YKOH - BACSU - GREMLIN Contacts

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YKOH - Sensor histidine kinase YkoH

UniProt:	O34638	Sequences: MKLKTKIHLYTSISLLILLILVHTAVYLIFSSALTSKDAARLADETDNIAEALRAAETEGVALQDMLQAYLPANGMVRVVNGDQKAVMTITKEKAYKDFPLSFHSGETADVRKPDGKLFAEAAVPVIWTDGQVVSLQLVERLENTEESLFLLKIILIAASAAVCIASFFAGSLLARRIINPIRRLMITMKDIQRDKEFKTISLEGQSNDELYQMGLTFNEMAMMLKEHYDKQQQFVQDASHELKTPLTIIESYSSLMKRWGAKKPEVLEESIEAIHSEAVHMKKLTNQLLALAKSHQGLEVDLKTIDLIKAARAVMQTLQSVYQRDILLETDKESLLVKADEERIKQLLTILLDNAIKYSEKPIEMSAGTRNGRPFLSVRDEGIGIPEEHIPHLFERFYRADEARNRKTGGTGLGLSIAKQIADEHGIELSVKSKPGQGTAVTMQFSEQNGGGR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	454 (431)
Sequences:	49802 (43201)
Seq/√Len:	2080.9

ECOLI - BARA CPXA CREC CUSS GLRK BAES PHOQ ENVZ TORS YEDV QSEC RSTB ATOS RCSC RCSD NARX ZRAS DCUS NARQ DPIB BASS ARCB EVGS KDPD PHOR YPDA UHPB NTRB
BACSU - YKOH YCLK CSSS YYCG RESE PHOR YVRG YVCQ DCTS KINB CITS YRKQ MALK KIND YCBM YXDK YESM BCES KINE KINA KINC GLNK LIAS LYTS YBDK COMP YWPD YFIJ YHCY
HALSA - Q9HQ15 Q9HQG5 Q9HQE9 Q9HQ16 O51970 Q9HR10 Q9HRE4 Q9HRG1 Q9HNM2 Q9HNA6 BAT Q9HQB9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
380_R	441_A	4.170	1.00
374_R	445_Q	3.941	1.00
381_D	385_G	3.785	1.00
420_K	424_D	3.664	1.00
306_I	340_A	3.512	1.00
431_S	443_T	3.491	1.00
378_S	441_A	3.335	1.00
254_S	275_I	3.032	1.00
367_S	378_S	3.016	1.00
360_S	382_E	2.963	1.00
378_S	443_T	2.920	1.00
376_F	445_Q	2.917	1.00
391_I	434_S	2.885	1.00
371_R	376_F	2.864	1.00
330_E	365_E	2.798	1.00
369_G	376_F	2.781	1.00
376_F	443_T	2.757	1.00
305_T	339_K	2.685	1.00
258_K	276_H	2.676	1.00
387_P	390_H	2.593	1.00
365_E	380_R	2.582	1.00
432_V	442_V	2.570	1.00
433_K	443_T	2.554	1.00
332_D	367_S	2.501	1.00
433_K	441_A	2.472	1.00
258_K	273_E	2.463	1.00
369_G	378_S	2.454	1.00
435_K	438_Q	2.450	1.00
340_A	426_H	2.444	1.00
251_E	280_V	2.431	1.00
348_L	423_A	2.426	1.00
305_T	337_L	2.425	1.00
367_S	380_R	2.389	1.00
419_A	430_L	2.379	1.00
307_D	310_K	2.326	1.00
390_H	393_H	2.286	1.00
423_A	428_I	2.259	1.00
395_F	430_L	2.242	1.00
386_I	394_L	2.234	1.00
391_I	432_V	2.207	1.00
429_E	445_Q	2.188	1.00
314_A	346_K	2.172	1.00
209_D	212_Y	2.135	1.00
265_P	268_L	2.099	1.00
251_E	279_A	2.091	1.00
304_K	342_E	2.089	1.00
319_L	350_T	2.068	1.00
332_D	365_E	2.034	1.00
434_S	440_T	2.013	1.00
303_L	339_K	1.978	1.00
393_H	396_E	1.955	1.00
