0.635	0.76
244_S	249_S	0.633	0.76
231_N	347_Y	0.633	0.76
35_L	114_S	0.633	0.76
252_A	259_A	0.632	0.76
76_S	280_M	0.631	0.76
164_I	371_V	0.630	0.76
320_I	344_F	0.628	0.76
280_M	418_L	0.626	0.75
38_F	110_A	0.624	0.75
70_L	305_G	0.623	0.75
219_A	358_V	0.623	0.75
275_S	311_L	0.621	0.75
350_S	353_G	0.619	0.74
431_L	435_K	0.618	0.74
63_T	131_Y	0.617	0.74
171_V	364_V	0.617	0.74
61_E	125_K	0.616	0.74
319_F	323_A	0.615	0.74
391_I	395_Y	0.614	0.74
234_S	238_F	0.614	0.74
49_Q	297_R	0.614	0.74
187_G	191_A	0.613	0.74
390_V	393_F	0.611	0.74
88_A	407_A	0.610	0.73
103_L	243_F	0.610	0.73
357_S	361_V	0.607	0.73
356_V	359_S	0.605	0.73
8_I	12_S	0.605	0.73
119_A	284_P	0.605	0.73
249_S	259_A	0.605	0.73
113_F	436_V	0.604	0.73
50_T	308_I	0.604	0.73
220_Y	224_G	0.599	0.72
434_R	439_L	0.598	0.72
150_V	381_F	0.597	0.72
193_L	196_L	0.595	0.72
324_S	328_T	0.594	0.71
132_V	380_E	0.593	0.71
77_T	287_H	0.592	0.71
154_V	157_I	0.590	0.71
36_K	434_R	0.588	0.71
171_V	361_V	0.588	0.71
194_I	198_V	0.588	0.71
445_T	448_Q	0.587	0.71
296_V	436_V	0.587	0.71
401_I	404_A	0.585	0.70
160_L	282_T	0.584	0.70
15_L	416_L	0.581	0.70
308_I	312_I	0.581	0.70
236_P	239_F	0.579	0.70
397_A	400_I	0.578	0.69
219_A	223_A	0.576	0.69
102_W	243_F	0.575	0.69
130_E	203_K	0.575	0.69
142_G	145_M	0.575	0.69
64_V	289_A	0.574	0.69
136_M	285_I	0.574	0.69
117_V	439_L	0.573	0.69
287_H	298_Q	0.572	0.69
84_V	360_L	0.572	0.69
138_Y	425_N	0.571	0.68
159_E	418_L	0.569	0.68
186_A	190_I	0.569	0.68
121_H	438_A	0.569	0.68
139_I	145_M	0.568	0.68
232_L	237_A	0.568	0.68
427_I	431_L	0.567	0.68
15_L	422_V	0.566	0.68
101_M	310_T	0.566	0.68
188_I	400_I	0.566	0.68
151_F	154_V	0.565	0.68
165_M	410_I	0.563	0.67
135_P	285_I	0.563	0.67
324_S	329_G	0.563	0.67
367_T	371_V	0.562	0.67
20_L	423_V	0.562	0.67
197_V	365_V	0.557	0.67
31_F	436_V	0.557	0.67
172_S	403_A	0.557	0.67
105_A	310_T	0.557	0.67
76_S	367_T	0.556	0.66
227_I	324_S	0.555	0.66
99_F	243_F	0.555	0.66
62_G	292_T	0.554	0.66
88_A	411_W	0.553	0.66
27_T	31_F	0.553	0.66
368_I	395_Y	0.553	0.66
80_A	171_V	0.552	0.66
66_P	290_A	0.552	0.66
104_I	273_L	0.551	0.66
446_S	449_Y	0.551	0.66
117_V	440_Y	0.549	0.65
153_S	382_L	0.548	0.65
112_K	123_R	0.546	0.65
176_A	180_S	0.546	0.65
326_V	339_L	0.546	0.65
105_A	108_A	0.545	0.65
164_I	391_I	0.545	0.65
