YTNA - BACSU - GREMLIN Contacts

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YTNA - Uncharacterized amino acid permease YtnA

UniProt:	O34618	Sequences: MQKQKQELHRGLEERHISLMSLGAAIGVGLFLGSASAIQLAGPGILVAYAASGLVMFFIMRALGEMAIQKPVAGSFSRYARDYLGPLAGYLTGWNYWFLWVVTCMAEITAVGIYMGFWFPDVPNWIWALSALVIMTGVNFLAVKAYGELEFWFALIKIVAILSMIAVGLLMIIAGVGNGGIATGISNLWNNGGFFPHGLKGVLLSLQMVMFAYLGIEMIGVTAGEVKNPQKSLAKAIDTVFWRILIFYVGALFVIMSIYPWQEIGSQGSPFVLTFQKVGIPSAAGIINFVVLTAALSSCNSGIFSTGRMLFNLAEQKEAPQAYGQLTKGGIPGKAVLASAGALLVGVLLNYVVPAKVFTWVTSIATFGAIWTWAIILLSQIKYRKSLKPEEKKQLKYKMPLFPFTSYVSLAFLAFVVILMAYSPDTRVAVIIGPIWFLILLAVYYGKGFHKKNAAAASERNIS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	463 (421)
Sequences:	24752 (15866)
Seq/√Len:	773.2

ECOLI - PROY YIFK AROP GABP ANSP LYSP PHEP PLAP MMUP PUUP FRLA CYCA ADIC POTE GADC YBAT YCAM YGJI CADB YJEM ARCD YJEH TNAB
BACSU - YTNA GABP YBXG ROCC YVBW YDGF AAPA HUTM YBGF ROCE STET YCGH ASPP YHDG YBEC YFNA ARCD YECA YDAO GERBB YNDE GERAB GERKB YFKT
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97U05 Q97XM0 Q97X49 Q7LXI7 Q97WS3 Q97ZB5 Q97Z63 Q97VA6 Q97U33 Q97WD4 Q97VA8 Q97VR4 Q97Y76 Q97YX9 Q97YN3 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
136_T	340_A	4.463	1.00
322_A	334_K	4.416	1.00
382_K	386_S	3.434	1.00
374_A	410_L	3.305	1.00
53_G	245_L	3.297	1.00
325_Q	334_K	3.155	1.00
231_K	235_K	3.128	1.00
13_E	227_K	2.906	1.00
77_S	316_Q	2.808	1.00
226_V	232_S	2.806	1.00
93_G	313_L	2.694	1.00
314_A	324_G	2.686	1.00
18_S	239_T	2.634	1.00
228_N	231_K	2.610	1.00
327_T	333_G	2.595	1.00
129_L	344_L	2.587	1.00
282_S	286_I	2.515	1.00
322_A	325_Q	2.505	1.00
14_E	239_T	2.405	1.00
224_G	315_E	2.377	1.00
377_L	409_S	2.355	1.00
168_G	254_V	2.335	1.00
65_E	384_R	2.290	1.00
337_L	341_G	2.243	1.00
81_R	89_G	2.215	1.00
225_E	308_R	2.204	1.00
311_F	315_E	2.194	1.00
137_G	141_L	2.179	1.00
133_V	344_L	2.161	1.00
436_W	440_L	2.156	1.00
166_A	170_L	2.151	1.00
17_I	226_V	2.113	1.00
14_E	232_S	2.109	1.00
136_T	336_V	2.104	1.00
273_L	276_Q	2.087	1.00
140_F	333_G	2.066	1.00
144_K	148_E	2.046	1.00
14_E	18_S	2.046	1.00
235_K	239_T	2.036	1.00
37_A	45_I	2.022	1.00
442_A	446_G	2.022	1.00
407_Y	411_A	2.021	1.00
18_S	243_R	2.019	1.00
128_A	347_V	2.000	1.00
84_L	382_K	1.997	1.00
155_L	159_V	1.987	1.00
13_E	16_H	1.975	1.00
323_Y	338_A	1.967	1.00