423_A	444_M	1.946	1.00
388_E	391_I	1.938	1.00
251_E	283_K	1.926	1.00
431_S	445_Q	1.905	1.00
207_S	212_Y	1.868	1.00
222_A	225_L	1.867	1.00
24_T	28_L	1.847	1.00
348_L	419_A	1.828	1.00
283_K	287_N	1.824	1.00
348_L	422_I	1.793	1.00
234_Q	238_D	1.777	1.00
208_N	212_Y	1.776	1.00
340_A	345_I	1.768	1.00
264_K	268_L	1.763	1.00
393_H	399_Y	1.759	1.00
390_H	399_Y	1.737	1.00
354_D	358_K	1.706	1.00
386_I	390_H	1.700	1.00
349_L	377_L	1.658	1.00
226_K	230_D	1.656	1.00
422_I	426_H	1.653	1.00
341_D	344_R	1.641	1.00
255_S	276_H	1.635	1.00
254_S	276_H	1.633	1.00
386_I	440_T	1.631	1.00
424_D	429_E	1.629	1.00
322_V	357_I	1.605	1.00
309_I	313_R	1.604	1.00
365_E	382_E	1.586	1.00
186_M	213_Q	1.580	1.00
191_D	196_K	1.578	1.00
390_H	401_A	1.570	1.00
258_K	269_E	1.546	1.00
351_I	419_A	1.532	1.00
264_K	267_V	1.521	1.00
253_Y	271_S	1.504	1.00
360_S	364_I	1.497	1.00
232_Q	236_V	1.487	1.00
314_A	342_E	1.479	1.00
189_M	192_I	1.459	1.00
81_N	85_K	1.454	1.00
309_I	368_A	1.451	1.00
381_D	439_G	1.448	1.00
318_T	346_K	1.447	1.00
276_H	280_V	1.447	1.00
215_G	219_N	1.443	1.00
377_L	444_M	1.442	1.00
211_L	215_G	1.440	1.00
227_E	231_K	1.432	1.00
257_M	272_I	1.427	1.00
395_F	432_V	1.426	1.00
230_D	234_Q	1.424	1.00
250_I	279_A	1.424	1.00
396_E	399_Y	1.422	1.00
391_I	395_F	1.414	1.00
348_L	444_M	1.412	1.00
423_A	430_L	1.402	1.00
307_D	337_L	1.399	1.00
371_R	445_Q	1.397	1.00
249_I	253_Y	1.391	1.00
434_S	437_G	1.389	1.00
434_S	438_Q	1.388	1.00
320_Q	323_Y	1.379	1.00
196_K	199_K	1.374	1.00
171_G	175_A	1.368	1.00
186_M	190_K	1.367	1.00
344_R	425_E	1.364	1.00
344_R	347_Q	1.363	1.00
387_P	436_P	1.353	1.00
207_S	215_G	1.351	1.00
250_I	275_I	1.337	1.00
307_D	335_S	1.332	1.00
316_M	331_T	1.331	1.00
260_W	268_L	1.328	1.00
226_K	229_Y	1.321	1.00
218_F	221_M	1.314	1.00
251_E	276_H	1.313	1.00
342_E	346_K	1.312	1.00
222_A	226_K	1.297	1.00
360_S	363_P	1.292	1.00
207_S	211_L	1.292	1.00
374_R	429_E	1.286	1.00
421_Q	424_D	1.286	1.00
228_H	231_K	1.285	1.00
242_E	347_Q	1.279	1.00
221_M	225_L	1.275	1.00
301_V	341_D	1.252	1.00
191_D	199_K	1.246	1.00
359_Y	400_R	1.239	1.00
25_A	29_I	1.226	1.00
257_M	268_L	1.220	1.00
183_R	186_M	1.204	1.00
313_R	331_T	1.203	1.00
254_S	258_K	1.200	1.00
235_F	239_A	1.200	1.00
344_R	422_I	1.183	1.00
249_I	278_E	1.179	1.00
402_D	405_R	1.174	1.00
371_R	374_R	1.173	1.00
428_I	446_F	1.173	1.00
311_A	315_V	1.171	1.00
253_Y	274_A	1.170	1.00
