AGAL - BACSU - GREMLIN Contacts

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AGAL - Alpha-galactosidase

UniProt:	O34645	Sequences: MKKITFIGAGSTIFAKNVLGDCLLTEALNGFEFALYDIDPKRLQESQLMLENLRDRYNPSVAINSYDDRKLALQNAGYVINAIQVGGYKPSTVIDFEIPKRYGLRQTIADTVGIGGIFRSLRTIPVLFDIAKDMEEMCPDAWFLNYTNPMATLTGAMLRYTNIKTIGLCHSVQVCTKDLFKALGMEHDGIEERIAGINHMAWLLEVKKDGTDLYPEIKRRAKEKQKTKHHDMVRFELMDKFGYYVTESSEHNAEYHPYFIKRNYPELISELQIPLDEYPRRCVKQIENWEKMRDDIVNNKNLTHERSKEYGSRIIEAMETNEPFTFGGNVLNTGLITNLPSKAVVEVTCVADRKKITPCFAGELPEQLAALNRTNINTQLMTIEAAVTRKKEAVYQAAMLDPHTSAELSMKDIISMCDDLFAAHGDWLPEYK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	432 (412)
Sequences:	1744 (1031)
Seq/√Len:	50.8

ECOLI - AGAL CHBF GLVG
BACSU - AGAL GLVA LICH LPLD

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
70_K	136_E	5.616	1.00
78_Y	319_E	4.095	1.00
73_L	138_C	3.937	1.00
69_R	133_D	3.750	1.00
101_R	419_D	3.403	1.00
189_G	209_D	3.348	1.00
134_M	143_F	3.337	1.00
134_M	163_I	3.163	1.00
352_D	357_T	3.140	1.00
47_Q	65_S	3.137	1.00
391_K	418_D	3.122	1.00
205_E	212_D	3.078	1.00
317_A	324_F	3.034	1.00
395_Y	417_C	3.034	1.00
68_D	71_L	2.985	1.00
70_K	133_D	2.917	1.00
32_E	62_A	2.825	1.00
32_E	64_N	2.783	1.00
328_G	351_A	2.778	1.00
104_L	416_M	2.739	1.00
337_T	363_E	2.583	1.00
211_T	216_E	2.552	1.00
135_E	161_T	2.541	1.00
47_Q	51_E	2.530	1.00
364_L	372_N	2.449	1.00
186_E	189_G	2.427	1.00
166_I	356_I	2.396	1.00
335_L	345_V	2.377	1.00
3_K	34_A	2.352	1.00
394_V	417_C	2.303	1.00
208_K	213_L	2.299	1.00
85_V	126_V	2.261	1.00
132_K	135_E	2.261	1.00
34_A	64_N	2.259	1.00
44_Q	48_L	2.254	1.00
388_T	393_A	2.253	1.00
275_L	283_V	2.235	1.00
333_T	341_S	2.231	1.00
134_M	138_C	2.196	1.00
117_I	382_T	2.156	1.00
328_G	349_C	2.151	1.00
135_E	162_N	2.133	1.00
93_V	279_P	2.132	1.00
159_R	384_E	2.122	1.00
129_D	132_K	2.115	1.00
236_E	259_F	2.096	1.00
102_Y	415_S	2.096	1.00
131_A	157_M	2.060	1.00
338_N	369_A	2.031	1.00
104_L	114_I	2.025	1.00
339_L	372_N	1.983	1.00
105_R	268_I	1.959	0.99
233_V	237_L	1.945	0.99
124_I	156_A	1.917	0.99
89_K	282_C	1.895	0.99
189_G	208_K	1.888	0.99
70_K	137_M	1.884	0.99
102_Y	419_D	1.876	0.99
233_V	236_E	1.871	0.99
283_V	287_E	1.870	0.99
27_A	316_E	1.851	0.99
142_W	164_K	1.836	0.99
