GREMLIN Database
RECDL - ATP-dependent RecD-like DNA helicase
UniProt: O34481 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 798 (694)
Sequences: 2276 (1811)
Seq/√Len: 68.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
364_L501_L6.7781.00
700_L718_A4.8521.00
27_N30_N4.8391.00
531_M719_I4.2511.00
136_V139_D4.1781.00
459_A462_L3.8431.00
308_N468_N3.7741.00
250_E748_Q3.7301.00
625_I679_F3.7131.00
377_I418_M3.6291.00
332_L355_Q3.5981.00
309_V464_I3.1661.00
662_V679_F3.1521.00
661_V664_F3.1361.00
451_G454_L3.1001.00
663_S666_G3.0971.00
502_L509_T3.0231.00
385_G424_L2.9461.00
339_E351_K2.9301.00
128_N132_A2.8701.00
365_L376_V2.8111.00
257_D260_S2.7971.00
67_T88_K2.7461.00
346_Y354_I2.7431.00
462_L467_A2.6821.00
551_R732_E2.6661.00
185_Y203_D2.6521.00
145_K149_D2.6511.00
313_V507_I2.6361.00
408_A432_L2.6331.00
312_R315_H2.5921.00
125_S128_N2.5811.00
564_V568_A2.5761.00
347_A514_D2.5741.00
406_V451_G2.5731.00
363_L510_V2.5591.00
430_H466_L2.5581.00
534_G712_R2.4941.00
580_V598_L2.4761.00
241_C249_I2.4681.00
645_T668_E2.4551.00
181_I185_Y2.4521.00
73_V83_Q2.4101.00
475_P478_I2.3781.00
429_I462_L2.3771.00
456_I470_L2.3631.00
621_T646_S2.3601.00
335_L339_E2.3491.00
251_T295_G2.3491.00
660_A664_F2.3461.00
313_V362_M2.3421.00
118_I126_A2.3311.00
454_L474_I2.2661.00
565_V568_A2.2471.00
111_G115_A2.2201.00
305_A468_N2.2171.00
138_Y148_A2.2081.00
71_K83_Q2.1761.00
582_A591_I2.1671.00
696_P724_K2.1611.00
188_E191_E2.1571.00
69_Y86_H2.1471.00
126_A130_I2.1411.00
99_I116_E2.1271.00
629_V678_Q2.1061.00
347_A516_Y2.1061.00
617_V681_H2.0941.00
35_L84_A2.0861.00
659_M664_F2.0831.00
530_Q535_L2.0661.00
341_R382_E2.0571.00
309_V467_A2.0411.00
248_Y296_R2.0241.00
349_S513_T2.0241.00
346_Y379_G1.9971.00
463_D493_G1.9771.00
351_K355_Q1.9711.00
127_I130_I1.9671.00
191_E195_E1.9641.00
445_E472_K1.9601.00
64_E89_K1.9571.00
564_V570_K1.9511.00
659_M670_T1.9441.00
581_L687_I1.9291.00
356_K363_L1.9271.00
75_H79_G1.9241.00
736_E740_K1.8991.00
182_Y185_Y1.8931.00
687_I700_L1.8851.00
53_V84_A1.8831.00
467_A471_F1.8791.00
606_K609_R1.8721.00
604_P620_R1.8541.00
636_V671_F1.8491.00
456_I482_I1.8401.00
599_Q620_R1.8251.00
625_I662_V1.8251.00
503_A752_K1.8241.00
285_G292_I1.8221.00
752_K756_S1.8211.00
527_L530_Q1.8211.00
528_A720_T1.8191.00
305_A465_W1.8161.00
349_S514_D1.8151.00
197_P200_L1.7911.00
384_Y453_L1.7711.00
28_D114_T1.7661.00
37_V68_F1.7481.00
468_N472_K1.7401.00
199_Q203_D1.7401.00
634_N675_D1.7341.00
356_K510_V1.7321.00
631_Q678_Q1.7271.00
300_P304_Y1.7181.00
694_E723_K1.7161.00
599_Q681_H1.6911.00
354_I379_G1.6891.00
