PTWCB - BACSU - GREMLIN Contacts

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PTWCB - PTS system N-acetylglucosamine-specific EIICB component

UniProt:	O34521	Sequences: MLSFLQKLGKSFMLPIAVLPAVGIILALGREDVFNIPFVYQAGTAVFDHLPLIFAIGIAIGISKDSNGAAGLSGAISYLMLDAATKTIDKTNNMAVFGGIIAGLIAGYTYNRFKDTKLPEYLGFFSGRRLVPILTAIITIILAGIFGVVWPPIQSCINSFGEWMLGLGGIGAGIFGLFNRLLIPLGLHHVLNNIFWFQFGEYNGVTGDLARFFAKDPTAGTYMTGFFPIMMFGLPAACLAMVVTAKPSKRKATAGMMIGFALTAFITGITEPIEFAFMFLSPLLYAVHAVLTGLSLFIVNWLGIRSGFSFSAGAIDYVLSYGIAEKPLLLLLVGICYAAVYFIVFYVLIKALNLKTPGREDDDVDEVLDENTVQDVNENIMLKGLGGKENLQTIDHCATRLRLTVKDTALVDEALLKKAGAKGVVKSGGQSVQVIIGPNVEFAAEELRAAVK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	452 (409)
Sequences:	2831 (1603)
Seq/√Len:	79.3

ECOLI - PTW3C PTGCB PTOCB PTXC PTIBC PTTBC PTV3B PTYBC
BACSU - PTWCB PTW3C PTG3C PTOCB PTSBC SACX PTTBC PTV3B PTXBC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
243_V	346_Y	5.330	1.00
236_A	338_A	5.214	1.00
243_V	342_F	4.700	1.00
346_Y	350_K	4.666	1.00
331_L	335_I	3.817	1.00
392_Q	406_K	3.709	1.00
56_I	75_A	3.686	1.00
44_T	48_D	3.367	1.00
23_G	309_S	3.310	1.00
244_T	350_K	3.226	1.00
77_S	135_T	3.170	1.00
355_K	361_D	3.169	1.00
249_K	252_A	3.122	1.00
238_C	273_I	3.064	1.00
291_L	344_V	3.021	1.00
249_K	362_D	2.927	1.00
286_A	290_V	2.854	1.00
407_D	410_L	2.829	1.00
246_K	361_D	2.798	1.00
412_D	415_L	2.702	1.00
335_I	339_A	2.593	1.00
241_M	257_M	2.543	1.00
244_T	346_Y	2.543	1.00
287_V	291_L	2.449	1.00
415_L	418_K	2.434	1.00
232_F	334_G	2.425	1.00
134_L	138_I	2.409	1.00
116_T	130_L	2.352	1.00
384_G	415_L	2.333	1.00
348_L	352_L	2.300	1.00
177_L	293_G	2.282	1.00
231_M	265_F	2.220	1.00
106_A	135_T	2.204	1.00
176_G	296_L	2.202	1.00
302_L	333_V	2.184	1.00
179_N	226_F	2.149	1.00
342_F	346_Y	2.120	1.00
287_V	344_V	2.098	1.00
105_I	142_L	2.093	1.00
299_V	333_V	2.066	1.00
297_F	301_W	2.056	1.00
382_L	394_I	2.021	1.00
283_L	352_L	2.002	1.00
11_S	62_I	1.995	1.00
287_V	348_L	1.974	1.00
242_V	254_A	1.973	1.00
116_T	126_S	1.969	1.00
104_L	108_Y	1.959	1.00
393_T	404_T	1.946	1.00
405_V	408_T	1.943	1.00
102_A	139_T	1.939	1.00
317_Y	321_Y	1.927	1.00
303_G	326_K	1.920	1.00
209_L	223_M	1.912	1.00
344_V	348_L	1.881	1.00
405_V	411_V	1.874	1.00
