HISX - BACSU - GREMLIN Contacts

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HISX - Histidinol dehydrogenase

UniProt:	O34651	Sequences: MKIKTISGAERLSLKRSIDAGTEEQRKTVRSIIEDVKANGDQAVRSYTAKFDCIEIDSPLVTKEEFEEAYTSLDSRLLQVIRQAIENIREYHERQLQSSWFYHRKDGTMLGQKVTALDSAGVYVPGGTAAYPSSVLMNVIPALVAGVERIVLVTPPGKDGLLSPGVLVAAAELGIKDIYKMGGAQAIAALAYGTETIEPVDKITGPGNIYVALAKREVFGDVDIDMIAGPSEIVVLADETAIPSEIAADLLSQAEHDKLSSCVFVTDSMALAETVSAEVNKQLETLPRREIAEASVRDYGCIYVAETMVEAIETVNTLAPEHLEIITQSPEALLGSIKHAGAIFLGRYSPEPVGDYFAGPNHVLPTNGTARFSSPLNVTDFQKKSSIISYSQSAFEEHAESIAAFARLEGLEAHARSIEARERRISK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	427 (411)
Sequences:	3824 (2140)
Seq/√Len:	105.6

ECOLI - HISX
BACSU - HISX
HALSA - HISX
SULSO - HISX

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
35_D	39_N	4.150	1.00
49_A	55_E	4.139	1.00
39_N	46_S	3.575	1.00
60_L	177_D	3.300	1.00
119_S	149_R	3.159	1.00
33_I	188_A	3.143	1.00
128_T	258_K	3.094	1.00
153_V	190_L	3.071	1.00
289_R	293_E	2.974	1.00
244_S	278_E	2.938	1.00
329_S	332_A	2.835	1.00
236_L	315_V	2.785	1.00
88_I	136_L	2.771	1.00
122_V	139_V	2.730	1.00
89_R	93_E	2.709	1.00
331_E	389_S	2.575	1.00
149_R	177_D	2.541	1.00
83_Q	401_S	2.540	1.00
309_V	336_S	2.503	1.00
72_S	164_P	2.500	1.00
269_M	273_E	2.490	1.00
306_E	310_E	2.485	1.00
35_D	47_Y	2.457	1.00
278_E	281_K	2.329	1.00
407_R	419_E	2.323	1.00
70_Y	171_A	2.314	1.00
118_D	338_K	2.270	1.00
143_L	176_K	2.255	1.00
82_R	172_E	2.148	1.00
305_A	311_A	2.144	1.00
66_F	178_I	2.126	1.00
272_A	302_I	2.102	1.00
239_E	268_S	2.073	1.00
272_A	304_V	2.072	1.00
85_I	89_R	2.048	1.00
293_E	297_R	2.042	1.00
46_S	50_K	2.039	1.00
41_D	194_T	2.036	1.00
399_A	422_E	2.024	1.00
407_R	412_E	2.009	1.00
403_A	419_E	2.003	1.00
234_V	315_V	2.001	1.00
213_L	217_E	1.982	1.00
39_N	42_Q	1.964	1.00
85_I	140_I	1.954	1.00
35_D	46_S	1.951	1.00
312_I	337_I	1.946	1.00
201_D	371_R	1.938	1.00
257_D	260_S	1.924	1.00
139_V	175_I	1.921	1.00
28_T	210_Y	1.918	1.00
276_S	302_I	1.916	1.00
31_S	35_D	1.912	1.00
148_E	338_K	1.911	1.00
236_L	311_A	1.872	1.00
67_E	171_A	1.872	1.00
233_I	252_S	1.860	1.00
34_E	38_A	1.860	1.00
67_E	71_T	1.847	1.00
270_A	274_T	1.804	1.00
240_T	328_Q	1.785	1.00
283_L	292_A	1.761	1.00
266_T	272_A	1.755	1.00
118_D	339_H	1.753	1.00
416_R	419_E	1.745	1.00
78_L	82_R	1.741	1.00
287_P	412_E	1.733	1.00
60_L	179_Y	1.712	1.00
118_D	148_E	1.711	1.00
352_P	417_S	1.698	1.00
89_R	143_L	1.685	1.00
392_Q	396_E	1.683	1.00
312_I	333_L	1.643	1.00
353_V	402_I	1.636	1.00
30_R	217_E	1.633	1.00
62_T	65_E	1.630	1.00
63_K	67_E	1.625	1.00
117_L	202_K	1.618	1.00