31_S	35_T	1.169	1.00
273_E	277_S	1.165	1.00
254_S	279_A	1.159	1.00
211_L	214_M	1.157	1.00
284_K	343_E	1.151	1.00
176_R	180_N	1.149	1.00
249_I	252_S	1.148	1.00
208_N	211_L	1.141	1.00
192_I	222_A	1.136	1.00
142_L	146_E	1.134	1.00
229_Y	232_Q	1.123	1.00
388_E	434_S	1.118	1.00
217_T	220_E	1.115	1.00
315_V	350_T	1.113	1.00
269_E	273_E	1.110	1.00
394_L	432_V	1.110	1.00
395_F	420_K	1.109	1.00
154_I	158_A	1.106	1.00
238_D	397_R	1.104	1.00
39_A	43_A	1.098	1.00
380_R	435_K	1.096	1.00
432_V	440_T	1.093	1.00
252_S	256_L	1.090	1.00
46_T	50_A	1.087	1.00
315_V	346_K	1.085	1.00
265_P	269_E	1.083	1.00
122_A	125_P	1.078	1.00
351_I	354_D	1.078	1.00
200_T	223_M	1.076	1.00
395_F	442_V	1.073	1.00
312_A	368_A	1.071	1.00
287_N	291_A	1.071	1.00
251_E	255_S	1.069	1.00
356_A	364_I	1.058	1.00
189_M	218_F	1.054	1.00
336_L	375_P	1.053	1.00
290_L	293_A	1.045	1.00
219_N	222_A	1.041	1.00
175_A	179_I	1.040	1.00
188_T	201_I	1.027	1.00
189_M	193_Q	1.023	1.00
309_I	335_S	1.023	1.00
150_F	154_I	1.020	1.00
316_M	320_Q	1.019	1.00
212_Y	216_L	1.019	1.00
278_E	281_H	1.018	1.00
386_I	391_I	1.016	1.00
315_V	319_L	1.015	1.00
212_Y	215_G	1.015	1.00
43_A	47_D	1.015	1.00
185_L	189_M	1.012	1.00
397_R	421_Q	1.007	1.00
301_V	344_R	1.001	1.00
386_I	432_V	1.001	1.00
23_H	27_Y	0.998	1.00
189_M	217_T	0.993	1.00
303_L	426_H	0.991	1.00
200_T	219_N	0.991	1.00
352_L	430_L	0.990	1.00
234_Q	397_R	0.989	1.00
27_Y	153_K	0.987	1.00
186_M	189_M	0.987	1.00
190_K	213_Q	0.984	1.00
381_D	440_T	0.983	1.00
80_V	86_A	0.980	1.00
45_E	48_N	0.977	1.00
186_M	217_T	0.975	1.00
63_L	66_M	0.968	1.00
270_E	274_A	0.965	1.00
169_F	173_L	0.964	1.00
306_I	311_A	0.964	1.00
178_I	181_P	0.964	1.00
345_I	426_H	0.962	1.00
310_K	314_A	0.960	1.00
173_L	177_R	0.957	1.00
50_A	54_R	0.952	1.00
244_K	287_N	0.952	1.00
284_K	288_Q	0.951	1.00
319_L	353_L	0.947	1.00
35_T	39_A	0.947	1.00
352_L	442_V	0.945	1.00
346_K	350_T	0.944	1.00
405_R	410_G	0.939	1.00
363_P	382_E	0.936	1.00
311_A	340_A	0.935	1.00
28_L	32_S	0.933	1.00
134_V	138_L	0.930	1.00
336_L	370_T	0.926	1.00
352_L	419_A	0.925	1.00
6_K	209_D	0.925	1.00
172_S	176_R	0.924	1.00
350_T	354_D	0.920	1.00
349_L	353_L	0.917	1.00
273_E	276_H	0.916	1.00
261_G	268_L	0.907	1.00
214_M	218_F	0.906	1.00
254_S	272_I	0.906	1.00
28_L	31_S	0.903	1.00
193_Q	220_E	0.903	1.00
288_Q	344_R	0.898	1.00
349_L	379_V	0.897	1.00
313_R	317_Q	0.895	1.00
