GREMLIN Database
YTGP - Probable cell division protein YtgP
UniProt: O34674 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 544 (464)
Sequences: 14657 (12449)
Seq/√Len: 577.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
324_N327_L5.1721.00
105_S108_M3.2791.00
76_D79_T3.2491.00
464_K468_L3.2161.00
243_F247_S3.1301.00
156_M159_P3.0511.00
43_Q291_T2.9901.00
401_K404_F2.9671.00
351_S377_L2.6921.00
373_A377_L2.6581.00
401_K454_H2.6501.00
403_K407_V2.5731.00
155_Q318_E2.5481.00
465_R468_L2.4001.00
103_Y132_R2.3861.00
419_L435_A2.2871.00
289_I371_L2.2711.00
355_G359_T2.2511.00
479_A514_V2.1911.00
385_L441_I2.1861.00
354_S373_A2.1801.00
412_G443_S2.1761.00
128_V132_R2.1551.00
319_S327_L2.1311.00
266_D290_L2.1281.00
476_M480_V2.1161.00
68_V153_G2.0871.00
318_E322_S2.0741.00
266_D420_N2.0681.00
378_W430_D2.0481.00
82_K238_Y2.0331.00
375_I429_A2.0081.00
348_V477_G2.0001.00
349_G353_L1.9881.00
254_F406_V1.9871.00
102_L135_S1.9831.00
330_Q334_Q1.9751.00
378_W437_A1.9561.00
408_S446_Y1.9511.00
193_A196_Y1.9381.00
325_Y329_N1.9201.00
239_K243_F1.9191.00
266_D436_T1.9111.00
354_S377_L1.9001.00
107_P128_V1.8961.00
349_G508_A1.8951.00
427_M434_L1.8931.00
269_T424_I1.8781.00
341_F519_G1.8641.00
320_F399_I1.8411.00
424_I432_A1.7831.00
67_F248_Y1.7681.00
11_V158_G1.7651.00
343_I387_S1.7591.00
332_I395_I1.7521.00
512_G516_L1.7511.00
106_A132_R1.7401.00
79_T82_K1.7171.00
238_Y241_M1.7131.00
445_L449_I1.6831.00
378_W434_L1.6791.00
415_I442_A1.6741.00
475_I518_C1.6701.00
327_L330_Q1.6581.00
270_F274_M1.6541.00
70_K400_N1.6521.00
269_T420_N1.6421.00
344_I473_S1.6411.00
274_M286_M1.6401.00
35_G38_G1.6381.00
347_V384_I1.6321.00
84_L150_F1.6311.00
356_P359_T1.6251.00
81_R85_K1.6211.00
355_G373_A1.6131.00
482_I485_W1.6131.00
353_L356_P1.6051.00
363_G366_S1.5901.00
45_G134_V1.5721.00
66_K70_K1.5611.00
316_I328_L1.5591.00
477_G481_K1.5571.00
431_G435_A1.5551.00
156_M219_R1.5491.00
476_M511_G1.5321.00
171_R175_L1.5291.00
31_S293_Y1.5271.00
176_L180_F1.5231.00
472_L518_C1.5201.00
326_K330_Q1.5111.00
328_L395_I1.5091.00
258_A410_V1.5041.00
423_L427_M1.4971.00
269_T421_V1.4931.00
374_N377_L1.4901.00
480_V511_G1.4901.00
32_I363_G1.4881.00
168_Q171_R1.4871.00
374_N430_D1.4811.00
421_V425_K1.4641.00
358_Y372_G1.4611.00
435_A439_G1.4611.00
378_W433_I1.4551.00
408_S450_M1.4471.00
213_Y217_N1.4451.00
420_N424_I1.4411.00
422_P426_L1.4361.00
362_Y365_E1.4331.00
353_L357_T1.4221.00
