GREMLIN Database
YFKT - Putative spore germination protein YfkT
UniProt: O34573 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 358 (341)
Sequences: 22609 (14693)
Seq/√Len: 795.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
45_V217_A4.0671.00
294_D297_A3.6531.00
297_A300_T3.3301.00
5_S203_S2.6751.00
300_T303_G2.6201.00
10_L211_F2.5561.00
159_L226_S2.4961.00
287_S291_S2.4391.00
83_I289_L2.3751.00
245_M248_R2.3581.00
6_A211_F2.3521.00
295_P300_T2.3391.00
201_N284_Y2.3341.00
207_K211_F2.2991.00
9_G202_R2.2731.00
127_I308_V2.2501.00
5_S8_Q2.2101.00
235_L249_Q2.1891.00
292_K295_P2.1831.00
6_A10_L2.1691.00
72_S76_P2.1631.00
135_E139_R2.1591.00
128_C132_E2.1441.00
293_I297_A2.0801.00
295_P298_M2.0791.00
296_K300_T2.0741.00
232_G235_L2.0651.00
258_R262_I2.0561.00
164_E167_N1.9941.00
344_L348_S1.9631.00
200_S291_S1.9461.00
120_G312_W1.9131.00
71_L82_I1.8861.00
8_Q142_Q1.8801.00
163_I229_S1.8561.00
13_G212_A1.8541.00
10_L215_L1.8511.00
72_S79_G1.8431.00
146_F150_I1.8271.00
29_M37_A1.8051.00
46_V50_P1.7941.00
245_M249_Q1.7761.00
295_P299_Y1.7701.00
40_S181_S1.7621.00
293_I300_T1.7491.00
4_T8_Q1.7231.00
297_A301_P1.7171.00
294_D298_M1.7111.00
292_K302_T1.7091.00
294_D299_Y1.7021.00
52_L209_T1.6971.00
293_I298_M1.6971.00
335_S338_L1.6931.00
62_H73_D1.6671.00
105_I118_L1.6561.00
161_T164_E1.6541.00
44_G185_A1.6451.00
300_T304_M1.6411.00
299_Y302_T1.6401.00
8_Q138_T1.6291.00
294_D301_P1.6251.00
300_T306_S1.6231.00
57_R60_K1.6071.00
316_N319_Q1.6051.00
320_L323_F1.5981.00
299_Y303_G1.5821.00
131_R301_P1.5801.00
248_R260_D1.5721.00
165_L169_T1.5521.00
198_L280_Y1.5491.00
36_N178_Y1.5491.00
150_I154_F1.5381.00
98_I275_I1.5381.00
130_A276_A1.5241.00
162_Q165_L1.5091.00
101_F122_I1.5011.00
293_I296_K1.4931.00
52_L213_I1.4761.00
210_I214_L1.4641.00
14_A215_L1.4611.00
113_T117_V1.4571.00
75_S78_A1.4571.00
214_L218_L1.4571.00
163_I168_L1.4551.00
151_L266_F1.4531.00
98_I123_I1.4491.00
302_T306_S1.4461.00
319_Q322_D1.4451.00
53_W210_I1.4331.00
114_P117_V1.4301.00
165_L168_L1.4121.00
239_F245_M1.4091.00
294_D300_T1.4011.00
174_G177_P1.3901.00
161_T166_Q1.3881.00
6_A207_K1.3851.00
293_I299_Y1.3421.00
126_A275_I1.3411.00
312_W315_L1.3361.00
164_E168_L1.3361.00
59_M70_L1.3351.00
74_S78_A1.3341.00
248_R252_I1.3221.00
80_R84_L1.3141.00
120_G124_F1.3101.00
162_Q168_L1.3051.00
156_P222_V1.2971.00
342_I346_I1.2881.00
261_L265_A1.2881.00
241_D245_M1.2831.00
38_W225_F1.2821.00
315_L318_N1.2791.00
17_T216_G1.2741.00
164_E170_P1.2661.00
299_Y304_M1.2641.00
163_I167_N1.2631.00
167_N170_P1.2501.00
42_I221_A1.2331.00
313_F316_N1.2321.00
163_I166_Q1.2301.00
302_T305_F1.2271.00
166_Q169_T1.2231.00
161_T165_L1.2101.00
111_P114_P1.2011.00
140_M144_F1.1981.00