192_Y	221_D	1.616	1.00
65_E	180_K	1.596	1.00
239_E	267_D	1.582	1.00
325_I	337_I	1.560	1.00
307_T	310_E	1.557	1.00
45_R	59_P	1.551	1.00
152_L	170_A	1.525	1.00
330_P	345_L	1.515	1.00
248_A	282_Q	1.515	1.00
78_L	168_V	1.506	1.00
115_T	385_S	1.497	1.00
267_D	305_A	1.484	1.00
68_E	72_S	1.478	1.00
212_A	227_I	1.474	1.00
77_L	408_L	1.464	1.00
101_F	109_M	1.455	1.00
41_D	196_T	1.448	1.00
70_Y	168_V	1.445	1.00
179_Y	198_E	1.443	1.00
181_M	197_I	1.423	1.00
278_E	282_Q	1.417	1.00
403_A	407_R	1.406	1.00
264_F	275_V	1.403	1.00
85_I	136_L	1.391	1.00
80_V	405_F	1.385	1.00
121_G	190_L	1.382	1.00
136_L	140_I	1.375	1.00
286_L	292_A	1.361	1.00
327_T	333_L	1.360	1.00
75_S	79_Q	1.357	1.00
154_T	162_L	1.352	1.00
97_Q	379_T	1.350	0.99
157_G	161_L	1.350	0.99
239_E	328_Q	1.348	0.99
358_A	388_I	1.345	0.99
244_S	281_K	1.331	0.99
403_A	415_A	1.319	0.99
120_A	202_K	1.316	0.99
135_V	152_L	1.312	0.99
379_T	384_K	1.306	0.99
153_V	186_A	1.295	0.99
26_R	30_R	1.291	0.99
81_I	172_E	1.289	0.99
80_V	404_A	1.289	0.99
64_E	68_E	1.288	0.99
151_V	177_D	1.285	0.99
63_K	171_A	1.284	0.99
274_T	277_A	1.284	0.99
348_Y	392_Q	1.281	0.99
343_I	385_S	1.278	0.99
69_A	167_L	1.276	0.99
168_V	171_A	1.274	0.99
191_A	218_V	1.269	0.99
258_K	294_A	1.262	0.99
326_I	347_R	1.259	0.99
36_V	188_A	1.257	0.99
339_H	383_K	1.254	0.99
294_A	297_R	1.250	0.99
407_R	415_A	1.246	0.99
169_A	173_L	1.244	0.99
26_R	217_E	1.239	0.99
280_N	293_E	1.238	0.99
151_V	190_L	1.236	0.99
192_Y	218_V	1.236	0.99
33_I	221_D	1.233	0.99
234_V	265_V	1.229	0.99
85_I	172_E	1.223	0.99
73_L	78_L	1.208	0.99
236_L	265_V	1.202	0.99
271_L	275_V	1.201	0.99
77_L	165_G	1.199	0.99
240_T	347_R	1.198	0.99
134_S	138_N	1.190	0.99
395_F	418_I	1.190	0.99
209_I	213_L	1.182	0.99
150_I	176_K	1.174	0.99
415_A	419_E	1.173	0.99
128_T	288_R	1.169	0.99
242_I	245_E	1.169	0.99
68_E	161_L	1.155	0.98
61_V	167_L	1.152	0.98
97_Q	382_Q	1.147	0.98
42_Q	195_E	1.144	0.98
284_E	289_R	1.143	0.98
63_K	176_K	1.138	0.98
44_V	181_M	1.137	0.98
202_K	380_D	1.137	0.98
315_V	320_P	1.133	0.98
153_V	181_M	1.128	0.98
30_R	34_E	1.127	0.98
343_I	387_I	1.119	0.98
282_Q	416_R	1.110	0.98
236_L	325_I	1.108	0.98
265_V	314_T	1.107	0.98
33_I	218_V	1.097	0.98
294_A	298_D	1.094	0.98
246_I	275_V	1.088	0.98
265_V	305_A	1.086	0.98
266_T	302_I	1.078	0.98
218_V	222_V	1.078	0.98
241_A	246_I	1.077	0.98
61_V	180_K	1.073	0.97
138_N	363_V	1.072	0.97
251_L	292_A	1.070	0.97
357_F	402_I	1.063	0.97
327_T	330_P	1.062	0.97
115_T	383_K	1.062	0.97
25_Q	213_L	1.060	0.97
244_S	420_A	1.052	0.97
81_I	405_F	1.051	0.97
109_M	389_S	1.050	0.97
