URHG2 - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

URHG2 - Unsaturated rhamnogalacturonyl hydrolase YteR

UniProt:	O34559	Sequences: MGSMDQSIAVKSPLTYAEALANTIMNTYTVEELPPANRWHYHQGVFLCGVLRLWEATGEKRYFEYAKAYADLLIDDNGNLLFRRDELDAIQAGLILFPLYEQTKDERYVKAAKRLRSLYGTLNRTSEGGFWHKDGYPYQMWLDGLYMGGPFALKYANLKQETELFDQVVLQESLMRKHTKDAKTGLFYHAWDEAKKMPWANEETGCSPEFWARSIGWYVMSLADMIEELPKKHPNRHVWKNTLQDMIKSICRYQDKETGLWYQIVDKGDRSDNWLESSGSCLYMYAIAKGINKGYLDRAYETTLLKAYQGLIQHKTETSEDGAFLVKDICVGTSAGFYDYYVSRERSTNDLHGAGAFILAMTELEPLFRSAGK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	373 (323)
Sequences:	1866 (1371)
Seq/√Len:	76.3

BACSU - URHG2 URHG1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
212_A	279_G	5.013	1.00
290_G	296_L	4.392	1.00
284_M	307_A	4.132	1.00
255_D	258_T	3.861	1.00
251_C	303_T	3.757	1.00
247_I	287_I	3.660	1.00
60_K	64_E	3.469	1.00
109_V	113_K	3.154	1.00
260_L	280_S	3.074	1.00
292_N	363_E	2.987	1.00
243_L	290_G	2.975	1.00
253_Y	265_V	2.816	1.00
291_I	304_L	2.770	1.00
339_D	343_S	2.727	1.00
219_V	286_A	2.717	1.00
258_T	275_L	2.671	1.00
64_E	68_A	2.558	1.00
219_V	247_I	2.496	1.00
236_R	240_K	2.441	1.00
188_Y	210_F	2.411	1.00
314_H	328_D	2.395	1.00
129_G	140_M	2.341	1.00
91_Q	94_L	2.279	1.00
101_E	158_L	2.267	1.00
308_Y	361_M	2.158	1.00
124_R	167_Q	2.089	1.00
181_D	184_T	2.056	1.00
254_Q	307_A	2.034	1.00
54_W	63_F	2.026	1.00
255_D	275_L	2.005	1.00
173_S	238_V	1.900	1.00
212_A	265_V	1.898	1.00
288_A	304_L	1.872	1.00
240_K	295_Y	1.868	1.00
255_D	262_Y	1.855	1.00
301_E	305_L	1.848	1.00
181_D	210_F	1.848	1.00
117_S	120_G	1.848	1.00
169_V	235_N	1.843	1.00
250_I	283_Y	1.838	1.00
267_K	272_D	1.835	1.00
219_V	246_M	1.835	1.00
260_L	310_G	1.798	1.00
185_G	249_S	1.783	1.00
49_G	358_I	1.773	1.00
227_E	293_K	1.771	1.00
309_Q	313_Q	1.752	1.00
251_C	299_A	1.751	1.00
248_K	299_A	1.747	1.00
298_R	301_E	1.742	1.00
281_C	311_L	1.742	1.00
259_G	306_K	1.736	1.00
231_K	236_R	1.727	1.00
156_A	165_F	1.714	1.00
244_Q	297_D	1.697	1.00
176_R	245_D	1.689	1.00
261_W	307_A	1.678	1.00
248_K	300_Y	1.675	1.00
55_E	102_Q	1.660	1.00
220_M	282_L	1.646	1.00
288_A	364_L	1.642	1.00
176_R	242_T	1.625	1.00
230_P	233_H	1.607	1.00
127_E	177_K	1.598	1.00
100_Y	109_V	1.585	0.99
67_K	105_D	1.544	0.99
67_K	71_D	1.518	0.99
330_C	333_T	1.511	0.99
162_T	166_D	1.506	0.99
240_K	244_Q	1.504	0.99
180_K	185_G	1.501	0.99
244_Q	248_K	1.500	0.99
169_V	229_L	1.494	0.99
329_I	353_G	1.493	0.99
64_E	67_K	1.477	0.99
222_L	239_W	1.466	0.99