591_I686_S1.6861.00
454_L478_I1.6750.99
255_I277_A1.6740.99
144_S147_K1.6690.99
71_K85_E1.6680.99
565_V699_V1.6620.99
354_I376_V1.6570.99
459_A482_I1.6540.99
208_G212_A1.6430.99
336_G339_E1.6380.99
474_I478_I1.6380.99
233_I277_A1.6350.99
577_D696_P1.6310.99
251_T278_A1.6160.99
404_P452_K1.6100.99
563_K567_N1.6080.99
569_L573_Y1.6040.99
593_E596_V1.6000.99
122_L126_A1.5950.99
463_D466_L1.5790.99
564_V569_L1.5770.99
349_S352_E1.5750.99
232_A262_L1.5720.99
453_L481_I1.5700.99
474_I480_I1.5690.99
597_M600_D1.5680.99
482_I501_L1.5620.99
378_R382_E1.5570.99
35_L53_V1.5520.99
621_T647_I1.5500.99
338_L383_L1.5450.99
53_V68_F1.5390.99
451_G478_I1.5390.99
352_E356_K1.5360.99
461_M688_H1.5250.99
715_L735_L1.5170.99
750_S753_N1.5150.99
624_K641_I1.5140.99
362_M482_I1.5110.99
108_E111_G1.5090.99
357_A365_L1.5070.99
47_E102_L1.5070.99
327_P330_E1.5060.99
635_N667_N1.4990.99
26_H33_T1.4930.99
68_F82_F1.4890.99
67_T90_E1.4880.99
281_I290_I1.4700.99
24_I122_L1.4660.99
619_Y644_I1.4650.99
336_G351_K1.4630.99
628_L680_T1.4500.98
697_I725_F1.4390.98
410_P492_V1.4330.98
182_Y186_E1.4310.98
491_S497_V1.4220.98
341_R386_E1.4220.98
585_Y680_T1.4190.98
229_V277_A1.3990.98
121_K139_D1.3950.98
167_S171_F1.3940.98
311_K315_H1.3920.98
626_L689_K1.3900.98
408_A454_L1.3880.98
611_E620_R1.3880.98
224_N276_D1.3760.98
487_D532_K1.3750.98
72_I80_L1.3700.98
565_V569_L1.3670.98
568_A572_G1.3660.98
619_Y679_F1.3660.98
408_A456_I1.3650.98
368_G371_T1.3610.98
285_G290_I1.3590.98
598_L602_L1.3510.98
313_V501_L1.3500.98
603_N620_R1.3480.98
309_V471_F1.3470.98
412_G428_T1.3390.97
659_M662_V1.3330.97
524_I527_L1.3210.97
20_V35_L1.3200.97
28_D84_A1.3190.97
298_Y754_R1.3180.97
122_L129_K1.3130.97
631_Q634_N1.3110.97
702_V728_L1.3100.97
699_V727_I1.3070.97
374_T421_S1.3040.97
114_T117_E1.2890.97
582_A594_L1.2890.97
66_Y87_F1.2890.97
149_D153_G1.2890.97
687_I718_A1.2890.97
557_I561_V1.2830.97
570_K573_Y1.2800.97
250_E253_Q1.2790.97
247_T298_Y1.2780.97
317_A508_P1.2770.97
362_M480_I1.2730.97
645_T663_S1.2720.97
696_P723_K1.2680.96
417_R421_S1.2660.96
110_I151_L1.2640.96
630_N638_N1.2590.96
364_L507_I1.2580.96
560_V563_K1.2580.96
279_N282_I1.2550.96
247_T464_I1.2460.96
688_H714_L1.2420.96
412_G639_G1.2400.96
407_L418_M1.2380.96
655_E659_M1.2370.96
133_D136_V1.2330.96
560_V568_A1.2300.96
707_Y737_W1.2290.96
230_K283_A1.2220.96
411_T414_A1.2220.96
459_A467_A1.2220.96
537_P739_V1.2150.95
357_A380_I1.2150.95
99_I120_K1.2130.95
335_L351_K1.2130.95
282_I285_G1.2110.95
152_A156_Q1.2080.95
722_A726_L1.2050.95
334_A338_L1.2040.95
381_V385_G1.1920.95
