GREMLIN Database
YTOA - Uncharacterized transferase YtoA
UniProt: O34696 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 171 (146)
Sequences: 8095 (5023)
Seq/√Len: 415.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
54_R76_D3.4541.00
33_Q54_R3.3311.00
53_N75_D2.8971.00
93_N111_G2.8411.00
32_E53_N2.7721.00
63_L71_L2.7321.00
126_I132_A2.7061.00
91_R110_E2.5771.00
31_G53_N2.3711.00
107_E125_I2.2901.00
76_D93_N2.2311.00
115_G133_F2.2031.00
13_H32_E2.1861.00
29_V50_R2.1721.00
74_E92_K2.1711.00
111_G129_G2.1601.00
92_K110_E2.1571.00
110_E128_P2.1241.00
91_R107_E1.9221.00
75_D92_K1.8481.00
121_P124_K1.8241.00
15_T33_Q1.7741.00
89_V107_E1.7511.00
27_D48_P1.7141.00
50_R72_L1.6441.00
72_L89_V1.6151.00
109_G128_P1.5751.00
52_G75_D1.5701.00
39_S60_L1.4731.00
133_F140_I1.4711.00
157_E162_G1.4681.00
34_S75_D1.4401.00
60_L82_Q1.4311.00
109_G125_I1.4281.00
118_S137_A1.4201.00
127_P130_H1.4111.00
144_T147_D1.3891.00
139_V142_P1.3861.00
85_L88_A1.3751.00
127_P139_V1.3361.00
132_A139_V1.3211.00
34_S55_V1.3211.00
57_I61_S1.3151.00
130_H139_V1.3111.00
90_I94_A1.3051.00
112_A130_H1.2731.00
55_V77_A1.2711.00
62_C82_Q1.2611.00
14_P32_E1.2581.00
114_I120_V1.2501.00
19_A38_F1.2151.00
29_V48_P1.1811.00
21_N39_S1.1741.00
31_G50_R1.1711.00
109_G127_P1.1311.00
15_T32_E1.1211.00
82_Q99_G1.1201.00
102_I106_A1.1151.00
40_V61_S1.1121.00
30_I36_I1.1091.00
94_A128_P1.1071.00
42_I49_T1.1021.00
117_G135_R1.0861.00
112_A128_P1.0841.00
74_E91_R1.0731.00
96_I102_I1.0721.00
130_H142_P1.0671.00
55_V92_K1.0581.00
34_S53_N1.0451.00
95_L113_F1.0431.00
94_A112_A1.0401.00
28_V42_I1.0351.00
101_I117_G1.0331.00
73_I77_A1.0151.00
153_R156_S1.0151.00
132_A137_A1.0101.00
129_G148_R0.9931.00
30_I34_S0.9761.00
24_I28_V0.9511.00
55_V75_D0.9501.00
149_K152_Q0.9451.00
54_R159_V0.9341.00
61_S83_V0.9321.00
16_A34_S0.9291.00
12_I16_A0.9281.00
52_G72_L0.9171.00
57_I63_L0.9111.00
154_I158_Y0.9081.00
108_I112_A0.9001.00
103_L106_A0.8961.00
96_I114_I0.8941.00
120_V137_A0.8901.00
36_I40_V0.8781.00
119_L135_R0.8761.00
71_L85_L0.8741.00
18_I22_A0.8741.00
79_I83_V0.8731.00
141_R147_D0.8711.00
57_I79_I0.8651.00
74_E89_V0.8511.00
100_S114_I0.8491.00
73_I79_I0.8411.00
153_R157_E0.8341.00
31_G75_D0.8311.00
79_I85_L0.8201.00
127_P132_A0.8111.00
103_L116_A0.8091.00
112_A126_I0.7921.00
51_I55_V0.7901.00
106_A125_I0.7831.00
36_I42_I0.7791.00
85_L90_I0.7781.00
84_T98_M0.7751.00
101_I119_L0.7651.00
66_S104_D0.7631.00
157_E160_E0.7601.00
