GREMLIN Database
YJGD - Uncharacterized protein YjgD
UniProt: O34681 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 186 (159)
Sequences: 189 (154)
Seq/√Len: 12.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
59_L66_V6.4771.00
36_A56_L3.2050.97
13_V21_R3.1310.97
26_I38_L3.0790.96
69_I73_K3.0170.96
35_E127_Y3.0050.96
21_R143_I2.9540.95
114_S155_Q2.7970.94
40_T44_L2.5680.91
125_T144_T2.4890.89
29_A38_L2.1710.81
18_Q22_D2.0260.76
62_Q84_K2.0120.76
136_D151_K1.9890.75
26_I37_I1.9730.74
108_V153_M1.9630.74
39_E48_N1.8800.71
142_S153_M1.8630.70
3_K71_V1.7890.67
101_L151_K1.7490.65
149_F153_M1.6930.62
47_M60_F1.6830.62
123_E127_Y1.6630.61
96_L126_G1.6530.60
48_N130_I1.6520.60
85_N96_L1.6120.58
50_R63_G1.5730.56
28_D35_E1.5700.56
4_A154_G1.5610.56
56_L143_I1.4880.52
82_T153_M1.4640.51
43_M74_A1.4440.50
28_D43_M1.4210.49
41_L52_V1.4130.48
64_D67_L1.4060.48
63_G67_L1.4030.48
76_T79_T1.4000.47
31_I156_D1.3720.46
12_E126_G1.3500.45
129_D139_I1.3420.45
37_I152_G1.3190.43
44_L106_L1.2970.42
50_R133_S1.2830.42
2_A154_G1.2770.41
39_E54_P1.2610.41
10_K28_D1.2560.40
60_F112_V1.2430.40
22_D44_L1.2270.39
142_S145_L1.2210.39
81_N100_Q1.2180.38
19_R28_D1.2130.38
15_E19_R1.1980.38
17_D108_V1.1600.36
60_F74_A1.1570.36
83_L123_E1.1570.36
83_L99_K1.1510.35
89_L94_G1.1440.35
137_P154_G1.1340.35
141_K150_L1.1190.34
44_L83_L1.1140.34
73_K76_T1.1070.33
50_R55_L1.0840.32
97_D104_L1.0810.32
84_K101_L1.0690.32
4_A84_K1.0650.31
4_A32_D1.0630.31
65_K117_E1.0430.30
125_T140_N1.0350.30
108_V131_I1.0230.30
90_F94_G1.0200.30
80_A151_K1.0190.29
25_E34_K1.0110.29
32_D39_E1.0010.29
64_D78_E1.0000.29
101_L143_I0.9990.29
47_M53_L0.9990.29
52_V110_A0.9960.29
25_E108_V0.9880.28
27_E92_T0.9800.28
38_L83_L0.9760.28
25_E146_L0.9710.27
14_T143_I0.9700.27
64_D134_L0.9640.27
26_I36_A0.9590.27
8_I99_K0.9580.27
64_D135_K0.9470.27
20_K23_L0.9440.26
51_G132_R0.9280.26
46_H70_L0.9280.26
29_A105_I0.9270.26
37_I112_V0.9240.26
124_K140_N0.9190.25
85_N94_G0.9190.25
10_K49_E0.9150.25
82_T91_G0.9110.25
83_L97_D0.9060.25
12_E58_G0.9020.25
66_V112_V0.8980.25
56_L144_T0.8980.25
61_G112_V0.8960.25
139_I154_G0.8880.24
6_K141_K0.8880.24
3_K59_L0.8850.24
24_R104_L0.8820.24
96_L110_A0.8760.24
1_M5_I0.8740.24
43_M82_T0.8710.24
63_G150_L0.8680.24
41_L127_Y0.8580.23
27_E67_L0.8560.23
44_L49_E0.8550.23
8_I149_F0.8510.23
24_R147_F0.8480.23
27_E33_H0.8460.23
66_V69_I0.8380.22
65_K122_E0.8350.22
25_E29_A0.8340.22
142_S150_L0.8250.22
70_L135_K0.8230.22
22_D29_A0.8200.22
14_T141_K0.8190.22
36_A53_L0.8170.22
17_D83_L0.8110.22
97_D111_G0.8020.21
78_E94_G0.8020.21
7_R85_N0.8010.21
59_L148_S0.7980.21