552_C560_V1.1890.95
557_I703_V1.1860.95
427_V431_R1.1850.95
548_S552_C1.1780.95
354_I380_I1.1740.95
549_F730_G1.1690.94
377_I455_I1.1690.94
30_N121_K1.1660.94
645_T661_V1.1660.94
57_F84_A1.1660.94
299_F302_L1.1630.94
181_I204_V1.1620.94
726_L729_C1.1610.94
363_L509_T1.1520.94
454_L480_I1.1520.94
410_P428_T1.1510.94
610_R621_T1.1470.94
174_G177_L1.1460.94
627_Q671_F1.1460.94
361_P479_Q1.1240.93
253_Q748_Q1.1210.93
585_Y591_I1.1200.93
129_K136_V1.1200.93
181_I186_E1.1190.93
543_P549_F1.1180.93
164_I189_T1.1180.93
558_K565_V1.1160.93
661_V668_E1.1160.93
121_K140_V1.1140.93
584_M590_G1.1120.93
499_R503_A1.1100.93
568_A573_Y1.1070.93
334_A386_E1.1070.93
583_P590_G1.1060.93
487_D511_R1.1060.93
134_A152_A1.1050.93
34_V54_T1.1030.93
94_T97_G1.1010.92
644_I660_A1.1010.92
193_I197_P1.1000.92
204_V208_G1.0990.92
184_A203_D1.0920.92
412_G630_N1.0910.92
338_L342_M1.0820.92
153_G200_L1.0800.92
84_A87_F1.0780.92
353_A365_L1.0780.92
155_L159_Q1.0730.91
585_Y592_N1.0690.91
209_F213_D1.0670.91
98_I127_I1.0670.91
732_E736_E1.0640.91
702_V715_L1.0640.91
363_L481_I1.0630.91
580_V644_I1.0630.91
417_R420_E1.0580.91
307_Q754_R1.0550.91
249_I299_F1.0510.91
527_L547_R1.0470.90
196_N227_E1.0460.90
251_T282_I1.0460.90
21_N50_A1.0450.90
313_V480_I1.0450.90
193_I200_L1.0440.90
474_I477_H1.0440.90
593_E597_M1.0430.90
148_A152_A1.0420.90
283_A286_E1.0410.90
559_E563_K1.0400.90
660_A665_D1.0390.90
700_L728_L1.0390.90
68_F87_F1.0380.90
562_E597_M1.0360.90
221_L225_H1.0350.90
648_F657_E1.0350.90
369_P716_Y1.0340.90
233_I281_I1.0330.90
552_C556_Q1.0330.90
360_S363_L1.0330.90
167_S173_F1.0310.90
278_A282_I1.0310.90
579_Q695_F1.0310.90
486_E511_R1.0300.90
627_Q642_G1.0280.90
406_V449_I1.0270.90
454_L470_L1.0260.90
39_V110_I1.0250.89
626_L680_T1.0250.89
57_F60_L1.0250.89
566_A569_L1.0250.89
565_V602_L1.0250.89
562_E568_A1.0160.89
467_A501_L1.0130.89
548_S568_A1.0130.89
750_S754_R1.0110.89
280_A284_L1.0090.89
113_K116_E1.0060.89
513_T533_N1.0060.89
35_L60_L1.0040.88
628_L686_S1.0010.88
456_I480_I1.0000.88
95_K124_D1.0000.88
489_L687_I0.9970.88
335_L354_I0.9970.88
414_A461_M0.9970.88
94_T100_Q0.9970.88
57_F87_F0.9960.88
256_I260_S0.9960.88
543_P547_R0.9950.88
403_F453_L0.9940.88
361_P477_H0.9890.88
185_Y204_V0.9850.88
641_I682_A0.9830.87
523_S527_L0.9820.87
365_L481_I0.9810.87
273_T276_D0.9800.87
556_Q559_E0.9790.87
461_M489_L0.9790.87
308_N312_R0.9770.87
346_Y726_L0.9750.87
302_L494_P0.9730.87
316_I361_P0.9730.87
75_H78_F0.9700.87
328_E355_Q0.9700.87
496_Q749_T0.9700.87
605_P611_E0.9690.87
32_Y54_T0.9660.86
704_K733_E0.9660.86
471_F480_I0.9650.86
