UXAA - BACSU - GREMLIN Contacts

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UXAA - Altronate dehydratase

UniProt:	O34673	Sequences: MKSFIKIHKQDNVLLALRDIQKGERLHAYGVSIEVKDDIKRGHKIALQSIKENDSIVKYGFPIGHASQDISIGEHIHVHNTKTNLSDIQLYSYTPRFDENPYSNENRTFKGFRRENGDAGVRNELWIVPTVGCVNGIAEKMLQRFVRETGDIAPFDNVLVLKHQYGCSQLGDDHENTKQILLNAIRHPNAGGVLVLGLGCENNELARMKEALQDVNLKRVKFLESQSVTDEMEAGVALLKEIHEAAKGDKREDIPLSELKIGLKCGGSDGFSGITANPLLGRFSDYLIAQGGSTVLTEVPEMFGAETILMQRAANEEVFHKIVDLINDFKQYFIKHDQPVYENPSPGNKAGGISTLEDKSLGCTQKAGISPVTDVLKYGEVLKTKGLTLLSAPGNDLIASSALAAAGCQIVLFTTGRGTPFGTFVPTVKVATNTELYEAKPHWIDFNAGLLAEDDVHEEYVLREFIHYMIEVASGQLVNHEKNDFKELAIFKSGVTL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	497 (484)
Sequences:	1521 (944)
Seq/√Len:	42.9

ECOLI - UXAA GARD
BACSU - UXAA GARD
SULSO - Q97YR2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
471_E	476_Q	6.146	1.00
113_R	258_E	4.939	1.00
110_K	253_D	4.849	1.00
280_L	414_T	3.999	1.00
256_L	470_I	3.855	1.00
113_R	252_E	3.817	1.00
315_N	318_V	3.813	1.00
284_S	294_T	3.790	1.00
316_E	320_H	3.539	1.00
113_R	254_I	3.491	1.00
20_I	35_V	3.438	1.00
66_A	70_I	3.390	1.00
446_F	465_F	3.319	1.00
14_L	47_L	3.192	1.00
295_V	408_C	3.128	1.00
279_L	465_F	3.117	1.00
49_S	72_I	3.109	1.00
320_H	324_D	2.918	1.00
37_D	74_E	2.900	1.00
258_E	385_K	2.881	1.00
392_A	406_A	2.868	1.00
447_N	453_E	2.828	1.00
51_K	54_D	2.824	1.00
479_N	482_K	2.823	1.00
141_M	235_G	2.771	1.00
434_T	438_E	2.682	1.00
191_G	246_A	2.672	1.00
52_E	69_D	2.659	1.00
51_K	69_D	2.620	1.00
56_I	81_T	2.540	1.00
468_Y	476_Q	2.511	1.00
293_S	388_T	2.498	1.00
450_L	464_E	2.423	1.00
35_V	45_I	2.402	1.00
49_S	71_S	2.387	1.00
467_H	471_E	2.372	1.00
331_Q	335_K	2.358	1.00
431_A	444_I	2.349	1.00
119_A	254_I	2.344	1.00
71_S	74_E	2.322	1.00
107_R	467_H	2.274	1.00
22_K	38_D	2.244	1.00
112_F	120_G	2.233	1.00
254_I	258_E	2.219	1.00
46_A	70_I	2.188	1.00
451_L	458_E	2.088	0.99
412_L	430_V	2.071	0.99
461_V	464_E	2.068	0.99
65_H	84_N	2.066	0.99
192_G	242_I	2.052	0.99
404_A	425_V	2.038	0.99
314_A	373_T	2.028	0.99
428_V	472_V	2.026	0.99
321_K	374_D	1.995	0.99
21_Q	38_D	1.974	0.99
50_I	66_A	1.965	0.99
245_A	248_G	1.958	0.99
234_A	237_A	1.945	0.99
18_R	24_E	1.939	0.99
126_W	190_A	1.924	0.99
16_A	20_I	1.910	0.99