213_L	216_E	1.822	0.99
44_Q	47_Q	1.815	0.99
158_L	331_L	1.794	0.99
54_R	63_I	1.794	0.99
334_G	341_S	1.791	0.99
124_I	152_T	1.785	0.99
18_V	33_F	1.781	0.99
202_W	260_I	1.754	0.99
128_F	156_A	1.742	0.99
71_L	74_Q	1.737	0.99
316_E	320_T	1.721	0.99
350_V	359_C	1.705	0.99
94_I	423_A	1.701	0.99
384_E	388_T	1.682	0.98
390_K	393_A	1.659	0.98
34_A	66_Y	1.658	0.98
234_R	237_L	1.658	0.98
140_D	164_K	1.626	0.98
384_E	393_A	1.613	0.98
318_M	321_N	1.608	0.98
183_L	217_I	1.583	0.98
123_T	126_V	1.570	0.98
219_R	223_E	1.551	0.97
48_L	51_E	1.542	0.97
393_A	396_Q	1.540	0.97
78_Y	318_M	1.530	0.97
3_K	32_E	1.529	0.97
338_N	362_G	1.527	0.97
216_E	220_R	1.524	0.97
28_L	315_I	1.521	0.97
64_N	71_L	1.514	0.97
114_I	404_T	1.514	0.97
323_P	352_D	1.507	0.97
193_R	205_E	1.496	0.97
45_E	293_R	1.492	0.97
325_T	350_V	1.492	0.97
352_D	355_K	1.491	0.97
93_V	278_Y	1.489	0.97
89_K	93_V	1.486	0.97
77_G	140_D	1.483	0.96
5_T	76_A	1.481	0.96
117_I	378_T	1.480	0.96
40_P	44_Q	1.478	0.96
127_L	157_M	1.474	0.96
10_G	37_D	1.463	0.96
287_E	303_T	1.453	0.96
131_A	134_M	1.453	0.96
237_L	240_K	1.435	0.96
112_V	375_N	1.430	0.96
337_T	362_G	1.421	0.96
386_A	389_R	1.413	0.95
157_M	165_T	1.411	0.95
352_D	356_I	1.387	0.95
54_R	61_V	1.359	0.94
369_A	373_R	1.353	0.94
385_A	394_V	1.349	0.94
185_M	208_K	1.334	0.94
237_L	241_F	1.311	0.93
290_E	293_R	1.310	0.93
5_T	34_A	1.297	0.93
104_L	409_S	1.292	0.93
102_Y	416_M	1.292	0.93
79_V	134_M	1.281	0.92
326_F	351_A	1.278	0.92
124_I	386_A	1.277	0.92
306_R	312_S	1.277	0.92
66_Y	72_A	1.270	0.92
266_E	270_E	1.269	0.92
416_M	420_L	1.260	0.92
278_Y	282_C	1.249	0.91
31_F	62_A	1.247	0.91
98_I	423_A	1.241	0.91
354_K	357_T	1.239	0.91
39_D	87_G	1.231	0.91
79_V	141_A	1.230	0.91
5_T	73_L	1.229	0.91
74_Q	137_M	1.228	0.91
128_F	387_V	1.226	0.90
191_E	207_K	1.211	0.90
398_A	420_L	1.206	0.90
125_P	386_A	1.203	0.90
337_T	341_S	1.197	0.89
93_V	97_E	1.197	0.89
81_N	127_L	1.190	0.89
307_S	311_G	1.189	0.89
94_I	424_H	1.175	0.89
422_A	425_G	1.169	0.88
27_A	322_E	1.163	0.88
279_P	282_C	1.154	0.88
51_E	55_D	1.153	0.88
44_Q	65_S	1.152	0.88
75_N	140_D	1.152	0.88
4_I	28_L	1.146	0.87
299_N	302_L	1.135	0.87
195_A	204_L	1.127	0.86
131_A	163_I	1.121	0.86
366_E	377_N	1.120	0.86