166_D	233_H	1.461	0.99
129_G	174_L	1.455	0.99
25_M	28_Y	1.451	0.99
141_W	147_M	1.450	0.99
280_S	307_A	1.431	0.99
325_L	349_N	1.429	0.99
52_R	55_E	1.428	0.99
219_V	250_I	1.424	0.99
363_E	366_P	1.422	0.99
152_A	167_Q	1.414	0.99
180_K	245_D	1.413	0.99
338_Y	342_V	1.406	0.99
223_A	243_L	1.397	0.99
176_R	187_F	1.393	0.99
277_S	328_D	1.384	0.99
98_P	154_K	1.378	0.99
251_C	287_I	1.334	0.98
145_L	172_E	1.313	0.98
71_D	108_Y	1.310	0.98
54_W	57_T	1.307	0.98
45_V	282_L	1.290	0.98
291_I	302_T	1.281	0.98
127_E	178_H	1.279	0.98
215_I	246_M	1.277	0.98
249_S	252_R	1.274	0.98
153_L	228_E	1.268	0.97
51_L	66_A	1.264	0.97
229_L	233_H	1.257	0.97
118_L	122_L	1.255	0.97
220_M	285_Y	1.236	0.97
157_N	228_E	1.236	0.97
247_I	296_L	1.232	0.97
254_Q	310_G	1.229	0.97
87_L	148_G	1.228	0.97
277_S	315_K	1.227	0.97
181_D	188_Y	1.222	0.97
167_Q	170_L	1.216	0.97
110_K	114_R	1.213	0.97
302_T	305_L	1.208	0.97
25_M	29_T	1.199	0.96
247_I	251_C	1.196	0.96
87_L	122_L	1.194	0.96
169_V	239_W	1.187	0.96
230_P	236_R	1.182	0.96
332_G	335_A	1.172	0.96
170_L	173_S	1.169	0.96
262_Y	275_L	1.155	0.96
241_N	245_D	1.137	0.95
209_E	264_I	1.133	0.95
93_G	115_L	1.133	0.95
263_Q	333_T	1.132	0.95
157_N	165_F	1.127	0.95
238_V	241_N	1.122	0.95
151_F	155_Y	1.119	0.95
263_Q	330_C	1.119	0.95
305_L	309_Q	1.112	0.95
63_F	67_K	1.105	0.94
215_I	265_V	1.093	0.94
172_E	239_W	1.093	0.94
170_L	174_L	1.088	0.94
292_N	366_P	1.086	0.94
87_L	130_F	1.086	0.94
184_T	249_S	1.084	0.94
70_A	95_I	1.082	0.94
226_I	236_R	1.077	0.94
116_R	152_A	1.075	0.93
142_L	214_S	1.067	0.93
71_D	107_R	1.058	0.93
216_G	356_A	1.055	0.93
254_Q	259_G	1.055	0.93
331_V	345_E	1.048	0.93
267_K	338_Y	1.047	0.93
227_E	289_K	1.042	0.92
106_E	109_V	1.030	0.92
138_Y	194_A	1.028	0.92
173_S	242_T	1.025	0.92
254_Q	303_T	1.025	0.92
175_M	179_T	1.024	0.92
97_F	158_L	1.022	0.92
272_D	342_V	1.009	0.91
247_I	290_G	1.005	0.91
180_K	184_T	1.003	0.91
243_L	247_I	1.001	0.91
185_G	245_D	0.998	0.91
156_A	168_V	0.997	0.91
254_Q	280_S	0.996	0.91
49_G	355_G	0.989	0.90
262_Y	273_N	0.986	0.90
52_R	359_L	0.982	0.90
45_V	355_G	0.980	0.90
187_F	242_T	0.976	0.90
287_I	303_T	0.975	0.90
308_Y	364_L	0.956	0.89
247_I	300_Y	0.955	0.89
67_K	99_L	0.954	0.89
237_H	241_N	0.951	0.88
56_A	362_T	0.951	0.88
185_G	252_R	0.946	0.88
142_L	218_Y	0.944	0.88
249_S	253_Y	0.942	0.88
152_A	156_A	0.942	0.88
26_N	29_T	0.941	0.88
103_T	108_Y	0.939	0.88
260_L	275_L	0.938	0.88
154_K	228_E	0.936	0.88
232_K	236_R	0.930	0.87
260_L	314_H	0.929	0.87
254_Q	306_K	0.927	0.87