286_Y	463_R	1.898	0.99
50_I	70_I	1.893	0.99
373_T	384_T	1.892	0.99
447_N	450_L	1.883	0.99
279_L	451_L	1.880	0.99
154_P	247_K	1.879	0.99
404_A	423_T	1.835	0.98
122_R	481_E	1.814	0.98
430_V	448_A	1.804	0.98
468_Y	471_E	1.802	0.98
12_N	50_I	1.796	0.98
107_R	470_I	1.794	0.98
287_L	292_G	1.785	0.98
121_V	409_Q	1.782	0.98
262_G	411_V	1.779	0.98
434_T	447_N	1.773	0.98
313_A	322_I	1.763	0.98
50_I	54_D	1.750	0.98
450_L	461_V	1.728	0.98
138_A	196_L	1.725	0.98
35_V	39_I	1.705	0.97
141_M	232_M	1.700	0.97
108_T	253_D	1.690	0.97
49_S	69_D	1.688	0.97
12_N	48_Q	1.686	0.97
21_Q	24_E	1.686	0.97
314_A	371_P	1.683	0.97
314_A	384_T	1.680	0.97
434_T	449_G	1.678	0.97
36_K	71_S	1.673	0.97
125_L	239_L	1.671	0.97
435_E	439_A	1.669	0.97
279_L	446_F	1.669	0.97
457_H	460_Y	1.662	0.97
133_C	200_C	1.639	0.97
133_C	167_C	1.639	0.97
327_N	330_K	1.635	0.97
20_I	45_I	1.626	0.97
468_Y	472_V	1.625	0.97
4_F	14_L	1.625	0.97
435_E	438_E	1.621	0.97
410_I	469_M	1.621	0.97
261_I	283_F	1.591	0.96
110_K	476_Q	1.588	0.96
282_R	459_E	1.587	0.96
167_C	200_C	1.551	0.96
129_P	138_A	1.533	0.95
397_L	421_F	1.531	0.95
314_A	318_V	1.531	0.95
400_S	423_T	1.528	0.95
144_R	236_V	1.515	0.95
463_R	467_H	1.505	0.95
431_A	437_Y	1.504	0.95
374_D	384_T	1.504	0.95
245_A	249_D	1.502	0.95
68_Q	74_E	1.469	0.94
36_K	74_E	1.465	0.94
376_L	388_T	1.453	0.94
185_I	208_M	1.450	0.94
125_L	246_A	1.446	0.93
48_Q	54_D	1.445	0.93
286_Y	462_L	1.432	0.93
437_Y	444_I	1.409	0.93
423_T	427_T	1.399	0.92
446_F	468_Y	1.397	0.92
264_K	297_T	1.396	0.92
438_E	441_P	1.392	0.92
118_D	381_V	1.390	0.92
279_L	462_L	1.388	0.92
290_Q	466_I	1.386	0.92
264_K	403_L	1.377	0.92
286_Y	466_I	1.345	0.91
61_F	308_I	1.328	0.90
428_V	468_Y	1.326	0.90
283_F	465_F	1.324	0.90
19_D	41_R	1.323	0.90
141_M	196_L	1.321	0.90
259_L	473_A	1.312	0.90
295_V	382_L	1.312	0.90
15_L	58_K	1.308	0.89
255_P	258_E	1.301	0.89
282_R	458_E	1.298	0.89
377_K	380_E	1.294	0.89
437_Y	447_N	1.287	0.89
19_D	38_D	1.279	0.88
322_I	389_L	1.273	0.88
225_S	231_E	1.271	0.88
374_D	388_T	1.263	0.88
283_F	469_M	1.259	0.88
168_S	202_N	1.251	0.87
237_A	241_E	1.250	0.87
178_K	203_N	1.239	0.87
321_K	380_E	1.238	0.87
171_G	174_H	1.234	0.87
12_N	57_V	1.233	0.86
109_F	119_A	1.224	0.86
81_T	354_S	1.223	0.86
233_E	237_A	1.220	0.86
