YECA - BACSU - GREMLIN Contacts

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YECA - Uncharacterized amino acid permease YecA

UniProt:	O34560	Sequences: MLPELQRSITWIQGTALTIGAVLGCGILILPSVTADTAGPASLFVWVFMSFLSFFLVGTLARLVKIAPSAGGITAYVQLAFQKKAGAILGWIMLGSVPIGVPIIALTGAHYVSYITEAADWQITLIAGCMLAISILLHMRGIQLSANISTLVICVIVFLLVTSIAVSLPHVTIAEFKPFLPHGWSAAGSVSVMIFFSFVGWEMITPLAEEFHRPEKDVPLSLFLAASCVAGLYIMLSFVTVGTHSYGENGEIASLAMLISKGAGESGVYVTVCLALFITFATIHANIAGFSRMVYALAREGHIPVFFGKLSATKRTPIRVLTAMAAVFGLVLAAHGLFQIDLTTLLKGPSAAFIASYICTMAAALKLLGRRDIGWWMALGAFVACAVIYSFSGWALLYPAVLAAAGYFYMKTKGGHKKKLDHVL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	424 (399)
Sequences:	24441 (15762)
Seq/√Len:	789.1

ECOLI - POTE FRLA AROP YJEH ANSP PROY ADIC PLAP YIFK PUUP GABP LYSP YBAT ARCD MMUP CADB PHEP YGJI YCAM CYCA YJEM GADC TNAB TYRP MTR
BACSU - YECA YHDG YFNA YBEC ASPP YBXG STET AAPA YBGF YVBW YDGF YTNA GABP HUTM ROCC ARCD ROCE YCGH YDAO YNDE GERBB GERAB GERKB YFKT
HALSA - Q9HHU7 Q9HQB3 Q9HSL5
SULSO - Q97U05 Q97XM0 Q7LXI7 Q97X49 Q97WS3 Q97ZB5 Q97Z63 Q97VA6 Q97WD4 Q97Y76 Q97U33 Q97VA8 Q97VR4 Q97YN3 Q97YX9 Q97U39

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
135_I	325_A	4.239	1.00
306_F	319_R	4.207	1.00
50_S	230_A	3.051	1.00
309_K	319_R	2.939	1.00
358_I	382_F	2.908	1.00
216_K	220_L	2.840	1.00
10_T	212_H	2.802	1.00
311_S	314_K	2.745	1.00
211_F	217_D	2.645	1.00
213_R	216_K	2.570	1.00
401_V	405_A	2.543	1.00
311_S	318_I	2.497	1.00
90_G	297_L	2.476	1.00
74_T	300_E	2.473	1.00
406_G	410_M	2.467	1.00
298_A	308_G	2.449	1.00
128_G	329_G	2.443	1.00
167_S	239_V	2.441	1.00
306_F	309_K	2.414	1.00
15_T	224_L	2.322	1.00
397_L	401_V	2.294	1.00
165_A	169_P	2.272	1.00
11_W	224_L	2.272	1.00
62_R	368_L	2.260	1.00
78_Q	86_G	2.216	1.00
209_E	299_R	2.160	1.00
407_Y	411_K	2.159	1.00
210_E	292_R	2.130	1.00
361_M	381_A	2.103	1.00
295_Y	299_R	2.081	1.00
11_W	217_D	2.073	1.00
322_T	326_A	2.057	1.00
257_M	260_S	2.039	1.00
136_L	140_R	2.038	1.00
132_A	329_G	2.023	1.00
408_F	412_T	2.020	1.00
379_L	383_V	2.002	1.00
14_G	211_F	1.997	1.00
135_I	321_L	1.973	1.00
139_M	318_I	1.972	1.00
394_W	397_L	1.951	1.00
143_Q	147_N	1.945	1.00
128_G	332_L	1.932	1.00
11_W	15_T	1.925	1.00
154_C	158_F	1.915	1.00
220_L	224_L	1.905	1.00
81_F	366_K	1.894	1.00
10_T	13_Q	1.873	1.00
94_L	324_M	1.857	1.00
266_S	270_V	1.853	1.00
127_A	332_L	1.848	1.00
78_Q	83_K	1.834	1.00
51_F	55_F	1.831	1.00
397_L	400_A	1.813	1.00
248_E	261_K	1.799	1.00
406_G	409_Y	1.789	1.00
307_F	323_A	1.785	1.00
59_T	361_M	1.781	1.00
301_G	305_V	1.780	1.00
81_F	362_A	1.768	1.00
245_S	248_E	1.761	1.00