41_K	293_R	1.111	0.86
236_E	240_K	1.108	0.85
36_Y	72_A	1.107	0.85
338_N	373_R	1.103	0.85
336_I	345_V	1.102	0.85
84_Q	92_T	1.100	0.85
335_L	347_V	1.095	0.85
195_A	364_L	1.094	0.85
337_T	360_F	1.092	0.85
99_P	102_Y	1.091	0.84
391_K	417_C	1.088	0.84
200_M	375_N	1.088	0.84
321_N	353_R	1.085	0.84
267_L	271_L	1.077	0.84
215_P	242_G	1.076	0.84
378_T	398_A	1.075	0.84
263_N	406_A	1.073	0.83
325_T	359_C	1.072	0.83
127_L	153_L	1.062	0.83
216_E	219_R	1.059	0.83
269_S	273_I	1.059	0.83
73_L	137_M	1.053	0.82
99_P	420_L	1.050	0.82
2_K	31_F	1.048	0.82
330_V	349_C	1.045	0.82
95_D	122_R	1.041	0.82
135_E	163_I	1.040	0.82
294_D	299_N	1.038	0.81
50_L	63_I	1.035	0.81
176_T	192_E	1.031	0.81
7_I	143_F	1.028	0.81
350_V	357_T	1.025	0.81
233_V	240_K	1.022	0.80
104_L	405_S	1.019	0.80
284_K	288_N	1.019	0.80
263_N	409_S	1.019	0.80
133_D	137_M	1.018	0.80
405_S	409_S	1.014	0.80
394_V	421_F	1.008	0.79
222_K	239_D	1.006	0.79
367_Q	396_Q	1.005	0.79
160_Y	387_V	1.004	0.79
307_S	310_Y	1.000	0.79
391_K	411_K	0.999	0.79
116_G	122_R	0.999	0.79
225_Q	228_K	0.997	0.79
118_F	421_F	0.994	0.78
235_F	239_D	0.991	0.78
43_L	65_S	0.988	0.78
92_T	96_F	0.988	0.78
151_A	379_Q	0.980	0.77
7_I	130_I	0.978	0.77
194_I	203_L	0.976	0.77
205_E	214_Y	0.972	0.77
325_T	348_T	0.971	0.77
89_K	94_I	0.967	0.77
93_V	282_C	0.966	0.76
111_T	116_G	0.966	0.76
83_I	150_M	0.964	0.76
40_P	67_D	0.957	0.76
212_D	215_P	0.952	0.75
233_V	241_F	0.947	0.75
218_K	238_M	0.947	0.75
200_M	371_L	0.940	0.74
307_S	312_S	0.937	0.74
83_I	130_I	0.935	0.74
155_G	380_L	0.934	0.74
153_L	156_A	0.928	0.74
291_K	294_D	0.926	0.73
169_C	199_H	0.926	0.73
234_R	238_M	0.925	0.73
174_V	178_D	0.924	0.73
106_Q	115_G	0.920	0.73
391_K	421_F	0.919	0.73
132_K	136_E	0.915	0.72
232_M	237_L	0.910	0.72
338_N	345_V	0.904	0.72
194_I	201_A	0.904	0.72
120_S	344_V	0.901	0.71
126_V	129_D	0.899	0.71
176_T	203_L	0.898	0.71
398_A	410_M	0.895	0.71
5_T	36_Y	0.895	0.71
171_S	254_E	0.886	0.70
227_T	230_H	0.882	0.70
117_I	398_A	0.877	0.69
97_E	279_P	0.877	0.69
343_A	376_I	0.872	0.69
236_E	411_K	0.871	0.69
271_L	274_P	0.868	0.68
101_R	271_L	0.865	0.68
375_N	401_D	0.862	0.68
191_E	325_T	0.860	0.68
421_F	425_G	0.860	0.68
336_I	362_G	0.859	0.68