27_K	31_S	1.048	0.97
319_A	370_A	1.046	0.97
32_I	184_A	1.046	0.97
357_F	401_S	1.044	0.97
237_A	271_L	1.040	0.97
117_L	120_A	1.038	0.97
122_V	150_I	1.038	0.97
47_Y	51_F	1.027	0.97
243_P	274_T	1.027	0.97
97_Q	114_V	1.026	0.97
269_M	304_V	1.022	0.97
143_L	173_L	1.019	0.97
48_T	185_Q	1.011	0.96
305_A	314_T	1.008	0.96
70_Y	78_L	1.004	0.96
369_T	372_F	1.004	0.96
377_N	384_K	1.002	0.96
236_L	312_I	0.990	0.96
277_A	281_K	0.986	0.96
235_V	250_L	0.985	0.96
93_E	144_V	0.973	0.95
251_L	413_A	0.973	0.95
103_H	106_D	0.969	0.95
61_V	69_A	0.969	0.95
266_T	304_V	0.964	0.95
59_P	181_M	0.960	0.95
117_L	223_D	0.960	0.95
265_V	315_V	0.959	0.95
252_S	352_P	0.954	0.95
353_V	390_Y	0.953	0.95
134_S	363_V	0.950	0.95
233_I	324_E	0.949	0.95
242_I	347_R	0.948	0.95
363_V	376_L	0.945	0.95
94_R	102_Y	0.944	0.95
138_N	204_T	0.939	0.94
37_K	221_D	0.936	0.94
308_M	333_L	0.936	0.94
350_P	417_S	0.935	0.94
81_I	169_A	0.933	0.94
281_K	285_T	0.933	0.94
325_I	345_L	0.931	0.94
33_I	37_K	0.927	0.94
276_S	280_N	0.927	0.94
250_L	264_F	0.925	0.94
33_I	192_Y	0.924	0.94
26_R	213_L	0.922	0.94
79_Q	82_R	0.920	0.94
237_A	241_A	0.919	0.94
28_T	31_S	0.912	0.94
390_Y	398_H	0.912	0.94
32_I	36_V	0.911	0.94
334_L	345_L	0.910	0.94
86_E	89_R	0.910	0.94
29_V	213_L	0.909	0.93
267_D	311_A	0.908	0.93
416_R	420_A	0.907	0.93
402_I	418_I	0.905	0.93
284_E	293_E	0.902	0.93
35_D	50_K	0.899	0.93
395_F	399_A	0.898	0.93
74_D	77_L	0.898	0.93
236_L	308_M	0.892	0.93
96_L	382_Q	0.891	0.93
37_K	192_Y	0.891	0.93
66_F	70_Y	0.889	0.93
248_A	420_A	0.889	0.93
139_V	173_L	0.889	0.93
104_R	108_T	0.889	0.93
42_Q	46_S	0.888	0.93
36_V	184_A	0.886	0.93
246_I	271_L	0.885	0.93
334_L	387_I	0.880	0.92
66_F	171_A	0.877	0.92
67_E	70_Y	0.876	0.92
48_T	56_I	0.868	0.92
39_N	50_K	0.867	0.92
82_R	168_V	0.864	0.92
308_M	311_A	0.863	0.92
77_L	404_A	0.861	0.92
90_E	94_R	0.856	0.91
124_V	152_L	0.854	0.91
100_W	112_Q	0.853	0.91
189_A	197_I	0.853	0.91
76_R	404_A	0.847	0.91
266_T	271_L	0.846	0.91
280_N	284_E	0.843	0.91
342_A	388_I	0.842	0.91
353_V	398_H	0.841	0.91
310_E	313_E	0.841	0.91
284_E	287_P	0.840	0.90
86_E	90_E	0.840	0.90
245_E	347_R	0.840	0.90
80_V	401_S	0.839	0.90
44_V	184_A	0.838	0.90
53_C	159_D	0.838	0.90
118_D	201_D	0.837	0.90
282_Q	420_A	0.835	0.90
290_E	293_E	0.833	0.90
149_R	179_Y	0.833	0.90
213_L	216_R	0.831	0.90
267_D	308_M	0.830	0.90
23_E	30_R	0.830	0.90
23_E	27_K	0.829	0.90
89_R	140_I	0.824	0.90
44_V	189_A	0.822	0.90
375_P	386_S	0.821	0.89
177_D	198_E	0.818	0.89
342_A	386_S	0.813	0.89
337_I	343_I	0.813	0.89
65_E	161_L	0.812	0.89
243_P	275_V	0.810	0.89
100_W	111_G	0.806	0.89