203_L	216_L	0.893	1.00
46_T	49_I	0.891	1.00
42_L	46_T	0.891	1.00
121_E	124_V	0.891	1.00
37_K	41_R	0.889	1.00
318_T	350_T	0.889	1.00
266_E	269_E	0.887	1.00
280_V	283_K	0.886	1.00
303_L	427_G	0.885	1.00
242_E	351_I	0.877	1.00
64_Q	68_Q	0.877	1.00
168_F	172_S	0.869	1.00
59_E	62_A	0.868	1.00
307_D	336_L	0.867	1.00
352_L	444_M	0.862	1.00
359_Y	384_I	0.861	1.00
192_I	221_M	0.859	1.00
414_L	418_I	0.858	1.00
343_E	346_K	0.857	1.00
220_E	224_M	0.855	1.00
386_I	392_P	0.851	1.00
224_M	227_E	0.849	1.00
203_L	207_S	0.848	1.00
38_D	41_R	0.847	1.00
275_I	279_A	0.843	1.00
308_L	377_L	0.841	1.00
319_L	354_D	0.838	1.00
423_A	446_F	0.838	1.00
135_S	139_V	0.837	1.00
353_L	366_M	0.835	1.00
202_S	219_N	0.834	1.00
324_Q	327_I	0.833	1.00
327_I	360_S	0.833	1.00
41_R	44_D	0.833	1.00
274_A	278_E	0.832	1.00
394_L	442_V	0.829	1.00
229_Y	233_Q	0.829	1.00
279_A	283_K	0.823	1.00
421_Q	425_E	0.821	1.00
215_G	218_F	0.818	1.00
328_L	331_T	0.818	1.00
270_E	273_E	0.817	1.00
315_V	353_L	0.816	1.00
188_T	199_K	0.816	1.00
245_T	249_I	0.815	1.00
119_F	123_A	0.810	1.00
333_K	336_L	0.810	1.00
428_I	444_M	0.809	1.00
385_G	440_T	0.809	1.00
256_L	260_W	0.803	1.00
326_D	362_K	0.802	1.00
150_F	153_K	0.802	1.00
78_R	137_Q	0.801	1.00
277_S	314_A	0.800	1.00
37_K	40_A	0.798	1.00
188_T	191_D	0.798	1.00
38_D	42_L	0.797	1.00
242_E	246_P	0.793	1.00
40_A	43_A	0.793	1.00
177_R	180_N	0.793	1.00
63_L	67_L	0.792	1.00
419_A	423_A	0.791	1.00
268_L	271_S	0.789	1.00
420_K	429_E	0.789	1.00
86_A	89_T	0.787	1.00
291_A	347_Q	0.786	1.00
187_I	191_D	0.786	1.00
41_R	45_E	0.785	1.00
306_I	342_E	0.784	1.00
227_E	230_D	0.784	1.00
374_R	447_S	0.782	1.00
213_Q	216_L	0.778	1.00
244_K	283_K	0.778	1.00
120_A	123_A	0.777	1.00
35_T	38_D	0.775	1.00
327_I	331_T	0.774	1.00
241_H	245_T	0.774	1.00
190_K	217_T	0.771	1.00
183_R	187_I	0.769	1.00
196_K	200_T	0.769	1.00
317_Q	320_Q	0.768	1.00
213_Q	217_T	0.767	1.00
366_M	379_V	0.766	1.00
177_R	181_P	0.761	1.00
125_P	135_S	0.759	1.00
40_A	44_D	0.758	1.00
151_L	155_I	0.758	1.00
314_A	318_T	0.758	1.00
36_S	39_A	0.757	1.00
388_E	392_P	0.754	1.00
189_M	221_M	0.754	1.00
181_P	185_L	0.753	1.00
209_D	213_Q	0.752	1.00
14_S	18_L	0.750	1.00
301_V	425_E	0.748	1.00
347_Q	422_I	0.748	1.00
33_A	37_K	0.740	1.00
312_A	349_L	0.739	1.00
253_Y	275_I	0.739	1.00
312_A	366_M	0.738	1.00
153_K	157_I	0.738	1.00
146_E	150_F	0.737	1.00
313_R	316_M	0.735	1.00