283_F	287_L	1.218	0.86
67_S	82_K	1.212	0.86
331_Q	334_I	1.208	0.85
121_V	410_I	1.208	0.85
108_T	255_P	1.206	0.85
109_F	474_S	1.204	0.85
243_H	247_K	1.202	0.85
25_R	34_E	1.202	0.85
41_R	435_E	1.193	0.85
185_I	195_V	1.192	0.85
52_E	68_Q	1.189	0.84
14_L	45_I	1.186	0.84
297_T	403_L	1.180	0.84
441_P	479_N	1.169	0.83
107_R	256_L	1.160	0.83
115_E	216_N	1.160	0.83
234_A	238_L	1.159	0.83
133_C	198_L	1.148	0.82
187_H	409_Q	1.132	0.81
124_E	157_N	1.127	0.81
345_S	356_L	1.123	0.81
90_L	93_Y	1.122	0.81
305_A	361_L	1.122	0.81
448_A	461_V	1.120	0.81
27_H	32_S	1.113	0.80
450_L	455_D	1.109	0.80
392_A	402_A	1.109	0.80
107_R	466_I	1.108	0.80
264_K	400_S	1.107	0.80
113_R	119_A	1.105	0.80
370_S	373_T	1.104	0.80
263_L	296_L	1.095	0.79
262_G	284_S	1.093	0.79
167_C	198_L	1.093	0.79
263_L	280_L	1.093	0.79
24_E	35_V	1.093	0.79
136_G	139_E	1.090	0.79
6_K	14_L	1.076	0.78
437_Y	441_P	1.076	0.78
37_D	75_H	1.073	0.78
168_S	395_N	1.072	0.78
420_P	485_F	1.069	0.77
458_E	462_L	1.067	0.77
186_R	381_V	1.065	0.77
78_V	358_D	1.061	0.77
289_A	370_S	1.053	0.76
55_S	62_P	1.051	0.76
318_V	374_D	1.050	0.76
173_D	176_N	1.046	0.76
46_A	50_I	1.037	0.75
230_D	233_E	1.035	0.75
55_S	84_N	1.032	0.75
247_K	250_K	1.026	0.74
279_L	461_V	1.023	0.74
305_A	364_T	1.022	0.74
171_G	177_T	1.020	0.74
110_K	113_R	1.018	0.74
25_R	32_S	1.018	0.74
372_V	389_L	1.013	0.74
70_I	76_I	1.009	0.73
109_F	473_A	1.008	0.73
118_D	260_K	1.001	0.73
324_D	328_D	0.999	0.72
320_H	327_N	0.999	0.72
35_V	38_D	0.997	0.72
168_S	346_P	0.995	0.72
465_F	468_Y	0.994	0.72
227_S	231_E	0.994	0.72
313_A	318_V	0.993	0.72
229_T	442_H	0.993	0.72
434_T	453_E	0.986	0.71
308_I	361_L	0.986	0.71
168_S	345_S	0.978	0.71
6_K	47_L	0.976	0.71
141_M	239_L	0.976	0.71
105_E	463_R	0.973	0.70
109_F	259_L	0.968	0.70
110_K	250_K	0.968	0.70
118_D	258_E	0.964	0.70
55_S	65_H	0.960	0.69
125_L	142_L	0.954	0.69
412_L	469_M	0.951	0.69
283_F	462_L	0.949	0.69
353_I	446_F	0.949	0.69
177_T	490_I	0.949	0.69
406_A	432_T	0.942	0.68
194_L	238_L	0.942	0.68
400_S	411_V	0.939	0.68
171_G	176_N	0.934	0.67
207_R	210_E	0.930	0.67
302_M	372_V	0.930	0.67
174_H	177_T	0.929	0.67
130_T	197_G	0.927	0.67
51_K	71_S	0.921	0.66
125_L	243_H	0.917	0.66
164_Q	489_A	0.916	0.66
451_L	461_V	0.916	0.66