151_V	198_E	0.806	0.89
32_I	47_Y	0.806	0.89
379_T	382_Q	0.801	0.88
135_V	169_A	0.800	0.88
342_A	387_I	0.798	0.88
313_E	316_N	0.797	0.88
44_V	194_T	0.795	0.88
84_A	88_I	0.794	0.88
122_V	138_N	0.794	0.88
393_S	396_E	0.793	0.88
201_D	339_H	0.790	0.88
132_P	405_F	0.790	0.88
334_L	343_I	0.789	0.88
273_E	276_S	0.789	0.88
316_N	336_S	0.787	0.87
92_H	95_Q	0.784	0.87
95_Q	361_N	0.784	0.87
244_S	282_Q	0.781	0.87
396_E	422_E	0.780	0.87
54_I	156_P	0.779	0.87
96_L	144_V	0.779	0.87
45_R	49_A	0.778	0.87
91_Y	360_P	0.777	0.87
244_S	423_R	0.774	0.87
312_I	336_S	0.774	0.87
265_V	311_A	0.771	0.86
151_V	179_Y	0.771	0.86
90_E	93_E	0.770	0.86
250_L	279_V	0.764	0.86
235_V	246_I	0.764	0.86
350_P	395_F	0.764	0.86
87_N	357_F	0.762	0.86
168_V	172_E	0.759	0.85
39_N	43_A	0.759	0.85
41_D	195_E	0.757	0.85
377_N	382_Q	0.756	0.85
406_A	415_A	0.756	0.85
106_D	397_E	0.756	0.85
138_N	376_L	0.756	0.85
179_Y	197_I	0.754	0.85
33_I	217_E	0.752	0.85
130_A	410_G	0.751	0.85
412_E	416_R	0.750	0.85
223_D	372_F	0.749	0.85
203_I	218_V	0.746	0.84
25_Q	209_I	0.746	0.84
156_P	162_L	0.741	0.84
199_P	368_G	0.740	0.84
233_I	262_C	0.740	0.84
84_A	357_F	0.738	0.84
234_V	318_L	0.738	0.84
241_A	271_L	0.736	0.84
62_T	180_K	0.735	0.84
189_A	194_T	0.735	0.84
28_T	50_K	0.735	0.84
342_A	358_A	0.735	0.84
93_E	96_L	0.734	0.83
288_R	291_I	0.734	0.83
60_L	149_R	0.734	0.83
404_A	408_L	0.733	0.83
251_L	283_L	0.733	0.83
24_E	27_K	0.732	0.83
135_V	175_I	0.732	0.83
31_S	34_E	0.729	0.83
31_S	50_K	0.728	0.83
360_P	388_I	0.727	0.83
357_F	398_H	0.727	0.83
376_L	380_D	0.726	0.83
353_V	395_F	0.725	0.83
143_L	175_I	0.725	0.83
328_Q	347_R	0.723	0.83
273_E	277_A	0.722	0.82
390_Y	394_A	0.722	0.82
44_V	48_T	0.720	0.82
149_R	198_E	0.719	0.82
70_Y	172_E	0.719	0.82
312_I	327_T	0.717	0.82
252_S	417_S	0.716	0.82
47_Y	185_Q	0.716	0.82
112_Q	377_N	0.716	0.82
90_E	102_Y	0.713	0.82
209_I	259_L	0.710	0.81
45_R	56_I	0.709	0.81
35_D	38_A	0.704	0.81
194_T	197_I	0.703	0.81
122_V	204_T	0.702	0.81
290_E	294_A	0.702	0.81
45_R	58_S	0.701	0.81
45_R	57_D	0.701	0.81
374_S	384_K	0.699	0.80
239_E	270_A	0.698	0.80
138_N	361_N	0.698	0.80
245_E	326_I	0.697	0.80
49_A	54_I	0.696	0.80
188_A	218_V	0.696	0.80
115_T	338_K	0.694	0.80
203_I	222_V	0.694	0.80
28_T	47_Y	0.694	0.80
114_V	382_Q	0.693	0.80
223_D	373_S	0.690	0.80
399_A	403_A	0.689	0.79
85_I	173_L	0.689	0.79
136_L	169_A	0.688	0.79
82_R	86_E	0.688	0.79
277_A	280_N	0.688	0.79
39_N	47_Y	0.687	0.79
83_Q	357_F	0.687	0.79
86_E	93_E	0.684	0.79
395_F	402_I	0.682	0.79
171_A	178_I	0.682	0.79
60_L	63_K	0.682	0.79
332_A	335_G	0.681	0.79
349_S	390_Y	0.681	0.79
