GREMLIN Database
YLOA - Uncharacterized protein YloA
UniProt: O34693 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 572 (549)
Sequences: 1701 (1329)
Seq/√Len: 56.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
26_I106_I4.9541.00
88_G106_I4.5541.00
458_T511_E4.4871.00
349_E360_T4.3941.00
121_Y134_T4.3361.00
14_T102_M4.2961.00
90_I104_F4.2371.00
24_G41_I4.1241.00
459_S505_D4.0471.00
487_L499_I3.9691.00
103_I119_K3.9571.00
332_E379_F3.9541.00
90_I106_I3.9531.00
329_L352_N3.8251.00
499_I508_T3.7861.00
61_V102_M3.7811.00
454_T462_T3.7781.00
304_R403_I3.5991.00
476_T538_V3.4461.00
16_E271_S3.4101.00
94_E105_H3.2621.00
457_S508_T3.2601.00
135_D138_E3.2521.00
349_E362_T3.0571.00
347_Q362_T3.0461.00
330_Y364_P2.9731.00
311_I396_I2.9441.00
18_N22_M2.9281.00
41_I90_I2.7811.00
304_R407_D2.6691.00
245_I275_L2.6411.00
18_N92_K2.6071.00
122_V131_I2.6011.00
52_L122_V2.5971.00
183_I226_P2.5921.00
533_T537_H2.5681.00
459_S508_T2.5531.00
489_T492_I2.5381.00
311_I399_A2.4971.00
94_E103_I2.4961.00
269_F278_R2.3911.00
144_G158_V2.3851.00
509_I557_V2.3691.00
10_T102_M2.3051.00
326_E330_Y2.2771.00
492_I522_A2.2521.00
370_T373_E2.2291.00
212_E216_R2.2181.00
174_S177_E2.1671.00
485_I509_I2.1341.00
315_E400_Q2.1321.00
65_A274_E2.1291.00
105_H119_K2.1251.00
331_G379_F2.1241.00
194_L219_L2.1071.00
304_R308_A2.0711.00
461_L505_D2.0641.00
258_E266_A2.0511.00
132_I158_V2.0501.00
178_A202_F2.0441.00
369_K377_A2.0361.00
498_V535_I2.0221.00
331_G378_Y2.0221.00
26_I90_I2.0141.00
20_K48_Q2.0131.00
486_W496_H1.9901.00
505_D508_T1.9661.00
537_H553_S1.9551.00
319_E322_E1.9511.00
518_Y523_K1.9221.00
342_K345_D1.9221.00
15_H239_H1.9111.00
120_L133_L1.9001.00
517_A528_V1.8851.00
64_T277_D1.8701.00
140_V163_D1.8701.00
334_L341_L1.8581.00
457_S463_I1.8430.99
487_L509_I1.8220.99
455_Y465_V1.8180.99
457_S499_I1.8020.99
179_S182_D1.7980.99
157_T162_Q1.7940.99
397_R400_Q1.7680.99
52_L61_V1.7580.99
270_D274_E1.7380.99
5_F13_M1.7370.99
351_I360_T1.7030.99
533_T553_S1.7020.99
255_Y259_L1.6990.99
308_A407_D1.6950.99
341_L348_A1.6920.99
43_A46_K1.6880.99
21_I41_I1.6870.99
317_T392_V1.6810.99
92_K105_H1.6650.99
328_Q332_E1.6600.99
464_L479_V1.6340.99
346_K367_P1.6310.99
22_M92_K1.6210.99
323_N326_E1.6120.99
517_A530_V1.6120.99
26_I88_G1.6100.99
32_P70_N1.5790.98
324_A389_V1.5710.98
235_E240_R1.5670.98
85_I106_I1.5610.98
79_M83_K1.5560.98
330_Y378_Y1.5530.98
485_I504_P1.5360.98
461_L508_T1.5120.98
457_S461_L1.5070.98