274_M429_A1.4121.00
155_Q315_T1.4081.00
423_L435_A1.4051.00
407_V411_I1.3991.00
44_Y271_N1.3911.00
355_G377_L1.3851.00
108_M112_I1.3851.00
472_L476_M1.3831.00
270_F432_A1.3791.00
422_P425_K1.3731.00
275_I286_M1.3651.00
171_R174_F1.3621.00
349_G476_M1.3611.00
327_L331_Q1.3611.00
511_G515_Y1.3551.00
270_F287_L1.3511.00
320_F328_L1.3421.00
449_I453_R1.3391.00
72_N80_S1.3391.00
150_F154_H1.3371.00
42_F46_Y1.3321.00
265_I417_L1.3311.00
87_G245_L1.3311.00
350_I380_S1.3301.00
124_I128_V1.3241.00
158_G162_V1.3221.00
177_S181_L1.3191.00
473_S477_G1.3151.00
515_Y519_G1.3151.00
385_L444_L1.3081.00
286_M429_A1.3081.00
428_Q431_G1.3031.00
469_M472_L1.3011.00
319_S331_Q1.2991.00
17_Y21_I1.2981.00
518_C522_L1.2861.00
294_V375_I1.2781.00
170_V207_G1.2761.00
418_V422_P1.2681.00
332_I392_N1.2641.00
312_L335_T1.2631.00
423_L426_L1.2621.00
106_A128_V1.2601.00
465_R469_M1.2561.00
416_K420_N1.2511.00
36_A289_I1.2501.00
329_N333_N1.2491.00
86_A242_F1.2481.00
289_I372_G1.2431.00
375_I433_I1.2371.00
107_P132_R1.2371.00
482_I486_V1.2371.00
325_Y399_I1.2301.00
107_P111_E1.2271.00
340_L344_I1.2261.00
350_I376_L1.2211.00
27_L296_K1.2201.00
196_Y200_A1.2191.00
43_Q288_A1.2171.00
251_P406_V1.2101.00
485_W488_G1.2091.00
410_V414_V1.2041.00
430_D433_I1.2031.00
130_V198_T1.2001.00
99_F103_Y1.1991.00
129_Y195_G1.1911.00
90_V242_F1.1881.00
93_V97_I1.1871.00
82_K86_A1.1861.00
382_V437_A1.1851.00
371_L374_N1.1821.00
64_V87_G1.1791.00
18_I165_V1.1741.00
178_A183_L1.1731.00
67_F244_E1.1701.00
358_Y376_L1.1691.00
415_I419_L1.1681.00
140_V206_F1.1661.00
313_I317_T1.1631.00
516_L520_Y1.1531.00
106_A110_A1.1511.00
420_N436_T1.1491.00
408_S447_G1.1441.00
356_P484_Q1.1431.00
319_S324_N1.1421.00
416_K436_T1.1411.00
199_F203_I1.1391.00
167_E171_R1.1391.00
250_A254_F1.1381.00
174_F177_S1.1361.00
270_F290_L1.1361.00
70_K244_E1.1271.00
244_E400_N1.1171.00
174_F200_A1.1171.00
24_M28_I1.1161.00
407_V410_V1.1151.00
392_N448_F1.1141.00
333_N337_Q1.1131.00
139_L142_P1.1121.00
348_V473_S1.1101.00
171_R204_G1.1061.00
505_V509_A1.1051.00
414_V418_V1.0981.00
375_I430_D1.0961.00
63_A248_Y1.0951.00
266_D416_K1.0921.00
360_F504_V1.0911.00
358_Y373_A1.0901.00
381_P437_A1.0801.00
434_L438_L1.0801.00
174_F178_A1.0711.00
136_L139_L1.0691.00
347_V351_S1.0681.00
507_A511_G1.0671.00
63_A249_A1.0661.00
28_I32_I1.0591.00
136_L202_L1.0571.00
63_A245_L1.0551.00
316_I398_G1.0541.00
85_K89_S1.0481.00
163_S211_V1.0421.00
508_A511_G1.0351.00
