YFMM - BACSU - GREMLIN Contacts

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YFMM - Uncharacterized ABC transporter ATP-binding protein YfmM

UniProt:	O34512	Sequences: MSILSVKDLSHGFGDRAIFNNVSFRLLKGEHVGLIGANGEGKSTFMNIITGKLEPDEGKVEWSKNVRVGYLDQHTVLEKGKSIRDVLKDAFHYLFAMEEEMNEIYNKMGEADPDELEKLLEEVGVIQDALTNNDFYVIDSKVEEIARGLGLSDIGLERDVTDLSGGQRTKVLLAKLLLEKPEILLLDEPTNYLDEQHIEWLKRYLQEYENAFILISHDIPFLNSVINLIYHVENQELTRYVGDYHQFMEVYEVKKQQLEAAYKKQQQEVAELKDFVARNKARVSTRNMAMSRQKKLDKMDMIELAAEKPKPEFHFKPARTSGKLIFETKDLVIGYDSPLSRPLNLRMERGQKIALYGANGIGKTTLLKSLLGEIQPLEGSVERGEHIYTGYFEQEVKETNNNTCIEEVWSEFPSYTQYEIRAALAKCGLTTKHIESRVSVLSGGEKAKVRLCKLINSETNLLVLDEPTNHLDADAKEELKRALKEYKGSILLISHEPDFYMDIATETWNCESWTTKVL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	518 (406)
Sequences:	3453 (2282)
Seq/√Len:	113.3

ECOLI - UUP YHES ETTA GSIA YBHF XYLG YBIT ALSA MGLA MODF YPHE YEJF YTFR YHIH LSRA ARAG RBSA
BACSU - YFMM YKPA YDIF YFMR EXPZ YUFO YKOD RBSA
HALSA - Q9HMC1 Q9HR21
SULSO - Y1893 Y2030 Q980K5 Q97UG5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
223_N	245_H	5.150	1.00
100_E	122_E	4.627	1.00
330_D	342_P	3.801	1.00
328_T	331_L	3.780	1.00
102_N	105_Y	3.635	1.00
8_D	21_N	3.328	1.00
46_M	215_I	3.201	1.00
134_D	137_V	3.139	1.00
328_T	345_L	3.021	1.00
329_K	380_S	2.993	1.00
333_I	377_L	2.854	1.00
293_Q	297_D	2.686	1.00
6_V	9_L	2.664	1.00
333_I	369_S	2.661	1.00
347_M	353_I	2.637	1.00
334_G	377_L	2.541	1.00
82_S	85_D	2.524	1.00
330_D	344_N	2.516	1.00
92_H	96_A	2.468	1.00
273_K	301_M	2.454	1.00
228_L	239_R	2.449	1.00
130_L	135_F	2.414	1.00
238_T	254_K	2.366	1.00
246_Q	250_V	2.324	1.00
30_E	228_L	2.224	1.00
87_L	90_A	2.222	1.00
6_V	49_I	2.210	1.00
103_E	107_K	2.174	1.00
246_Q	249_E	2.168	1.00
273_K	277_A	2.150	1.00
33_G	229_I	2.145	1.00
129_A	133_N	2.133	1.00
158_R	162_D	2.103	1.00
338_P	341_R	2.095	1.00
104_I	119_L	2.066	1.00
100_E	103_E	2.039	1.00
141_K	180_K	2.012	1.00
85_D	88_K	1.987	1.00
97_M	126_I	1.945	1.00
117_E	121_E	1.944	1.00
17_A	20_N	1.933	1.00
402_N	407_E	1.907	1.00
112_D	115_E	1.893	1.00
6_V	24_F	1.881	1.00
49_I	213_I	1.841	1.00
332_V	378_E	1.840	1.00
240_Y	254_K	1.837	1.00
206_Q	224_S	1.836	1.00
226_I	229_I	1.835	1.00
396_V	399_T	1.831	1.00
