DPO3A - BACSU - GREMLIN Contacts

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DPO3A - DNA polymerase III subunit alpha

UniProt:	O34623	Sequences: MSFVHLQVHSGYSLLNSAAAVEELVSEADRLGYASLALTDDHVMYGAIQFYKACKARGINPIIGLTASVFTDDSELEAYPLVLLAKSNTGYQNLLKISSVLQSKSKGGLKPKWLHSYREGIIAITPGEKGYIETLLEGGLFEQAAQASLEFQSIFGKGAFYFSYQPFKGNQVLSEQILKLSEETGIPVTATGDVHYIRKEDKAAYRCLKAIKAGEKLTDAPAEDLPDLDLKPLEEMQNIYREHPEALQASVEIAEQCRVDVSLGQTRLPSFPTPDGTSADDYLTDICMEGLRSRFGKPDERYLRRLQYELDVIKRMKFSDYFLIVWDFMKHAHEKGIVTGPGRGSAAGSLVAYVLYITDVDPIKHHLLFERFLNPERVSMPDIDIDFPDTRRDEVIQYVQQKYGAMHVAQIITFGTLAAKAALRDVGRVFGVSPKEADQLAKLIPSRPGMTLDEARQQSPQLDKRLRESSLLQQVYSIARKIEGLPRHASTHAAGVVLSEEPLTDVVPLQEGHEGIYLTQYAMDHLEDLGLLKMDFLGLRNLTLIESITSMIEKEENIKIDLSSISYSDDKTFSLLSKGDTTGIFQLESAGMRSVLKRLKPSGLEDIVAVNALYRPGPMENIPLFIDRKHGRAPVHYPHEDLRSILEDTYGVIVYQEQIMMIASRMAGFSLGEADLLRRAVSKKKKEILDRERSHFVEGCLKKEYSVDTANEVYDLIVKFANYGFNRSHAVAYSMIGCQLAYLKAHYPLYFMCGLLTSVIGNEDKISQYLYEAKGSGIRILPPSVNKSSFPFTVENGSVRYSLRAIKSVGVSAVKDIYKARKEKPFEDLFDFCFRVPSKSVNRKMLEALIFSGAMDEFGQNRATLLASIDVALEHAELFAADDDQMGLFLDESFSIKPKYVETEELPLVDLLAFEKETLGIYFSNHPLSAFRKQLTAQGAVSILQAQRAVKRQLSLGVLLSKIKTIRTKTGQNMAFLTLSDETGEMEAVVFPEQFRQLSPVLREGALLFTAGKCEVRQDKIQFIMSRAELLEDMDAEKAPSVYIKIESSQHSQEILAKIKRILLEHKGETGVYLYYERQKQTIKLPESFHINADHQVLYRLKELLGQKNVVLKQW	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	1115 (1022)
Sequences:	4736 (2842)
Seq/√Len:	88.9

ECOLI - DPO3A
BACSU - DPO3A YORL

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
643_R	647_E	6.052	1.00
391_R	394_E	5.792	1.00
10_S	38_L	5.300	1.00
553_E	559_K	5.250	1.00
145_A	183_E	4.840	1.00
300_E	304_R	3.934	1.00
427_G	437_A	3.896	1.00
784_S	857_E	3.823	1.00
89_T	119_E	3.822	1.00
988_A	1025_M	3.807	1.00
86_K	256_Q	3.763	1.00
640_E	643_R	3.689	1.00
27_E	30_R	3.685	1.00
627_D	632_R	3.565	1.00
285_D	289_E	3.515	1.00
277_T	285_D	3.446	1.00
673_E	695_H	3.435	1.00
576_L	587_L	3.310	1.00
27_E	31_L	3.167	1.00
330_K	334_E	3.121	1.00
574_S	577_S	3.114	1.00
624_L	633_A	3.055	1.00
707_V	711_N	3.030	1.00
561_D	564_S	3.005	1.00
293_S	356_Y	2.938	1.00
698_E	702_K	2.902	1.00
327_D	398_Y	2.894	1.00
288_M	303_L	2.862	1.00
820_A	826_F	2.855	1.00
694_S	698_E	2.852	1.00
627_D	633_A	2.770	1.00
346_A	383_I	2.734	1.00
249_A	252_E	2.720	1.00
277_T	281_D	2.719	1.00
295_F	302_Y	2.699	1.00
686_K	690_D	2.697	1.00
28_A	36_L	2.677	1.00
140_L	143_Q	2.675	1.00
960_L	1008_L	2.650	1.00
955_S	1011_A	2.644	1.00
313_I	351_V	2.628	1.00
111_P	150_E	2.621	1.00
284_T	307_Q	2.609	1.00
86_K	159_A	2.584	1.00
453_D	480_R	2.556	1.00
669_F	692_E	2.456	1.00
52_K	528_D	2.452	1.00
545_I	743_L	2.448	1.00
189_T	253_I	2.435	1.00
942_S	945_Q	2.415	1.00
701_L	707_V	2.388	1.00
1011_A	1027_R	2.386	1.00
546_E	550_S	2.359	1.00
284_T	288_M	2.352	1.00
693_R	711_N	2.347	1.00
315_R	375_P	2.339	1.00
25_V	54_C	2.301	1.00
280_D	314_K	2.300	1.00
570_D	574_S	2.297	1.00
278_S	281_D	2.285	1.00
201_D	481_K	2.269	1.00
572_T	746_H	2.254	1.00
577_S	602_S	2.254	1.00
376_E	672_G	2.224	1.00
83_L	123_A	2.222	1.00
571_K	574_S	2.215	1.00
303_L	307_Q	2.196	1.00
598_R	623_P	2.190	1.00
644_S	665_R	2.189	1.00
787_K	795_E	2.183	1.00
943_I	983_T	2.181	1.00
217_L	429_V	2.177	1.00
132_I	160_F	2.167	1.00
779_R	798_S	2.163	1.00
574_S	578_K	2.158	1.00
832_F	855_M	2.148	1.00
571_K	746_H	2.124	1.00
284_T	314_K	2.118	1.00
466_L	477_S	2.101	1.00
115_H	150_E	2.099	1.00
576_L	581_T	2.092	1.00
580_D	776_S	2.063	1.00
645_I	665_R	2.054	1.00
501_E	505_D	2.039	1.00
715_D	718_V	2.035	1.00
795_E	800_R	2.035	1.00
545_I	562_L	2.034	1.00
67_A	83_L	2.014	1.00
280_D	319_S	2.014	1.00
27_E	198_R	2.010	1.00
781_L	800_R	1.999	1.00
422_A	482_I	1.992	1.00
668_G	703_K	1.982	1.00
311_D	315_R	1.977	1.00
337_I	394_E	1.958	1.00
307_Q	311_D	1.951	1.00
60_N	258_R	1.947	1.00
11_G	20_A	1.942	1.00
26_S	57_R	1.938	1.00
811_V	815_K	1.929	1.00
143_Q	146_Q	1.921	1.00
359_D	563_S	1.921	1.00
203_A	474_Q	1.918	1.00
693_R	715_D	1.916	1.00
199_K	227_D	1.915	1.00
331_H	395_V	1.912	1.00
237_Q	247_L	1.898	1.00
866_L	906_L	1.892	1.00
283_L	310_L	1.891	1.00
87_S	120_G	1.890	1.00
237_Q	248_Q	1.888	1.00
412_I	489_A	1.885	1.00
397_Q	401_Q	1.876	1.00
637_Y	643_R	1.875	1.00
399_V	536_F	1.873	1.00
820_A	823_E	1.873	1.00
907_P	910_D	1.872	1.00
587_L	607_I	1.871	1.00
124_I	189_T	1.869	1.00
288_M	307_Q	1.864	1.00
861_N	905_E	1.860	1.00
641_D	705_Y	1.859	1.00
45_Y	510_Q	1.854	1.00
152_Q	157_K	1.854	1.00
820_A	835_R	1.849	1.00
664_S	671_L	1.843	1.00
815_K	819_K	1.836	1.00
148_S	186_I	1.834	1.00
65_L	98_S	1.827	1.00
619_M	622_I	1.824	1.00
94_L	121_I	1.817	1.00
556_E	747_Y	1.817	1.00
262_S	265_Q	1.813	1.00
88_N	92_Q	1.812	1.00
574_S	602_S	1.808	1.00
968_T	974_M	1.806	1.00
150_E	154_I	1.800	1.00
711_N	715_D	1.789	1.00