84_V	335_D	0.545	0.65
256_F	327_W	0.544	0.65
242_V	322_L	0.544	0.65
249_S	260_A	0.543	0.65
43_P	109_M	0.543	0.65
283_A	374_Y	0.542	0.64
443_F	447_E	0.541	0.64
204_R	292_T	0.541	0.64
42_Y	448_Q	0.541	0.64
114_S	429_L	0.540	0.64
202_V	206_G	0.540	0.64
250_S	253_V	0.540	0.64
20_L	416_L	0.538	0.64
148_L	431_L	0.537	0.64
274_Y	414_L	0.537	0.64
442_E	445_T	0.535	0.63
360_L	367_T	0.535	0.63
373_F	391_I	0.533	0.63
64_V	72_S	0.533	0.63
326_V	346_H	0.533	0.63
111_I	283_A	0.533	0.63
380_E	385_R	0.531	0.63
379_A	390_V	0.531	0.63
173_V	183_K	0.531	0.63
77_T	116_S	0.530	0.63
88_A	336_P	0.530	0.63
327_W	343_A	0.530	0.63
76_S	159_E	0.529	0.63
198_V	392_K	0.529	0.63
288_A	392_K	0.527	0.62
175_L	179_F	0.527	0.62
183_K	186_A	0.526	0.62
245_N	260_A	0.525	0.62
143_L	428_A	0.525	0.62
248_T	252_A	0.525	0.62
340_T	343_A	0.524	0.62
283_A	343_A	0.524	0.62
62_G	291_M	0.522	0.62
234_S	241_L	0.522	0.62
104_I	352_G	0.522	0.62
360_L	364_V	0.522	0.62
48_K	51_I	0.521	0.61
98_V	315_T	0.520	0.61
119_A	283_A	0.519	0.61
46_I	50_T	0.519	0.61
161_I	395_Y	0.518	0.61
114_S	433_S	0.518	0.61
227_I	346_H	0.517	0.61
248_T	256_F	0.517	0.61
83_I	340_T	0.515	0.61
160_L	164_I	0.515	0.61
70_L	74_L	0.514	0.60
86_V	275_S	0.514	0.60
95_P	327_W	0.514	0.60
298_Q	306_I	0.513	0.60
38_F	300_F	0.513	0.60
73_A	77_T	0.513	0.60
111_I	276_N	0.512	0.60
221_A	312_I	0.511	0.60
170_S	336_P	0.511	0.60
82_N	97_A	0.510	0.60
117_V	278_A	0.510	0.60
186_A	189_G	0.509	0.60
23_L	427_I	0.507	0.59
444_F	448_Q	0.507	0.59
159_E	422_V	0.506	0.59
77_T	283_A	0.505	0.59
91_M	338_A	0.504	0.59
420_F	424_P	0.504	0.59
159_E	164_I	0.504	0.59
38_F	113_F	0.504	0.59
126_N	385_R	0.502	0.59
38_F	43_P	0.501	0.58
178_T	353_G	0.501	0.58
46_I	301_W	0.500	0.58
49_Q	300_F	0.500	0.58
41_R	44_L	0.500	0.58

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.7792	99.9	0.858	Contact Map
3giaA	1	0.7813	99.9	0.866	Contact Map
4djkA	2	0.7707	99.6	0.894	Contact Map
2xq2A	2	0.8471	98.2	0.942	Contact Map
4wgvA	2	0.7389	98.2	0.943	Contact Map
3dh4A	3	0.8004	98.1	0.943	Contact Map
4us3A	1	0.7983	97	0.955	Contact Map
2jlnA	1	0.7941	96.7	0.956	Contact Map
2a65A	2	0.8025	96.2	0.958	Contact Map
4xp4A	1	0.8217	95.5	0.961	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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