378_S	433_K	0.735	1.00
303_L	340_A	0.734	1.00
391_I	433_K	0.734	1.00
189_M	214_M	0.732	1.00
175_A	178_I	0.732	1.00
239_A	289_L	0.729	1.00
255_S	259_R	0.729	1.00
89_T	92_K	0.727	1.00
418_I	422_I	0.727	1.00
208_N	215_G	0.727	1.00
78_R	86_A	0.727	1.00
51_E	55_A	0.727	1.00
400_R	411_G	0.722	1.00
42_L	45_E	0.721	1.00
250_I	254_S	0.721	1.00
253_Y	278_E	0.721	1.00
116_G	119_F	0.717	1.00
316_M	329_L	0.715	1.00
292_L	417_S	0.713	1.00
190_K	194_R	0.712	1.00
282_M	286_T	0.711	1.00
60_G	64_Q	0.711	1.00
123_A	135_S	0.709	1.00
381_D	384_I	0.709	1.00
201_I	219_N	0.705	1.00
214_M	217_T	0.704	1.00
335_S	338_V	0.704	1.00
281_H	346_K	0.704	1.00
352_L	423_A	0.702	1.00
149_L	153_K	0.702	1.00
32_S	36_S	0.701	1.00
302_D	341_D	0.700	1.00
258_K	272_I	0.699	1.00
274_A	277_S	0.696	1.00
20_I	24_T	0.695	1.00
308_L	338_V	0.694	1.00
290_L	294_K	0.694	1.00
32_S	35_T	0.693	1.00
322_V	364_I	0.693	1.00
276_H	279_A	0.692	1.00
261_G	265_P	0.692	1.00
386_I	434_S	0.692	1.00
66_M	70_Y	0.691	1.00
145_T	149_L	0.690	1.00
34_L	37_K	0.690	1.00
348_L	426_H	0.689	1.00
223_M	227_E	0.689	1.00
344_R	426_H	0.688	1.00
47_D	50_A	0.688	1.00
323_Y	326_D	0.687	1.00
217_T	221_M	0.679	1.00
157_I	161_A	0.679	1.00
154_I	157_I	0.679	1.00
255_S	258_K	0.677	1.00
44_D	47_D	0.677	1.00
309_I	336_L	0.676	1.00
92_K	95_A	0.676	1.00
368_A	375_P	0.673	1.00
236_V	239_A	0.672	1.00
306_I	339_K	0.672	1.00
241_H	351_I	0.671	1.00
308_L	375_P	0.671	1.00
388_E	435_K	0.668	1.00
27_Y	31_S	0.668	1.00
199_K	203_L	0.664	1.00
310_K	342_E	0.664	1.00
80_V	137_Q	0.661	1.00
10_Y	14_S	0.661	1.00
182_I	185_L	0.661	1.00
68_Q	71_L	0.660	1.00
390_H	403_E	0.660	1.00
216_L	219_N	0.660	1.00
395_F	398_F	0.658	1.00
364_I	379_V	0.658	1.00
317_Q	321_S	0.658	1.00
216_L	220_E	0.658	1.00
376_F	431_S	0.657	1.00
195_D	199_K	0.657	1.00
288_Q	347_Q	0.657	1.00
334_E	370_T	0.656	1.00
386_I	442_V	0.656	1.00
51_E	54_R	0.656	1.00
260_W	271_S	0.654	1.00
39_A	42_L	0.654	1.00
207_S	214_M	0.654	1.00
201_I	215_G	0.654	1.00
214_M	219_N	0.653	1.00
199_K	202_S	0.652	1.00
119_F	122_A	0.652	1.00
13_I	16_L	0.652	1.00
67_L	70_Y	0.651	1.00
21_L	25_A	0.650	1.00
401_A	405_R	0.650	1.00
233_Q	296_H	0.650	1.00
24_T	27_Y	0.650	1.00
370_T	375_P	0.646	1.00
117_K	121_E	0.645	1.00
49_I	52_A	0.643	1.00
198_F	226_K	0.643	1.00
61_V	64_Q	0.642	1.00
39_A	120_A	0.642	1.00
291_A	344_R	0.642	1.00
347_Q	350_T	0.640	1.00
29_I	32_S	0.640	1.00