594_S	598_R	1.784	1.00
287_C	306_L	1.781	1.00
697_V	701_L	1.775	1.00
693_R	718_V	1.764	1.00
125_T	160_F	1.757	1.00
608_V	731_V	1.747	1.00
37_A	84_L	1.744	1.00
666_M	713_V	1.742	1.00
274_P	282_Y	1.741	1.00
22_E	53_A	1.734	1.00
819_K	823_E	1.728	1.00
331_H	335_K	1.727	1.00
299_D	303_L	1.726	1.00
152_Q	186_I	1.726	1.00
925_N	929_S	1.716	1.00
464_K	468_E	1.710	1.00
577_S	600_K	1.709	1.00
178_L	188_V	1.705	1.00
366_H	661_M	1.704	1.00
289_E	293_S	1.691	1.00
450_M	454_E	1.686	1.00
772_E	776_S	1.684	1.00
227_D	231_K	1.684	1.00
179_K	183_E	1.683	1.00
642_L	662_I	1.682	1.00
337_I	391_R	1.682	1.00
53_A	57_R	1.680	1.00
19_A	197_I	1.677	1.00
424_R	438_D	1.676	1.00
36_L	230_L	1.672	1.00
4_V	251_V	1.666	1.00
828_D	897_K	1.664	1.00
1010_T	1025_M	1.661	1.00
326_W	330_K	1.659	1.00
7_Q	66_T	1.659	1.00
831_D	835_R	1.657	1.00
88_N	259_V	1.656	1.00
905_E	911_L	1.655	1.00
215_E	219_D	1.654	1.00
977_L	990_V	1.651	1.00
863_A	867_A	1.649	1.00
162_F	181_S	1.642	1.00
218_T	431_G	1.642	1.00
295_F	350_L	1.641	1.00
587_L	611_N	1.633	1.00
11_G	485_L	1.631	1.00
85_A	259_V	1.627	1.00
653_I	662_I	1.626	1.00
1013_K	1026_S	1.616	1.00
207_C	478_I	1.606	1.00
100_V	116_S	1.603	1.00
28_A	230_L	1.603	1.00
543_T	547_S	1.601	1.00
251_V	255_E	1.599	1.00
463_D	467_R	1.596	1.00
163_S	191_T	1.592	1.00
641_D	703_K	1.591	1.00
663_A	677_L	1.581	1.00
39_T	84_L	1.580	1.00
145_A	149_L	1.578	1.00
148_S	184_T	1.573	1.00
294_R	359_D	1.559	1.00
279_A	320_D	1.559	1.00
1012_G	1023_F	1.555	1.00
438_D	442_K	1.545	1.00
423_L	444_I	1.543	1.00
697_V	711_N	1.539	1.00
572_T	745_A	1.537	1.00
540_R	758_S	1.533	1.00
424_R	441_A	1.528	1.00
290_G	354_V	1.527	1.00
850_I	869_I	1.527	1.00
988_A	1010_T	1.524	1.00
115_H	154_I	1.520	1.00
316_M	378_V	1.516	1.00
194_V	230_L	1.516	1.00
314_K	319_S	1.516	1.00
943_I	986_M	1.514	1.00
29_D	57_R	1.510	1.00
611_N	734_S	1.506	1.00
850_I	865_L	1.504	1.00
53_A	56_A	1.502	1.00
192_G	231_K	1.501	1.00
299_D	302_Y	1.501	1.00
161_Y	252_E	1.500	1.00
595_V	610_V	1.496	1.00
327_D	402_K	1.495	1.00
188_V	246_A	1.494	1.00
612_A	730_A	1.494	1.00
466_L	476_Y	1.487	1.00
686_K	722_N	1.483	1.00
556_E	750_Y	1.480	1.00
548_I	754_G	1.476	1.00
628_R	633_A	1.476	1.00
100_V	104_K	1.465	0.99
2_S	34_A	1.459	0.99
233_L	237_Q	1.456	0.99
692_E	695_H	1.450	0.99
286_I	289_E	1.438	0.99
187_P	252_E	1.438	0.99
676_L	679_R	1.436	0.99
752_M	776_S	1.436	0.99
149_L	184_T	1.435	0.99
31_L	232_P	1.433	0.99
390_T	547_S	1.431	0.99
555_E	750_Y	1.427	0.99
820_A	824_K	1.426	0.99
231_K	239_I	1.425	0.99
752_M	773_A	1.424	0.99
968_T	992_P	1.423	0.99
935_L	957_G	1.421	0.99
300_E	303_L	1.416	0.99
709_T	712_E	1.410	0.99
20_A	23_E	1.408	0.99
604_L	735_M	1.401	0.99
49_Q	525_H	1.401	0.99
41_D	80_P	1.395	0.99
562_L	565_I	1.394	0.99
795_E	798_S	1.393	0.99
688_I	692_E	1.391	0.99
604_L	608_V	1.390	0.99
637_Y	647_E	1.389	0.99
291_L	354_V	1.385	0.99
270_S	500_E	1.385	0.99
553_E	557_N	1.384	0.99
166_P	171_Q	1.380	0.99
580_D	775_G	1.379	0.99
34_A	251_V	1.379	0.99
124_I	163_S	1.374	0.99
599_L	626_I	1.369	0.99
302_Y	363_I	1.364	0.99
44_M	91_Y	1.363	0.99
575_L	745_A	1.362	0.99
178_L	243_H	1.359	0.99
131_Y	147_A	1.356	0.99
288_M	291_L	1.355	0.99
849_L	854_A	1.353	0.99
602_S	629_K	1.353	0.99
82_V	126_P	1.346	0.99
286_I	326_W	1.345	0.99
115_H	153_S	1.338	0.99
756_L	766_I	1.338	0.99
466_L	473_Q	1.336	0.99
583_G	755_L	1.336	0.99
620_E	623_P	1.330	0.99
524_D	685_K	1.329	0.99
329_M	385_I	1.324	0.99
648_D	727_R	1.321	0.99
453_D	457_Q	1.317	0.99
80_P	127_G	1.315	0.99
436_E	471_L	1.314	0.99
781_L	798_S	1.312	0.99
67_A	109_L	1.312	0.99
207_C	426_V	1.311	0.99
96_K	505_D	1.306	0.99
366_H	648_D	1.300	0.99
241_R	244_P	1.298	0.99
571_K	745_A	1.298	0.99
567_Y	735_M	1.298	0.99
99_S	509_L	1.292	0.99
566_S	738_C	1.288	0.99
960_L	977_L	1.287	0.99
582_T	593_R	1.285	0.99
962_K	978_T	1.280	0.99
302_Y	350_L	1.278	0.99
806_I	852_S	1.278	0.99
36_L	54_C	1.273	0.99
35_S	254_A	1.270	0.98
434_P	438_D	1.269	0.98
473_Q	477_S	1.269	0.98
252_E	256_Q	1.268	0.98
50_F	61_P	1.263	0.98
700_C	705_Y	1.261	0.98
581_T	587_L	1.259	0.98
974_M	991_F	1.258	0.98
628_R	631_G	1.255	0.98
833_C	872_A	1.253	0.98
668_G	699_G	1.252	0.98
329_M	339_T	1.251	0.98
22_E	56_A	1.251	0.98
199_K	226_P	1.249	0.98
851_F	914_F	1.247	0.98
277_T	282_Y	1.246	0.98
619_M	730_A	1.245	0.98
181_S	186_I	1.243	0.98
868_S	901_V	1.239	0.98
291_L	306_L	1.238	0.98
145_A	184_T	1.238	0.98
619_M	623_P	1.237	0.98
789_S	822_K	1.236	0.98
166_P	242_E	1.234	0.98
25_V	57_R	1.232	0.98
562_L	739_Q	1.227	0.98
135_L	140_L	1.227	0.98
628_R	635_V	1.226	0.98
411_I	495_G	1.226	0.98
2_S	233_L	1.225	0.98
161_Y	256_Q	1.222	0.98
596_L	610_V	1.219	0.98
24_L	194_V	1.219	0.98
219_D	222_A	1.217	0.98
432_V	475_V	1.215	0.98
548_I	743_L	1.212	0.98