262_Y	266_Q	1.818	1.00
180_K	209_E	1.808	1.00
282_R	285_T	1.802	1.00
99_E	102_N	1.799	1.00
9_L	55_P	1.773	1.00
280_K	293_Q	1.767	1.00
10_S	57_E	1.763	1.00
113_P	116_L	1.737	1.00
93_Y	96_A	1.712	1.00
364_T	368_K	1.709	1.00
369_S	381_V	1.702	1.00
20_N	236_E	1.700	1.00
7_K	59_K	1.690	1.00
98_E	102_N	1.663	1.00
368_K	373_E	1.660	1.00
30_E	227_N	1.658	1.00
202_K	224_S	1.649	1.00
101_M	105_Y	1.627	1.00
324_L	327_E	1.627	1.00
84_R	87_L	1.625	1.00
290_M	293_Q	1.624	1.00
327_E	382_E	1.610	1.00
86_V	89_D	1.595	1.00
331_L	376_P	1.585	1.00
276_V	296_L	1.582	1.00
249_E	253_V	1.563	1.00
84_R	90_A	1.544	1.00
250_V	254_K	1.537	1.00
231_H	251_Y	1.533	1.00
47_N	52_K	1.525	1.00
33_G	222_L	1.515	1.00
26_L	183_I	1.512	1.00
19_F	22_V	1.506	1.00
80_G	159_D	1.491	1.00
327_E	346_R	1.470	1.00
232_V	237_L	1.461	1.00
223_N	243_D	1.459	1.00
86_V	90_A	1.457	1.00
257_Q	261_A	1.457	1.00
268_E	271_E	1.451	1.00
291_S	294_K	1.440	1.00
276_V	293_Q	1.426	1.00
100_E	104_I	1.423	1.00
203_R	207_E	1.414	1.00
34_L	232_V	1.413	1.00
283_V	286_R	1.407	1.00
85_D	90_A	1.402	1.00
250_V	253_V	1.399	1.00
87_L	91_F	1.398	1.00
369_S	376_P	1.398	1.00
62_W	66_V	1.396	1.00
134_D	141_K	1.394	1.00
275_F	288_M	1.390	1.00
46_M	185_L	1.382	1.00
101_M	104_I	1.373	1.00
168_R	395_E	1.369	1.00
43_S	47_N	1.367	1.00
340_S	343_L	1.366	1.00
333_I	374_I	1.363	1.00
98_E	105_Y	1.363	1.00
329_K	344_N	1.348	1.00
279_N	285_T	1.347	1.00
159_D	162_D	1.344	1.00
328_T	370_L	1.342	1.00
98_E	101_M	1.339	1.00
396_V	400_N	1.320	1.00
282_R	286_R	1.312	1.00
252_E	256_Q	1.305	1.00
11_H	56_D	1.302	0.99
334_G	338_P	1.302	0.99
96_A	100_E	1.301	0.99
84_R	89_D	1.300	0.99
26_L	32_V	1.298	0.99
294_K	297_D	1.295	0.99
368_K	374_I	1.283	0.99
329_K	382_E	1.277	0.99
333_I	365_T	1.277	0.99
84_R	88_K	1.276	0.99
8_D	23_S	1.274	0.99
11_H	44_T	1.273	0.99
205_L	225_V	1.266	0.99
69_G	176_L	1.266	0.99
253_V	256_Q	1.261	0.99
326_F	383_R	1.261	0.99
323_K	348_E	1.251	0.99
146_A	156_L	1.250	0.99
112_D	116_L	1.246	0.99
253_V	257_Q	1.242	0.99
127_Q	131_T	1.242	0.99
81_K	89_D	1.242	0.99
11_H	53_L	1.240	0.99
105_Y	108_M	1.239	0.99
10_S	21_N	1.237	0.99
9_L	48_I	1.232	0.99
242_G	246_Q	1.226	0.99
275_F	292_R	1.225	0.99
95_F	98_E	1.222	0.99
82_S	86_V	1.221	0.99