30_R	40_Y	1.854	1.00
339_A	343_I	1.829	1.00
288_H	341_Y	1.786	1.00
177_L	286_A	1.776	1.00
243_V	350_K	1.759	1.00
413_E	417_K	1.723	1.00
234_L	237_A	1.685	1.00
314_A	318_V	1.669	1.00
343_I	346_Y	1.663	1.00
177_L	181_L	1.663	1.00
342_F	350_K	1.657	1.00
21_A	136_A	1.656	1.00
211_R	216_D	1.653	1.00
10_K	395_D	1.637	1.00
389_E	410_L	1.631	1.00
345_F	349_I	1.623	1.00
31_E	35_N	1.623	1.00
332_L	336_C	1.590	1.00
385_L	403_L	1.586	1.00
178_F	191_L	1.585	1.00
177_L	289_A	1.583	1.00
240_A	342_F	1.582	1.00
392_Q	404_T	1.566	1.00
347_V	351_A	1.563	1.00
207_G	211_R	1.555	0.99
324_A	327_P	1.548	0.99
342_F	345_F	1.545	0.99
144_G	148_V	1.539	0.99
103_G	143_A	1.516	0.99
239_L	243_V	1.513	0.99
254_A	258_I	1.501	0.99
329_L	332_L	1.501	0.99
173_G	297_F	1.488	0.99
365_D	368_L	1.486	0.99
169_G	301_W	1.460	0.99
5_L	8_L	1.456	0.99
13_M	189_H	1.453	0.99
328_L	332_L	1.452	0.99
117_K	120_E	1.451	0.99
137_I	141_I	1.440	0.99
380_I	415_L	1.438	0.99
176_G	292_T	1.432	0.99
299_V	304_I	1.430	0.99
105_I	138_I	1.428	0.99
211_R	217_P	1.417	0.99
211_R	215_K	1.414	0.99
373_V	376_V	1.408	0.99
29_G	43_G	1.402	0.99
50_L	96_V	1.400	0.99
198_Q	201_E	1.397	0.99
55_A	69_A	1.394	0.99
228_P	295_S	1.394	0.99
238_C	257_M	1.380	0.99
251_K	254_A	1.370	0.99
341_Y	345_F	1.364	0.99
343_I	347_V	1.348	0.98
340_V	344_V	1.325	0.98
229_I	292_T	1.320	0.98
291_L	340_V	1.319	0.98
123_G	269_I	1.311	0.98
383_K	415_L	1.308	0.98
75_A	79_L	1.301	0.98
335_I	338_A	1.295	0.98
321_Y	327_P	1.293	0.98
298_I	301_W	1.292	0.98
52_L	75_A	1.289	0.98
6_Q	61_G	1.280	0.98
355_K	360_E	1.277	0.98
256_M	260_F	1.269	0.98
346_Y	349_I	1.260	0.98
304_I	329_L	1.258	0.98
242_V	250_R	1.240	0.97
245_A	253_T	1.233	0.97
105_I	108_Y	1.231	0.97
247_P	250_R	1.224	0.97
60_I	71_G	1.219	0.97
298_I	302_L	1.218	0.97
230_M	264_A	1.217	0.97
241_M	253_T	1.215	0.97
26_L	44_T	1.210	0.97
181_L	289_A	1.209	0.97
177_L	290_V	1.202	0.97
278_M	285_Y	1.202	0.97
241_M	244_T	1.197	0.97
109_T	134_L	1.193	0.97
208_D	223_M	1.178	0.96
62_I	104_L	1.172	0.96
356_T	359_R	1.170	0.96
258_I	261_A	1.169	0.96
394_I	403_L	1.166	0.96
333_V	337_Y	1.161	0.96
294_L	337_Y	1.156	0.96
175_F	224_T	1.152	0.96
246_K	360_E	1.140	0.96
236_A	339_A	1.135	0.96
172_A	300_N	1.133	0.96
242_V	258_I	1.131	0.96