584_M687_I0.9650.86
657_E662_V0.9600.86
232_A264_Q0.9600.86
536_L739_V0.9560.86
117_E140_V0.9550.86
167_S194_Q0.9520.86
544_T547_R0.9510.86
284_L289_D0.9490.86
501_L507_I0.9460.85
110_I115_A0.9450.85
366_T502_L0.9450.85
418_M421_S0.9450.85
699_V729_C0.9430.85
687_I714_L0.9420.85
619_Y660_A0.9420.85
413_R641_I0.9410.85
563_K568_A0.9390.85
302_L464_I0.9390.85
315_H476_D0.9390.85
564_V567_N0.9390.85
360_S508_P0.9390.85
376_V512_L0.9340.85
339_E345_Q0.9340.85
235_Y239_T0.9340.85
337_E386_E0.9330.85
174_G181_I0.9330.85
566_A570_K0.9300.84
364_L498_L0.9290.84
659_M663_S0.9270.84
700_L726_L0.9270.84
496_Q499_R0.9260.84
348_P514_D0.9250.84
521_G545_K0.9250.84
369_P487_D0.9220.84
126_A129_K0.9200.84
51_V100_Q0.9200.84
429_I470_L0.9200.84
543_P548_S0.9200.84
584_M709_M0.9180.84
595_N684_C0.9180.84
407_L426_A0.9170.83
112_K116_E0.9150.83
558_K597_M0.9150.83
660_A663_S0.9130.83
122_L136_V0.9110.83
568_A571_K0.9110.83
410_P640_D0.9100.83
576_K643_E0.9060.83
214_E218_R0.9010.82
624_K643_E0.9000.82
181_I207_I0.9000.82
175_P181_I0.8980.82
246_H748_Q0.8960.82
597_M601_I0.8900.82
313_V317_A0.8890.82
737_W740_K0.8890.82
190_L194_Q0.8880.81
74_T80_L0.8870.81
564_V729_C0.8840.81
431_R435_W0.8820.81
178_S182_Y0.8810.81
660_A676_F0.8800.81
441_F469_H0.8800.81
232_A261_L0.8800.81
181_I422_T0.8780.81
566_A601_I0.8760.81
626_L685_C0.8720.80
251_T297_C0.8720.80
711_R741_N0.8700.80
579_Q693_S0.8690.80
254_L290_I0.8690.80
626_L682_A0.8640.80
259_Q277_A0.8630.80
283_A287_N0.8630.80
20_V23_V0.8610.79
202_K289_D0.8600.79
145_K148_A0.8600.79
314_K362_M0.8590.79
506_V755_L0.8550.79
237_L290_I0.8540.79
307_Q311_K0.8510.79
717_T720_T0.8470.78
248_Y298_Y0.8460.78
151_L154_A0.8450.78
568_A725_F0.8440.78
567_N729_C0.8420.78
312_R471_F0.8400.78
369_P694_E0.8400.78
612_L673_K0.8390.78
726_L730_G0.8390.78
567_N571_K0.8340.77
641_I685_C0.8340.77
656_K661_V0.8340.77
547_R550_I0.8310.77
657_E660_A0.8300.77
734_A738_G0.8280.77
252_E256_I0.8280.77
441_F444_T0.8260.77
331_F358_L0.8250.76
558_K593_E0.8240.76
207_I212_A0.8200.76
605_P609_R0.8200.76
656_K662_V0.8200.76
642_G718_A0.8170.76
611_E618_V0.8170.76
274_E278_A0.8150.76
558_K568_A0.8140.76
407_L424_L0.8130.75
656_K663_S0.8100.75
569_L572_G0.8100.75
335_L383_L0.8100.75
154_A157_R0.8080.75
290_I313_V0.8070.75
84_A114_T0.8070.75
561_V565_V0.8070.75
335_L355_Q0.8030.75
498_L714_L0.8030.75
127_I131_L0.8030.75
236_T258_T0.8010.74
357_A363_L0.8000.74
563_K566_A0.8000.74
336_G340_E0.7980.74
147_K150_T0.7970.74
181_I200_L0.7950.74
162_E173_F0.7930.74
108_E115_A0.7920.73
195_E199_Q0.7910.73
281_I297_C0.7910.73