263_E	277_K	1.955	1.00
129_L	347_V	1.951	1.00
97_W	339_S	1.948	1.00
317_K	321_Q	1.945	1.00
62_A	377_L	1.936	1.00
81_R	86_P	1.935	1.00
8_L	326_L	1.909	1.00
84_L	378_L	1.889	1.00
260_P	263_E	1.886	1.00
122_V	125_W	1.873	1.00
378_L	410_L	1.872	1.00
54_L	58_F	1.871	1.00
327_T	331_I	1.823	1.00
411_A	415_F	1.817	1.00
85_G	88_A	1.808	1.00
133_V	340_A	1.799	1.00
404_F	408_V	1.779	1.00
228_N	232_S	1.767	1.00
273_L	277_K	1.742	1.00
391_E	395_L	1.742	1.00
238_D	242_W	1.736	1.00
80_A	92_T	1.720	1.00
16_H	151_F	1.714	1.00
139_N	300_N	1.714	1.00
12_L	16_H	1.708	1.00
132_L	343_L	1.701	1.00
21_S	240_V	1.701	1.00
140_F	337_L	1.696	1.00
55_V	412_F	1.690	1.00
92_T	375_I	1.686	1.00
94_W	440_L	1.681	1.00
159_V	163_S	1.667	1.00
48_A	205_S	1.653	1.00
104_C	343_L	1.650	1.00
329_G	333_G	1.646	1.00
44_G	202_V	1.646	1.00
108_I	299_C	1.638	1.00
434_P	438_L	1.626	1.00
382_K	385_K	1.616	1.00
115_M	127_W	1.562	1.00
276_Q	284_A	1.551	1.00
84_L	88_A	1.550	1.00
242_W	246_I	1.520	1.00
58_F	408_V	1.505	1.00
311_F	326_L	1.496	1.00
222_T	304_F	1.495	1.00
310_L	335_A	1.491	1.00
228_N	235_K	1.484	1.00
141_L	329_G	1.481	1.00
60_M	241_F	1.479	1.00
52_S	209_V	1.473	1.00
334_K	338_A	1.471	1.00
129_L	133_V	1.454	1.00
306_T	339_S	1.435	1.00
160_A	290_V	1.435	1.00
9_H	330_G	1.415	1.00
378_L	382_K	1.415	1.00
54_L	408_V	1.409	1.00
321_Q	324_G	1.407	1.00
80_A	375_I	1.406	1.00
44_G	195_F	1.405	1.00
229_P	234_A	1.404	1.00
321_Q	325_Q	1.398	1.00
132_L	340_A	1.393	1.00
8_L	311_F	1.388	1.00
108_I	132_L	1.387	1.00
136_T	337_L	1.387	1.00
325_Q	333_G	1.385	1.00
307_G	336_V	1.378	1.00
73_A	224_G	1.375	1.00
16_H	147_G	1.368	1.00
285_G	289_F	1.360	1.00
158_I	162_L	1.355	1.00
267_Q	273_L	1.336	1.00
169_L	254_V	1.333	1.00
12_L	17_I	1.332	1.00
164_M	168_G	1.329	1.00
276_Q	281_P	1.325	1.00
60_M	237_I	1.319	1.00
70_K	82_D	1.318	1.00
59_I	377_L	1.306	1.00
170_L	175_G	1.300	1.00
441_L	445_Y	1.300	1.00
246_I	250_G	1.299	1.00
72_V	78_R	1.292	1.00
415_F	419_L	1.285	1.00
111_V	292_L	1.284	1.00
83_Y	379_S	1.284	1.00
401_L	405_T	1.283	1.00
46_L	253_F	1.278	1.00
78_R	82_D	1.275	1.00
269_S	273_L	1.275	1.00
381_I	407_Y	1.274	1.00
69_Q	395_L	1.272	1.00
111_V	131_A	1.267	1.00
61_R	238_D	1.264	1.00
435_I	439_I	1.257	1.00
135_M	299_C	1.255	1.00
446_G	449_F	1.252	1.00
25_A	244_I	1.252	1.00
15_R	19_L	1.247	1.00
12_L	147_G	1.241	1.00