77_S	102_A	1.127	0.95
109_T	138_I	1.125	0.95
384_G	396_H	1.125	0.95
208_D	220_G	1.123	0.95
414_A	418_K	1.120	0.95
173_G	293_G	1.120	0.95
163_W	167_L	1.120	0.95
348_L	354_L	1.119	0.95
202_Y	211_R	1.108	0.95
208_D	211_R	1.106	0.95
102_A	142_L	1.097	0.95
169_G	297_F	1.096	0.95
156_C	160_F	1.084	0.94
242_V	257_M	1.083	0.94
173_G	177_L	1.082	0.94
333_V	338_A	1.081	0.94
274_E	285_Y	1.075	0.94
209_L	213_F	1.072	0.94
113_F	134_L	1.069	0.94
267_T	313_G	1.067	0.94
339_A	342_F	1.067	0.94
274_E	288_H	1.065	0.94
130_L	134_L	1.055	0.94
379_N	383_K	1.053	0.93
376_V	379_N	1.053	0.93
347_V	352_L	1.051	0.93
389_E	406_K	1.050	0.93
86_K	89_D	1.048	0.93
84_A	143_A	1.048	0.93
134_L	137_I	1.040	0.93
229_I	233_G	1.036	0.93
349_I	359_R	1.032	0.93
109_T	113_F	1.031	0.93
150_W	154_Q	1.029	0.93
349_I	356_T	1.026	0.93
243_V	250_R	1.024	0.92
25_I	43_G	1.020	0.92
374_Q	377_N	1.016	0.92
218_T	221_T	1.006	0.92
305_R	325_E	1.002	0.92
253_T	257_M	0.998	0.91
155_S	159_S	0.995	0.91
295_S	337_Y	0.991	0.91
14_L	60_I	0.991	0.91
114_K	134_L	0.986	0.91
77_S	139_T	0.985	0.91
381_M	416_L	0.983	0.91
105_I	139_T	0.981	0.91
334_G	338_A	0.980	0.91
249_K	360_E	0.979	0.91
65_D	115_D	0.976	0.91
198_Q	221_T	0.971	0.90
405_V	413_E	0.967	0.90
22_V	50_L	0.963	0.90
298_I	337_Y	0.959	0.90
93_N	96_V	0.958	0.90
119_P	122_L	0.954	0.90
49_H	79_L	0.952	0.89
337_Y	345_F	0.951	0.89
406_K	410_L	0.948	0.89
347_V	354_L	0.945	0.89
234_L	273_I	0.943	0.89
56_I	70_A	0.941	0.89
283_L	286_A	0.940	0.89
364_V	367_V	0.939	0.89
302_L	329_L	0.938	0.89
156_C	159_S	0.932	0.88
237_A	241_M	0.924	0.88
102_A	106_A	0.924	0.88
96_V	99_G	0.921	0.88
260_F	264_A	0.919	0.88
234_L	278_M	0.918	0.88
317_Y	332_L	0.917	0.88
196_W	311_S	0.917	0.88
384_G	416_L	0.914	0.87
210_A	213_F	0.914	0.87
208_D	213_F	0.912	0.87
226_F	308_F	0.912	0.87
334_G	341_Y	0.910	0.87
52_L	74_G	0.909	0.87
380_I	418_K	0.904	0.87
221_T	300_N	0.904	0.87
236_A	240_A	0.898	0.87
172_A	221_T	0.897	0.86
116_T	134_L	0.897	0.86
152_P	156_C	0.893	0.86
59_A	74_G	0.890	0.86
391_L	394_I	0.888	0.86
153_I	156_C	0.886	0.86
141_I	145_I	0.885	0.86
65_D	110_Y	0.885	0.86
180_R	274_E	0.880	0.85
26_L	47_F	0.875	0.85
269_I	398_A	0.872	0.85
337_Y	341_Y	0.871	0.85
377_N	380_I	0.870	0.85