247_T267_R1.5040.98
256_L272_L1.4850.98
17_L63_I1.4800.97
195_D211_K1.4650.97
76_M80_L1.4580.97
61_V122_V1.4560.97
497_V516_A1.4520.97
213_A232_L1.4320.97
84_H118_R1.4310.97
15_H19_E1.4300.97
457_S511_E1.4280.97
54_A145_L1.4190.97
392_V396_I1.4180.97
400_Q404_E1.4080.97
271_S274_E1.4070.97
501_S504_P1.4030.97
485_I499_I1.4030.97
216_R235_E1.4030.97
91_E107_K1.3960.96
487_L512_A1.3890.96
24_G43_A1.3830.96
507_Q511_E1.3830.96
475_L479_V1.3650.96
484_D500_R1.3590.96
26_I39_F1.3510.96
337_N340_M1.3480.96
10_T14_T1.3450.96
529_P558_F1.3400.95
494_G516_A1.3380.95
506_E510_M1.3380.95
316_K320_Y1.3330.95
26_I41_I1.3320.95
338_L371_P1.3140.95
332_E335_T1.3120.95
345_D348_A1.3060.95
480_A498_V1.3060.95
103_I166_L1.3050.95
39_F120_L1.2990.95
39_F52_L1.2850.94
531_D551_Y1.2840.94
485_I534_K1.2700.94
541_P550_T1.2690.94
340_M351_I1.2650.94
16_E273_S1.2620.94
104_F122_V1.2610.94
242_I268_R1.2600.94
14_T18_N1.2600.94
459_S507_Q1.2570.94
55_H59_S1.2540.94
12_G256_L1.2530.94
33_Y36_D1.2520.93
333_L353_Y1.2510.93
389_V393_E1.2490.93
332_E353_Y1.2460.93
198_I205_V1.2450.93
317_T388_S1.2440.93
334_L348_A1.2420.93
307_N403_I1.2360.93
475_L480_A1.2350.93
9_F272_L1.2320.93
125_M129_S1.2210.93
7_G95_Q1.2200.93
466_G472_N1.2140.92
228_A231_A1.2140.92
335_T375_A1.2010.92
374_N378_Y1.1990.92
153_N158_V1.1990.92
13_M17_L1.1910.92
497_V515_I1.1870.92
5_F10_T1.1830.91
474_Y479_V1.1820.91
335_T379_F1.1800.91
216_R260_T1.1800.91
462_T500_R1.1780.91
402_E433_Y1.1690.91
234_A238_E1.1620.91
496_H549_V1.1600.91
155_Y165_K1.1540.90
225_L228_A1.1480.90
454_T464_L1.1440.90
96_A103_I1.1400.90
314_L392_V1.1380.90
480_A535_I1.1380.90
487_L508_T1.1380.90
539_K552_D1.1370.90
487_L513_A1.1350.90
499_I504_P1.1320.89
411_Q415_S1.1240.89
48_Q63_I1.1240.89
49_K67_A1.1210.89
492_I521_K1.1210.89
490_K554_Q1.1180.89
199_V210_A1.1160.89
119_K139_N1.1140.89
541_P544_A1.1130.89
481_A500_R1.1110.89
4_S253_Y1.0960.88
11_Y241_F1.0950.88
473_E545_K1.0930.88
134_T139_N1.0910.88
315_E396_I1.0840.87
461_L501_S1.0780.87
313_K317_T1.0730.87
350_V353_Y1.0710.87
37_V131_I1.0640.86
297_E414_S1.0630.86
473_E541_P1.0620.86
318_L389_V1.0590.86
537_H552_D1.0580.86
298_R302_N1.0550.86
74_P82_R1.0440.85
489_T530_V1.0410.85
405_Y469_N1.0380.85
84_H142_I1.0300.84
52_L131_I1.0280.84
464_L475_L1.0250.84
254_F280_Y1.0230.84
463_I512_A1.0230.84
75_P78_C1.0200.84
461_L504_P1.0190.84
541_P545_K1.0160.84
248_V251_K1.0150.84
121_Y166_L1.0140.84