11_H	48_I	1.218	0.99
77_L	82_S	1.215	0.99
231_H	247_F	1.209	0.99
279_N	282_R	1.206	0.99
185_L	213_I	1.196	0.99
22_V	237_L	1.195	0.99
80_G	161_T	1.190	0.99
24_F	230_Y	1.190	0.99
214_L	226_I	1.186	0.99
369_S	377_L	1.180	0.99
163_L	171_V	1.174	0.99
321_S	325_I	1.167	0.99
48_I	60_V	1.166	0.99
267_Q	270_A	1.166	0.99
63_S	66_V	1.156	0.99
268_E	272_L	1.152	0.99
160_V	171_V	1.150	0.99
97_M	100_E	1.149	0.99
105_Y	123_V	1.133	0.99
243_D	246_Q	1.127	0.99
331_L	369_S	1.126	0.99
376_P	381_V	1.126	0.99
122_E	126_I	1.125	0.99
259_E	263_K	1.123	0.98
33_G	226_I	1.122	0.98
48_I	55_P	1.122	0.98
274_D	278_R	1.118	0.98
97_M	101_M	1.117	0.98
125_V	129_A	1.117	0.98
79_K	82_S	1.108	0.98
205_L	212_F	1.101	0.98
86_V	91_F	1.099	0.98
81_K	86_V	1.098	0.98
82_S	87_L	1.092	0.98
121_E	125_V	1.092	0.98
128_D	131_T	1.083	0.98
256_Q	260_A	1.081	0.98
31_H	227_N	1.075	0.98
183_I	213_I	1.074	0.98
111_A	115_E	1.073	0.98
107_K	110_E	1.070	0.98
8_D	57_E	1.067	0.98
100_E	107_K	1.065	0.98
258_L	302_I	1.064	0.98
265_Q	302_I	1.061	0.98
249_E	252_E	1.060	0.98
230_Y	237_L	1.059	0.98
185_L	215_I	1.053	0.98
275_F	279_N	1.040	0.98
52_K	72_D	1.040	0.98
99_E	103_E	1.040	0.98
256_Q	259_E	1.039	0.98
262_Y	265_Q	1.035	0.97
334_G	369_S	1.032	0.97
122_E	125_V	1.032	0.97
88_K	95_F	1.030	0.97
4_L	62_W	1.030	0.97
81_K	85_D	1.027	0.97
128_D	132_N	1.025	0.97
183_I	211_A	1.021	0.97
93_Y	133_N	1.020	0.97
230_Y	239_R	1.014	0.97
299_M	302_I	1.012	0.97
78_E	82_S	1.003	0.97
294_K	298_K	1.003	0.97
289_A	293_Q	0.996	0.97
302_I	305_A	0.996	0.97
107_K	115_E	0.990	0.97
103_E	106_N	0.990	0.97
62_W	68_V	0.987	0.97
91_F	98_E	0.984	0.97
340_S	369_S	0.984	0.97
277_A	280_K	0.981	0.96
6_V	60_V	0.977	0.96
216_S	222_L	0.975	0.96
151_L	155_G	0.973	0.96
46_M	50_T	0.973	0.96
328_T	381_V	0.971	0.96
330_D	378_E	0.965	0.96
319_R	388_Y	0.965	0.96
152_S	155_G	0.964	0.96
66_V	183_I	0.964	0.96
335_Y	374_I	0.963	0.96
67_R	182_E	0.960	0.96
324_L	382_E	0.956	0.96
281_A	285_T	0.955	0.96
22_V	232_V	0.951	0.96
289_A	294_K	0.951	0.96
29_G	211_A	0.950	0.96
81_K	84_R	0.948	0.96
155_G	158_R	0.948	0.96
34_L	237_L	0.945	0.96
270_A	274_D	0.938	0.95
272_L	295_K	0.934	0.95
332_V	340_S	0.932	0.95
155_G	163_L	0.931	0.95
266_Q	269_V	0.928	0.95