292_R	299_D	1.211	0.98
438_D	441_A	1.210	0.98
136_L	180_L	1.209	0.98
141_F	179_K	1.207	0.98
622_I	730_A	1.205	0.98
306_L	354_V	1.204	0.98
294_R	356_Y	1.202	0.98
306_L	350_L	1.201	0.98
406_M	502_P	1.200	0.98
252_E	255_E	1.200	0.98
958_V	979_L	1.198	0.98
63_I	91_Y	1.198	0.98
953_Q	1026_S	1.193	0.98
217_L	430_F	1.192	0.98
792_F	801_Y	1.191	0.98
425_D	487_R	1.188	0.98
47_A	63_I	1.185	0.98
789_S	793_T	1.184	0.98
216_K	431_G	1.182	0.98
393_D	397_Q	1.181	0.98
706_S	709_T	1.176	0.97
86_K	90_G	1.175	0.97
361_D	364_K	1.174	0.97
591_G	614_Y	1.171	0.97
540_R	759_V	1.169	0.97
125_T	162_F	1.167	0.97
89_T	120_G	1.167	0.97
206_R	217_L	1.166	0.97
182_E	245_E	1.165	0.97
825_P	835_R	1.164	0.97
659_I	681_V	1.161	0.97
44_M	95_L	1.161	0.97
181_S	187_P	1.159	0.97
688_I	691_R	1.159	0.97
817_I	832_F	1.158	0.97
4_V	34_A	1.157	0.97
170_N	174_S	1.157	0.97
863_A	903_T	1.155	0.97
152_Q	185_G	1.154	0.97
141_F	183_E	1.154	0.97
41_D	127_G	1.149	0.97
958_V	988_A	1.148	0.97
522_A	525_H	1.147	0.97
966_I	976_F	1.145	0.97
461_Q	464_K	1.142	0.97
360_V	731_V	1.142	0.97
541_N	751_F	1.142	0.97
25_V	53_A	1.141	0.97
335_K	394_E	1.140	0.97
21_V	53_A	1.138	0.97
956_L	979_L	1.136	0.97
122_I	161_Y	1.136	0.97
213_A	223_E	1.136	0.97
55_K	260_D	1.136	0.97
912_L	924_S	1.134	0.97
16_N	41_D	1.133	0.97
997_Q	1027_R	1.131	0.97
4_V	35_S	1.129	0.97
136_L	176_Q	1.129	0.97
280_D	284_T	1.127	0.97
67_A	98_S	1.127	0.97
206_R	224_D	1.127	0.97
943_I	956_L	1.125	0.97
790_F	815_K	1.125	0.97
87_S	90_G	1.125	0.97
308_Y	311_D	1.123	0.97
460_P	463_D	1.121	0.97
569_D	746_H	1.120	0.97
93_N	120_G	1.119	0.97
151_F	160_F	1.118	0.97
557_N	560_I	1.118	0.97
31_L	230_L	1.117	0.97
181_S	184_T	1.117	0.97
653_I	716_L	1.117	0.97
42_H	68_S	1.116	0.97
611_N	730_A	1.113	0.97
929_S	982_E	1.111	0.96
85_A	121_I	1.110	0.96
638_P	712_E	1.110	0.96
161_Y	249_A	1.109	0.96
273_T	281_D	1.108	0.96
787_K	825_P	1.103	0.96
977_L	988_A	1.101	0.96
97_I	121_I	1.100	0.96
832_F	846_L	1.098	0.96
820_A	836_V	1.096	0.96
752_M	769_Y	1.096	0.96
661_M	665_R	1.094	0.96
125_T	130_G	1.094	0.96
134_T	137_E	1.093	0.96
994_Q	998_L	1.092	0.96
200_E	481_K	1.089	0.96
328_F	399_V	1.088	0.96
413_T	493_A	1.087	0.96
43_V	102_Q	1.086	0.96
809_V	845_M	1.085	0.96
135_L	147_A	1.085	0.96
335_K	401_Q	1.083	0.96
1007_L	1031_L	1.083	0.96
338_V	388_P	1.080	0.96
283_L	355_L	1.080	0.96
7_Q	163_S	1.079	0.96
946_A	1014_C	1.076	0.96
23_E	26_S	1.076	0.96
229_D	235_E	1.076	0.96
669_F	695_H	1.071	0.96
287_C	350_L	1.071	0.96
136_L	141_F	1.071	0.96
291_L	302_Y	1.068	0.96
33_Y	233_L	1.067	0.96
110_K	113_W	1.067	0.96
624_L	652_V	1.062	0.95
206_R	222_A	1.062	0.95
670_S	673_E	1.062	0.95
156_G	159_A	1.062	0.95
152_Q	156_G	1.061	0.95
16_N	127_G	1.061	0.95
787_K	800_R	1.061	0.95
282_Y	286_I	1.060	0.95
29_D	58_G	1.059	0.95
412_I	510_Q	1.057	0.95
861_N	864_T	1.056	0.95
284_T	310_L	1.056	0.95
148_S	180_L	1.055	0.95
104_K	113_W	1.053	0.95
853_G	924_S	1.049	0.95
427_G	475_V	1.046	0.95
68_S	80_P	1.046	0.95
465_R	469_S	1.045	0.95
287_C	354_V	1.043	0.95
66_T	80_P	1.043	0.95
308_Y	370_E	1.041	0.95
611_N	737_G	1.041	0.95
552_I	743_L	1.040	0.95
131_Y	151_F	1.040	0.95
587_L	734_S	1.040	0.95
142_E	146_Q	1.039	0.95
462_L	476_Y	1.038	0.95
19_A	24_L	1.036	0.95
783_P	806_I	1.036	0.95
666_M	705_Y	1.035	0.95
994_Q	1025_M	1.034	0.95
447_R	450_M	1.030	0.95
419_A	483_E	1.030	0.95
771_Y	775_G	1.030	0.95
409_A	519_T	1.028	0.95
176_Q	179_K	1.026	0.94
545_I	739_Q	1.026	0.94
963_I	977_L	1.024	0.94
1001_V	1030_L	1.021	0.94
100_V	117_Y	1.019	0.94
690_D	718_V	1.019	0.94
145_A	180_L	1.019	0.94
573_F	738_C	1.019	0.94
972_Q	993_E	1.018	0.94
430_F	478_I	1.018	0.94
86_K	161_Y	1.017	0.94
972_Q	996_R	1.017	0.94
164_Y	243_H	1.017	0.94
785_V	832_F	1.015	0.94
123_A	155_F	1.012	0.94
389_D	541_N	1.011	0.94
708_D	712_E	1.011	0.94
979_L	1010_T	1.010	0.94
398_Y	402_K	1.010	0.94
287_C	291_L	1.007	0.94
641_D	665_R	1.007	0.94
671_L	679_R	1.006	0.94
92_Q	505_D	1.004	0.94
139_G	172_V	1.004	0.94
965_T	973_N	1.004	0.94
575_L	578_K	1.004	0.94
190_A	246_A	1.003	0.94
956_L	1023_F	1.003	0.94
45_Y	102_Q	1.003	0.94
422_A	479_A	1.002	0.94
830_F	898_P	1.002	0.94
162_F	186_I	1.001	0.94
786_N	824_K	1.001	0.94
507_V	519_T	1.000	0.94
111_P	151_F	0.999	0.94
22_E	57_R	0.999	0.94
96_K	504_T	0.997	0.94
346_A	352_A	0.996	0.94
928_L	935_L	0.996	0.94
388_P	543_T	0.995	0.94
20_A	485_L	0.995	0.94
816_D	820_A	0.995	0.94
689_L	718_V	0.994	0.94
23_E	201_D	0.994	0.94
476_Y	480_R	0.993	0.93
786_N	826_F	0.993	0.93
16_N	80_P	0.991	0.93
974_M	989_V	0.990	0.93
1008_L	1028_A	0.989	0.93
605_E	648_D	0.986	0.93
975_A	995_F	0.985	0.93
560_I	742_Y	0.985	0.93
587_L	737_G	0.984	0.93
932_R	982_E	0.983	0.93
177_I	188_V	0.982	0.93
576_L	611_N	0.980	0.93