26_I34_K0.7970.21
115_A148_S0.7960.21
43_M60_F0.7910.21
42_H86_L0.7860.21
5_I155_Q0.7820.21
36_A58_G0.7790.20
60_F116_V0.7790.20
59_L132_R0.7670.20
21_R54_P0.7660.20
35_E123_E0.7640.20
14_T17_D0.7620.20
71_V117_E0.7610.20
75_D85_N0.7540.20
68_D143_I0.7440.19
63_G84_K0.7340.19
126_G129_D0.7340.19
44_L118_Q0.7340.19
35_E90_F0.7340.19
38_L127_Y0.7330.19
44_L129_D0.7290.19
81_N149_F0.7200.19
3_K18_Q0.7190.19
107_K157_T0.7100.18
138_E151_K0.7070.18
5_I17_D0.7010.18
16_E26_I0.7010.18
2_A5_I0.6960.18
143_I147_F0.6960.18
17_D90_F0.6950.18
34_K135_K0.6930.18
62_Q155_Q0.6880.18
52_V111_G0.6830.17
16_E124_K0.6760.17
138_E157_T0.6750.17
17_D37_I0.6740.17
3_K113_A0.6740.17
26_I131_I0.6730.17
13_V17_D0.6730.17
40_T129_D0.6700.17
70_L73_K0.6690.17
72_K89_L0.6680.17
115_A157_T0.6680.17
34_K105_I0.6650.17
76_T87_L0.6610.17
75_D94_G0.6480.16
1_M154_G0.6470.16
33_H96_L0.6430.16
73_K92_T0.6350.16
133_S140_N0.6340.16
5_I45_G0.6320.16
98_V157_T0.6310.16
52_V101_L0.6300.16
7_R52_V0.6280.16
29_A94_G0.6220.16
109_N144_T0.6190.16
58_G137_P0.6150.16
33_H135_K0.6140.16
70_L92_T0.6130.16
32_D52_V0.6110.15
130_I133_S0.6040.15
41_L139_I0.6020.15
30_L149_F0.6010.15
56_L135_K0.5950.15
34_K38_L0.5950.15
63_G140_N0.5930.15
19_R70_L0.5930.15
71_V115_A0.5910.15
133_S137_P0.5840.15
80_A101_L0.5840.15
33_H41_L0.5830.15
12_E70_L0.5790.15
70_L76_T0.5760.15
111_G152_G0.5730.14
5_I82_T0.5720.14
15_E134_L0.5680.14
85_N148_S0.5600.14
13_V89_L0.5600.14
62_Q141_K0.5560.14
71_V103_P0.5540.14
56_L148_S0.5540.14
5_I150_L0.5530.14
13_V26_I0.5520.14
145_L157_T0.5440.14
16_E23_L0.5440.14
6_K25_E0.5420.14
137_P150_L0.5420.14
104_L130_I0.5400.14
26_I138_E0.5370.14
76_T80_A0.5340.14
95_M116_V0.5340.14
13_V143_I0.5330.13
149_F154_G0.5320.13
3_K102_E0.5320.13
81_N91_G0.5300.13
5_I8_I0.5300.13
55_L63_G0.5290.13
40_T58_G0.5280.13
54_P61_G0.5280.13
84_K146_L0.5280.13
31_I73_K0.5270.13
42_H130_I0.5220.13
53_L150_L0.5210.13
19_R27_E0.5200.13
1_M8_I0.5190.13
32_D101_L0.5140.13
69_I91_G0.5140.13
19_R23_L0.5090.13
32_D151_K0.5090.13
84_K103_P0.5050.13
48_N82_T0.5010.13
26_I149_F0.5000.13
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1k8kG 1 0.6613 17.2 0.948 Contact Map
2d6fC 1 0.0538 9.6 0.953 Contact Map
1hx1B 1 0.3871 8.9 0.954 Contact Map
1sj7A 2 0.5269 8.9 0.954 Contact Map
1i6zA 1 0.457 7.7 0.955 Contact Map
1r1tA 2 0.4839 6.4 0.957 Contact Map
1pu6A 1 0.7473 6.4 0.957 Contact Map
3p3vA 1 0.5968 6.1 0.957 Contact Map
3bpqA 2 0.2097 5.7 0.958 Contact Map
2jnkA 1 0.6022 5.6 0.958 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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