132_A	325_A	1.756	1.00
257_M	261_K	1.728	1.00
34_T	42_S	1.724	1.00
77_V	89_L	1.673	1.00
13_Q	150_T	1.660	1.00
131_L	328_F	1.651	1.00
376_W	380_G	1.634	1.00
383_V	387_V	1.633	1.00
213_R	217_D	1.630	1.00
45_V	190_V	1.606	1.00
122_Q	125_L	1.605	1.00
366_K	369_G	1.590	1.00
396_L	399_P	1.586	1.00
223_F	227_S	1.581	1.00
89_L	359_C	1.573	1.00
101_V	328_F	1.571	1.00
18_T	225_A	1.556	1.00
15_T	228_C	1.553	1.00
139_M	322_T	1.549	1.00
105_A	283_I	1.540	1.00
400_A	404_A	1.537	1.00
138_H	284_H	1.537	1.00
158_F	162_T	1.528	1.00
394_W	399_P	1.521	1.00
362_A	382_F	1.514	1.00
314_K	318_I	1.513	1.00
227_S	231_G	1.511	1.00
112_V	126_I	1.503	1.00
140_R	314_K	1.493	1.00
171_V	174_A	1.490	1.00
121_W	125_L	1.485	1.00
6_Q	315_R	1.474	1.00
295_Y	310_L	1.471	1.00
52_L	384_A	1.469	1.00
394_W	398_Y	1.469	1.00
41_A	187_A	1.465	1.00
374_G	378_A	1.457	1.00
395_A	399_P	1.439	1.00
135_I	322_T	1.434	1.00
294_V	320_V	1.427	1.00
159_L	274_L	1.423	1.00
319_R	323_A	1.415	1.00
82_Q	85_A	1.415	1.00
9_I	13_Q	1.415	1.00
305_V	308_G	1.412	1.00
362_A	366_K	1.412	1.00
290_F	324_M	1.400	1.00
57_V	226_A	1.399	1.00
207_L	288_A	1.398	1.00
396_L	402_L	1.395	1.00
311_S	316_T	1.389	1.00
396_L	401_V	1.388	1.00
105_A	131_L	1.376	1.00
387_V	391_F	1.373	1.00
51_F	380_G	1.366	1.00
168_L	239_V	1.363	1.00
77_V	359_C	1.362	1.00
49_M	194_I	1.352	1.00
108_G	130_M	1.346	1.00
128_G	132_A	1.345	1.00
309_K	318_I	1.344	1.00
305_V	309_K	1.333	1.00
108_G	276_L	1.331	1.00
409_Y	412_T	1.330	1.00
375_W	379_L	1.326	1.00
131_L	325_A	1.317	1.00
57_V	222_L	1.316	1.00
81_F	85_A	1.313	1.00
70_A	209_E	1.311	1.00
55_F	380_G	1.304	1.00
67_A	79_L	1.291	1.00
13_Q	146_A	1.290	1.00
213_R	220_L	1.289	1.00
260_S	268_V	1.288	1.00
269_Y	273_C	1.283	1.00
164_I	235_M	1.283	1.00
157_V	161_V	1.278	1.00
172_T	175_E	1.273	1.00
56_L	361_M	1.253	1.00
231_G	235_M	1.252	1.00
291_S	321_L	1.251	1.00
11_W	220_L	1.241	1.00
217_D	220_L	1.237	1.00
75_A	79_L	1.237	1.00
373_I	377_M	1.232	1.00
214_P	219_P	1.227	1.00
80_A	363_A	1.227	1.00
395_A	398_Y	1.226	1.00
376_W	379_L	1.218	1.00
58_G	223_F	1.209	1.00
163_S	167_S	1.208	1.00
9_I	14_G	1.198	1.00
43_L	238_F	1.196	1.00
12_I	16_A	1.195	1.00
171_V	242_G	1.193	1.00
394_W	403_A	1.192	1.00
386_A	390_S	1.191	1.00
124_T	128_G	1.188	1.00
396_L	403_A	1.188	1.00
22_V	229_V	1.179	1.00
62_R	65_K	1.176	1.00
167_S	243_T	1.176	1.00
399_P	403_A	1.171	1.00
134_S	283_I	1.171	1.00
395_A	402_L	1.167	1.00
59_T	378_A	1.163	1.00
371_R	374_G	1.161	1.00
41_A	180_L	1.159	1.00
397_L	403_A	1.151	1.00
260_S	265_E	1.151	1.00
94_L	294_V	1.150	1.00
253_A	257_M	1.149	1.00