508_T511_E1.0110.83
123_E164_Y1.0100.83
199_V207_P1.0080.83
527_S558_F1.0070.83
97_G174_S1.0010.83
38_I70_N0.9980.83
525_S528_V0.9970.82
183_I229_L0.9960.82
148_L153_N0.9960.82
338_L372_S0.9910.82
308_A403_I0.9880.82
81_L120_L0.9870.82
463_I515_I0.9820.82
17_L61_V0.9790.81
184_L188_S0.9780.81
17_L21_I0.9720.81
88_G108_S0.9710.81
60_R277_D0.9710.81
103_I121_Y0.9700.81
36_D288_R0.9690.81
487_L492_I0.9680.81
21_I48_Q0.9660.80
33_Y68_Y0.9660.80
533_T551_Y0.9640.80
9_F256_L0.9620.80
196_K200_D0.9590.80
50_L63_I0.9560.80
29_I39_F0.9510.79
309_N313_K0.9500.79
103_I139_N0.9430.79
183_I225_L0.9410.79
119_K134_T0.9380.78
413_L421_I0.9360.78
21_I63_I0.9350.78
54_A131_I0.9350.78
325_K328_Q0.9330.78
532_Y557_V0.9290.78
98_L176_L0.9260.78
231_A235_E0.9260.78
452_L479_V0.9250.77
105_H117_V0.9220.77
89_F107_K0.9190.77
43_A48_Q0.9180.77
300_V406_F0.9140.77
334_L337_N0.9110.76
214_V219_L0.9100.76
295_D425_R0.9090.76
483_D535_I0.9090.76
366_N377_A0.9080.76
452_L475_L0.9060.76
435_R441_G0.9030.76
60_R280_Y0.9020.76
356_E360_T0.9020.76
229_L233_F0.9000.76
301_V410_I0.8990.75
74_P79_M0.8940.75
531_D556_T0.8940.75
215_H262_L0.8930.75
472_N488_H0.8920.75
457_S507_Q0.8910.75
233_F237_K0.8880.75
513_A557_V0.8860.74
394_E398_L0.8860.74
258_E268_R0.8860.74
143_D147_H0.8800.74
388_S391_V0.8790.74
168_P376_Q0.8760.74
527_S560_T0.8760.74
457_S505_D0.8710.73
311_I403_I0.8700.73
399_A403_I0.8690.73
378_Y385_A0.8690.73
231_A234_A0.8670.73
329_L337_N0.8670.73
476_T480_A0.8650.73
507_Q510_M0.8600.72
131_I145_L0.8590.72
194_L214_V0.8590.72
214_V217_A0.8560.72
164_Y167_P0.8540.72
267_R278_R0.8530.72
538_V552_D0.8520.71
14_T93_I0.8510.71
405_Y427_E0.8500.71
539_K550_T0.8490.71
178_A183_I0.8490.71
13_M276_L0.8480.71
548_F554_Q0.8470.71
244_N266_A0.8470.71
30_H40_H0.8460.71
202_F205_V0.8460.71
142_I399_A0.8430.71
313_K316_K0.8430.71
230_L234_A0.8400.70
207_P211_K0.8370.70
401_E404_E0.8360.70
97_G203_S0.8330.70
80_L143_D0.8330.70
182_D185_R0.8320.70
476_T535_I0.8300.69
247_T265_E0.8290.69
156_R168_P0.8270.69
510_M514_T0.8270.69
186_H201_H0.8260.69
215_H260_T0.8230.69
461_L502_S0.8210.69
541_P548_F0.8190.68
156_R167_P0.8190.68
459_S499_I0.8180.68
215_H261_H0.8180.68
550_T556_T0.8170.68
36_D68_Y0.8170.68
96_A121_Y0.8170.68
402_E545_K0.8170.68
28_K71_P0.8150.68
411_Q414_S0.8150.68
71_P75_P0.8140.68
317_T320_Y0.8140.68
41_I50_L0.8140.68
90_I93_I0.8130.68
489_T550_T0.8110.68
486_W549_V0.8110.68
139_N163_D0.8110.68