106_E	110_K	0.926	0.87
169_V	233_H	0.924	0.87
97_F	112_A	0.922	0.87
304_L	364_L	0.922	0.87
289_K	293_K	0.918	0.87
243_L	286_A	0.914	0.86
93_G	151_F	0.911	0.86
332_G	352_H	0.905	0.86
284_M	304_L	0.903	0.86
319_S	325_L	0.874	0.84
265_V	283_Y	0.873	0.84
132_H	139_Q	0.872	0.84
187_F	218_Y	0.872	0.84
296_L	300_Y	0.871	0.84
241_N	244_Q	0.868	0.83
260_L	315_K	0.868	0.83
112_A	119_Y	0.866	0.83
119_Y	167_Q	0.859	0.83
169_V	173_S	0.859	0.83
220_M	224_D	0.857	0.83
173_S	235_N	0.856	0.83
41_Y	352_H	0.851	0.82
271_S	274_W	0.851	0.82
116_R	164_L	0.851	0.82
112_A	151_F	0.845	0.82
235_N	238_V	0.838	0.81
90_I	115_L	0.838	0.81
100_Y	106_E	0.836	0.81
195_K	204_T	0.835	0.81
281_C	357_F	0.835	0.81
216_G	282_L	0.834	0.81
132_H	141_W	0.832	0.81
315_K	328_D	0.830	0.81
188_Y	208_P	0.830	0.81
113_K	117_S	0.825	0.80
261_W	287_I	0.823	0.80
311_L	315_K	0.822	0.80
94_L	154_K	0.822	0.80
226_I	240_K	0.820	0.80
166_D	235_N	0.819	0.80
88_D	175_M	0.816	0.79
60_K	63_F	0.816	0.79
48_C	52_R	0.815	0.79
277_S	311_L	0.815	0.79
176_R	238_V	0.807	0.79
331_V	334_S	0.805	0.79
100_Y	103_T	0.803	0.78
182_A	237_H	0.800	0.78
132_H	147_M	0.799	0.78
248_K	251_C	0.796	0.78
285_Y	359_L	0.794	0.78
209_E	267_K	0.791	0.77
109_V	159_K	0.789	0.77
172_E	222_L	0.787	0.77
105_D	108_Y	0.784	0.77
180_K	187_F	0.782	0.77
319_S	327_K	0.776	0.76
55_E	98_P	0.776	0.76
213_R	278_S	0.774	0.76
210_F	266_D	0.773	0.76
42_H	351_L	0.770	0.75
248_K	252_R	0.768	0.75
156_A	164_L	0.768	0.75
231_K	293_K	0.766	0.75
281_C	327_K	0.766	0.75
125_T	129_G	0.764	0.75
162_T	232_K	0.760	0.74
69_Y	73_L	0.755	0.74
250_I	287_I	0.750	0.73
328_D	346_R	0.748	0.73
163_E	166_D	0.742	0.73
303_T	306_K	0.741	0.73
149_G	172_E	0.739	0.72
100_Y	159_K	0.739	0.72
49_G	362_T	0.739	0.72
326_V	353_G	0.739	0.72
259_G	307_A	0.737	0.72
263_Q	352_H	0.735	0.72
104_K	313_Q	0.732	0.72
157_N	160_Q	0.732	0.72
116_R	130_F	0.730	0.71
140_M	174_L	0.730	0.71
85_D	122_L	0.727	0.71
305_L	364_L	0.726	0.71
41_Y	263_Q	0.722	0.71
243_L	296_L	0.722	0.71
140_M	175_M	0.721	0.71
152_A	172_E	0.721	0.71
166_D	169_V	0.715	0.70
167_Q	171_Q	0.713	0.70
278_S	329_I	0.710	0.69
154_K	158_L	0.708	0.69
100_Y	104_K	0.704	0.69
116_R	161_E	0.700	0.68
41_Y	350_D	0.699	0.68
52_R	366_P	0.699	0.68
110_K	113_K	0.699	0.68
125_T	193_E	0.699	0.68
43_Q	351_L	0.694	0.68
90_I	118_L	0.694	0.68
179_T	214_S	0.691	0.67
103_T	107_R	0.690	0.67
260_L	277_S	0.690	0.67
335_A	340_Y	0.688	0.67
172_E	225_M	0.687	0.67
57_T	62_Y	0.687	0.67