312_W316_N1.1981.00
144_F273_V1.1871.00
64_D69_E1.1861.00
57_R346_I1.1831.00
69_E73_D1.1831.00
101_F268_I1.1811.00
160_A226_S1.1771.00
292_K297_A1.1671.00
4_T9_G1.1571.00
7_Y11_F1.1541.00
346_I349_K1.1531.00
298_M303_G1.1531.00
65_K200_S1.1531.00
338_L346_I1.1381.00
326_I330_I1.1371.00
9_G208_Y1.1331.00
307_V310_G1.1291.00
164_E169_T1.1151.00
204_V207_K1.1141.00
225_F229_S1.1141.00
87_S286_L1.1141.00
305_F309_C1.1131.00
345_I349_K1.1091.00
294_D302_T1.1091.00
14_A216_G1.1081.00
298_M301_P1.1041.00
113_T116_A1.1031.00
77_I81_I1.1031.00
54_L342_I1.0861.00
12_F198_L1.0851.00
132_E297_A1.0831.00
338_L344_L1.0801.00
343_Y347_K1.0781.00
97_D274_K1.0721.00
337_L341_L1.0701.00
96_H187_G1.0671.00
127_I131_R1.0641.00
102_I118_L1.0641.00
248_R257_D1.0611.00
13_G195_L1.0591.00
112_R115_M1.0541.00
325_R328_P1.0541.00
180_Q184_Y1.0471.00
296_K299_Y1.0461.00
125_V272_M1.0451.00
315_L319_Q1.0451.00
55_M67_I1.0441.00
149_G153_L1.0431.00
338_L341_L1.0401.00
24_H100_F1.0371.00
295_P302_T1.0311.00
159_L230_V1.0301.00
139_R143_I1.0281.00
331_N335_S1.0221.00
314_F317_T1.0201.00
112_R116_A1.0181.00
313_F318_N1.0121.00
68_Y288_F1.0061.00
139_R142_Q1.0051.00
11_F142_Q1.0051.00
324_N327_K1.0031.00
303_G306_S1.0021.00
129_I140_M1.0001.00
141_A276_A0.9951.00
64_D73_D0.9941.00
154_F158_T0.9891.00
341_L346_I0.9871.00
301_P305_F0.9831.00
331_N338_L0.9831.00
155_L159_L0.9821.00
331_N334_I0.9811.00
298_M302_T0.9801.00
334_I338_L0.9791.00
121_V125_V0.9781.00
297_A303_G0.9771.00
37_A224_L0.9711.00
36_N172_F0.9701.00
66_N69_E0.9661.00
295_P301_P0.9591.00
126_A276_A0.9561.00
124_F128_C0.9511.00
341_L344_L0.9511.00
86_F90_F0.9451.00
49_I210_I0.9421.00
162_Q167_N0.9421.00
218_L222_V0.9341.00
134_K280_Y0.9251.00
7_Y139_R0.9241.00
162_Q166_Q0.9201.00
247_I252_I0.9141.00
102_I119_G0.9111.00
161_T167_N0.9101.00
297_A304_M0.9081.00
118_L121_V0.9081.00
239_F242_P0.9071.00
71_L74_S0.9021.00
74_S344_L0.9021.00
57_R61_K0.9021.00
156_P160_A0.9011.00
301_P304_M0.8991.00
131_R305_F0.8961.00
217_A221_A0.8941.00
116_A120_G0.8881.00
190_G334_I0.8871.00
229_S232_G0.8871.00
74_S343_Y0.8861.00
126_A279_L0.8851.00
292_K296_K0.8791.00
194_I281_I0.8781.00
329_I333_V0.8761.00
193_I197_L0.8731.00
6_A208_Y0.8721.00
330_I334_I0.8701.00
132_E136_T0.8681.00
197_L281_I0.8661.00
4_T138_T0.8631.00
175_L179_L0.8621.00
38_W228_I0.8621.00
8_Q139_R0.8611.00
16_Y277_G0.8611.00
15_L145_L0.8611.00
58_L70_L0.8591.00
247_I250_I0.8581.00
297_A302_T0.8571.00
71_L78_A0.8561.00
110_L113_T0.8521.00
156_P226_S0.8511.00
153_L157_F0.8491.00
257_D261_L0.8481.00
258_R261_L0.8461.00
49_I53_W0.8451.00
300_T305_F0.8411.00
128_C131_R0.8391.00
345_I348_S0.8381.00
101_F272_M0.8361.00
279_L283_V0.8351.00
246_V252_I0.8351.00