260_K	385_K	0.915	0.66
77_H	354_S	0.914	0.66
338_Q	356_L	0.913	0.65
374_D	382_L	0.908	0.65
4_F	35_V	0.907	0.65
356_L	363_C	0.903	0.65
478_V	481_E	0.902	0.65
92_S	95_P	0.902	0.65
93_Y	323_V	0.901	0.64
6_K	31_V	0.899	0.64
180_I	379_G	0.899	0.64
283_F	412_L	0.899	0.64
182_L	212_L	0.896	0.64
19_D	40_K	0.893	0.64
282_R	369_I	0.892	0.64
143_Q	147_R	0.892	0.64
279_L	283_F	0.890	0.63
327_N	331_Q	0.886	0.63
305_A	344_P	0.885	0.63
93_Y	319_F	0.882	0.63
131_V	167_C	0.877	0.62
282_R	462_L	0.876	0.62
107_R	290_Q	0.875	0.62
275_T	452_A	0.873	0.62
401_S	488_L	0.871	0.62
121_V	474_S	0.868	0.62
264_K	399_A	0.868	0.62
205_L	209_K	0.866	0.61
83_T	339_P	0.863	0.61
208_M	212_L	0.863	0.61
267_G	396_D	0.862	0.61
462_L	465_F	0.861	0.61
90_L	99_E	0.860	0.61
238_L	241_E	0.860	0.61
112_F	249_D	0.859	0.61
317_E	321_K	0.854	0.60
129_P	160_V	0.853	0.60
310_M	323_V	0.850	0.60
61_F	361_L	0.849	0.60
76_I	81_T	0.847	0.60
434_T	437_Y	0.845	0.59
180_I	183_N	0.842	0.59
256_L	466_I	0.842	0.59
173_D	177_T	0.839	0.59
191_G	249_D	0.838	0.59
261_I	469_M	0.835	0.59
377_K	391_S	0.827	0.58
22_K	35_V	0.826	0.58
280_L	412_L	0.826	0.58
4_F	45_I	0.825	0.58
56_I	65_H	0.824	0.57
154_P	250_K	0.821	0.57
252_E	258_E	0.818	0.57
411_V	425_V	0.816	0.57
432_T	451_L	0.815	0.57
302_M	389_L	0.813	0.56
100_N	371_P	0.813	0.56
167_C	199_G	0.813	0.56
261_I	410_I	0.812	0.56
316_E	319_F	0.810	0.56
133_C	199_G	0.810	0.56
477_L	482_K	0.809	0.56
127_I	142_L	0.809	0.56
399_A	408_C	0.809	0.56
45_I	48_Q	0.807	0.56
178_K	211_A	0.804	0.56
154_P	243_H	0.803	0.56
364_T	372_V	0.803	0.56
128_V	185_I	0.803	0.56
408_C	424_F	0.802	0.55
152_I	155_F	0.798	0.55
170_L	202_N	0.794	0.55
110_K	254_I	0.794	0.55
263_L	370_S	0.792	0.54
293_S	382_L	0.791	0.54
133_C	223_L	0.791	0.54
184_A	424_F	0.790	0.54
131_V	200_C	0.789	0.54
438_E	447_N	0.789	0.54
400_S	421_F	0.789	0.54
169_Q	177_T	0.787	0.54
280_L	465_F	0.785	0.54
37_D	45_I	0.785	0.54
271_F	452_A	0.783	0.54
192_G	487_E	0.783	0.54
253_D	470_I	0.781	0.53
179_Q	380_E	0.779	0.53
9_K	50_I	0.779	0.53
48_Q	51_K	0.773	0.53
10_Q	60_G	0.768	0.52
376_L	382_L	0.767	0.52
18_R	21_Q	0.766	0.52
228_V	234_A	0.765	0.52
185_I	220_V	0.764	0.52
347_G	396_D	0.760	0.51
351_G	417_R	0.759	0.51
21_Q	35_V	0.752	0.51
176_N	493_S	0.751	0.51