181_D320_Y0.8110.68
125_M156_R0.8090.67
230_L237_K0.8090.67
250_G265_E0.8080.67
335_T383_Q0.8080.67
205_V213_A0.8070.67
193_R197_Q0.8050.67
404_E407_D0.8050.67
499_I505_D0.8030.67
260_T263_K0.8000.67
96_A166_L0.7990.66
427_E469_N0.7990.66
334_L350_V0.7980.66
180_E184_L0.7980.66
51_L60_R0.7970.66
212_E261_H0.7960.66
514_T559_V0.7940.66
455_Y458_T0.7940.66
79_M82_R0.7930.66
544_A550_T0.7930.66
393_E397_R0.7930.66
333_L361_I0.7930.66
63_I93_I0.7920.66
77_F120_L0.7910.66
482_R535_I0.7900.66
406_F409_L0.7890.65
300_V413_L0.7890.65
459_S504_P0.7880.65
310_K395_Q0.7870.65
526_S560_T0.7860.65
475_L498_V0.7840.65
141_I409_L0.7840.65
489_T522_A0.7840.65
542_N545_K0.7840.65
426_E429_V0.7830.65
161_G460_G0.7820.65
20_K46_K0.7820.65
310_K314_L0.7820.65
485_I532_Y0.7800.65
429_V434_L0.7790.65
10_T13_M0.7790.65
395_Q398_L0.7780.64
450_P474_Y0.7770.64
96_A99_D0.7770.64
9_F275_L0.7760.64
71_P79_M0.7700.64
461_L503_E0.7700.64
22_M93_I0.7700.64
30_H70_N0.7690.63
347_Q364_P0.7690.63
178_A182_D0.7680.63
175_P229_L0.7660.63
243_P272_L0.7650.63
545_K556_T0.7640.63
146_K288_R0.7640.63
42_R168_P0.7630.63
27_T42_R0.7620.63
272_L275_L0.7610.63
309_N381_K0.7610.63
332_E528_V0.7600.63
496_H516_A0.7580.62
62_H277_D0.7570.62
333_L350_V0.7550.62
463_I499_I0.7530.62
341_L345_D0.7530.62
179_S234_A0.7520.62
249_N252_E0.7510.62
37_V80_L0.7510.62
347_Q361_I0.7510.62
335_T372_S0.7500.62
464_L500_R0.7500.62
318_L392_V0.7490.61
303_E467_K0.7480.61
4_S206_S0.7460.61
38_I64_T0.7460.61
143_D160_P0.7450.61
219_L223_V0.7440.61
477_T548_F0.7430.61
458_T508_T0.7430.61
387_N391_V0.7420.61
42_R471_Q0.7420.61
29_I85_I0.7400.61
305_K309_N0.7390.60
85_I275_L0.7390.60
181_D185_R0.7370.60
212_E215_H0.7370.60
369_K374_N0.7360.60
216_R232_L0.7340.60
534_K537_H0.7340.60
351_I357_E0.7330.60
204_G384_K0.7310.60
187_L370_T0.7300.59
542_N552_D0.7280.59
351_I355_D0.7260.59
311_I315_E0.7260.59
73_E76_M0.7240.59
88_G107_K0.7240.59
205_V239_H0.7220.59
244_N268_R0.7220.59
542_N548_F0.7210.59
150_P157_T0.7200.58
217_A225_L0.7190.58
493_P496_H0.7180.58
83_K95_Q0.7170.58
99_D470_R0.7170.58
317_T385_A0.7170.58
390_A394_E0.7160.58
123_E156_R0.7130.58
492_I540_K0.7100.57
473_E544_A0.7100.57
221_N224_T0.7090.57
470_R538_V0.7080.57
430_E470_R0.7060.57
91_E117_V0.7060.57
409_L428_L0.7040.57
35_H68_Y0.7040.57
457_S515_I0.7030.57
458_T507_Q0.7020.56
375_A379_F0.7020.56
12_G241_F0.7010.56
227_K231_A0.7010.56
51_L62_H0.7000.56
396_I400_Q0.6990.56