298_V379_Y1.0311.00
69_S153_G1.0301.00
294_V379_Y1.0291.00
21_I25_V1.0281.00
261_L413_V1.0271.00
71_Y79_T1.0251.00
15_G161_A1.0251.00
396_L450_M1.0241.00
89_S93_V1.0231.00
388_L444_L1.0231.00
264_Y267_T1.0221.00
258_A406_V1.0181.00
508_A512_G1.0151.00
351_S354_S1.0141.00
170_V174_F1.0131.00
210_V214_I1.0131.00
397_Q405_A1.0131.00
419_L423_L1.0091.00
40_A288_A1.0071.00
36_A288_A1.0051.00
446_Y449_I1.0001.00
395_I451_I1.0001.00
108_M111_E0.9981.00
101_I105_S0.9961.00
470_L473_S0.9961.00
126_H129_Y0.9941.00
110_A127_V0.9901.00
65_S149_G0.9901.00
484_Q507_A0.9831.00
446_Y450_M0.9801.00
469_M473_S0.9791.00
262_Y416_K0.9771.00
449_I452_K0.9771.00
27_L362_Y0.9711.00
427_M431_G0.9711.00
500_A503_V0.9701.00
472_L522_L0.9691.00
420_N423_L0.9681.00
294_V372_G0.9661.00
452_K455_A0.9661.00
258_A413_V0.9661.00
199_F202_L0.9651.00
467_V471_V0.9631.00
19_S168_Q0.9591.00
45_G130_V0.9561.00
360_F501_A0.9551.00
251_P403_K0.9551.00
68_V80_S0.9541.00
4_K7_R0.9521.00
255_V405_A0.9521.00
478_I482_I0.9501.00
353_L507_A0.9461.00
31_S362_Y0.9451.00
106_A135_S0.9441.00
79_T241_M0.9431.00
246_F249_A0.9431.00
140_V209_L0.9431.00
68_V154_H0.9401.00
468_L472_L0.9381.00
416_K439_G0.9381.00
88_M147_V0.9361.00
326_K329_N0.9331.00
57_T61_P0.9331.00
132_R136_L0.9331.00
9_T311_T0.9311.00
357_T361_F0.9311.00
370_E374_N0.9291.00
40_A276_E0.9281.00
481_K484_Q0.9271.00
348_V352_L0.9261.00
66_K400_N0.9251.00
315_T318_E0.9251.00
382_V433_I0.9241.00
392_N447_G0.9241.00
269_T273_A0.9231.00
377_L381_P0.9221.00
93_V96_M0.9221.00
129_Y132_R0.9211.00
184_K193_A0.9211.00
179_T182_I0.9171.00
404_F450_M0.9161.00
331_Q335_T0.9151.00
135_S139_L0.9121.00
26_Y172_I0.9121.00
39_G43_Q0.9051.00
288_A293_Y0.9031.00
173_I177_S0.9031.00
103_Y107_P0.9021.00
195_G198_T0.8991.00
419_L438_L0.8981.00
372_G375_I0.8981.00
12_L311_T0.8981.00
97_I101_I0.8971.00
104_L108_M0.8961.00
345_P515_Y0.8941.00
460_K464_K0.8901.00
258_A409_L0.8891.00
481_K485_W0.8891.00
83_M87_G0.8881.00
9_T308_F0.8861.00
365_E370_E0.8851.00
411_I446_Y0.8841.00
241_M244_E0.8821.00
99_F139_L0.8811.00
396_L405_A0.8811.00
99_F102_L0.8801.00
248_Y402_Q0.8771.00
80_S154_H0.8761.00
252_Y402_Q0.8751.00
215_Y219_R0.8711.00
78_E82_K0.8671.00
30_F197_A0.8651.00
177_S180_F0.8601.00
110_A128_V0.8581.00
349_G511_G0.8581.00
47_N267_T0.8551.00
319_S322_S0.8551.00
200_A204_G0.8541.00
271_N287_L0.8541.00
148_R152_Q0.8531.00
170_V173_I0.8511.00
172_I176_L0.8491.00