229_T	233_E	0.750	0.51
141_M	236_V	0.750	0.51
437_Y	449_G	0.749	0.50
167_C	223_L	0.742	0.50
462_L	466_I	0.742	0.50
200_C	223_L	0.739	0.49
329_F	395_N	0.738	0.49
235_G	487_E	0.738	0.49
102_Y	106_N	0.738	0.49
396_D	419_T	0.738	0.49
56_I	68_Q	0.734	0.49
246_A	249_D	0.732	0.49
284_S	370_S	0.731	0.49
286_Y	289_A	0.729	0.49
139_E	162_K	0.728	0.48
56_I	66_A	0.728	0.48
467_H	470_I	0.727	0.48
344_P	349_K	0.727	0.48
345_S	395_N	0.726	0.48
263_L	294_T	0.721	0.48
65_H	86_S	0.721	0.48
264_K	421_F	0.720	0.48
106_N	255_P	0.720	0.48
37_D	68_Q	0.717	0.47
91_Y	96_R	0.717	0.47
446_F	461_V	0.717	0.47
151_D	154_P	0.717	0.47
131_V	198_L	0.714	0.47
300_P	340_V	0.713	0.47
109_F	254_I	0.712	0.47
142_L	158_V	0.711	0.47
22_K	51_K	0.711	0.47
68_Q	79_H	0.710	0.47
454_D	457_H	0.708	0.47
192_G	195_V	0.708	0.47
297_T	392_A	0.705	0.46
328_D	391_S	0.705	0.46
77_H	80_N	0.704	0.46
18_R	26_L	0.704	0.46
374_D	383_K	0.703	0.46
210_E	467_H	0.703	0.46
321_K	324_D	0.701	0.46
48_Q	52_E	0.699	0.46
152_I	247_K	0.697	0.45
279_L	458_E	0.696	0.45
182_L	186_R	0.695	0.45
279_L	448_A	0.695	0.45
18_R	52_E	0.694	0.45
118_D	385_K	0.693	0.45
303_F	330_K	0.692	0.45
9_K	116_N	0.692	0.45
187_H	489_A	0.690	0.45
61_F	307_T	0.689	0.45
78_V	81_T	0.688	0.45
150_G	154_P	0.688	0.45
340_V	356_L	0.684	0.44
21_Q	47_L	0.683	0.44
36_K	49_S	0.683	0.44
50_I	72_I	0.683	0.44
310_M	326_I	0.682	0.44
378_Y	402_A	0.681	0.44
62_P	65_H	0.680	0.44
364_T	399_A	0.679	0.44
93_Y	96_R	0.679	0.44
275_T	454_D	0.678	0.44
282_R	287_L	0.678	0.44
431_A	436_L	0.677	0.44
12_N	81_T	0.676	0.44
450_L	454_D	0.676	0.44
6_K	49_S	0.676	0.44
246_A	484_D	0.676	0.44
139_E	143_Q	0.675	0.43
33_I	45_I	0.675	0.43
307_T	311_Q	0.675	0.43
218_K	241_E	0.671	0.43
22_K	36_K	0.671	0.43
271_F	275_T	0.670	0.43
169_Q	173_D	0.670	0.43
202_N	356_L	0.670	0.43
220_V	231_E	0.668	0.43
39_I	45_I	0.667	0.43
358_D	361_L	0.667	0.43
46_A	66_A	0.665	0.43
113_R	385_K	0.665	0.43
142_L	160_V	0.664	0.42
121_V	473_A	0.663	0.42
175_E	211_A	0.662	0.42
285_D	370_S	0.659	0.42
333_F	340_V	0.658	0.42
90_L	323_V	0.656	0.42
173_D	492_K	0.656	0.42
126_W	319_F	0.656	0.42
54_D	66_A	0.656	0.42
20_I	24_E	0.656	0.42
17_L	188_P	0.656	0.42
436_L	444_I	0.654	0.41
330_K	340_V	0.653	0.41
126_W	159_L	0.652	0.41
9_K	12_N	0.652	0.41