135_L	143_Q	0.978	0.93
156_G	186_I	0.978	0.93
122_I	256_Q	0.976	0.93
580_D	772_E	0.975	0.93
685_K	688_I	0.974	0.93
48_I	261_V	0.973	0.93
645_I	662_I	0.973	0.93
582_T	769_Y	0.973	0.93
9_H	16_N	0.972	0.93
100_V	113_W	0.972	0.93
84_L	124_I	0.971	0.93
62_I	84_L	0.970	0.93
781_L	795_E	0.970	0.93
639_H	709_T	0.967	0.93
595_V	626_I	0.967	0.93
600_K	630_H	0.965	0.92
1016_V	1019_D	0.965	0.92
631_G	634_P	0.965	0.92
282_Y	326_W	0.961	0.92
159_A	256_Q	0.960	0.92
149_L	153_S	0.960	0.92
456_R	476_Y	0.960	0.92
755_L	769_Y	0.960	0.92
103_S	511_E	0.959	0.92
783_P	803_L	0.958	0.92
549_T	560_I	0.958	0.92
565_I	739_Q	0.957	0.92
295_F	361_D	0.955	0.92
253_I	257_C	0.955	0.92
31_L	233_L	0.955	0.92
752_M	799_V	0.955	0.92
432_V	436_E	0.954	0.92
814_V	817_I	0.954	0.92
827_E	831_D	0.953	0.92
587_L	596_L	0.952	0.92
908_L	925_N	0.952	0.92
790_F	804_R	0.952	0.92
942_S	983_T	0.951	0.92
620_E	719_K	0.951	0.92
791_P	804_R	0.950	0.92
579_G	614_Y	0.950	0.92
990_V	1025_M	0.949	0.92
148_S	160_F	0.947	0.92
232_P	235_E	0.944	0.92
290_G	294_R	0.942	0.92
111_P	131_Y	0.942	0.92
99_S	103_S	0.940	0.91
336_G	546_E	0.939	0.91
9_H	66_T	0.937	0.91
666_M	700_C	0.937	0.91
553_E	560_I	0.935	0.91
143_Q	147_A	0.935	0.91
497_V	519_T	0.935	0.91
250_S	254_A	0.931	0.91
750_Y	794_V	0.929	0.91
330_K	356_Y	0.927	0.91
852_S	918_T	0.925	0.91
813_A	845_M	0.924	0.91
447_R	454_E	0.924	0.91
82_V	124_I	0.923	0.91
545_I	549_T	0.921	0.91
80_P	195_H	0.921	0.91
348_G	728_S	0.921	0.91
824_K	827_E	0.921	0.91
83_L	121_I	0.920	0.91
90_G	93_N	0.920	0.91
636_H	712_E	0.920	0.91
127_G	195_H	0.920	0.91
681_V	689_L	0.918	0.90
830_F	872_A	0.918	0.90
676_L	692_E	0.915	0.90
451_T	454_E	0.913	0.90
164_Y	246_A	0.912	0.90
753_C	757_T	0.911	0.90
570_D	577_S	0.911	0.90
422_A	452_L	0.910	0.90
864_T	901_V	0.910	0.90
278_S	314_K	0.909	0.90
282_Y	285_D	0.909	0.90
400_Q	405_A	0.909	0.90
118_R	154_I	0.908	0.90
26_S	53_A	0.908	0.90
990_V	1028_A	0.904	0.90
954_L	1023_F	0.904	0.90
266_T	318_F	0.904	0.90
605_E	727_R	0.902	0.90
103_S	517_Y	0.901	0.90
1003_R	1006_A	0.901	0.90
641_D	666_M	0.901	0.90
54_C	58_G	0.900	0.90
368_L	728_S	0.899	0.90
698_E	701_L	0.899	0.90
267_R	500_E	0.897	0.89
785_V	855_M	0.897	0.89
859_G	865_L	0.897	0.89
87_S	119_E	0.895	0.89
65_L	121_I	0.895	0.89
333_H	359_D	0.894	0.89
41_D	68_S	0.894	0.89
199_K	229_D	0.893	0.89
44_M	121_I	0.893	0.89
36_L	59_I	0.891	0.89
582_T	772_E	0.891	0.89
8_V	24_L	0.889	0.89
968_T	972_Q	0.887	0.89
687_E	690_D	0.883	0.89
332_A	387_F	0.882	0.89
187_P	256_Q	0.880	0.89
860_Q	865_L	0.879	0.88
336_G	550_S	0.879	0.88
8_V	194_V	0.878	0.88
697_V	707_V	0.878	0.88
623_P	730_A	0.877	0.88
26_S	30_R	0.877	0.88
51_Y	262_S	0.875	0.88
792_F	805_A	0.875	0.88
772_E	775_G	0.875	0.88
34_A	255_E	0.875	0.88
910_D	914_F	0.872	0.88
972_Q	992_P	0.871	0.88
333_H	339_T	0.869	0.88
664_S	674_A	0.867	0.88
843_R	847_E	0.867	0.88
35_S	60_N	0.867	0.88
192_G	236_M	0.867	0.88
181_S	188_V	0.864	0.88
668_G	702_K	0.863	0.88
4_V	254_A	0.862	0.88
690_D	694_S	0.861	0.87
673_E	699_G	0.861	0.87
499_S	502_P	0.860	0.87
809_V	814_V	0.860	0.87
35_S	59_I	0.858	0.87
1001_V	1008_L	0.857	0.87
639_H	705_Y	0.856	0.87
42_H	101_L	0.856	0.87
906_L	914_F	0.855	0.87
456_R	463_D	0.855	0.87
757_T	791_P	0.854	0.87
851_F	866_L	0.854	0.87
364_K	567_Y	0.854	0.87
843_R	870_D	0.853	0.87
549_T	552_I	0.853	0.87
824_K	835_R	0.851	0.87
439_Q	465_R	0.849	0.87
573_F	603_G	0.849	0.87
551_M	750_Y	0.849	0.87
785_V	854_A	0.848	0.87
273_T	277_T	0.847	0.87
29_D	59_I	0.847	0.87
7_Q	191_T	0.846	0.87
55_K	262_S	0.845	0.86
335_K	391_R	0.844	0.86
40_D	46_G	0.844	0.86
165_Q	191_T	0.843	0.86
863_A	906_L	0.843	0.86
856_D	862_R	0.842	0.86
152_Q	184_T	0.841	0.86
215_E	223_E	0.841	0.86
102_Q	510_Q	0.840	0.86
661_M	664_S	0.837	0.86
653_I	717_I	0.837	0.86
681_V	717_I	0.836	0.86
454_E	458_Q	0.836	0.86
553_E	558_I	0.835	0.86
609_A	650_Y	0.832	0.86
216_K	429_V	0.831	0.86
443_L	459_S	0.831	0.86
773_A	780_I	0.830	0.85
569_D	572_T	0.830	0.85
434_P	437_A	0.829	0.85
51_Y	260_D	0.828	0.85
552_I	750_Y	0.827	0.85
18_A	485_L	0.826	0.85
968_T	989_V	0.824	0.85
851_F	917_E	0.823	0.85
210_A	429_V	0.822	0.85
245_E	249_A	0.822	0.85
195_H	205_Y	0.822	0.85
592_M	614_Y	0.820	0.85
986_M	1023_F	0.820	0.85
566_S	746_H	0.819	0.85
1030_L	1033_D	0.818	0.85
654_V	722_N	0.816	0.84
440_L	465_R	0.816	0.84
953_Q	1011_A	0.816	0.84
609_A	625_F	0.815	0.84
819_K	822_K	0.814	0.84
48_I	259_V	0.813	0.84
672_G	679_R	0.812	0.84
812_S	815_K	0.811	0.84
238_N	241_R	0.810	0.84
98_S	102_Q	0.810	0.84
70_F	110_K	0.810	0.84
660_M	728_S	0.810	0.84
89_T	92_Q	0.809	0.84
594_S	597_K	0.809	0.84
390_T	543_T	0.809	0.84
710_A	714_Y	0.808	0.84
123_A	160_F	0.808	0.84
622_I	654_V	0.807	0.84
82_V	123_A	0.806	0.84
644_S	647_E	0.806	0.84