45_R	55_E	0.681	0.79
76_R	400_E	0.678	0.78
25_Q	29_V	0.678	0.78
262_C	300_G	0.678	0.78
129_A	411_L	0.676	0.78
14_L	17_S	0.674	0.78
279_V	296_V	0.674	0.78
286_L	416_R	0.673	0.78
286_L	413_A	0.671	0.78
344_F	354_G	0.671	0.78
407_R	416_R	0.670	0.78
42_Q	45_R	0.667	0.77
241_A	347_R	0.667	0.77
218_V	221_D	0.667	0.77
270_A	273_E	0.667	0.77
48_T	53_C	0.665	0.77
216_R	220_G	0.663	0.77
24_E	28_T	0.662	0.77
121_G	153_V	0.660	0.76
400_E	404_A	0.658	0.76
96_L	99_S	0.655	0.76
243_P	271_L	0.654	0.76
70_Y	167_L	0.654	0.76
271_L	274_T	0.653	0.76
308_M	312_I	0.652	0.76
70_Y	82_R	0.652	0.76
49_A	56_I	0.649	0.75
101_F	331_E	0.649	0.75
251_L	286_L	0.647	0.75
85_I	88_I	0.646	0.75
308_M	315_V	0.644	0.75
27_K	30_R	0.644	0.75
311_A	315_V	0.643	0.75
68_E	71_T	0.642	0.75
330_P	334_L	0.642	0.75
316_N	338_K	0.641	0.74
308_M	327_T	0.641	0.74
252_S	413_A	0.639	0.74
316_N	334_L	0.637	0.74
73_L	168_V	0.635	0.74
60_L	151_V	0.633	0.73
44_V	47_Y	0.633	0.73
340_A	343_I	0.633	0.73
87_N	402_I	0.632	0.73
83_Q	86_E	0.631	0.73
281_K	284_E	0.630	0.73
119_S	201_D	0.628	0.73
236_L	327_T	0.622	0.72
276_S	279_V	0.622	0.72
292_A	296_V	0.621	0.72
130_A	163_S	0.621	0.72
286_L	412_E	0.619	0.72
113_K	335_G	0.618	0.72
65_E	68_E	0.617	0.72
61_V	65_E	0.616	0.71
179_Y	196_T	0.615	0.71
43_A	47_Y	0.615	0.71
283_L	293_E	0.615	0.71
117_L	147_V	0.614	0.71
228_A	361_N	0.613	0.71
267_D	307_T	0.613	0.71
181_M	189_A	0.613	0.71
315_V	337_I	0.613	0.71
99_S	114_V	0.612	0.71
165_G	408_L	0.612	0.71
412_E	419_E	0.612	0.71
220_G	372_F	0.611	0.71
64_E	67_E	0.611	0.71
241_A	326_I	0.609	0.71
200_V	222_V	0.608	0.70
63_K	66_F	0.606	0.70
227_I	373_S	0.604	0.70
320_P	323_L	0.603	0.70
282_Q	286_L	0.601	0.70
122_V	175_I	0.600	0.69
61_V	178_I	0.599	0.69
199_P	221_D	0.597	0.69
72_S	161_L	0.596	0.69
45_R	196_T	0.596	0.69
202_K	223_D	0.593	0.69
128_T	226_M	0.593	0.69
245_E	348_Y	0.588	0.68
309_V	313_E	0.587	0.68
330_P	389_S	0.586	0.68
349_S	388_I	0.585	0.68
122_V	152_L	0.584	0.67
138_N	152_L	0.583	0.67
79_Q	83_Q	0.583	0.67
129_A	288_R	0.582	0.67
21_G	24_E	0.582	0.67
44_V	59_P	0.581	0.67
135_V	173_L	0.581	0.67
312_I	343_I	0.581	0.67
66_F	168_V	0.578	0.67
285_T	416_R	0.578	0.67
101_F	387_I	0.577	0.66
109_M	391_S	0.576	0.66
395_F	422_E	0.574	0.66
245_E	420_A	0.572	0.66
355_D	362_H	0.570	0.66
91_Y	386_S	0.569	0.65
81_I	165_G	0.567	0.65
89_R	144_V	0.567	0.65
15_K	18_I	0.567	0.65
84_A	405_F	0.566	0.65
95_Q	112_Q	0.566	0.65
204_T	363_V	0.565	0.65
61_V	156_P	0.562	0.64
288_R	410_G	0.561	0.64
100_W	113_K	0.560	0.64
81_I	168_V	0.560	0.64
44_V	197_I	0.559	0.64