151_L	163_L	0.924	0.95
30_E	239_R	0.923	0.95
291_S	295_K	0.920	0.95
55_P	60_V	0.920	0.95
403_T	406_E	0.916	0.95
399_T	407_E	0.916	0.95
121_E	124_G	0.911	0.95
203_R	206_Q	0.906	0.95
108_M	116_L	0.903	0.94
286_R	290_M	0.898	0.94
322_G	384_G	0.896	0.94
94_L	98_E	0.891	0.94
12_G	17_A	0.891	0.94
322_G	325_I	0.890	0.94
264_K	267_Q	0.890	0.94
77_L	83_I	0.889	0.94
11_H	55_P	0.886	0.94
370_L	383_R	0.883	0.94
21_N	236_E	0.881	0.94
275_F	282_R	0.879	0.94
383_R	387_I	0.878	0.94
104_I	126_I	0.876	0.93
196_Q	358_A	0.874	0.93
275_F	281_A	0.873	0.93
13_F	53_L	0.872	0.93
102_N	106_N	0.869	0.93
370_L	381_V	0.866	0.93
124_G	128_D	0.866	0.93
97_M	105_Y	0.865	0.93
104_I	107_K	0.865	0.93
110_E	113_P	0.865	0.93
326_F	347_M	0.858	0.93
280_K	285_T	0.855	0.93
96_A	99_E	0.855	0.93
321_S	387_I	0.851	0.92
332_V	341_R	0.849	0.92
291_S	296_L	0.848	0.92
111_A	116_L	0.848	0.92
296_L	302_I	0.847	0.92
97_M	129_A	0.847	0.92
290_M	294_K	0.847	0.92
283_V	290_M	0.847	0.92
357_G	363_K	0.847	0.92
325_I	387_I	0.846	0.92
399_T	402_N	0.843	0.92
332_V	342_P	0.843	0.92
275_F	283_V	0.838	0.92
83_I	90_A	0.836	0.92
277_A	282_R	0.835	0.92
106_N	109_G	0.834	0.92
94_L	97_M	0.826	0.91
363_K	394_Q	0.823	0.91
107_K	119_L	0.822	0.91
75_T	168_R	0.820	0.91
89_D	92_H	0.819	0.91
242_G	250_V	0.817	0.91
291_S	298_K	0.815	0.91
4_L	183_I	0.810	0.90
291_S	299_M	0.809	0.90
140_S	144_E	0.809	0.90
287_N	291_S	0.809	0.90
113_P	117_E	0.807	0.90
279_N	288_M	0.805	0.90
138_I	142_V	0.802	0.90
104_I	108_M	0.799	0.90
78_E	83_I	0.795	0.90
269_V	296_L	0.794	0.90
371_L	389_T	0.793	0.90
281_A	284_S	0.793	0.90
34_L	213_I	0.792	0.89
84_R	91_F	0.790	0.89
83_I	163_L	0.789	0.89
9_L	19_F	0.788	0.89
117_E	120_L	0.787	0.89
384_G	387_I	0.785	0.89
279_N	283_V	0.775	0.88
282_R	288_M	0.773	0.88
303_E	306_A	0.773	0.88
255_K	259_E	0.772	0.88
26_L	213_I	0.771	0.88
84_R	142_V	0.769	0.88
138_I	178_L	0.769	0.88
78_E	81_K	0.768	0.88
114_D	117_E	0.768	0.88
330_D	333_I	0.767	0.88
115_E	119_L	0.759	0.87
166_G	360_G	0.757	0.87
334_G	339_L	0.756	0.87
32_V	230_Y	0.752	0.87
106_N	110_E	0.752	0.87
295_K	299_M	0.751	0.87
97_M	104_I	0.751	0.87
290_M	298_K	0.751	0.87
288_M	291_S	0.749	0.87
202_K	219_I	0.749	0.87
335_Y	365_T	0.745	0.86