198_I210_A0.6980.56
50_L104_F0.6970.56
127_R149_S0.6960.56
190_Q198_I0.6950.56
488_H494_G0.6930.56
25_R168_P0.6930.56
81_L259_L0.6920.55
173_I186_H0.6910.55
148_L155_Y0.6900.55
8_M236_V0.6890.55
11_Y15_H0.6880.55
347_Q350_V0.6870.55
369_K373_E0.6860.55
394_E397_R0.6860.55
11_Y95_Q0.6840.55
125_M128_H0.6810.54
95_Q99_D0.6790.54
544_A548_F0.6790.54
405_Y409_L0.6780.54
311_I400_Q0.6780.54
460_G484_D0.6780.54
302_N306_K0.6740.53
185_R188_S0.6730.53
312_K315_E0.6720.53
180_E230_L0.6710.53
237_K258_E0.6700.53
121_Y139_N0.6700.53
334_L363_I0.6690.53
473_E552_D0.6680.53
6_D204_G0.6660.53
28_K86_E0.6650.52
465_V519_F0.6640.52
476_T496_H0.6640.52
303_E307_N0.6640.52
24_G48_Q0.6620.52
192_G200_D0.6620.52
144_G147_H0.6620.52
312_K366_N0.6620.52
299_F434_L0.6620.52
469_N546_P0.6610.52
312_K316_K0.6600.52
334_L375_A0.6600.52
209_F255_Y0.6600.52
30_H275_L0.6590.52
104_F447_P0.6550.51
455_Y511_E0.6550.51
9_F99_D0.6540.51
74_P277_D0.6500.51
194_L223_V0.6500.51
187_L194_L0.6500.51
532_Y562_D0.6480.51
410_I562_D0.6470.51
330_Y361_I0.6470.51
66_Q277_D0.6470.51
7_G97_G0.6450.50
226_P230_L0.6450.50
279_F283_K0.6450.50
390_A435_R0.6450.50
379_F383_Q0.6440.50
465_V515_I0.6430.50
556_T559_V0.6420.50
472_N494_G0.6420.50
205_V209_F0.6410.50
492_I541_P0.6390.50
542_N554_Q0.6390.50
78_C336_A0.6370.49
3_M7_G0.6370.49
31_Q71_P0.6360.49
278_R282_G0.6360.49
341_L371_P0.6360.49
117_V136_A0.6340.49
28_K79_M0.6340.49
102_M414_S0.6320.49
403_I407_D0.6310.49
350_V509_I0.6300.49
23_G43_A0.6300.49
246_T258_E0.6290.49
211_K261_H0.6280.48
433_Y545_K0.6280.48
187_L346_K0.6280.48
486_W530_V0.6280.48
205_V210_A0.6270.48
337_N385_A0.6250.48
319_E425_R0.6250.48
496_H546_P0.6250.48
212_E260_T0.6240.48
60_R471_Q0.6220.48
397_R401_E0.6190.47
489_T529_P0.6190.47
280_Y354_Y0.6180.47
205_V236_V0.6170.47
99_D206_S0.6170.47
273_S277_D0.6170.47
375_A378_Y0.6170.47
407_D521_K0.6160.47
180_E264_G0.6160.47
365_L374_N0.6150.47
291_Q295_D0.6150.47
345_D371_P0.6150.47
256_L275_L0.6140.47
489_T541_P0.6140.47
216_R228_A0.6130.47
154_S168_P0.6120.47
366_N374_N0.6110.47
109_R115_E0.6110.47
351_I356_E0.6100.46
477_T535_I0.6090.46
341_L370_T0.6080.46
483_D534_K0.6070.46
12_G135_D0.6060.46
104_F124_I0.6060.46
538_V542_N0.6060.46
181_D503_E0.6050.46
180_E226_P0.6050.46
529_P556_T0.6050.46
314_L399_A0.6040.46
209_F259_L0.6040.46
96_A379_F0.6020.46
329_L353_Y0.6020.46
342_K362_T0.6020.46
55_H383_Q0.6010.46
25_R396_I0.6000.45
407_D411_Q0.5990.45