9_I	146_A	1.141	1.00
104_I	282_T	1.141	1.00
319_R	322_T	1.132	1.00
29_I	107_T	1.122	1.00
87_A	91_W	1.119	1.00
69_S	75_A	1.118	1.00
81_F	84_K	1.117	1.00
370_R	373_I	1.117	1.00
60_L	73_I	1.111	1.00
358_I	386_A	1.111	1.00
212_H	217_D	1.108	1.00
8_S	212_H	1.107	1.00
394_W	400_A	1.105	1.00
408_F	411_K	1.102	1.00
394_W	402_L	1.093	1.00
137_L	148_I	1.091	1.00
365_L	379_L	1.089	1.00
394_W	401_V	1.088	1.00
398_Y	401_V	1.084	1.00
294_V	303_I	1.073	1.00
399_P	402_L	1.072	1.00
77_V	85_A	1.063	1.00
389_Y	392_S	1.062	1.00
64_V	76_Y	1.060	1.00
299_R	308_G	1.060	1.00
14_G	221_S	1.057	1.00
112_V	116_T	1.056	1.00
407_Y	410_M	1.055	1.00
326_A	330_L	1.053	1.00
19_I	228_C	1.053	1.00
35_A	42_S	1.053	1.00
109_A	126_I	1.050	1.00
263_A	267_G	1.049	1.00
401_V	404_A	1.043	1.00
18_T	204_I	1.040	1.00
162_T	166_V	1.040	1.00
129_C	133_I	1.034	1.00
47_V	234_I	1.031	1.00
148_I	152_V	1.031	1.00
17_L	207_L	1.027	1.00
19_I	229_V	1.027	1.00
125_L	129_C	1.026	1.00
370_R	375_W	1.017	1.00
135_I	139_M	1.012	1.00
395_A	400_A	1.011	1.00
69_S	79_L	1.004	1.00
371_R	375_W	1.004	1.00
132_A	136_L	1.003	1.00
264_G	267_G	0.997	1.00
147_N	151_L	0.992	1.00
396_L	400_A	0.991	1.00
402_L	405_A	0.989	1.00
149_S	284_H	0.989	1.00
361_M	382_F	0.986	1.00
397_L	402_L	0.981	1.00
369_G	375_W	0.978	1.00
309_K	312_A	0.976	1.00
310_L	315_R	0.974	1.00
161_V	165_A	0.969	1.00
245_S	261_K	0.967	1.00
407_Y	412_T	0.966	1.00
364_A	378_A	0.963	1.00
358_I	362_A	0.957	1.00
199_V	353_F	0.957	1.00
133_I	280_F	0.955	1.00
74_T	296_A	0.948	1.00
142_I	288_A	0.946	1.00
382_F	386_A	0.944	1.00
400_A	403_A	0.936	1.00
375_W	378_A	0.935	1.00
188_G	387_V	0.934	1.00
139_M	316_T	0.933	1.00
385_C	388_I	0.931	1.00
371_R	378_A	0.924	1.00
208_A	218_V	0.924	1.00
108_G	279_T	0.924	1.00
358_I	385_C	0.923	1.00
373_I	376_W	0.921	1.00
164_I	239_V	0.919	1.00
112_V	276_L	0.917	1.00
91_W	303_I	0.917	1.00
157_V	232_L	0.915	1.00
390_S	393_G	0.914	1.00
103_I	196_F	0.906	1.00
23_L	26_G	0.905	1.00
238_F	242_G	0.904	1.00
202_E	206_P	0.904	1.00
371_R	377_M	0.902	1.00
152_V	281_A	0.900	1.00
8_S	143_Q	0.898	1.00
126_I	129_C	0.897	1.00
164_I	168_L	0.897	1.00
224_L	228_C	0.896	1.00
381_A	384_A	0.891	1.00
230_A	234_I	0.880	1.00
364_A	368_L	0.879	1.00
243_T	258_L	0.879	1.00
171_V	175_E	0.876	1.00
109_A	127_A	0.876	1.00
16_A	150_T	0.875	1.00
189_S	193_M	0.869	1.00
398_Y	402_L	0.868	1.00
287_I	325_A	0.867	1.00
43_L	241_V	0.866	1.00
307_F	319_R	0.864	1.00
134_S	284_H	0.862	1.00
147_N	150_T	0.859	1.00
71_G	74_T	0.858	1.00
85_A	359_C	0.856	1.00
50_S	198_F	0.854	1.00
348_G	352_A	0.854	1.00