249_K	363_D	0.869	0.85
338_A	341_Y	0.866	0.84
371_N	374_Q	0.862	0.84
56_I	66_S	0.857	0.84
23_G	263_T	0.854	0.84
12_F	128_R	0.850	0.83
4_F	8_L	0.849	0.83
332_L	335_I	0.848	0.83
129_R	132_P	0.848	0.83
118_L	130_L	0.845	0.83
380_I	383_K	0.837	0.82
197_F	209_L	0.836	0.82
291_L	341_Y	0.835	0.82
172_A	297_F	0.834	0.82
227_F	230_M	0.834	0.82
392_Q	405_V	0.833	0.82
213_F	223_M	0.833	0.82
27_A	30_R	0.833	0.82
168_G	171_G	0.833	0.82
243_V	247_P	0.833	0.82
326_K	329_L	0.832	0.82
404_T	408_T	0.824	0.81
353_N	359_R	0.823	0.81
345_F	350_K	0.822	0.81
265_F	314_A	0.821	0.81
179_N	292_T	0.818	0.81
78_Y	82_D	0.818	0.81
380_I	388_K	0.809	0.80
162_E	166_G	0.805	0.80
341_Y	344_V	0.802	0.80
298_I	329_L	0.802	0.80
208_D	215_K	0.801	0.80
63_S	69_A	0.797	0.79
198_Q	202_Y	0.797	0.79
409_A	418_K	0.797	0.79
41_Q	87_T	0.795	0.79
173_G	294_L	0.794	0.79
216_D	219_A	0.794	0.79
157_I	182_L	0.793	0.79
353_N	356_T	0.787	0.78
211_R	219_A	0.786	0.78
194_I	199_F	0.782	0.78
109_T	130_L	0.781	0.78
337_Y	342_F	0.779	0.78
3_S	377_N	0.779	0.78
381_M	384_G	0.777	0.77
170_I	174_I	0.777	0.77
294_L	326_K	0.770	0.77
3_S	404_T	0.767	0.77
383_K	410_L	0.767	0.77
169_G	300_N	0.766	0.76
333_V	345_F	0.765	0.76
391_L	405_V	0.765	0.76
238_C	261_A	0.765	0.76
196_W	310_F	0.764	0.76
46_V	53_I	0.764	0.76
245_A	250_R	0.759	0.76
179_N	308_F	0.758	0.76
321_Y	328_L	0.756	0.76
372_T	376_V	0.755	0.75
29_G	36_I	0.751	0.75
220_G	305_R	0.751	0.75
72_L	100_I	0.750	0.75
338_A	349_I	0.748	0.75
259_G	263_T	0.748	0.75
374_Q	396_H	0.747	0.75
233_G	291_L	0.743	0.74
338_A	345_F	0.742	0.74
340_V	343_I	0.742	0.74
64_K	111_N	0.740	0.74
228_P	299_V	0.739	0.74
233_G	288_H	0.737	0.74
210_A	214_A	0.737	0.74
240_A	349_I	0.736	0.74
229_I	337_Y	0.735	0.73
309_S	313_G	0.735	0.73
93_N	99_G	0.733	0.73
347_V	350_K	0.731	0.73
121_Y	262_L	0.729	0.73
397_C	400_R	0.729	0.73
230_M	312_A	0.729	0.73
337_Y	343_I	0.726	0.73
119_P	125_F	0.725	0.72
136_A	139_T	0.724	0.72
317_Y	327_P	0.724	0.72
291_L	295_S	0.723	0.72
82_D	85_T	0.721	0.72
21_A	137_I	0.720	0.72
55_A	73_S	0.720	0.72
110_Y	220_G	0.717	0.72
226_F	292_T	0.714	0.71
372_T	375_D	0.714	0.71
42_A	140_I	0.712	0.71
52_L	70_A	0.712	0.71
237_A	288_H	0.711	0.71
4_F	108_Y	0.709	0.71
202_Y	220_G	0.709	0.71