71_P82_R0.5980.45
456_E462_T0.5970.45
332_E376_Q0.5970.45
428_L433_Y0.5960.45
335_T338_L0.5960.45
350_V363_I0.5950.45
43_A89_F0.5950.45
269_F274_E0.5950.45
299_F473_E0.5940.45
372_S376_Q0.5930.45
15_H315_E0.5920.45
178_A186_H0.5910.44
6_D31_Q0.5910.44
53_S58_Y0.5910.44
321_S421_I0.5900.44
71_P74_P0.5890.44
334_L371_P0.5860.44
532_Y555_H0.5860.44
80_L84_H0.5850.44
246_T262_L0.5850.44
32_P71_P0.5840.44
83_K374_N0.5840.44
315_E319_E0.5830.44
13_M62_H0.5830.44
216_R258_E0.5830.44
209_F257_L0.5820.43
472_N496_H0.5810.43
53_S62_H0.5800.43
54_A124_I0.5800.43
274_E278_R0.5790.43
101_I144_G0.5790.43
101_I272_L0.5780.43
486_W493_P0.5780.43
473_E502_S0.5760.43
465_V516_A0.5760.43
174_S178_A0.5760.43
190_Q197_Q0.5750.43
175_P233_F0.5750.43
241_F256_L0.5750.43
180_E227_K0.5750.43
381_K467_K0.5740.43
335_T376_Q0.5730.42
41_I106_I0.5730.42
457_S512_A0.5720.42
177_E429_V0.5710.42
490_K558_F0.5700.42
20_K63_I0.5700.42
107_K115_E0.5700.42
392_V409_L0.5700.42
468_N471_Q0.5670.42
263_K557_V0.5670.42
15_H18_N0.5670.42
33_Y297_E0.5670.42
314_L395_Q0.5670.42
183_I187_L0.5660.42
190_Q193_R0.5660.42
318_L385_A0.5650.42
347_Q354_Y0.5630.41
363_I374_N0.5620.41
77_F82_R0.5620.41
546_P549_V0.5620.41
213_A228_A0.5610.41
213_A236_V0.5610.41
99_D183_I0.5600.41
39_F446_K0.5590.41
488_H547_G0.5580.41
376_Q525_S0.5580.41
271_S493_P0.5570.41
97_G331_G0.5570.41
37_V81_L0.5570.41
213_A217_A0.5550.41
77_F467_K0.5550.41
492_I529_P0.5550.41
98_L174_S0.5540.40
401_E545_K0.5540.40
8_M257_L0.5540.40
9_F98_L0.5540.40
422_S429_V0.5530.40
371_P375_A0.5530.40
24_G350_V0.5530.40
325_K352_N0.5530.40
118_R142_I0.5520.40
74_P83_K0.5520.40
15_H241_F0.5520.40
212_E262_L0.5510.40
60_R82_R0.5510.40
461_L487_L0.5510.40
65_A239_H0.5500.40
231_A404_E0.5500.40
380_T383_Q0.5500.40
19_E181_D0.5500.40
171_D342_K0.5500.40
147_H160_P0.5500.40
131_I500_R0.5490.40
28_K75_P0.5490.40
451_V479_V0.5490.40
13_M272_L0.5490.40
322_E389_V0.5480.40
77_F84_H0.5470.40
232_L260_T0.5460.40
472_N516_A0.5450.40
268_R281_F0.5450.40
11_Y239_H0.5450.40
504_P509_I0.5440.39
214_V221_N0.5440.39
395_Q467_K0.5440.39
104_F120_L0.5420.39
65_A277_D0.5420.39
126_G129_S0.5420.39
106_I120_L0.5410.39
452_L455_Y0.5410.39
42_R47_N0.5400.39
279_F347_Q0.5390.39
299_F303_E0.5390.39
237_K266_A0.5380.39
486_W561_P0.5380.39
198_I312_K0.5380.39
29_I83_K0.5380.39
60_R64_T0.5370.39
496_H530_V0.5370.39
331_G493_P0.5360.39
334_L492_I0.5360.39
28_K82_R0.5350.38
331_G374_N0.5350.38