232_S	235_K	1.238	1.00
107_E	298_S	1.236	1.00
431_I	435_I	1.229	1.00
62_A	406_S	1.228	1.00
443_V	447_K	1.223	1.00
14_E	235_K	1.221	1.00
172_I	257_S	1.219	1.00
97_W	310_L	1.215	1.00
72_V	82_D	1.212	1.00
173_I	176_V	1.205	1.00
87_L	447_K	1.205	1.00
227_K	232_S	1.195	1.00
374_A	414_A	1.193	1.00
392_K	395_L	1.191	1.00
310_L	319_A	1.185	1.00
138_V	149_L	1.182	1.00
17_I	236_A	1.180	1.00
385_K	403_P	1.175	1.00
445_Y	449_F	1.164	1.00
32_L	110_A	1.162	1.00
21_S	219_I	1.157	1.00
443_V	446_G	1.139	1.00
165_I	250_G	1.138	1.00
149_L	153_F	1.136	1.00
63_L	76_F	1.130	1.00
20_M	222_T	1.127	1.00
169_L	173_I	1.126	1.00
126_I	130_S	1.119	1.00
402_F	406_S	1.119	1.00
77_S	312_N	1.116	1.00
22_L	243_R	1.111	1.00
150_E	300_N	1.107	1.00
11_G	227_K	1.094	1.00
404_F	407_Y	1.092	1.00
315_E	324_G	1.092	1.00
326_L	330_G	1.088	1.00
82_D	387_L	1.087	1.00
401_L	404_F	1.082	1.00
403_P	407_Y	1.078	1.00
67_A	79_Y	1.074	1.00
380_Q	406_S	1.073	1.00
410_L	414_A	1.072	1.00
393_K	396_K	1.069	1.00
168_G	258_I	1.064	1.00
334_K	337_L	1.064	1.00
148_E	152_W	1.063	1.00
163_S	167_V	1.063	1.00
143_V	304_F	1.061	1.00
90_Y	94_W	1.057	1.00
130_S	134_I	1.051	1.00
112_G	127_W	1.051	1.00
203_L	415_F	1.045	1.00
387_L	392_K	1.039	1.00
50_A	249_V	1.037	1.00
65_E	68_I	1.034	1.00
69_Q	393_K	1.032	1.00
414_A	418_I	1.022	1.00
440_L	444_Y	1.019	1.00
341_G	345_V	1.018	1.00
430_V	433_G	1.014	1.00
438_L	442_A	1.010	1.00
377_L	410_L	1.009	1.00
136_T	140_F	1.007	1.00
435_I	438_L	1.007	1.00
58_F	405_T	1.006	1.00
140_F	331_I	1.000	1.00
192_G	196_P	0.996	1.00
374_A	413_L	0.988	1.00
174_A	177_G	0.977	1.00
170_L	174_A	0.974	1.00
429_A	433_G	0.969	1.00
133_V	137_G	0.968	1.00
22_L	244_I	0.967	1.00
394_Q	398_K	0.966	1.00
134_I	296_L	0.966	1.00
140_F	327_T	0.961	1.00
158_I	247_F	0.959	1.00
418_I	422_Y	0.957	1.00
121_D	124_N	0.952	1.00
80_A	88_A	0.949	1.00
223_A	233_L	0.947	1.00
170_L	173_I	0.944	1.00
162_L	166_A	0.941	1.00
217_E	221_V	0.940	1.00
74_G	77_S	0.940	1.00
239_T	243_R	0.940	1.00
19_L	151_F	0.939	1.00
115_M	292_L	0.939	1.00
135_M	300_N	0.938	1.00
214_L	369_A	0.930	1.00
68_I	396_K	0.928	1.00
436_W	443_V	0.925	1.00
327_T	330_G	0.923	1.00
281_P	285_G	0.919	1.00
121_D	125_W	0.916	1.00
198_G	201_G	0.915	1.00
279_G	283_A	0.912	1.00
53_G	213_Y	0.911	1.00
46_L	256_M	0.907	1.00
153_F	297_S	0.907	1.00