330_V	351_A	0.857	0.67
112_V	401_D	0.856	0.67
76_A	138_C	0.853	0.67
313_R	324_F	0.852	0.67
129_D	133_D	0.852	0.67
274_P	277_E	0.852	0.67
155_G	159_R	0.852	0.67
166_I	318_M	0.846	0.66
233_V	238_M	0.845	0.66
398_A	416_M	0.838	0.66
186_E	208_K	0.832	0.65
142_W	318_M	0.832	0.65
9_A	410_M	0.831	0.65
349_C	358_P	0.829	0.65
118_F	424_H	0.827	0.65
343_A	380_L	0.827	0.65
391_K	395_Y	0.826	0.65
236_E	239_D	0.825	0.64
389_R	429_P	0.821	0.64
132_K	160_Y	0.819	0.64
12_T	289_W	0.815	0.63
99_P	416_M	0.814	0.63
150_M	172_V	0.811	0.63
120_S	124_I	0.809	0.63
159_R	380_L	0.809	0.63
220_R	224_K	0.802	0.62
78_Y	315_I	0.799	0.62
394_V	429_P	0.794	0.61
415_S	418_D	0.793	0.61
13_I	82_A	0.792	0.61
370_A	377_N	0.791	0.61
56_R	298_N	0.790	0.61
84_Q	96_F	0.789	0.61
2_K	319_E	0.788	0.61
73_L	79_V	0.784	0.60
176_T	187_H	0.782	0.60
144_L	315_I	0.771	0.59
338_N	363_E	0.769	0.59
40_P	219_R	0.769	0.59
420_L	423_A	0.767	0.59
54_R	59_P	0.764	0.58
99_P	115_G	0.763	0.58
327_G	348_T	0.763	0.58
215_P	219_R	0.762	0.58
351_A	356_I	0.760	0.58
238_M	241_F	0.759	0.58
112_V	259_F	0.756	0.58
290_E	294_D	0.756	0.58
6_F	80_I	0.755	0.58
193_R	361_A	0.753	0.57
316_E	322_E	0.750	0.57
180_F	185_M	0.749	0.57
85_V	123_T	0.749	0.57
232_M	236_E	0.747	0.57
155_G	376_I	0.743	0.56
415_S	419_D	0.740	0.56
51_E	62_A	0.739	0.56
340_P	343_A	0.739	0.56
173_Q	314_I	0.739	0.56
201_A	246_T	0.739	0.56
234_R	240_K	0.738	0.56
306_R	311_G	0.738	0.56
41_K	341_S	0.735	0.56
143_F	157_M	0.735	0.56
158_L	165_T	0.733	0.55
114_I	398_A	0.733	0.55
404_T	410_M	0.730	0.55
177_K	187_H	0.730	0.55
374_T	400_L	0.729	0.55
76_A	79_V	0.728	0.55
399_M	410_M	0.728	0.55
4_I	21_D	0.727	0.55
175_C	201_A	0.727	0.55
348_T	365_P	0.721	0.54
237_L	245_V	0.721	0.54
377_N	380_L	0.719	0.54
308_K	311_G	0.718	0.54
179_L	206_V	0.716	0.54
106_Q	109_A	0.716	0.54
95_D	116_G	0.716	0.54
381_M	396_Q	0.716	0.54
69_R	73_L	0.714	0.53
66_Y	71_L	0.712	0.53
35_L	50_L	0.712	0.53
146_Y	311_G	0.710	0.53
154_T	167_G	0.709	0.53
51_E	71_L	0.706	0.53
46_S	65_S	0.706	0.53
234_R	241_F	0.704	0.52
170_H	307_S	0.700	0.52
50_L	54_R	0.699	0.52
395_Y	410_M	0.699	0.52
69_R	129_D	0.699	0.52
146_Y	151_A	0.698	0.52
112_V	200_M	0.697	0.52
33_F	61_V	0.697	0.52
184_G	239_D	0.696	0.52