42_F197_A0.8471.00
147_V213_Y0.8451.00
28_I362_Y0.8411.00
10_F14_L0.8401.00
345_P348_V0.8401.00
174_F203_I0.8391.00
370_E373_A0.8371.00
137_A205_A0.8361.00
157_M311_T0.8361.00
77_Y81_R0.8351.00
125_D129_Y0.8341.00
96_M100_F0.8331.00
437_A440_Y0.8321.00
351_S380_S0.8281.00
334_Q337_Q0.8261.00
95_G142_P0.8251.00
104_L107_P0.8231.00
92_L96_M0.8211.00
298_V383_A0.8201.00
5_L9_T0.8201.00
159_P215_Y0.8181.00
483_V510_V0.8141.00
328_L399_I0.8111.00
71_Y76_D0.8111.00
67_F70_K0.8111.00
163_S212_L0.8101.00
63_A67_F0.8041.00
36_A365_E0.8031.00
29_P33_M0.8021.00
217_N220_K0.8021.00
44_Y287_L0.7991.00
214_I218_K0.7971.00
140_V202_L0.7971.00
473_S476_M0.7971.00
247_S403_K0.7961.00
33_M179_T0.7951.00
41_L276_E0.7951.00
503_V507_A0.7951.00
35_G365_E0.7931.00
95_G99_F0.7921.00
275_I287_L0.7921.00
317_T321_T0.7901.00
480_V484_Q0.7901.00
442_A446_Y0.7861.00
351_S355_G0.7821.00
100_F104_L0.7791.00
419_L422_P0.7791.00
463_V467_V0.7791.00
175_L179_T0.7781.00
12_L161_A0.7771.00
313_I398_G0.7761.00
195_G199_F0.7731.00
354_S376_L0.7731.00
296_K300_I0.7731.00
331_Q334_Q0.7721.00
290_L379_Y0.7721.00
349_G512_G0.7701.00
201_A205_A0.7701.00
267_T287_L0.7691.00
392_N444_L0.7691.00
72_N154_H0.7681.00
246_F250_A0.7681.00
78_E81_R0.7661.00
293_Y296_K0.7651.00
264_Y268_N0.7641.00
50_T54_N0.7631.00
245_L249_A0.7611.00
211_V215_Y0.7601.00
288_A291_T0.7591.00
28_I361_F0.7581.00
13_T307_A0.7581.00
151_F216_W0.7571.00
450_M454_H0.7561.00
257_L261_L0.7551.00
476_M479_A0.7541.00
132_R135_S0.7531.00
417_L421_V0.7521.00
16_T20_R0.7511.00
358_Y362_Y0.7491.00
33_M180_F0.7481.00
273_A424_I0.7471.00
381_P385_L0.7471.00
411_I414_V0.7451.00
472_L475_I0.7441.00
6_L10_F0.7421.00
408_S412_G0.7421.00
351_S381_P0.7401.00
483_V486_V0.7371.00
347_V380_S0.7371.00
501_A505_V0.7331.00
404_F407_V0.7331.00
381_P384_I0.7311.00
64_V68_V0.7311.00
294_V376_L0.7301.00
484_Q487_L0.7291.00
434_L437_A0.7281.00
295_Q299_M0.7271.00
474_A478_I0.7251.00
359_T363_G0.7251.00
339_I391_V0.7231.00
437_A441_I0.7221.00
240_K243_F0.7201.00
296_K299_M0.7201.00
71_Y241_M0.7201.00
406_V410_V0.7191.00
345_P473_S0.7191.00
202_L205_A0.7191.00
99_F135_S0.7191.00
339_I387_S0.7151.00
430_D434_L0.7121.00
466_T469_M0.7101.00
103_Y106_A0.7081.00
382_V436_T0.7041.00
270_F429_A0.7011.00
379_Y433_I0.7001.00
240_K244_E0.7001.00
129_Y133_M0.6981.00
382_V385_L0.6981.00
106_A131_I0.6971.00
197_A201_A0.6971.00
335_T391_V0.6961.00
337_Q341_F0.6961.00
60_F87_G0.6951.00