277_A	281_A	0.744	0.86
93_Y	129_A	0.743	0.86
264_K	268_E	0.740	0.86
402_N	406_E	0.739	0.86
358_A	361_I	0.738	0.86
76_V	79_K	0.737	0.86
69_G	73_Q	0.736	0.86
124_G	127_Q	0.734	0.86
258_L	304_L	0.733	0.86
258_L	261_A	0.733	0.86
160_V	168_R	0.732	0.85
10_S	17_A	0.732	0.85
110_E	114_D	0.729	0.85
332_V	338_P	0.728	0.85
116_L	119_L	0.728	0.85
357_G	360_G	0.726	0.85
80_G	83_I	0.725	0.85
405_I	408_V	0.722	0.85
98_E	108_M	0.718	0.84
348_E	351_Q	0.717	0.84
77_L	81_K	0.716	0.84
77_L	86_V	0.716	0.84
300_D	303_E	0.716	0.84
80_G	87_L	0.716	0.84
98_E	104_I	0.715	0.84
319_R	386_H	0.714	0.84
141_K	144_E	0.713	0.84
298_K	301_M	0.713	0.84
284_S	290_M	0.712	0.84
143_E	156_L	0.711	0.84
158_R	163_L	0.711	0.84
83_I	171_V	0.711	0.84
154_I	158_R	0.710	0.84
347_M	351_Q	0.709	0.84
272_L	282_R	0.707	0.83
296_L	305_A	0.704	0.83
149_L	174_A	0.703	0.83
105_Y	109_G	0.701	0.83
308_K	311_P	0.701	0.83
275_F	286_R	0.699	0.83
82_S	90_A	0.697	0.83
275_F	285_T	0.695	0.82
82_S	89_D	0.693	0.82
265_Q	296_L	0.690	0.82
93_Y	100_E	0.689	0.82
166_G	359_N	0.689	0.82
273_K	296_L	0.687	0.82
137_V	141_K	0.687	0.82
272_L	275_F	0.685	0.81
265_Q	269_V	0.685	0.81
274_D	277_A	0.684	0.81
269_V	272_L	0.683	0.81
333_I	340_S	0.682	0.81
362_G	394_Q	0.682	0.81
76_V	81_K	0.678	0.81
324_L	346_R	0.677	0.81
91_F	94_L	0.674	0.80
268_E	299_M	0.674	0.80
160_V	172_L	0.674	0.80
323_K	327_E	0.672	0.80
47_N	53_L	0.670	0.80
58_G	73_Q	0.668	0.80
286_R	291_S	0.667	0.80
110_E	117_E	0.666	0.80
82_S	91_F	0.666	0.80
280_K	286_R	0.664	0.79
331_L	370_L	0.664	0.79
143_E	153_D	0.664	0.79
369_S	374_I	0.663	0.79
269_V	301_M	0.662	0.79
164_S	360_G	0.661	0.79
293_Q	296_L	0.657	0.79
88_K	98_E	0.657	0.79
372_G	381_V	0.655	0.79
360_G	363_K	0.653	0.78
111_A	114_D	0.653	0.78
221_F	225_V	0.652	0.78
101_M	126_I	0.650	0.78
279_N	286_R	0.645	0.77
90_A	101_M	0.645	0.77
27_L	30_E	0.644	0.77
164_S	363_K	0.643	0.77
166_G	362_G	0.642	0.77
279_N	284_S	0.642	0.77
322_G	385_E	0.641	0.77
94_L	133_N	0.640	0.77
78_E	89_D	0.640	0.77
151_L	154_I	0.639	0.77
130_L	134_D	0.638	0.77
83_I	87_L	0.637	0.77
318_A	388_Y	0.636	0.76
97_M	102_N	0.636	0.76
38_N	217_H	0.632	0.76
306_A	311_P	0.632	0.76
7_K	61_E	0.631	0.76
342_P	378_E	0.630	0.76
393_E	396_V	0.627	0.75