191_E	205_E	0.695	0.51
111_T	152_T	0.695	0.51
118_F	420_L	0.695	0.51
118_F	138_C	0.695	0.51
200_M	401_D	0.694	0.51
14_F	82_A	0.691	0.51
395_Y	398_A	0.690	0.51
119_R	259_F	0.688	0.51
48_L	65_S	0.685	0.50
44_Q	357_T	0.685	0.50
111_T	259_F	0.683	0.50
92_T	277_E	0.683	0.50
106_Q	379_Q	0.681	0.50
100_K	268_I	0.680	0.50
143_F	165_T	0.680	0.50
157_M	163_I	0.679	0.50
195_A	361_A	0.678	0.50
416_M	419_D	0.677	0.50
46_S	50_L	0.676	0.49
7_I	73_L	0.675	0.49
117_I	394_V	0.674	0.49
169_C	198_N	0.673	0.49
170_H	309_E	0.673	0.49
202_W	396_Q	0.672	0.49
140_D	298_N	0.671	0.49
120_S	156_A	0.669	0.49
94_I	98_I	0.668	0.49
182_A	217_I	0.668	0.49
99_P	118_F	0.667	0.49
171_S	246_T	0.667	0.49
367_Q	372_N	0.666	0.48
382_T	398_A	0.663	0.48
285_Q	289_W	0.663	0.48
20_G	154_T	0.663	0.48
317_A	326_F	0.661	0.48
286_I	290_E	0.660	0.48
11_S	16_K	0.659	0.48
130_I	143_F	0.659	0.48
194_I	327_G	0.656	0.47
148_N	198_N	0.654	0.47
426_D	429_P	0.653	0.47
246_T	256_H	0.652	0.47
192_E	203_L	0.652	0.47
98_I	419_D	0.651	0.47
96_F	106_Q	0.651	0.47
399_M	407_E	0.650	0.47
291_K	303_T	0.649	0.47
110_D	119_R	0.649	0.47
214_Y	218_K	0.649	0.47
71_L	422_A	0.648	0.47
179_L	217_I	0.648	0.47
13_I	16_K	0.647	0.46
156_A	386_A	0.647	0.46
188_D	211_T	0.646	0.46
41_K	334_G	0.646	0.46
33_F	418_D	0.646	0.46
219_R	239_D	0.645	0.46
204_L	243_Y	0.644	0.46
277_E	281_R	0.643	0.46
304_H	310_Y	0.643	0.46
185_M	189_G	0.643	0.46
73_L	133_D	0.642	0.46
9_A	47_Q	0.641	0.46
53_L	141_A	0.639	0.46
55_D	190_I	0.638	0.46
347_V	361_A	0.638	0.46
160_Y	388_T	0.636	0.45
114_I	416_M	0.635	0.45
268_I	271_L	0.634	0.45
64_N	136_E	0.633	0.45
41_K	44_Q	0.633	0.45
22_C	317_A	0.633	0.45
96_F	110_D	0.633	0.45
208_K	211_T	0.633	0.45
285_Q	379_Q	0.632	0.45
366_E	373_R	0.631	0.45
8_G	11_S	0.631	0.45
144_L	166_I	0.629	0.45
123_T	386_A	0.629	0.45
74_Q	293_R	0.628	0.45
112_V	378_T	0.628	0.45
106_Q	150_M	0.621	0.44
84_Q	119_R	0.620	0.44
417_C	421_F	0.620	0.44
43_L	67_D	0.619	0.44
376_I	379_Q	0.618	0.44
35_L	63_I	0.617	0.43
14_F	17_N	0.610	0.43
4_I	315_I	0.608	0.43
151_A	375_N	0.608	0.43
33_F	211_T	0.608	0.43
207_K	212_D	0.607	0.42
151_A	200_M	0.606	0.42
338_N	364_L	0.606	0.42
13_I	88_Y	0.604	0.42
323_P	353_R	0.604	0.42