33_I	72_I	0.652	0.41
196_L	223_L	0.651	0.41
467_H	476_Q	0.650	0.41
367_A	387_L	0.650	0.41
181_L	208_M	0.649	0.41
161_L	243_H	0.649	0.41
223_L	226_Q	0.649	0.41
187_H	432_T	0.648	0.41
285_D	369_I	0.648	0.41
83_T	344_P	0.647	0.41
202_N	338_Q	0.645	0.41
190_A	193_V	0.645	0.41
46_A	81_T	0.645	0.41
5_I	17_L	0.644	0.41
153_A	247_K	0.644	0.41
16_A	45_I	0.643	0.40
139_E	334_I	0.643	0.40
253_D	256_L	0.643	0.40
315_N	467_H	0.642	0.40
333_F	440_K	0.641	0.40
121_V	363_C	0.641	0.40
460_Y	463_R	0.640	0.40
329_F	333_F	0.639	0.40
239_L	243_H	0.639	0.40
387_L	446_F	0.638	0.40
198_L	223_L	0.637	0.40
431_A	434_T	0.637	0.40
39_I	119_A	0.637	0.40
103_S	106_N	0.636	0.40
32_S	54_D	0.635	0.40
91_Y	94_T	0.635	0.40
21_Q	36_K	0.634	0.40
293_S	392_A	0.633	0.40
21_Q	96_R	0.633	0.40
10_Q	25_R	0.632	0.39
159_L	486_K	0.632	0.39
225_S	234_A	0.632	0.39
81_T	96_R	0.631	0.39
268_S	353_I	0.631	0.39
132_G	356_L	0.628	0.39
213_Q	216_N	0.628	0.39
394_G	402_A	0.627	0.39
177_T	363_C	0.626	0.39
140_K	143_Q	0.625	0.39
194_L	235_G	0.625	0.39
464_E	479_N	0.623	0.39
119_A	287_L	0.623	0.39
56_I	70_I	0.623	0.39
111_G	254_I	0.620	0.38
69_D	74_E	0.620	0.38
125_L	192_G	0.617	0.38
463_R	466_I	0.616	0.38
24_E	38_D	0.616	0.38
96_R	311_Q	0.616	0.38
249_D	252_E	0.615	0.38
163_H	264_K	0.614	0.38
402_A	490_I	0.614	0.38
180_I	405_A	0.614	0.38
48_Q	72_I	0.613	0.38
41_R	271_F	0.612	0.38
121_V	431_A	0.611	0.38
48_Q	192_G	0.611	0.38
479_N	483_N	0.611	0.38
78_V	354_S	0.610	0.37
228_V	232_M	0.609	0.37
20_I	51_K	0.609	0.37
4_F	24_E	0.609	0.37
293_S	374_D	0.607	0.37
127_I	212_L	0.606	0.37
455_D	460_Y	0.606	0.37
480_H	483_N	0.605	0.37
404_A	411_V	0.604	0.37
292_G	410_I	0.603	0.37
150_G	155_F	0.603	0.37
422_G	487_E	0.602	0.37
69_D	72_I	0.601	0.37
91_Y	323_V	0.601	0.37
62_P	84_N	0.600	0.37
180_I	402_A	0.600	0.37
260_K	382_L	0.600	0.37
338_Q	341_Y	0.599	0.37
184_A	404_A	0.598	0.36
286_Y	290_Q	0.598	0.36
4_F	47_L	0.598	0.36
421_F	427_T	0.598	0.36
33_I	47_L	0.597	0.36
15_L	45_I	0.597	0.36
49_S	315_N	0.597	0.36
305_A	308_I	0.597	0.36
26_L	33_I	0.596	0.36
390_L	400_S	0.596	0.36
319_F	323_V	0.596	0.36
397_L	419_T	0.596	0.36
49_S	96_R	0.595	0.36
340_V	495_V	0.595	0.36
191_G	242_I	0.594	0.36
35_V	40_K	0.593	0.36
161_L	190_A	0.592	0.36