360_G	365_T	0.627	0.75
359_N	365_T	0.625	0.75
272_L	286_R	0.625	0.75
294_K	300_D	0.624	0.75
118_K	122_E	0.624	0.75
214_L	225_V	0.624	0.75
32_V	228_L	0.623	0.75
357_G	362_G	0.623	0.75
108_M	123_V	0.620	0.75
50_T	70_Y	0.619	0.75
44_T	53_L	0.619	0.75
118_K	121_E	0.618	0.74
62_W	65_N	0.618	0.74
79_K	83_I	0.616	0.74
100_E	126_I	0.616	0.74
281_A	293_Q	0.613	0.74
294_K	302_I	0.613	0.74
88_K	139_D	0.613	0.74
289_A	296_L	0.609	0.73
288_M	292_R	0.609	0.73
3_I	63_S	0.608	0.73
37_A	40_E	0.606	0.73
92_H	97_M	0.603	0.73
355_L	358_A	0.603	0.73
101_M	108_M	0.602	0.72
261_A	302_I	0.600	0.72
126_I	129_A	0.600	0.72
164_S	394_Q	0.599	0.72
298_K	305_A	0.597	0.72
69_G	181_P	0.597	0.72
244_Y	247_F	0.597	0.72
369_S	375_Q	0.596	0.72
95_F	102_N	0.595	0.72
29_G	209_E	0.595	0.72
397_K	400_N	0.594	0.71
349_R	392_F	0.594	0.71
281_A	286_R	0.593	0.71
83_I	89_D	0.592	0.71
276_V	305_A	0.591	0.71
34_L	230_Y	0.590	0.71
325_I	384_G	0.589	0.71
118_K	336_D	0.589	0.71
281_A	289_A	0.589	0.71
130_L	136_Y	0.589	0.71
176_L	184_L	0.587	0.71
374_I	377_L	0.586	0.70
3_I	211_A	0.585	0.70
228_L	241_V	0.584	0.70
220_P	224_S	0.580	0.70
5_S	61_E	0.580	0.70
60_V	183_I	0.579	0.70
115_E	118_K	0.578	0.69
51_G	58_G	0.577	0.69
279_N	293_Q	0.577	0.69
170_K	231_H	0.576	0.69
14_G	17_A	0.576	0.69
240_Y	247_F	0.575	0.69
298_K	302_I	0.575	0.69
372_G	389_T	0.573	0.69
166_G	394_Q	0.572	0.69
325_I	349_R	0.570	0.68
404_C	407_E	0.570	0.68
123_V	130_L	0.570	0.68
104_I	122_E	0.570	0.68
19_F	232_V	0.570	0.68
293_Q	299_M	0.568	0.68
328_T	344_N	0.566	0.68
272_L	283_V	0.566	0.68
301_M	305_A	0.566	0.68
87_L	146_A	0.564	0.68
91_F	101_M	0.563	0.67
79_K	161_T	0.563	0.67
131_T	136_Y	0.561	0.67
298_K	303_E	0.560	0.67
286_R	292_R	0.559	0.67
120_L	124_G	0.559	0.67
198_I	395_E	0.553	0.66
149_L	200_W	0.552	0.66
94_L	101_M	0.551	0.66
85_D	100_E	0.549	0.65
48_I	232_V	0.548	0.65
164_S	362_G	0.548	0.65
360_G	394_Q	0.547	0.65
101_M	123_V	0.547	0.65
216_S	354_A	0.546	0.65
169_T	279_N	0.546	0.65
139_D	143_E	0.546	0.65
248_M	252_E	0.546	0.65
335_Y	369_S	0.546	0.65
95_F	99_E	0.545	0.65
102_N	108_M	0.545	0.65
291_S	297_D	0.544	0.65
212_F	225_V	0.543	0.65
293_Q	300_D	0.542	0.65
80_G	85_D	0.541	0.64
257_Q	260_A	0.540	0.64
19_F	45_F	0.539	0.64