386_A	428_L	0.601	0.42
341_S	363_E	0.601	0.42
228_K	231_D	0.600	0.42
269_S	272_Q	0.599	0.42
282_C	286_I	0.598	0.41
176_T	206_V	0.596	0.41
7_I	38_I	0.595	0.41
165_T	344_V	0.595	0.41
112_V	152_T	0.595	0.41
106_Q	110_D	0.594	0.41
294_D	300_K	0.594	0.41
226_K	230_H	0.594	0.41
89_K	426_D	0.593	0.41
84_Q	379_Q	0.591	0.41
79_V	138_C	0.589	0.41
96_F	109_A	0.589	0.41
345_V	348_T	0.588	0.40
171_S	201_A	0.588	0.40
4_I	103_G	0.587	0.40
2_K	77_G	0.587	0.40
33_F	71_L	0.587	0.40
278_Y	281_R	0.586	0.40
372_N	396_Q	0.584	0.40
378_T	382_T	0.583	0.40
333_T	360_F	0.583	0.40
285_Q	288_N	0.581	0.40
47_Q	63_I	0.581	0.40
283_V	286_I	0.581	0.40
54_R	60_S	0.581	0.40
27_A	315_I	0.580	0.40
67_D	290_E	0.580	0.40
148_N	199_H	0.580	0.40
316_E	349_C	0.579	0.40
236_E	241_F	0.576	0.39
100_K	271_L	0.575	0.39
171_S	175_C	0.573	0.39
398_A	404_T	0.572	0.39
51_E	140_D	0.569	0.39
111_T	122_R	0.569	0.39
335_L	342_K	0.569	0.39
102_Y	271_L	0.569	0.39
267_L	270_E	0.569	0.39
347_V	358_P	0.568	0.39
10_G	38_I	0.568	0.39
204_L	363_E	0.568	0.39
381_M	397_A	0.567	0.38
329_N	344_V	0.566	0.38
362_G	369_A	0.565	0.38
44_Q	269_S	0.564	0.38
75_N	298_N	0.564	0.38
342_K	386_A	0.562	0.38
152_T	406_A	0.562	0.38
55_D	186_E	0.562	0.38
100_K	277_E	0.562	0.38
92_T	111_T	0.559	0.38
371_L	381_M	0.559	0.38
204_L	365_P	0.558	0.38
117_I	120_S	0.558	0.38
148_N	169_C	0.558	0.38
261_K	407_E	0.557	0.37
323_P	350_V	0.557	0.37
36_Y	73_L	0.557	0.37
234_R	411_K	0.556	0.37
177_K	181_K	0.556	0.37
25_T	60_S	0.554	0.37
123_T	153_L	0.553	0.37
183_L	208_K	0.552	0.37
113_G	122_R	0.551	0.37
321_N	352_D	0.550	0.37
281_R	424_H	0.550	0.37
304_H	307_S	0.550	0.37
6_F	17_N	0.547	0.36
172_V	327_G	0.546	0.36
132_K	272_Q	0.545	0.36
95_D	113_G	0.545	0.36
21_D	170_H	0.543	0.36
51_E	239_D	0.542	0.36
49_M	297_V	0.542	0.36
408_L	416_M	0.541	0.36
318_M	322_E	0.541	0.36
96_F	277_E	0.540	0.36
142_W	166_I	0.540	0.36
16_K	20_G	0.540	0.36
132_K	161_T	0.540	0.36
17_N	96_F	0.539	0.36
16_K	82_A	0.539	0.36
195_A	365_P	0.539	0.36
44_Q	75_N	0.539	0.36
5_T	64_N	0.538	0.36
147_T	427_W	0.538	0.36
73_L	112_V	0.538	0.36
119_R	123_T	0.538	0.36
290_E	425_G	0.537	0.36
284_K	287_E	0.537	0.36
5_T	74_Q	0.536	0.35
80_I	315_I	0.536	0.35
84_Q	106_Q	0.535	0.35