203_M	289_G	0.850	1.00
398_Y	403_A	0.849	1.00
78_Q	300_E	0.847	1.00
381_A	385_C	0.843	1.00
71_G	75_A	0.843	1.00
113_S	123_I	0.841	1.00
156_I	278_I	0.838	1.00
365_L	375_W	0.834	1.00
55_F	377_M	0.834	1.00
13_Q	147_N	0.829	1.00
163_S	259_I	0.824	1.00
325_A	329_G	0.823	1.00
103_I	346_L	0.822	1.00
387_V	390_S	0.822	1.00
388_I	392_S	0.818	1.00
54_F	58_G	0.816	1.00
175_E	178_P	0.814	1.00
406_G	412_T	0.810	1.00
12_I	150_T	0.807	1.00
318_I	322_T	0.799	1.00
44_F	187_A	0.794	1.00
124_T	332_L	0.793	1.00
265_E	269_Y	0.792	1.00
395_A	401_V	0.786	1.00
303_I	307_F	0.783	1.00
363_A	367_L	0.782	1.00
385_C	389_Y	0.782	1.00
365_L	369_G	0.777	1.00
54_F	223_F	0.773	1.00
136_L	139_M	0.772	1.00
140_R	144_L	0.768	1.00
168_L	235_M	0.767	1.00
131_L	332_L	0.763	1.00
312_A	318_I	0.763	1.00
406_G	411_K	0.763	1.00
180_L	187_A	0.759	1.00
254_S	259_I	0.757	1.00
176_F	242_G	0.755	1.00
55_F	59_T	0.752	1.00
47_V	51_F	0.751	1.00
63_L	364_A	0.750	1.00
138_H	321_L	0.745	1.00
11_W	221_S	0.744	1.00
139_M	311_S	0.743	1.00
109_A	123_I	0.743	1.00
134_S	287_I	0.742	1.00
172_T	176_F	0.738	1.00
166_V	170_H	0.736	1.00
98_P	327_V	0.732	1.00
12_I	147_N	0.728	1.00
77_V	363_A	0.726	1.00
24_G	28_L	0.726	1.00
219_P	222_L	0.725	1.00
372_D	376_W	0.724	1.00
388_I	391_F	0.723	1.00
15_T	221_S	0.722	1.00
180_L	184_W	0.721	1.00
373_I	378_A	0.718	1.00
378_A	385_C	0.718	1.00
27_I	236_L	0.715	1.00
84_K	88_I	0.713	1.00
74_T	78_Q	0.712	1.00
213_R	219_P	0.711	1.00
108_G	280_F	0.710	1.00
44_F	48_F	0.710	1.00
199_V	357_Y	0.709	1.00
81_F	363_A	0.707	1.00
63_L	76_Y	0.706	1.00
326_A	329_G	0.706	1.00
8_S	142_I	0.706	1.00
62_R	66_I	0.705	1.00
139_M	314_K	0.705	1.00
100_G	349_P	0.703	1.00
292_R	295_Y	0.700	1.00
164_I	236_L	0.699	1.00
182_H	185_S	0.698	1.00
298_A	307_F	0.697	1.00
173_I	176_F	0.694	1.00
146_A	150_T	0.694	1.00
399_P	405_A	0.693	1.00
291_S	320_V	0.693	1.00
106_L	345_L	0.691	1.00
341_D	344_T	0.690	1.00
259_I	264_G	0.688	1.00
70_A	295_Y	0.688	1.00
56_L	385_C	0.688	1.00
15_T	18_T	0.687	1.00
124_T	127_A	0.686	1.00
174_A	177_K	0.686	1.00
224_L	227_S	0.683	1.00
312_A	315_R	0.682	1.00
139_M	321_L	0.681	1.00
109_A	112_V	0.680	1.00
134_S	280_F	0.679	1.00
379_L	382_F	0.679	1.00
374_G	377_M	0.679	1.00
128_G	333_A	0.679	1.00
22_V	225_A	0.677	1.00
307_F	320_V	0.677	1.00
80_A	366_K	0.676	1.00
395_A	405_A	0.675	1.00
254_S	258_L	0.673	1.00
44_F	47_V	0.672	1.00
53_S	201_W	0.672	1.00
23_L	28_L	0.671	1.00
306_F	323_A	0.671	1.00
59_T	371_R	0.670	1.00
144_L	147_N	0.669	1.00
236_L	240_T	0.667	1.00
132_A	135_I	0.666	1.00
42_S	237_S	0.665	1.00
209_E	295_Y	0.664	1.00