166_G	365_T	0.538	0.64
107_K	122_E	0.538	0.64
285_T	293_Q	0.538	0.64
269_V	299_M	0.538	0.64
120_L	127_Q	0.537	0.64
71_L	176_L	0.536	0.64
49_I	230_Y	0.535	0.64
70_Y	73_Q	0.535	0.64
107_K	114_D	0.534	0.63
3_I	393_E	0.534	0.63
142_V	352_K	0.532	0.63
110_E	116_L	0.531	0.63
226_I	230_Y	0.528	0.63
22_V	45_F	0.528	0.63
335_Y	339_L	0.528	0.63
85_D	89_D	0.527	0.62
149_L	197_H	0.527	0.62
165_G	394_Q	0.526	0.62
289_A	292_R	0.526	0.62
166_G	357_G	0.525	0.62
208_Y	212_F	0.525	0.62
191_N	218_D	0.525	0.62
220_P	223_N	0.525	0.62
283_V	291_S	0.524	0.62
403_T	407_E	0.524	0.62
11_H	18_I	0.524	0.62
299_M	305_A	0.523	0.62
294_K	299_M	0.521	0.61
151_L	171_V	0.520	0.61
83_I	86_V	0.520	0.61
271_E	275_F	0.520	0.61
79_K	89_D	0.519	0.61
280_K	284_S	0.519	0.61
278_R	281_A	0.518	0.61
167_Q	395_E	0.518	0.61
33_G	230_Y	0.518	0.61
291_S	300_D	0.517	0.61
375_Q	383_R	0.517	0.61
7_K	23_S	0.516	0.61
93_Y	97_M	0.516	0.61
320_T	349_R	0.515	0.61
85_D	157_E	0.515	0.61
86_V	175_K	0.515	0.61
119_L	123_V	0.515	0.61
265_Q	276_V	0.515	0.61
260_A	264_K	0.514	0.60
3_I	32_V	0.513	0.60
180_K	208_Y	0.513	0.60
317_P	320_T	0.513	0.60
92_H	95_F	0.512	0.60
109_G	113_P	0.512	0.60
272_L	276_V	0.510	0.60
22_V	29_G	0.510	0.60
108_M	115_E	0.509	0.60
265_Q	301_M	0.508	0.60
43_S	46_M	0.508	0.60
170_K	197_H	0.506	0.59
38_N	191_N	0.506	0.59
3_I	66_V	0.506	0.59
62_W	183_I	0.505	0.59
109_G	115_E	0.505	0.59
99_E	107_K	0.505	0.59
163_L	282_R	0.505	0.59
76_V	213_I	0.505	0.59
110_E	115_E	0.504	0.59
146_A	151_L	0.504	0.59
114_D	119_L	0.504	0.59
294_K	305_A	0.503	0.59
52_K	203_R	0.503	0.59
85_D	91_F	0.503	0.59
365_T	394_Q	0.503	0.59
11_H	168_R	0.502	0.59
6_V	19_F	0.500	0.58
259_E	304_L	0.500	0.58

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4finA	2	0.9459	100	0.275	Contact Map
2iw3A	2	0.834	100	0.342	Contact Map
4q9hA	1	0.9189	100	0.347	Contact Map
4f4cA	1	0.9054	100	0.354	Contact Map
1yqtA	1	0.8514	100	0.367	Contact Map
3bk7A	1	0.8668	100	0.367	Contact Map
3ozxA	1	0.861	100	0.373	Contact Map
3j16B	1	0.8803	100	0.398	Contact Map
3ux8A	2	0.7529	100	0.425	Contact Map
2vf7A	2	0.8378	100	0.526	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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