573_Y697_I0.7900.73
229_V280_A0.7880.73
562_E570_K0.7860.73
301_S465_W0.7860.73
585_Y628_L0.7850.73
471_F482_I0.7840.73
230_K280_A0.7840.73
559_E597_M0.7840.73
580_V699_V0.7840.73
242_L302_L0.7830.73
704_K737_W0.7830.73
685_C690_S0.7830.73
244_E257_D0.7800.72
524_I722_A0.7790.72
177_L207_I0.7790.72
75_H81_Q0.7760.72
67_T86_H0.7740.72
216_G220_G0.7740.72
76_P83_Q0.7690.71
585_Y686_S0.7680.71
180_K184_A0.7670.71
131_L159_Q0.7670.71
39_V51_V0.7660.71
317_A507_I0.7660.71
582_A628_L0.7650.71
733_E737_W0.7630.71
656_K659_M0.7590.70
417_R693_S0.7590.70
584_M686_S0.7580.70
429_I640_D0.7580.70
406_V454_L0.7560.70
309_V497_V0.7550.70
119_V126_A0.7550.70
657_E661_V0.7540.70
19_T38_K0.7540.70
655_E658_D0.7510.69
431_R632_P0.7510.69
413_R693_S0.7500.69
177_L181_I0.7490.69
194_Q567_N0.7480.69
133_D139_D0.7480.69
518_Q528_A0.7450.69
24_I36_K0.7440.69
546_D550_I0.7430.69
111_G114_T0.7420.69
505_Q511_R0.7410.68
255_I278_A0.7400.68
70_G82_F0.7390.68
658_D673_K0.7390.68
331_F355_Q0.7380.68
413_R417_R0.7380.68
118_I140_V0.7370.68
737_W741_N0.7340.68
241_C614_F0.7330.68
642_G689_K0.7310.67
217_S223_G0.7300.67
504_S755_L0.7300.67
192_K195_E0.7300.67
501_L506_V0.7290.67
461_M689_K0.7280.67
497_V500_D0.7280.67
371_T515_I0.7280.67
428_T432_L0.7270.67
657_E663_S0.7260.67
435_W441_F0.7260.67
366_T486_E0.7250.67
147_K151_L0.7240.67
556_Q560_V0.7230.67
562_E566_A0.7210.66
407_L411_T0.7210.66
411_T461_M0.7210.66
547_R552_C0.7210.66
461_M630_N0.7210.66
455_I483_V0.7200.66
598_L696_P0.7200.66
692_G721_R0.7200.66
357_A481_I0.7180.66
326_F330_E0.7180.66
254_L483_V0.7180.66
192_K199_Q0.7170.66
525_V529_H0.7160.66
558_K562_E0.7160.66
384_Y403_F0.7160.66
452_K478_I0.7140.66
182_Y187_S0.7140.66
555_S559_E0.7130.65
515_I528_A0.7130.65
298_Y750_S0.7130.65
98_I166_I0.7120.65
415_A419_S0.7110.65
582_A585_Y0.7100.65
293_E483_V0.7090.65
406_V418_M0.7090.65
402_A453_L0.7070.65
743_D746_V0.7040.64
416_K665_D0.7040.64
202_K234_L0.7030.64
99_I103_S0.7020.64
181_I184_A0.7020.64
251_T255_I0.7020.64
529_H532_K0.7010.64
85_E88_K0.6990.64
636_V669_M0.6990.64
523_S526_E0.6990.64
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671_F679_F0.6980.64
410_P414_A0.6980.64
441_F448_P0.6980.64
507_I728_L0.6980.64
594_L598_L0.6980.64
233_I236_T0.6950.63
562_E601_I0.6950.63
302_L305_A0.6940.63
129_K139_D0.6930.63
153_G739_V0.6920.63
380_I481_I0.6890.63
251_T292_I0.6870.63
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79_G153_G0.6850.62
344_V644_I0.6840.62
661_V670_T0.6840.62
244_E277_A0.6840.62
208_G213_D0.6830.62
657_E664_F0.6830.62
719_I728_L0.6820.62