403_A	406_G	0.663	1.00
33_V	343_T	0.662	1.00
20_G	153_I	0.660	1.00
34_T	38_A	0.658	1.00
384_A	388_I	0.658	1.00
93_M	97_V	0.657	1.00
112_V	130_M	0.654	1.00
74_T	90_G	0.653	1.00
186_A	189_S	0.653	1.00
287_I	291_S	0.651	1.00
138_H	288_A	0.651	1.00
368_L	375_W	0.651	1.00
23_L	156_I	0.650	1.00
55_F	381_A	0.649	1.00
253_A	256_A	0.649	1.00
61_A	65_K	0.641	1.00
183_G	186_A	0.641	1.00
31_P	237_S	0.640	1.00
43_L	234_I	0.638	1.00
99_I	348_G	0.638	1.00
228_C	232_L	0.637	1.00
375_W	392_S	0.636	1.00
48_F	191_S	0.634	1.00
294_V	323_A	0.633	1.00
235_M	239_V	0.633	1.00
64_V	218_V	0.632	1.00
155_V	274_L	0.631	1.00
63_L	80_A	0.630	1.00
60_L	360_T	0.627	1.00
383_V	386_A	0.627	1.00
100_G	103_I	0.626	1.00
171_V	176_F	0.625	1.00
114_Y	272_V	0.623	1.00
43_L	47_V	0.622	1.00
46_W	197_S	0.620	1.00
378_A	382_F	0.618	1.00
365_L	378_A	0.618	1.00
273_C	277_F	0.618	1.00
80_A	367_L	0.617	1.00
8_S	12_I	0.617	1.00
64_V	205_T	0.616	1.00
385_C	392_S	0.615	1.00
40_P	241_V	0.615	1.00
354_I	385_C	0.615	1.00
21_A	203_M	0.615	1.00
57_V	201_W	0.612	1.00
123_I	127_A	0.608	1.00
113_S	117_E	0.607	1.00
115_I	272_V	0.606	1.00
205_T	222_L	0.606	1.00
73_I	202_E	0.606	1.00
97_V	286_N	0.605	1.00
104_I	283_I	0.605	1.00
96_S	353_F	0.605	1.00
144_L	148_I	0.605	1.00
131_L	329_G	0.604	1.00
102_P	345_L	0.602	1.00
206_P	289_G	0.601	1.00
37_T	189_S	0.600	1.00
377_M	391_F	0.600	1.00
66_I	367_L	0.600	1.00
266_S	269_Y	0.599	1.00
184_W	187_A	0.597	1.00
188_G	391_F	0.596	1.00
18_T	22_V	0.596	1.00
135_I	287_I	0.593	1.00
311_S	315_R	0.593	1.00
378_A	393_G	0.593	1.00
92_I	355_A	0.593	1.00
259_I	267_G	0.592	1.00
92_I	356_S	0.591	1.00
102_P	331_V	0.587	1.00
98_P	324_M	0.587	1.00
290_F	294_V	0.587	1.00
278_I	281_A	0.586	1.00
57_V	61_A	0.586	1.00
292_R	310_L	0.586	1.00
158_F	161_V	0.586	1.00
228_C	231_G	0.585	1.00
317_P	320_V	0.583	1.00
21_A	286_N	0.583	1.00
374_G	379_L	0.582	1.00
130_M	283_I	0.582	1.00
141_G	144_L	0.582	1.00
146_A	284_H	0.581	1.00
397_L	405_A	0.581	1.00
343_T	346_L	0.581	1.00
378_A	392_S	0.580	1.00
236_L	255_L	0.579	1.00
218_V	222_L	0.579	1.00
21_A	285_A	0.578	1.00
150_T	154_C	0.578	1.00
74_T	86_G	0.578	1.00
384_A	387_V	0.577	1.00
104_I	107_T	0.576	1.00
142_I	207_L	0.576	1.00
155_V	159_L	0.575	1.00
82_Q	86_G	0.575	1.00
105_A	109_A	0.575	1.00
370_R	374_G	0.573	1.00
210_E	310_L	0.573	1.00
31_P	35_A	0.572	1.00
396_L	405_A	0.571	1.00
107_T	111_Y	0.571	1.00
239_V	242_G	0.569	1.00
405_A	408_F	0.568	1.00
216_K	219_P	0.568	1.00
306_F	310_L	0.567	1.00
210_E	317_P	0.566	1.00
115_I	273_C	0.566	1.00
395_A	403_A	0.565	1.00
34_T	190_V	0.565	1.00