411_I	493_A	0.805	0.84
218_T	471_L	0.804	0.84
329_M	333_H	0.803	0.84
846_L	869_I	0.802	0.83
1025_M	1028_A	0.801	0.83
552_I	747_Y	0.800	0.83
575_L	584_I	0.799	0.83
289_E	292_R	0.798	0.83
1010_T	1028_A	0.798	0.83
9_H	195_H	0.797	0.83
25_V	29_D	0.797	0.83
455_A	462_L	0.797	0.83
331_H	334_E	0.796	0.83
6_L	253_I	0.795	0.83
274_P	281_D	0.795	0.83
211_I	426_V	0.794	0.83
998_L	1027_R	0.794	0.83
432_V	437_A	0.792	0.83
625_F	635_V	0.792	0.83
162_F	177_I	0.791	0.83
595_V	598_R	0.791	0.83
460_P	464_K	0.791	0.83
240_Y	244_P	0.791	0.83
316_M	375_P	0.791	0.83
432_V	471_L	0.790	0.83
415_G	421_A	0.790	0.83
551_M	555_E	0.789	0.82
173_L	177_I	0.788	0.82
360_V	735_M	0.788	0.82
440_L	472_L	0.787	0.82
205_Y	225_L	0.787	0.82
304_R	308_Y	0.786	0.82
494_A	523_M	0.786	0.82
41_D	195_H	0.786	0.82
976_F	1022_Q	0.786	0.82
36_L	194_V	0.785	0.82
69_V	109_L	0.785	0.82
16_N	195_H	0.784	0.82
328_F	385_I	0.783	0.82
356_Y	359_D	0.783	0.82
977_L	1002_L	0.782	0.82
251_V	254_A	0.782	0.82
908_L	911_L	0.782	0.82
97_I	113_W	0.780	0.82
291_L	350_L	0.780	0.82
747_Y	750_Y	0.780	0.82
576_L	584_I	0.779	0.82
346_A	726_N	0.779	0.82
128_E	173_L	0.778	0.82
209_K	213_A	0.777	0.81
426_V	482_I	0.777	0.81
450_M	455_A	0.777	0.81
965_T	999_S	0.776	0.81
44_M	63_I	0.776	0.81
808_S	848_A	0.775	0.81
436_E	469_S	0.775	0.81
229_D	232_P	0.774	0.81
693_R	697_V	0.774	0.81
577_S	730_A	0.773	0.81
91_Y	95_L	0.771	0.81
456_R	466_L	0.771	0.81
638_P	716_L	0.771	0.81
575_L	581_T	0.771	0.81
195_H	225_L	0.770	0.81
93_N	117_Y	0.770	0.81
268_L	380_M	0.770	0.81
671_L	676_L	0.768	0.81
759_V	766_I	0.768	0.81
207_C	429_V	0.768	0.81
595_V	622_I	0.767	0.81
919_L	923_F	0.767	0.81
610_V	737_G	0.766	0.81
54_C	59_I	0.766	0.81
208_L	485_L	0.766	0.81
944_L	983_T	0.766	0.81
551_M	794_V	0.766	0.81
990_V	994_Q	0.766	0.81
770_L	921_I	0.765	0.80
283_L	351_V	0.764	0.80
25_V	28_A	0.764	0.80
627_D	631_G	0.763	0.80
420_K	446_S	0.762	0.80
810_G	813_A	0.761	0.80
423_L	441_A	0.761	0.80
12_Y	49_Q	0.761	0.80
273_T	278_S	0.759	0.80
681_V	714_Y	0.758	0.80
437_A	475_V	0.757	0.80
502_P	505_D	0.757	0.80
863_A	905_E	0.756	0.80
122_I	253_I	0.756	0.80
60_N	255_E	0.756	0.80
943_I	984_G	0.755	0.80
1015_E	1024_I	0.754	0.80
23_E	198_R	0.754	0.80
554_K	789_S	0.753	0.79
861_N	911_L	0.751	0.79
190_A	240_Y	0.751	0.79
620_E	730_A	0.751	0.79
846_L	873_L	0.750	0.79
843_R	873_L	0.747	0.79
79_Y	131_Y	0.746	0.79
624_L	628_R	0.745	0.79
604_L	607_I	0.744	0.79
51_Y	259_V	0.744	0.79
581_T	593_R	0.744	0.79
267_R	501_E	0.743	0.79
719_K	722_N	0.743	0.79
96_K	502_P	0.742	0.78
156_G	187_P	0.742	0.78
136_L	173_L	0.742	0.78
436_E	472_L	0.739	0.78
178_L	182_E	0.739	0.78
288_M	292_R	0.739	0.78
491_T	518_L	0.738	0.78
859_G	864_T	0.737	0.78
599_L	630_H	0.737	0.78
187_P	249_A	0.737	0.78
100_V	103_S	0.736	0.78
311_D	314_K	0.736	0.78
71_T	78_A	0.736	0.78
291_L	299_D	0.736	0.78
203_A	478_I	0.735	0.78
784_S	800_R	0.735	0.78
975_A	1002_L	0.735	0.78
573_F	576_L	0.735	0.78
413_T	490_S	0.735	0.78
233_L	247_L	0.734	0.78
621_N	730_A	0.734	0.78
749_L	794_V	0.734	0.78
669_F	699_G	0.733	0.78
714_Y	718_V	0.732	0.77
553_E	556_E	0.732	0.77
236_M	240_Y	0.731	0.77
282_Y	289_E	0.731	0.77
271_F	326_W	0.730	0.77
316_M	380_M	0.728	0.77
39_T	64_G	0.728	0.77
989_V	1015_E	0.728	0.77
187_P	245_E	0.727	0.77
364_K	568_S	0.726	0.77
27_E	232_P	0.726	0.77
51_Y	63_I	0.726	0.77
590_A	594_S	0.725	0.77
86_K	122_I	0.724	0.77
49_Q	522_A	0.723	0.77
205_Y	209_K	0.723	0.77
976_F	987_E	0.722	0.77
18_A	208_L	0.721	0.76
814_V	818_Y	0.721	0.76
209_K	212_K	0.720	0.76
248_Q	252_E	0.720	0.76
992_P	995_F	0.719	0.76
1011_A	1029_E	0.719	0.76
611_N	654_V	0.719	0.76
908_L	929_S	0.719	0.76
554_K	557_N	0.718	0.76
1009_F	1031_L	0.718	0.76
73_D	110_K	0.717	0.76
123_A	154_I	0.716	0.76
84_L	253_I	0.716	0.76
705_Y	709_T	0.716	0.76
141_F	145_A	0.715	0.76
189_T	250_S	0.713	0.76
620_E	722_N	0.713	0.76
976_F	1024_I	0.713	0.76
593_R	596_L	0.713	0.76
940_A	957_G	0.713	0.76
420_K	427_G	0.713	0.76
864_T	868_S	0.712	0.76
48_I	529_L	0.712	0.76
190_A	244_P	0.712	0.76
3_F	192_G	0.711	0.75
696_F	700_C	0.710	0.75
974_M	992_P	0.709	0.75
301_R	363_I	0.709	0.75
551_M	753_C	0.709	0.75
298_P	302_Y	0.708	0.75
622_I	652_V	0.708	0.75
112_K	116_S	0.707	0.75
132_I	162_F	0.707	0.75
149_L	152_Q	0.707	0.75
97_I	109_L	0.707	0.75
599_L	610_V	0.707	0.75
700_C	703_K	0.706	0.75
189_T	254_A	0.706	0.75
809_V	852_S	0.706	0.75
967_R	973_N	0.706	0.75
24_L	230_L	0.705	0.75
766_I	792_F	0.705	0.75
887_G	890_L	0.705	0.75
422_A	426_V	0.705	0.75
286_I	330_K	0.704	0.75
339_T	387_F	0.704	0.75
469_S	472_L	0.704	0.75
196_Y	202_K	0.703	0.75
875_H	898_P	0.703	0.75
335_K	395_V	0.703	0.75
28_A	54_C	0.702	0.74
545_I	548_I	0.702	0.74
96_K	117_Y	0.702	0.74
628_R	650_Y	0.700	0.74