213_R	352_H	0.686	0.67
209_E	338_Y	0.686	0.67
156_A	160_Q	0.686	0.67
290_G	294_G	0.682	0.66
150_P	225_M	0.682	0.66
179_T	206_C	0.679	0.66
291_I	296_L	0.679	0.66
254_Q	261_W	0.679	0.66
328_D	334_S	0.678	0.66
284_M	311_L	0.677	0.66
120_G	123_N	0.677	0.66
70_A	99_L	0.675	0.65
152_A	168_V	0.674	0.65
290_G	300_Y	0.673	0.65
101_E	154_K	0.673	0.65
267_K	342_V	0.671	0.65
156_A	162_T	0.670	0.65
188_Y	206_C	0.669	0.65
277_S	314_H	0.663	0.64
113_K	155_Y	0.660	0.64
35_P	281_C	0.659	0.64
100_Y	105_D	0.659	0.64
51_L	95_I	0.658	0.63
148_G	165_F	0.657	0.63
242_T	245_D	0.657	0.63
116_R	120_G	0.655	0.63
291_I	297_D	0.655	0.63
211_W	217_W	0.655	0.63
124_R	128_G	0.654	0.63
56_A	365_E	0.653	0.63
336_G	340_Y	0.653	0.63
262_Y	272_D	0.652	0.63
353_G	356_A	0.651	0.63
122_L	130_F	0.651	0.63
46_F	50_V	0.650	0.63
240_K	243_L	0.650	0.63
146_Y	224_D	0.649	0.62
53_L	62_Y	0.648	0.62
225_M	239_W	0.647	0.62
219_V	243_L	0.646	0.62
26_N	321_D	0.645	0.62
330_C	341_Y	0.645	0.62
145_L	239_W	0.643	0.62
86_E	89_A	0.641	0.61
67_K	108_Y	0.639	0.61
54_W	102_Q	0.638	0.61
87_L	144_G	0.637	0.61
297_D	303_T	0.636	0.61
164_L	168_V	0.635	0.61
261_W	283_Y	0.630	0.60
153_L	225_M	0.629	0.60
98_P	101_E	0.629	0.60
284_M	360_A	0.629	0.60
97_F	154_K	0.627	0.60
298_R	302_T	0.624	0.59
277_S	326_V	0.624	0.59
361_M	365_E	0.622	0.59
300_Y	303_T	0.621	0.59
116_R	155_Y	0.619	0.59
297_D	300_Y	0.618	0.59
143_D	217_W	0.618	0.59
161_E	164_L	0.617	0.59
152_A	164_L	0.616	0.58
77_N	80_L	0.616	0.58
182_A	241_N	0.615	0.58
262_Y	271_S	0.613	0.58
97_F	101_E	0.613	0.58
61_R	113_K	0.609	0.58
266_D	271_S	0.608	0.57
328_D	331_V	0.607	0.57
93_G	112_A	0.607	0.57
123_N	141_W	0.606	0.57
238_V	242_T	0.606	0.57
264_I	338_Y	0.599	0.56
189_H	289_K	0.599	0.56
76_D	301_E	0.597	0.56
330_C	335_A	0.597	0.56
145_L	171_Q	0.595	0.56
146_Y	155_Y	0.595	0.56
311_L	357_F	0.594	0.56
358_I	362_T	0.593	0.56
125_T	132_H	0.592	0.55
67_K	103_T	0.591	0.55
264_I	335_A	0.590	0.55
119_Y	123_N	0.588	0.55
48_C	146_Y	0.588	0.55
63_F	102_Q	0.585	0.55
62_Y	188_Y	0.583	0.54
126_S	196_K	0.581	0.54
329_I	332_G	0.581	0.54
224_D	289_K	0.575	0.53
70_A	92_A	0.574	0.53
247_I	286_A	0.574	0.53
229_L	360_A	0.573	0.53
309_Q	320_E	0.570	0.53
299_A	302_T	0.570	0.53
234_P	237_H	0.570	0.53
337_F	340_Y	0.569	0.53
40_H	43_Q	0.568	0.52
61_R	306_K	0.567	0.52
224_D	279_G	0.567	0.52
34_P	37_N	0.566	0.52
57_T	365_E	0.566	0.52
131_W	144_G	0.566	0.52
184_T	210_F	0.564	0.52
155_Y	159_K	0.563	0.52
326_V	330_C	0.561	0.52
219_V	283_Y	0.560	0.51