195_F	202_V	0.907	1.00
172_I	176_V	0.906	1.00
409_S	413_L	0.901	1.00
391_E	394_Q	0.901	1.00
323_Y	334_K	0.897	1.00
440_L	443_V	0.897	1.00
81_R	316_Q	0.897	1.00
415_F	418_I	0.895	1.00
431_I	434_P	0.893	1.00
245_L	249_V	0.893	1.00
38_I	45_I	0.892	1.00
157_K	294_A	0.890	1.00
428_V	432_I	0.889	1.00
439_I	443_V	0.886	1.00
172_I	175_G	0.886	1.00
333_G	337_L	0.884	1.00
112_G	128_A	0.881	1.00
260_P	277_K	0.880	1.00
267_Q	270_P	0.878	1.00
66_M	380_Q	0.878	1.00
74_G	78_R	0.876	1.00
148_E	151_F	0.875	1.00
303_I	340_A	0.874	1.00
168_G	172_I	0.874	1.00
367_F	433_G	0.872	1.00
15_R	151_F	0.871	1.00
190_N	193_G	0.868	1.00
374_A	378_L	0.868	1.00
439_I	442_A	0.867	1.00
173_I	177_G	0.862	1.00
319_A	323_Y	0.862	1.00
123_P	126_I	0.861	1.00
127_W	130_S	0.860	1.00
164_M	275_F	0.859	1.00
11_G	144_K	0.857	1.00
429_A	432_I	0.855	1.00
106_A	362_T	0.854	1.00
204_L	208_M	0.850	1.00
428_V	433_G	0.850	1.00
433_G	437_F	0.849	1.00
8_L	225_E	0.849	1.00
165_I	254_V	0.848	1.00
16_H	148_E	0.848	1.00
258_I	274_T	0.846	1.00
57_F	61_R	0.846	1.00
50_A	54_L	0.845	1.00
381_I	406_S	0.844	1.00
428_V	431_I	0.843	1.00
94_W	319_A	0.838	1.00
106_A	211_F	0.837	1.00
96_Y	100_W	0.835	1.00
387_L	393_K	0.834	1.00
193_G	196_P	0.833	1.00
8_L	308_R	0.826	1.00
109_T	361_V	0.825	1.00
340_A	344_L	0.822	1.00
395_L	398_K	0.821	1.00
218_M	305_S	0.821	1.00
59_I	413_L	0.819	1.00
199_L	202_V	0.817	1.00
165_I	169_L	0.816	1.00
132_L	347_V	0.811	1.00
111_V	296_L	0.811	1.00
112_G	115_M	0.808	1.00
280_I	283_A	0.807	1.00
137_G	140_F	0.804	1.00
261_W	264_I	0.803	1.00
26_I	29_G	0.803	1.00
135_M	303_I	0.801	1.00
364_I	368_G	0.800	1.00
430_V	434_P	0.798	1.00
58_F	62_A	0.796	1.00
434_P	437_F	0.795	1.00
14_E	236_A	0.794	1.00
253_F	257_S	0.793	1.00
192_G	195_F	0.790	1.00
80_A	379_S	0.789	1.00
111_V	295_A	0.786	1.00
87_L	441_L	0.785	1.00
88_A	375_I	0.784	1.00
115_M	119_F	0.782	1.00
265_G	270_P	0.782	1.00
402_F	405_T	0.781	1.00
18_S	236_A	0.779	1.00
108_I	112_G	0.778	1.00
387_L	391_E	0.777	1.00
85_G	448_G	0.775	1.00
87_L	91_L	0.775	1.00
57_F	238_D	0.770	1.00
47_V	202_V	0.769	1.00
194_F	197_H	0.768	1.00
435_I	442_A	0.768	1.00
269_S	272_V	0.767	1.00
214_L	373_W	0.767	1.00
433_G	436_W	0.765	1.00
332_P	335_A	0.763	1.00
26_I	157_K	0.760	1.00
228_N	234_A	0.759	1.00
116_G	120_P	0.758	1.00
84_L	87_L	0.758	1.00
400_P	404_F	0.756	1.00