47_D	51_E	0.640	1.00
327_I	357_I	0.639	1.00
207_S	210_E	0.639	1.00
272_I	276_H	0.638	1.00
322_V	329_L	0.636	1.00
91_T	94_K	0.636	1.00
167_S	171_G	0.634	1.00
197_E	200_T	0.634	1.00
321_S	324_Q	0.633	1.00
271_S	275_I	0.633	1.00
184_R	187_I	0.631	1.00
419_A	422_I	0.630	1.00
185_L	215_G	0.630	1.00
243_L	246_P	0.630	1.00
387_P	401_A	0.629	1.00
368_A	377_L	0.629	1.00
356_A	379_V	0.629	1.00
243_L	282_M	0.626	1.00
394_L	417_S	0.623	1.00
358_K	411_G	0.623	1.00
235_F	242_E	0.623	1.00
271_S	274_A	0.621	1.00
289_L	293_A	0.621	1.00
52_A	55_A	0.621	1.00
391_I	442_V	0.620	1.00
400_R	410_G	0.617	1.00
283_K	286_T	0.617	1.00
299_L	344_R	0.616	1.00
36_S	40_A	0.616	1.00
219_N	223_M	0.616	1.00
325_R	360_S	0.615	1.00
184_R	188_T	0.615	1.00
266_E	270_E	0.613	1.00
145_T	148_S	0.611	1.00
253_Y	257_M	0.611	1.00
430_L	442_V	0.611	1.00
247_L	286_T	0.611	1.00
396_E	420_K	0.611	1.00
33_A	36_S	0.610	1.00
11_T	171_G	0.607	1.00
428_I	447_S	0.606	1.00
108_T	112_R	0.606	1.00
344_R	348_L	0.605	1.00
29_I	33_A	0.604	1.00
310_K	313_R	0.604	1.00
417_S	421_Q	0.604	1.00
63_L	70_Y	0.602	1.00
353_L	364_I	0.601	1.00
325_R	357_I	0.601	1.00
267_V	271_S	0.600	1.00
380_R	437_G	0.600	1.00
309_I	334_E	0.599	1.00
248_T	252_S	0.598	1.00
65_D	68_Q	0.597	1.00
114_P	117_K	0.596	1.00
81_N	87_V	0.594	1.00
118_L	121_E	0.594	1.00
121_E	139_V	0.592	1.00
311_A	345_I	0.592	1.00
75_G	78_R	0.592	1.00
260_W	267_V	0.590	1.00
322_V	327_I	0.590	1.00
256_L	271_S	0.590	1.00
60_G	63_L	0.589	1.00
62_A	65_D	0.589	1.00
245_T	252_S	0.587	1.00
25_A	28_L	0.586	1.00
224_M	228_H	0.586	1.00
315_V	318_T	0.584	1.00
248_T	251_E	0.584	1.00
58_T	61_V	0.583	1.00
280_V	284_K	0.582	1.00
103_F	111_V	0.581	1.00
256_L	261_G	0.581	1.00
161_A	165_I	0.581	1.00
319_L	357_I	0.580	1.00
267_V	270_E	0.579	1.00
130_D	134_V	0.579	1.00
309_I	333_K	0.576	1.00
76_M	89_T	0.576	1.00
193_Q	196_K	0.575	1.00
332_D	369_G	0.575	1.00
184_R	202_S	0.575	1.00
296_H	397_R	0.573	1.00
53_L	57_E	0.572	1.00
185_L	188_T	0.569	1.00
228_H	232_Q	0.568	1.00
195_D	200_T	0.567	1.00
258_K	261_G	0.566	1.00
322_V	326_D	0.566	1.00
151_L	154_I	0.566	1.00
243_L	247_L	0.565	1.00
293_A	296_H	0.564	1.00
208_N	214_M	0.564	1.00
278_E	318_T	0.564	1.00
252_S	279_A	0.564	1.00
392_P	396_E	0.562	1.00
249_I	274_A	0.560	1.00
338_V	341_D	0.560	1.00
143_E	146_E	0.560	1.00
182_I	186_M	0.559	1.00
180_N	184_R	0.557	1.00
195_D	198_F	0.557	1.00