423_E526_S0.5350.38
31_Q75_P0.5350.38
186_H202_F0.5350.38
416_A420_D0.5350.38
25_R123_E0.5340.38
90_I562_D0.5340.38
377_A381_K0.5340.38
140_V161_G0.5340.38
277_D284_A0.5330.38
494_G520_S0.5330.38
120_L503_E0.5330.38
307_N402_E0.5330.38
202_F233_F0.5330.38
286_R289_V0.5320.38
12_G243_P0.5310.38
36_D53_S0.5310.38
483_D536_R0.5310.38
163_D270_D0.5300.38
13_M273_S0.5290.38
209_F256_L0.5290.38
187_L197_Q0.5290.38
254_F275_L0.5290.38
304_R399_A0.5280.38
183_I186_H0.5280.38
313_K392_V0.5270.38
51_L64_T0.5270.38
531_D554_Q0.5270.38
376_Q493_P0.5260.38
197_Q201_H0.5260.38
173_I179_S0.5250.37
49_K75_P0.5250.37
356_E361_I0.5250.37
128_H155_Y0.5240.37
554_Q558_F0.5240.37
352_N378_Y0.5240.37
235_E242_I0.5240.37
184_L189_F0.5240.37
209_F452_L0.5240.37
101_I154_S0.5240.37
9_F254_F0.5230.37
551_Y554_Q0.5230.37
408_Q412_Q0.5220.37
77_F133_L0.5210.37
472_N547_G0.5200.37
529_P561_P0.5200.37
512_A538_V0.5200.37
533_T558_F0.5200.37
183_I272_L0.5190.37
13_M126_G0.5180.37
551_Y556_T0.5170.37
23_G91_E0.5170.37
74_P78_C0.5170.37
343_K370_T0.5170.37
497_V512_A0.5170.37
106_I142_I0.5160.37
340_M350_V0.5160.37
108_S116_T0.5150.36
38_I69_E0.5150.36
122_V526_S0.5150.36
402_E434_L0.5150.36
350_V357_E0.5140.36
415_S523_K0.5140.36
246_T259_L0.5140.36
477_T498_V0.5110.36
485_I501_S0.5110.36
181_D316_K0.5100.36
13_M193_R0.5100.36
308_A523_K0.5100.36
290_K293_A0.5100.36
77_F143_D0.5100.36
156_R160_P0.5090.36
307_N399_A0.5090.36
472_N549_V0.5090.36
245_I456_E0.5090.36
242_I258_E0.5090.36
246_T264_G0.5080.36
37_V447_P0.5080.36
119_K136_A0.5070.36
36_D467_K0.5070.36
128_H168_P0.5070.36
244_N275_L0.5070.36
124_I148_L0.5060.36
127_R168_P0.5060.36
156_R384_K0.5050.35
486_W517_A0.5040.35
493_P546_P0.5040.35
533_T542_N0.5040.35
123_E384_K0.5020.35
301_V305_K0.5020.35
332_E551_Y0.5020.35
121_Y454_T0.5020.35
545_K549_V0.5020.35
533_T554_Q0.5010.35
388_S452_L0.5010.35
196_K349_E0.5000.35
333_L409_L0.5000.35
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3doaA 1 0.4598 100 0.599 Contact Map
1ee8A 2 0.3986 99.1 0.92 Contact Map
1k82A 1 0.3724 84.5 0.97 Contact Map
3u6pA 1 0.3514 81.9 0.971 Contact Map
4pd2A 1 0.3934 73.4 0.973 Contact Map
3twlA 1 0.4091 58.7 0.975 Contact Map
1k3xA 1 0.3724 53.1 0.976 Contact Map
3vk8A 1 0.4248 49.5 0.977 Contact Map
4egxA 2 0.2867 40.8 0.978 Contact Map
4mb7A 2 0.4406 36.8 0.978 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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