185_L	278_M	0.709	0.71
338_A	343_I	0.708	0.71
283_L	287_V	0.708	0.71
107_G	135_T	0.706	0.70
349_I	353_N	0.705	0.70
92_N	96_V	0.704	0.70
294_L	298_I	0.704	0.70
394_I	408_T	0.703	0.70
245_A	356_T	0.702	0.70
17_A	278_M	0.701	0.70
207_G	210_A	0.699	0.70
163_W	166_G	0.698	0.70
228_P	316_D	0.698	0.70
180_R	231_M	0.697	0.69
306_S	320_S	0.696	0.69
94_M	98_G	0.694	0.69
90_K	93_N	0.694	0.69
54_F	100_I	0.694	0.69
397_C	402_R	0.694	0.69
349_I	357_P	0.692	0.69
92_N	98_G	0.690	0.69
377_N	381_M	0.690	0.69
249_K	368_L	0.686	0.68
145_I	149_V	0.686	0.68
222_Y	225_G	0.685	0.68
384_G	403_L	0.683	0.68
239_L	244_T	0.683	0.68
231_M	334_G	0.682	0.68
149_V	152_P	0.681	0.68
37_P	40_Y	0.680	0.68
379_N	388_K	0.678	0.67
47_F	213_F	0.677	0.67
202_Y	219_A	0.677	0.67
63_S	66_S	0.677	0.67
151_P	189_H	0.676	0.67
379_N	409_A	0.676	0.67
336_C	418_K	0.676	0.67
209_L	215_K	0.676	0.67
41_Q	44_T	0.676	0.67
290_V	347_V	0.675	0.67
349_I	358_G	0.675	0.67
248_S	362_D	0.673	0.67
142_L	145_I	0.670	0.66
69_A	73_S	0.669	0.66
59_A	70_A	0.668	0.66
97_F	148_V	0.667	0.66
27_A	267_T	0.667	0.66
269_I	312_A	0.667	0.66
92_N	95_A	0.666	0.66
338_A	342_F	0.664	0.66
374_Q	382_L	0.663	0.66
160_F	163_W	0.662	0.66
412_D	416_L	0.661	0.65
334_G	345_F	0.661	0.65
291_L	294_L	0.657	0.65
179_N	296_L	0.656	0.65
341_Y	349_I	0.654	0.65
306_S	330_L	0.654	0.65
382_L	391_L	0.652	0.64
375_D	379_N	0.648	0.64
298_I	333_V	0.648	0.64
163_W	174_I	0.648	0.64
107_G	111_N	0.647	0.64
396_H	403_L	0.647	0.64
369_D	373_V	0.644	0.63
93_N	97_F	0.643	0.63
345_F	353_N	0.641	0.63
62_I	105_I	0.641	0.63
255_G	259_G	0.641	0.63
334_G	337_Y	0.640	0.63
24_I	118_L	0.639	0.63
234_L	288_H	0.639	0.63
176_G	293_G	0.637	0.63
245_A	358_G	0.637	0.63
105_I	109_T	0.636	0.62
331_L	338_A	0.634	0.62
17_A	20_P	0.633	0.62
234_L	260_F	0.633	0.62
23_G	270_T	0.632	0.62
406_K	418_K	0.631	0.62
337_Y	346_Y	0.629	0.62
122_L	130_L	0.629	0.62
85_T	94_M	0.628	0.61
16_I	30_R	0.628	0.61
260_F	276_A	0.627	0.61
22_V	46_V	0.627	0.61
307_G	316_D	0.627	0.61
385_L	405_V	0.626	0.61
142_L	146_F	0.625	0.61
257_M	276_A	0.624	0.61
392_Q	409_A	0.624	0.61
41_Q	48_D	0.624	0.61
384_G	412_D	0.623	0.61
24_I	28_L	0.623	0.61
369_D	372_T	0.622	0.61
363_D	366_E	0.622	0.61
266_I	315_I	0.621	0.61
232_F	235_P	0.621	0.61