352_E355_Q0.6810.62
174_G180_K0.6800.62
694_E717_T0.6800.62
417_R694_E0.6790.62
225_H229_V0.6770.61
285_G297_C0.6770.61
430_H452_K0.6770.61
704_K731_E0.6770.61
646_S668_E0.6760.61
621_T645_T0.6750.61
625_I678_Q0.6740.61
385_G405_I0.6740.61
333_L336_G0.6720.61
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490_P713_N0.6700.61
444_T447_Q0.6690.61
369_P411_T0.6680.60
558_K561_V0.6680.60
412_G415_A0.6680.60
464_I494_P0.6680.60
411_T491_S0.6670.60
164_I254_L0.6660.60
23_V26_H0.6660.60
515_I561_V0.6650.60
376_V494_P0.6650.60
557_I568_A0.6650.60
655_E663_S0.6610.60
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334_A383_L0.6600.60
308_N472_K0.6590.59
208_G215_L0.6590.59
282_I286_E0.6580.59
81_Q460_S0.6580.59
150_T154_A0.6570.59
32_Y52_S0.6560.59
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34_V117_E0.6540.59
338_L346_Y0.6540.59
109_G115_A0.6540.59
353_A376_V0.6530.59
699_V718_A0.6530.59
580_V686_S0.6520.59
254_L297_C0.6520.59
553_G731_E0.6520.59
302_L465_W0.6520.59
248_Y748_Q0.6510.58
366_T420_E0.6510.58
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114_T144_S0.6490.58
505_Q756_S0.6480.58
536_L740_K0.6470.58
492_V630_N0.6450.58
658_D662_V0.6450.58
80_L83_Q0.6450.58
122_L130_I0.6450.58
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634_N706_Y0.6440.58
449_I452_K0.6440.58
465_W468_N0.6430.58
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695_F698_V0.6400.57
36_K40_T0.6400.57
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192_K218_R0.6270.56
567_N570_K0.6260.56
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305_A464_I0.6260.56
175_P186_E0.6250.55
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338_L379_G0.6190.55
427_V685_C0.6190.55
101_Y104_S0.6190.55
528_A532_K0.6190.55
625_I642_G0.6180.55
547_R551_R0.6180.55
54_T57_F0.6180.55
364_L369_P0.6170.54
41_E48_D0.6150.54
348_P352_E0.6150.54
215_L219_M0.6150.54
21_N38_K0.6140.54
539_N746_V0.6140.54
686_S738_G0.6130.54
701_P730_G0.6120.54
488_Q517_R0.6120.54
561_V729_C0.6110.54
23_V33_T0.6100.54
190_L197_P0.6100.54
230_K287_N0.6090.53
213_D228_R0.6080.53
522_S527_L0.6080.53
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114_T118_I0.6080.53
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716_Y721_R0.6060.53
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369_P410_P0.6040.53
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173_F215_L0.6030.53
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547_R554_G0.6020.53
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121_K124_D0.6010.53