166_V	264_G	0.564	1.00
111_Y	275_A	0.564	1.00
380_G	383_V	0.564	1.00
19_I	153_I	0.564	1.00
199_V	202_E	0.564	1.00
371_R	376_W	0.563	1.00
37_T	40_P	0.561	1.00
14_G	207_L	0.561	1.00
100_G	104_I	0.560	1.00
270_V	274_L	0.560	1.00
181_P	185_S	0.559	1.00
352_A	356_S	0.559	1.00
73_I	206_P	0.559	1.00
7_R	212_H	0.558	1.00
33_V	37_T	0.558	1.00
169_P	172_T	0.557	1.00
372_D	375_W	0.553	1.00
244_H	248_E	0.552	1.00
211_F	221_S	0.551	1.00
368_L	374_G	0.551	1.00
58_G	377_M	0.551	1.00
394_W	405_A	0.551	1.00
12_I	15_T	0.551	1.00
153_I	156_I	0.550	1.00
176_F	241_V	0.550	1.00
365_L	382_F	0.549	1.00
77_V	86_G	0.547	1.00
244_H	258_L	0.547	1.00
184_W	188_G	0.547	1.00
49_M	198_F	0.546	1.00
49_M	195_F	0.545	1.00
91_W	406_G	0.545	1.00
33_V	36_D	0.545	1.00
323_A	327_V	0.544	1.00
202_E	357_Y	0.542	1.00
104_I	279_T	0.541	1.00
211_F	218_V	0.541	1.00
399_P	404_A	0.541	1.00
204_I	218_V	0.541	1.00
23_L	232_L	0.540	1.00
403_A	410_M	0.539	1.00
248_E	251_E	0.538	1.00
195_F	350_S	0.537	1.00
30_L	346_L	0.537	1.00
23_L	30_L	0.535	1.00
67_A	80_A	0.535	1.00
166_V	263_A	0.533	1.00
382_F	385_C	0.532	1.00
330_L	333_A	0.531	1.00
400_A	405_A	0.531	1.00
110_H	123_I	0.530	1.00
133_I	137_L	0.530	1.00
396_L	404_A	0.529	1.00
214_P	217_D	0.525	1.00
389_Y	397_L	0.525	1.00
292_R	317_P	0.524	1.00
145_S	288_A	0.522	1.00
388_I	393_G	0.521	1.00
372_D	378_A	0.521	1.00
214_P	218_V	0.520	1.00
40_P	43_L	0.519	1.00
283_I	286_N	0.519	1.00
159_L	270_V	0.518	1.00
10_T	143_Q	0.518	1.00
45_V	48_F	0.517	1.00
381_A	392_S	0.516	1.00
38_A	45_V	0.515	1.00
318_I	321_L	0.515	1.00
351_A	389_Y	0.514	1.00
34_T	194_I	0.514	1.00
370_R	377_M	0.513	1.00
259_I	263_A	0.512	1.00
335_H	341_D	0.512	1.00
89_L	356_S	0.510	1.00
199_V	349_P	0.509	1.00
31_P	240_T	0.509	1.00
382_F	392_S	0.509	1.00
155_V	277_F	0.508	1.00
178_P	181_P	0.508	1.00
151_L	154_C	0.507	1.00
61_A	222_L	0.507	1.00
99_I	349_P	0.506	1.00
329_G	332_L	0.506	1.00
129_C	132_A	0.506	1.00
24_G	233_Y	0.505	1.00
56_L	202_E	0.504	1.00
322_T	325_A	0.504	1.00
151_L	155_V	0.503	1.00
149_S	281_A	0.502	1.00
27_I	31_P	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l1lA	2	0.9646	100	0.25	Contact Map
3giaA	1	0.9764	100	0.289	Contact Map
4djkA	2	0.9316	100	0.346	Contact Map
3dh4A	3	0.9481	99	0.845	Contact Map
2xq2A	2	0.9505	98.9	0.849	Contact Map
2jlnA	1	0.9292	98.6	0.864	Contact Map
4wgvA	2	0.8373	97.8	0.889	Contact Map
2a65A	2	0.9387	96.5	0.91	Contact Map
4xp4A	1	0.9505	95.1	0.919	Contact Map
4us3A	1	0.9033	92.9	0.927	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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