39_V	140_I	0.620	0.60
331_L	336_C	0.618	0.60
233_G	237_A	0.616	0.60
396_H	404_T	0.615	0.60
369_D	389_E	0.613	0.60
226_F	296_L	0.613	0.60
227_F	311_S	0.613	0.60
209_L	212_F	0.612	0.59
372_T	379_N	0.612	0.59
238_C	242_V	0.611	0.59
231_M	288_H	0.611	0.59
306_S	321_Y	0.609	0.59
243_V	343_I	0.609	0.59
393_T	403_L	0.608	0.59
16_I	382_L	0.608	0.59
338_A	344_V	0.608	0.59
370_E	375_D	0.607	0.59
354_L	358_G	0.607	0.59
384_G	418_K	0.605	0.59
383_K	392_Q	0.605	0.59
392_Q	410_L	0.605	0.59
199_F	202_Y	0.605	0.59
211_R	324_A	0.603	0.58
15_P	57_G	0.602	0.58
166_G	364_V	0.600	0.58
81_L	98_G	0.600	0.58
404_T	409_A	0.599	0.58
264_A	343_I	0.599	0.58
95_A	139_T	0.596	0.57
125_F	240_A	0.596	0.57
317_Y	328_L	0.594	0.57
373_V	414_A	0.590	0.57
364_V	418_K	0.589	0.57
211_R	218_T	0.588	0.56
59_A	64_K	0.588	0.56
154_Q	187_L	0.586	0.56
101_I	146_F	0.585	0.56
304_I	332_L	0.585	0.56
369_D	383_K	0.584	0.56
97_F	194_I	0.584	0.56
371_N	414_A	0.582	0.56
113_F	116_T	0.581	0.56
77_S	106_A	0.580	0.55
93_N	98_G	0.580	0.55
379_N	392_Q	0.578	0.55
81_L	146_F	0.578	0.55
164_M	194_I	0.578	0.55
222_Y	228_P	0.578	0.55
375_D	378_E	0.577	0.55
60_I	67_N	0.576	0.55
191_L	195_F	0.576	0.55
388_K	394_I	0.575	0.55
403_L	408_T	0.574	0.55
284_L	345_F	0.573	0.55
102_A	150_W	0.573	0.55
115_D	123_G	0.572	0.54
409_A	414_A	0.572	0.54
113_F	130_L	0.571	0.54
343_I	351_A	0.570	0.54
202_Y	217_P	0.570	0.54
360_E	364_V	0.570	0.54
262_L	266_I	0.568	0.54
83_A	86_K	0.567	0.54
379_N	414_A	0.565	0.54
59_A	107_G	0.565	0.54
235_P	238_C	0.564	0.53
391_L	403_L	0.563	0.53
6_Q	10_K	0.562	0.53
296_L	300_N	0.562	0.53
196_W	227_F	0.562	0.53
139_T	143_A	0.561	0.53
137_I	409_A	0.558	0.53
233_G	341_Y	0.557	0.52
370_E	374_Q	0.556	0.52
108_Y	112_R	0.556	0.52
202_Y	216_D	0.555	0.52
161_G	222_Y	0.555	0.52
363_D	368_L	0.555	0.52
406_K	415_L	0.554	0.52
244_T	250_R	0.554	0.52
207_G	213_F	0.552	0.52
378_E	381_M	0.551	0.52
211_R	323_I	0.551	0.52
7_K	62_I	0.550	0.52
339_A	345_F	0.550	0.52
55_A	99_G	0.549	0.51
364_V	368_L	0.549	0.51
99_G	103_G	0.548	0.51
373_V	377_N	0.548	0.51
409_A	413_E	0.547	0.51
376_V	380_I	0.547	0.51
346_Y	351_A	0.547	0.51
392_Q	408_T	0.547	0.51
364_V	371_N	0.545	0.51
304_I	333_V	0.545	0.51
167_L	174_I	0.544	0.51