270_S	279_A	0.699	0.74
69_V	81_L	0.698	0.74
598_R	626_I	0.698	0.74
608_V	730_A	0.698	0.74
364_K	605_E	0.697	0.74
841_V	845_M	0.697	0.74
128_E	170_N	0.697	0.74
813_A	841_V	0.697	0.74
254_A	257_C	0.695	0.74
328_F	536_F	0.695	0.74
235_E	238_N	0.695	0.74
606_D	629_K	0.695	0.74
855_M	858_F	0.693	0.74
816_D	819_K	0.692	0.73
103_S	509_L	0.691	0.73
62_I	254_A	0.690	0.73
146_Q	150_E	0.690	0.73
471_L	474_Q	0.690	0.73
24_L	36_L	0.689	0.73
512_G	518_L	0.688	0.73
860_Q	864_T	0.688	0.73
81_L	151_F	0.688	0.73
245_E	248_Q	0.688	0.73
85_A	120_G	0.688	0.73
784_S	787_K	0.688	0.73
748_P	776_S	0.687	0.73
568_S	738_C	0.687	0.73
503_L	509_L	0.685	0.73
273_T	276_G	0.685	0.73
16_N	66_T	0.684	0.73
326_W	331_H	0.683	0.72
852_S	855_M	0.682	0.72
425_D	428_R	0.682	0.72
320_D	532_L	0.682	0.72
295_F	299_D	0.681	0.72
607_I	611_N	0.680	0.72
5_H	236_M	0.679	0.72
576_L	596_L	0.679	0.72
390_T	546_E	0.679	0.72
611_N	735_M	0.677	0.72
549_T	565_I	0.676	0.72
175_E	179_K	0.675	0.72
7_Q	82_V	0.674	0.71
705_Y	713_V	0.674	0.71
635_V	650_Y	0.673	0.71
687_E	691_R	0.673	0.71
547_S	758_S	0.673	0.71
993_E	997_Q	0.673	0.71
296_G	299_D	0.672	0.71
322_F	383_I	0.672	0.71
427_G	430_F	0.672	0.71
670_S	695_H	0.672	0.71
675_D	678_R	0.671	0.71
10_S	47_A	0.670	0.71
949_A	952_R	0.670	0.71
1011_A	1026_S	0.670	0.71
436_E	439_Q	0.670	0.71
301_R	304_R	0.669	0.71
47_A	521_Y	0.668	0.71
247_L	251_V	0.668	0.71
950_V	1015_E	0.668	0.71
411_I	527_E	0.668	0.71
9_H	13_S	0.668	0.71
909_V	930_A	0.667	0.71
118_R	159_A	0.667	0.71
753_C	794_V	0.666	0.71
853_G	856_D	0.666	0.71
547_S	791_P	0.666	0.71
44_M	94_L	0.665	0.70
433_S	436_E	0.665	0.70
193_D	205_Y	0.665	0.70
861_N	904_E	0.665	0.70
182_E	185_G	0.665	0.70
789_S	818_Y	0.665	0.70
73_D	112_K	0.665	0.70
190_A	247_L	0.664	0.70
503_L	507_V	0.664	0.70
1006_A	1030_L	0.664	0.70
162_F	175_E	0.664	0.70
595_V	730_A	0.663	0.70
331_H	394_E	0.663	0.70
31_L	234_E	0.662	0.70
552_I	558_I	0.662	0.70
118_R	156_G	0.662	0.70
757_T	760_I	0.662	0.70
1017_R	1022_Q	0.662	0.70
132_I	147_A	0.662	0.70
598_R	627_D	0.661	0.70
38_L	63_I	0.661	0.70
126_P	163_S	0.660	0.70
932_R	936_T	0.660	0.70
576_L	610_V	0.660	0.70
23_E	197_I	0.660	0.70
472_L	475_V	0.659	0.70
7_Q	195_H	0.658	0.70
978_T	985_E	0.657	0.70
510_Q	518_L	0.657	0.70
166_P	243_H	0.657	0.70
62_I	799_V	0.657	0.70
934_Q	938_Q	0.656	0.69
236_M	239_I	0.656	0.69
456_R	459_S	0.656	0.69
64_G	84_L	0.655	0.69
872_A	876_A	0.655	0.69
600_K	632_R	0.655	0.69
188_V	249_A	0.654	0.69
66_T	195_H	0.654	0.69
28_A	31_L	0.654	0.69
97_I	100_V	0.654	0.69
7_Q	80_P	0.653	0.69
998_L	1001_V	0.653	0.69
946_A	986_M	0.652	0.69
575_L	607_I	0.652	0.69
964_K	976_F	0.651	0.69
489_A	510_Q	0.650	0.69
521_Y	525_H	0.649	0.69
969_K	991_F	0.649	0.69
1014_C	1021_I	0.648	0.68
388_P	546_E	0.648	0.68
19_A	230_L	0.648	0.68
410_Q	496_V	0.648	0.68
572_T	742_Y	0.648	0.68
790_F	818_Y	0.647	0.68
174_S	177_I	0.647	0.68
304_R	307_Q	0.647	0.68
49_Q	53_A	0.647	0.68
626_I	629_K	0.646	0.68
154_I	157_K	0.646	0.68
465_R	472_L	0.646	0.68
419_A	448_P	0.646	0.68
818_Y	826_F	0.645	0.68
27_E	230_L	0.644	0.68
628_R	632_R	0.644	0.68
822_K	825_P	0.643	0.68
161_Y	187_P	0.643	0.68
625_F	650_Y	0.642	0.68
294_R	354_V	0.642	0.68
511_E	517_Y	0.641	0.68
844_K	848_A	0.641	0.68
332_A	395_V	0.641	0.68
644_S	648_D	0.640	0.68
7_Q	193_D	0.639	0.67
621_N	716_L	0.639	0.67
28_A	233_L	0.639	0.67
210_A	217_L	0.638	0.67
603_G	608_V	0.638	0.67
127_G	213_A	0.638	0.67
33_Y	230_L	0.638	0.67
188_V	243_H	0.637	0.67
998_L	1025_M	0.637	0.67
127_G	133_E	0.636	0.67
9_H	163_S	0.635	0.67
336_G	391_R	0.635	0.67
3_F	6_L	0.634	0.67
731_V	735_M	0.634	0.67
693_R	714_Y	0.634	0.67
375_P	672_G	0.634	0.67
576_L	737_G	0.634	0.67
359_D	739_Q	0.633	0.67
137_E	169_G	0.632	0.67
966_I	989_V	0.630	0.66
398_Y	401_Q	0.630	0.66
41_D	66_T	0.630	0.66
206_R	216_K	0.629	0.66
541_N	755_L	0.629	0.66
87_S	258_R	0.629	0.66
990_V	1002_L	0.629	0.66
9_H	41_D	0.629	0.66
549_T	562_L	0.629	0.66
268_L	324_I	0.629	0.66
81_L	123_A	0.628	0.66
765_K	768_Q	0.628	0.66
452_L	476_Y	0.627	0.66
211_I	429_V	0.627	0.66
197_I	201_D	0.627	0.66
305_R	367_L	0.627	0.66
679_R	732_A	0.626	0.66
38_L	46_G	0.624	0.66
51_Y	55_K	0.624	0.66
220_A	224_D	0.622	0.65
595_V	621_N	0.622	0.65
979_L	986_M	0.621	0.65
88_N	267_R	0.621	0.65
556_E	560_I	0.620	0.65
912_L	925_N	0.620	0.65
288_M	310_L	0.620	0.65
19_A	194_V	0.619	0.65
283_L	314_K	0.619	0.65
695_H	698_E	0.619	0.65
292_R	297_K	0.619	0.65
301_R	305_R	0.619	0.65
995_F	999_S	0.619	0.65
2_S	251_V	0.618	0.65
65_L	83_L	0.618	0.65
399_V	498_L	0.617	0.65
430_F	475_V	0.617	0.65
817_I	841_V	0.617	0.65
164_Y	177_I	0.616	0.65
10_S	25_V	0.616	0.65
328_F	395_V	0.615	0.64
164_Y	181_S	0.615	0.64
172_V	176_Q	0.614	0.64
549_T	561_D	0.614	0.64