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253_Q257_D0.6000.52
637_F640_D0.6000.52
591_I595_N0.6000.52
176_Q386_E0.5990.52
710_L738_G0.5990.52
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343_D618_V0.5980.52
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613_K618_V0.5970.52
131_L155_L0.5970.52
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255_I260_S0.5930.52
68_F84_A0.5930.52
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741_N744_A0.5700.49
222_S521_G0.5700.49
481_I498_L0.5690.49
614_F676_F0.5690.49
505_Q661_V0.5690.49
356_K508_P0.5690.49
21_N25_Y0.5690.49
183_Q186_E0.5690.49
340_E404_P0.5680.49
104_S640_D0.5680.49
311_K533_N0.5670.48
613_K616_D0.5670.48
492_V688_H0.5670.48
202_K288_K0.5660.48
595_N642_G0.5650.48
135_S138_Y0.5640.48
265_S275_M0.5640.48
317_A362_M0.5630.48
644_I647_I0.5630.48
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561_V594_L0.5630.48
314_K755_L0.5620.48
411_T583_P0.5620.48
204_V207_I0.5600.48
346_Y384_Y0.5600.48
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157_R505_Q0.5580.47
117_E141_P0.5580.47
627_Q637_F0.5580.47
214_E330_E0.5580.47
364_L509_T0.5580.47
275_M545_K0.5570.47
461_M490_P0.5570.47
489_L714_L0.5570.47
328_E334_A0.5560.47
435_W686_S0.5560.47
727_I730_G0.5560.47
51_V72_I0.5560.47
560_V729_C0.5550.47
691_Q721_R0.5550.47
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289_D456_I0.5530.47
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141_P481_I0.5510.47
416_K640_D0.5510.47
128_N133_D0.5500.46
307_Q526_E0.5500.46
185_Y199_Q0.5490.46
198_Y228_R0.5480.46
471_F474_I0.5470.46
703_V709_M0.5470.46
365_L511_R0.5460.46
536_L736_E0.5450.46
560_V565_V0.5450.46
675_D680_T0.5450.46
174_G185_Y0.5440.46
110_I123_G0.5440.46
590_G709_M0.5430.46
530_Q538_N0.5430.46
115_A118_I0.5430.46
664_F671_F0.5420.45
292_I297_C0.5410.45
558_K570_K0.5390.45
464_I749_T0.5390.45
704_K734_A0.5370.45
519_A724_K0.5370.45
278_A285_G0.5370.45
97_G280_A0.5370.45
543_P551_R0.5370.45
710_L734_A0.5370.45
69_Y84_A0.5370.45
98_I126_A0.5370.45
380_I557_I0.5360.45
113_K117_E0.5350.45
173_F177_L0.5350.45
146_K150_T0.5340.44
172_G185_Y0.5340.44
709_M741_N0.5340.44
134_A156_Q0.5330.44
461_M512_L0.5330.44
425_P431_R0.5330.44
477_H644_I0.5330.44
734_A737_W0.5330.44
119_V138_Y0.5320.44
115_A119_V0.5320.44
344_V375_T0.5320.44
428_T698_V0.5310.44
49_K96_E0.5300.44
178_S185_Y0.5290.44
173_F211_K0.5290.44
460_S583_P0.5290.44
543_P550_I0.5290.44
28_D59_A0.5280.44
244_E719_I0.5280.44
333_L337_E0.5280.44
122_L155_L0.5280.44
229_V281_I0.5280.44
492_V640_D0.5270.44
178_S186_E0.5270.44
