GREMLIN Database
YJZC - Uncharacterized protein YjzC
UniProt: O34585 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 59 (57)
Sequences: 114 (63)
Seq/√Len: 8.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
24_E50_N3.1430.91
9_P46_T2.8470.86
20_V28_M2.3140.71
34_K56_K2.3090.71
20_V56_K2.1830.67
4_Q11_Q1.9440.57
26_G29_V1.9150.56
33_Q37_L1.8830.55
6_Q52_L1.8030.51
3_Q20_V1.6630.46
5_H55_Y1.5580.41
9_P52_L1.3310.32
3_Q6_Q1.3060.31
42_M45_E1.2940.31
9_P38_S1.2920.31
1_M24_E1.2770.30
35_V52_L1.2730.30
33_Q47_S1.2500.29
22_I30_K1.2370.29
4_Q35_V1.1960.28
20_V42_M1.1800.27
30_K52_L1.1220.25
3_Q55_Y1.0990.25
9_P42_M1.0850.24
37_L41_E1.0790.24
34_K52_L1.0420.23
36_H46_T1.0310.22
31_N45_E1.0190.22
37_L47_S1.0010.22
41_E52_L0.9960.21
30_K47_S0.9930.21
12_K41_E0.9870.21
36_H47_S0.9670.21
25_T29_V0.9630.21
29_V39_A0.9570.20
27_S46_T0.9450.20
16_N57_R0.9390.20
18_V36_H0.9280.20
28_M57_R0.9090.19
16_N26_G0.9010.19
3_Q57_R0.8950.19
13_A49_H0.8920.19
8_R52_L0.8540.18
13_A55_Y0.8500.18
25_T36_H0.8440.17
45_E57_R0.8370.17
31_N42_M0.8350.17
5_H20_V0.8320.17
47_S56_K0.7970.16
38_S45_E0.7890.16
18_V45_E0.7890.16
28_M54_T0.7880.16
41_E56_K0.7840.16
11_Q25_T0.7780.16
24_E39_A0.7270.15
20_V38_S0.7270.15
4_Q8_R0.7200.15
33_Q45_E0.7070.14
26_G39_A0.7070.14
7_F35_V0.7020.14
30_K38_S0.6930.14
25_T49_H0.6900.14
11_Q36_H0.6700.14
13_A45_E0.6500.13
6_Q26_G0.6310.13
22_I26_G0.6150.13
12_K16_N0.6110.13
18_V39_A0.5990.12
36_H45_E0.5830.12
8_R47_S0.5820.12
18_V38_S0.5780.12
33_Q49_H0.5760.12
6_Q54_T0.5630.12
9_P45_E0.5590.12
20_V35_V0.5540.11
13_A17_G0.5500.11
4_Q12_K0.5500.11
35_V46_T0.5470.11
12_K48_N0.5390.11
31_N49_H0.5370.11
27_S30_K0.5340.11
18_V34_K0.5330.11
11_Q49_H0.5190.11
8_R50_N0.5180.11
18_V57_R0.5040.11
10_G41_E0.5000.11
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4o5jA 1 0.4068 8.2 0.919 Contact Map
1bypA 1 0.7119 4.6 0.928 Contact Map
4umwA 1 0.8814 3.2 0.933 Contact Map
1m0dA 2 0.9322 3 0.934 Contact Map
4bbjA 1 0.8814 2.9 0.935 Contact Map
1hn0A 1 0.9661 2.9 0.935 Contact Map
4dp9X 1 0.7119 2.9 0.935 Contact Map
3t9gA 3 0.5424 2.8 0.935 Contact Map
3j08A 2 0.8814 2.6 0.936 Contact Map
4quvA 2 0.7288 2.4 0.937 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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