190_A	241_R	0.613	0.64
908_L	930_A	0.613	0.64
48_I	263_L	0.613	0.64
549_T	743_L	0.613	0.64
11_G	208_L	0.613	0.64
523_M	595_V	0.613	0.64
785_V	803_L	0.613	0.64
669_F	680_A	0.612	0.64
856_D	911_L	0.612	0.64
968_T	1012_G	0.612	0.64
957_G	1009_F	0.612	0.64
609_A	655_Y	0.611	0.64
690_D	693_R	0.610	0.64
545_I	736_I	0.610	0.64
987_E	1022_Q	0.609	0.64
994_Q	997_Q	0.609	0.64
576_L	741_A	0.608	0.64
219_D	223_E	0.608	0.64
166_P	174_S	0.607	0.63
378_V	672_G	0.606	0.63
164_Y	188_V	0.606	0.63
11_G	486_P	0.606	0.63
69_V	114_L	0.606	0.63
307_Q	1027_R	0.606	0.63
672_G	676_L	0.605	0.63
164_Y	190_A	0.605	0.63
411_I	494_A	0.605	0.63
366_H	647_E	0.605	0.63
86_K	258_R	0.604	0.63
54_C	57_R	0.604	0.63
447_R	458_Q	0.604	0.63
198_R	201_D	0.604	0.63
936_T	945_Q	0.603	0.63
638_P	644_S	0.603	0.63
63_I	261_V	0.602	0.63
146_Q	149_L	0.602	0.63
950_V	1016_V	0.602	0.63
214_G	429_V	0.602	0.63
437_A	441_A	0.601	0.63
501_E	506_V	0.601	0.63
910_D	913_A	0.600	0.63
742_Y	747_Y	0.600	0.63
669_F	714_Y	0.600	0.63
443_L	465_R	0.599	0.62
548_I	552_I	0.599	0.62
808_S	844_K	0.599	0.62
689_L	717_I	0.599	0.62
689_L	714_Y	0.599	0.62
350_L	353_Y	0.599	0.62
67_A	97_I	0.599	0.62
833_C	846_L	0.598	0.62
590_A	987_E	0.598	0.62
440_L	475_V	0.598	0.62
595_V	623_P	0.598	0.62
621_N	652_V	0.597	0.62
625_F	628_R	0.596	0.62
700_C	710_A	0.596	0.62
21_V	25_V	0.596	0.62
809_V	813_A	0.595	0.62
975_A	992_P	0.594	0.62
152_Q	160_F	0.594	0.62
786_N	857_E	0.593	0.62
22_E	49_Q	0.593	0.62
7_Q	165_Q	0.593	0.62
207_C	217_L	0.592	0.62
941_V	945_Q	0.592	0.62
66_T	163_S	0.592	0.62
951_K	1013_K	0.592	0.62
753_C	799_V	0.590	0.61
912_L	922_Y	0.590	0.61
826_F	835_R	0.590	0.61
407_H	503_L	0.590	0.61
318_F	532_L	0.589	0.61
1016_V	1021_I	0.589	0.61
210_A	220_A	0.589	0.61
70_F	108_G	0.589	0.61
454_E	457_Q	0.588	0.61
31_L	198_R	0.588	0.61
5_H	8_V	0.588	0.61
989_V	1024_I	0.588	0.61
68_S	127_G	0.587	0.61
322_F	355_L	0.587	0.61
26_S	29_D	0.587	0.61
826_F	836_V	0.586	0.61
197_I	230_L	0.586	0.61
452_L	480_R	0.586	0.61
131_Y	135_L	0.585	0.61
621_N	653_I	0.585	0.61
273_T	282_Y	0.585	0.61
432_V	472_L	0.585	0.61
718_V	722_N	0.585	0.61
276_G	281_D	0.585	0.61
407_H	502_P	0.584	0.60
114_L	117_Y	0.584	0.60
855_M	865_L	0.583	0.60
105_S	110_K	0.583	0.60
552_I	556_E	0.583	0.60
262_S	267_R	0.583	0.60
424_R	437_A	0.583	0.60
86_K	120_G	0.583	0.60
169_G	172_V	0.583	0.60
701_L	706_S	0.582	0.60
752_M	772_E	0.582	0.60
556_E	559_K	0.582	0.60
389_D	543_T	0.582	0.60
699_G	710_A	0.581	0.60
940_A	1009_F	0.581	0.60
836_V	840_S	0.581	0.60
698_E	707_V	0.581	0.60
782_P	800_R	0.580	0.60
320_D	682_S	0.580	0.60
573_F	587_L	0.580	0.60
101_L	107_G	0.579	0.60
69_V	151_F	0.579	0.60
105_S	108_G	0.579	0.60
864_T	902_E	0.579	0.60
52_K	56_A	0.579	0.60
909_V	1005_G	0.579	0.60
696_F	714_Y	0.578	0.60
785_V	814_V	0.578	0.60
190_A	236_M	0.577	0.60
778_I	799_V	0.577	0.60
7_Q	37_A	0.577	0.60
260_D	263_L	0.577	0.60
861_N	900_Y	0.576	0.59
512_G	516_I	0.576	0.59
578_K	745_A	0.576	0.59
1017_R	1020_K	0.576	0.59
818_Y	822_K	0.575	0.59
263_L	529_L	0.575	0.59
211_I	425_D	0.574	0.59
989_V	1021_I	0.574	0.59
661_M	679_R	0.574	0.59
519_T	526_L	0.574	0.59
112_K	115_H	0.573	0.59
864_T	903_T	0.573	0.59
415_G	488_H	0.573	0.59
499_S	503_L	0.573	0.59
755_L	758_S	0.572	0.59
25_V	59_I	0.572	0.59
419_A	452_L	0.572	0.59
249_A	253_I	0.571	0.59
968_T	991_F	0.571	0.59
178_L	246_A	0.571	0.59
176_Q	180_L	0.571	0.59
603_G	648_D	0.570	0.59
728_S	772_E	0.569	0.59
761_G	811_V	0.569	0.59
507_V	526_L	0.569	0.59
196_Y	228_L	0.569	0.59
167_F	192_G	0.569	0.59
671_L	730_A	0.569	0.59
790_F	814_V	0.569	0.59
181_S	185_G	0.569	0.59
956_L	986_M	0.569	0.59
210_A	213_A	0.569	0.59
1029_E	1034_M	0.569	0.59
170_N	173_L	0.569	0.59
22_E	26_S	0.569	0.59
88_N	260_D	0.568	0.58
133_E	136_L	0.568	0.58
633_A	636_H	0.568	0.58
922_Y	927_P	0.568	0.58
500_E	506_V	0.567	0.58
210_A	222_A	0.567	0.58
582_T	768_Q	0.567	0.58
850_I	866_L	0.567	0.58
281_D	285_D	0.566	0.58
203_A	477_S	0.566	0.58
180_L	184_T	0.565	0.58
623_P	627_D	0.565	0.58
104_K	112_K	0.565	0.58
355_L	383_I	0.565	0.58
579_G	593_R	0.564	0.58
828_D	858_F	0.564	0.58
338_V	549_T	0.563	0.58
394_E	401_Q	0.563	0.58
821_R	824_K	0.563	0.58
943_I	1012_G	0.562	0.58
5_H	33_Y	0.562	0.58
628_R	636_H	0.562	0.58
694_S	707_V	0.561	0.57
167_F	228_L	0.560	0.57
199_K	235_E	0.560	0.57
319_S	420_K	0.560	0.57
114_L	151_F	0.560	0.57
127_G	130_G	0.560	0.57
587_L	592_M	0.559	0.57
816_D	836_V	0.559	0.57
868_S	900_Y	0.559	0.57
619_M	719_K	0.559	0.57
368_L	660_M	0.559	0.57
914_F	917_E	0.559	0.57
477_S	480_R	0.558	0.57
284_T	303_L	0.557	0.57
832_F	836_V	0.557	0.57
1009_F	1034_M	0.557	0.57
42_H	107_G	0.556	0.57
669_F	689_L	0.556	0.57
450_M	458_Q	0.556	0.57
790_F	811_V	0.556	0.57
286_I	355_L	0.555	0.57