308_Y	312_I	0.559	0.51
146_Y	359_L	0.559	0.51
337_F	358_I	0.559	0.51
326_V	329_I	0.558	0.51
263_Q	344_R	0.557	0.51
46_F	69_Y	0.555	0.51
129_G	132_H	0.554	0.51
237_H	240_K	0.554	0.51
66_A	98_P	0.554	0.51
113_K	161_E	0.552	0.50
71_D	74_I	0.552	0.50
226_I	230_P	0.551	0.50
41_Y	330_C	0.551	0.50
42_H	352_H	0.550	0.50
250_I	265_V	0.550	0.50
260_L	311_L	0.550	0.50
88_D	144_G	0.550	0.50
104_K	108_Y	0.550	0.50
218_Y	242_T	0.549	0.50
287_I	291_I	0.549	0.50
153_L	157_N	0.547	0.50
153_L	168_V	0.546	0.50
220_M	223_A	0.545	0.49
280_S	311_L	0.543	0.49
176_R	180_K	0.540	0.49
149_G	168_V	0.539	0.49
276_E	353_G	0.539	0.49
246_M	286_A	0.537	0.48
310_G	315_K	0.537	0.48
151_F	171_Q	0.536	0.48
167_Q	172_E	0.536	0.48
291_I	301_E	0.536	0.48
124_R	171_Q	0.534	0.48
66_A	99_L	0.534	0.48
330_C	350_D	0.533	0.48
309_Q	364_L	0.532	0.48
170_L	235_N	0.532	0.48
112_A	155_Y	0.531	0.48
303_T	307_A	0.531	0.48
329_I	333_T	0.530	0.48
41_Y	144_G	0.529	0.47
42_H	95_I	0.529	0.47
61_R	298_R	0.528	0.47
130_F	152_A	0.528	0.47
154_K	225_M	0.527	0.47
260_L	313_Q	0.526	0.47
88_D	143_D	0.526	0.47
192_D	204_T	0.526	0.47
173_S	237_H	0.525	0.47
218_Y	222_L	0.525	0.47
350_D	355_G	0.523	0.47
261_W	303_T	0.523	0.47
42_H	84_R	0.522	0.47
51_L	98_P	0.522	0.47
298_R	313_Q	0.521	0.46
240_K	293_K	0.521	0.46
60_K	241_N	0.520	0.46
177_K	238_V	0.520	0.46
128_G	140_M	0.520	0.46
195_K	205_G	0.520	0.46
315_K	361_M	0.519	0.46
327_K	348_T	0.519	0.46
55_E	298_R	0.519	0.46
185_G	248_K	0.518	0.46
333_T	344_R	0.517	0.46
226_I	229_L	0.515	0.46
115_L	118_L	0.515	0.46
99_L	108_Y	0.515	0.46
88_D	217_W	0.514	0.46
206_C	210_F	0.513	0.45
149_G	179_T	0.513	0.45
329_I	334_S	0.511	0.45
160_Q	164_L	0.509	0.45
226_I	295_Y	0.509	0.45
267_K	271_S	0.507	0.45
133_K	136_Y	0.507	0.45
312_I	320_E	0.505	0.44
326_V	333_T	0.504	0.44
139_Q	147_M	0.503	0.44
113_K	159_K	0.503	0.44
205_G	267_K	0.503	0.44
187_F	215_I	0.503	0.44
137_P	194_A	0.503	0.44
55_E	227_E	0.501	0.44
139_Q	192_D	0.501	0.44
332_G	350_D	0.500	0.44

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1nc5A	1	0.9732	100	0.274	Contact Map
4wu0A	1	0.9383	100	0.304	Contact Map
3k11A	3	0.9544	100	0.361	Contact Map
4ce7A	3	0.9088	100	0.378	Contact Map
4xuvA	2	0.8713	100	0.387	Contact Map
3pmmA	1	0.933	100	0.421	Contact Map
4q88A	1	0.8928	100	0.422	Contact Map
3wiwA	1	0.9088	100	0.565	Contact Map
2ahfA	1	0.9249	100	0.609	Contact Map
2zzrA	1	0.9303	100	0.61	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0104 seconds.