345_F	351_A	0.544	0.51
196_W	312_A	0.544	0.51
410_L	418_K	0.543	0.51
27_A	313_G	0.543	0.51
220_G	226_F	0.542	0.51
67_N	128_R	0.541	0.50
95_A	98_G	0.540	0.50
389_E	393_T	0.540	0.50
120_E	123_G	0.540	0.50
201_E	221_T	0.539	0.50
375_D	412_D	0.539	0.50
241_M	245_A	0.538	0.50
369_D	375_D	0.538	0.50
174_I	178_F	0.538	0.50
92_N	154_Q	0.537	0.50
239_L	261_A	0.537	0.50
322_G	328_L	0.536	0.50
380_I	409_A	0.536	0.50
47_F	209_L	0.536	0.50
394_I	414_A	0.534	0.50
373_V	396_H	0.534	0.50
281_S	284_L	0.532	0.49
231_M	264_A	0.532	0.49
6_Q	9_G	0.532	0.49
51_P	55_A	0.532	0.49
170_I	365_D	0.532	0.49
283_L	348_L	0.530	0.49
274_E	277_F	0.530	0.49
102_A	109_T	0.528	0.49
82_D	86_K	0.527	0.49
323_I	327_P	0.527	0.49
349_I	354_L	0.527	0.49
22_V	25_I	0.525	0.48
97_F	101_I	0.524	0.48
161_G	201_E	0.523	0.48
393_T	408_T	0.523	0.48
247_P	251_K	0.522	0.48
293_G	297_F	0.521	0.48
246_K	355_K	0.521	0.48
56_I	71_G	0.521	0.48
342_F	349_I	0.520	0.48
383_K	389_E	0.520	0.48
62_I	123_G	0.519	0.48
26_L	315_I	0.516	0.47
222_Y	306_S	0.516	0.47
391_L	411_V	0.516	0.47
278_M	288_H	0.515	0.47
383_K	388_K	0.515	0.47
45_A	74_G	0.515	0.47
102_A	146_F	0.515	0.47
40_Y	44_T	0.515	0.47
363_D	414_A	0.515	0.47
108_Y	409_A	0.514	0.47
184_P	274_E	0.514	0.47
152_P	155_S	0.514	0.47
84_A	88_I	0.512	0.47
180_R	316_D	0.512	0.47
37_P	41_Q	0.511	0.47
159_S	163_W	0.511	0.47
211_R	321_Y	0.509	0.46
172_A	306_S	0.508	0.46
172_A	177_L	0.508	0.46
389_E	411_V	0.508	0.46
43_G	311_S	0.507	0.46
392_Q	403_L	0.506	0.46
195_F	233_G	0.506	0.46
57_G	100_I	0.504	0.46
408_T	411_V	0.504	0.46
379_N	393_T	0.503	0.46
223_M	227_F	0.502	0.45
408_T	418_K	0.502	0.45
215_K	218_T	0.502	0.45
158_N	162_E	0.500	0.45
100_I	238_C	0.500	0.45

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3qnqA	2	0.792	100	0.655	Contact Map
1ibaA	1	0.1659	99.9	0.821	Contact Map
3bp3A	1	0.177	99.9	0.824	Contact Map
3ipjA	1	0.1792	99.8	0.837	Contact Map
3wdoA	1	0.7876	59.5	0.969	Contact Map
4pypA	1	0.7257	37.8	0.973	Contact Map
4ea3A	2	0.1814	37.3	0.973	Contact Map
3cw2K	1	0.2168	33.6	0.974	Contact Map
2d74B	1	0.2102	27.8	0.975	Contact Map
4mt1A	3	0.2854	25.7	0.975	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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