456_R	460_P	0.555	0.57
624_L	627_D	0.555	0.57
936_T	942_S	0.555	0.57
308_Y	312_V	0.554	0.57
661_M	751_F	0.553	0.56
96_K	100_V	0.553	0.56
167_F	170_N	0.551	0.56
376_E	679_R	0.551	0.56
338_V	546_E	0.551	0.56
7_Q	39_T	0.551	0.56
141_F	176_Q	0.551	0.56
724_G	732_A	0.550	0.56
548_I	736_I	0.550	0.56
716_L	724_G	0.550	0.56
126_P	130_G	0.549	0.56
134_T	138_G	0.549	0.56
989_V	992_P	0.549	0.56
860_Q	900_Y	0.549	0.56
451_T	455_A	0.549	0.56
818_Y	821_R	0.548	0.56
417_L	425_D	0.548	0.56
507_V	531_L	0.548	0.56
419_A	444_I	0.548	0.56
310_L	355_L	0.547	0.56
420_K	441_A	0.546	0.55
41_D	107_G	0.546	0.55
6_L	13_S	0.546	0.55
603_G	611_N	0.545	0.55
457_Q	463_D	0.545	0.55
596_L	611_N	0.545	0.55
466_L	472_L	0.544	0.55
478_I	481_K	0.544	0.55
508_P	521_Y	0.543	0.55
34_A	59_I	0.543	0.55
834_F	897_K	0.542	0.55
67_A	101_L	0.542	0.55
646_L	662_I	0.542	0.55
89_T	93_N	0.542	0.55
831_D	834_F	0.541	0.55
296_G	300_E	0.541	0.55
440_L	462_L	0.541	0.55
56_A	691_R	0.540	0.55
833_C	850_I	0.540	0.55
44_M	47_A	0.539	0.54
405_A	517_Y	0.538	0.54
394_E	397_Q	0.538	0.54
150_E	153_S	0.537	0.54
682_S	716_L	0.537	0.54
292_R	303_L	0.537	0.54
157_K	161_Y	0.537	0.54
397_Q	400_Q	0.537	0.54
378_V	679_R	0.537	0.54
867_A	903_T	0.536	0.54
452_L	459_S	0.536	0.54
541_N	740_L	0.535	0.54
9_H	191_T	0.535	0.54
466_L	480_R	0.535	0.54
45_Y	412_I	0.535	0.54
236_M	247_L	0.534	0.54
566_S	742_Y	0.534	0.54
808_S	845_M	0.533	0.54
756_L	921_I	0.533	0.54
638_P	665_R	0.532	0.54
863_A	904_E	0.532	0.54
742_Y	1024_I	0.532	0.54
16_N	163_S	0.532	0.54
291_L	296_G	0.532	0.54
676_L	688_I	0.532	0.54
809_V	848_A	0.532	0.54
42_H	67_A	0.532	0.54
3_F	33_Y	0.532	0.54
639_H	642_L	0.531	0.53
979_L	1008_L	0.531	0.53
673_E	692_E	0.530	0.53
116_S	119_E	0.530	0.53
525_H	528_D	0.530	0.53
373_L	399_V	0.529	0.53
922_Y	926_H	0.529	0.53
636_H	643_R	0.529	0.53
1015_E	1022_Q	0.528	0.53
332_A	339_T	0.528	0.53
638_P	709_T	0.528	0.53
166_P	240_Y	0.528	0.53
995_F	1002_L	0.528	0.53
423_L	475_V	0.528	0.53
24_L	28_A	0.527	0.53
144_A	180_L	0.527	0.53
407_H	499_S	0.527	0.53
756_L	788_S	0.526	0.53
88_N	262_S	0.526	0.53
697_V	710_A	0.526	0.53
499_S	732_A	0.525	0.53
322_F	346_A	0.525	0.53
619_M	654_V	0.524	0.52
42_H	108_G	0.524	0.52
541_N	610_V	0.524	0.52
19_A	36_L	0.524	0.52
350_L	363_I	0.524	0.52
250_S	253_I	0.524	0.52
167_F	239_I	0.524	0.52
142_E	145_A	0.523	0.52
967_R	971_G	0.523	0.52
477_S	481_K	0.523	0.52
662_I	717_I	0.523	0.52
164_Y	174_S	0.522	0.52
749_L	798_S	0.522	0.52
287_C	292_R	0.522	0.52
147_A	151_F	0.522	0.52
7_Q	16_N	0.520	0.52
124_I	127_G	0.520	0.52
669_F	693_R	0.520	0.52
14_L	488_H	0.520	0.52
302_Y	353_Y	0.519	0.52
1009_F	1029_E	0.519	0.52
8_V	36_L	0.518	0.52
80_P	193_D	0.518	0.52
25_V	36_L	0.517	0.51
611_N	621_N	0.517	0.51
346_A	534_M	0.517	0.51
621_N	624_L	0.516	0.51
499_S	506_V	0.516	0.51
626_I	630_H	0.516	0.51
507_V	521_Y	0.516	0.51
330_K	398_Y	0.516	0.51
556_E	749_L	0.516	0.51
957_G	1031_L	0.516	0.51
963_I	975_A	0.515	0.51
132_I	848_A	0.514	0.51
352_A	383_I	0.514	0.51
244_P	248_Q	0.514	0.51
432_V	474_Q	0.514	0.51
149_L	186_I	0.514	0.51
714_Y	724_G	0.514	0.51
579_G	597_K	0.513	0.51
728_S	732_A	0.513	0.51
6_L	12_Y	0.513	0.51
965_T	975_A	0.512	0.51
598_R	620_E	0.512	0.51
967_R	972_Q	0.512	0.51
816_D	840_S	0.512	0.51
629_K	650_Y	0.512	0.51
439_Q	443_L	0.511	0.51
677_L	682_S	0.511	0.51
544_L	769_Y	0.511	0.51
549_T	739_Q	0.510	0.51
584_I	745_A	0.510	0.51
679_R	721_A	0.510	0.51
913_A	1005_G	0.510	0.51
17_S	205_Y	0.510	0.51
69_V	79_Y	0.509	0.50
273_T	279_A	0.509	0.50
587_L	622_I	0.508	0.50
452_L	456_R	0.508	0.50
681_V	688_I	0.506	0.50
62_I	986_M	0.506	0.50
129_K	134_T	0.506	0.50
1029_E	1033_D	0.506	0.50
465_R	468_E	0.505	0.50
74_S	77_E	0.504	0.50
247_L	250_S	0.504	0.50
813_A	842_N	0.504	0.50
665_R	703_K	0.504	0.50
230_L	461_Q	0.503	0.50
455_A	460_P	0.503	0.50
125_T	191_T	0.503	0.50
191_T	236_M	0.503	0.50
541_N	736_I	0.503	0.50
673_E	677_L	0.503	0.50
124_I	191_T	0.503	0.50
652_V	724_G	0.503	0.50
830_F	900_Y	0.502	0.49
946_A	954_L	0.502	0.49
552_I	560_I	0.502	0.49
573_F	577_S	0.502	0.49
51_Y	263_L	0.501	0.49
329_M	395_V	0.501	0.49
787_K	857_E	0.501	0.49
37_A	62_I	0.500	0.49
407_H	501_E	0.500	0.49
434_P	441_A	0.500	0.49

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2hpiA	2	0.9525	100	0.117	Contact Map
2hnhA	1	0.7848	100	0.245	Contact Map
3f2bA	1	0.6915	100	0.399	Contact Map
4gx8A	1	0.2323	100	0.845	Contact Map
3e38A	4	0.2493	100	0.886	Contact Map
3dcpA	1	0.1874	100	0.936	Contact Map
2yxoA	3	0.2036	99.9	0.939	Contact Map
3b0xA	1	0.2	99.9	0.945	Contact Map
3o0fA	1	0.1973	99.9	0.945	Contact Map
2w9mA	1	0.1991	99.9	0.945	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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