254_A	262_C	0.559	0.64
253_Q	355_D	0.559	0.64
33_I	44_V	0.555	0.64
344_F	351_E	0.555	0.64
119_S	200_V	0.555	0.64
246_I	326_I	0.555	0.64
119_S	151_V	0.554	0.63
101_F	111_G	0.553	0.63
87_N	104_R	0.553	0.63
317_T	371_R	0.552	0.63
272_A	276_S	0.550	0.63
287_P	292_A	0.548	0.63
156_P	181_M	0.547	0.62
36_V	54_I	0.546	0.62
152_L	175_I	0.544	0.62
32_I	51_F	0.544	0.62
251_L	296_V	0.543	0.62
279_V	284_E	0.543	0.62
33_I	191_A	0.542	0.62
337_I	385_S	0.540	0.61
313_E	317_T	0.540	0.61
324_E	361_N	0.539	0.61
79_Q	401_S	0.539	0.61
391_S	394_A	0.539	0.61
342_A	360_P	0.538	0.61
28_T	36_V	0.537	0.61
131_Y	411_L	0.536	0.61
110_L	342_A	0.536	0.61
69_A	168_V	0.535	0.61
115_T	387_I	0.535	0.61
99_S	113_K	0.534	0.61
117_L	380_D	0.534	0.61
234_V	314_T	0.534	0.61
250_L	262_C	0.533	0.60
46_S	49_A	0.531	0.60
267_D	271_L	0.531	0.60
261_S	318_L	0.531	0.60
295_S	300_G	0.531	0.60
73_L	172_E	0.530	0.60
78_L	172_E	0.530	0.60
394_A	398_H	0.530	0.60
238_D	241_A	0.529	0.60
113_K	385_S	0.529	0.60
154_T	157_G	0.528	0.60
153_V	156_P	0.528	0.60
167_L	178_I	0.528	0.60
204_T	376_L	0.527	0.60
398_H	401_S	0.527	0.60
41_D	189_A	0.525	0.59
216_R	219_F	0.525	0.59
114_V	384_K	0.525	0.59
120_A	204_T	0.524	0.59
278_E	418_I	0.524	0.59
169_A	405_F	0.524	0.59
287_P	407_R	0.522	0.59
167_L	381_F	0.521	0.59
23_E	34_E	0.520	0.59
157_G	160_G	0.520	0.59
126_G	129_A	0.518	0.58
76_R	80_V	0.518	0.58
118_D	316_N	0.518	0.58
403_A	422_E	0.516	0.58
53_C	185_Q	0.515	0.58
230_P	259_L	0.514	0.58
21_G	25_Q	0.514	0.58
36_V	153_V	0.514	0.58
149_R	176_K	0.513	0.58
113_K	387_I	0.513	0.58
112_Q	384_K	0.513	0.58
14_L	301_C	0.512	0.57
216_R	372_F	0.512	0.57
352_P	418_I	0.510	0.57
268_S	271_L	0.509	0.57
94_R	100_W	0.509	0.57
87_N	105_K	0.508	0.57
219_F	373_S	0.508	0.57
77_L	405_F	0.507	0.57
131_Y	212_A	0.506	0.57
350_P	399_A	0.506	0.57
226_M	342_A	0.505	0.56
303_Y	314_T	0.505	0.56
29_V	217_E	0.504	0.56
78_L	171_A	0.504	0.56
266_T	275_V	0.503	0.56
393_S	397_E	0.503	0.56
153_V	179_Y	0.502	0.56
395_F	420_A	0.501	0.56
239_E	274_T	0.501	0.56
29_V	33_I	0.500	0.56

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4g09A	2	0.9859	100	0.017	Contact Map
1kaeA	2	0.9883	100	0.033	Contact Map
4gicA	2	0.8689	100	0.05	Contact Map
3my7A	2	0.7447	98	0.948	Contact Map
4itaA	2	0.7728	98	0.948	Contact Map
4ghkA	3	0.7869	97.9	0.949	Contact Map
4jbeA	2	0.7799	97.7	0.951	Contact Map
1euhA	4	0.7986	97.7	0.951	Contact Map
1o20A	3	0.808	97.7	0.952	Contact Map
4qtoA	4	0.808	97.6	0.952	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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