55_V73_I0.7571.00
13_H16_A0.7561.00
154_I157_E0.7551.00
91_R128_P0.7491.00
56_N78_T0.7491.00
156_S160_E0.7491.00
118_S135_R0.7481.00
94_A110_E0.7441.00
31_G52_G0.7431.00
131_L143_L0.7381.00
103_L119_L0.7371.00
114_I132_A0.7341.00
23_T39_S0.7331.00
114_I126_I0.7301.00
77_A94_A0.7261.00
99_G117_G0.7261.00
134_G137_A0.7131.00
109_G112_A0.7121.00
90_I96_I0.7111.00
77_A92_K0.7101.00
159_V163_Q0.7061.00
152_Q156_S0.7031.00
159_V162_G0.6901.00
111_G152_Q0.6881.00
96_I100_S0.6861.00
54_R75_D0.6731.00
129_G142_P0.6731.00
33_Q53_N0.6600.99
87_S104_D0.6590.99
101_I116_A0.6580.99
84_T99_G0.6530.99
52_G55_V0.6520.99
46_V65_Q0.6520.99
160_E163_Q0.6390.99
155_R158_Y0.6380.99
111_G148_R0.6370.99
88_A106_A0.6360.99
77_A110_E0.6350.99
106_A120_V0.6290.99
151_M154_I0.6270.99
21_N38_F0.6260.99
150_D153_R0.6250.99
13_H31_G0.6250.99
86_H104_D0.6250.99
47_A65_Q0.6240.99
145_E148_R0.6230.99
102_I108_I0.6200.99
58_Q81_H0.6170.99
91_R109_G0.6090.99
145_E149_K0.6030.99
113_F131_L0.6020.99
16_A53_N0.6010.99
41_V60_L0.6000.99
77_A90_I0.5990.99
17_F20_D0.5960.99
13_H53_N0.5870.99
81_H98_M0.5870.99
119_L133_F0.5870.99
93_N110_E0.5860.99
36_I57_I0.5850.99
51_I57_I0.5850.99
76_D152_Q0.5820.99
149_K153_R0.5790.99
143_L147_D0.5790.99
131_L141_R0.5770.98
91_R94_A0.5750.98
24_I30_I0.5710.98
83_V100_S0.5710.98
37_W43_R0.5710.98
121_P135_R0.5690.98
59_D81_H0.5680.98
78_T154_I0.5660.98
150_D154_I0.5620.98
42_I63_L0.5620.98
147_D150_D0.5620.98
100_S118_S0.5610.98
91_R112_A0.5610.98
71_L86_H0.5610.98
23_T38_F0.5550.98
157_E161_K0.5550.98
155_R159_V0.5530.98
16_A30_I0.5520.98
143_L148_R0.5490.98
85_L102_I0.5480.98
144_T148_R0.5450.98
121_P137_A0.5400.98
12_I30_I0.5350.98
93_N152_Q0.5310.97
47_A66_S0.5290.97
93_N151_M0.5270.97
43_R64_H0.5260.97
59_D62_C0.5250.97
146_E149_K0.5220.97
98_M101_I0.5210.97
64_H86_H0.5210.97
80_G86_H0.5200.97
12_I24_I0.5190.97
156_S159_V0.5170.97
59_D64_H0.5170.97
31_G34_S0.5160.97
46_V157_E0.5150.97
23_T41_V0.5110.97
42_I51_I0.5000.96
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1xhdA 3 0.9883 100 0.261 Contact Map
1v3wA 3 1 100 0.282 Contact Map
3r3rA 3 1 100 0.283 Contact Map
3ixcA 3 0.9474 100 0.285 Contact Map
3r1wA 3 1 100 0.29 Contact Map
4mfgA 3 0.9649 100 0.295 Contact Map
4n27A 3 1 100 0.31 Contact Map
1j2zA 3 0.9766 100 0.339 Contact Map
4r36A 3 0.9883 100 0.342 Contact Map
3r0sA 3 0.9474 100 0.345 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0074 seconds.