293_Y362_Y0.6951.00
39_G288_A0.6941.00
517_Y521_R0.6941.00
273_A425_K0.6921.00
352_L477_G0.6911.00
131_I135_S0.6911.00
15_G165_V0.6911.00
356_P507_A0.6911.00
251_P402_Q0.6861.00
420_N432_A0.6841.00
68_V84_L0.6811.00
197_A200_A0.6801.00
7_R158_G0.6791.00
262_Y413_V0.6781.00
18_I22_L0.6781.00
448_F452_K0.6781.00
396_L451_I0.6781.00
356_P503_V0.6771.00
85_K226_M0.6771.00
305_A309_G0.6761.00
337_Q465_R0.6751.00
141_V205_A0.6741.00
204_G208_G0.6711.00
499_Q503_V0.6711.00
410_V413_V0.6701.00
96_M139_L0.6691.00
89_S225_A0.6691.00
476_M484_Q0.6661.00
291_T296_K0.6661.00
8_G155_Q0.6631.00
359_T500_A0.6621.00
308_F312_L0.6611.00
450_M453_R0.6591.00
85_K225_A0.6591.00
394_A398_G0.6581.00
46_Y50_T0.6581.00
11_V15_G0.6571.00
441_I445_L0.6561.00
86_A241_M0.6551.00
266_D295_Q0.6541.00
362_Y366_S0.6541.00
346_A349_G0.6541.00
296_K362_Y0.6531.00
168_Q172_I0.6521.00
133_M199_F0.6491.00
402_Q405_A0.6481.00
508_A515_Y0.6461.00
313_I394_A0.6461.00
360_F500_A0.6421.00
287_L291_T0.6401.00
107_P110_A0.6391.00
28_I31_S0.6391.00
70_K321_T0.6381.00
39_G293_Y0.6381.00
208_G212_L0.6381.00
298_V301_P0.6371.00
248_Y252_Y0.6341.00
34_V194_V0.6341.00
392_N451_I0.6321.00
44_Y267_T0.6311.00
359_T370_E0.6311.00
22_L26_Y0.6311.00
178_A181_L0.6271.00
306_T310_L0.6261.00
37_T276_E0.6251.00
394_A397_Q0.6241.00
436_T439_G0.6241.00
297_L362_Y0.6231.00
452_K456_G0.6211.00
106_A109_F0.6211.00
503_V506_I0.6201.00
27_L31_S0.6201.00
133_M137_A0.6191.00
112_I272_K0.6181.00
162_V166_V0.6181.00
311_T314_P0.6171.00
89_S92_L0.6161.00
69_S317_T0.6131.00
133_M198_T0.6121.00
38_G41_L0.6121.00
405_A409_L0.6101.00
364_S370_E0.6091.00
22_L172_I0.6091.00
176_L179_T0.6091.00
175_L200_A0.6091.00
214_I217_N0.6081.00
14_L18_I0.6081.00
350_I357_T0.6051.00
499_Q502_I0.6051.00
353_L508_A0.6051.00
242_F246_F0.6041.00
315_T319_S0.6031.00
433_I437_A0.6021.00
84_L147_V0.6021.00
426_L430_D0.6021.00
86_A239_K0.6011.00
247_S250_A0.5991.00
425_K432_A0.5991.00
386_F390_T0.5981.00
501_A508_A0.5971.00
59_G249_A0.5941.00
67_F83_M0.5921.00
267_T291_T0.5921.00
509_A513_A0.5911.00
212_L215_Y0.5891.00
44_Y47_N0.5871.00
57_T91_M0.5871.00
325_Y328_L0.5861.00
479_A510_V0.5841.00
66_K398_G0.5841.00
82_K85_K0.5841.00
319_S328_L0.5801.00
90_V94_T0.5801.00
66_K402_Q0.5781.00
478_I481_K0.5771.00
182_I193_A0.5761.00
49_Y53_L0.5751.00
252_Y397_Q0.5741.00
49_Y138_L0.5731.00
504_V508_A0.5731.00
471_V475_I0.5721.00
260_P264_Y0.5721.00
346_A350_I0.5711.00