260_K	408_C	0.588	0.36
94_T	98_D	0.587	0.35
288_I	293_S	0.587	0.35
187_H	297_T	0.586	0.35
20_I	196_L	0.585	0.35
250_K	447_N	0.585	0.35
4_F	26_L	0.584	0.35
168_S	363_C	0.583	0.35
36_K	72_I	0.583	0.35
54_D	379_G	0.582	0.35
411_V	423_T	0.581	0.35
321_K	377_K	0.581	0.35
419_T	490_I	0.580	0.35
128_V	187_H	0.579	0.35
36_K	47_L	0.579	0.35
297_T	399_A	0.579	0.35
126_W	424_F	0.578	0.35
254_I	409_Q	0.578	0.35
109_F	470_I	0.577	0.35
279_L	286_Y	0.577	0.35
343_N	356_L	0.576	0.35
202_N	346_P	0.576	0.35
295_V	403_L	0.575	0.34
131_V	343_N	0.574	0.34
428_V	478_V	0.574	0.34
91_Y	319_F	0.573	0.34
6_K	12_N	0.573	0.34
170_L	339_P	0.572	0.34
51_K	210_E	0.570	0.34
333_F	356_L	0.569	0.34
15_L	41_R	0.568	0.34
4_F	81_T	0.567	0.34
223_L	238_L	0.566	0.34
83_T	357_E	0.564	0.33
5_I	39_I	0.563	0.33
91_Y	327_N	0.563	0.33
458_E	461_V	0.562	0.33
9_K	35_V	0.562	0.33
444_I	478_V	0.561	0.33
185_I	193_V	0.560	0.33
191_G	195_V	0.560	0.33
120_G	188_P	0.559	0.33
440_K	443_W	0.558	0.33
39_I	102_Y	0.558	0.33
24_E	315_N	0.558	0.33
21_Q	52_E	0.558	0.33
191_G	194_L	0.558	0.33
197_G	358_D	0.557	0.33
62_P	447_N	0.557	0.33
90_L	98_D	0.557	0.33
22_K	54_D	0.557	0.33
75_H	79_H	0.556	0.33
430_V	472_V	0.556	0.33
134_V	356_L	0.556	0.33
103_S	107_R	0.556	0.33
373_T	376_L	0.555	0.33
378_Y	399_A	0.555	0.33
432_T	452_A	0.555	0.33
182_L	211_A	0.554	0.33
302_M	325_L	0.554	0.33
271_F	432_T	0.554	0.33
12_N	84_N	0.553	0.33
6_K	99_E	0.553	0.33
195_V	208_M	0.552	0.32
75_H	78_V	0.551	0.32
252_E	467_H	0.550	0.32
297_T	400_S	0.550	0.32
342_E	495_V	0.549	0.32
367_A	399_A	0.549	0.32
243_H	353_I	0.548	0.32
318_V	385_K	0.548	0.32
312_R	387_L	0.547	0.32
27_H	97_F	0.547	0.32
26_L	35_V	0.547	0.32
69_D	437_Y	0.546	0.32
395_N	495_V	0.546	0.32
380_E	383_K	0.544	0.32
21_Q	68_Q	0.544	0.32
129_P	162_K	0.544	0.32
12_N	19_D	0.543	0.32
158_V	243_H	0.543	0.32
87_D	340_V	0.541	0.32
5_I	59_Y	0.541	0.32
32_S	94_T	0.541	0.32
47_L	72_I	0.541	0.32
308_I	365_Q	0.540	0.31
143_Q	411_V	0.540	0.31
107_R	286_Y	0.540	0.31
308_I	364_T	0.539	0.31
128_V	208_M	0.539	0.31
175_E	179_Q	0.539	0.31
271_F	449_G	0.537	0.31
313_A	380_E	0.537	0.31
197_G	487_E	0.536	0.31
358_D	422_G	0.536	0.31
382_L	388_T	0.536	0.31
325_L	377_K	0.535	0.31
71_S	99_E	0.534	0.31
22_K	37_D	0.534	0.31