11_G	143_V	0.754	1.00
234_A	237_I	0.753	1.00
380_Q	384_R	0.753	1.00
69_Q	396_K	0.750	1.00
322_A	338_A	0.750	1.00
66_M	79_Y	0.749	1.00
61_R	405_T	0.747	1.00
46_L	50_A	0.742	1.00
195_F	198_G	0.740	1.00
169_L	250_G	0.739	1.00
58_F	409_S	0.734	1.00
381_I	403_P	0.729	1.00
417_V	420_M	0.728	1.00
15_R	148_E	0.727	1.00
139_N	336_V	0.726	1.00
101_V	342_A	0.724	1.00
129_L	348_L	0.723	1.00
275_F	278_V	0.723	1.00
47_V	51_A	0.722	1.00
141_L	145_A	0.720	1.00
270_P	275_F	0.720	1.00
432_I	435_I	0.719	1.00
147_G	151_F	0.718	1.00
103_T	107_E	0.713	1.00
381_I	385_K	0.710	1.00
11_G	15_R	0.709	1.00
328_K	333_G	0.709	1.00
308_R	311_F	0.707	1.00
43_P	256_M	0.707	1.00
25_A	240_V	0.706	1.00
436_W	439_I	0.704	1.00
282_S	285_G	0.704	1.00
307_G	335_A	0.702	1.00
83_Y	382_K	0.699	1.00
103_T	365_A	0.694	1.00
122_V	126_I	0.694	1.00
145_A	148_E	0.688	1.00
185_I	189_W	0.688	1.00
172_I	177_G	0.687	1.00
265_G	269_S	0.684	1.00
77_S	81_R	0.683	1.00
379_S	383_Y	0.683	1.00
56_M	216_I	0.682	1.00
442_A	445_Y	0.680	1.00
403_P	406_S	0.680	1.00
47_V	50_A	0.680	1.00
310_L	338_A	0.679	1.00
323_Y	335_A	0.679	1.00
140_F	329_G	0.678	1.00
303_I	307_G	0.678	1.00
250_G	254_V	0.676	1.00
314_A	323_Y	0.676	1.00
33_G	362_T	0.675	1.00
30_L	251_A	0.675	1.00
26_I	247_F	0.672	1.00
409_S	412_F	0.672	1.00
433_G	438_L	0.672	1.00
105_M	361_V	0.671	1.00
63_L	376_I	0.670	1.00
413_L	416_V	0.670	1.00
83_Y	383_Y	0.669	1.00
432_I	444_Y	0.669	1.00
135_M	296_L	0.668	1.00
23_G	154_A	0.667	1.00
203_L	419_L	0.665	1.00
73_A	311_F	0.665	1.00
24_A	301_S	0.665	1.00
102_V	364_I	0.659	1.00
341_G	344_L	0.659	1.00
103_T	106_A	0.658	1.00
224_G	311_F	0.657	1.00
24_A	302_G	0.657	1.00
243_R	247_F	0.656	1.00
437_F	441_L	0.656	1.00
139_N	304_F	0.653	1.00
416_V	420_M	0.653	1.00
60_M	216_I	0.651	1.00
45_I	252_L	0.651	1.00
140_F	336_V	0.650	1.00
8_L	11_G	0.648	1.00
431_I	436_W	0.646	1.00
406_S	410_L	0.645	1.00
367_F	417_V	0.645	1.00
185_I	257_S	0.645	1.00
84_L	379_S	0.644	1.00
266_S	270_P	0.642	1.00
387_L	395_L	0.638	1.00
142_A	145_A	0.637	1.00
30_L	33_G	0.636	1.00
233_L	237_I	0.636	1.00
201_G	204_L	0.635	1.00
239_T	242_W	0.634	1.00
77_S	89_G	0.633	1.00
171_M	174_A	0.632	1.00
428_V	444_Y	0.631	1.00
190_N	194_F	0.630	1.00
95_N	372_T	0.628	1.00
99_L	369_A	0.628	1.00
306_T	310_L	0.627	1.00
62_A	409_S	0.625	1.00
64_G	68_I	0.624	1.00