479_A482_I0.5670.99
133_M202_L0.5670.99
475_I478_I0.5670.99
374_N378_W0.5660.99
268_N272_K0.5650.99
88_M91_M0.5650.99
15_G18_I0.5620.99
86_A89_S0.5610.99
30_F175_L0.5610.99
420_N435_A0.5600.99
12_L157_M0.5550.99
359_T373_A0.5540.99
416_K435_A0.5530.99
505_V508_A0.5530.99
514_V518_C0.5530.99
353_L511_G0.5520.99
51_L260_P0.5510.99
8_G311_T0.5500.99
167_E208_G0.5490.99
34_V38_G0.5490.99
290_L295_Q0.5490.99
97_I100_F0.5480.99
9_T13_T0.5480.99
6_L9_T0.5480.99
463_V468_L0.5470.99
183_L193_A0.5470.99
500_A505_V0.5470.99
412_G439_G0.5470.99
86_A90_V0.5460.99
133_M195_G0.5460.99
85_K88_M0.5460.99
440_Y444_L0.5430.99
205_A209_L0.5430.99
341_F345_P0.5430.99
166_V211_V0.5430.99
480_V507_A0.5430.99
65_S69_S0.5420.99
345_P476_M0.5420.99
510_V513_A0.5410.99
83_M245_L0.5400.99
471_V474_A0.5400.99
71_Y80_S0.5390.99
53_L57_T0.5390.99
209_L213_Y0.5370.99
519_G522_L0.5370.99
137_A141_V0.5360.99
274_M424_I0.5360.99
64_V83_M0.5350.99
418_V425_K0.5350.99
517_Y520_Y0.5340.99
172_I175_L0.5330.99
255_V258_A0.5320.99
217_N221_G0.5320.99
504_V507_A0.5320.99
152_Q160_T0.5310.99
506_I509_A0.5300.99
382_V440_Y0.5280.99
80_S84_L0.5280.99
274_M428_Q0.5280.99
41_L130_V0.5270.99
26_Y175_L0.5270.99
339_I343_I0.5270.99
507_A510_V0.5260.99
480_V483_V0.5260.99
48_Q52_F0.5260.99
258_A262_Y0.5250.99
354_S380_S0.5250.99
500_A504_V0.5240.99
340_L384_I0.5240.99
244_E248_Y0.5230.99
36_A366_S0.5200.99
12_L16_T0.5200.99
401_K405_A0.5190.99
102_L131_I0.5180.99
212_L216_W0.5170.99
202_L206_F0.5170.99
328_L331_Q0.5120.99
376_L380_S0.5120.99
423_L431_G0.5110.99
169_I173_I0.5110.99
307_A310_L0.5100.99
77_Y80_S0.5100.99
67_F245_L0.5100.99
484_Q503_V0.5100.99
316_I395_I0.5100.99
161_A164_Q0.5090.99
91_M142_P0.5090.99
159_P162_V0.5080.99
170_V175_L0.5070.99
84_L87_G0.5070.99
348_V351_S0.5070.99
382_V386_F0.5050.99
444_L448_F0.5040.99
16_T307_A0.5040.99
138_L142_P0.5020.99
320_F325_Y0.5010.99
255_V409_L0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4lz6A 1 0.796 100 0.388 Contact Map
3w4tA 1 0.7831 100 0.411 Contact Map
4humA 1 0.818 100 0.415 Contact Map
3mktA 1 0.8143 100 0.425 Contact Map
2cfqA 1 0.7224 32.1 0.952 Contact Map
4n7wA 2 0.3548 13.9 0.96 Contact Map
3wdoA 1 0.7316 11.7 0.961 Contact Map
3zuxA 1 0.3474 11 0.961 Contact Map
2kluA 1 0.0956 8.2 0.964 Contact Map
1pw4A 1 0.3603 7.7 0.964 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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