109_F	246_A	0.533	0.31
283_F	294_T	0.533	0.31
468_Y	478_V	0.533	0.31
196_L	235_G	0.533	0.31
232_M	399_A	0.532	0.31
152_I	243_H	0.532	0.31
276_A	414_T	0.531	0.31
172_D	177_T	0.531	0.31
128_V	181_L	0.530	0.31
85_L	95_P	0.530	0.31
14_L	98_D	0.530	0.31
332_Y	349_K	0.527	0.30
435_E	453_E	0.527	0.30
31_V	47_L	0.526	0.30
56_I	103_S	0.526	0.30
282_R	463_R	0.525	0.30
4_F	57_V	0.524	0.30
395_N	419_T	0.524	0.30
133_C	417_R	0.524	0.30
261_I	403_L	0.523	0.30
180_I	401_S	0.522	0.30
10_Q	34_E	0.522	0.30
10_Q	22_K	0.522	0.30
339_P	420_P	0.522	0.30
10_Q	48_Q	0.521	0.30
21_Q	99_E	0.520	0.30
376_L	406_A	0.520	0.30
275_T	455_D	0.520	0.30
295_V	390_L	0.519	0.30
274_I	450_L	0.519	0.30
379_G	457_H	0.519	0.30
422_G	486_K	0.519	0.30
111_G	182_L	0.518	0.30
99_E	457_H	0.518	0.30
182_L	255_P	0.518	0.30
5_I	36_K	0.517	0.30
119_A	247_K	0.517	0.30
202_N	349_K	0.517	0.30
419_T	443_W	0.516	0.30
347_G	417_R	0.516	0.30
183_N	187_H	0.516	0.30
141_M	194_L	0.515	0.29
170_L	420_P	0.514	0.29
116_N	409_Q	0.514	0.29
10_Q	71_S	0.514	0.29
163_H	177_T	0.513	0.29
157_N	478_V	0.513	0.29
5_I	271_F	0.513	0.29
168_S	343_N	0.512	0.29
109_F	255_P	0.512	0.29
381_V	406_A	0.512	0.29
175_E	207_R	0.511	0.29
65_H	82_K	0.511	0.29
91_Y	95_P	0.511	0.29
70_I	80_N	0.510	0.29
347_G	394_G	0.510	0.29
25_R	56_I	0.509	0.29
67_S	78_V	0.509	0.29
119_A	252_E	0.508	0.29
398_I	485_F	0.508	0.29
419_T	487_E	0.507	0.29
102_Y	105_E	0.506	0.29
141_M	260_K	0.506	0.29
9_K	385_K	0.505	0.29
6_K	10_Q	0.505	0.29
19_D	99_E	0.505	0.29
15_L	20_I	0.505	0.29
222_F	231_E	0.504	0.29
92_S	311_Q	0.503	0.29
232_M	458_E	0.502	0.28
174_H	203_N	0.502	0.28
420_P	440_K	0.501	0.28
379_G	406_A	0.501	0.28
198_L	417_R	0.501	0.28
202_N	222_F	0.501	0.28
26_L	57_V	0.500	0.28

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3k3sA	2	0.171	100	0.845	Contact Map
3lazA	2	0.165	100	0.853	Contact Map
1ucsA	1	0.1268	75	0.979	Contact Map
1msiA	1	0.1308	71	0.979	Contact Map
1vliA	2	0.171	70.6	0.979	Contact Map
1c89A	1	0.171	70.6	0.979	Contact Map
4ur6A	2	0.1268	70.3	0.98	Contact Map
1wiwA	2	0.3219	67.6	0.98	Contact Map
3teeA	1	0.2636	67.1	0.98	Contact Map
3frnA	1	0.2535	64.7	0.98	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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