313_F317_T0.8311.00
78_A81_I0.8291.00
293_I302_T0.8271.00
48_V192_L0.8261.00
342_I345_I0.8231.00
286_L303_G0.8231.00
206_L209_T0.8191.00
50_P54_L0.8191.00
29_M33_A0.8191.00
251_R259_S0.8181.00
127_I304_M0.8141.00
33_A40_S0.8141.00
294_D304_M0.8141.00
339_P342_I0.8131.00
162_Q169_T0.8111.00
7_Y142_Q0.8091.00
295_P304_M0.8091.00
161_T168_L0.8081.00
314_F318_N0.8071.00
45_V189_M0.8041.00
226_S229_S0.8031.00
211_F214_L0.8021.00
166_Q170_P0.8001.00
43_L182_G0.8001.00
304_M307_V0.7971.00
30_I37_A0.7931.00
229_S233_P0.7901.00
230_V246_V0.7891.00
29_M185_A0.7861.00
16_Y278_S0.7861.00
343_Y346_I0.7851.00
283_V304_M0.7811.00
179_L183_Y0.7791.00
340_L344_L0.7781.00
320_L324_N0.7731.00
339_P343_Y0.7721.00
215_L219_L0.7691.00
325_R333_V0.7671.00
228_I232_G0.7671.00
318_N321_I0.7661.00
148_F270_V0.7661.00
312_W318_N0.7641.00
237_S240_F0.7641.00
211_F215_L0.7621.00
284_Y287_S0.7581.00
200_S287_S0.7561.00
327_K335_S0.7541.00
39_H178_Y0.7491.00
317_T320_L0.7481.00
292_K299_Y0.7401.00
122_I275_I0.7401.00
292_K300_T0.7391.00
177_P180_Q0.7391.00
223_M227_S0.7371.00
117_V121_V0.7361.00
74_S347_K0.7341.00
127_I279_L0.7311.00
75_S79_G0.7301.00
168_L229_S0.7301.00
334_I341_L0.7301.00
334_I337_L0.7301.00
165_L170_P0.7291.00
106_N115_M0.7291.00
172_F178_Y0.7271.00
68_Y72_S0.7261.00
336_L340_L0.7261.00
68_Y83_I0.7211.00
308_V311_F0.7211.00
328_P335_S0.7211.00
328_P331_N0.7201.00
136_T139_R0.7201.00
332_V335_S0.7181.00
149_G219_L0.7151.00
214_L217_A0.7141.00
126_A272_M0.7121.00
312_W317_T0.7111.00
190_G193_I0.7101.00
333_V338_L0.7091.00
42_I46_V0.7071.00
10_L208_Y0.7071.00
133_G136_T0.7001.00
107_I264_A0.6971.00
52_L56_H0.6951.00
99_R103_N0.6881.00
156_P223_M0.6851.00
28_L32_S0.6841.00
341_L345_I0.6841.00
303_G307_V0.6831.00
26_P29_M0.6831.00
38_W221_A0.6831.00
127_I305_F0.6821.00
26_P224_L0.6801.00
335_S341_L0.6791.00
330_I338_L0.6771.00
293_I303_G0.6751.00
165_L171_V0.6741.00
300_T308_V0.6721.00
316_N320_L0.6701.00
7_Y10_L0.6691.00
65_K287_S0.6661.00
292_K298_M0.6641.00
32_S180_Q0.6641.00
41_Y224_L0.6641.00
136_T140_M0.6641.00
232_G249_Q0.6621.00
130_A280_Y0.6611.00
53_W57_R0.6581.00
98_I102_I0.6571.00
79_G83_I0.6551.00
299_Y306_S0.6551.00
28_L31_E0.6551.00
97_D275_I0.6541.00
40_S178_Y0.6521.00
300_T310_G0.6491.00
138_T142_Q0.6491.00
13_G17_T0.6481.00
54_L339_P0.6471.00
252_I257_D0.6451.00
162_Q170_P0.6441.00
335_S339_P0.6421.00
66_N288_F0.6401.00
344_L347_K0.6381.00
19_A220_L0.6331.00
324_N338_L0.6311.00
296_K304_M0.6301.00
142_Q146_F0.6291.00
40_S182_G0.6291.00
94_N311_F0.6281.00
39_H43_L0.6261.00
77_I80_R0.6261.00
101_F271_I0.6261.00
22_L223_M0.6231.00
300_T307_V0.6221.00
131_R299_Y0.6191.00
22_L26_P0.6191.00
311_F315_L0.6181.00
141_A277_G0.6161.00