131_G	134_V	0.556	1.00
158_A	162_A	0.556	1.00
191_D	194_R	0.554	1.00
230_D	233_Q	0.554	1.00
242_E	418_I	0.553	1.00
292_L	421_Q	0.552	1.00
221_M	224_M	0.551	1.00
356_A	360_S	0.550	1.00
44_D	48_N	0.549	1.00
311_A	346_K	0.549	1.00
130_D	133_V	0.549	1.00
30_F	33_A	0.548	1.00
257_M	271_S	0.548	1.00
187_I	190_K	0.548	1.00
52_A	56_A	0.547	1.00
115_D	119_F	0.547	1.00
193_Q	224_M	0.546	1.00
277_S	280_V	0.546	1.00
316_M	366_M	0.545	1.00
238_D	242_E	0.545	1.00
314_A	317_Q	0.545	1.00
123_A	126_V	0.545	1.00
431_S	444_M	0.545	1.00
46_T	138_L	0.545	1.00
200_T	222_A	0.544	1.00
113_K	117_K	0.543	1.00
142_L	145_T	0.541	1.00
253_Y	256_L	0.540	1.00
391_I	440_T	0.539	1.00
53_L	56_A	0.539	1.00
365_E	368_A	0.539	1.00
203_L	215_G	0.538	1.00
293_A	297_Q	0.537	1.00
68_Q	72_P	0.537	1.00
370_T	374_R	0.536	1.00
261_G	264_K	0.536	1.00
45_E	49_I	0.535	1.00
242_E	285_L	0.534	1.00
90_I	93_E	0.534	1.00
49_I	53_L	0.533	1.00
241_H	246_P	0.533	1.00
361_E	382_E	0.533	1.00
218_F	222_A	0.532	1.00
345_I	446_F	0.532	1.00
13_I	20_I	0.532	1.00
304_K	343_E	0.531	1.00
91_T	95_A	0.531	1.00
322_V	325_R	0.530	1.00
144_N	147_E	0.530	1.00
31_S	34_L	0.530	1.00
81_N	84_Q	0.530	1.00
253_Y	279_A	0.528	1.00
353_L	357_I	0.528	1.00
380_R	438_Q	0.528	1.00
325_R	362_K	0.528	1.00
120_A	124_V	0.528	1.00
16_L	20_I	0.525	1.00
394_L	399_Y	0.524	1.00
155_I	158_A	0.523	1.00
236_V	240_S	0.521	1.00
193_Q	197_E	0.520	1.00
26_V	30_F	0.519	1.00
123_A	137_Q	0.518	1.00
301_V	426_H	0.518	1.00
387_P	391_I	0.516	1.00
248_T	253_Y	0.515	1.00
181_P	207_S	0.514	1.00
169_F	172_S	0.510	1.00
312_A	315_V	0.510	1.00
309_I	331_T	0.508	1.00
311_A	314_A	0.507	1.00
334_E	337_L	0.507	1.00
288_Q	343_E	0.507	1.00
260_W	265_P	0.506	1.00
282_M	290_L	0.506	1.00
62_A	66_M	0.505	1.00
292_L	397_R	0.505	1.00
147_E	151_L	0.504	1.00
404_A	410_G	0.503	1.00
74_N	77_V	0.502	1.00
240_S	245_T	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i5sA	2	0.5903	100	0.354	Contact Map
4bixA	2	0.4978	100	0.371	Contact Map
4ctiA	2	0.5044	100	0.396	Contact Map
4q20A	2	0.4956	100	0.479	Contact Map
4gczA	2	0.7841	100	0.483	Contact Map
4mpcA	2	0.652	100	0.484	Contact Map
2e0aA	2	0.6762	100	0.49	Contact Map
2q8gA	2	0.6608	100	0.491	Contact Map
3jz3A	2	0.348	100	0.494	Contact Map
2c2aA	2	0.5044	100	0.495	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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