49_Y	212_A	0.623	1.00
67_A	233_L	0.622	1.00
22_L	154_A	0.622	1.00
61_R	400_P	0.620	1.00
432_I	436_W	0.620	1.00
443_V	449_F	0.619	1.00
230_Q	396_K	0.619	1.00
251_A	255_I	0.619	1.00
37_A	41_A	0.619	1.00
428_V	443_V	0.618	1.00
172_I	254_V	0.617	1.00
132_L	344_L	0.615	1.00
115_M	131_A	0.614	1.00
220_G	237_I	0.611	1.00
111_V	115_M	0.611	1.00
438_L	441_L	0.610	1.00
189_W	193_G	0.610	1.00
147_G	300_N	0.610	1.00
191_N	196_P	0.610	1.00
66_M	83_Y	0.609	1.00
34_S	252_L	0.609	1.00
418_I	421_A	0.608	1.00
225_E	326_L	0.608	1.00
156_I	290_V	0.607	1.00
266_S	269_S	0.606	1.00
243_R	246_I	0.605	1.00
214_L	217_E	0.605	1.00
368_G	372_T	0.604	1.00
77_S	93_G	0.603	1.00
131_A	299_C	0.600	1.00
76_F	217_E	0.600	1.00
432_I	438_L	0.600	1.00
384_R	402_F	0.599	1.00
435_I	440_L	0.598	1.00
27_G	248_Y	0.597	1.00
167_V	171_M	0.596	1.00
51_A	206_L	0.595	1.00
133_V	136_T	0.595	1.00
168_G	173_I	0.594	1.00
430_V	435_I	0.593	1.00
117_F	120_P	0.593	1.00
229_P	232_S	0.593	1.00
143_V	222_T	0.592	1.00
395_L	399_M	0.591	1.00
294_A	297_S	0.590	1.00
221_V	305_S	0.590	1.00
21_S	25_A	0.590	1.00
436_W	441_L	0.589	1.00
226_V	233_L	0.588	1.00
15_R	18_S	0.585	1.00
114_Y	291_V	0.585	1.00
134_I	138_V	0.580	1.00
445_Y	448_G	0.580	1.00
60_M	64_G	0.578	1.00
36_S	359_T	0.578	1.00
417_V	430_V	0.577	1.00
359_T	362_T	0.575	1.00
30_L	34_S	0.575	1.00
18_S	21_S	0.575	1.00
105_M	346_G	0.574	1.00
136_T	303_I	0.574	1.00
428_V	440_L	0.573	1.00
130_S	133_V	0.573	1.00
100_W	302_G	0.572	1.00
433_G	443_V	0.572	1.00
399_M	402_F	0.572	1.00
146_Y	304_F	0.570	1.00
67_A	220_G	0.568	1.00
46_L	249_V	0.568	1.00
156_I	160_A	0.568	1.00
265_G	268_G	0.567	1.00
443_V	448_G	0.565	1.00
154_A	157_K	0.565	1.00
391_E	396_K	0.563	1.00
275_F	283_A	0.563	1.00
75_S	220_G	0.562	1.00
326_L	329_G	0.561	1.00
429_A	436_W	0.561	1.00
110_A	114_Y	0.559	1.00
76_F	221_V	0.558	1.00
40_L	204_L	0.556	1.00
394_Q	397_Y	0.556	1.00
392_K	396_K	0.556	1.00
374_A	417_V	0.556	1.00
225_E	332_P	0.556	1.00
85_G	89_G	0.556	1.00
19_L	154_A	0.554	1.00
381_I	410_L	0.554	1.00
254_V	257_S	0.553	1.00
117_F	288_N	0.553	1.00
369_A	372_T	0.552	1.00
107_E	110_A	0.551	1.00
59_I	217_E	0.551	1.00
34_S	38_I	0.550	1.00
145_A	149_L	0.550	1.00
199_L	203_L	0.550	1.00
37_A	209_V	0.549	1.00
393_K	398_K	0.547	1.00
52_S	213_Y	0.546	1.00
114_Y	272_V	0.546	1.00
370_I	413_L	0.545	1.00