98_I	416_M	0.535	0.35
73_L	130_I	0.535	0.35
241_F	245_V	0.534	0.35
365_P	368_L	0.534	0.35
210_G	429_P	0.533	0.35
266_E	384_E	0.533	0.35
193_R	204_L	0.533	0.35
25_T	317_A	0.533	0.35
392_E	396_Q	0.532	0.35
21_D	307_S	0.531	0.35
118_F	373_R	0.531	0.35
167_G	402_P	0.531	0.35
163_I	345_V	0.531	0.35
92_T	424_H	0.531	0.35
7_I	69_R	0.529	0.35
182_A	235_F	0.529	0.35
306_R	310_Y	0.529	0.35
81_N	147_T	0.528	0.35
40_P	136_E	0.528	0.35
51_E	64_N	0.527	0.35
96_F	379_Q	0.527	0.35
373_R	377_N	0.526	0.35
339_L	383_I	0.525	0.34
183_L	216_E	0.524	0.34
333_T	358_P	0.524	0.34
53_L	57_Y	0.524	0.34
152_T	321_N	0.523	0.34
14_F	21_D	0.523	0.34
191_E	323_P	0.523	0.34
51_E	183_L	0.522	0.34
3_K	76_A	0.522	0.34
369_A	380_L	0.521	0.34
180_F	190_I	0.520	0.34
7_I	36_Y	0.519	0.34
147_T	270_E	0.519	0.34
143_F	163_I	0.518	0.34
81_N	134_M	0.517	0.34
190_I	208_K	0.517	0.34
157_M	162_N	0.517	0.34
289_W	292_M	0.517	0.34
96_F	111_T	0.517	0.34
180_F	202_W	0.517	0.34
81_N	165_T	0.516	0.34
221_A	239_D	0.516	0.34
381_M	400_L	0.516	0.34
293_R	296_I	0.515	0.33
50_L	82_A	0.514	0.33
13_I	84_Q	0.514	0.33
81_N	143_F	0.512	0.33
158_L	329_N	0.511	0.33
135_E	157_M	0.510	0.33
62_A	101_R	0.510	0.33
184_G	211_T	0.510	0.33
6_F	87_G	0.509	0.33
213_L	218_K	0.507	0.33
316_E	324_F	0.507	0.33
238_M	245_V	0.507	0.33
375_N	379_Q	0.506	0.33
42_R	255_Y	0.506	0.33
138_C	163_I	0.506	0.33
84_Q	259_F	0.505	0.33
340_P	380_L	0.505	0.33
33_F	174_V	0.505	0.33
378_T	401_D	0.505	0.33
71_L	226_K	0.504	0.32
16_K	307_S	0.503	0.32
111_T	119_R	0.502	0.32
113_G	116_G	0.502	0.32
306_R	309_E	0.502	0.32
178_D	231_D	0.502	0.32
103_G	273_I	0.501	0.32
406_A	410_M	0.501	0.32
217_I	244_Y	0.500	0.32
94_I	101_R	0.500	0.32

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1obbA	2	0.9653	100	0.352	Contact Map
1up7A	3	0.9468	100	0.36	Contact Map
1u8xX	1	0.956	100	0.364	Contact Map
1s6yA	1	0.9306	100	0.364	Contact Map
3fefA	3	0.9444	100	0.397	Contact Map
3u95A	2	0.9769	100	0.413	Contact Map
1pzgA	4	0.7222	100	0.716	Contact Map
4rorA	4	0.7222	100	0.721	Contact Map
3p7mA	4	0.6898	100	0.726	Contact Map
2hjrA	4	0.6944	100	0.728	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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