114_T147_K0.5270.44
194_Q197_P0.5270.44
205_E208_G0.5270.44
236_T257_D0.5260.44
417_R640_D0.5260.44
196_N199_Q0.5260.44
166_I169_N0.5250.43
715_L738_G0.5250.43
493_G689_K0.5250.43
382_E447_Q0.5250.43
416_K637_F0.5240.43
167_S179_M0.5240.43
515_I518_Q0.5240.43
746_V752_K0.5240.43
414_A417_R0.5240.43
88_K218_R0.5240.43
29_T71_K0.5230.43
153_G343_D0.5230.43
473_A500_D0.5230.43
574_T577_D0.5230.43
47_E65_T0.5220.43
112_K115_A0.5220.43
123_G126_A0.5220.43
170_Q178_S0.5220.43
528_A679_F0.5210.43
62_E92_P0.5210.43
617_V621_T0.5210.43
549_F735_L0.5210.43
288_K740_K0.5200.43
173_F181_I0.5200.43
86_H625_I0.5200.43
364_L510_V0.5190.43
155_L475_P0.5180.43
655_E661_V0.5180.43
361_P580_V0.5180.43
195_E354_I0.5180.43
64_E749_T0.5170.42
141_P144_S0.5170.42
317_A501_L0.5170.42
277_A284_L0.5170.42
498_L502_L0.5160.42
163_Q166_I0.5160.42
706_Y709_M0.5160.42
368_G463_D0.5150.42
254_L515_I0.5150.42
225_H228_R0.5150.42
119_V483_V0.5150.42
262_L534_G0.5130.42
469_H472_K0.5130.42
491_S640_D0.5130.42
377_I483_V0.5130.42
368_G695_F0.5130.42
370_G488_Q0.5120.42
114_T123_G0.5120.42
377_I624_K0.5120.42
24_I294_D0.5120.42
342_M382_E0.5120.42
553_G672_T0.5110.42
644_I673_K0.5110.42
429_I461_M0.5100.42
535_L538_N0.5100.42
621_T644_I0.5100.42
371_T512_L0.5100.42
332_L335_L0.5100.42
412_G466_L0.5100.42
749_T752_K0.5100.42
435_W626_L0.5090.42
147_K159_Q0.5090.42
255_I282_I0.5090.42
66_Y293_E0.5080.41
313_V364_L0.5080.41
592_N680_T0.5080.41
738_G741_N0.5080.41
539_N672_T0.5080.41
598_L601_I0.5080.41
482_I710_L0.5070.41
500_D590_G0.5070.41
743_D753_N0.5060.41
162_E167_S0.5060.41
139_D156_Q0.5060.41
123_G127_I0.5060.41
276_D279_N0.5060.41
412_G693_S0.5060.41
503_A533_N0.5050.41
35_L57_F0.5050.41
527_L735_L0.5040.41
369_P525_V0.5040.41
558_K644_I0.5040.41
745_T756_S0.5040.41
115_A417_R0.5040.41
375_T421_S0.5030.41
532_K716_Y0.5030.41
711_R744_A0.5030.41
559_E562_E0.5030.41
349_S512_L0.5020.41
364_L531_M0.5020.41
302_L481_I0.5020.41
209_F412_G0.5010.41
290_I667_N0.5010.41
117_E482_I0.5010.41
194_Q481_I0.5010.41
68_F89_K0.5000.41
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3e1sA 1 0.6341 100 0.474 Contact Map
1w36D 1 0.5827 100 0.559 Contact Map
3upuA 1 0.4449 100 0.707 Contact Map
4l0jA 2 0.1667 100 0.772 Contact Map
2gk6A 1 0.6053 100 0.792 Contact Map
4n0nA 1 0.4737 100 0.8 Contact Map
1omhA 1 0.2544 100 0.807 Contact Map
3l6tA 2 0.1754 100 0.809 Contact Map
4pj3A 1 0.7719 100 0.81 Contact Map
2wjyA 1 0.7318 100 0.811 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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