101_V	339_S	0.543	1.00
191_N	194_F	0.542	1.00
52_S	210_M	0.542	1.00
46_L	49_Y	0.541	1.00
151_F	155_L	0.541	1.00
243_R	250_G	0.540	1.00
10_R	227_K	0.540	1.00
411_A	414_A	0.540	1.00
322_A	326_L	0.540	1.00
118_W	288_N	0.539	1.00
433_G	440_L	0.538	1.00
383_Y	387_L	0.537	1.00
289_F	293_T	0.537	1.00
107_E	295_A	0.536	1.00
308_R	326_L	0.535	1.00
92_T	372_T	0.534	1.00
17_I	222_T	0.534	1.00
37_A	205_S	0.532	1.00
86_P	448_G	0.531	1.00
406_S	420_M	0.531	1.00
13_E	144_K	0.531	1.00
259_Y	263_E	0.531	1.00
229_P	233_L	0.530	1.00
80_A	89_G	0.528	1.00
310_L	314_A	0.528	1.00
31_F	157_K	0.528	1.00
165_I	251_A	0.527	1.00
345_V	348_L	0.527	1.00
34_S	37_A	0.527	1.00
431_I	441_L	0.524	1.00
107_E	299_C	0.523	1.00
95_N	371_W	0.523	1.00
402_F	407_Y	0.522	1.00
396_K	399_M	0.522	1.00
156_I	293_T	0.522	1.00
49_Y	252_L	0.522	1.00
40_L	43_P	0.521	1.00
391_E	397_Y	0.519	1.00
43_P	46_L	0.519	1.00
431_I	440_L	0.518	1.00
171_M	176_V	0.518	1.00
401_L	406_S	0.518	1.00
212_A	248_Y	0.517	1.00
69_Q	391_E	0.516	1.00
433_G	442_A	0.515	1.00
116_G	124_N	0.515	1.00
231_K	234_A	0.514	1.00
333_G	336_V	0.513	1.00
444_Y	448_G	0.513	1.00
193_G	197_H	0.513	1.00
150_E	297_S	0.513	1.00
118_W	289_F	0.513	1.00
299_C	302_G	0.513	1.00
31_F	161_I	0.513	1.00
433_G	447_K	0.513	1.00
413_L	417_V	0.512	1.00
107_E	112_G	0.512	1.00
435_I	446_G	0.512	1.00
36_S	39_Q	0.511	1.00
214_L	365_A	0.511	1.00
152_W	155_L	0.510	1.00
167_V	280_I	0.509	1.00
133_V	337_L	0.509	1.00
270_P	278_V	0.509	1.00
286_I	290_V	0.509	1.00
36_S	40_L	0.509	1.00
108_I	111_V	0.508	1.00
105_M	343_L	0.506	1.00
392_K	398_K	0.505	1.00
61_R	397_Y	0.504	1.00
399_M	405_T	0.503	1.00
27_G	157_K	0.502	1.00
419_L	423_S	0.502	1.00
437_F	440_L	0.502	1.00
105_M	108_I	0.502	1.00
437_F	444_Y	0.501	1.00
274_T	278_V	0.501	1.00
40_L	205_S	0.500	1.00
189_W	192_G	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.9006	100	0.287	Contact Map
4djkA	2	0.8855	100	0.358	Contact Map
3giaA	1	0.9179	100	0.359	Contact Map
3dh4A	3	0.9266	99	0.854	Contact Map
2jlnA	1	0.8963	98.9	0.859	Contact Map
2xq2A	2	0.9222	98.9	0.861	Contact Map
4wgvA	2	0.8035	98	0.892	Contact Map
2a65A	2	0.9201	97.7	0.9	Contact Map
4xp4A	1	0.9352	97.6	0.902	Contact Map
4us3A	1	0.8359	93.9	0.93	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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