112_R117_V0.6161.00
304_M308_V0.6151.00
325_R329_I0.6121.00
35_Q233_P0.6101.00
338_L342_I0.6071.00
176_I180_Q0.6071.00
245_M252_I0.6041.00
39_H42_I0.6041.00
105_I268_I0.6041.00
41_Y188_T0.6031.00
145_L148_F0.6031.00
333_V337_L0.6001.00
87_S91_L0.5991.00
32_S184_Y0.5991.00
318_N322_D0.5991.00
310_G314_F0.5991.00
163_I169_T0.5981.00
330_I335_S0.5971.00
90_F278_S0.5931.00
10_L13_G0.5921.00
326_I331_N0.5921.00
223_M243_A0.5891.00
331_N341_L0.5891.00
326_I329_I0.5851.00
242_P245_M0.5851.00
329_I332_V0.5821.00
104_L267_W0.5811.00
93_I96_H0.5801.00
294_D303_G0.5791.00
20_V187_G0.5761.00
122_I126_A0.5761.00
319_Q323_F0.5751.00
15_L19_A0.5741.00
247_I251_R0.5701.00
20_V24_H0.5691.00
327_K330_I0.5681.00
36_N171_V0.5681.00
56_H206_L0.5671.00
161_T170_P0.5661.00
173_E176_I0.5641.00
70_L196_P0.5631.00
11_F145_L0.5631.00
72_S75_S0.5621.00
68_Y79_G0.5591.00
81_I85_L0.5581.00
320_L338_L0.5571.00
81_I84_L0.5571.00
296_K301_P0.5541.00
49_I214_L0.5541.00
164_E171_V0.5531.00
143_I146_F0.5531.00
14_A18_L0.5531.00
124_F308_V0.5531.00
38_W42_I0.5531.00
338_L348_S0.5511.00
335_S348_S0.5501.00
94_N275_I0.5501.00
56_H60_K0.5491.00
317_T323_F0.5491.00
335_S344_L0.5461.00
71_L75_S0.5461.00
282_V286_L0.5441.00
172_F175_L0.5441.00
33_A181_S0.5441.00
321_I325_R0.5441.00
335_S342_I0.5421.00
16_Y194_I0.5411.00
49_I213_I0.5411.00
41_Y187_G0.5401.00
165_L229_S0.5381.00
82_I340_L0.5371.00
19_A23_K0.5371.00
300_T311_F0.5371.00
241_D244_Y0.5361.00
105_I122_I0.5341.00
337_L340_L0.5341.00
137_L280_Y0.5321.00
13_G16_Y0.5301.00
10_L212_A0.5291.00
110_L114_P0.5281.00
202_R208_Y0.5271.00
99_R323_F0.5251.00
59_M196_P0.5251.00
307_V311_F0.5241.00
265_A269_P0.5241.00
119_G315_L0.5241.00
327_K337_L0.5231.00
68_Y285_G0.5231.00
314_F323_F0.5191.00
14_A145_L0.5181.00
292_K301_P0.5171.00
322_D325_R0.5171.00
178_Y182_G0.5171.00
26_P227_S0.5171.00
242_P252_I0.5161.00
100_F104_L0.5161.00
12_F15_L0.5161.00
262_I266_F0.5151.00
138_T276_A0.5151.00
92_L95_A0.5141.00
286_L290_H0.5121.00
97_D100_F0.5121.00
163_I171_V0.5111.00
142_Q145_L0.5061.00
196_P209_T0.5061.00
124_F312_W0.5051.00
163_I170_P0.5031.00
216_G220_L0.5031.00
168_L228_I0.5021.00
284_Y290_H0.5011.00
20_V271_I0.5011.00
91_L95_A0.5001.00
153_L156_P0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3l1lA 2 0.9665 100 0.34 Contact Map
3giaA 1 0.9804 100 0.393 Contact Map
4djkA 2 0.9525 100 0.438 Contact Map
4wgvA 2 0.9525 98.3 0.845 Contact Map
2jlnA 1 0.9553 98.2 0.85 Contact Map
3dh4A 3 0.9525 98.2 0.85 Contact Map
2xq2A 2 0.9497 98.1 0.856 Contact Map
4us3A 1 0.9609 96.1 0.894 Contact Map
4xp4A 1 0.9804 94.7 0.904 Contact Map
2a65A 2 0.9637 94.6 0.904 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0121 seconds.